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Plasma for prevention and treatment of glycocalyx degradation in trauma and sepsis Crit. Care (IF 8.8) Pub Date : 2024-07-20 M. S. Kravitz, N. Kattouf, I. J. Stewart, A. A. Ginde, E. P. Schmidt, N. I. Shapiro
The endothelial glycocalyx, a gel-like layer that lines the luminal surface of blood vessels, is composed of proteoglycans, glycoproteins, and glycosaminoglycans. The endothelial glycocalyx plays an essential role in vascular homeostasis, and its degradation in trauma and sepsis can lead to microvascular dysfunction and organ injury. While there are no proven therapies for preventing or treating endothelial
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Activity, triage levels and impact of the pandemic on hospital emergency departments: A multicentre cross‐sectional study J. Adv. Nurs. (IF 3.8) Pub Date : 2024-07-20 Cristina Font‐Cabrera, Maria Eulàlia Juvé‐Udina, Jordi Adamuz, Montserrat Diaz Membrives, Núria Fabrellas, Eva Maria Guix‐Comellas
AimDescribe the activity of hospital emergency departments (EDs) and the sociodemographic profile of patients in the eight public hospitals in Spain, according to the different triage levels, and to analyse the impact of the SARS‐CoV‐2 pandemic on patient flow.DesignAn observational, descriptive, cross‐sectional and retrospective study was carried out.MethodsThree high‐tech public hospitals and five
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Association between whole blood ratio and risk of mortality in massively transfused trauma patients: retrospective cohort study Crit. Care (IF 8.8) Pub Date : 2024-07-19 Makoto Aoki, Toshikazu Abe, Akira Komori, Morihiro Katsura, Kazuhide Matsushima
Although whole blood (WB) transfusion was reported to improve survival in trauma patients with hemorrhagic shock, little is known whether a higher proportion of WB is associated with an improved survival. This study aimed to evaluate the association between whole blood ratio (WBR) and the risk of mortality in trauma patients requiring massive blood transfusion. We performed a retrospective cohort study
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Hyperoxemia may be more beneficial for patients with sepsis Crit. Care (IF 8.8) Pub Date : 2024-07-19 Liyuan Peng, Xiaoming Qin, Lvlin Chen
To the Editor, We have read with great interest the clinical study by Dong-gon et al. published in Critical Care [1]. The study showed a robust correlation between higher PaO2 (≥ 80 mmHg) during the first three ICU days and a lower 28-day mortality. The optimal PaO2 range represents an intriguing and significant subject for exploration. Our department is the general Intensive Care Unit (ICU) of a tertiary
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Influence of health insurance on withdrawal of life sustaining treatment for patients with isolated traumatic brain injury: a retrospective multi-center observational cohort study Crit. Care (IF 8.8) Pub Date : 2024-07-18 Armaan K. Malhotra, Husain Shakil, Ahmad Essa, Francois Mathieu, Shaurya Taran, Jetan Badhiwala, Yingshi He, Eva Y. Yuan, Abhaya V. Kulkarni, Jefferson R. Wilson, Avery B. Nathens, Christopher D. Witiw
Healthcare inequities for patients with traumatic brain injury (TBI) represent a major priority area for trauma quality improvement. We hypothesized a relationship between health insurance status and timing of withdrawal of life sustaining treatment (WLST) for adults with severe TBI. This multicenter retrospective observational cohort study utilized data collected between 2017 and 2020. We identified
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High flow nasal cannula oxygen therapy versus non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease with acute-moderate hypercapnic respiratory failure: a randomized controlled non-inferiority trial Crit. Care (IF 8.8) Pub Date : 2024-07-18 Dingyu Tan, Bingxia Wang, Peng Cao, Yunyun Wang, Jiayan Sun, Ping Geng, Joseph Harold Walline, Yachao Wang, Chenlong Wang
Although cumulative studies have demonstrated a beneficial effect of high-flow nasal cannula oxygen (HFNC) in acute hypercapnic respiratory failure, randomized trials to compare HFNC with non-invasive ventilation (NIV) as initial treatment in acute exacerbations of chronic obstructive pulmonary disease (AECOPD) patients with acute-moderate hypercapnic respiratory failure are limited. The aim of this
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Guiding resuscitation in shock: base excess or lactate? Crit. Care (IF 8.8) Pub Date : 2024-07-18 Micah Liam Arthur Heldeweg, Thomas Langer, František Duška
Base excess (BE) is a widely used parameter derived from blood gas analysis. A recent international study showed that 40% of surveyed anesthesia and critical care clinicians use BE to guide (intraoperative) fluid management, and that 25% of respondents prefer BE over lactate [1]. This is surprising as lactate production is directly increased by hypovolemia-associated tissue hypoxia, whilst BE is a
