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Prospective study of urinary incontinence recovery following endoscopic enucleation of the prostate BJU Int. (IF 3.7) Pub Date : 2024-07-19 Shao‐Wei Wu, Chi‐Shin Tseng, Lun‐Hsiang Yuan, Yu‐Wen Huang, Yi‐Jhou Chen, Ming‐Chieh Kuo, Jeff Shih‐Chieh Chueh, Shi‐Wei Huang
ObjectiveTo investigate the clinical trajectories and identify risk factors linked to post‐enucleation urinary incontinence (UI).Patients and MethodsIn this prospective study (April 2020 to March 2022) at a single institution, 316 consecutive patients receiving endoscopic enucleation due to benign prostatic enlargement were included. Patient information and perioperative details were collected. Follow‐ups
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Penile intraepithelial neoplasia incidence, clinical classification, microenvironment and implications for imiquimod treatment BJU Int. (IF 3.7) Pub Date : 2024-07-19 Ofir Avitan, Tynisha Rafael, Manon Vreeburg, Laura Elst, Elise M. Bekers, Maarten Albersen, Ekaterina S. Jordanova, Oscar Brouwer
ObjectivesTo provide an outline of the existing data on penile intraepithelial neoplasia (PeIN), as well as a narrative review on imiquimod (IQ; a toll‐like receptor 7 agonist) treatment and immune microenvironment markers that may predict response to treatment.MethodsA narrative review of the literature from 2000 to the present was conducted on PubMed, and we describe the most relevant data and cross
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Acupuncture: a promising adjuvant strategy for pain management among the patients with prostate cancer BJU Int. (IF 3.7) Pub Date : 2024-07-18 Jie Yang, Xingyu Xiong, Qiang Wei, Lu Yang
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Advanced optical imaging techniques for bladder cancer detection and diagnosis: a systematic review BJU Int. (IF 3.7) Pub Date : 2024-07-17 Marinka J. Remmelink, Yael Rip, Jakko A. Nieuwenhuijzen, Johannes C.F. Ket, Jorg R. Oddens, Theo M. de Reijke, Daniel M. de Bruin
ObjectivesTo systematically assess the current available literature concerning advanced optical imaging methods for the detection and diagnosis of bladder cancer (BCa), focusing particularly on the sensitivity and specificity of these techniques.MethodsFirst a scoping search was performed to identify all available optical techniques for BCa detection and diagnosis. The optical imaging techniques used
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Acupuncture: a strategy for pain management among patients with prostate cancer – authors’ reply BJU Int. (IF 3.7) Pub Date : 2024-07-17 Jean Maurer, Francesca Ambrosini, Yuelai Chen, Sven Schroeder
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Pathological concordance rate and outcomes by subtype in advanced papillary renal cell carcinoma BJU Int. (IF 3.7) Pub Date : 2024-07-17 Abhishek Tripathi, Catherine M. Tangen, Melissa Plets, Xiaochen Li, Maria Tretiakova, Peter A. Humphrey, Adebowale Adeniran, Pedro C. Barata, Shuchi Gulati, Cristiane D. Bergerot, Deepak K. Pruthi, Ian M. Thompson, Primo N. Lara, Seth P. Lerner, Sumanta K. Pal, Brian M. Shuch
ObjectiveTo evaluate the clinical significance of subtyping (type 1 vs 2) of papillary renal cell carcinoma (PRCC) in patients treated with targeted therapy, as well as the concordance, sensitivity and positive predictive value (PPV) of local review pathology review.MethodsPatients with advanced refractory PRCC were randomised to receive sunitinib or cabozantinib, crizotinib or savolitinib, stratified
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‘Case of the Month’ from Addenbrooke's Hospital, Cambridge, UK: surgery after near complete response to combined immunotherapy and tyrosine kinase inhibitor therapy for metastatic renal cell carcinoma with inferior vena cava tumour thrombus BJU Int. (IF 3.7) Pub Date : 2024-07-17 James P. Blackmur, James N. Armitage, James O. Jones, Antony C.P. Riddick, Thomas J. Mitchell, William H.J. Ince, Sona Appukutty, Anne Y. Warren, Kate Fife, Brent O'Carrigan, Grant D. Stewart
Introduction While systemic anti-cancer therapy (SACT) has become the principal management option for many patients with metastatic RCC, there remains debate on the benefits of delayed cytoreductive nephrectomy (CN), and on whether immediate CN and tumour thrombectomy is the correct strategy when there is venous tumour thrombus (VTT) extending into the inferior vena cava (IVC). Given the poor prognosis
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‘Case of the Month’ from Herlev and Gentofte Hospital, Denmark: candidaemia and fungus ball in a patient with diabetes on sodium‐glucose co‐transporter 2 inhibitor BJU Int. (IF 3.7) Pub Date : 2024-07-14 Anne Sofie Frøkiær Mathiasen, Maria Feldborg Bruun Andersen, Valeria Antsupova, Mikkel Fode
