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Reversal of cerebral ischaemia and hypoxia and of sickness behaviour by megadose sodium ascorbate in ovine Gram-negative sepsis Br. J. Anaesth. (IF 9.1) Pub Date : 2024-07-02 Clive N. May, Connie P. Ow, Ruslan V. Pustovit, Darius J. Lane, Alemayehu H. Jufar, Anton Trask-Marino, Rachel M. Peiris, Adam Gunn, Lindsea C. Booth, Mark P. Plummer, Rinaldo Bellomo, Yugeesh R. Lankadeva
The mechanisms by which megadose sodium ascorbate improves clinical status in experimental sepsis is unclear. We determined its effects on cerebral perfusion, oxygenation, and temperature, and plasma levels of inflammatory biomarkers, nitrates, nitrites, and ascorbate in ovine Gram-negative sepsis. Sepsis was induced by i.v. infusion of live for 31 h in unanaesthetised Merino ewes instrumented with
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Dexmedetomidine in paediatric anaesthesia: a call for action? Br. J. Anaesth. (IF 9.1) Pub Date : 2024-06-25 Laszlo Vutskits
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Association of anaesthesia provider sex with perioperative complications: a two-centre retrospective cohort study Br. J. Anaesth. (IF 9.1) Pub Date : 2024-06-25 Dario von Wedel, Simone Redaelli, Luca J. Wachtendorf, Elena Ahrens, Maíra I. Rudolph, Denys Shay, Laetitia S. Chiarella, Aiman Suleiman, Ricardo Munoz-Acuna, Sarah Ashrafian, Eva-Lotte Seibold, Stephen Woloszynek, Guanqing Chen, Daniel Talmor, Valerie Banner-Goodspeed, Matthias Eikermann, Nancy E. Oriol, Maximilian S. Schaefer
Previous studies suggested that surgeon sex is associated with differential patient outcomes. Whether this also applies to anaesthesia providers is unclear. We hypothesised that female sex of the primary anaesthesia provider is associated with lower risk of perioperative complications. The first case for all adult patients undergoing anaesthesia care between 2008 and 2022 at two academic healthcare
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Remimazolam versus propofol for sedation in gastrointestinal endoscopic procedures: a systematic review and meta-analysis. Comment on Br J Anaesth 2024; 132: 1219–29 Br. J. Anaesth. (IF 9.1) Pub Date : 2024-06-21 Tianqi Shen, Xincan An, Xingxing Yin, Jing Wen
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Professionalisation and specialisation in the practice of anaesthesia in the UK Br. J. Anaesth. (IF 9.1) Pub Date : 2024-06-21 Alistair G. McKenzie, Henry Connor
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Charting the course for improved outcomes in chronic critical illness: therapeutic strategies for persistent inflammation, immunosuppression, and catabolism syndrome (PICS) Br. J. Anaesth. (IF 9.1) Pub Date : 2024-06-19 Valerie E. Polcz, Evan L. Barrios, Shawn D. Larson, Philip A. Efron, Jaimar C. Rincon
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The debate rages on: physician-assisted suicide in an ethical light. Response to Br J Anaesth 2024; 132:1179–83 Br. J. Anaesth. (IF 9.1) Pub Date : 2024-06-18 John Shenouda, Michael Blaber, Robert George, James Haslam
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Preoperative pain sensitivity and its correlation with postoperative acute and chronic pain: a systematic review and meta-analysis Br. J. Anaesth. (IF 9.1) Pub Date : 2024-06-15 Fan Wu, Jiehui Liu, Liang Zheng, Changqi Chen, Diksha Basnet, Jingya Zhang, Chaonan Shen, Xuanran Feng, Yiyan Sun, Xue Du, Jialin C. Zheng, Jianhui Liu
Preoperative pain sensitivity (PPS) can be associated with postsurgical pain. However, estimates of this association are scarce. Confirming this correlation is essential to identifying patients at high risk for severe postoperative pain and for developing analgesic strategy. This systematic review and meta-analysis summarises PPS and assessed its correlation with postoperative pain. PubMed, Scopus
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Retraction notice to “Discharge of postoperative patients with an opioid prescription is associated with increased persistent opioid use, healthcare expenditures and mortality: a retrospective cohort study” [Br J Anaesth 131 (2023) 586–597] Br. J. Anaesth. (IF 9.1) Pub Date : 2024-06-14 Xiaodong Liu, Carlos K.H. Wong, Tingting Wu, Eric H.M. Tang, Ivan C.H. Au, Lanlan Li, Chi W. Cheung, Brian H.-H. Lang
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Opioid-free versus opioid-sparing anaesthesia in ambulatory total hip arthroplasty. Comment on Br J Anaesth 2024; 132: 352–8 Br. J. Anaesth. (IF 9.1) Pub Date : 2024-06-13 Andrew Maxwell
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Epidural analgesia in labour: separating fact from fiction for autism and neurodevelopment Br. J. Anaesth. (IF 9.1) Pub Date : 2024-06-13 Rachel J. Kearns, Scott M. Nelson, Steffen Rex
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Individualising goal-directed haemodynamic therapy: future iterations will require novel trial designs Br. J. Anaesth. (IF 9.1) Pub Date : 2024-06-13 Mark R. Edwards
