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Global patterns of leukemia by subtype, age, and sex in 185 countries in 2022 Leukemia (IF 12.8) Pub Date : 2024-11-20 Dagrun S. Daltveit, Eileen Morgan, Murielle Colombet, Eva Steliarova-Foucher, Karima Bendahhou, Rafael Marcos-Gragera, Zheng Rongshou, Alexandra Smith, Hui Wei, Isabelle Soerjomataram
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Polycomb group protein Mel18 inhibits hematopoietic stem cell self-renewal through repressing the transcription of self-renewal and proliferation genes Leukemia (IF 12.8) Pub Date : 2024-11-19 Wenjie Cai, Xicheng Liu, Sergio Barajas, Shiyu Xiao, Sasidhar Vemula, Hongxia Chen, Yuxia Yang, Christopher Bochers, Danielle Henley, Sheng Liu, Yuzhi Jia, Michelle Hong, Tiffany M. Mays, Maegan L. Capitano, Huiping Liu, Peng Ji, Zhonghua Gao, Diego Pasini, Jun Wan, Feng Yue, Leonidas C. Platanias, Rongwen Xi, Sisi Chen, Yan Liu
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Graft-versus-host disease after anti-CD19 chimeric antigen receptor T-cell therapy following allogeneic hematopoietic cell transplantation: a transplant complications and paediatric diseases working parties joint EBMT study Leukemia (IF 12.8) Pub Date : 2024-11-19 Guillermo Ortí, Christophe Peczynski, William Boreland, Maeve O’Reilly, Malte von Bonin, Adriana Balduzzi, Caroline Besley, Krzysztof Kalwak, Samppa Ryhänen, Tayfun Güngör, Robert F. Wynn, Peter Bader, Stephan Mielke, Didier Blaise, Persis Amrolia, Ibrahim Yakoub-Agha, Friso Calkoen, Maria-Luisa Schubert, Victoria Potter, Herbert Pichler, Nicolaus Kröger, Mi Kwon, Henrik Sengeloev, Anna Torrent, Yves
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Glucose uptake capacity of leukaemia cells in vitro correlates with response to induction therapy in acute myeloid leukaemia Leukemia (IF 12.8) Pub Date : 2024-11-18 Suqi Deng, Juan Du, Kexiu Huang, Robert Peter Gale, Danqi Pan, Lu Wang, Junjie Wei, Xue Zheng, Ying Xu, Shengqian Xie, Wei Zhou, Weihao Xiao, Bo Liu, Zhiyang Chen, Zhenyu Ju, Hui Zeng
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A phase II trial of ipilimumab, nivolumab, or ipilimumab and nivolumab with or without azacitidine in relapsed or refractory myelodysplastic neoplasms Leukemia (IF 12.8) Pub Date : 2024-11-17 Ian M. Bouligny, Guillermo Montalban-Bravo, Koji Sasaki, Naval Daver, Elias Jabbour, Yesid Alvarado, Courtney D. DiNardo, Farhad Ravandi, Gautam Borthakur, Naveen Pemmaraju, Tapan Kadia, Lucia Masarova, Koichi Takahashi, Michael Andreeff, Alexandre Bazinet, Hui Yang, Rashmi Kanagal, Sherry Pierce, Meghan Meyer, Xuelin Huang, Guillermo Garcia-Manero
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The glycosyltransferase ST3GAL4 drives immune evasion in acute myeloid leukemia by synthesizing ligands for the glyco-immune checkpoint receptor Siglec-9 Leukemia (IF 12.8) Pub Date : 2024-11-17 Vignesh Krishnamoorthy, John Daly, Jimmy Kim, Lidia Piatnitca, Katie A. Yuen, Bhoj Kumar, Mehrnoush Taherzadeh Ghahfarrokhi, Tom Q. T. Bui, Parastoo Azadi, Ly P. Vu, Simon Wisnovsky
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A CADASIL NOTCH3 mutation leads to clonal hematopoiesis and expansion of Dnmt3a-R878H hematopoietic clones Leukemia (IF 12.8) Pub Date : 2024-11-13 Raúl Sánchez-Lanzas, Justin Barclay, Alexandros Hardas, Foteini Kalampalika, Amanda Jiménez-Pompa, Paolo Gallipoli, Miguel Ganuza