Introduction Candida species rarely cause UTIs in healthy individuals. However, glucosuria due to poorly controlled diabetes mellitus (DM) has long been assumed as a risk factor for acquiring UTIs and genital yeast infections [1]. Sodium-glucose co-transporter 2 (SGLT-2) inhibitors are antidiabetic drugs that were introduced to the European market in 2012. These drugs lower blood glucose levels by
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A systematic review on artificial intelligence evaluating PSMA PET scan for intraprostatic cancer BJU Int. (IF 3.7) Pub Date : 2024-07-14 Jianliang Liu, Thomas P. Cundy, Dixon T. S. Woon, Nanadakishor Desai, Marimuthu Palaniswami, Nathan Lawrentschuk
ObjectivesTo assess artificial intelligence (AI) ability to evaluate intraprostatic prostate cancer (PCa) on prostate‐specific membrane antigen positron emission tomography (PSMA PET) scans prior to active treatment (radiotherapy or prostatectomy).Materials and MethodsThis systematic review was registered on the International Prospective Register of Systematic Reviews (PROSPERO identifier: CRD42023438706)
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Comparison of holmium:yttrium‐aluminium‐garnet (YAG), thulium fiber laser, and pulsed thulium:YAG lasers on soft tissue: an ex vivo study BJU Int. (IF 3.7) Pub Date : 2024-07-12 Stessy Kutchukian, Marie Chicaud, Laurent Berthe, Frédéric Coste, Pierre Lapouge, Hussa Alshehhi, David Buob, Olivier Traxer, Frédéric Panthier, Steeve Doizi
ObjectivesTo assess laser–tissue interactions through ablation, coagulation, and carbonisation characteristics in a non‐perfused porcine kidney model between three pulsed lasers: holmium (Ho): yttrium‐aluminium‐garnet (YAG), thulium fiber laser (TFL), and pulsed thulium (p‐Tm):YAG.Materials and MethodsA 150‐W Ho:YAG, a 60‐W TFL, and a 100‐W p‐Tm:YAG lasers were compared. The laser settings that can
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External validation of an artificial intelligence model for Gleason grading of prostate cancer on prostatectomy specimens BJU Int. (IF 3.7) Pub Date : 2024-07-11 Bogdana Schmidt, Simon John Christoph Soerensen, Hriday P. Bhambhvani, Richard E. Fan, Indrani Bhattacharya, Moon Hyung Choi, Christian A. Kunder, Chia‐Sui Kao, John Higgins, Mirabela Rusu, Geoffrey A. Sonn
ObjectivesTo externally validate the performance of the DeepDx Prostate artificial intelligence (AI) algorithm (Deep Bio Inc., Seoul, South Korea) for Gleason grading on whole‐mount prostate histopathology, considering potential variations observed when applying AI models trained on biopsy samples to radical prostatectomy (RP) specimens due to inherent differences in tissue representation and sample
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Complications of vasectomy: results from a prospective audit of 105 393 procedures BJU Int. (IF 3.7) Pub Date : 2024-07-11 Julian Peacock, Gareth James, Melanie Atkinson, John Henderson
ObjectivesTo provide up‐to‐date complication rates for vasectomy in the UK using 15 years of data collected by the Association of Surgeons in Primary Care (ASPC).Patients and MethodsData were collected between 2007 and March 2022. A patient questionnaire was completed on the day of surgery and at 4 months postoperatively. Rates of early and late failure, infection, hospital admission or re‐admission
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Congenital hydronephrosis. Assessing indications for surgery and follow‐up. Still an enigma? BJU Int. (IF 3.7) Pub Date : 2024-07-10 Jens Christian Djurhuus, Lars Henning Olsen
In a study by Gharpure et al. [1], the authors propose a new morphological parameter potentially useful for evaluating and following up surgical intervention for congenital hydronephrosis. One parameter in a long row of presented methods regarding how hydronephrosis should be characterised. Osborne et al. [2] introduced intravenous urography using a sodium iodide solution a century ago. Since then
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Impact of homologous recombination repair/BReast CAncer (BRCA) gene alterations on survival in a real‐world setting of metastatic prostate cancer BJU Int. (IF 3.7) Pub Date : 2024-07-10 Mike Wenzel, Benedikt Hoeh, Florestan Koll, Clara Humke, Anne Fassl, Henning Reis, Peter Wild, Thomas Steuber, Markus Graefen, Derya Tilki, Miriam Traumann, Severine Banek, Felix K.H. Chun, Philipp Mandel
