-
The oral microbiota and periodontal health in orthodontic patients Periodontol. 2000 (IF 17.5) Pub Date : 2024-07-20 Brandon W. Peterson, Geerten‐Has Tjakkes, Anne‐Marie Renkema, David J. Manton, Yijin Ren
The oral microbiota develops within the first 2 years of childhood and becomes distinct from the parents by 4 years‐of‐age. The oral microbiota plays an important role in the overall health/symbiosis of the individual. Deviations from the state of symbiosis leads to dysbiosis and an increased risk of pathogenicity. Deviations can occur not only from daily life activities but also from orthodontic interventions
-
Comparative osseointegration of hydrophobic tissue‐level tapered implants—A preclinical in vivo study Clin. Oral. Implants Res. (IF 4.8) Pub Date : 2024-07-20 Jean‐Claude Imber, Azita Khandanpour, Andrea Roccuzzo, Delia R. Irani, Dieter D. Bosshardt, Anton Sculean, Benjamin E. Pippenger
PurposeTo histometrically compare the osseointegration and crestal bone healing of a novel tapered, self‐cutting tissue‐level test implant with a standard tissue‐level control implant in a submerged healing regimen.Materials and MethodsIn a mandibular minipig model, implants were inserted and evaluated histometrically after a healing period of 3, 6, and 12 weeks. The primary outcome was the evaluation
-
The efficacy of reconstructive therapy in the surgical management of peri‐implantitis: A 3‐year follow‐up of a randomized clinical trial J. Clin. Periodontol. (IF 5.8) Pub Date : 2024-07-18 Stefan Renvert, Jean‐Louis Giovannoli, Sven Rinke
AimTo assess whether guided bone regeneration (GBR) treatment of peri‐implantitis‐related bony defects could improve healing compared to open flap debridement (OFD) at 36 months.Materials and MethodsIn a multi‐centre, randomized clinical trial, 32 individuals received OFD (control group [CG]) and 34 GBR treatment (test group [TG]). Radiographic defect fill (RDF), probing pocket depth (PPD), bleeding
-
Correction to “Selective BET inhibitor RVX‐208 ameliorates periodontal inflammation and bone loss” J. Clin. Periodontol. (IF 5.8) Pub Date : 2024-07-18
-
Oxidative balance scores in Korean adults are associated with periodontitis J. Periodontol. (IF 4.2) Pub Date : 2024-07-18 Jeong‐Hwa Seon, Na‐Yeong Kim, Ji‐Eun Kim, Choong‐Ho Choi, Ki‐Ho Chung
BackgroundThe Oxidative Balance Score (OBS) is a comprehensive metric that assesses the state of a person's oxidative balance. This study aimed to investigate the relationship between the oxidative balance score and moderate and severe periodontitis in a representative sample of Korean adults.MethodsHealthcare big data from the 7th Korea National Health and Nutrition Examination Survey (2016–2018)
-
Mendelian randomization studies of periodontitis: Understanding benefits and natural limitations in an applied context J. Clin. Periodontol. (IF 5.8) Pub Date : 2024-07-17 Simon Haworth, Nicholas J. Timpson, Kimon Divaris
Mendelian randomization (MR) is a flexible analytical tool that has been widely applied to strengthen causal inference in observational epidemiology and is now gaining attention in many areas including periodontal research. The interpretation of results drawn from MR is based on a series of assumptions, which can be unrealistic or difficult to meet faithfully in some settings. However, we argue that
-
Realizing the clinical utility of saliva for monitoring oral diseases Periodontol. 2000 (IF 17.5) Pub Date : 2024-07-16 Jeffrey L. Ebersole, Hatice Hasturk, Michaell Huber, Robert Gellibolian, Adam Markaryan, Xiaohua D. Zhang, Craig S. Miller
In the era of personalized/precision health care, additional effort is being expended to understand the biology and molecular mechanisms of disease processes. How these mechanisms are affected by individual genetics, environmental exposures, and behavioral choices will encompass an expanding role in the future of optimally preventing and treating diseases. Considering saliva as an important biological
-
Non‐surgical retreatment versus papillary preservation flap surgery for residual pockets: A randomized controlled trial with clinical and patient‐reported outcomes J. Clin. Periodontol. (IF 5.8) Pub Date : 2024-07-16 Luigi Barbato, Desirée Noce, Maria Di Martino, Walter Castelluzzo, Folco Spoleti, Cosimo Rupe, Michele Nieri, Francesco Cairo
AimTo compare the efficacy of non‐surgical re‐instrumentation (NSR) and papillary preservation flap (PPF) surgery at single‐rooted teeth with residual pockets.Materials and MethodsPatients with at least a residual pocket depth (PD ≥ 5 mm) after Steps I and II were enrolled and randomly assigned to receive NSR or PPF surgery. The primary outcome was PD reduction, and secondary outcomes were clinical