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Early physical rehabilitation dosage in the intensive care unit associates with hospital outcomes after critical COVID-19 Crit. Care (IF 8.8) Pub Date : 2024-07-18 Kirby P. Mayer, Evan Haezebrouck, Lori M. Ginoza, Clarisa Martinez, Minnie Jan, Lori A. Michener, Lindsey E. Fresenko, Ashley A. Montgomery-Yates, Anna G. Kalema, Amy M. Pastva, Michelle Biehl, Matthew F. Mart, Joshua K. Johnson
To examine the relationship between physical rehabilitation parameters including an approach to quantifying dosage with hospital outcomes for patients with critical COVID-19. Retrospective practice analysis from March 5, 2020, to April 15, 2021. Intensive care units (ICU) at four medical institutions. n = 3780 adults with ICU admission and diagnosis of COVID-19. We measured the physical rehabilitation
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Prioritising deteriorating patients using time-to-event analysis: prediction model development and internal–external validation Crit. Care (IF 8.8) Pub Date : 2024-07-17 Robin Blythe, Rex Parsons, Adrian G. Barnett, David Cook, Steven M. McPhail, Nicole M. White
Binary classification models are frequently used to predict clinical deterioration, however they ignore information on the timing of events. An alternative is to apply time-to-event models, augmenting clinical workflows by ranking patients by predicted risks. This study examines how and why time-to-event modelling of vital signs data can help prioritise deterioration assessments using lift curves,
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Measuring the relationship between reciprocity behaviour and technology readiness of nursing staff working in residential care and community nursing: A cross‐sectional study J. Adv. Nurs. (IF 3.8) Pub Date : 2024-07-19 Elvira Coffetti, Wolter Paans, Wim P. Krijnen, Petrie F. Roodbol, Evelyn J. Finnema, Jelly Zuidersma
AimThe aim of this study is to measure how collaborative factors are associated with the technology readiness of nursing staff working in residential care and community nursing. The Reciprocity Instrument and Technology Readiness Index 2.0 were applied to measure this association.DesignA cross‐sectional survey was conducted between October 2020 and January 2021.MethodsThe Technology Readiness Index
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Impact of withholding early parenteral nutrition on 2-year mortality and functional outcome in critically ill adults Intensive Care Med. (IF 27.1) Pub Date : 2024-07-17 Michael P. Casaer, Hendrik Stragier, Greet Hermans, Alexandra Hendrickx, Pieter J. Wouters, Jasperina Dubois, Fabian Guiza, Greet Van den Berghe, Jan Gunst
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Pulmonary herpes simplex virus and cytomegalovirus in patients with acute respiratory distress syndrome related to COVID-19 Intensive Care Med. (IF 27.1) Pub Date : 2024-07-17 Leonoor S. Boers, Frank van Someren Gréve, Jarne M. van Hattem, Justin de Brabander, Tom Zwaan, Hugo van Willigen, Marion Cornelissen, Menno de Jong, Tom van der Poll, JanWillem Duitman, Janke Schinkel, Lieuwe D. J. Bos
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Examining inequality in scientific production: a focus on critical care publications and global economic disparities Intensive Care Med. (IF 27.1) Pub Date : 2024-07-17 Renato Daltro-Oliveira, Amanda Quintairos, Laura I. Oliveira Santos, Jorge I. Figueira Salluh, Antonio P. Nassar
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Identification and transcriptomic assessment of latent profile pediatric septic shock phenotypes Crit. Care (IF 8.8) Pub Date : 2024-07-17 Mihir R. Atreya, Min Huang, Andrew R. Moore, Hong Zheng, Yehudit Hasin-Brumshtein, Julie C. Fitzgerald, Scott L. Weiss, Natalie Z. Cvijanovich, Michael T. Bigham, Parag N. Jain, Adam J. Schwarz, Riad Lutfi, Jeffrey Nowak, Neal J. Thomas, Michael Quasney, Mary K. Dahmer, Torrey Baines, Bereketeab Haileselassie, Andrew J. Lautz, Natalja L. Stanski, Stephen W. Standage, Jennifer M. Kaplan, Basilia Zingarelli
Sepsis poses a grave threat, especially among children, but treatments are limited owing to heterogeneity among patients. We sought to test the clinical and biological relevance of pediatric septic shock subclasses identified using reproducible approaches. We performed latent profile analyses using clinical, laboratory, and biomarker data from a prospective multi-center pediatric septic shock observational
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Bracing for the next wave: A critical incident study of frontline decision‐making, adaptation and learning in ambulance care during COVID‐19 J. Adv. Nurs. (IF 3.8) Pub Date : 2024-07-17 Ann‐Therese Hedqvist, Mats Holmberg, Petronella Bjurling‐Sjöberg, Mirjam Ekstedt
AimTo explore frontline decision‐making, adaptation, and learning in ambulance care during the evolving COVID‐19 pandemic.DesignDescriptive and interpretative qualitative study.MethodsTwenty‐eight registered nurses from the Swedish ambulance services described 56 critical incidents during the COVID‐19 pandemic through free‐text questionnaires. The material was analysed using the Critical Incident Technique
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Achieving consensus on the key elements of a nurse‐led multidisciplinary chronic heart failure service in Thailand: An e‐Delphi study J. Adv. Nurs. (IF 3.8) Pub Date : 2024-07-17 Apinya Koontalay, Mari Botti, Anastasia Hutchinson
