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ObjectiveTo assess differences in bleeding risk between retrograde intrarenal surgery (RIRS) and minimally invasive miniaturised percutaneous nephrolithotomy (mini‐PCNL) for 10–20 mm renal stones.Patients and methodsA total of 176 patients with a renal stone between 10 and 20 mm were treated. For all patients the Stone Management According to Size‐Hardness (SMASH) score was calculated: Hounsfield units

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BackgroundRadical prostatectomy (RP) represents the cornerstone of surgical treatment for prostate cancer. Assessing surgical margin status intraoperatively with current techniques remains challenging due to high costs in the context of an already stretched pathology workforce. Fluorescence confocal microscopy (FCM) is a promising technique to detect margins in prostate cancer surgery not bound by

ObjectiveTo determine the success rate of oncological microdissection testicular sperm extraction (onco‐microTESE) in patients with testicular cancer (TC) with azoospermia and severe oligoasthenoteratozoospermia (OAT; <1 million/mL sperm) and to explore any factors that may predict success.Patients and MethodsCase series of outcomes from all consecutive patients (42 testes in 38 patients) that presented

The Case Report A 44-year-old woman came to us with a history of two paravesical masses, monitored via radiological imaging for 10 years. The patient's medical history revealed multiple episodes of pulmonary embolism after orthopaedic surgery since the age of 22 years. The patient tested negative for any form of coagulopathy. To note, the patient had developed hypertension at a young age, necessitating

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In the diagnostic pathway for early detection of prostate cancer, MRI, biopsies, and pathology are included. The shift towards ‘MRI first’ avoids unnecessary biopsies and reduces overdiagnosis [1] but demands high standards for Prostate Imaging-Reporting and Data System (PI-RADS) [2] grading and accuracy in targeted biopsies. Formulating a comprehensive assessment for optimal patient management is

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ObjectivesTo investigate patient tolerability and safety (using urinary tract infection (UTI) as a proxy measure) following EndoSheath‐assisted flexible cystoscopy (eFC). EndoSheaths are single‐use, disposable sheaths used in FC. They reduce cystoscope turnaround times as complicated, time‐consuming and costly sterilisation is no longer necessary. This reduces patient waiting times as cystoscope idle

ObjectiveTo conduct a systematic literature review of real‐world data (RWD) studies to summarise treatment patterns among men with metastatic hormone‐sensitive prostate cancer (mHSPC). While androgen‐deprivation therapy (ADT) is a primary treatment strategy for mHSPC, ADT intensification with androgen receptor pathway inhibitors (ARPIs) and/or chemotherapy is recommended by current guidelines and has

Lower-pole renal stones might represent a challenge in endoscopic treatment, especially for intermediate sizes (1–2 cm), that come with no strong indication or contraindication for one technique over the other [1]. The sharp infundibulopelvic angle, together with the infudibulopelvic width and length, often determine treatment choices, along with the available expertise, cost and patient choice. On

ObjectivesTo evaluate the additional prostate cancer detection yield and clinical implications of performing contralateral systematic biopsies in men with unilateral suspicious magnetic resonance imaging (MRI) findings undergoing MRI‐guided transperineal (TP) biopsies in an outpatient clinic.Patients and MethodsA prospective study of 655 consecutive men with unilateral MRI suspicious findings undergoing

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BackgroundMetastatic castration‐refractory prostate cancer (mCRPC) presents a therapeutic challenge despite advancements in treatment. Once mCRPC is attained, patients face limited survival prospects. Next‐line systemic treatment (NEST) is the standard of care for progressive mCRPC, encompassing various therapeutic options with associated toxicity and costs. In patients with oligoprogressive mCRPC

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ObjectiveTo further evaluate a genomic classifier (GC) in a cohort of patients undergoing radical cystectomy (RC), as long non‐coding RNA (lncRNA)‐based genomic profiling has suggested utility in identifying a distinct tumour subgroup corresponding to a favourable prognosis in patients with bladder cancer.Patients and MethodsTranscriptome‐wide expression profiling using Decipher Bladder was performed

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ObjectiveTo conduct a population‐based study examining cancer‐specific mortality (CSM) and other‐cause mortality (OCM) differences in patients with radiation‐induced secondary bladder cancer (RT‐BCa) vs those with primary bladder cancer (pBCa) undergoing radical cystectomy (RC).MethodsWithin the Surveillance, Epidemiology, and End Results database (2004–2020), we identified patients with T2–4N0–3M0

ObjectivesTo determine the safety and oncological advantages of en bloc resection of bladder tumour (ERBT) vs conventional transurethral resection of bladder tumour (cTURBT) in terms of resection quality, staging quality, and safety.Patients and MethodsWe conducted a single‐blinded randomised controlled trial at seven European hospitals with the following inclusion criteria: first diagnosis of non‐muscle‐invasive

ObjectivesTo define the natural distensibility of the human ureter and evaluate the impact of other possibly favourable factors on ureteric distensibility.Patients and MethodsA total of 101 patients undergoing ureteroscopic stone removal or percutaneous nephrolithotomy underwent ureteric sizing using sequential passage of 37‐cm urethral dilators in 2‐F increments while attached to a unique force sensor

ObjectiveTo evaluate the effects of socioeconomic factors, including insurance status, on treatment and survival for patients with testicular cancer.Patients and MethodsWe extracted a retrospective cohort from the National Cancer Database that included patients diagnosed with testicular cancer 2004–2020. Competing‐risks and Cox regression multivariate models including demographic, pathological, and

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ObjectiveTo conduct a systematic review of the current literature to determine the current role of primary retroperitoneal lymph node dissection (RPLND) in stage II testicular seminoma and its associated oncological, functional and peri‐operative outcomes.Materials and MethodsA comprehensive literature search was conducted in Medline, Embase, and Scopus for publications from inception until November