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Venetoclax in combination with hypomethylating agents in chronic myelomonocytic leukemia: a propensity score matched multicenter cohort study Leukemia (IF 12.8) Pub Date : 2024-11-12 Douglas Tremblay, Clifford Csizmar, Courtney D. DiNardo, Somedeb Ball, Noa Rippel, Danielle Hammond, Tapan M. Kadia, Farhad Ravandi, Kelly Chien, Grace Van Hyfte, Madhu Mazumdar, Antoine Saliba, Abhishek Mangaonkar, Terra Lasho, Aref Al-Kali, Marina Kremyanskaya, Jonathan Feld, Lewis R. Silverman, Rami Komrokji, John Mascarenhas, Eric Padron, Guillermo Garcia-Manero, David A. Sallman, Mrinal M. Patnaik
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Endothelial heterogeneity in bone marrow: insights across development, adult life and leukemia Leukemia (IF 12.8) Pub Date : 2024-11-11 I. L. Boueya, L. Sandhow, J. R. P. Albuquerque, R. Znaidi, D. Passaro
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Genomic profiling of circulating tumor DNA for childhood cancers Leukemia (IF 12.8) Pub Date : 2024-11-10 Shaohua Lei, Sujuan Jia, Sunitha Takalkar, Ti-Cheng Chang, Xiaotu Ma, Karol Szlachta, Ke Xu, Zhongshan Cheng, Yawei Hui, Selene C. Koo, Paul E. Mead, Qingsong Gao, Priyadarshini Kumar, Colin P. Bailey, Jobin Sunny, Alberto S. Pappo, Sara M. Federico, Giles W. Robinson, Amar Gajjar, Jeffrey E. Rubnitz, Sima Jeha, Ching-Hon Pui, Hiroto Inaba, Gang Wu, Jeffery M. Klco, Ruth G. Tatevossian, Charles G.
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The effect of methylation on the let-7-BCL2L1-BCL2 axis and the potential use of hypomethylating and BH3 mimetic drugs in histiocytic neoplasms Leukemia (IF 12.8) Pub Date : 2024-11-08 Mali Salmon-Divon, Refael Meyuchas, Ofer Shpilberg, Elimelech Okon, Jamal Benhamida, Mariko Yabe, Kseniya Petrova-Drus, Tal Zvida-Bloch, May Basood, Roei Mazor, Benjamin H. Durham, Julien Haroche, Omar Abdel-Wahab, Eli L. Diamond, Oshrat Hershkovitz-Rokah
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Rapid growth of acquired UBA1 mutations predisposes male patients to low-risk MDS Leukemia (IF 12.8) Pub Date : 2024-11-08 Peng Li, F. N. U. Alnoor, Wei Xie, Margaret Williams, Julie Feusier, Yi Ding, Xiangrong Zhao, Gang Zheng, Chen Zhao, Arthur W. Zieske, Youli Zu, Philipp W. Raess, Srinivas Tantravahi, Afaf Osman, Ami B. Patel, Tsewang Tashi, Jay L. Patel, Anna P. Matynia, Madhu P. Menon, Rodney R. Miles, Jeffrey R. Jacobsen, Tracy I. George, Douglas W. Sborov, Philippe Szankasi, Paul Rindler, Devin Close, Robert S
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Genome-first determination of the prevalence and penetrance of eight germline myeloid malignancy predisposition genes: a study of two population-based cohorts Leukemia (IF 12.8) Pub Date : 2024-11-06 Rachel M. Hendricks, Jung Kim, Jeremy S. Haley, Mark Louie Ramos, Uyenlinh L. Mirshahi, David J. Carey, Douglas R. Stewart, Lisa J. McReynolds
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YTHDC1 is a therapeutic target for B-cell acute lymphoblastic leukemia by attenuating DNA damage response through the KMT2C-H3K4me1/me3 epigenetic axis Leukemia (IF 12.8) Pub Date : 2024-11-05 Xinxin Li, Minhua Zheng, Shoubao Ma, Fengze Nie, Zhiqiang Yin, Yanan Liang, Xianchun Yan, Weihong Wen, Jianhua Yu, Yingmin Liang, Siyong Huang, Hua Han
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Pre-emptive therapeutic decisions based on measurable residual disease status in acute myeloid leukemia: ready for prime time? Leukemia (IF 12.8) Pub Date : 2024-11-05 Firas El Chaer, Anthony J. Perissinotti, Sanam Loghavi, Amer M. Zeidan
