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Metastatic risk in clear cell renal cell carcinoma: a tool incorporating sex, size, and grade BJU Int. (IF 3.7) Pub Date : 2024-12-19 Frederik F. Thomsen, Marcus Westerberg, Rasmus D. Petersson, Rasmine Bak, Julie Bak Lindholst, Hayder Al-Husseinawi, Emma Heeno, Nessn H. Azawi
To identify predictors of metastases, estimate the proportion of metastatic clear cell renal cell carcinoma (ccRCC) cases according to these predictors, and subsequently create a risk table showing the absolute difference in metastasis proportion for each 10 mm increase in tumour size.
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Sharing surgical images on social media: a snapshot of practices and some reflections for improvement BJU Int. (IF 3.7) Pub Date : 2024-12-16 Patrick Juliebø‐Jones, Vineet Gauhar, Ali Talyshinskii, Christian Arvei Moen, Ingunn Roth, Lazaros Tzelves, Christian Beisland, Bhaskar K Somani
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Impact of patient positioning during surgery on neuropathies after robot‐assisted laparoscopic radical prostatectomy: a randomised controlled trial BJU Int. (IF 3.7) Pub Date : 2024-12-13 Nico Christian Grossmann, Fabian Joel Aschwanden, Julian Cornelius, Christian Malkmus, Leutrim Zahiti, Pascal Viktorin, Lea Fierley, Einar Wilder‐Smith, Philipp Baumeister, Agostino Mattei, Christian Daniel Fankhauser
ObjectiveTo investigate whether ankle braces or shoulder support used for fixation during robot‐assisted radical prostatectomy (RARP), where patients are commonly positioned in the head‐down Trendelenburg position, differ in their potential to cause peripheral nerve injury.Patients and MethodsA prospective, double‐blind, randomised controlled trial was conducted on patients undergoing RARP for prostate
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Primary retroperitoneal lymph node dissection in clinical stage 2a/b non-seminomatous germ cell tumour BJU Int. (IF 3.7) Pub Date : 2024-12-11 Luca Antonelli, Axel Heidenreich, Aditya Bagrodia, Armon Amini, Fady Baky, Nicolas Branger, Walter Cazzaniga, Timothy N. Clinton, Siamak Daneshmand, Hooman Djaladat, Scott Eggener, Alireza Ghoreifi, Robert J. Hamilton, Matthew Ho, Wade J. Sexton, Sebastiano Nazzani, David Nicol, Nicola Nicolai, Kathleen Olson, Pia Paffenholz, James Porter, Zhiyu Qian, Nicholas R. Rocco, Anirudh Yerrapragada, Sean P
To reassess the role of primary retroperitoneal lymph node dissection (RPLND) in patients with marker-negative non-seminomatous germ cell tumour (NSGCT) clinical stage (CS) 2a, to explore results in patients with CS 2b and to evaluate surgical methods, recurrence, and adjuvant chemotherapy indications.
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Survival after trimodal therapy in octogenarians with organ‐confined urothelial bladder cancer BJU Int. (IF 3.7) Pub Date : 2024-12-12 Mattia Longoni, Francesco Di Bello, Natali Rodriguez Peñaranda, Fabian Falkenbach, Andrea Marmiroli, Quynh Chi Le, Zhe Tian, Jordan A. Goyal, Nicola Longo, Salvatore Micali, Markus Graefen, Gennaro Musi, Felix K. H. Chun, Fred Saad, Shahrokh F. Shariat, Marco Moschini, Giorgio Gandaglia, Francesco Montorsi, Alberto Briganti, Pierre I. Karakiewicz
ObjectivesIt is not known whether cancer‐specific mortality (CSM) differences distinguish radical cystectomy (RC) from trimodal therapy (TMT) in octogenarians harbouring organ‐confined (T2N0M0) urothelial cancer of the urinary bladder (UCUB).MethodsWithin the Surveillance, Epidemiology, and End Results database (2004–2021), CSM and other‐cause mortality (OCM) rates were computed in octogenarian patients
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The impact of post‐nephroureterectomy surgically induced chronic kidney disease on survival outcomes BJU Int. (IF 3.7) Pub Date : 2024-12-12 Dhruv Puri, Margaret F. Meagher, Zhenjie Wu, Antonio Franco, Linhui Wang, Vitaly Margulis, Raj Bhanvadia, Firas Abdollah, Marco Finati, Alessandro Antonelli, Francesco Ditonno, Nirmish Singla, Stephan Broenimann, Giuseppe Simone, Gabriele Tuderti, Soroush Rais‐Bahrami, Sol C. Moon, Matteo Ferro, Marco Tozzi, Francesco Porpiglia, Daniele Amparore, Andreas Correa, Emma Helstrom, Mark L. Gonzalgo, Dinno