-
In vitro comparison of zinc‐based, chlorhexidine, and essential oil mouth rinses J. Periodontol. (IF 4.2) Pub Date : 2024-07-16 Thomas E. Lallier, Brian S. Goldfarb, Pooja Maney
BackgroundChlorhexidine (CHX)‐based mouth rinses are frequently prescribed following periodontal surgeries. A more recently available brand of zinc‐based mouth rinses advertises one of its mouth rinses as a substitute for chlorhexidine. The purpose of this study was to evaluate, in vitro, the effects of this brand of zinc‐based mouth rinses on cell survival, cell motility, and gene expression of human
-
Disparate effects of sclerostin deletion on alveolar bone and cellular cementum in mice J. Periodontol. (IF 4.2) Pub Date : 2024-07-16 Aonjittra Phanrungsuwan, Michael B. Chavez, Leena A. Eltilib, Tamara N. Kolli, Fatma F. Mohamed, Michelle H. Tan, Cristiane R. Salmon, Francisco H. Nociti, Brian L. Foster
BackgroundCellular cementum (CC) includes cementocytes, cells suspected to regulate CC formation or resorption as osteocytes do in bone. Sclerostin (SOST) is a secreted negative regulator of Wnt/β‐catenin signaling expressed by osteocytes and cementocytes. Osteocyte SOST expression reduces bone formation. We investigated the functional importance of SOST in CC compared with alveolar bone (AB) using
-
Utility of gingival crevicular fluid components for periodontal diagnosis Periodontol. 2000 (IF 17.5) Pub Date : 2024-07-15 Nurcan Buduneli, Başak Bıyıkoğlu, Denis F. Kinane
Periodontal diseases are highly prevalent chronic diseases, and severe periodontitis creates functional and esthetic problems and decreases self‐esteem for a large percentage of the older population worldwide. In many cases of periodontitis, there is no distinct tell‐tale pain that motivates a patient to seek treatment, rather the signs become clinically detectable late, and typically when the disease
-
Association between volatile organic compounds exposure and periodontitis: A representative cross‐sectional study J. Clin. Periodontol. (IF 5.8) Pub Date : 2024-07-15 Haitao Dong, Xueting Wang, Ning Xiao, Xin Yang, Xin Zhang, Piye Niu, Tian Chen
AimPeriodontitis is one of the most common oral diseases and a major cause of tooth loss in adults. Environmental pollution is closely associated with the prevalence of periodontitis. However, few studies have focused on the association between volatile organic compounds (VOCs) and periodontitis. This cross‐sectional study aims to examine whether exposure to VOCs is associated with periodontitis, based
-
Factors affecting radiographic marginal bone resorption at dental implants in function for at least 5 years: A multicenter retrospective study Clin. Oral. Implants Res. (IF 4.8) Pub Date : 2024-07-15 Leonardo Trombelli, Roberto Farina, Cristiano Tomasi, Fabio Vignoletti, Guerino Paolantoni, Francesco Giordano, Luca Ortensi, Anna Simonelli
ObjectiveTo evaluate the influence of patient and implant‐related factors on the changes of marginal bone levels (MBL) at implants with a follow‐up ≥5 years.Materials and MethodsAt baseline (within 6 months from prosthetic insertion) and long‐term (≥5 years after implant placement) visits, interproximal (mesial and distal) MBL were radiographically evaluated. To analyze factors predicting MBL change
-
In vivo experimental study comparing alveolar ridge preservation versus guided bone regeneration after unassisted socket healing at intact and damaged sites in narrow alveolar ridges J. Periodontol. (IF 4.2) Pub Date : 2024-07-15 Hae Jee Shin, Jin‐Young Park, Hsu Kuo Tien, Franz‐Josef Strauss, Jae‐Kook Cha, Jung‐Seok Lee
BackgroundTo compare bone regeneration and dimensional alteration of alveolar ridge at intact and damaged extraction sockets after alveolar ridge preservation (ARP) and implant placement versus unassisted socket healing followed by guided bone regeneration (GBR) with simultaneous implant placement.MethodsIn 6 beagle dogs, 3 types of extraction sockets in the mandible were created: (1) intact sockets
-
Efficiency of oral keratinized gingiva detection and measurement based on convolutional neural network J. Periodontol. (IF 4.2) Pub Date : 2024-07-15 Gokce Aykol‐Sahin, Ozgun Yucel, Nihal Eraydin, Gonca Cayir Keles, Umran Unlu, Ulku Baser
BackgroundWith recent advances in artificial intelligence, the use of this technology has begun to facilitate comprehensive tissue evaluation and planning of interventions. This study aimed to assess different convolutional neural networks (CNN) in deep learning algorithms to detect keratinized gingiva based on intraoral photos and evaluate the ability of networks to measure keratinized gingiva width