AimsTo describe the outcomes of an e(electronic)‐Delphi survey used to achieve consensus on the essential elements that should be included in a multidisciplinary, nurse‐led service for patients with chronic heart failure (CHF).DesignThe study design was based on a three‐round e‐Delphi survey.MethodsA series of three survey rounds were used to gather expert opinions and achieve consensus on the key
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Keeping the ‘quality’ in qualitative research: Embracing technology to enhance participation in qualitative interviews J. Adv. Nurs. (IF 3.8) Pub Date : 2024-07-17 Michelle Cleary, Catherine Hungerford, Colleen Johnston‐Devin, Sancia West, Debra Jackson
Qualitative researchers seek to understand and explore human values, beliefs and experiences, including research participants' attribution of meaning to these factors. The topics under investigation often call for research participants to share their experiences of challenging and traumatic events. Participants in qualitative research may make themselves vulnerable when asked to share details of events
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Sex representation within intensive care trials in Australia and New Zealand Intensive Care Med. (IF 27.1) Pub Date : 2024-07-16 Lucy Modra, Allison Bone, David Pilcher, Mark Woodward, Kelly Thompson
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Operator independent continuous ultrasound monitoring of diaphragm excursion predicts successful weaning from mechanical ventilation: a prospective observational study Crit. Care (IF 8.8) Pub Date : 2024-07-16 Alexandre Demoule, Quentin Fossé, Alain Mercat, Daniel Bergum, Sara Virolle, Côme Bureau, Marit Mellemseter, Rafaël Guichou, Thomas Similowski, Martin Dres, Satar Mortaza
In mechanically ventilated patients, diaphragm ultrasound can identify diaphragm weakness and predict weaning failure. We evaluated whether a novel operator-independent ultrasound-based medical device allowing continuous monitoring of the diaphragm (CUSdi) could reliably (1) measure diaphragm excursion (EXdi) and peak contraction velocity (PCVdi), (2) predict weaning outcome, and (3) approximate transdiaphragmatic
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Utility and rationale for continuous EEG monitoring: a primer for the general intensivist Crit. Care (IF 8.8) Pub Date : 2024-07-16 Ribal Bitar, Usaamah M. Khan, Eric S. Rosenthal
This review offers a comprehensive guide for general intensivists on the utility of continuous EEG (cEEG) monitoring for critically ill patients. Beyond the primary role of EEG in detecting seizures, this review explores its utility in neuroprognostication, monitoring neurological deterioration, assessing treatment responses, and aiding rehabilitation in patients with encephalopathy, coma, or other
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Clinical characteristics and outcomes of immunocompromised critically ill patients with cytomegalovirus end-organ disease: a multicenter retrospective cohort study Crit. Care (IF 8.8) Pub Date : 2024-07-16 Sara Fernández, Ignacio Grafia, Olivier Peyrony, Emmanuel Canet, Clara Vigneron, Clément Monet, Nahéma Issa, Maxens Decavele, Anne-Sophie Moreau, Alexandre Lautrette, Guillaume Lacave, Guillaume Morel, Cyril Cadoz, Laurent Argaud, Liran Statlender, Karam Azem, Jean-Pierre Quenot, Olivier Lesieur, Javier Fernández, Marta Farrero, Mª Ángeles Marcos, Virgine Lemiale, Pedro Castro, Élie Azoulay
Cytomegalovirus (CMV) infection in patients with cellular immune deficiencies is associated with significant morbidity and mortality. However, data on CMV end-organ disease (CMV-EOD) in critically ill, immunocompromised patients are scarce. Our objective here was to describe the clinical characteristics and outcomes of CMV-EOD in this population. We conducted a multicenter, international, retrospective
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Early bolus epinephrine administration during pediatric cardiopulmonary resuscitation for bradycardia with poor perfusion: an ICU-resuscitation study Crit. Care (IF 8.8) Pub Date : 2024-07-16 Amanda J. O’Halloran, Ron W. Reeder, Robert A. Berg, Tageldin Ahmed, Michael J. Bell, Robert Bishop, Matthew Bochkoris, Candice Burns, Joseph A. Carcillo, Todd C. Carpenter, J. Michael Dean, J. Wesley Diddle, Myke Federman, Richard Fernandez, Ericka L. Fink, Deborah Franzon, Aisha H. Frazier, Stuart H. Friess, Kathryn Graham, Mark Hall, David A. Hehir, Christopher M. Horvat, Leanna L. Huard, Martha
Half of pediatric in-hospital cardiopulmonary resuscitation (CPR) events have an initial rhythm of non-pulseless bradycardia with poor perfusion. Our study objectives were to leverage granular data from the ICU-RESUScitation (ICU-RESUS) trial to: (1) determine the association of early epinephrine administration with survival outcomes in children receiving CPR for bradycardia with poor perfusion; and