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Transcriptional regulatory program controlled by MYB in T-cell acute lymphoblastic leukemia Leukemia (IF 12.8) Pub Date : 2024-11-02 Xiaoman Shao, Rui Yokomori, Jolynn Zu Lin Ong, Haoqing Shen, Dennis Kappei, Leilei Chen, Allen Eng Juh Yeoh, Shi Hao Tan, Takaomi Sanda
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Post-transplant cyclophosphamide separates graft-versus host disease and graft versus leukemia effects after HLA-matched stem-cell transplantation for acute myeloid leukemia Leukemia (IF 12.8) Pub Date : 2024-10-31 Avichai Shimoni, Christophe Peczynski, Myriam Labopin, Alexander Kulagin, Ellen Meijer, Jan Cornelissen, Goda Choi, Jaime Sanz, Montserrat Rovira, Gwendolyn Van Gorkom, Nicolaus Kröger, Yener Koc, Jan Vydra, J. L. Diez-Martin, Carlos Solano, Amit Patel, Patrizia Chiusolo, Fabio Ciceri, Arnon Nagler, Mohamad Mohty
The association of graft-versus-host disease (GVHD) and graft-versus-leukemia (GVL) effects after allogeneic stem-cell transplantation (SCT) is well-established but was not confirmed in the modern era and following post-transplant cyclophosphamide (PTCy). We assessed GVHD/ GVL association in AML patients following HLA-matched SCT with standard calcineurin-based (n = 12,653, 57% with additional in-vivo
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The dynamic evolution of lineage switch under CD19 CAR-T treatment in non-KMT2A rearranged B-ALL patients Leukemia (IF 12.8) Pub Date : 2024-10-31 Shaowei Qiu, Yihan Mei, Runxia Gu, Yu Liu, Manling Chen, Haiyan Xing, Kejing Tang, Zheng Tian, Qing Rao, Donglin Yang, Aiming Pang, Shuning Wei, Yujiao Jia, Huijun Wang, Sizhou Feng, Hui Wei, Ping Zhu, Min Wang, Ying Wang, Wenbing Liu, Jianxiang Wang
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Comparative small molecule screening of primary human acute leukemias, engineered human leukemia and leukemia cell lines Leukemia (IF 12.8) Pub Date : 2024-10-29 Safia Safa-Tahar-Henni, Karla Páez Martinez, Verena Gress, Nayeli Esparza, Élodie Roques, Florence Bonnet-Magnaval, Mélanie Bilodeau, Valérie Gagné, Eva Bresson, Sophie Cardin, Nehme El-Hachem, Isabella Iasenza, Gabriel Alzial, Isabel Boivin, Naoto Nakamichi, Anne-Cécile Soufflet, Cristina Mirela Pascariu, Jean Duchaine, Simon Mathien, Éric Bonneil, Kolja Eppert, Anne Marinier, Guy Sauvageau, Geneviève
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Validation and refinement of the 2022 European LeukaemiaNet genetic risk classification of acute myeloid leukaemia patients receiving allogeneic haematopoietic cell transplantation Leukemia (IF 12.8) Pub Date : 2024-10-28 Weihao Chen, Lieguang Chen, Yang Cao, Chuanhe Jiang, Yi Luo, Guifang Ouyang, Jian Yu, Yamin Tan, Xiaoyu Lai, Lizhen Liu, Huarui Fu, Yishan Ye, Luxin Yang, Congxiao Zhang, Jimin Shi, Xiaoxia Hu, He Huang, Yanmin Zhao
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Aberrant BCAT1 expression augments MTOR activity and accelerates disease progression in chronic lymphocytic leukemia Leukemia (IF 12.8) Pub Date : 2024-10-25 Qiangqiang Shao, Jedrzej Wykretowicz, Nan Hu, Karan Bedi, Mohamed Rizk, Isabella A. Malek, Surinder Kumar, David B. Lombard, Kerby Shedden, David Scott, Sami N. Malek
