Two studies reveal high transmissibility and lethality of the viral isolate in animal models, and hint at potential drug susceptibility — but further analysis and ongoing surveillance of infections will be critical for public health.

We need to improve carers’ skills in diabetes management and technology, writes Martin Scivier As an older person living with diabetes, I am apprehensive about the current and future care of older people with diabetes in UK nursing and residential care homes. This is an area that has been neglected over the years.1 It worries me that I may have to rely on untrained carers who may not fully understand

Regular attacks on health facilities, workers, and patients in conflicts are a devastating reality Since 2018, the World Health Organization (WHO) has documented over 7400 attacks on healthcare in armed conflict across 21 countries and territories.1 WHO defines an attack on healthcare as any act of verbal, physical violence, obstruction, or threat of violence that interferes with the availability,

“Do you remember that child you saw two days ago?” All doctors dread what might come next: we fear that something bad has happened because we missed a clinical sign or made a poor judgment. This kind of worry keeps us all alert, even at the end of a busy day as the duty doctor. Hospitals have developed scoring systems to help medical and nursing staff gauge how sick a child is, and the Royal College

Action to prevent antimicrobial resistance from escalating requires dedicated funding, accessible diagnostics, and public engagement, writes Ara Darzi Antimicrobial resistance (AMR) is one of the starkest public health challenges of our time. As bacteria evolve and develop resistance to treatment, antibiotics and other drugs become ineffective. This poses a threat that could reverse a century of medical

Disinformation is the new normal with far reaching implications for society, including population health. Martin McKee and colleagues outline the challenges and propose a way forward Donald Trump did not win the 2020 election, but asserting that he did became a prerequisite for Republicans standing for nomination to Congress or the Senate to win their primaries. An entire party became a vehicle for

Julia and Malcolm Donaldsondonaldson20241111.f1 Malcolm Donaldson was a distinguished paediatric endocrinologist with a string of research publications to his name—but he was also happy to play second fiddle (almost literally) to his wife Julia, the celebrated author of much loved children’s books, including The Gruffalo and Room on the Broom. Malcolm, a talented musician and performer, accompanied

I agree with Mahase that many challenges exist in endometriosis diagnosis and management, but there has been some progress in this area.1 As Mahase mentions, Australia launched the National Action Plan for Endometriosis in 2018.2 This pivotal report focused on three main areas: awareness and education; clinical management and care; and research. It was followed by …

Increases will be tempered by low productivity growth The government announced £41bn of tax rises in the October 2024 budget, which, according to the Resolution Foundation think tank, takes tax as a share of national income to a post-war record high.1 Post-pandemic, the UK is moving towards a level of taxation closer to that in other high income countries,2 but it remains to be seen if this can improve

No Abstract

No Abstract

### What you need to know James is a 16 year old boy who lives in a residential (children’s) home. Over the past two months, he has regularly gone missing, returning with new clothes and a new smartphone and laptop. He has been dropped off by different cars late at night. His reluctance to offer explanations for his absences and new possessions raised concerns among care workers. He presents to the

### What you need to know Child abuse and neglect, collectively known as maltreatment, is common, and most healthcare providers who care for children will encounter some form of maltreatment in their practice.1 Common presentations include physical abuse, sexual abuse and commercial sexual exploitation of children, and neglect. In this article, we make recommendations for frontline healthcare providers

Helen Jackson gently asked patients who arrived at the clinic where she practised in Malé, the capital of the Maldives, “Haalu kihineh? Rangalhu tha?”—“How are you? Are you okay?” Primary care is held in low esteem in this South Asian island state, and patients often arrived at the capital’s dedicated pain clinic hoping to be seen by a specialist, rather than by Jackson, a British GP. They also arrived

Donald Trump is the new US president after an ill tempered campaign that saw abortion dominate on the Democratic side but healthcare a minor part of the overall election discourse. Joanne Silberner reports on the medical issues that were debated—and what this may bode for the new president’s agenda The route to the US presidency this election season was a wild ride, marked by a relatively last minute

Standardising practice can improve identification and reduce bias Even for the most experienced healthcare providers, recognising and evaluating suspected child maltreatment or exploitation is challenging. The pressure to make the correct diagnosis is extremely high. Failing to recognise maltreatment can result in the child experiencing severe harm or even death. Conversely, incorrect diagnoses of

Ike Anya talks to Kathy Oxtoby about how he realised his dream of having a published memoir When Ike Anya was working his way through medical training in Nigeria his grandmother reassured him, “Everything worthwhile is achieved small by small.” Some 30 years later, Anya chose that saying as the title of his memoir. “You become a doctor ‘small by small.’ This Nigerian expression is also a lovely way

Tolu Oni and colleagues argue that building healthy low carbon transport infrastructure in Africa’s rapidly growing cities requires addressing historical contexts, confronting power imbalances, and claiming transport as a social good Africa is undergoing rapid urbanisation while facing growing climate vulnerabilities and a rising burden of non-communicable diseases. With global urban growth expected

No Abstract

This Viewpoint discusses enrollment in Medicare Advantage vs traditional Medicare among older adults and common reasons for plan disenrollment, including the lack of in-network physicians and hospitals.