ObjectiveTo investigate the prevalence, predictors and impact of surgically induced chronic kidney disease (CKD‐S) on survival outcomes in patients with upper tract urothelial carcinoma (UTUC) following radical nephroureterectomy (RNU).MethodsUtilising the ROBUUST 2.0 registry, a multicentre retrospective analysis was conducted in patients with UTUC undergoing RNU between 2006 and 2022 who did not
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The role of social media in education: how to maximise learning BJU Int. (IF 3.7) Pub Date : 2024-12-12 Thomas Hughes, Bhaskar K Somani
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New findings regarding predictors of Poor Corporal Integrity in Penile Implant Recipients: A Multicenter International Invesigation BJU Int. (IF 3.7) Pub Date : 2024-12-11 Chrystal Chang, David W. Barham, Zafardjan Dalimov, Daniel Swerdloff, Hossein Sadeghi‐Nejad, Robert Andrianne, Maxime Sempels, Tung‐Chin Hsieh, Georgios Hatzichristodoulou, Muhammed Hammad, Jake Miller, Daniar Osmonov, Aaron Lentz, Paul Perito, Alfredo Suarez‐Sarmiento, James Hotaling, Kelli Gross, James M Jones, Koenraad van Renterghem, Sung Hun Park, Jonathan N. Warner, Matthew Ziegelmann, Vaibhav
ObjectivesTo evaluate the pre‐ and intraoperative variables that impact the integrity of the corporal bodies over time after inflatable penile prosthesis (IPP) placement, as predictors of intraoperative corporal perforation and delayed cylinder complications have not been well characterized.Patients and MethodsWe retrospectively reviewed a 16‐centre multi‐institutional database of IPP surgeries performed
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Sarcopenia may increase cisplatin toxicity in bladder cancer patients with borderline renal function BJU Int. (IF 3.7) Pub Date : 2024-12-10 Eiftu S. Haile, Zaeem Lone, David Shin, Amy S. Nowacki, Nicolas Soputro, Kyle Harris, Rebecca A. Campbell, Andrew Wood, Samuel C. Haywood, Mohamed Eltemamy, Georges‐Pascal Haber, Christopher J. Weight, Hadley M. Wood, Jonathan J. Taliercio, Amanda Nizam, Shilpa Gupta, Erick M. Remer, Nima Almassi
ObjectivesTo assess whether the effect of sarcopenia on neoadjuvant chemotherapy (NAC) toxicity is modified by borderline renal function (estimated glomerular filtration rate [eGFR] 40–65 mL/min) and whether sarcopenia and borderline renal function are independently associated with NAC toxicity risk.Patients and MethodsAll patients with muscle‐invasive bladder cancer (MIBC) who underwent radical cystectomy
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Novel bioabsorbable, low‐dose rate brachytherapy device (CivaSheet®) with radical prostatectomy and adjuvant external beam radiation for the management of prostate cancer BJU Int. (IF 3.7) Pub Date : 2024-12-10 Kennedy E. Okhawere, Shirin Razdan, Alp Tuna Beksac, Indu Saini, Laura Zuluaga, Kirolos Meilika, Burak Ucpinar, Ren‐Dih Sheu, Reza Mehrazin, John Sfakianos, Ashutosh Tewari, Richard G. Stock, Ketan Badani
ObjectiveTo investigate the safety and cancer control of a novel bioabsorbable, low‐dose rate brachytherapy device, CivaSheet® (CivaTech Oncology Inc., Durham, NC, USA), in combination with radical prostatectomy (RP) with or without adjuvant external beam radiation therapy (EBRT) for the management of prostate cancer (PCa).Patients and MethodsThis is an initial, single‐centre experience, two‐dose level
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A Prostate Imaging‐Reporting and Data System version 2.1‐based predictive model for clinically significant prostate cancer diagnosis BJU Int. (IF 3.7) Pub Date : 2024-12-10 David G. Gelikman, William S. Azar, Enis C. Yilmaz, Yue Lin, Luke A. Shumaker, Andrew M. Fang, Stephanie A. Harmon, Erich P. Huang, Sahil H. Parikh, Jason A. Hyman, Kyle Schuppe, Jeffrey W. Nix, Samuel J. Galgano, Maria J. Merino, Peter L. Choyke, Sandeep Gurram, Bradford J. Wood, Soroush Rais‐Bahrami, Peter A. Pinto, Baris Turkbey