ObjectiveTo investigate alterations of homologous recombination repair (HRR) and especially BReast CAncer 1/2 (BRCA1/2) gene on overall survival (OS). Moreover, to explore the effect of inhibition of poly(ADP‐ribose)‐polymerase (PARPi) as systemic therapy for metastatic castration‐resistant prostate cancer (mCRPC).Patients and methodsOf all HRR‐screened patients with metastatic prostate cancer, baseline
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Mitochondrial dysfunction and NLRP3 inflammasome: key players in kidney stone formation BJU Int. (IF 3.7) Pub Date : 2024-07-05 Boyan Su, YaLin Ren, Weimin Yao, Yue Su, Qiqi He
The mitochondrion serves as a critical intracellular organelle, engaging in essential roles in the regulation of energy production, oxidative stress management, calcium homeostasis, and apoptosis. One such disease that has been particularly associated with these functions is kidney stone disease (KSD), specifically calcium oxalate (CaOx). It is underpinned by oxidative stress and tissue inflammation
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Litigation claims in Urology in the UK National Health Service: an analysis of the trends, costs and causes over a 16‐year period BJU Int. (IF 3.7) Pub Date : 2024-07-05 Abhinav Tiwari, Jenni Lane, Bhaskar Somani
ObjectiveTo analyse the litigation trends and the reasons for claims within the specialty of Urology, within the UK National Health Service (NHS), over a 16‐year period.Materials and MethodsData were requested from NHS Resolution under the Freedom of Information Act 2000. This included the total number of claims in Urology, the number of these that were successful (settled or closed), and the costs
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Primary retroperitoneal lymph node dissection for metastatic non‐seminomatous germ cell tumours: outcomes and adjuvant chemotherapy BJU Int. (IF 3.7) Pub Date : 2024-07-05 Ahmad Mousa, Lynn Anson‐Cartwright, Eshetu G. Atenafu, Michael A.S. Jewett, Philippe Bedard, Di Maria Jiang, Rachel Glicksman, Peter Chung, Padraig Warde, Martin O’Malley, Susan Prendeville, Robert J. Hamilton
ObjectivesTo compare the outcomes and treatment burden of primary retroperitoneal lymph node dissection (pRPLND) alone versus pRPLND + adjuvant chemotherapy (AC) in patients with pathological stage II (PSII) non‐seminomatous germ cell tumours (NSGCT).Patients and MethodsRetrospective review of the Princess Margaret Cancer Center eTestes cancer database identified patients with PSII NSGCT after pRPLND
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Thromboprophylaxis during neoadjuvant chemotherapy for bladder cancer reduces thromboembolism and bleeding BJU Int. (IF 3.7) Pub Date : 2024-07-03 Luca Antonelli, Pedro David Wendel-Garcia, Manja Deforth, Luca Afferi, Costantino Leonardo, Francesco Esperto, Marco Borghesi, Alessandro Antonelli, Karl Tully, Paolo Umari, Simone Albisinni, Andrea Mari, Renate Pichler, Francesco Claps, Jeremy Yuen-Chun Teoh, Mathieu Roumiguié, Gerald Bastian Schulz, Luca Orecchia, Francesco Soria, Morgan Roupret, Gautier Marcq, Cedric Poyet, Majed Alrumayyan, Michael
To assess the risk of venous thromboembolic events (VTEs) and bleeding with or without thromboprophylaxis during neoadjuvant chemotherapy in bladder cancer patients scheduled for radical cystectomy.
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Retzius‐sparing robot‐assisted radical prostatectomy with the Hugo™ robot‐assisted surgery system: feasibility, operative setup and surgical outcomes BJU Int. (IF 3.7) Pub Date : 2024-07-04 Paolo Dell’Oglio, Francesco Chierigo, Valerio Cellini, Stefano Tappero, Alberto Olivero, Ofir Maltzman, Alberto Caviglia, Antonio Piccione, Carlo Buratto, Michele Barbieri, Giancarlo Napoli, Elena Strada, Erika Palagonia, Giovanni Petralia, Silvia Secco, Dario Di Trapani, Aldo Massimo Bocciardi, Antonio Galfano
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Artificial intelligence for detection of prostate cancer in biopsies during active surveillance BJU Int. (IF 3.7) Pub Date : 2024-07-04 Ida Arvidsson, Edvard Svanemur, Felicia Marginean, Athanasios Simoulis, Niels Christian Overgaard, Kalle Åström, Anders Heyden, Agnieszka Krzyzanowska, Anders Bjartell
ObjectivesTo evaluate a cancer detecting artificial intelligence (AI) algorithm on serial biopsies in patients with prostate cancer on active surveillance (AS).Patients and methodsA total of 180 patients in the Prostate Cancer Research International Active Surveillance (PRIAS) cohort were prospectively monitored using pre‐defined criteria. Diagnostic and re‐biopsy slides from 2011 to 2020 (n = 4744)
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A 2‐year prospective evaluation of the Prostate Health Index in guiding biopsy decisions in a large cohort BJU Int. (IF 3.7) Pub Date : 2024-07-04 Peter Ka‐Fung Chiu, Alex Qinyang Liu, Sui‐Yan Lau, Jeremy Yuen‐Chun Teoh, Chi‐Chun Ho, Chi‐Hang Yee, See‐Ming Hou, Chi‐Kwok Chan, Wai‐Lun Tang, Chris H. Bangma, Peggy Sau‐Kwan Chu, Wing‐Tat Poon, Chi‐Fai Ng, Monique J. Roobol