-
Quantifying periodontitis‐associated oral dysbiosis in tongue and saliva microbiomes—An integrated data analysis J. Periodontol. (IF 4.2) Pub Date : 2024-07-15 Ren Jie Jacob Chew, Kai Soo Tan, Tsute Chen, Nezar Noor Al‐Hebshi, Charlene Enhui Goh
BackgroundPeriodontitis is primarily driven by subgingival biofilm dysbiosis. However, the quantification and impact of this periodontal dysbiosis on other oral microbial niches remain unclear. This study seeks to quantify the dysbiotic changes in tongue and salivary microbiomes resulting from periodontitis by applying a clinically relevant dysbiosis index to an integrated data analysis.MethodsThe
-
Peri‐implantitis induction and resolution around zirconia versus titanium implants J. Periodontol. (IF 4.2) Pub Date : 2024-07-14 Kaleb C. Esplin, Yi‐Wen Tsai, Kathryn Vela, Anibal Diogenes, Lea El Hachem, Archontia Palaiologou, David L. Cochran, Georgios A. Kotsakis
BackgroundThis study compared titanium and zirconia implant ligature‐induced peri‐implant defect progression and response to regenerative surgical intervention.MethodsEight tissue‐level endosseous implants were placed in 6 mixed‐breed foxhounds, with 2 zirconia and 2 titanium alternating in each hemimandible. Cotton ligatures were placed subgingivally for 16 weeks followed by 8 weeks of spontaneous
-
Subgingival microbial profiles in pre‐ and postmenopausal women: Associations with serum estradiol levels J. Periodontol. (IF 4.2) Pub Date : 2024-07-14 Nil Yakar, Busra Yilmaz, Gulnur Emingil, Tsute Chen, Guven Ozdemir, Alpdogan Kantarci
BackgroundSubgingival dental plaque is an ecosystem playing a key role in supporting both oral health and systemic health. Menopause‐related changes have the potential to disrupt its balance, which is crucial to postmenopausal well‐being. Our study explored how circulating estradiol levels correlate with subgingival microbial composition using checkerboard DNA‐DNA hybridization in premenopausal and
-
Association between masticatory function and depression in older adults: Results from NHANES 2009 to 2018 J. Clin. Periodontol. (IF 5.8) Pub Date : 2024-07-11 Xindi Wei, Xiaomeng Zhang, Xiao Zhang, Ruiying Chen, Maurizio S. Tonetti, Junyu Shi, Hongchang Lai
AimDepression is prevalent among older adults. Although the number of missing teeth is considered to be associated with depression, the relationship between masticatory function, which is usually indicated by functional tooth units (FTUs), and depression in older adults remains unclear.Materials and MethodsThis study used data from the National Health and Nutrition Examination Survey (NHANES) 2009–2018
-
A nomogram‐based predictive model for tooth survival in Chinese patients with periodontitis: An 11‐year retrospective cohort study J. Clin. Periodontol. (IF 5.8) Pub Date : 2024-07-11 Shuwen Shi, Yang Meng, Jian Jiao, Dong Shi, Xianghui Feng, Huanxin Meng
AimTo develop a nomogram‐based predictive model of tooth survival by comprehensively analysing clinical and radiographic risk factors of tooth loss (TL).Materials and MethodsIn this study, 3447 teeth of 131 subjects who underwent non‐surgical periodontal treatment were examined retrospectively within a mean follow‐up period of 11.6 years. The association of risk factors including clinical and radiographic
-
Using SWATH‐MS to identify new molecular biomarkers in gingival crevicular fluid for detecting periodontitis and its response to treatment J. Clin. Periodontol. (IF 5.8) Pub Date : 2024-07-11 T. Blanco‐Pintos, A. Regueira‐Iglesias, M. Relvas, M. Alonso‐Sampedro, M. P. Chantada‐Vázquez, C. Balsa‐Castro, I. Tomás
AimTo identify new biomarkers to detect untreated and treated periodontitis in gingival crevicular fluid (GCF) using sequential window acquisition of all theoretical mass spectra (SWATH‐MS).Materials and MethodsGCF samples were collected from 44 periodontally healthy subjects and 40 with periodontitis (Stages III–IV). In the latter, 25 improved clinically 2 months after treatment. Samples were analysed
-
Evaluation of a newly developed oral and maxillofacial surgical robotic platform (KD-SR-01) in head and neck surgery: a preclinical trial in porcine models Int. J. Oral Sci. (IF 10.8) Pub Date : 2024-07-10 Zhongkai Ma, Zhiyong Guo, Zhangfan Ding, Chang Cao, Jialu He, Heyi Tang, Yufei Hua, Jiawei Hong, Qiang Shen, Grace Paka Lubamba, Xiaoyi Wang, Zheng Yang, Guiquan Zhu, Chunjie Li
-
-