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Critical airway-related incidents and near misses in anaesthesia: a qualitative study of a critical incident reporting system Br. J. Anaesth. (IF 9.1) Pub Date : 2024-06-12 Tina H. Pedersen, Sabine Nabecker, Robert Greif, Lorenz Theiler, Maren Kleine-Brueggeney
Many serious adverse events in anaesthesia are retrospectively rated as preventable. Anonymous reporting of near misses to a critical incident reporting system (CIRS) can identify structural weaknesses and improve quality, but incidents are often underreported. This prospective qualitative study aimed to identify conceptions of a CIRS and reasons for underreporting at a single Swiss centre. Anaesthesia
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Effects of general anaesthesia in early childhood on local and global visual processing: a post hoc analysis of the APEX cohort study Br. J. Anaesth. (IF 9.1) Pub Date : 2024-06-10 Jean-Philippe Salaün, Grégoire Borst, Arnaud Cachia, François Orliac, Denis Vivien, Nicolas Poirel
Preclinical studies suggest that early exposure to anaesthesia alters the visual system in mice and non-human primates. We investigated whether exposure to general anaesthesia leads to visual attention processing changes in children, which could potentially impact essential life skills, including learning. This was a analysis of data from the APprentissages EXécutifs et cerveau chez les enfants d’âge
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Genome-wide association studies with experimental validation identify a protective role for B lymphocytes against chronic post-surgical pain Br. J. Anaesth. (IF 9.1) Pub Date : 2024-06-10 Marc Parisien, Roel R.I. van Reij, Samar Khoury, Eda Koseli, Mohamad Karaky, Jaqueline R. Silva, Golnar Taheri, Nynke J. van den Hoogen, Garrie Peng, Massimo Allegri, Manuela De Gregori, Jacques E. Chelly, Barbara A. Rakel, Eske K. Aasvang, Henrik Kehlet, Wolfgang F.F.A. Buhre, Camron D. Bryant, M. Imad Damaj, Irah L. King, Nader Ghasemlou, Jeffrey S. Mogil, Elbert A.J. Joosten, Luda Diatchenko
Chronic post-surgical pain (CPSP) significantly impacts patients' recovery and quality of life. Although environmental risk factors are well-established, genetic risk remains less understood. A meta-analysis of genome-wide association studies followed by partitioned heritability was performed on 1350 individuals across five surgery types: hysterectomy, mastectomy, abdominal, hernia, and knee. In subsequent
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Impact of spinal versus general anaesthesia on perioperative obstructive sleep apnoea severity in patients undergoing hip arthroplasty: a post hoc analysis of two randomised controlled trials Br. J. Anaesth. (IF 9.1) Pub Date : 2024-06-10 Eric Albrecht, Julien Wegrzyn, Jean-Benoit Rossel, Virginie Bayon, Raphaël Heinzer
Recommendations suggest favouring regional over general anaesthesia to reduce impact on postoperative sleep apnoea severity, but there is currently no evidence to support this. We compared the impact of general spinal anaesthesia on postoperative sleep apnoea severity and assessed the evolution of sleep apnoea severity up to the third postoperative night. This analysis used pooled data from two previous
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Prediction of sustained opioid use in children and adolescents using machine learning Br. J. Anaesth. (IF 9.1) Pub Date : 2024-06-10 Dor Atias, Aviv Tuttnauer, Noam Shomron, Uri Obolski
Opioid misuse in the paediatric population is understudied. This study aimed to develop a machine learning classifier to differentiate between occasional and sustained opioid users among children and adolescents in outpatient settings. Data for 29,335 patients under 19 yr with recorded opioid purchases were collected from medical records. Machine learning methods were applied to predict sustained opioid
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Effect of volatile versus propofol anaesthesia on major complications and mortality after cardiac surgery: a multicentre randomised trial Br. J. Anaesth. (IF 9.1) Pub Date : 2024-06-05 Xiao-Qian Deng, Hong Yu, Wei-Jian Wang, Qiao-Lin Wu, Hua Wei, Jing-Song Deng, Zhi-Jian Li, Jin-Zheng Wu, Jian-Jun Yang, Xiang-Ming Zheng, Jin-Ju Wei, Shuai-Shuai Fan, Xiao-Hua Zou, Jing Shi, Fang-Xiang Zhang, Da-Qing Wu, Dang-Pei Kou, Tao Wang, E Wang, Zhi Ye, Xing Zheng, Gang Chen, Wen-Qi Huang, Yu Chen, Xin Wei, Xiao-Qing Chai, Wei-Qin Huang, Ling Wang, Kai Li, Liang Li, Ye Zhang, Rui Li, Jia-Li
The comparative effectiveness of volatile anaesthesia and total intravenous anaesthesia (TIVA) in terms of patient outcomes after cardiac surgery remains a topic of debate. Multicentre randomised trial in 16 tertiary hospitals in China. Adult patients undergoing elective cardiac surgery were randomised in a 1:1 ratio to receive volatile anaesthesia (sevoflurane or desflurane) or propofol-based TIVA
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Patient-reported outcomes: validation of the French Quality of Recovery-15 score in cardiac surgery Br. J. Anaesth. (IF 9.1) Pub Date : 2024-06-04 Grégoire Le Gac, Alexandre Mansour, Martin Labory, Erwan Flecher, Céline Chabanne, Claude Ecoffey, Hélène Beloeil, Nicolas Nesseler