ObjectivesTo develop and validate a Prostate Imaging‐Reporting and Data System (PI‐RADS) version 2.1 (v2.1)‐based predictive model for diagnosis of clinically significant prostate cancer (csPCa), integrating clinical and multiparametric magnetic resonance imaging (mpMRI) data, and compare its performance with existing models.Patients and MethodsWe retrospectively analysed data from patients who underwent
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Diagnostic and prognostic genomic aberrations in upper tract urothelial carcinoma can be identified in focal barbotage samples BJU Int. (IF 3.7) Pub Date : 2024-12-10 Tomas Andri Axelsson, Filip Sydén, Jesper Eisfeldt, Ylva Eriksson, Gustav Göthner Lundberg, Georg Jaremko, Ollanta Cuba Gyllensten, Emma Tham, Marianne Brehmer
ObjectivesTo investigate whether genetic analysis of focal barbotage samples obtained at ureterorenoscopy (URS) is possible, and to identify genetic aberrations that might add prognostic information.MethodsThis prospective study included barbotage samples from 42 patients with upper urinary tract urothelial carcinoma (UTUC) confirmed at URS. At URS, focal barbotage specimens were collected for cytology
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January's reviewers of the month BJU Int. (IF 3.7) Pub Date : 2024-12-10
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A comment on: ‘Prevalence of urolithiasis in China: a systematic review and meta‐analysis’ BJU Int. (IF 3.7) Pub Date : 2024-12-10 Rachana Mehta, Ashok Kumar Balaraman, Ganesh Bushi, Sanjit Sah
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The impact of positive surgical margins after cystectomy on oncological outcomes: a nationwide study BJU Int. (IF 3.7) Pub Date : 2024-12-04 Jikke Bosveld, Tri Q. Nguyen, Joost L. Boormans, J. Alfred Witjes, Antoine G. van der Heijden, Niven Mehra, Lambertus A. Kiemeney, Katja K.H. Aben, , Richard P. Meijer, Anke Richters
To evaluate whether surgical margin status, alongside existing postoperative risk indicators, improves the identification of bladder cancer patients who may benefit from adjuvant therapy following radical cystectomy (RC).
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Comparing ambulatory to inpatient percutaneous nephrolithotomy: systematic review and meta‐analysis BJU Int. (IF 3.7) Pub Date : 2024-12-05 Katie Du, Michael Uy, Alan Cheng, Braden Millan, Bobby Shayegan, Edward Matsumoto
ObjectivesTo investigate the differences in perioperative characteristics and postoperative outcomes between inpatient and ambulatory percutaneous nephrolithotomy (PCNL) with a subgroup analysis of same‐day discharge (SDD) patients, summarise published ambulatory pathways and compare cost and satisfaction data.Patients and MethodsThis study was completed according to the Preferred Reporting Items for
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Is there a minimum percentage of sarcomatoid component required to affect outcomes of localised renal cell carcinoma? BJU Int. (IF 3.7) Pub Date : 2024-12-04 Mustafa Soytas, Alice Dragomir, Ghady Bou‐Nehme Sawaya, Charles Hesswani, Maude Tanguay, Antonio Finelli, Lori Wood, Ricardo Rendon, Rahul Bansal, Aly‐Khan Lalani, Daniel Y. C. Heng, Bimal Bhindi, Naveen S. Basappa, Lucas Dean, Alan So, Jasmir G. Nayak, Georg Bjarnason, Rodney Breau, Luke Lavallee, Jean‐Baptiste Lattouf, Frederic Pouliot, Michael Bonert, Simon Tanguay
ObjectiveTo evaluate and compare the outcomes of patients with localised renal cell carcinoma (RCC) with and without sarcomatoid features and the impact of this on cancer recurrence and survival.Material and MethodsThe Canadian Kidney Cancer information system database was used to identify patients diagnosed with localised RCC between January 2011 and December 2022. Patients with pT1‐T3, n Nx‐N0N1
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Telehealth vs face‐to‐face consultations in a urological oncology clinic: a randomised controlled trial BJU Int. (IF 3.7) Pub Date : 2024-12-04 David Armany, Athos Katelaris, Ankur Dhar, Omar Alghazo, Dale Wood, Lawrence H. Kim, Manish I. Patel
ObjectivesTo determine the effectiveness of telehealth, among patients reviewed for urological oncological diseases, compared with standard face‐to‐face (F2F) consultations with regard to patient‐reported satisfaction through use of a validated questionnaire.Materials and MethodsWe conducted a single‐centre randomised controlled trial in 126 patients recruited from the Crown Princess Mary Cancer Centres