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Antibody blockade of the PSGL-1 immune checkpoint enhances T-cell responses to B-cell lymphoma Leukemia (IF 12.8) Pub Date : 2024-10-25 João L. Pereira, Liliana Arede, Francisca Ferreira, Andreia Matos, Dulcineia Pereira, Rita F. Santos, Alexandre M. Carmo, Maria J. Oliveira, José C. Machado, Delfim Duarte, Nuno R. dos Santos
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Leveraging CRISPR gene editing technology to optimize the efficacy, safety and accessibility of CAR T-cell therapy Leukemia (IF 12.8) Pub Date : 2024-10-25 Tao Lei, Yazhuo Wang, Yuchen Zhang, Yufei Yang, Jiaying Cao, Jiansong Huang, Jiali Chen, Huajing Chen, Jiayi Zhang, Luzheng Wang, Xinjie Xu, Robert Peter Gale, Liang Wang
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Apoliprotein E-mediated ferroptosis controls cellular proliferation in chronic lymphocytic leukemia Leukemia (IF 12.8) Pub Date : 2024-10-23 Federica Nardi, Rosita Del Prete, Roberta Drago, Anthea Di Rita, Francesco Edoardo Vallone, Sara Ciofini, Margherita Malchiodi, Laura Pezzella, Laura Tinti, Vittoria Cicaloni, Laura Salvini, Danilo Licastro, Aidan T. Pezacki, Christopher J. Chang, Giuseppe Marotta, Antonella Naldini, Silvia Deaglio, Tiziana Vaisitti, Alessandro Gozzetti, Monica Bocchia, Anna Kabanova
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NPM1-fusion proteins promote myeloid leukemogenesis through XPO1-dependent HOX activation Leukemia (IF 12.8) Pub Date : 2024-10-23 Yuko Shimosato, Keita Yamamoto, Yuhan Jia, Wenyu Zhang, Norio Shiba, Yasuhide Hayashi, Shuichi Ito, Toshio Kitamura, Susumu Goyama
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MSI2 mediates WNT/β-Catenin pathway function in hematopoietic stem cells Leukemia (IF 12.8) Pub Date : 2024-10-22 Huifang Zhang, Ruixue Guo, Zhenfen Li, Rui Ma, Shina Xu, Le Yin, Hongkai Zhu, Zineng Huang, Cheng Xing, Yunlong Yang, Yulin Pu, Zhao Cheng, Jing Liu, Hongling Peng, Yue Sheng
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The BIM deletion polymorphism potentiates the survival of leukemia stem and progenitor cells and impairs response to targeted therapies Leukemia (IF 12.8) Pub Date : 2024-10-22 Mengge Yu, Giselle Sek Suan Nah, Vaidehi Krishnan, Fatin Nasha Bte Sulaimi, King Pan Ng, Chuqi Wang, Shruti Bhatt, Charles Chuah, David E. Bergstrom, S. Tiong Ong
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Robust anti-myeloma effect of TAS0612, an RSK/AKT/S6K inhibitor, with venetoclax regardless of cytogenetic abnormalities Leukemia (IF 12.8) Pub Date : 2024-10-22 Haruya Okamoto, Shinsuke Mizutani, Taku Tsukamoto, Yoko Katsuragawa-Taminishi, Yuka Kawaji-Kanayama, Kentaro Mizuhara, Ayako Muramatsu, Reiko Isa, Takahiro Fujino, Yuji Shimura, Koji Ichikawa, Junya Kuroda
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Genome-wide CRISPR screen identifies MAD2L1BP and ANAPC15 as targets for brentuximab vedotin sensitivity in CD30+ peripheral T-cell lymphoma Leukemia (IF 12.8) Pub Date : 2024-10-21 Keito Suto, Norio Takei, Keito Yokoyama, Masahiro Chiba, Takashi Ishio, Michiyuki Maeda, Hideki Goto, Tomoyuki Endo, Takanori Teshima, Yibin Yang, Masao Nakagawa
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Single-cell transcriptomics of pediatric Burkitt lymphoma reveals intra-tumor heterogeneity and markers of therapy resistance Leukemia (IF 12.8) Pub Date : 2024-10-18 Clarissa Corinaldesi, Antony B. Holmes, Gaia Martire, Anna Tosato, Domenico Rizzato, Federica Lovisa, Ilaria Gallingani, Qiong Shen, Lavinia Ferrone, Marian Harris, Kimberly Davies, Luca Molinaro, Umberto Mortara, Angelo Paolo Dei Tos, Kenneth Ofori, Emanuele S. G. D’Amore, Roberto Chiarle, Bo Ngan, Elisa Carraro, Marta Pillon, Shafinaz Hussein, Govind Bhagat, Marco Pizzi, Lara Mussolin, Katia Basso