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The Caring Life Course Theory: Opening new frontiers in care—A cardiac rehabilitation example J. Adv. Nurs. (IF 3.8) Pub Date : 2024-07-16 Maria Alejandra Pinero de Plaza, Claire Hutchinson, Alline Beleigoli, Matthew Tieu, Michael Lawless, Tiffany Conroy, Rebecca Feo, Robyn A. Clark, Hila Dafny, Penelope McMillan, Regina Allande‐Cussó, Alison A. Kitson
Aim(s)To operationalize the Caring Life Course Theory (CLCT) as a framework for improving cardiac rehabilitation (CR) engagement and informing ways to address disparities in rural, low socio‐economic areas.MethodsA secondary analysis of data collected from 15 CR programmes to identify CR patterns through the CLCT lens using a mixed‐methods approach. All analytical processes were conducted in NVivo
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Health promotion nursing interventions for female breast cancer survivors: A scoping review J. Adv. Nurs. (IF 3.8) Pub Date : 2024-07-16 Pegah Torabi, Maud‐Christine Chouinard, Marie‐Maxim Sévigny, Karine Bilodeau
AimMap the existing health promotion nursing interventions for female breast cancer survivors (BCS) to describe the approaches used and the characteristics of these interventions in the available studies.DesignA scoping review.Data SourceFive electronic databases were systematically searched for eligible studies, published between 2002 and 2022.MethodsFollowing the Joanna Briggs Institute's methodology
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Absolute values of regional ventilation-perfusion mismatch in patients with ARDS monitored by electrical impedance tomography and the role of dead space and shunt compensation Crit. Care (IF 8.8) Pub Date : 2024-07-15 Marco Leali, Ines Marongiu, Elena Spinelli, Valentina Chiavieri, Joaquin Perez, Mauro Panigada, Giacomo Grasselli, Tommaso Mauri
Assessment of regional ventilation/perfusion (V′/Q) mismatch using electrical impedance tomography (EIT) represents a promising advancement for personalized management of the acute respiratory distress syndrome (ARDS). However, accuracy is still hindered by the need for invasive monitoring to calibrate ventilation and perfusion. Here, we propose a non-invasive correction that uses only EIT data and
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Integrated clustering of multiple immune marker trajectories reveals different immunotypes in severely injured patients Crit. Care (IF 8.8) Pub Date : 2024-07-15 Maxime Bodinier, Estelle Peronnet, Jean-François Llitjos, Louis Kreitmann, Karen Brengel-Pesce, Thomas Rimmelé, Aurore Fleurie, Julien Textoris, Fabienne Venet, Delphine Maucort-Boulch, Guillaume Monneret
The immune response of critically ill patients, such as those with sepsis, severe trauma, or major surgery, is heterogeneous and dynamic, but its characterization and impact on outcomes are poorly understood. Until now, the primary challenge in advancing our understanding of the disease has been to concurrently address both multiparametric and temporal aspects. We used a clustering method to identify
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Efficacy and safety of different polymyxin-containing regimens for the treatment of pneumonia caused by multidrug-resistant gram-negative bacteria: a systematic review and network meta-analysis Crit. Care (IF 8.8) Pub Date : 2024-07-14 Yi Zhou, Guizhong Wang, Ying Zhao, Weijia Chen, Xuyan Chen, Yuqi Qiu, Yuanyu Liu, Shuqi Wu, Jianbin Guan, Ping Chang, Yong Liu, Zhanguo Liu
The optimal administration of polymyxins for treating multidrug-resistant gram-negative bacterial (MDR-GNB) pneumonia remains unclear. This study aimed to systematically assess the efficacy and safety of three polymyxin-containing regimens by conducting a comprehensive network meta-analysis. We comprehensively searched nine databases. Overall mortality was the primary outcome, whereas the secondary
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From Traditional Typing to Intelligent Insights: A Narrative Review of Directions Toward Targeted Therapies in Delirium. Crit. Care Med. (IF 7.7) Pub Date : 2024-07-15 Kelly M Potter, Niall T Prendergast, J Gordon Boyd
Delirium is a heterogeneous syndrome characterized by an acute change in level of consciousness that is associated with inattention and disorganized thinking. Delirium affects most critically ill patients and is associated with poor patient-oriented outcomes such as increased mortality, longer ICU and hospital length of stay, and worse long-term cognitive outcomes. The concept of delirium and its subtypes
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Society of Critical Care Medicine and American Society of Health-System Pharmacists Guideline for the Prevention of Stress-Related Gastrointestinal Bleeding in Critically Ill Adults. Crit. Care Med. (IF 7.7) Pub Date : 2024-07-15 Robert MacLaren, Joanna C Dionne, Anders Granholm, Waleed Alhazzani, Paul M Szumita, Keith Olsen, Jeffrey F Barletta, Morten Hylander Møller, Constantine J Karvellas, Paul Wischmeyer, Ashley DePriest, Victor Carlos, Debora Argetsinger, John J Carothers, Rosemary Lee, Lena Napolitano, Dan Perri, Douglas F Naylor
Critically ill adults can develop stress-related mucosal damage from gastrointestinal hypoperfusion and reperfusion injury, predisposing them to clinically important stress-related upper gastrointestinal bleeding (UGIB).
