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Scientific consideration of sex and gender is the responsibility of the many, not the few Lancet (IF 98.4) Pub Date : 2024-11-11 Alice Witt, Robyn Norton, Mark Woodward, Kate Womersley
No Abstract
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Mobilising the health community to protect health care from attack Lancet (IF 98.4) Pub Date : 2024-11-11 Martin Chalfie, Leonard Rubenstein, Lujain Alqodmani, Georges C Benjamin, Pamela F Cipriano, Carlos del Rio, Victor J Dzau, Timothy Johnson, Robert S Lawrence, Michele Heisler
No Abstract
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Mexico Summit 20 years on—gains and challenges Lancet (IF 98.4) Pub Date : 2024-11-10 Tikki Pang, Ulysses Panisset, Francisco Becerra-Posada, Julio Frenk
No Abstract
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Betibeglogene autotemcel gene therapy in patients with transfusion-dependent, severe genotype β-thalassaemia (HGB-212): a non-randomised, multicentre, single-arm, open-label, single-dose, phase 3 trial Lancet (IF 98.4) Pub Date : 2024-11-08 Janet L Kwiatkowski, Mark C Walters, Suradej Hongeng, Evangelia Yannaki, Andreas E Kulozik, Joachim B Kunz, Martin G Sauer, Adrian J Thrasher, Isabelle Thuret, Ashutosh Lal, Ge Tao, Shamshad Ali, Himal L Thakar, Heidi Elliot, Ankit Lodaya, Ji Lee, Richard A Colvin, Franco Locatelli, Alexis A Thompson
BackgroundTransfusion-dependent β-thalassaemia (TDT) is a severe disease, resulting in lifelong blood transfusions, iron overload, and associated complications. Betibeglogene autotemcel (beti-cel) gene therapy uses autologous haematopoietic stem and progenitor cells (HSPCs) transduced with BB305 lentiviral vector to enable transfusion independence. MethodsHGB-212 was a non-randomised, multicentre,
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Japan's lonely deaths: a social epidemic Lancet (IF 98.4) Pub Date : 2024-11-08 Megan Tatum
No Abstract
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Identifying groups with the greatest need for interventions to improve wellbeing Lancet (IF 98.4) Pub Date : 2024-11-07 Farah Allouch, Katherine T Mills
No Abstract
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Disparities in wellbeing in the USA by race and ethnicity, age, sex, and location, 2008–21: an analysis using the Human Development Index Lancet (IF 98.4) Pub Date : 2024-11-07 Laura Dwyer-Lindgren, Parkes Kendrick, Mathew M Baumann, Zhuochen Li, Chris Schmidt, Dillon O Sylte, Farah Daoud, Wichada La Motte-Kerr, Robert W Aldridge, Catherine Bisignano, Simon I Hay, Ali H Mokdad, Christopher J L Murray
BackgroundThe Human Development Index (HDI)—a composite metric encompassing a population's life expectancy, education, and income—is used widely for assessing and comparing human development and wellbeing at the country level, but does not account for within-country inequality. In this study of the USA, we aimed to adapt the HDI framework to measure the HDI at an individual level to examine disparities
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Addressing transnational exploitation and armed conflict in the response to mpox Lancet (IF 98.4) Pub Date : 2024-11-07 Jirair Ratevosian, Michele Heisler, Tom Carpino, Thomas McHale, Joyeux Mushekuru, Chris Beyrer
No Abstract
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Opening the door to widespread iPSC-derived regenerative therapy for corneal epithelial opacity Lancet (IF 98.4) Pub Date : 2024-11-07 Yasuhiko Hirami, Michiko Mandai
No Abstract
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Induced pluripotent stem-cell-derived corneal epithelium for transplant surgery: a single-arm, open-label, first-in-human interventional study in Japan Lancet (IF 98.4) Pub Date : 2024-11-07 Takeshi Soma, Yoshinori Oie, Hiroshi Takayanagi, Shoko Matsubara, Tomomi Yamada, Masaki Nomura, Yu Yoshinaga, Kazuichi Maruyama, Atsushi Watanabe, Kayo Takashima, Zaixing Mao, Andrew J Quantock, Ryuhei Hayashi, Kohji Nishida
BackgroundThe loss of corneal epithelial stem cells from the limbus at the edge of the cornea has severe consequences for vision, with the pathological manifestations of a limbal stem-cell deficiency (LSCD) difficult to treat. Here, to the best of our knowledge, we report the world's first use of corneal epithelial cell sheets derived from human induced pluripotent stem cells (iPSCs) to treat LSCD