Excessive weight in pregnant women increases the chance of diagnosing periodontitis combined with tooth loss J. Periodontol. (IF 4.2) Pub Date : 2024-07-10 Josicélia Estrela Tuy Batista, Ana Claudia Morais Godoy Figueiredo, Elivan Silva Souza, Amanda Oliveira Lyrio, Johelle Santana Passos‐Soares, Soraya Castro Trindade, Claudia Maria Coêlho Alves, Maria Isabel Pereira Vianna, Julita Maria Freitas Coelho, Sarah dos Santos Conceição, Eneida de Moraes Marcílio Cerqueira, Alexandre Marcelo Hintz, Gregory John Seymour, Frank Andrew Scannapieco, Peter Michael
BackgroundExcess weight (EW), especially in women of childbearing age, those who are pregnant, as well as postpartum, is a problem worldwide. Fat accumulation deregulates the inflammatory response, contributing to the development of health problems, such as periodontitis. This study investigated the association between EW and periodontitis during pregnancy.MethodsA cross‐sectional, multicenter study
-
Root surface biomodification in periodontal therapy: Biological rationale and clinical applications Periodontol. 2000 (IF 17.5) Pub Date : 2024-07-09 Muhammad H. A. Saleh, Debora R. Dias, Andrea Ravida, Hom‐Lay Wang
Regenerative periodontal therapy aims to form new cementum, periodontal ligament, and alveolar bone, all sealed by gingival tissue. The root surface acts as the wound margin during this regeneration process. Root surface biomodification (root conditioning/root decontamination), therefore, seems instrumental in promoting surface decontamination and enhancing tissue attachment by removing the smear layer
-
Association between nonalcoholic fatty liver disease scores and chronic periodontitis: A retrospective cohort study J. Periodontol. (IF 4.2) Pub Date : 2024-07-07 Kwangmin Joo, Yeo Wool Kang, Sang Yi Moon, Yang Hyun Baek, Minkook Son
BackgroundAlthough several studies have demonstrated a bidirectional relationship between nonalcoholic fatty liver disease (NAFLD) and chronic periodontitis, few studies have reported that NAFLD causes chronic periodontitis, especially in the Asian population.MethodsThis study was conducted on 129,087 individuals, and the NAFLD score was assessed using the Fatty Liver Index (FLI), Hepatic Steatosis
-
Low‐dose, standard, and high‐resolution cone beam computed tomography for alveolar bone measurements related to implant planning: An ex vivo study in human specimens Clin. Oral. Implants Res. (IF 4.8) Pub Date : 2024-07-06 Laurits Kaaber, Louise Hauge Matzen, Rubens Spin‐Neto, Lars Schropp
AimTo evaluate the performance of low‐dose cone beam computed tomography (CBCT) protocols with regard to linear bone measurements in the posterior mandible for implant planning compared with higher dose protocols.Materials and MethodsForty‐two edentulous posterior sites in human cadaveric mandibles were imaged in three CBCT scanners using three or four protocols with varying exposure parameters to
-
Periodontal pathogens and cancer development Periodontol. 2000 (IF 17.5) Pub Date : 2024-07-05 Yuxi Zhou, Joerg Meyle, Sabine Groeger
Increasing evidence suggests a significant association between periodontal disease and the occurrence of various cancers. The carcinogenic potential of several periodontal pathogens has been substantiated in vitro and in vivo. This review provides a comprehensive overview of the diverse mechanisms employed by different periodontal pathogens in the development of cancer. These mechanisms induce chronic
-
Association of the Life's Essential 8 cardiovascular health score with periodontitis among US adults J. Clin. Periodontol. (IF 5.8) Pub Date : 2024-07-05 Lang Liang, Chia‐Yu Chen, Izzuddin M. Aris
AimTo investigate whether cardiovascular health (CVH) is associated with periodontitis.Materials and MethodsWe used data from the 2009 to 2014 National Health and Nutrition Examination Survey. We quantified CVH using Life's Essential 8, which includes four health behaviours (diet, smoking, physical activity and sleep) and four health factors (body mass index, blood cholesterol, glucose and pressure)
-
Beyond transcription, aryl hydrocarbon receptor plays a protective role in periodontitis by interacting with CaMKII J. Periodontol. (IF 4.2) Pub Date : 2024-07-05 Xuwen Zeng, Meiting Feng, Jiawei Lu, Ruiling Wang, Li Deng, Yanan Yang, Lijun Luo
BackgroundThe aryl hydrocarbon receptor (AhR) has been studied as an intracellular pattern recognition receptor that can identify bacterial pigments. To identify a potential therapeutic target for periodontitis, we investigated the expression of AhR in periodontitis and its role in the pathogenesis of periodontitis.MethodsFirst, we analyzed AhR expression in a single‐cell dataset from human periodontal
-