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Long‐term quality of life in patients with bladder cancer following radical cystectomy BJU Int. (IF 3.7) Pub Date : 2024-12-01 Emine Akdemir, Martijn M. Stuiver, Maaike W. van de Kamp, Jolanda Bloos ‐ van der Hulst, Laura S. Mertens, Kees Hendricksen, Wim H. van Harten, Anne M. May, Maike G. Sweegers
ObjectivesTo investigate changes in quality of life (QoL) up to 8 years after radical cystectomy (RC) and compare QoL after RC with a gender‐ and age‐matched Dutch normative population. Furthermore, we aimed to identify patient characteristics associated with QoL and QoL trajectories after RC.Patients and MethodsPatients with bladder cancer were invited to complete QoL questionnaires at 3‐month intervals
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In‐field prostate cancer recurrence following radical prostatectomy and salvage radiation BJU Int. (IF 3.7) Pub Date : 2024-11-30 Austin Martin, Ahmed M. Mahmoud, Cameron J. Britton, Anthony Fadel, Mohamed E. Ahmed, Vidit Sharma, Daniel S. Childs, Geoffrey B. Johnson, Brian J. Davis, Lance Mynderse, Derek Lomas, David Woodrum, Daniel Frendl, Jeffrey R. Karnes, Matthew K. Tollefson, Eugene D. Kwon, Jack R. Andrews
ObjectiveTo define the natural history, patterns of recurrence and treatment modalities for local prostate cancer (PCa) recurrence following radical prostatectomy (RP) and radiation therapy (RT), and to investigate factors that could predict metastasis‐free survival (MFS) in this unique patient population.MethodsWe queried a prospectively maintained PCa registry to identify men developing in‐field
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Prolonged ischaemia during partial nephrectomy: impact of warm vs cold BJU Int. (IF 3.7) Pub Date : 2024-11-29 Akira Kazama, Carlos Munoz‐Lopez, Kieran Lewis, Worapat Attawettayanon, Nityam Rathi, Eran Maina, Rebecca A. Campbell, Andrew Wood, Zaeem Lone, Angelica Bartholomew, Jihad Kaouk, Georges‐Pascal Haber, Samuel Haywood, Nima Almassi, Christopher Weight, Jianbo Li, Steven C. Campbell
ObjectiveTo evaluate the impact of prolonged ischaemia during partial nephrectomy (PN), which remains understudied despite its potential clinical relevance.Patients and MethodsOf 1371 patients managed with on‐clamp PN (2011–2014), 759 (55%) had imaging and assessment of serum creatinine levels before and after PN within the appropriate timeframes necessary for inclusion. This timeframe was chosen to
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Association of bi‐parametric MRI measures with continence after robot‐assisted radical prostatectomy BJU Int. (IF 3.7) Pub Date : 2024-11-29 Alexander B. Nolsøe, Vibeke Løgager, Lars Boesen, Peter Busch Østergren, Henrik Jakobsen, Christian Fuglesang S. Jensen, Niels Henrik Bruun, Jens Sønksen, Mikkel Fode
ObjectiveTo investigate the association between pre‐ and postoperative magnetic resonance imaging (MRI) measurements of the membranous urethra and the prostate volume and continence following robot‐assisted radical prostatectomy (RARP).Patients and MethodsFrom December 2018 to June 2022, 100 continent patients undergoing unilateral nerve‐sparing or non‐nerve‐sparing RARP were included in this cohort
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Utility of PSA free‐to‐total ratio for clinically significant prostate cancer in men with a PSA level of <4 ng/mL BJU Int. (IF 3.7) Pub Date : 2024-11-28 Samuel Sii, Nathan Papa, Ting Wai Yiu, Jake Tempo, Liang Qu, Marlon Perera, Ian Thompson, Joseph Ischia, Neil Fleshner, Elliot Smith, Weranja Ranasinghe, Damien Bolton, Dixon T.S. Woon
ObjectiveTo investigate the relationship between the prostate‐specific antigen (PSA) free‐to‐total ratio (FTR) and International Society of Urological Pathology Grade Group ≥2, clinically significant prostate cancer (csPCa) in men with a low PSA level (≤4 ng/mL).Patients and MethodsData were obtained from the Prostate Cancer Prevention Trial. Patients with a PSA level of ≤4 ng/mL and who received a