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CD36 cell surface expression as a surrogate marker to identify ABL/JAK-class kinase fusions in pediatric BCP-ALL Leukemia (IF 12.8) Pub Date : 2024-10-17 Marion Strullu, Aurélie Caye-Eude, Elie Robert, Jean-Marie Renard, Amandine Chaye, Julie Galimand, Odile Fenneteau, Chloé Arfeuille, Wendy Cuccuini, Alexandre Theron, Sandrine Thouvenin, Catherine Paillard, Arnaud Petit, Pierre-Simon Rohrlich, Hélène Cavé, André Baruchel, Elodie Lainey
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Anagrelide and idarubicin combination induces GSDME-mediated pyroptosis as a potential therapy for high-PDE3A acute myeloid leukemia Leukemia (IF 12.8) Pub Date : 2024-10-15 Chenwei Yang, Yixin Hu, Li Gao, Zhiheng Li, Yongping Zhang, Ran Zhuo, Yayun Du, Hu Liu, Qi Ji, Minyuan Liu, Jian Pan, Jun Lu, Peifang Xiao, Yuanyuan Tian, Sudan He, Jing Ling, Shaoyan Hu
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Functional variant rs9344 at 11q13.3 regulates CCND1 expression in multiple myeloma with t(11;14) Leukemia (IF 12.8) Pub Date : 2024-10-14 Hongwei Tang, Huihuang Yan, Suganti Shivaram, Stacey Lehman, Neeraj Sharma, James Smadbeck, Cinthya Zepeda-Mendoza, Shulan Tian, Yan Asmann, Celine Vachon, Alexandre Gaspar Maia, Jonathan Keats, P. Leif Bergsagel, Rafael Fonseca, A. Keith Stewart, Joel-Sean Hsu, Richard K. Kandasamy, Akhilesh Pandey, Marcella A. Kaddoura, Francesco Maura, Amit Mitra, S. Vincent Rajkumar, Shaji K. Kumar, Eran Elhaik
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Acute myeloid leukemia: does sex matter? Leukemia (IF 12.8) Pub Date : 2024-10-14 Jesse M Tettero,Jacqueline Cloos,Lars Bullinger
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Offering patients a second chance: what is the minimum cure rate needed to justify allogeneic hematopoietic cell transplantation? Leukemia (IF 12.8) Pub Date : 2024-10-09 Frederick R. Appelbaum
This invited commentary contains original material that has not been published or submitted elsewhere. Contributions were made by a single author. I have no conflict of interests involving the subject or material.
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ELC52: a novel megakaryocytic leukemia cell line with a CALR type 1 mutation Leukemia (IF 12.8) Pub Date : 2024-10-08 Yukiya Yamamoto, Sachiko Iba, Yoko Inaguma, Akinao Okamoto, Akihiro Abe
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Childhood and adolescent essential thrombocythemia and prefibrotic primary myelofibrosis: insights into diagnosis, outcomes, and treatment from a large Chinese cohort Leukemia (IF 12.8) Pub Date : 2024-10-08 Rongfeng Fu, Huan Dong, Wenjing Gu, Ke Meng, Ting Sun, Xiaofan Liu, Xinmiao Qu, Jia Chen, Feng Xue, Wei Liu, Yunfei Chen, Mankai Ju, Xinyue Dai, Ying Chi, Wentian Wang, Xiaolei Pei, Xiaofan Zhu, Renchi Yang, Huiyuan Li, Lei Zhang
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Disparities in incidence and mortality of pediatric acute lymphoblastic leukemia across countries with different incomes Leukemia (IF 12.8) Pub Date : 2024-10-04 Nan Zhang, Diguang Wen, Teng Wang, Jianchuan Deng