Effect of depression and the antidepressant fluoxetine on osseointegration—A pre‐clinical in vivo experimental study Clin. Oral. Implants Res. (IF 4.8) Pub Date : 2024-07-04 Yundeng Xiaowen, Jingxuan Zhu, Mingming Gong, Ge Meng, Renran Tan, Yanbing Zhang, Zhiyu Chen
ObjectiveThe aim of this study was to explore the effect of depression and selective serotonin reuptake inhibitors on implant osseointegration and bone healing.MethodsForty‐eight 6‐ to 8‐week‐old SPF Sprague–Dawley male rats were randomly divided into four groups: the Control group, the Fluoxetine group, the Depression group and the De&Flu group. The rats in the Depression group and the De&Flu group
-
Early implant placement versus ridge preservation and delayed implant placement: Analysis of profilometric, clinician‐ and patient‐reported outcomes from a two‐centre RCT Clin. Oral. Implants Res. (IF 4.8) Pub Date : 2024-07-04 Daniel Thoma, Alfonso Gil, Thomas de Bruyckere, Ronald E. Jung, Shunsuke Fukuba, Axelle Ickroth, Franz J. Strauss, Jan Cosyn
ObjectivesTo compare early implant placement (EP) to alveolar ridge preservation and delayed implant placement (ARP/DP) in terms of contour changes, along with clinician‐ and patient‐reported outcome measures (PROMs) until the delivery of the implant‐supported restoration.Materials and MethodsPatients with a failing single tooth in the maxilla or mandible were recruited in two centres. After tooth
-
Gingipain and oncostatin M synergistically disrupt kidney tight junctions in periodontitis‐associated acute kidney injury J. Periodontol. (IF 4.2) Pub Date : 2024-07-04 Wei Wei, Jing Sun, Zhaoxin Ji, Jiangqi Hu, Qingsong Jiang
BackgroundAcute kidney injury (AKI) is characterized by rapid renal decline. Periodontitis, a chronic oral inflammatory disease, is increasingly associated with renal dysfunction. Although periodontitis is recognized as a contributor to kidney damage, the mechanisms linking it to AKI remain unclear.MethodsThis study explored the effects of Porphyromonas gingivalis (P. gingivalis) W83‐infected periodontitis
-
Supportive periodontal care with or without subgingival instrumentation: Microbiological results of a 2‐year randomized clinical trial J. Clin. Periodontol. (IF 5.8) Pub Date : 2024-07-03 P. D. M. Angst, U. Van der Velden, C. Susin, S. C. Gomes
AimTo compare the subgingival microbiota of patients receiving supportive periodontal care (SPC) with and without subgingival instrumentation, over 2 years.Materials and MethodsThis study was a randomized clinical trial that included 62 participants (50.97 ± 9.26 years old; 40 females) who completed non‐surgical periodontal therapy. Participants were randomly assigned to receive oral prophylaxis with
-
Efficacy of communicating periodontal risk on psychological outcomes and supragingival plaque control in patients undergoing first periodontal consultation: A parallel‐arm, randomized trial J. Clin. Periodontol. (IF 5.8) Pub Date : 2024-07-03 Roberto Farina, Anna Simonelli, Maria Elena Guarnelli, Giacomo Secchiati, Giulia Montemezzo, Chiara Scapoli, Leonardo Trombelli
AimTo evaluate the efficacy of the PerioRisk prognostic tool in implementing the effect of motivational interviewing (MI) on psychological outcomes and supragingival plaque control.Materials and MethodsParticipants underwent MI immediately after their first periodontal visit. According to a parallel‐arm, randomized study design, MI was performed with (RISK group) or without (CTR group) information
-
Association between biological ageing and periodontitis: Evidence from a cross‐sectional survey and multi‐omics Mendelian randomization analysis J. Clin. Periodontol. (IF 5.8) Pub Date : 2024-07-03 Zhendong Huang, Simin Peng, Ting Cen, Xiaoxuan Wang, Li Ma, Zhengguo Cao
AimTo investigate the relationship and potential causality between biological ageing and periodontitis.Materials and MethodsWe obtained the National Health and Nutrition Examination Survey (NHANES) and genome‐wide association study (GWAS) summary statistics as well as single‐cell sequencing data. Multivariate regression analysis based on cross‐sectional data, Mendelian randomization (MR) and multi‐omics
-
Synthetic high-density lipoprotein (sHDL): a bioinspired nanotherapeutics for managing periapical bone inflammation Int. J. Oral Sci. (IF 10.8) Pub Date : 2024-07-02 Renan Dal-Fabbro, Minzhi Yu, Ling Mei, Hajime Sasaki, Anna Schwendeman, Marco C. Bottino
-
Diagnostic measures for monitoring and follow‐up in periodontology and implant dentistry Periodontol. 2000 (IF 17.5) Pub Date : 2024-07-02 Christoph A. Ramseier
