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Genetic susceptibility of diffuse large B-cell lymphoma: a meta genome-wide association study in Asian population Leukemia (IF 12.8) Pub Date : 2024-12-20 Qian Cui, Wen Tan, Bao Song, Rou-Jun Peng, Ling Wang, Rajkumar Dorajoo, Kok Pin Ng, Guo-Wang Lin, Wing-Yan Au, Raymond H. S. Liang, Chiea Chuen Khor, Qing-Ling Zhang, Jia Nee FOO, Sheng-Ping Li, Fu-Ren Zhang, Xue-Jun Zhang, Xue-Qing Yu, Qing Lan, Stephen Chanock, Wei-Hua Jia, Soon Thye Lim, Wen-Yu Li, Nathaniel Rothman, Jin-Xin Bei, Jie Liu, Dongxin Lin, Jian-Jun Liu
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PAX5::AUTS2 childhood B-ALL: a relapse-prone genetic subtype with frequent central nervous system involvement and a poor outcome Leukemia (IF 12.8) Pub Date : 2024-12-19 Aurélie Caye-Eude, Grazia Fazio, Agata Pastorczak, Judith M. Boer, Doris Steinemann, Debdutta Ganguli, Edwin Sonneveld, Sabrina Haslinger, Lucía D’Andrea, Jutta Bradtke, Bruno A. Lopes, Marketa Zaliova, Gabriele Escherich, Margit König, Klaus Fortschegger, Andrea Inthal, Irina Stasevich, Mariana Emerenciano, Jan Trka, Luis Castillo, Mayur Parihar, Anthony V. Moorman, Anke K. Bergmann, Monique L. den
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ADAR1 is required for acute myeloid leukemia cell survival by modulating post-transcriptional Wnt signaling through impairing miRNA biogenesis Leukemia (IF 12.8) Pub Date : 2024-12-19 Zhongrui Shi, Jiaxing Li, Jiayu Ding, Yiwen Zhang, Wenjian Min, Yasheng Zhu, Yi Hou, Kai Yuan, Chengliang Sun, Xuejiao Wang, Hao Shen, Liping Wang, Shun-Qing Liang, Wenbin Kuang, Xiao Wang, Peng Yang
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Functions of the native NPM1 protein and its leukemic mutant Leukemia (IF 12.8) Pub Date : 2024-12-17 Brunangelo Falini, Daniele Sorcini, Vincenzo Maria Perriello, Paolo Sportoletti
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T-cell diversity and exclusion of blood-derived T-cells in the tumor microenvironment of classical Hodgkin Lymphoma Leukemia (IF 12.8) Pub Date : 2024-12-17 Nicole Seifert, Sarah Reinke, Johanna Grund, Berit Müller-Meinhard, Julia Richter, Thorsten Heilmann, Hans Schlößer, Michaela Kotrova, Monika Brüggemann, Peter Borchmann, Paul J. Bröckelmann, Michael Altenbuchinger, Wolfram Klapper
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Immunoglobulin light chain mutational status refines IGHV prognostic value in identifying chronic lymphocytic leukemia patients with early treatment requirement Leukemia (IF 12.8) Pub Date : 2024-12-17 Jana Nabki, Bashar Al Deeban, Abel Mehari Sium, Chiara Cosentino, Mohammad Almasri, Bassel Awikeh, Nawar Maher, Matteo Bellia, Riccardo Dondolin, Samir Mouhssine, Donatella Talotta, Eleonora Secomandi, Sreekar Kogila, Joseph Ghanej, Francesca Maiellaro, Luca Cividini, Silvia Rasi, Annalisa Chiarenza, Jacopo Olivieri, Massimo Gentile, Francesco Zaja, Maria Ilaria Del Principe, Luca Laurenti, Riccardo
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Capillary leak phenotype as a major cause of death in patients with POEMS syndrome Leukemia (IF 12.8) Pub Date : 2024-12-16 Kenzie Lee, Taxiarchis Kourelis, Marcella Tschautscher, Rahma Warsame, Francis Buadi, Morie Gertz, Eli Muchtar, David Dingli, Suzanne Hayman, Ronald Go, Lisa Hwa, Amie Fonder, Wilson Gonsalves, Miriam Hobbs, Robert Kyle, Prashant Kapoor, Nelson Leung, Moritz Binder, Joselle Cook, Yi Lin, Michelle Rogers, S. Vincent Rajkumar, Shaji Kumar, Angela Dispenzieri