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Urologist underutilisation of androgen receptor pathway inhibitors for metastatic hormone‐sensitive prostate cancer BJU Int. (IF 3.7) Pub Date : 2024-11-28 Daniel Crisafi, Benjamin Ngie Xiong Wong, Damien Bolton, Joseph Ischia, Dixon Woon
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3D‐printed model for resection of positive surgical margins in robot‐assisted prostatectomy BJU Int. (IF 3.7) Pub Date : 2024-11-27 Christian Engesser, Brantner Philipp, Brigitta Gahl, Walter Matthias, Gehweiler Julian, Helge Seifert, Svetozar Subotic, Cyrill Rentsch, Christian Wetterauer, Lukas Bubendorf, Tatjana Vlajnic, Albolfazl Hosseini, Jan Ebbing
ObjectivesTo improve precision of secondary resection (SR) after positive surgical margin (PSM) detection by frozen section (FS) during nerve‐sparing (NS) robot‐assisted radical prostatectomy (RARP) by employing a personalised three‐dimensional (3D)‐printed prostate model derived from pelvic magnetic resonance imaging (MRI). This model was used to mark positive surgical margins (PSM) and guide intraoperative
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Single‐port extraperitoneal robotic kidney transplantation: early experience of novel technique BJU Int. (IF 3.7) Pub Date : 2024-11-26 Jaya Sai Chavali, Jihad Kaouk, Nicolas Soputro, Mohamed Eltemamy
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Papillary renal cell carcinoma revisited: impact of the World Health Organization 2022 classification on prognostication BJU Int. (IF 3.7) Pub Date : 2024-11-26 Joung Won Sung, Yong Il Lee, Younjuong Kim, Cheryn Song, Ja‐Min Park, Sun Young Yoon, Bokyung Ahn, Yong Mee Cho
ObjectivesTo investigate the impact of the revised papillary renal cell carcinoma (PRCC) classification and evaluate its validity with regard to oncological outcome stratification.Patients and MethodsIdentifying 527 patients with PRCC who underwent surgical resection from 1995 to 2022, a tissue microarray was constructed for immunohistochemical and molecular characterisation. Re‐classification according
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Cystectomy and lymphadenectomy – we now node how far to go! BJU Int. (IF 3.7) Pub Date : 2024-11-21 Jordan Santucci, Sachin Perera, Niranjan Sathianathen, Marlon Perera, Declan Murphy, Nathan Lawrentschuk
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December's reviewers of the month BJU Int. (IF 3.7) Pub Date : 2024-11-19
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Focus on advances in the management of bladder and kidney cancer BJU Int. (IF 3.7) Pub Date : 2024-11-19
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Risk of bleeding after retrograde intrarenal surgery vs miniaturised percutaneous nephrolithotomy for 10–20 mm renal stones: a not so different safety profile BJU Int. (IF 3.7) Pub Date : 2024-11-19 Davide Perri, Umberto Besana, Matteo Maltagliati, Andrea Pacchetti, Tommaso Calcagnile, Antonio Luigi Pastore, Javier Romero‐Otero, Salvatore Micali, Alexander Govorov, Bashkar Somani, Evangelos Liatsikos, Thomas Knoll, Bernardo Rocco, Giorgio Bozzini
ObjectiveTo assess differences in bleeding risk between retrograde intrarenal surgery (RIRS) and minimally invasive miniaturised percutaneous nephrolithotomy (mini‐PCNL) for 10–20 mm renal stones.Patients and methodsA total of 176 patients with a renal stone between 10 and 20 mm were treated. For all patients the Stone Management According to Size‐Hardness (SMASH) score was calculated: Hounsfield units
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Can artificial intelligence evaluate the quality of YouTube videos on erectile dysfunction? BJU Int. (IF 3.7) Pub Date : 2024-11-19 Roei Golan, Aden Swayze, Zachary M. Connelly, Justin Loloi, Kevin Campbell, Aaron C. Lentz, Kara Watts, Alexander Small, Mustufa Babar, Rutul D. Patel, Ranjith Ramasamy, Stacy Loeb
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Fluorescence confocal microscopy for margin assessment in prostatectomy: IP8‐FLUORESCE study protocol BJU Int. (IF 3.7) Pub Date : 2024-11-16 Nikhil Mayor, Alexander Light, Anna Silvanto, Emma Cullen, Peng Yun Ng, Almostafa Badreldin, Bijan Khoubehi, Giles Hellawell, Francesca Fiorentino, Martin J. Connor, Taimur T. Shah, Hashim U. Ahmed, Mathias Winkler