This review discusses the role of diagnostic measures in the lifelong management of periodontal disease and peri‐implant complications. After active treatment, these conditions require regular monitoring of the supporting structures of teeth and dental implants to assess bone and soft tissue health over time. Several clinical measures have been developed for the routine assessment of periodontal and
-
Nonionizing diagnostic imaging modalities for visualizing health and pathology of periodontal and peri‐implant tissues Periodontol. 2000 (IF 17.5) Pub Date : 2024-07-02 Andy Wai Kan Yeung, Abeer AlHadidi, Rutvi Vyas, Michael M. Bornstein, Hiroshi Watanabe, Ray Tanaka
Radiographic examination has been an essential part of the diagnostic workflow in periodontology and implant dentistry. However, radiographic examination unavoidably involves ionizing radiation and its associated risks. Clinicians and researchers have invested considerable efforts in assessing the feasibility and capability of utilizing nonionizing imaging modalities to replace traditional radiographic
-
Radiographic assessment of the peri‐implant site Periodontol. 2000 (IF 17.5) Pub Date : 2024-07-02 Philipp Sahrmann, Sebastian Kühl, Dorothea Dagassan‐Berndt, Michael M. Bornstein, Nicola U. Zitzmann
While peri‐implant mucositis relies solely on clinical parameters, radiological assessment becomes indispensable for diagnosing peri‐implantitis. Intraoral radiography, with its simplicity of application, low radiation exposure, and adequate representation of peri‐implant structures, stands out as the standard of care for both immediate and follow‐up assessments. Standardization by custom‐made radiologic
-
Associations between oral health and depression and anxiety: A cross‐sectional and prospective cohort study from the UK Biobank J. Clin. Periodontol. (IF 5.8) Pub Date : 2024-07-02 Jingjing Wang, Yani Wang, Huihui Li, Weijing Wang, Dongfeng Zhang
AimTo investigate the associations between oral health and depression, anxiety and their comorbidity in the UK Biobank cohort.Materials and MethodsOral health problems were self‐reported at baseline. Symptoms of depression and anxiety were assessed using the Mental Health Questionnaire (PHQ‐4) in a cross‐sectional study. In the cohort study, diagnoses of depression and anxiety disorders were based
-
High‐yield nanovesicles extruded from dental follicle stem cells promote the regeneration of periodontal tissues as an alternative of exosomes J. Clin. Periodontol. (IF 5.8) Pub Date : 2024-07-02 Lu Liang, Limeiting Wang, Zhenhui Liao, Liya Ma, Pinwen Wang, Junjie Zhao, Jinyan Wu, Hefeng Yang
AimTo identify an optimized strategy for the large‐scale production of nanovesicles (NVs) that preserve the biological properties of exosomes (EXOs) for use in periodontal regeneration.Materials and MethodsNVs from dental follicle stem cells (DFSCs) were prepared through extrusion, and EXOs from DFSCs were isolated. The yield of both extruded NVs (eNVs) and EXOs were quantified through protein concentration
-
One‐stage prosthodontically driven jaw reconstruction in patients with benign and malignant pathologies: A 7‐ to 11‐year cohort study Clin. Oral. Implants Res. (IF 4.8) Pub Date : 2024-07-02 Vinay V. Kumar, Supriya Ebenezer, Sreelakshmi Viswanath, Andreas Thor
ObjectivesOne stage functional jaw reconstruction is defined as the resection and reconstruction of segmental defects in conjunction with the placement of dental implants in an ideal prosthetic position and loaded with a provisional restoration, during one surgical procedure. The aim of the study is to describe clinical outcomes of patients who underwent one stage functional jaw reconstruction.MethodsPatients
-
RETRACTION: Ultrastructural study by backscattered electron imaging and elemental microanalysis of bone‐to‐biomaterial interface and mineral degradation of porcine xenografts used in maxillary sinus floor elevation Clin. Oral. Implants Res. (IF 4.8) Pub Date : 2024-07-02
M. P. Ramírez‐Fernández, J. L. Calvo‐Guirado, J. E. Maté‐Sánchez del Val, R. A. Delgado‐Ruiz, B. Negri, C. Barona‐Dorado, “Ultrastructural study by backscattered electron imaging and elemental microanalysis of bone‐to‐biomaterial interface and mineral degradation of porcine xenografts used in maxillary sinus floor elevation,” Clinical Oral Implants Research 24, no. 5 (2013): 523–530, https://doi.org/10
-
RETRACTION: Ultrastructural study by backscattered electron imaging and elemental microanalysis of biomaterial‐to‐bone interface and mineral degradation of bovine xenografts in maxillary sinus floor elevation Clin. Oral. Implants Res. (IF 4.8) Pub Date : 2024-07-02