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Risk of perioperative discontinuation of SGLT2 inhibitors Br. J. Anaesth. (IF 9.1) Pub Date : 2024-06-04 Maartina J.P. Oosterom-Eijmael, Jeroen Hermanides, Daniel H. van Raalte, Abraham H. Hulst
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GLP-1 receptor agonist tachyphylaxis and perioperative recommendations Br. J. Anaesth. (IF 9.1) Pub Date : 2024-06-04 Fei Wu, Seth A. Klapman, Lucinda L. Everett, Braden Kuo, Ion A. Hobai
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PeriOperative Quality Initiative (POQI) international consensus statement on perioperative arterial pressure management Br. J. Anaesth. (IF 9.1) Pub Date : 2024-06-04 Bernd Saugel, Nick Fletcher, Tong J. Gan, Michael P.W. Grocott, Paul S. Myles, Daniel I. Sessler, PeriOperative Quality Initiative XI (POQI XI) Workgroup Members
Arterial pressure monitoring and management are mainstays of haemodynamic therapy in patients having surgery. This article presents updated consensus statements and recommendations on perioperative arterial pressure management developed during the 11th POQI PeriOperative Quality Initiative (POQI) consensus conference held in London, UK, on June 4–6, 2023, which included a diverse group of international
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Co-prescription of naloxone in patients prescribed opioids after hospital stays in the USA Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-31 Alex Illescas, Jiabin Liu, Haoyan Zhong, Lisa Reisinger, Crispiana Cozowicz, Jashvant Poeran, Stavros G. Memtsoudis
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The educational impact of technology-enhanced learning in regional anaesthesia: a scoping review Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-31 Mairead Savage, Andrew Spence, Lloyd Turbitt
Effective training in regional anaesthesia (RA) is paramount to ensuring widespread competence. Technology-based learning has assisted other specialties in achieving more rapid procedural skill acquisition. If applicable to RA, technology-enhanced training has the potential to provide an effective learning experience and to overcome barriers to RA training. We review the current evidence base for use
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Weaning from mechanical ventilation in the operating room: a systematic review Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-29 Megan Abbott, Sergio M. Pereira, Noah Sanders, Martin Girard, Ashwin Sankar, Michael C. Sklar
Postoperative pulmonary complications (PPCs) are associated with postoperative mortality and prolonged hospital stay. Although intraoperative mechanical ventilation (MV) is a risk factor for PPCs, strategies addressing weaning from MV are understudied. In this systematic review, we evaluated weaning strategies and their effects on postoperative pulmonary outcomes. Our protocol was registered on PROSPERO
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Relationship between mental effort and workload during routine anaesthesia Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-28 Craig S. Webster, Leanne Huang, Ties Coomber, Robert O.S. Grieve, Cornelis J. Kruger, Marcus A. Henning
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Impact of spinal or epidural anaesthesia on perioperative outcomes in adult noncardiac surgery: a narrative review of recent evidence Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-28 David W. Hewson, Tiffany R. Tedore, Jonathan G. Hardman
Spinal and epidural anaesthesia and analgesia are important anaesthetic techniques, familiar to all anaesthetists and applied to patients undergoing a range of surgical procedures. Although the immediate effects of a well-conducted neuraxial technique on nociceptive and sympathetic pathways are readily observable in clinical practice, the impact of such techniques on patient-centred perioperative outcomes
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Cardiac index-guided therapy to maintain optimised postinduction cardiac index in high-risk patients having major open abdominal surgery: the multicentre randomised iPEGASUS trial Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-26 Sandra Funcke, Götz Schmidt, Alina Bergholz, Pilar Argente Navarro, Gonzalo Azparren Cabezón, Silvia Barbero-Espinosa, Oscar Diaz-Cambronero, Fabian Edinger, Nuria García-Gregorio, Marit Habicher, Gerd Klinkmann, Christian Koch, Alina Kröker, Thomas Mencke, Victoria Moral García, Amelie Zitzmann, Susanne Lezius, Amra Pepić, Daniel I. Sessler, Michael Sander, Sebastian A. Haas, Daniel A. Reuter, Bernd
It is unclear whether optimising intraoperative cardiac index can reduce postoperative complications. We tested the hypothesis that maintaining optimised postinduction cardiac index during and for the first 8 h after surgery reduces the incidence of a composite outcome of complications within 28 days after surgery compared with routine care in high-risk patients having elective major open abdominal