BackgroundRadical prostatectomy (RP) represents the cornerstone of surgical treatment for prostate cancer. Assessing surgical margin status intraoperatively with current techniques remains challenging due to high costs in the context of an already stretched pathology workforce. Fluorescence confocal microscopy (FCM) is a promising technique to detect margins in prostate cancer surgery not bound by
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Oncological microdissection testicular sperm extraction (Onco‐microTESE) outcomes for fertility preservation of patients with testicular cancer with azoospermia or severe oligoasthenoteratozoospermia BJU Int. (IF 3.7) Pub Date : 2024-11-16 Jack B. Fanshawe, Thomas Hughes, Karen Briggs, Raveen Sandher, Yacoub Khalaf, Tet Yap, Julia Kopeika, Majid Shabbir
ObjectiveTo determine the success rate of oncological microdissection testicular sperm extraction (onco‐microTESE) in patients with testicular cancer (TC) with azoospermia and severe oligoasthenoteratozoospermia (OAT; <1 million/mL sperm) and to explore any factors that may predict success.Patients and MethodsCase series of outcomes from all consecutive patients (42 testes in 38 patients) that presented
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‘Case of the Month’ from the University of Verona, Italy—navigating the medical and surgical challenges of urinary bladder paraganglioma: insights from a clinical case BJU Int. (IF 3.7) Pub Date : 2024-11-16 Lorenzo Pierangelo Treccani, Francesco Artoni, Claudio Brancelli, Alessandro Veccia, Mirko D'Onofrio, Isabella Pichiri, Matteo Brunelli, Riccardo Giuseppe Bertolo, Alessandro Antonelli
The Case Report A 44-year-old woman came to us with a history of two paravesical masses, monitored via radiological imaging for 10 years. The patient's medical history revealed multiple episodes of pulmonary embolism after orthopaedic surgery since the age of 22 years. The patient tested negative for any form of coagulopathy. To note, the patient had developed hypertension at a young age, necessitating
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Evaluating the efficacy of physiotherapy in post‐prostatectomy continence and pelvic muscle function BJU Int. (IF 3.7) Pub Date : 2024-11-13 Wei‐Zhen Tang, Wei‐Ze Xu, Tai‐Hang Liu
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A novel approach to integrated prostate cancer diagnostics: insights from MRI, prostate biopsy, and pathology reports in a pilot study BJU Int. (IF 3.7) Pub Date : 2024-11-13 Erik Thimansson, Elin Axén, Fredrik Jäderling, Johan Styrke, Maria Nyberg, Nina Hageman, Johan Ivarsson, Gert Malmberg, Viktoria Gaspar, Magnus Törnblom
In the diagnostic pathway for early detection of prostate cancer, MRI, biopsies, and pathology are included. The shift towards ‘MRI first’ avoids unnecessary biopsies and reduces overdiagnosis [1] but demands high standards for Prostate Imaging-Reporting and Data System (PI-RADS) [2] grading and accuracy in targeted biopsies. Formulating a comprehensive assessment for optimal patient management is
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Response to Tang et al. ‘Evaluating the efficacy of physiotherapy in post‐prostatectomy continence and pelvic muscle function’ BJU Int. (IF 3.7) Pub Date : 2024-11-13 Mifuka Ouchi, Takeya Kitta
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EndoSheath use in flexible cystoscopy: a prospective evaluation of >1000 cases BJU Int. (IF 3.7) Pub Date : 2024-11-13 Lara Ratcliffe, Brian Birch
ObjectivesTo investigate patient tolerability and safety (using urinary tract infection (UTI) as a proxy measure) following EndoSheath‐assisted flexible cystoscopy (eFC). EndoSheaths are single‐use, disposable sheaths used in FC. They reduce cystoscope turnaround times as complicated, time‐consuming and costly sterilisation is no longer necessary. This reduces patient waiting times as cystoscope idle