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Co-targeting of the thymic stromal lymphopoietin receptor to decrease immunotherapeutic resistance in CRLF2-rearranged Ph-like and Down syndrome acute lymphoblastic leukemia Leukemia (IF 12.8) Pub Date : 2024-12-16 Tommaso Balestra, Lisa M Niswander, Asen Bagashev, Joseph P Loftus, Savannah L Ross, Robert K Chen, Samantha M McClellan, Jacob J Junco, Diego A Bárcenas López, Karen R. Rabin, Terry J Fry, Sarah K Tasian
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Relationship between donor source, pre-transplant measurable residual disease, and outcome after allografting for adults with acute myeloid leukemia Leukemia (IF 12.8) Pub Date : 2024-12-12 Corentin Orvain, Filippo Milano, Eduardo Rodríguez-Arbolí, Megan Othus, Effie W. Petersdorf, Brenda M. Sandmaier, Frederick R. Appelbaum, Roland B. Walter
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Mpox in people with haematological cancers. Leukemia (IF 12.8) Pub Date : 2024-12-13 R P Gale,A Hochhaus
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Growth retardation and adult height in pediatric patients with chronic-phase chronic myeloid leukemia treated with tyrosine kinase inhibitors Leukemia (IF 12.8) Pub Date : 2024-12-12 Haruko Shima, Chikako Tono, Akihiko Tanizawa, Masaki Ito, Akihiro Watanabe, Yuki Yuza, Kazuko Hamamoto, Hideki Muramatsu, Masahiko Okada, Shoji Saito, Hiroaki Goto, Masaru Imamura, Akiko M. Saito, Souichi Adachi, Eiichi Ishii, Hiroyuki Shimada
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Acute myeloid leukemia associated RUNX1 variants induce aberrant expression of transcription factor TCF4 Leukemia (IF 12.8) Pub Date : 2024-12-12 Mylène Gerritsen, Florentien E. M. in ’t Hout, Ruth Knops, Bas L. R. Mandos, Melanie Decker, Tim Ripperger, Bert A. van der Reijden, Joost H. A. Martens, Joop H. Jansen
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Prognostic relevance of treatment deviations in children with relapsed acute lymphoblastic leukemia who were treated in the ALL-REZ BFM 2002 study Leukemia (IF 12.8) Pub Date : 2024-12-11 Eleni A. Argyriadi, Ingo G. Steffen, Christiane Chen-Santel, Andrej Lissat, Andishe Attarbaschi, Jean-Pierre Bourquin, Guenter Henze, Arend von Stackelberg
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Incidence of Richter transformation of chronic lymphocytic leukemia/small lymphocytic lymphoma in the targeted therapy era Leukemia (IF 12.8) Pub Date : 2024-12-10 Paul J. Hampel, Kari G. Rabe, Yucai Wang, Steven R. Hwang, Saad S. Kenderian, Eli Muchtar, Jose F. Leis, Amber B. Koehler, Mazie Tsang, Talal Hilal, Ricardo Parrondo, Rachel J. Bailen, Susan M. Schwager, Curtis A. Hanson, Esteban Braggio, Susan L. Slager, Min Shi, Cinthya J. Zepeda-Mendoza, Daniel L. Van Dyke, Tait D. Shanafelt, Rebecca L. King, Timothy G. Call, Neil E. Kay, Wei Ding, Sameer A. Parikh