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Synergistic effect of concurrent high molecular risk mutations and lower JAK2 mutant variant allele frequencies on prognosis in patients with myelofibrosis—insights from a multicenter study Leukemia (IF 12.8) Pub Date : 2024-10-04 Yu-Hung Wang, Chao-Hung Wei, Chien-Chin Lin, Carmelo Gurnari, Hussein Awada, Lina Benajiba, Rafael Daltro de Oliveira, Juliette Soret-Dulphy, Bruno Cassinat, Andrius Zucenka, Adrián Mosquera Orgueira, Chang-Tsu Yuan, Sze-Hwei Lee, Chi-Yuan Yao, Kristian Gurashi, Hsin-An Hou, Kiran Batta, Manuel Mateo Pérez Encinas, Wen-Chien Chou, Jaroslaw P. Maciejewski, Daniel H. Wiseman, Jean-Jacques Kiladjian,
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Rapid increase of C/EBPα p42 induces growth arrest of acute myeloid leukemia (AML) cells by Cop1 deletion in Trib1-expressing AML Leukemia (IF 12.8) Pub Date : 2024-10-04 Yoshitaka Sunami, Seiko Yoshino, Yukari Yamazaki, Takashi Iwamoto, Takuro Nakamura
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Monitoring clonal burden as an alternative to blast count for myelodysplastic neoplasm treatment response Leukemia (IF 12.8) Pub Date : 2024-10-04 Meagan A. Jacoby, Eric D. Duncavage, Ajay Khanna, Gue Su Chang, Sridhar Nonavinkere Srivatsan, Christopher A. Miller, Feng Gao, Josh Robinson, Jin Shao, Robert S. Fulton, Catrina C. Fronick, Michelle O’Laughlin, Sharon E. Heath, Kimberly Brendel, Monique Chavez, John F. DiPersio, Camille N. Abboud, Keith Stockerl-Goldstein, Peter Westervelt, Amanda Cashen, Iskra Pusic, Stephen T. Oh, John S. Welch
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Cellular taxonomy of the preleukemic bone marrow niche of acute myeloid leukemia Leukemia (IF 12.8) Pub Date : 2024-10-02 Chinmayee Goda, Rohan Kulkarni, Yaphet Bustos, Wenjun Li, Alexander Rudich, Ozlen Balcioglu, Sadie Chidester, Amog P. Urs, Malith Karunasiri, Yzen Al-Marrawi, Erin Korn, Sanjay Kanna, Elizabeth A. R. Garfinkle, Nisarg Shah, Ashley Wooten, Bethany Mundy-Bosse, Lalit Sehgal, Bin Zhang, Guido Marcucci, Elaine R. Mardis, Ramiro Garzon, Robert L. Bowman, Aaron D. Viny, Linde A. Miles, Katherine E. Miller
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The epigenetic state of the cell of origin defines mechanisms of leukemogenesis Leukemia (IF 12.8) Pub Date : 2024-10-01 Zhiheng Li, Sara Fierstein, Mayuri Tanaka-Yano, Katie Frenis, Chun-Chin Chen, Dahai Wang, Marcelo Falchetti, Parker Côté, Christina Curran, Kate Lu, Tianxin Liu, Stuart Orkin, Hojun Li, Edroaldo Lummertz da Rocha, Shaoyan Hu, Qian Zhu, R. Grant Rowe
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Managing the unmanageable: evidence-driven approaches to real-world patient prototypes of TP53-mutant myelodysplastic neoplasms and acute myeloid leukemia Leukemia (IF 12.8) Pub Date : 2024-09-30 Shyam A. Patel
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Characterization of myeloproliferative neoplasms based on genetics only and prognostication of transformation to blast phase Leukemia (IF 12.8) Pub Date : 2024-09-28 Wencke Walter, Niroshan Nadarajah, Stephan Hutter, Heiko Müller, Claudia Haferlach, Wolfgang Kern, Torsten Haferlach, Manja Meggendorfer
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Prognostic value of response to first-line hydroxyurea according to IPSET stratification in essential thrombocythemia Leukemia (IF 12.8) Pub Date : 2024-09-27 Marta Santaliestra, Marta Garrote, María Soledad Noya, Manuel Pérez-Encinas, Alicia Senín, Raúl Pérez-López, Francisca Ferrer-Marín, Gonzalo Carreño-Tarragona, Gonzalo Caballero, Elena Magro, Patricia Vélez, Miguel Ángel Cortés Vázquez, Ana Moretó, Anna Angona, Irene Pastor-Galán, José María Guerra, Carmen García Hernández, María Isabel Mata, Ruth Stuckey, María Teresa Gómez-Casares, Laura Fox, Beatriz