ObjectivesTo prospectively evaluate how the Prostate Health Index (PHI) impacts on clinical decision in a real‐life setting for men with a prostate‐specific antigen (PSA) level between 4 and 10 ng/mL and normal digital rectal examination.Patients and MethodsSince 2016, the PHI has been available at no cost to eligible men in all Hong Kong public hospitals. All eligible patients who received PHI testing
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Impact of frozen section on long‐term outcomes in robot‐assisted laparoscopic prostatectomy BJU Int. (IF 3.7) Pub Date : 2024-07-04 Ned Kinnear, Paul Cotter Fonseca, Catherine Ogbechie, Sana Adam, Omar Haidar, Aromal Jinaraj, Michael O'Callaghan, Samita Agarwal, Tim Lane, Nikhil Vasdev, James Adshead
ObjectivesTo compare 1‐year functional and 5‐year oncological outcomes of men undergoing robot‐assisted laparoscopic prostatectomy (RALP) with neurovascular structure‐adjacent frozen‐section examination (NeuroSAFE) with those in men undergoing RALP without NeuroSAFE (standard of care [SOC]).Subjects and MethodsMen undergoing RALP in our centre between 1 January 2009 and 30 June 2018 were enrolled from
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Association of Genomic Prostate Score at positive margin with recurrence after radical prostatectomy BJU Int. (IF 3.7) Pub Date : 2024-07-02 Sanaz Nourmohammadi Abadchi, Daniela C. Salles, Cynthia Flannery, Varun Sama, Frederick L. Baehner, Joao P. Zambon, Adrianna A. Mendes, Lia DePaula Oliveira, Misop Han, Yuezhou Jing, Alan W. Partin, Bruce J. Trock, Tamara L. Lotan
ObjectivesTo evaluate the utility of the 17‐gene Genomic Prostate Score® (GPS; MDxHealth, Irvine, CA, USA) performed on prostate cancer at the positive margin of the radical prostatectomy (RP) for its association with risk of subsequent biochemical recurrence (BCR).Patients and MethodsWe designed a case‐cohort for the outcome of BCR, selecting 223 from a cohort of 813 RP patients treated at Johns Hopkins
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Assessing risk of lymph node invasion in complete responders to neoadjuvant chemotherapy for muscle-invasive bladder cancer BJU Int. (IF 3.7) Pub Date : 2024-06-24 Rocco Simone Flammia, Gabriele Tuderti, Eugenio Bologna, Antonio Minore, Flavia Proietti, Leslie Claire Licari, Riccardo Mastroianni, Umberto Anceschi, Aldo Brassetti, Alfredo Bove, Leonardo Misuraca, Simone D'Annunzio, Maria Consiglia Ferriero, Salvatore Guaglianone, Giuseppe Chiacchio, Cosimo De Nunzio, Costantino Leonardo, Giuseppe Simone
To investigate the lymph node invasion (LNI) rate in patients exhibiting complete pathological response (CR) to neoadjuvant chemotherapy (NAC) and to test the association of CR status with lower LNI and better survival outcomes.
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Targeted Investigational Treatment Analysis of Novel Anti‐androgen (TITAN) study: ultralow prostate‐specific antigen decline with apalutamide plus androgen‐deprivation therapy BJU Int. (IF 3.7) Pub Date : 2024-06-28 Axel S. Merseburger, Neeraj Agarwal, Anders Bjartell, Hirotsugu Uemura, Alvaro Juarez Soto, Amitabha Bhaumik, Jürgen Böhm, Nguyen Tran, Nils Krochmann, Mehregan Nematian‐Samani, Suneel D. Mundle, Sabine D. Brookman‐May, Angela Lopez‐Gitlitz, Sharon A. McCarthy, Kim Chi, Simon Chowdhury
ObjectiveTo assess the association between achievement of prostate‐specific antigen (PSA) levels ≤0.2 ng/mL (henceforth ‘ultralow’) and clinical outcomes in patients in the ‘Targeted Investigational Treatment Analysis of Novel Anti‐androgen’ (TITAN) study (ClinicalTrials.gov Identifier NCT02489318) with metastatic castration‐sensitive prostate cancer (mCSPC).Patients and MethodsPatients in the TITAN
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Perspectives on technology: Prostate Imaging‐Reporting and Data System (PI‐RADS) interobserver variability BJU Int. (IF 3.7) Pub Date : 2024-06-26 Michio Taya, Spencer C. Behr, Antonio C. Westphalen
ObjectivesTo explore the topic of Prostate Imaging‐Reporting and Data System (PI‐RADS) interobserver variability, including a discussion of major sources, mitigation approaches, and future directions.MethodsA narrative review of PI‐RADS interobserver variability.ResultsPI‐RADS was developed in 2012 to set technical standards for prostate magnetic resonance imaging (MRI), reduce interobserver variability