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Mpox surveillance: the need for enhanced testing and genomic epidemiology Lancet (IF 98.4) Pub Date : 2024-11-07 Jeremy R Wang
No Abstract
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Offline: Being one of the lucky ones Lancet (IF 98.4) Pub Date : 2024-11-07 Richard Horton
No Abstract
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Marina Romanello: tracking climate change and health Lancet (IF 98.4) Pub Date : 2024-11-07 Aarathi Prasad
No Abstract
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A history of hydrotherapy and mental health Lancet (IF 98.4) Pub Date : 2024-11-07 Matthew Smith
No Abstract
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Violence against women and girls in Sudan's conflict zones Lancet (IF 98.4) Pub Date : 2024-11-07 Ibrahim Nagmeldin Hassan
No Abstract
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Sparsentan and kidney protection: improved medullary oxygenation? Lancet (IF 98.4) Pub Date : 2024-11-07 Dion Groothof, Reinold O B Gans, Stephan J L Bakker
No Abstract
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Sparsentan and kidney protection: improved medullary oxygenation? – Authors' reply Lancet (IF 98.4) Pub Date : 2024-11-07 Donald Kohan, Jula Inrig, Brad H Rovin, Radko Komers
No Abstract
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Adjuvant everolimus after renal cell carcinoma nephrectomy Lancet (IF 98.4) Pub Date : 2024-11-07 Yao-Ning Feng, Li Xiao, Guang-Yu Xie
No Abstract
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Adjuvant everolimus after renal cell carcinoma nephrectomy – Authors' reply Lancet (IF 98.4) Pub Date : 2024-11-07 Christopher W Ryan, Catherine M Tangen, Primo N Lara
No Abstract
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Treatment of vulnerable atherosclerotic plaques: the PREVENT trial Lancet (IF 98.4) Pub Date : 2024-11-07 Giuseppe Ferrante, Gianluca Mincione, Antonio Colombo
No Abstract
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Treatment of vulnerable atherosclerotic plaques: the PREVENT trial Lancet (IF 98.4) Pub Date : 2024-11-07 Kyriakos Dimitriadis, Nikolaos Pyrpyris, Konstantinos Tsioufis
No Abstract
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Treatment of vulnerable atherosclerotic plaques: the PREVENT trial Lancet (IF 98.4) Pub Date : 2024-11-07 Chinmay Khandkar, Jordan Fulcher, Sanjay Patel, Anthony Keech
No Abstract
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Treatment of vulnerable atherosclerotic plaques: the PREVENT trial Lancet (IF 98.4) Pub Date : 2024-11-07 Shichu Liang, Junyan Zhang, Zhongxiu Chen, Hua Wang, Yong He
No Abstract
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Treatment of vulnerable atherosclerotic plaques: the PREVENT trial Lancet (IF 98.4) Pub Date : 2024-11-07 Ioannis Merinopoulos, Simon C Eccleshall, Vassilios S Vassiliou
No Abstract
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Treatment of vulnerable atherosclerotic plaques: the PREVENT trial – Authors' reply Lancet (IF 98.4) Pub Date : 2024-11-07 Seung-Jung Park, Jung-Min Ahn, Do-Yoon Kang, Duk-Woo Park
No Abstract
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Department of Error Lancet (IF 98.4) Pub Date : 2024-11-07
Hickey M, Hunter MS, Crandall CJ, et al. Reflections on The Lancet menopause Series. Lancet 2024; 404: 1307–08—In this Correspondence, the order of the author list and Hadine Joffe's name were incorrect. These corrections have been made to the online version as of Nov 7, 2024.
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Intravascular large B-cell lymphoma presenting with non-occlusive mesenteric ischaemia Lancet (IF 98.4) Pub Date : 2024-11-07 Kimihiko Nakamura, Toru Inoue, Atsushi Takada
Section snippets ContributorsWe were all involved in the patient's care. KN conceived the paper and drafted the manuscript. All the authors reviewed, edited, and approved the final manuscript. Written consent for publication was obtained from the patient. Declaration of interestsWe declare no competing interests.