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Essential role of Dhx16-mediated ribosome assembly in maintenance of hematopoietic stem cells Leukemia (IF 12.8) Pub Date : 2024-09-27 Zhigang Li, Jiankun Fan, Yalan Xiao, Wei Wang, Changlin Zhen, Junbing Pan, Weiru Wu, Yuanyuan Liu, Zhe Chen, Qinrong Yan, Hanqing Zeng, Shuyu Luo, Lun Liu, Zhanhan Tu, Xueya Zhao, Yu Hou
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New criteria for estimating numbers of CD34-positive cells in a graft needed for posttransplant bone marrow recovery Leukemia (IF 12.8) Pub Date : 2024-09-25 Yahui Feng, Saibing Qi, Yu Hu, Wen Yan, Yanping Ji, Mingyang Wang, Xiaowen Gong, Qiujin Shen, Wei Zhang, Huilan Liu, Xianjing Zhang, Mengyun Chen, Erling Chen, Xiaolin Zhai, Yi He, Donglin Yang, Aiming Pang, Mingzhe Han, Robert Peter Gale, Zimin Sun, Erlie Jiang, Junren Chen
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Pola-R-CHP or R-CHOEP for first-line therapy of younger patients with high-risk diffuse large B-cell lymphoma: a retrospective comparison of two randomized phase 3 trials Leukemia (IF 12.8) Pub Date : 2024-09-25 Georg Lenz, Hervé Tilly, Marita Ziepert, Bettina Altmann, Charles Herbaux, Fabian Frontzek, Maike Nickelsen, Calvin Lee, Jamie Hirata, Deniz Sahin, Saibah Chohan, Connie Lee Batlevi, Mark Yan, Franck Morschhauser, Norbert Schmitz
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Longitudinal follow up of a phase 2 trial of venetoclax added to hyper-CVAD, nelarabine and pegylated asparaginase in patients with T-cell acute lymphoblastic leukemia and lymphoma Leukemia (IF 12.8) Pub Date : 2024-09-25 Farhad Ravandi, Jayastu Senapati, Nitin Jain, Nicholas J. Short, Tapan Kadia, Gautam Borthakur, Marina Konopleva, William Wierda, Xuelin Huang, Abhishek Maiti, Ghayas Issa, Hayley Balkin, Rebecca Garris, Alessandra Ferrajoli, Guillermo Garcia-Manero, Yesid Alvarado, Partow Kebriaei, Elias Jabbour, Hagop M. Kantarjian
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MERTK inhibition selectively activates a DC – T-cell axis to provide anti-leukemia immunity Leukemia (IF 12.8) Pub Date : 2024-09-25 Justus M. Huelse, Swati S. Bhasin, Kristen M. Jacobsen, Juhye Yim, Beena E. Thomas, Gianna M. Branella, Mojtaba Bakhtiari, Madison L. Chimenti, Travon A. Baxter, Sunil S. Raikar, Xiaodong Wang, Stephen V. Frye, Curtis J. Henry, H. Shelton Earp, Manoj Bhasin, Deborah DeRyckere, Douglas K. Graham
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Epcoritamab in relapsed/refractory large B-cell lymphoma: 2-year follow-up from the pivotal EPCORE NHL-1 trial Leukemia (IF 12.8) Pub Date : 2024-09-25 Catherine Thieblemont, Yasmin H. Karimi, Herve Ghesquieres, Chan Y. Cheah, Michael Roost Clausen, David Cunningham, Wojciech Jurczak, Young Rok Do, Robin Gasiorowski, David John Lewis, Tae Min Kim, Marjolein van der Poel, Michelle Limei Poon, Tatyana Feldman, Kim M. Linton, Anna Sureda, Martin Hutchings, Minh H. Dinh, Nurgul Kilavuz, David Soong, Thomas Mark, Mariana Sacchi, Tycel Phillips, Pieternella