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Total bulbospongiosum muscle sparing for bulbar urethroplasty: beyond the one‐sided dissection BJU Int. (IF 3.7) Pub Date : 2024-06-25 Pankaj Joshi, Nicole Albanese, Shreyas Bhadranawar, Francesco Cattafi, Andrea Salonia, Francesco Montorsi, Sanjay Kulkarni, Marco Bandini
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Preliminary findings on vitamin D 25‐OH levels in urine analysis: implications for clinical practice BJU Int. (IF 3.7) Pub Date : 2024-06-25 Andrea Piccolini, Fabio Grizzi, Marta Monari, Mohamed A.A.A. Hegazi, Nicolò Maria Buffi, Paolo Casale, Vittorio Fasulo, Stefano Moretto, Ludovica Cella, Paolo Vota, Giovanni Toia, Cinzia Mazzieri, Riccardo Galli, Paola Petrillo, Paola Morelli, Anna Cantisani, Chiara Bonavolontà, Caterina Scordamaglia, Ilaria Cannone, Nadine Veronese, Alex Villa, Giuseppe Ossolengo, Enrico Marsili, Gianluigi Taverna
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Adeno‐associated virus‐based gene therapy for cystinuria BJU Int. (IF 3.7) Pub Date : 2024-06-25 Dazhou Liao, Xianyanling Yi, Yunjin Bai, Yang Yang, Jianzhong Ai
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Real‐world performance of Uromonitor® in urothelial bladder cancer detection: a multicentric trial BJU Int. (IF 3.7) Pub Date : 2024-06-25 Ingmar Wolff, Anton P. Kravchuk, Ralph M. Wirtz, Thorsten Schlomm, Anja Rabien, Dezhi Rong, Sebastian L. Hofbauer, Flora K. Labonté, Dimitri Barski, Thomas Otto, Andreas Gössl, Sabine D. Brookman‐May, Christian P. Gilfrich, Thorsten H. Ecke, Matthias May
ObjectivesTo compare Uromonitor® (U‐Monitor Lda, Porto, Portugal), a multitarget DNA assay that detects mutated proto‐oncogenes (telomerase reverse transcriptase [TERT], fibroblast growth factor receptor 3 [FGFR‐3], Kirsten rat sarcoma viral oncogene homologue [KRAS]), with urine cytology in the urine‐based diagnosis of urothelial carcinoma of the bladder (UCB) within a multicentre real‐world setting
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Trophoblast cell surface antigen‐2: a promising new biomarker and potential therapeutic target in penile squamous cell carcinoma BJU Int. (IF 3.7) Pub Date : 2024-06-20 Richard Weiten, Enno Storz, Carolina Kessler, Laurenz Sperber, Hanna Elisa Spohn, David Pfister, Tim Nestler, Yuri Tolkach, Friederike Linden, Ralph Wirtz, Melanie von Brandenstein, Philipp Krausewitz, Axel Heidenreich
ObjectiveTo evaluate the potential utility of antibody‐drug conjugates targeting trophoblast cell surface antigen‐2 (TROP‐2) in patients with primary penile squamous cell carcinoma (PSCC), patients with recurrence (REC cohort), and patient‐matched distant metastases (MET cohort), and to assess the potential use of TROP‐2 as a predictive non‐invasive biomarker in PSCC.MethodsA cohort comprising a PRIM
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Evaluation of margins during radical prostatectomy: confocal microscopy vs frozen section analysis BJU Int. (IF 3.7) Pub Date : 2024-06-18 Gennaro Musi, Francesco A. Mistretta, Mariia Ivanova, Ottavio de Cobelli, Andrea Bellin, Gianluca Gaetano Vago, Gabriella Pravettoni, Oriana Pala, Daniela Lepanto, Danilo Bottero, Mattia Luca Piccinelli, Matteo Tallini, Giulia Marvaso, Matteo Ferro, Giuseppe Petralia, Barbara Alicja Jereczek-Fossa, Nicola Fusco, Giuseppe Renne, Stefano Luzzago
To test the performance of ex vivo fluorescence confocal microscopy (FCM; Vivascope 2500M-G4), as compared to intra-operative frozen section (IFS) analysis, to evaluate surgical margins during robot-assisted radical prostatectomy (RARP), with final pathology as the reference standard.
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The microbiota in patients with interstitial cystitis/bladder pain syndrome: a systematic review BJU Int. (IF 3.7) Pub Date : 2024-06-18 Chaowei Fu, Yuwei Zhang, Linghui Liang, Hao Lin, Kai Shan, Fengping Liu, Ninghan Feng
To comprehensively review and critically assess the literature on microbiota differences between patients with interstitial cystitis (IC)/bladder pain syndrome (BPS) and normal controls and to provide clinical practice guidelines.
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Outcomes of active surveillance for Japanese patients with prostate cancer (PRIAS-JAPAN) BJU Int. (IF 3.7) Pub Date : 2024-06-17 Takuma Kato, Ryuji Matsumoto, Akira Yokomizo, Yoichiro Tohi, Hiroshi Fukuhara, Yoichi Fujii, Keiichiro Mori, Takuma Sato, Junichi Inokuchi, Katsuyoshi Hashine, Shinichi Sakamoto, Hidefumi Kinoshita, Koji Inoue, Toshiki Tanikawa, Takanobu Utsumi, Takayuki Goto, Isao Hara, Hiroshi Okuno, Yoshiyuki Kakehi, Mikio Sugimoto
To report the outcomes of repeat biopsies, metastasis and survival in the Prostate Cancer Research International: Active Surveillance (PRIAS)-JAPAN study, a prospective observational study for Japanese patients, initiated in 2010.