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Māori nurse practitioners: The intersection of patient safety and culturally safe care from an Indigenous lens J. Adv. Nurs. (IF 3.8) Pub Date : 2024-07-15 Ebony Komene, Josephine Davis, Rhoena Davis, Robyn O'Dwyer, Kate Te Pou, Chantelle Dick, Lisa Sami, Coral Wiapo, Sue Adams
BackgroundDynamic and complex health systems require innovative and adaptive solutions to support patient safety and achieve equitable health outcomes for Indigenous populations. Understanding the ways by which Indigenous (and specifically Māori) nurse practitioners (NPs) practice patient safety is key to enhancing Indigenous health outcomes in predominantly westernized healthcare systems.AimTo describe
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Factors influencing general practice nurse's implementation of culturally responsive care, using normalization process theory: A cross‐sectional study J. Adv. Nurs. (IF 3.8) Pub Date : 2024-07-15 S. Oakley, M. Manning, A. Macfarlane, A. Murphy, O. Loftus‐Moran, K. Markey
AimsTo explore levers and barriers to providing culturally responsive care for general practice nurses (GPNs) using normalization process theory.DesignA self‐administered online cross‐sectional survey.MethodsA participatory co‐designed adapted version of the normalization of complex interventions measure (NoMAD) validated tool was distributed to a convenience sample of GPNs between December 2022 and
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Enhancing sepsis biomarker development: key considerations from public and private perspectives Crit. Care (IF 8.8) Pub Date : 2024-07-13 Jean-Francois Llitjos, Enitan D. Carrol, Marcin F. Osuchowski, Marc Bonneville, Brendon P. Scicluna, Didier Payen, Adrienne G. Randolph, Stephan Witte, Jesus Rodriguez-Manzano, Bruno François
Implementation of biomarkers in sepsis and septic shock in emergency situations, remains highly challenging. This viewpoint arose from a public–private 3-day workshop aiming to facilitate the transition of sepsis biomarkers into clinical practice. The authors consist of international academic researchers and clinician-scientists and industry experts who gathered (i) to identify current obstacles impeding
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Transgender people's experiences of hospitalization: A qualitative metasynthesis J. Adv. Nurs. (IF 3.8) Pub Date : 2024-07-14 Nicoletta Dasso, Giulia Ottonello, Mark Hayter, Gianluca Catania, Giulia Risso, Giuseppe Aleo, Milko Zanini, Loredana Sasso, Annamaria Bagnasco
AimTo identify, synthesize, and interpret the scientific literature on the experience, perspectives, and feelings of transgender people during hospitalization.DesignA qualitative metasynthesis.Data SourcesPubMed, CINAHL and PSYCHINFO were consulted in March 2024.MethodsA literature review was conducted following Sandelowski and Barroso's four‐step metasynthesis methodology. The article selection process
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Transition from homelessness to becoming housed: A qualitative study J. Adv. Nurs. (IF 3.8) Pub Date : 2024-07-14 Myung Sun Hyun, Kyoung A Nam, Eunyoung Park, Jin Ju Kim
AimTo explore the transitional experiences of becoming housed from homelessness.DesignA qualitative descriptive study.MethodsData were collected during 2017 and 2018 using a semi‐structured interview method with 10 former homeless people who became housed at the time of the study. The grounded theory method was used to analyse qualitative data.Results‘Desire to keep a place to stretch out and lie down’
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Paediatric nurses' perspectives on artificial intelligence applications: A cross‐sectional study of concerns, literacy levels and attitudes J. Adv. Nurs. (IF 3.8) Pub Date : 2024-07-14 Damla Özçevik Subaşi, Aylin Akça Sümengen, Remziye Semerci, Enes Şimşek, Gökçe Naz Çakır, Ebru Temizsoy
AimsThis study aimed to explore the correlation between artificial intelligence (AI) literacy, AI anxiety and AI attitudes among paediatric nurses, as well as identify the influencing factors on paediatric nurses' AI attitudes.DesignA descriptive, correlational and cross‐sectional research.MethodsThis study was conducted between January and February 2024 with 170 nurses actively working in paediatric
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Leading through the COVID‐19 pandemic: Experiences of UK Executive Nurse Directors J. Adv. Nurs. (IF 3.8) Pub Date : 2024-07-14 Alison H. James, Rebecca Dimond, Aled Jones, Dianne Watkins, Daniel Kelly
AimTo explore the challenges experienced by Executive Nurse Directors during the COVID‐19 pandemic, and to inform future nursing leadership strategies.DesignA qualitative research project involving interviews with 21 Executive Nurse Directors from England and Wales.MethodsParticipants were purposively sampled and recruited through Chief Nursing Officers and nursing leadership networks. Semi‐structured
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A network analysis of self‐compassion and burnout in a sample of nurses J. Adv. Nurs. (IF 3.8) Pub Date : 2024-07-14 Chunqin Liu, Ying Zhou, Qing Luo, Liqin Song, JiaJian Xiao, Wenying Tan, Chuyuan Miao, Graeme Drummond Smith
BackgroundIn the nursing profession, the concept of self‐compassion has been associated with burnout. However, to date, the fine‐grained relationships between different dimensions of self‐compassion and symptoms of burnout have not been investigated. Network analysis provides a new avenue for exploring the fine‐grained correlation paths of two related variables.AimTo analyse the nuanced associations