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Allogeneic hematopoietic stem cell transplantation in adult acute myeloid leukemia with t(16;21)(p11;q22)/FUS::ERG Leukemia (IF 12.8) Pub Date : 2024-12-10 Satoshi Mitsuyuki, Yoshimitsu Shimomura, Hiroki Mizumaki, Masamitsu Yanada, Shohei Mizuno, Naoyuki Uchida, Noriko Doki, Ayumu Ito, Masatsugu Tanaka, Tetsuya Nishida, Yuta Katayama, Satoshi Yoshihara, Tetsuya Eto, Satoru Takada, Shuichi Ota, Masako Toyosaki, Yuta Hasegawa, Hirohisa Nakamae, Koji Kawamura, Makoto Onizuka, Takahiro Fukuda, Marie Ohbiki, Yoshiko Atsuta, Takaaki Konuma
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Surrogate endpoints in mature B-cell neoplasms – meaningful or misleading? Leukemia (IF 12.8) Pub Date : 2024-12-10 Florian Simon, Othman Al-Sawaf, John F. Seymour, Barbara Eichhorst
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Is there really an accelerated phase of chronic myeloid leukaemia at presentation? Leukemia (IF 12.8) Pub Date : 2024-12-04 Sen Yang, Xiaoshuai Zhang, Robert Peter Gale, Xiaojun Huang, Qian Jiang
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HMX3 is a critical vulnerability in MECOM-negative KMT2A::MLLT3 acute myelomonocytic leukemia Leukemia (IF 12.8) Pub Date : 2024-12-04 Saioa Arza-Apalategi, Branco M. H. Heuts, Saskia M. Bergevoet, Roos Meering, Daan Gilissen, Pascal W. T. C. Jansen, Anja Krippner-Heidenreich, Peter J. M. Valk, Michiel Vermeulen, Olaf Heidenreich, Torsten Haferlach, Joop H. Jansen, Joost H. A. Martens, Bert A. van der Reijden
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Spatial transcriptomic approaches for characterising the bone marrow landscape: pitfalls and potential Leukemia (IF 12.8) Pub Date : 2024-11-28 Rosalin A. Cooper, Emily Thomas, Anna M. Sozanska, Carlo Pescia, Daniel J. Royston
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Infection-related pathway activation and vulnerability to arsenic trioxide in acute promyelocytic leukemia with TTMV::RARA Leukemia (IF 12.8) Pub Date : 2024-11-28 Jiacheng Lou, Yi Zhang, Jingfen Tao, Wen Jin, Yongmei Zhu, Zhuo Wang, Min Wu, Hongmei Yi, Xiaoxiao Chen, Shuhong Shen, Junmin Li, Zhu Chen, Saijuan Chen, Yangyang Xie, Li Chen, Kankan Wang
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Relevance of blast counts for genetic subclassification in MDS Leukemia (IF 12.8) Pub Date : 2024-11-27 Sandra Huber, Torsten Haferlach, Stephan Hutter, Gregor Hoermann, Wolfgang Kern, Claudia Haferlach
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Comprehensive genomic analysis reveals molecular heterogeneity in pediatric ALK-positive anaplastic large cell lymphoma Leukemia (IF 12.8) Pub Date : 2024-11-26 Timothy I. Shaw, Stanley Pounds, Xueyuan Cao, Jing Ma, Gustavo Palacios, John Mason, Sherrie Perkins, Gang Wu, Yiping Fan, Jian Wang, Xin Zhou, Alyssa Obermayer, Marsha C. Kinney, Jacqueline Kraveka, Thomas Gross, John Sandlund, Jinghui Zhang, Charles Mullighan, Megan S. Lim, Vasiliki Leventaki
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High CD44 expression and enhanced E-selectin binding identified as biomarkers of chemoresistant leukemic cells in human T-ALL Leukemia (IF 12.8) Pub Date : 2024-11-24 Julien Calvo, Irina Naguibneva, Anthony Kypraios, Florian Gilain, Benjamin Uzan, Baptiste Gaillard, Lea Bellenger, Laurent Renou, Christophe Antoniewski, Helene Lapillonne, Arnaud Petit, Paola Ballerini, Stéphane JC. Mancini, Tony Marchand, Jean-François Peyron, Françoise Pflumio