M. P. Ramírez‐Fernández, J. L. Calvo‐Guirado, R. A. Delgado‐Ruiz, J. E. Maté‐Sánchez del Val, B. Negri, M. Peñarrocha Diago, “Ultrastructural study by backscattered electron imaging and elemental microanalysis of biomaterial‐to‐bone interface and mineral degradation of bovine xenografts in maxillary sinus floor elevation,” Clinical Oral Implants Research 24, no. 6 (2013): 645–651, https://doi.org/10
-
Long‐term retention and survival of cemented implant‐supported zirconia and metal‐ceramic single crowns: A retrospective study Clin. Oral. Implants Res. (IF 4.8) Pub Date : 2024-07-02 P. Rammelsberg, A. L. Klotz
ObjectivesTo evaluate the effect of different cement types on the incidence of failure and loss of retention of zirconia and metal‐ceramic single crowns (SCs) cemented on implant abutments.MethodsWe placed 567 implant‐supported SCs in 358 patients and retrospectively evaluated long‐term retention for up to 12.8 years. The frameworks were made from metal alloy (n = 307) or zirconia (n = 260). SCs were
-
Stabilization of EREG via STT3B-mediated N-glycosylation is critical for PDL1 upregulation and immune evasion in head and neck squamous cell carcinoma Int. J. Oral Sci. (IF 10.8) Pub Date : 2024-07-01 Shengming Xu, Haifeng Wang, Yu Zhu, Yong Han, Liu Liu, Xiangkai Zhang, Jingzhou Hu, Wuchang Zhang, Shengzhong Duan, Jiong Deng, Zhiyuan Zhang, Shuli Liu
-
Does an untreated peri‐implant dehiscence defect affect the progression of peri‐implantitis?: A preclinical in vivo experimental study Clin. Oral. Implants Res. (IF 4.8) Pub Date : 2024-07-01 Young Woo Song, Jin‐Young Park, Ji‐Yeong Na, Yoon‐Hee Kwon, Jae‐Kook Cha, Ui‐Won Jung, Daniel S. Thoma, Ronald E. Jung
ObjectiveTo investigate the early impact of plaque accumulation in a buccal dehiscence defect on peri‐implant marginal bone resorption.Materials and MethodsIn six male Mongrel dogs, four dental implants were placed in the posterior maxilla on both sides (two implants per side). Based on the group allocation, each implant was randomly assigned to one of the following four groups to decide whether buccal
-
How well do antimicrobial mouth rinses prevent dysbiosis in an in vitro periodontitis biofilm model? J. Periodontol. (IF 4.2) Pub Date : 2024-07-01 Naiera Zayed, Rik Vertommen, Kenneth Simoens, Kristel Bernaerts, Nico Boon, Mrinal Gaurav Srivastava, Annabel Braem, Wannes Van Holm, Ana B. Castro, Wim Teughels
BackgroundPeriodontal diseases are associated with dysbiosis in the oral microbial communities. Managing oral biofilms is therefore key for preventing these diseases. Management protocols often include over‐the‐counter antimicrobial mouth rinses, which lack data on their effects on the oral microbiome's ecology, bacterial composition, metabolic activity, and dysbiosis resilience. This study examined
-
Single‐piece zirconia versus single‐piece titanium, narrow‐diameter dental implants in the anterior maxilla: 5‐year post‐loading results of a randomized clinical trial Clin. Oral. Implants Res. (IF 4.8) Pub Date : 2024-06-28 Paula Andrea Ruiz Henao, Gabriel Leonardo Magrin, Leticia Caneiro‐Queija, Cesar Augusto Magalhães Benfatti, Yago Leira, Antonio Liñares‐González, Juan Blanco‐Carrión
ObjectivesThe aim of this study was to evaluate esthetic parameters in the anterior maxillary region by comparing single‐piece zirconia versus titanium narrow‐diameter implants. Additionally, clinical, radiological and patient‐reported outcome measures (PROMs) were analyzed.Materials and MethodsThirty implants (tissue level implant) were placed in 30 patients in the maxillary esthetic sector. Depending
-
Harvest of epithelialized gingival grafts without application of hemostatic sutures: A randomized clinical trial using laser speckle contrast imaging J. Periodontol. (IF 4.2) Pub Date : 2024-06-28 David Palombo, Andrea Dobos, Mercedes Lopez Duran, Javier Sanz Esporrin, Mariano Sanz
BackgroundThis randomized controlled trial with two parallel arms and a 1:1 allocation ratio aimed to compare early microvascular healing (primary outcome), surgical times, and patient‐reported outcomes (PROM) after harvesting palatal epithelialized gingival grafts (EGG), where hemostasis was achieved with sutures and hemostatic sponges (control) or with a sutureless approach (test).MethodsFrom a total
-
Cystathionine γ‐lyase contributes to exacerbation of periodontal destruction in experimental periodontitis under hyperglycemia J. Periodontol. (IF 4.2) Pub Date : 2024-06-28 Danni Song, Jiangfeng He, Tianfan Cheng, Lijian Jin, Sijin Li, Beibei Chen, Yongming Li, Chongshan Liao