ObjectiveTo evaluate the relationship between renal pelvis pressure and infection after ureteroscopy, using a live swine model.Materials and MethodsIn anaesthetised pigs, a 1‐h ureteroscopy was performed using a pressure‐sensing guidewire, with renal pelvis pressure maintained at either 37 mmHg or 75 mmHg for the entire procedure and infusion with saline alone or with a standardised concentration of

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ObjectiveTo compare the safety and efficacy of flexible ureteroscopy (f‐URS) and ambulatory tubeless mini‐percutaneous nephrolithotomy (mini‐PCNL) in the treatment of 1–2 cm lower calyceal renal stones.Patients and MethodsPatients who underwent f‐URS and mini‐PCNL for the treatment of 1–2 cm lower calyceal renal stones between October 2020 and November 2023 were evaluated in a randomised controlled

ObjectiveTo determine the diagnostic test accuracy of multiparametric magnetic resonance imaging (mpMRI) in detecting seminal vesicle invasion (SVI).MethodsThe Medical Literature Analysis and Retrieval System Online (MEDLINE), PubMed, the Excerpta Medica dataBASE (EMBASE) and Cochrane databases were search up to May 2023. We included studies that investigated the accuracy of mpMRI in detecting SVI

ObjectivesTo assess the comparative effectiveness of robot‐assisted radical cystectomy (RARC) with intracorporeal urinary diversion (ICUD) vs open radical cystectomy (ORC) for bladder cancer (BC).Patients and MethodsWe conducted a real‐life monocentric study including all consecutive patients who underwent RARC with ICUD or ORC for BC at our institution from 2014 to 2023. Uni‐ and multivariable logistic

ObjectivesTo characterise the long‐term success rate of ventral onlay buccal mucosa graft urethroplasty (vBMG) in the management of bulbar urethral stricture disease (USD), assess patient‐reported postoperative satisfaction and decision regret, and delineate clinical factors impacting patient‐reported metrics.Subjects and MethodsPatients with prior vBMG for bulbar USD, performed at Cleveland Clinic

It has been reported that there is a limited amount of training on research/methodological skills during urological residency in Europe [1]. The Young Academic Urologists (YAU) of the European Association of Urology (EAU) aims to promote and perform high-quality research to provide high-quality evidence for the best urological care, as well as to promote educational programmes to boost European training

ObjectiveTo characterise the effect of solitary and serial manual bolus irrigations on intrarenal pressures (IRPs) and observe the clinical consequences.Patients and MethodsA pressure guidewire was used for IRP measurement during routine flexible ureterorenoscopy for management of renal stone disease, including manual bolus irrigation when required to maintain vision. The fluid bolus was either as

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The Young Academic Urologists (YAU) is a group of young clinician-scientists (aged <40 years) within the European Association of Urology (EAU) focusing on the development of clinical, educational, and research projects. In particular, due to strategic partnerships with the Guidelines Office, the Sections Office and the European School of Urology (ESU), the goals of YAU are to promote both high-quality

ObjectiveTo assess recurrence‐free survival (RFS) in patients with undetectable tumour‐informed circulating tumour DNA (ctDNA) before radical cystectomy (RC) and evaluate if those who converted from detectable to undetectable ctDNA status after RC have similar RFS outcomes as those with persistently undetectable ctDNA status.Patients and MethodsPatients who underwent RC had prospectively and longitudinally

ObjectiveTo evaluate the safety and effectiveness of bladder irrigation (BI) with tap water to reduce antibiotic use for the treatment of urinary tract infections (UTIs) in patients with recurrent UTI symptoms and to assess the treatment satisfaction of BI.Patients and MethodsThis prospective, observational study included patients with an indwelling catheter or performing clean intermittent catheterisation

ObjectiveTo review and compare the efficacy of different delivery modes of decision aids (DAs), including computer‐based, print‐based, multimedia‐based, video‐based, and website‐based on decision‐making outcomes for prostate cancer screening compared to usual care (UC) and among the delivery modes.MethodsPubMed, the Excerpta Medica dataBASE (EMBASE), Cumulative Index to Nursing and Allied Health Literature

ObjectiveTo investigate the outcomes of ureteroscopy and lasertripsy in lower pole renal stones <2 cm when treated in situ compared to displacement to the upper pole.Patients and MethodsUsing the Medical Literature Analysis and Retrieval System Online (MEDLINE)/PubMed, the Excerpta Medica dataBASE (EMBASE), Cumulative Index to Nursing and Allied Health Literature (CINAHL), the Cochrane Library, and

BackgroundA second transurethral resection of bladder tumour (Re‐TURBT) is recommended by European Association of Urology (EAU) Guidelines on non‐muscle‐invasive bladder cancers (NMIBCs) due to the risk of understaging and/or persistent disease following the primary resection. However, in many cases this may be unnecessary, potentially harmful, and significantly expensive constituting overtreatment

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ObjectiveTo analyse the management and outcomes of individuals diagnosed with prostate cancer either before or after organ transplantation, as the impact of organ transplantation and associated immunosuppression on the incidence, progression, and mortality of prostate cancer remains an area of substantial clinical interest and uncertainty.Patients and MethodsWe conducted a retrospective analysis of

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ObjectiveTo evaluate the safety, efficacy, tolerability, and cost‐effectiveness of bedside or office‐based ureteric stent insertion.MethodsFollowing Preferred Reporting Items for Systematic Reviews and Meta‐Analyses‐Protocols (PRISMA‐P) and A MeaSurement Tool to Assess systematic Reviews (AMSTAR) 2 guidelines, we searched PubMed/the Medical Literature Analysis and Retrieval System Online (MEDLINE)

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