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Dimethyl fumarate and extracorporeal photopheresis combination-therapy synergize in inducing specific cell death and long-term remission in cutaneous T cell lymphoma Leukemia (IF 12.8) Pub Date : 2024-11-23 Özge Ç. Şener, Susanne Melchers, Luisa Tengler, Paul L. Beltzig, Jana D. Albrecht, Deniz Tümen, Karsten Gülow, Jochen S. Utikal, Sergij Goerdt, Tobias Hein, Jan P. Nicolay
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miR-196b-Oct1/2 axis regulates DNMT3A-mutant AML pathogenesis Leukemia (IF 12.8) Pub Date : 2024-11-23 Michael E. Lawler, Melanie L. Goetz, Jennifer S. Romer-Seibert, Holly A. Gamlen, Edwina McGlinn, Sara E. Meyer
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Dimethyl fumarate ameliorates chronic graft-versus-host disease by inhibiting Tfh differentiation via Nrf2 Leukemia (IF 12.8) Pub Date : 2024-11-23 Fulian Lyu, Huanle Gong, Xiaojin Wu, Xin Liu, Yinghao Lu, Xiya Wei, Chenchen Liu, Yaoyao Shen, Yuhang Wang, Lei Lei, Jia Chen, Shoubao Ma, Hongjian Sun, Di Yu, JingJing Han, Yang Xu, Depei Wu
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A DNA methylation database of human and mouse hematological malignancy cell lines Leukemia (IF 12.8) Pub Date : 2024-11-22 Aleix Noguera-Castells, Carlos A. García-Prieto, Gerardo Ferrer, Veronica Davalos, Fernando Setien, Eulàlia Genescà, Jordi Ribera, Josep M. Ribera, Manel Esteller
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Rheumatoid arthritis and the risk of hematologic malignancies: a nationwide cohort study Leukemia (IF 12.8) Pub Date : 2024-11-22 In Young Cho, Kyungdo Han, Jin Hyung Jung, Mi Hee Cho, Dagyeong Lee, Keun Hye Jeon, Dong Wook Shin
The autoimmune and inflammatory pathogenesis of rheumatoid arthritis (RA), the use of immunomodulating therapy, and shared environmental or genetic risk factors between RA and malignancies have raised attention to cancer risk in patients with RA [1], in particular hematologic malignancies [1, 2]. In RA, the presence of autoantibodies is associated with rapid disease progression; however, it is unclear
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CLL crosstalk with naïve T cells enhances the differentiation of IL-22-producing T cells and CLL -cell survival Leukemia (IF 12.8) Pub Date : 2024-11-22 Gerardo Ferrer, Florencia Palacios, Pui Yan Chiu, Kelly Wong, Alberto Bueno-Costa, Jacqueline C. Barrientos, Jonathan E. Kolitz, Steven L. Allen, Kanti R. Rai, Shih-Shih Chen, Barbara Sherry, Nicholas Chiorazzi
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The co-receptor Neuropilin-1 enhances proliferation in inv(16) acute myeloid leukemia via VEGF signaling Leukemia (IF 12.8) Pub Date : 2024-11-21 Mahesh Hegde, Mohd H. Ahmad, Roger Mulet Lazaro, Mayumi Sugita, Rui Li, Kai Hu, Claudia Gebhard, Monica L. Guzman, John H. Bushweller, Lihua J. Zhu, Michael Brehm, Scot A. Wolfe, Ruud Delwel, Lucio H. Castilla
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Clonal hematopoiesis in large granular lymphocytic leukemia Leukemia (IF 12.8) Pub Date : 2024-11-21 Naomi Kawashima, Carmelo Gurnari, Carlos Bravo-Perez, Yasuo Kubota, Simona Pagliuca, Luca Guarnera, Nakisha D. Williams, Arda Durmaz, Arooj Ahmed, Danai Dima, Fauzia Ullah, Hetty E. Carraway, Abhay Singh, Valeria Visconte, Jaroslaw P. Maciejewski