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‘In our culture, we come when you die’: Qualitative descriptive analysis of end‐of‐life perspectives in a reservation‐based community J. Adv. Nurs. (IF 3.8) Pub Date : 2024-07-14 Katie E. Nelson, Kathleen Adams, Michelle Kahn‐John, Patricia M. Davidson, Betty Ferrell, Mumtahana Meah, Claire Petchler, Adriann Ricker, Kassie Runsabove, Alicia Werk, Rebecca Wright, Teresa N. Brockie
AimTo explore (1) perspectives and attitudes of Native Americans regarding transitions from serious illness to death, and (2) awareness about hospice and palliative care service models in a Great Plains reservation‐based community.DesignQualitative descriptive study.MethodsCommunity members and clinicians were invited to participate in a semi‐structured focus group or interview by Tribal Advisory Board
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A structural equation model of the impacts of nurses' psychological safety and psychological contract breach J. Adv. Nurs. (IF 3.8) Pub Date : 2024-07-14 Marjo Ring, Marja Hult
AimTo investigate the effects of psychological contract breach and psychological safety on health and well‐being outcomes among nurses.DesignA cross‐sectional study.MethodsData were gathered from members of the Finnish social and healthcare workers' trade union (n = 4575) in February 2023. This study focused on data from 3260 nurses. Structural equation modelling was employed to firstly explain burnout
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Resilience after severe critical illness: a prospective, multicentre, observational study (RESIREA) Crit. Care (IF 8.8) Pub Date : 2024-07-12 Alice Mathieu, Jean Reignier, Amélie Le Gouge, Gaetan Plantefeve, Jean-Paul Mira, Laurent Argaud, Pierre Asfar, Julio Badie, Nicolae-Vlad Botoc, Hoang-Nam Bui, Delphine Chatellier, Louis Chauvelot, Christophe Cracco, Michael Darmon, Agathe Delbove, Jérôme Devaquet, Louis-Marie Dumont, Olivier Gontier, Samuel Groyer, Yannick Hourmant, Samir Jaber, Fabien Lambiotte, Benjamin Madeux, Julien Maizel, Olivier
Critical-illness survivors may experience post-traumatic stress disorder (PTSD) and quality-of-life impairments. Resilience may protect against psychological trauma but has not been adequately studied after critical illness. We assessed resilience and its associations with PTSD and quality of life, and also identified factors associated with greater resilience. This prospective, multicentre, study
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The role of ‘familiarity’ and ‘normality’ in supporting transition to end of life care in paediatric oncology: A qualitative study J. Adv. Nurs. (IF 3.8) Pub Date : 2024-07-13 Daniel Kelly, Mia Closs, Rachel McAndrew, Pam Smith
AimThe aim of this study was to explore factors that helped when a child with cancer transitioned to end of life care in a hospital setting.DesignQualitative exploratory design using reflexive thematic analysis.MethodsIn‐depth, semi‐structured interviews were carried out with 7 sets of bereaved parents and 10 health professionals from one specialist paediatric oncology centre. Results were shared with
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Mechanisms of the influence of proactive personality on nurses' sense of social responsibility: A structural equation modelling study J. Adv. Nurs. (IF 3.8) Pub Date : 2024-07-13 Dexiu Yan, Lan Chen, Mengyao Li, Yuanyuan Zhang, Yaqing Zhang, Yili Zhang, Jian Chang
AimTo explore the mechanism of proactive personality influence on nurses' sense of social responsibility through a serial multiple mediation model of volunteering motivation and self‐efficacy.DesignFurther analysis of a cross‐sectional and survey‐based study.MethodsIn June 2023, a study was conducted with 722 Chinese nurses from four hospitals. Data were collected using the Proactive Personality Scale
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Prognostic value of serial (1,3)-β-d-glucan measurements in ICU patients with invasive candidiasis Crit. Care (IF 8.8) Pub Date : 2024-07-12 Simone Carelli, Brunella Posteraro, Riccardo Torelli, Elena De Carolis, Maria Sole Vallecoccia, Rikardo Xhemalaj, Salvatore Lucio Cutuli, Eloisa Sofia Tanzarella, Antonio Maria Dell’Anna, Gianmarco Lombardi, Fabiola Cammarota, Alessandro Caroli, Domenico Luca Grieco, Maurizio Sanguinetti, Massimo Antonelli, Gennaro De Pascale
To determine whether a decrease in serum (1,3)-β-d-glucan (BDG) was associated with reduced mortality and to investigate the performance of BDG downslope in predicting clinical outcome in invasive candidiasis. Observational cohort study in ICU patients over a ten-year period (2012–2022) in Italy. Proven invasive candidiasis with at least 2 BDG determinations were considered. In the study population
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Implications of sedation during the use of noninvasive ventilation in children with acute respiratory failure (SEDANIV Study) Crit. Care (IF 8.8) Pub Date : 2024-07-11 Lorena Bermúdez-Barrezueta, Juan Mayordomo-Colunga, María Miñambres-Rodríguez, Susana Reyes, Juan Valencia-Ramos, Yolanda Margarita Lopez-Fernandez, Mikel Mendizábal-Diez, Ana Vivanco-Allende, Alba Palacios-Cuesta, Lidia Oviedo-Melgares, José Luis Unzueta-Roch, Jorge López-González, María Teresa Jiménez-Villalta, Maite Cuervas-Mons Tejedor, Lourdes Artacho González, Ainhoa Jiménez Olmos, Martí Pons-Òdena