ImportanceCalcific aortic stenosis (AS) restricts the aortic valve opening during systole due to calcification and fibrosis of either a congenital bicuspid or a normal trileaflet aortic valve. In the US, AS affects 1% to 2% of adults older than 65 years and approximately 12% of adults older than 75 years. Worldwide, AS leads to more than 100 000 deaths annually.ObservationsCalcific AS is characterized

A gallery of portraits of prominent alumnae of color at Harvard Medical School provides inspiration for diverse current students and makes past sexist practices visible to all.

In this episode of Sharp Scratch, the panel got together to discuss the many reasons why someone might take time out of medical school. They reflected on how decisions to take time out are often viewed negatively by others, and why taking time out can be beneficial, regardless of the reason behind it. In this episode, the panel, Éabha and Nat, were joined by Kate Owen, who is director of medical studies

Academic norms include: preservation of academic autonomy; integrity in academic practices; a priori formulation of hypotheses and publication of protocols; the use of appropriate methods by which evidence is obtained; the use of appropriate methods for interpreting the accumulated knowledge so obtained; the need to take heed of the possible consequences, both intended and unintended, of research;

BackgroundTransfusion-dependent β-thalassaemia (TDT) is a severe disease, resulting in lifelong blood transfusions, iron overload, and associated complications. Betibeglogene autotemcel (beti-cel) gene therapy uses autologous haematopoietic stem and progenitor cells (HSPCs) transduced with BB305 lentiviral vector to enable transfusion independence. MethodsHGB-212 was a non-randomised, multicentre,

No Abstract

No abstract is available for this article.

A study based in the United Kingdom reports that, in general, most women between the ages of 15 and 39 years who have survived a cancer diagnosis are at low risk for pregnancy complications later in their lives. The study appears in The Lancet Oncology (doi:10.1016/S1470-2045(24)00269-9). According to the study authors, limited data are available on the risks of obstetric complications among survivors

“While it’s been known for some time in the surgical literature that bilateral mastectomy does not impact mortality, this study more clearly confirms that through large sample sizes, length of prospective follow-up, and thoughtful subgroup analysis.” —Monique Gary, DO Although rates of contralateral prophylactic mastectomy and bilateral mastectomy are increasing among women with unilateral sporadic

No Abstract

BackgroundThe Human Development Index (HDI)—a composite metric encompassing a population's life expectancy, education, and income—is used widely for assessing and comparing human development and wellbeing at the country level, but does not account for within-country inequality. In this study of the USA, we aimed to adapt the HDI framework to measure the HDI at an individual level to examine disparities

No Abstract

No Abstract

BackgroundThe loss of corneal epithelial stem cells from the limbus at the edge of the cornea has severe consequences for vision, with the pathological manifestations of a limbal stem-cell deficiency (LSCD) difficult to treat. Here, to the best of our knowledge, we report the world's first use of corneal epithelial cell sheets derived from human induced pluripotent stem cells (iPSCs) to treat LSCD

No Abstract

No Abstract

No Abstract

No Abstract

No Abstract

No Abstract

Experiential evidence must be open to scrutiny and criticism The literature on development of clinical guidelines generally accepts that patients and carers should be involved in the process.123 Patients contribute subjective and practical knowledge of a condition, including what it feels like, what challenges it poses to living a productive and fulfilling life, and how to manage symptoms and flare-ups

No Abstract

No Abstract

No Abstract

No Abstract

No Abstract

No Abstract

No Abstract

No Abstract

No Abstract

No Abstract

No Abstract

No Abstract

No Abstract

Hickey M, Hunter MS, Crandall CJ, et al. Reflections on The Lancet menopause Series. Lancet 2024; 404: 1307–08—In this Correspondence, the order of the author list and Hadine Joffe's name were incorrect. These corrections have been made to the online version as of Nov 7, 2024.

Section snippets ContributorsWe were all involved in the patient's care. KN conceived the paper and drafted the manuscript. All the authors reviewed, edited, and approved the final manuscript. Written consent for publication was obtained from the patient. Declaration of interestsWe declare no competing interests.