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Body morphometry may predict parastomal hernia following radical cystectomy with ileal conduit BJU Int. (IF 3.7) Pub Date : 2024-06-17 Zaeem Lone, David Shin, Amy Nowacki, Rebecca A. Campbell, Eiftu Haile, Andrew Wood, Kyle Harris, Ryan Ellis, Mohammed Eltemamy, Samuel C. Haywood, Jihad Kaouk, Steven C. Campbell, Christopher J. Weight, Georges-Pascal Haber, Benjamin Miller, Clayton Petro, Lucas Beffa, Ajita Prabhu, Michael Rosen, Erick M. Remer, Nima Almassi
To investigate whether preoperative body morphometry analysis can identify patients at risk of parastomal hernia (PH), which is a common complication after radical cystectomy (RC).
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The psychosocial impact of prostate cancer screening for BRCA1 and BRCA2 carriers BJU Int. (IF 3.7) Pub Date : 2024-06-05 Elizabeth K. Bancroft, Elizabeth C. Page, Mark N. Brook, Jennifer Pope, Sarah Thomas, Kathryn Myhill, Brian T. Helfand, Pooja Talaty, Kai-Ren Ong, Emma Douglas, Jackie Cook, Derek J. Rosario, Monica Salinas, Saundra S. Buys, Jo Anson, Rosemarie Davidson, Mark Longmuir, Lucy Side, Diana M. Eccles, Marc Tischkowitz, Amy Taylor, Mara Cruellas, Eduard Perez Ballestero, Ruth Cleaver, Mohini Varughese, Julian
To report the long-term outcomes from a longitudinal psychosocial study that forms part of the ‘Identification of Men with a genetic predisposition to ProstAte Cancer: Targeted Screening in men at higher genetic risk and controls’ (IMPACT) study. The IMPACT study is a multi-national study of targeted prostate cancer (PrCa) screening in individuals with a known germline pathogenic variant (GPV) in either
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A new technique for the treatment of ureteric stricture after kidney transplantation BJU Int. (IF 3.7) Pub Date : 2024-06-04 Xiaoshuai Gao, Wei Wang, Fei Li, Liao Peng, Xingpeng Di, Jixiang Chen, Xin Wei
To evaluate the safety and effectiveness of endoscopic treatments with Allium® metal ureteric stent (AMUS) for ureteric strictures after kidney transplantation (KT).
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A phase II trial of apalutamide for intermediate-risk prostate cancer and molecular correlates BJU Int. (IF 3.7) Pub Date : 2024-06-04 Andrew W. Hahn, Ganiraju C. Manyam, Brian F. Chapin, Miao Zhang, Yao Yu, Curtis A. Pettaway, Lisly Chery, Louis L. Pisters, John F. Ward, Justin R. Gregg, John Papadopoulos, Ashish M. Kamat, Marisa Lozano, Anh Hoang, Bradley Broom, Xuemei Wang, Chad D. Huff, Christopher J. Logothetis, Patricia Troncoso, Patrick G. Pilié, John W. Davis
To determine whether 6 months of preoperative apalutamide for intermediate-risk prostate cancer (IRPCa) reduces the aggregate postoperative radiotherapy risk and to evaluate associations of molecular perturbations with clinical outcomes in this study cohort.
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International consensus panel for transurethral resection of bladder tumours metrics: assessment of face and content validity BJU Int. (IF 3.7) Pub Date : 2024-06-03 Marco Paciotti, Pietro Diana, Andrea Gallioli, Ruben De Groote, Rui Farinha, Vincenzo Ficarra, Richard Gaston, Paolo Gontero, Rodolfo Hurle, Luis Martínez-Piñeiro, Andrea Minervini, Vito Pansadoro, Ben Van Cleynenbreugel, Peter Wiklund, Paolo Casale, Giovanni Lughezzani, Alessandro Uleri, Alexandre Mottrie, Joan Palou, Anthony G. Gallagher, Alberto Breda, Nicolò Buffi
To develop performance metrics that objectively define a reference approach to a transurethral resection of bladder tumours (TURBT) procedure, seek consensus on the performance metrics from a group of international experts.