The objective of this study was to analyze the effects of sedation administration on clinical parameters, comfort status, intubation requirements, and the pediatric intensive care unit (PICU) length of stay (LOS) in children with acute respiratory failure (ARF) receiving noninvasive ventilation (NIV). Thirteen PICUs in Spain participated in a prospective, multicenter, observational trial from January
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Bayesian networks may allow better performance and usability than logistic regression Crit. Care (IF 8.8) Pub Date : 2024-07-11 Jared M. Wohlgemut, Erhan Pisirir, Rebecca S. Stoner, Evangelia Kyrimi, Barbaros Yet, William Marsh, Zane B. Perkins, Nigel R. M. Tai
We read with great interest the article by Brac et al. entitled “Development and validation of the TIC score for early detection of traumatic coagulopathy upon hospital admission: a cohort study” [1]. We congratulate the authors on their work focusing on trauma-induced coagulopathy (TIC), a key outcome early after trauma that increases the risk of mortality and may be treated and potentially reversed
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The work of palliative care from the perspectives of district nurses: A qualitative study J. Adv. Nurs. (IF 3.8) Pub Date : 2024-07-12 Jackie Robinson, Hetty Goodwin, Lisa Williams, Natalie Anderson, Jenny Parr, Rebekah Irwin, Merryn Gott
AimTo explore the work of palliative care from the perspectives of district nurses with a focus on the strategies they use to achieve positive outcomes for patients.DesignAn exploratory descriptive qualitative study.MethodsA combination of group and individual interviews using semi‐structured interviewing were used to explore district nurses' views of providing palliative care across two large urban
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Lower or higher oxygenation targets in the intensive care unit: an individual patient data meta-analysis Intensive Care Med. (IF 27.1) Pub Date : 2024-07-11 Frederik Mølgaard Nielsen, Thomas L. Klitgaard, Niels Henrik Bruun, Morten H. Møller, Olav L. Schjørring, Bodil S. Rasmussen
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Left and right atrial strain analysis to predicting new-onset atrial fibrillation in patients with septic shock: a single-center retrospective echocardiography study Crit. Care (IF 8.8) Pub Date : 2024-07-11 Christophe Beyls, Alexis Hermida, Camille Daumin, Max-Paul Delmotte, Arnaud Nsiku, Pierre Huette, Camille Bunelle, Hervé Dupont, Osama Abou-Arab, Yazine Mahjoub
To the Editor, New-onset atrial fibrillation (NOAF) is the most common arrhythmogenic complication in septic shock patients, significantly increasing the risk of thromboembolic events and mortality [1]. Septic shock may rapidly induce septic cardiomyopathy, leading to atrial remodeling and fibrosis, which predisposes patients to NOAF. Although bedside transthoracic echocardiography (TTE) is commonly
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The paradox of workplace violence in the intensive care unit: a focus group study Crit. Care (IF 8.8) Pub Date : 2024-07-11 Fredric Sjöberg, Martin Salzmann-Erikson, Eva Åkerman, Eva Joelsson-Alm, Anna Schandl
Conflicts with patients and relatives occur frequently in intensive care units (ICUs), driven by factors that are intensified by critical illness and its treatments. A majority of ICU healthcare professionals have experienced verbal and/or physical violence. There is a need to understand how healthcare professionals in ICUs experience and manage this workplace violence. A qualitative descriptive analysis
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Fluid management for sepsis-induced hypotension in patients with advanced chronic kidney disease: a secondary analysis of the CLOVERS trial Crit. Care (IF 8.8) Pub Date : 2024-07-11 Anselm Jorda, Ivor S. Douglas, Thomas Staudinger, Gottfried Heinz, Felix Bergmann, Rainer Oberbauer, Gürkan Sengölge, Markus Zeitlinger, Bernd Jilma, Nathan I. Shapiro, Georg Gelbenegger
Early fluid management in patients with advanced chronic kidney disease (CKD) and sepsis-induced hypotension is challenging with limited evidence to support treatment recommendations. We aimed to compare an early restrictive versus liberal fluid management for sepsis-induced hypotension in patients with advanced CKD. This post-hoc analysis included patients with advanced CKD (eGFR of less than 30 mL/min/1
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A proof of concept for microcirculation monitoring using machine learning based hyperspectral imaging in critically ill patients: a monocentric observational study Crit. Care (IF 8.8) Pub Date : 2024-07-10 Judith Kohnke, Kevin Pattberg, Felix Nensa, Henning Kuhlmann, Thorsten Brenner, Karsten Schmidt, René Hosch, Florian Espeter
Impaired microcirculation is a cornerstone of sepsis development and leads to reduced tissue oxygenation, influenced by fluid and catecholamine administration during treatment. Hyperspectral imaging (HSI) is a non-invasive bedside technology for visualizing physicochemical tissue characteristics. Machine learning (ML) for skin HSI might offer an automated approach for bedside microcirculation assessment
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Considerations regarding the hospital-acquired pressure injuries in paediatric patients J. Adv. Nurs. (IF 3.8) Pub Date : 2024-07-05 Jinhui Huang, Qiong Xi