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Adding eltrombopag to intensive immunosuppressive therapy for severe aplastic anaemia may help adult patients achieve outcomes similar to paediatric patients Leukemia (IF 12.8) Pub Date : 2024-11-21 Bixi Yang, Leyu Wang, Lingling Fu, Miao Chen, Jie Ma, Bing Han
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Global patterns of leukemia by subtype, age, and sex in 185 countries in 2022 Leukemia (IF 12.8) Pub Date : 2024-11-20 Dagrun S. Daltveit, Eileen Morgan, Murielle Colombet, Eva Steliarova-Foucher, Karima Bendahhou, Rafael Marcos-Gragera, Zheng Rongshou, Alexandra Smith, Hui Wei, Isabelle Soerjomataram
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Polycomb group protein Mel18 inhibits hematopoietic stem cell self-renewal through repressing the transcription of self-renewal and proliferation genes Leukemia (IF 12.8) Pub Date : 2024-11-19 Wenjie Cai, Xicheng Liu, Sergio Barajas, Shiyu Xiao, Sasidhar Vemula, Hongxia Chen, Yuxia Yang, Christopher Bochers, Danielle Henley, Sheng Liu, Yuzhi Jia, Michelle Hong, Tiffany M. Mays, Maegan L. Capitano, Huiping Liu, Peng Ji, Zhonghua Gao, Diego Pasini, Jun Wan, Feng Yue, Leonidas C. Platanias, Rongwen Xi, Sisi Chen, Yan Liu
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Graft-versus-host disease after anti-CD19 chimeric antigen receptor T-cell therapy following allogeneic hematopoietic cell transplantation: a transplant complications and paediatric diseases working parties joint EBMT study Leukemia (IF 12.8) Pub Date : 2024-11-19 Guillermo Ortí, Christophe Peczynski, William Boreland, Maeve O’Reilly, Malte von Bonin, Adriana Balduzzi, Caroline Besley, Krzysztof Kalwak, Samppa Ryhänen, Tayfun Güngör, Robert F. Wynn, Peter Bader, Stephan Mielke, Didier Blaise, Persis Amrolia, Ibrahim Yakoub-Agha, Friso Calkoen, Maria-Luisa Schubert, Victoria Potter, Herbert Pichler, Nicolaus Kröger, Mi Kwon, Henrik Sengeloev, Anna Torrent, Yves
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Glucose uptake capacity of leukaemia cells in vitro correlates with response to induction therapy in acute myeloid leukaemia Leukemia (IF 12.8) Pub Date : 2024-11-18 Suqi Deng, Juan Du, Kexiu Huang, Robert Peter Gale, Danqi Pan, Lu Wang, Junjie Wei, Xue Zheng, Ying Xu, Shengqian Xie, Wei Zhou, Weihao Xiao, Bo Liu, Zhiyang Chen, Zhenyu Ju, Hui Zeng
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A phase II trial of ipilimumab, nivolumab, or ipilimumab and nivolumab with or without azacitidine in relapsed or refractory myelodysplastic neoplasms Leukemia (IF 12.8) Pub Date : 2024-11-17 Ian M. Bouligny, Guillermo Montalban-Bravo, Koji Sasaki, Naval Daver, Elias Jabbour, Yesid Alvarado, Courtney D. DiNardo, Farhad Ravandi, Gautam Borthakur, Naveen Pemmaraju, Tapan Kadia, Lucia Masarova, Koichi Takahashi, Michael Andreeff, Alexandre Bazinet, Hui Yang, Rashmi Kanagal, Sherry Pierce, Meghan Meyer, Xuelin Huang, Guillermo Garcia-Manero
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The glycosyltransferase ST3GAL4 drives immune evasion in acute myeloid leukemia by synthesizing ligands for the glyco-immune checkpoint receptor Siglec-9 Leukemia (IF 12.8) Pub Date : 2024-11-17 Vignesh Krishnamoorthy, John Daly, Jimmy Kim, Lidia Piatnitca, Katie A. Yuen, Bhoj Kumar, Mehrnoush Taherzadeh Ghahfarrokhi, Tom Q. T. Bui, Parastoo Azadi, Ly P. Vu, Simon Wisnovsky