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Analgesic efficacy of rectus sheath catheter is non‐inferior to thoracic epidural catheter BJU Int. (IF 3.7) Pub Date : 2024-06-01 Raymond Tang, Edmund Charles Paul Chedgy, Alan I. So
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Perspectives on technology: urethral slings in a post‐mesh world BJU Int. (IF 3.7) Pub Date : 2024-06-01 Cindy Garcia, David Homewood, Johan Gani, Helen E. O'Connell
ObjectivesTo detail the history of synthetic mid‐urethral slings (SMUSs) and fascial slings, their efficacy, associated complications, and changes to practice that have occurred after the issuing of the 2011 US Food and Drug Administration (FDA) Safety Communication statement on transvaginal mesh (TVM), and to highlight the need for surgical registries and high‐quality randomised controlled data to
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Precise treatment of pelvic fracture urethral injury associated with urethrorectal fistula BJU Int. (IF 3.7) Pub Date : 2024-05-31 Lin Wang, Wenxiong Song, Rong Lv, Chongrui Jin, Zhuo Zhang, Chao Li, Yinglong Sa, Yidong Liu, Xiangguo Lv
ObjectiveTo evaluate the effect of a new strategy of transperineal anastomotic urethroplasty (TAU) with proximal transection in treating pelvic fracture urethral injury (PFUI) associated with urethrorectal fistula (URF).Patients and MethodsA retrospective review of all patients treated by TAU with proximal transection and fistula repair for PFUI associated with URF was performed between August 2013
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Quality‐of‐life outcomes of the ROBOtic‐assisted versus Conventional Open Partial nephrectomy (ROBOCOP) II trial BJU Int. (IF 3.7) Pub Date : 2024-05-31 Marie Angela Sidoti Abate, Hanna Saskia Menold, Manuel Neuberger, Marietta Kirchner, Caelan Max Haney, Philipp Nuhn, Niklas Westhoff, Patrick Honeck, Maurice‐Stephan Michel, Maximilian Christian Kriegmair, Karl‐Friedrich Kowalewski
ObjectivesTo comprehensively compare quality‐of‐life (QoL) outcomes between open partial nephrectomy (OPN) and robot‐assisted PN (RAPN) from the randomised ROBOtic‐assisted versus Conventional Open Partial nephrectomy (ROBOCOP) II trial, as QoL data comparing OPN and RAPN are virtually non‐existent, especially not from randomised controlled trials (RCTs).Patients and MethodsThe ROBOCOP II was a single‐centre
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A collaborative review of the microsatellite instability/deficient mismatch repair phenotype in patients with upper tract urothelial carcinoma BJU Int. (IF 3.7) Pub Date : 2024-05-30 Pierre‐Etienne Gabriel, Géraldine Cancel‐Tassin, François Audenet, Alexandra Masson‐Lecomte, Yves Allory, Mathieu Roumiguié, Benjamin Pradère, Yohann Loriot, Priscilla Léon, Olivier Traxer, Evanguelos Xylinas, Morgan Rouprêt, Yann Neuzillet, Thomas Seisen
ObjectiveTo perform a collaborative review of the literature exploring the microsatellite instability/deficient mismatch repair (MSI/dMMR) phenotype in patients with upper tract urothelial carcinoma (UTUC).MethodA collaborative review of the literature available on Medline was conducted by the Cancer Committee of the French Association of Urology to report studies describing the genetic mechanisms
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Differential renal length index: useful measure in management of isolated unilateral hydronephrosis? BJU Int. (IF 3.7) Pub Date : 2024-05-30 Ketaki Gharpure, Sara Lobo, Meghana Bandaru, Navroop Johal, Katrien Verveckken, Karen de Baets, Koen van Hoeck, Gunter DeWin, Abraham Cherian
ObjectiveTo explore the usefulness of the ‘differential renal length index’ (iDRL) before and after pyeloplasty, as the anteroposterior diameter is commonly used to quantify hydronephrosis but inaccuracies arise due to interobserver variability, hydration status and pure intra‐renal dilatation.Patients and MethodsProspectively collected data, from two centres, of all children undergoing pyeloplasty
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Holmium:yttrium‐aluminium‐garnet laser with MOSES technology is more efficient than thulium fibre laser in supine mini‐percutaneous nephrolithotomy BJU Int. (IF 3.7) Pub Date : 2024-05-27 Lucas B. Vergamini, Willian Ito, Nicholas Choi B, Holly E. Du, Mihaela E. Sardiu, Donald Neff, David A. Duchene, Wilson R. Molina, Bristol B. Whiles
ObjectivesTo address the paucity of literature comparing outcomes achieved with utilisation of the high‐power holmium:yttrium‐aluminium‐garnet (Ho:YAG) laser with MOSES technology vs those achieved with the thulium fibre laser (TFL) in mini‐percutaneous nephrolithotomy (PCNL).MethodsA retrospective review was performed of patients undergoing supine mini‐PCNL between August 2021 and May 2023. Exclusion
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British Association of Urological Surgeons Consensus statements on the management of ketamine uropathy BJU Int. (IF 3.7) Pub Date : 2024-05-22 Mohammed Belal, Alison Downey, Ruth Doherty, Ased Ali, Hashim Hashim, Andy Kozan, Magda Kujawa, Mahreen Pakzad, Tina Rashid, Nadir Osman, Arun Sahai, Suzanne Biers
To provide guidance in the form of consensus statement in the management of ketamine uropathy.