I am writing to express my appreciation for the insightful study conducted by (Dimanopoulos et al. (2024)), titled ‘Incidence of hospital-acquired pressure injuries and predictors of severity in a paediatric hospital’. This study aimed to identify and describe hospital-acquired pressure injuries (HAPIs) admission incidence and severity predictors in a large Australian children's hospital. The findings
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Unveiling the hidden burden: the impact of undiagnosed comorbidities on health-related quality of life in ICU survivors Crit. Care (IF 8.8) Pub Date : 2024-07-10 Jill Moser, Roos Mensink, Marisa Onrust, Fredrike Blokzijl, Jacqueline Koeze
With great interest we read the recent article by Orwelius et al. [1] on the impact of comorbidities on health-related quality of life (HRQoL) in ICU survivors. We commend the authors for their work on addressing this challenging topic and for providing an insightful review. While we agree with the key issues highlighted by the authors, we believe that several points warrant further discussion. One
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Another perspective on tidal volume: from statistics to uncertainty Intensive Care Med. (IF 27.1) Pub Date : 2024-07-09 Diego Escarramán Martínez, Manuel Alberto Guerrero Gutiérrez, Fernando Jaziel López Pérez, Orlando Rubén Perez Nieto, Antonio de Jesus Granados Martínez
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Physiological and clinical effects of trunk inclination adjustment in patients with respiratory failure: a scoping review and narrative synthesis Crit. Care (IF 8.8) Pub Date : 2024-07-09 Martín H. Benites, Marcelo Zapata-Canivilo, Fabian Poblete, Francisco Labbe, Romina Battiato, Andrés Ferre, Jorge Dreyse, Guillermo Bugedo, Alejandro Bruhn, Eduardo L. V. Costa, Jaime Retamal
Adjusting trunk inclination from a semi-recumbent position to a supine-flat position or vice versa in patients with respiratory failure significantly affects numerous aspects of respiratory physiology including respiratory mechanics, oxygenation, end-expiratory lung volume, and ventilatory efficiency. Despite these observed effects, the current clinical evidence regarding this positioning manoeuvre
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Immune profiling of critically ill patients with acute kidney injury during the first week after various types of injuries: the REALAKI study Crit. Care (IF 8.8) Pub Date : 2024-07-08 Frank Bidar, Louis Peillon, Maxime Bodinier, Fabienne Venet, Guillaume Monneret, Anne-Claire Lukaszewicz, Jean-François Llitjos, Julien Textoris, Thomas Rimmelé
Acute kidney injury (AKI) is common in hospitalized patients and results in significant morbidity and mortality. The objective of the study was to explore the systemic immune response of intensive care unit patients presenting with AKI, especially the association between immune profiles and persistent AKI during the first week after admission following various types of injuries (sepsis, trauma, surgery
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Thiamine supplementation in septic shock patients: still looking for the target population Crit. Care (IF 8.8) Pub Date : 2024-07-08 Amanda Gomes Pereira, Nara A. Costa, Mariana B. de Moraes, Marina P. Okoshi, Leonardo A. M. Zornoff, Paula S. Azevedo, Marcos F. Minicucci, Sérgio A. R. de Paiva, Bertha F. Polegato
In recent years, there has been a growing interest in thiamine as a potential adjunctive therapy in septic shock, given its key role in the maintenance of cellular metabolism and energy production, being involved in various biological processes [1]. It is supposed that treatment of thiamine deficiency could mitigate alterations associated with organ dysfunction and lead to better outcomes in this critical
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Clinical application of targeted next-generation sequencing in severe pneumonia: a retrospective review Crit. Care (IF 8.8) Pub Date : 2024-07-08 Peng Zhang, Baoyi Liu, Shuang Zhang, Xuefei Chang, Lihe Zhang, Dejian Gu, Xin Zheng, Jiaqing Chen, Saiyin Xiao, Zhentao Wu, Xuemin Cai, Mingfa Long, Wenjie Lu, Mingzhu Zheng, Rongrong Chen, Rui Gao, Yan Zheng, Jinhua Wu, Qiujuan Feng, Gang He, Yantang Chen, Weihao Zheng, Wanli Zuo, Yanming Huang, Xin Zhang
The precise identification of the underlying causes of infectious diseases, such as severe pneumonia, is essential, and the development of next-generation sequencing (NGS) has enhanced the effectiveness of pathogen detection. However, there is limited information on the systematic assessment of the clinical use of targeted next-generation sequencing (tNGS) in cases of severe pneumonia. A retrospective
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Diagnostic accuracy of lung ultrasound in diagnosis of ARDS and identification of focal or non-focal ARDS subphenotypes: a systematic review and meta-analysis Crit. Care (IF 8.8) Pub Date : 2024-07-08 Maud M. A. Boumans, William Aerts, Luigi Pisani, Lieuwe D. J. Bos, Marry R. Smit, Pieter R. Tuinman
Acute respiratory distress syndrome (ARDS) is a life-threatening respiratory condition with high mortality rates, accounting for 10% of all intensive care unit admissions. Lung ultrasound (LUS) as diagnostic tool for acute respiratory failure has garnered widespread recognition and was recently incorporated into the updated definitions of ARDS. This raised the hypothesis that LUS is a reliable method