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Learning from long COVID: conceptualising action to tackle infection-associated non-communicable diseases Lancet (IF 98.4) Pub Date : 2024-11-06 Nisreen A Alwan, Ziyad Al-Aly
No Abstract
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Concerns regarding Gaza mortality estimates Lancet (IF 98.4) Pub Date : 2024-11-04 Ruth Oratz, Steven Roth, Joel Zivot, Yael Halaas
No Abstract
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Authors' reply Lancet (IF 98.4) Pub Date : 2024-11-04 Rasha Khatib, Martin McKee, Salim Yusuf
No Abstract
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Concerns regarding Gaza mortality estimates Lancet (IF 98.4) Pub Date : 2024-11-04 Rafael Beyar, Karl Skorecki
No Abstract
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Concerns regarding Gaza mortality estimates Lancet (IF 98.4) Pub Date : 2024-11-04 Andrew Gilbert
No Abstract
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Counting every newborn: liveborn or stillborn Lancet (IF 98.4) Pub Date : 2024-11-04 Hannah Blencowe, Lucia Hug
No Abstract
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Global, regional, and national stillbirths at 20 weeks' gestation or longer in 204 countries and territories, 1990–2021: findings from the Global Burden of Disease Study 2021 Lancet (IF 98.4) Pub Date : 2024-11-04
BackgroundStillbirth is a devastating and often avoidable adverse pregnancy outcome. Monitoring stillbirth levels and trends—in a comprehensive manner that leaves no one uncounted—is imperative for continuing progress in pregnancy loss reduction. This analysis, completed as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021, methodically accounted for different stillbirth
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Bioadaptor implant versus contemporary drug-eluting stent in percutaneous coronary interventions in Sweden (INFINITY-SWEDEHEART): a single-blind, non-inferiority, registry-based, randomised controlled trial Lancet (IF 98.4) Pub Date : 2024-10-28 David Erlinge, Jonas Andersson, Ole Fröbert, Mattias Törnerud, Mehmet Hamid, Thomas Kellerth, Per Grimfjärd, Oscar Winnberg, Juliane Jurga, Henrik Wagner, Sammy Zwackman, Martin Adielsson, Patrik Alström, Elli Masoe, Anders Ulvenstam, Jonas Millgård, Felix Böhm, Claes Held, Henrik Renlund, Jonas Oldgren, Stefan James
BackgroundPersistent non-plateauing adverse event rates in patients who underwent percutaneous coronary intervention (PCI) remain a challenge. A bioadaptor is a novel implant that addresses this issue by restoring the haemodynamic modulation of the artery, allowing cyclic pulsatility, vasomotion, and adaptative remodelling, by unlocking and providing dynamic support to the artery. We aimed to assess
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Striving for balance in decisions on antenatal pharmacotherapy Lancet (IF 98.4) Pub Date : 2024-10-31 Charlotte Koldeweij, Verna AAM Jans, Catriona Waitt, Rick Greupink, Kim LHE Vanden Auweele, Bryony D Franklin, Hubertina CJ Scheepers, Saskia N de Wildt
Most individuals use medication during pregnancy. However, decision making on antenatal pharmacotherapy presents considerable ethical and scientific challenges. Amid a sociocultural paradigm prioritising the elimination of fetal risks, available evidence and guidance are limited, and current decision making on antenatal drugs mostly proceeds in an ad-hoc and, often, biased manner. This approach might
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Coronary stenting with bioadaptors Lancet (IF 98.4) Pub Date : 2024-10-28 Davide Capodanno
No Abstract
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Offline: Asking our eyes to see differently Lancet (IF 98.4) Pub Date : 2024-10-31 Richard Horton
No Abstract
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Magda Robalo: challenging barriers to health Lancet (IF 98.4) Pub Date : 2024-10-31 Aarathi Prasad
No Abstract
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Grief, hope, and courage | Rachel Clarke, The Story of a Heart, Little Brown Group (2024), p. 288, £22·00, ISBN: 9780349145594 Lancet (IF 98.4) Pub Date : 2024-10-31 Gavin Francis
No Abstract