BackgroundDiabetes is one of the major inflammatory comorbidities of periodontitis via 2‐way interactions. Cystathionine γ‐lyase (CTH) is a pivotal endogenous enzyme synthesizing hydrogen sulfide (H2S), and CTH/H2S is crucially implicated in modulating inflammation in various diseases. This study aimed to explore the potential role of CTH in experimental periodontitis under a hyperglycemic condition
-
Long‐term success and influencing factors of regenerative surgery for intra‐bony defects: A retrospective cohort study J. Periodontol. (IF 4.2) Pub Date : 2024-06-28 Yan Huang, Xiangying Ouyang, Bei Liu, Jianru Liu, Wenyi Liu, Ying Xie
BackgroundThe composite outcome measure (COM) more comprehensively assesses the clinical efficacy of regenerative surgery than a single probing measurement. We aimed to assess long‐term success defined by the COM (clinical attachment level [CAL] gain of ≥3 mm and postsurgery probing pocket depth [PPD] ≤ 4 mm) and influencing factors of regenerative surgery using bone substitutes and resorbable collagen
-
Laser and scanning electron microscopy evaluation of residual microislands of calculus J. Periodontol. (IF 4.2) Pub Date : 2024-06-28 Stephen K. Harrel, Charles M. Cobb, Martha E. Nunn, Donggao Zhao
BackgroundRecent studies suggest a role for microscopic crystalline particles of residual dental calculus in the pathogenesis of periodontitis. The purpose of this ex vivo study was to compare the effectiveness of scaling and root planing (SRP) alone versus SRP combined with 24% ethylenediamine‐tetra acetic acid (EDTA) gel in removing calculus from extracted teeth and to determine the optimal length
-
The use of patient‐related outcomes (PRO) and experience (PRE) in assessing the periodontal and implant patient Periodontol. 2000 (IF 17.5) Pub Date : 2024-06-27 Sirikarn P. Arunyanak, Kajorn Kungsadalpipob, Kyle E. Wright, Keskanya Subbalekha, Irina Dragan, Nikos Mattheos
The purpose of this review was to summarize the evidence with regard to behavioral and psychosocial assessment of the periodontitis patient, the candidate for implant therapy, and the peri‐implantitis patient. Periodontitis has an adverse effect on quality of life and its treatment can lead to significant improvements experienced by the patient. The latter is true for rehabilitation with dental implants
-
Artificial intelligence and personalized diagnostics in periodontology: A narrative review Periodontol. 2000 (IF 17.5) Pub Date : 2024-06-27 Vinay Pitchika, Martha Büttner, Falk Schwendicke
Periodontal diseases pose a significant global health burden, requiring early detection and personalized treatment approaches. Traditional diagnostic approaches in periodontology often rely on a “one size fits all” approach, which may overlook the unique variations in disease progression and response to treatment among individuals. This narrative review explores the role of artificial intelligence
-
Preloading peri‐implant crestal bone loss: A retrospective study of incidence and related factors J. Periodontol. (IF 4.2) Pub Date : 2024-06-26 Nathalia Vilela, Bruno C. V. Gurgel, Carlos De Bruzos, Wagner R. Duarte, Hélio D. P. da Silva, Claudio M. Pannuti, Poliana Mendes Duarte
BackgroundThe aim of this study was to evaluate the incidence of preloading crestal bone loss (PLCBL) and to identify the patient‐related and implant‐related factors associated with PLCBL.MethodsThis retrospective cohort examined the dental records of patients who received at least one dental implant. PLCBL was defined as a reduction ⩾0.5 mm and severe PLCBL (primary variable) as a reduction ⩾1.5 mm
-
-
How to explain the beneficial effects of leukocyte‐ and platelet‐rich fibrin Periodontol. 2000 (IF 17.5) Pub Date : 2024-06-25 Juan Blanco, Angel García Alonso, Lidia Hermida‐Nogueira, Ana B. Castro
The survival of an organism relies on its ability to repair the damage caused by trauma, toxic agents, and inflammation. This process involving cell proliferation and differentiation is driven by several growth factors and is critically dependent on the organization of the extracellular matrix. Since autologous platelet concentrates (APCs) are fibrin matrices in which cells, growth factors, and cytokines
-
Diagnostic methods/parameters to monitor peri‐implant conditions Periodontol. 2000 (IF 17.5) Pub Date : 2024-06-25 Alberto Monje, Giovanni E. Salvi
The diagnostic accuracy of clinical parameters, including visual inspection and probing to monitor peri‐implant conditions, has been regarded with skepticism. Scientific evidence pointed out that primary diagnostic tools (chairside) seem to be highly specific, while their sensitivity is lower compared with their use in monitoring periodontal stability. Nonetheless, given the association between pocket