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Recovery and immune function after low pressure pneumoperitoneum during robot‐assisted radical prostatectomy: a randomised controlled trial BJU Int. (IF 3.7) Pub Date : 2024-05-24 Gabby T. J. A. Reijnders‐Boerboom, Lotte M. C. Jacobs, Leonie S. Helder, Ivo F. Panhuizen, Maik P. J. Brouwer, Kim I. Albers, Tom Loonen, Gert Jan Scheffer, Christiaan Keijzer, Jean‐Paul A. van Basten, Michiel C. Warlé
ObjectiveTo compare the effectiveness of low intra‐abdominal pressure (IAP) facilitated by deep neuromuscular block (NMB) to standard practice in improving the quality of recovery, preserving immune function, and enhancing parietal perfusion during robot‐assisted radical prostatectomy (RARP).Patients and MethodsIn this blinded, randomised controlled trial, 96 patients were randomised to the experimental
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Case of the month from the Radiotherapy Unit, Department of Medical and Surgical Sciences, University of Bologna, Italy: breaking boundaries beyond five lesions with multifocal stereotactic radiotherapy in prostate cancer BJU Int. (IF 3.7) Pub Date : 2024-05-22 Erika Galietta, Silvia Strolin, Elisa Lodi‐Rizzini, Paolo Castellucci, Savino Cilla, Milly Buwenge, Maria Vadala’, Stefano Fanti, Maria Ntreta, Lidia Strigari, Alessio G. Morganti
Introduction Stereotactic body radiotherapy (SBRT), characterised by its precise and focused delivery of high doses of radiation to well-defined targets, has emerged as an effective treatment modality for oligometastatic prostate cancer (PCa). Traditionally applied to patients with a limited number of metastases (≤5) [1], SBRT offers targeted therapeutic benefits. In this case study, we present an
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Assessing long‐term upgrade risks in recurrent low‐grade non‐muscle‐invasive bladder cancer, can we deintensify the treatment? BJU Int. (IF 3.7) Pub Date : 2024-05-22 Alesio Finocchiaro, Marco Paciotti, Roberto Contieri, Vittorio Fasulo, Alberto Saita, Giovanni Lughezzani, Nicolo Maria Buffi, Massimo Lazzeri, Rodolfo Hurle, Paolo Casale
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Determining the optimal fill volume for fluid‐filled testicular prostheses – less is more BJU Int. (IF 3.7) Pub Date : 2024-05-21 Georges Mehawed, Rebecca Murray, Kevin Wang, Matthew J. Roberts, Nicholas J. Rukin
Testicular loss or absence can present for a range of reasons including congenital absence of testis to orchidectomy. Men undergo orchidectomy for numerous reasons including testicular cancer, cryptorchidism, and chronic orchialgia. In 2020, 74 500 men were diagnosed with testicular cancer globally leading to a potential significant role for testicular prostheses [1]. Although under-utilised, testicular
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Case of the month from the Department of Medical Oncology, Peter MacCallum Cancer Centre, University of Melbourne, Australia: recurrent metastatic spermatocytic tumour successfully treated with salvage systemic chemotherapy BJU Int. (IF 3.7) Pub Date : 2024-05-15 Jane McKenzie, Catherine Mitchell, Jeremy Lewin, Ciara Conduit
Introduction Spermatocytic tumours are a rare subtype of testicular neoplasm and represent less than 1% of all testicular neoplasms. They generally display indolent biology and therefore commonly present as large testicular masses. Despite this, and in contrast to invasive germ cell tumours, spermatocytic tumours are rarely pT2 (i.e., rarely involve the tunica vaginalis or display lymphovascular invasion)
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Grid‐based cognitive diagnostic prostatic biopsy without transrectal ultrasonography BJU Int. (IF 3.7) Pub Date : 2024-05-14 Dhruv Satya Sahni, John Morrison, Hing Y. Leung
Introduction Prostate and colorectal cancers are the second and third most common malignancies affecting men globally [1]. Abdominoperineal resection is the standard of care surgical treatment for patients with malignancy of the distal rectum or anal canal, while pan-proctocolectomy may be indicated for patients with inflammatory bowel disease and familial adenomatous polyposis [2]. Both these procedures
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A review of vitamin use for the prevention or treatment of prostate cancer BJU Int. (IF 3.7) Pub Date : 2024-05-14 David J. Benjamin, Omid Yazdanpanah, Arash Rezazadeh Kalebasty
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Targeted microwave ablation for prostate cancer (FOSTINE1b): a prospective ‘ablate‐and‐resect’ study BJU Int. (IF 3.7) Pub Date : 2024-05-14 Alexandre Peltier, Roland van Velthoven, Arthur Baudewyns, Grégoire Assenmacher, Marc Lemort, Yolene Lefebvre, Nicolas Sirtaine, Romain Diamand
ObjectiveTo assess histopathological outcomes, as well as feasibility and safety of targeted microwave ablation (TMA) via the Trinity® system (KOELIS, La Tronche, France).Patients and methodsProspective, single‐institution, interventional Phase IIa study with an ‘ablate‐and‐resect’ design. In all, 11 patients diagnosed with localised prostate cancer (PCa) underwent TMA via the Trinity system under
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Transnational telesurgery performed with the new robot‐assisted flexible ureteroscopy system BJU Int. (IF 3.7) Pub Date : 2024-05-11 Guangdi Chu, Xuecheng Yang, Wei Jiao, Jianchang Zhao, Bo Guan, Yuan Gao, Shuxin Wang, Jianmin Li, Haitao Niu
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Female non‐obstetric urogenital fistula repair: long‐term patient‐reported outcomes and a scoping literature review BJU Int. (IF 3.7) Pub Date : 2024-05-11 Jakob Klemm, Daniel R. Stelzl, Robert J. Schulz, Phillip Marks, Shahrokh F. Shariat, Margit Fisch, Roland Dahlem, Malte W. Vetterlein
ObjectiveTo investigate long‐term and patient‐reported outcomes, including sexual function, in women undergoing urogenital fistula (UGF) repair, addressing the lack of such data in Western countries, where fistulas often result from iatrogenic causes.Patients and MethodsWe conducted a retrospective analysis at a tertiary referral centre (2010–2023), classifying fistulas based on World Health Organisation