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John Allen Clements Lancet (IF 98.4) Pub Date : 2024-10-31 Geoff Watts
Download: Download high-res image (233KB) Download: Download full-size image
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The Pandemic Fund's inclusivity problem Lancet (IF 98.4) Pub Date : 2024-10-31 Samuel S Han, Kee B Park
No Abstract
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Endovascular thrombectomy for acute ischaemic stroke: the TENSION trial Lancet (IF 98.4) Pub Date : 2024-10-31 Gabriel Broocks, Andre Kemmling
No Abstract
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Endovascular thrombectomy for acute ischaemic stroke: the TENSION trial Lancet (IF 98.4) Pub Date : 2024-10-31 Hong-Jie Jhou, Li-Yu Yang, Po-Huang Chen
No Abstract
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Endovascular thrombectomy for acute ischaemic stroke: the TENSION trial Lancet (IF 98.4) Pub Date : 2024-10-31 Zhenzhen Wang, Kaili Huang, Zhi-Xin Huang
No Abstract
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Endovascular thrombectomy for acute ischaemic stroke: the TENSION trial – Authors' reply Lancet (IF 98.4) Pub Date : 2024-10-31 Götz Thomalla, Susanne Bonekamp, Jens Fiehler, Martin Bendszus
No Abstract
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Department of Error Lancet (IF 98.4) Pub Date : 2024-10-31
The Lancet. The fertility industry: profiting from vulnerability. Lancet 2024; 404: 215—The discussion of the private clinics in this Editorial should have said that PGT is more likely to be part of IVF treatment in a private equity-affiliated clinic than elsewhere. The references have been updated to refer to the original study on this issue. These changes have been made to the online version as of
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Department of Error Lancet (IF 98.4) Pub Date : 2024-10-31
Lorusso D, Xiang Y, Hasegawa K, et al. Pembrolizumab or placebo with chemoradiotherapy followed by pembrolizumab or placebo for newly diagnosed, high-risk, locally advanced cervical cancer (ENGOT-cx11/GOG-3047/KEYNOTE-A18): overall survival results from a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet 2024; 404: 1321–32—The appendix for this Article has been updated as of Oct 31
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Embolic stroke and patent foramen ovale in a 43-year-old fan chanting during a football match Lancet (IF 98.4) Pub Date : 2024-10-31 Marc Etienne Wolf, Elke Roser, Hansjörg Bäzner
Section snippets ContributorsWe all provided care for the patient and acquired and analysed the data. MEW conceived the paper and designed and drafted the manuscript and figures. ER drafted the figures. HB and ER revised the manuscript. Written consent for publication was obtained from the patient. Declaration of interestsWe declare no competing interests.
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Steatotic liver disease Lancet (IF 98.4) Pub Date : 2024-10-31 Mads Israelsen, Sven Francque, Emmanuel A Tsochatzis, Aleksander Krag
Steatotic liver disease is the overarching term for conditions characterised by abnormal lipid accumulation in the liver (liver or hepatic steatosis). Steatotic liver disease encompasses what was previously termed non-alcoholic fatty liver disease (NAFLD), which is now called metabolic dysfunction-associated steatotic liver disease (MASLD). Additionally, steatotic liver disease includes alcohol-related
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Racism and health inequity: a global syndemic for children—the Lancet Commission on racism and child health Lancet (IF 98.4) Pub Date : 2024-10-30 Delan Devakumar, Lu Gram, Sonora English, Thilagawathi Abi Deivanayagam, Mita Huq, Pamela Das
No Abstract
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Pernkopf was not alone: the Nazi origins of the Spalteholz–Spanner atlas Lancet (IF 98.4) Pub Date : 2024-10-30 Claudia Krebs, Katerina Schwab, Manjot Kahlon, Ivica Bratanovic, Aleteia Greenwood, Shelly Rosenblum, Sabine Hildebrandt
No Abstract
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The UK must help end the global tobacco epidemic fuelled by British firms Lancet (IF 98.4) Pub Date : 2024-10-30 Deborah Arnott, J Robert Branston, Jamie Brown, Hazel Cheeseman, Anna B Gilmore
No Abstract