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LocoMMotion: a study of real-life current standards of care in triple-class exposed patients with relapsed/refractory multiple myeloma – 2-year follow-up (final analysis) Leukemia (IF 12.8) Pub Date : 2024-09-25 María-Victoria Mateos, Katja Weisel, Valerio De Stefano, Hartmut Goldschmidt, Michel Delforge, Mohamad Mohty, Dominik Dytfeld, Emanuele Angelucci, Laure Vincent, Aurore Perrot, Reuben Benjamin, Niels W. C. J. van de Donk, Enrique M. Ocio, Tito Roccia, Jordan M. Schecter, Silva Koskinen, Imène Haddad, Vadim Strulev, Lada Mitchell, Jozefien Buyze, Octavio Costa Filho, Hermann Einsele, Philippe Moreau
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PVR (CD155) epigenetic status mediates immunotherapy response in multiple myeloma Leukemia (IF 12.8) Pub Date : 2024-09-24 Laura Martinez-Verbo, Yoana Veselinova, Pere Llinàs-Arias, Carlos A. García-Prieto, Aleix Noguera-Castells, Miguel L. Pato, Alberto Bueno-Costa, Ignacio Campillo-Marcos, Lorea Villanueva, Aina Oliver-Caldes, Oriol Cardus, Sergi V. Salsench, Almudena García-Ortiz, Antonio Valeri, Elizabeta A. Rojas, Naroa Barrena, Norma C. Gutiérrez, Felipe Prósper, Xabier Agirre, Carlos Fernández de Larrea, Joaquín
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Characterisation and prognostic impact Of ZRSR2 mutations in myeloid neoplasms Leukemia (IF 12.8) Pub Date : 2024-09-23 Mahmoud Yacout, Bahga Katamesh, Yazan Jabban, Rong He, David Viswanatha, Dragan Jevremovic, Patricia Greipp, Kurt Bessonen, Jeanne Palmer, James Foran, Antoine Saliba, Mehrdad Hefazi-Torghabeh, Kebede Begna, William Hogan, Mrinal Patnaik, Mithun Shah, Hassan Alkhateeb, Aref Al-Kali
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Is ibrutinib-related atrial fibrillation dose dependent? Insights from an individual case level analysis of the World Health Organization pharmacovigilance database Leukemia (IF 12.8) Pub Date : 2024-09-19 Joachim Alexandre, Jonaz Font, Da-Silva Angélique, Baptiste Delapierre, Ghandi Damaj, Anne-Flore Plane, Damien Legallois, Paul Milliez, Charles Dolladille, Basile Chrétien
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Efficient combinatorial adaptor-mediated targeting of acute myeloid leukemia with CAR T-cells Leukemia (IF 12.8) Pub Date : 2024-09-18 Laura Volta, Renier Myburgh, Christian Pellegrino, Christian Koch, Monique Maurer, Francesco Manfredi, Mara Hofstetter, Anne Kaiser, Florin Schneiter, Jan Müller, Marco M. Buehler, Roberto De Luca, Nicholas Favalli, Chiara F. Magnani, Timm Schroeder, Dario Neri, Markus G. Manz
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Selective degradation of mutant FMS-like tyrosine kinase-3 requires BIM-dependent depletion of heat shock proteins Leukemia (IF 12.8) Pub Date : 2024-09-17 Melisa Halilovic, Mohamed Abdelsalam, Joanna Zabkiewicz, Michelle Lazenby, Caroline Alvares, Matthias Schmidt, Walburgis Brenner, Sara Najafi, Ina Oehme, Christoph Hieber, Yanira Zeyn, Matthias Bros, Wolfgang Sippl, Oliver H. Krämer
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Impact of BCR::ABL1 single nucleotide variants on asciminib efficacy Leukemia (IF 12.8) Pub Date : 2024-09-17 Andrew J. Innes, Chloe Hayden, Victoria Orovboni, Simone Claudiani, Fiona Fernando, Afzal Khan, David Rees, Jennifer Byrne, Paolo Gallipoli, Sebastian Francis, Mhairi Copland, Gillian Horne, Manoj Raghavan, Claire Arnold, Angela Collins, Tanya Cranfield, Nicholas Cunningham, Akila Danga, Peter Forsyth, Rebecca Frewin, Paula Garland, Guy Hannah, Daniele Avenoso, Sandra Hassan, Brian J. P. Huntly, Jissan