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A CADASIL NOTCH3 mutation leads to clonal hematopoiesis and expansion of Dnmt3a-R878H hematopoietic clones Leukemia (IF 12.8) Pub Date : 2024-11-13 Raúl Sánchez-Lanzas, Justin Barclay, Alexandros Hardas, Foteini Kalampalika, Amanda Jiménez-Pompa, Paolo Gallipoli, Miguel Ganuza
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Venetoclax in combination with hypomethylating agents in chronic myelomonocytic leukemia: a propensity score matched multicenter cohort study Leukemia (IF 12.8) Pub Date : 2024-11-12 Douglas Tremblay, Clifford Csizmar, Courtney D. DiNardo, Somedeb Ball, Noa Rippel, Danielle Hammond, Tapan M. Kadia, Farhad Ravandi, Kelly Chien, Grace Van Hyfte, Madhu Mazumdar, Antoine Saliba, Abhishek Mangaonkar, Terra Lasho, Aref Al-Kali, Marina Kremyanskaya, Jonathan Feld, Lewis R. Silverman, Rami Komrokji, John Mascarenhas, Eric Padron, Guillermo Garcia-Manero, David A. Sallman, Mrinal M. Patnaik
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Endothelial heterogeneity in bone marrow: insights across development, adult life and leukemia Leukemia (IF 12.8) Pub Date : 2024-11-11 I. L. Boueya, L. Sandhow, J. R. P. Albuquerque, R. Znaidi, D. Passaro
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Genomic profiling of circulating tumor DNA for childhood cancers Leukemia (IF 12.8) Pub Date : 2024-11-10 Shaohua Lei, Sujuan Jia, Sunitha Takalkar, Ti-Cheng Chang, Xiaotu Ma, Karol Szlachta, Ke Xu, Zhongshan Cheng, Yawei Hui, Selene C. Koo, Paul E. Mead, Qingsong Gao, Priyadarshini Kumar, Colin P. Bailey, Jobin Sunny, Alberto S. Pappo, Sara M. Federico, Giles W. Robinson, Amar Gajjar, Jeffrey E. Rubnitz, Sima Jeha, Ching-Hon Pui, Hiroto Inaba, Gang Wu, Jeffery M. Klco, Ruth G. Tatevossian, Charles G.
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The effect of methylation on the let-7-BCL2L1-BCL2 axis and the potential use of hypomethylating and BH3 mimetic drugs in histiocytic neoplasms Leukemia (IF 12.8) Pub Date : 2024-11-08 Mali Salmon-Divon, Refael Meyuchas, Ofer Shpilberg, Elimelech Okon, Jamal Benhamida, Mariko Yabe, Kseniya Petrova-Drus, Tal Zvida-Bloch, May Basood, Roei Mazor, Benjamin H. Durham, Julien Haroche, Omar Abdel-Wahab, Eli L. Diamond, Oshrat Hershkovitz-Rokah
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Rapid growth of acquired UBA1 mutations predisposes male patients to low-risk MDS Leukemia (IF 12.8) Pub Date : 2024-11-08 Peng Li, F. N. U. Alnoor, Wei Xie, Margaret Williams, Julie Feusier, Yi Ding, Xiangrong Zhao, Gang Zheng, Chen Zhao, Arthur W. Zieske, Youli Zu, Philipp W. Raess, Srinivas Tantravahi, Afaf Osman, Ami B. Patel, Tsewang Tashi, Jay L. Patel, Anna P. Matynia, Madhu P. Menon, Rodney R. Miles, Jeffrey R. Jacobsen, Tracy I. George, Douglas W. Sborov, Philippe Szankasi, Paul Rindler, Devin Close, Robert S
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Genome-first determination of the prevalence and penetrance of eight germline myeloid malignancy predisposition genes: a study of two population-based cohorts Leukemia (IF 12.8) Pub Date : 2024-11-06 Rachel M. Hendricks, Jung Kim, Jeremy S. Haley, Mark Louie Ramos, Uyenlinh L. Mirshahi, David J. Carey, Douglas R. Stewart, Lisa J. McReynolds