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Real‐world use of androgen‐deprivation therapy intensification for metastatic hormone‐sensitive prostate cancer: a systematic review BJU Int. (IF 3.7) Pub Date : 2024-11-12 Amit D. Raval, Stephanie Chen, Natasha Littleton, Niculae Constantinovici, Peter J. Goebell
ObjectiveTo conduct a systematic literature review of real‐world data (RWD) studies to summarise treatment patterns among men with metastatic hormone‐sensitive prostate cancer (mHSPC). While androgen‐deprivation therapy (ADT) is a primary treatment strategy for mHSPC, ADT intensification with androgen receptor pathway inhibitors (ARPIs) and/or chemotherapy is recommended by current guidelines and has
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Lower pole stones 1–2 cm: navigating treatment choices BJU Int. (IF 3.7) Pub Date : 2024-11-12 Carlotta Nedbal, Bhaskar K. Somani
Lower-pole renal stones might represent a challenge in endoscopic treatment, especially for intermediate sizes (1–2 cm), that come with no strong indication or contraindication for one technique over the other [1]. The sharp infundibulopelvic angle, together with the infudibulopelvic width and length, often determine treatment choices, along with the available expertise, cost and patient choice. On
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Clinical value of contralateral biopsies in men with unilateral MRI foci undergoing targeted biopsy BJU Int. (IF 3.7) Pub Date : 2024-11-12 Lars Boesen, Nis Nørgaard, Rasmus Bisbjerg, Vibeke Løgager
ObjectivesTo evaluate the additional prostate cancer detection yield and clinical implications of performing contralateral systematic biopsies in men with unilateral suspicious magnetic resonance imaging (MRI) findings undergoing MRI‐guided transperineal (TP) biopsies in an outpatient clinic.Patients and MethodsA prospective study of 655 consecutive men with unilateral MRI suspicious findings undergoing
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Urogeriatrics: a critical perspective for future urologists BJU Int. (IF 3.7) Pub Date : 2024-11-11 William C. Gibcus, Anne Hong, David C. Chen, Henry C.X. Yao, Anthony Ta, Marlon Perera, Joseph J. Ischia, Damien M. Bolton
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The European Association of Urology talent incubator: bridging competencies for holistic urological care BJU Int. (IF 3.7) Pub Date : 2024-11-09 Fabian P. Stangl, Juan Luis Vásquez
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Adjuvant immunotherapy for high‐risk renal cell carcinoma—now or never? BJU Int. (IF 3.7) Pub Date : 2024-11-08 Tivya Kulasegaran, Niara Oliveira, Craig Gedye, Shomik Sengupta
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The first step in shared decision‐making for prostate cancer screening BJU Int. (IF 3.7) Pub Date : 2024-11-07 Takeshi Takahashi
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Response to Takahashi BJU Int. (IF 3.7) Pub Date : 2024-11-07 Zen Yang Ang, Yuke‐Lin Kong, Zarith Nameyrra Md Nesran, Shaun Wen Huey Lee
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The impact of progression-directed therapy on survival in metastatic castration-refractory prostate cancer: MEDCARE phase 3 trial BJU Int. (IF 3.7) Pub Date : 2024-11-06 Kato Rans, Karolien Goffin, Steven Joniau, Gedske Daugaard, Julie den Hartog, Lodewijk Van Wynsberge, Gert De Meerleer
Metastatic castration-refractory prostate cancer (mCRPC) presents a therapeutic challenge despite advancements in treatment. Once mCRPC is attained, patients face limited survival prospects. Next-line systemic treatment (NEST) is the standard of care for progressive mCRPC, encompassing various therapeutic options with associated toxicity and costs. In patients with oligoprogressive mCRPC, data suggest
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A luminal non‐coding RNA‐based genomic classifier confirms favourable outcomes in patients with clinically organ‐confined bladder cancer treated with radical cystectomy BJU Int. (IF 3.7) Pub Date : 2024-11-01 Joep J. de Jong, James A. Proudfoot, Siamak Daneshmand, Robert S. Svatek, Vikram Naryan, Ewan A. Gibb, Elai Davicioni, Shreyas Joshi, Aaron Dahmen, Roger Li, Brant A. Inman, Paras Shah, Iftach Chaplin, Jonathan Wright, Yair Lotan