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YTHDC1 is a therapeutic target for B-cell acute lymphoblastic leukemia by attenuating DNA damage response through the KMT2C-H3K4me1/me3 epigenetic axis Leukemia (IF 12.8) Pub Date : 2024-11-05 Xinxin Li, Minhua Zheng, Shoubao Ma, Fengze Nie, Zhiqiang Yin, Yanan Liang, Xianchun Yan, Weihong Wen, Jianhua Yu, Yingmin Liang, Siyong Huang, Hua Han
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Pre-emptive therapeutic decisions based on measurable residual disease status in acute myeloid leukemia: ready for prime time? Leukemia (IF 12.8) Pub Date : 2024-11-05 Firas El Chaer, Anthony J. Perissinotti, Sanam Loghavi, Amer M. Zeidan
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Transcriptional regulatory program controlled by MYB in T-cell acute lymphoblastic leukemia Leukemia (IF 12.8) Pub Date : 2024-11-02 Xiaoman Shao, Rui Yokomori, Jolynn Zu Lin Ong, Haoqing Shen, Dennis Kappei, Leilei Chen, Allen Eng Juh Yeoh, Shi Hao Tan, Takaomi Sanda
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Post-transplant cyclophosphamide separates graft-versus host disease and graft versus leukemia effects after HLA-matched stem-cell transplantation for acute myeloid leukemia Leukemia (IF 12.8) Pub Date : 2024-10-31 Avichai Shimoni, Christophe Peczynski, Myriam Labopin, Alexander Kulagin, Ellen Meijer, Jan Cornelissen, Goda Choi, Jaime Sanz, Montserrat Rovira, Gwendolyn Van Gorkom, Nicolaus Kröger, Yener Koc, Jan Vydra, J. L. Diez-Martin, Carlos Solano, Amit Patel, Patrizia Chiusolo, Fabio Ciceri, Arnon Nagler, Mohamad Mohty
The association of graft-versus-host disease (GVHD) and graft-versus-leukemia (GVL) effects after allogeneic stem-cell transplantation (SCT) is well-established but was not confirmed in the modern era and following post-transplant cyclophosphamide (PTCy). We assessed GVHD/ GVL association in AML patients following HLA-matched SCT with standard calcineurin-based (n = 12,653, 57% with additional in-vivo
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The dynamic evolution of lineage switch under CD19 CAR-T treatment in non-KMT2A rearranged B-ALL patients Leukemia (IF 12.8) Pub Date : 2024-10-31 Shaowei Qiu, Yihan Mei, Runxia Gu, Yu Liu, Manling Chen, Haiyan Xing, Kejing Tang, Zheng Tian, Qing Rao, Donglin Yang, Aiming Pang, Shuning Wei, Yujiao Jia, Huijun Wang, Sizhou Feng, Hui Wei, Ping Zhu, Min Wang, Ying Wang, Wenbing Liu, Jianxiang Wang
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Comparative small molecule screening of primary human acute leukemias, engineered human leukemia and leukemia cell lines Leukemia (IF 12.8) Pub Date : 2024-10-29 Safia Safa-Tahar-Henni, Karla Páez Martinez, Verena Gress, Nayeli Esparza, Élodie Roques, Florence Bonnet-Magnaval, Mélanie Bilodeau, Valérie Gagné, Eva Bresson, Sophie Cardin, Nehme El-Hachem, Isabella Iasenza, Gabriel Alzial, Isabel Boivin, Naoto Nakamichi, Anne-Cécile Soufflet, Cristina Mirela Pascariu, Jean Duchaine, Simon Mathien, Éric Bonneil, Kolja Eppert, Anne Marinier, Guy Sauvageau, Geneviève
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Validation and refinement of the 2022 European LeukaemiaNet genetic risk classification of acute myeloid leukaemia patients receiving allogeneic haematopoietic cell transplantation Leukemia (IF 12.8) Pub Date : 2024-10-28 Weihao Chen, Lieguang Chen, Yang Cao, Chuanhe Jiang, Yi Luo, Guifang Ouyang, Jian Yu, Yamin Tan, Xiaoyu Lai, Lizhen Liu, Huarui Fu, Yishan Ye, Luxin Yang, Congxiao Zhang, Jimin Shi, Xiaoxia Hu, He Huang, Yanmin Zhao
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Aberrant BCAT1 expression augments MTOR activity and accelerates disease progression in chronic lymphocytic leukemia Leukemia (IF 12.8) Pub Date : 2024-10-25 Qiangqiang Shao, Jedrzej Wykretowicz, Nan Hu, Karan Bedi, Mohamed Rizk, Isabella A. Malek, Surinder Kumar, David B. Lombard, Kerby Shedden, David Scott, Sami N. Malek
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Antibody blockade of the PSGL-1 immune checkpoint enhances T-cell responses to B-cell lymphoma Leukemia (IF 12.8) Pub Date : 2024-10-25 João L. Pereira, Liliana Arede, Francisca Ferreira, Andreia Matos, Dulcineia Pereira, Rita F. Santos, Alexandre M. Carmo, Maria J. Oliveira, José C. Machado, Delfim Duarte, Nuno R. dos Santos
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Leveraging CRISPR gene editing technology to optimize the efficacy, safety and accessibility of CAR T-cell therapy Leukemia (IF 12.8) Pub Date : 2024-10-25 Tao Lei, Yazhuo Wang, Yuchen Zhang, Yufei Yang, Jiaying Cao, Jiansong Huang, Jiali Chen, Huajing Chen, Jiayi Zhang, Luzheng Wang, Xinjie Xu, Robert Peter Gale, Liang Wang
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Apoliprotein E-mediated ferroptosis controls cellular proliferation in chronic lymphocytic leukemia Leukemia (IF 12.8) Pub Date : 2024-10-23 Federica Nardi, Rosita Del Prete, Roberta Drago, Anthea Di Rita, Francesco Edoardo Vallone, Sara Ciofini, Margherita Malchiodi, Laura Pezzella, Laura Tinti, Vittoria Cicaloni, Laura Salvini, Danilo Licastro, Aidan T. Pezacki, Christopher J. Chang, Giuseppe Marotta, Antonella Naldini, Silvia Deaglio, Tiziana Vaisitti, Alessandro Gozzetti, Monica Bocchia, Anna Kabanova
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NPM1-fusion proteins promote myeloid leukemogenesis through XPO1-dependent HOX activation Leukemia (IF 12.8) Pub Date : 2024-10-23 Yuko Shimosato, Keita Yamamoto, Yuhan Jia, Wenyu Zhang, Norio Shiba, Yasuhide Hayashi, Shuichi Ito, Toshio Kitamura, Susumu Goyama
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MSI2 mediates WNT/β-Catenin pathway function in hematopoietic stem cells Leukemia (IF 12.8) Pub Date : 2024-10-22 Huifang Zhang, Ruixue Guo, Zhenfen Li, Rui Ma, Shina Xu, Le Yin, Hongkai Zhu, Zineng Huang, Cheng Xing, Yunlong Yang, Yulin Pu, Zhao Cheng, Jing Liu, Hongling Peng, Yue Sheng
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The BIM deletion polymorphism potentiates the survival of leukemia stem and progenitor cells and impairs response to targeted therapies Leukemia (IF 12.8) Pub Date : 2024-10-22 Mengge Yu, Giselle Sek Suan Nah, Vaidehi Krishnan, Fatin Nasha Bte Sulaimi, King Pan Ng, Chuqi Wang, Shruti Bhatt, Charles Chuah, David E. Bergstrom, S. Tiong Ong
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Robust anti-myeloma effect of TAS0612, an RSK/AKT/S6K inhibitor, with venetoclax regardless of cytogenetic abnormalities Leukemia (IF 12.8) Pub Date : 2024-10-22 Haruya Okamoto, Shinsuke Mizutani, Taku Tsukamoto, Yoko Katsuragawa-Taminishi, Yuka Kawaji-Kanayama, Kentaro Mizuhara, Ayako Muramatsu, Reiko Isa, Takahiro Fujino, Yuji Shimura, Koji Ichikawa, Junya Kuroda
更新日期：2024-12-16
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