ObjectiveTo further evaluate a genomic classifier (GC) in a cohort of patients undergoing radical cystectomy (RC), as long non‐coding RNA (lncRNA)‐based genomic profiling has suggested utility in identifying a distinct tumour subgroup corresponding to a favourable prognosis in patients with bladder cancer.Patients and MethodsTranscriptome‐wide expression profiling using Decipher Bladder was performed
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Unravelling the evolution of medical scientific publishing to hold the promise of science for better patient care BJU Int. (IF 3.7) Pub Date : 2024-10-28 Riccardo Bertolo, Riccardo Campi, Nicholas G Zaorsky, Alessandro Antonelli, Sergio Serni, Alessandro Crestani, Gianluca Giannarini
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Mortality rates in radical cystectomy patients with bladder cancer after radiation therapy for prostate cancer BJU Int. (IF 3.7) Pub Date : 2024-10-28 Mario de Angelis, Carolin Siech, Francesco Di Bello, Natali Rodriguez Peñaranda, Jordan A. Goyal, Zhe Tian, Nicola Longo, Felix K.H. Chun, Stefano Puliatti, Fred Saad, Shahrokh F. Shariat, Giorgio Gandaglia, Marco Moschini, Mattia Longoni, Francesco Montorsi, Alberto Briganti, Pierre I. Karakiewicz
ObjectiveTo conduct a population‐based study examining cancer‐specific mortality (CSM) and other‐cause mortality (OCM) differences in patients with radiation‐induced secondary bladder cancer (RT‐BCa) vs those with primary bladder cancer (pBCa) undergoing radical cystectomy (RC).MethodsWithin the Surveillance, Epidemiology, and End Results database (2004–2020), we identified patients with T2–4N0–3M0
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An international multicentre randomised controlled trial of en bloc resection of bladder tumour vs conventional transurethral resection of bladder tumour: first results of the en bloc resection of urothelium carcinoma of the bladder (EBRUC) II trial BJU Int. (IF 3.7) Pub Date : 2024-10-27 Julian Peter Struck, Nadim Moharam, Armin Leitenberger, Jörg Weber, Lukas Lusuardi, David Oswald, Jens J. Rassweiler, Marcel Fiedler, Jakub Horňák, Marek Babjuk, Salvatore Micali, Carlo Zaraca, Thomas Spreu, Frank Friedersdorff, Hendrik Borgmann, Axel S. Merseburger, Mario W. Kramer
ObjectivesTo determine the safety and oncological advantages of en bloc resection of bladder tumour (ERBT) vs conventional transurethral resection of bladder tumour (cTURBT) in terms of resection quality, staging quality, and safety.Patients and MethodsWe conducted a single‐blinded randomised controlled trial at seven European hospitals with the following inclusion criteria: first diagnosis of non‐muscle‐invasive
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Clinical determination of the natural distensibility of the human ureter: initial study BJU Int. (IF 3.7) Pub Date : 2024-10-26 Sohrab N. Ali, Amanda McCormac, Andrei D. Cumpanas, Jaime Altamirano‐Villarroel, Paul Piedras, Minh‐Chau Vu, Andrew S. Afyouni, Zachary E. Tano, Kathryn Osann, Michael Klopfer, Pengbo Jiang, Roshan M. Patel, Jaime Landman, Ralph V. Clayman
ObjectivesTo define the natural distensibility of the human ureter and evaluate the impact of other possibly favourable factors on ureteric distensibility.Patients and MethodsA total of 101 patients undergoing ureteroscopic stone removal or percutaneous nephrolithotomy underwent ureteric sizing using sequential passage of 37‐cm urethral dilators in 2‐F increments while attached to a unique force sensor
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Insurance remains a major source of disparity for patients with testicular cancer: call for advocacy BJU Int. (IF 3.7) Pub Date : 2024-10-26 Savannah Starr, Jj Zhang, Lin Lin, Jolie Shen, Giovanni Gamalong, Mark S. Litwin, Alexandra Drakaki, Karim Chamie
ObjectiveTo evaluate the effects of socioeconomic factors, including insurance status, on treatment and survival for patients with testicular cancer.Patients and MethodsWe extracted a retrospective cohort from the National Cancer Database that included patients diagnosed with testicular cancer 2004–2020. Competing‐risks and Cox regression multivariate models including demographic, pathological, and