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Maintenance of beta-blockers and cardiac surgery-related outcomes: a prospective propensity-matched multicentre analysis Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-23 Pierre-Grégoire Guinot, Marc-Olivier Fischer, Maxime Nguyen, Vivien Berthoud, Jean B. Decros, Guillaume Besch, Belaid Bouhemad
We investigated the effects of maintaining beta-blockers on the day of surgery on the incidence of atrial fibrillation and postoperative acute kidney injury (AKI) in patients undergoing cardiac surgery. We conducted a multicentre prospective observational study with propensity matching on patients treated with beta-blockers. We collected their baseline patient characteristics, comorbidities, and operative
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Intravenous versus perineural dexamethasone to prolong analgesia after interscalene brachial plexus block: a systematic review with meta-analysis and trial sequential analysis Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-23 Eric Albrecht, Yves Renard, Neel Desai
The efficacy of perineural intravenous dexamethasone as a local anaesthetic adjunct to increase duration of analgesia could be particular to specific peripheral nerve blocks because of differences in systemic absorption depending on the injection site. Given this uncertainty, we performed a systematic review with meta-analysis and trial sequential analysis comparing dexamethasone administered perineurally
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Prevalence and characteristics of preoperative patients with depression Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-22 Tuuli M. Hietamies, Ashleigh E. Smith, Theresa R. Lii, Evan Muzzall, Josephine Flohr, Robin L. Okada, Zachary G. Andriella, Cynthia A. Nyongesa, Lisa J. Cianfichi, Laura M. Hack, Boris D. Heifets
Within the perioperative period, depression-related diagnoses are associated with postoperative complications. We developed a perioperative depression screening programme to assess disease prevalence and feasibility for intervention. Adult patients in multiple surgical departments at a single academic centre were screened for depression via the electronic health record patient portal or preoperative
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Hypotension after general anaesthesia induction using remimazolam or propofol in geriatric patients undergoing sevoflurane anaesthesia with remifentanil: a single-centre, double-blind, randomised controlled trial Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-22 Ryuki Takaki, Masashi Yokose, Takahiro Mihara, Yusuke Saigusa, Hiroyuki Tanaka, Natsuhiro Yamamoto, Kenichi Masui, Takahisa Goto
The occurrence of hypotension after induction of general anaesthesia is common in geriatric patients, and should be prevented to minimise perioperative complications. Compared with propofol, remimazolam potentially has a lower incidence of hypotension. This study aimed to compare the incidence of hypotension after general anaesthesia induction with remimazolam or propofol in geriatric patients. This
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Identifying the blue patient: preoperative screening for depression Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-22 Bradley A. Fritz, Katherine J. Holzer
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Ultrasound-guided suprainguinal fascia iliaca compartment block and early postoperative analgesia after total hip arthroplasty: a randomised controlled trial Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-18 Ben Safa, Hawn Trinh, Andrew Lansdown, Paul G. McHardy, Jeffrey Gollish, Alex Kiss, Lilia Kaustov, Stephen Choi
Hip replacement surgery can be painful; postoperative analgesia is crucial for comfort and to facilitate recovery. Regional anaesthesia can reduce pain and postoperative opioid requirements. The role of ultrasound-guided suprainguinal fascia iliaca block for analgesia after elective total hip arthroplasty is not well defined. This randomised trial evaluated its analgesic efficacy. Consenting participants
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Reversing the triad of anaesthesia in a cannot intubate, cannot oxygenate emergency Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-16 Moqiang Zhang, Huizi Liu, Xue Han, Jinfeng Guo, Yunfen Ge
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The effect of diabetes mellitus on perioperative outcomes after colorectal resection: a national cohort study Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-16 Savannah Gysling, Christopher A. Lewis-Lloyd, Dileep N. Lobo, Colin J. Crooks, David J. Humes
Diabetes mellitus is a significant modulator of postoperative outcomes and is an important risk factor in the patient selection process. We aimed to investigate the effect of diabetes mellitus and use of insulin on outcomes after colorectal resection using a national cohort. Adults with a recorded colorectal resection in England between 2010 and 2020 were identified from Hospital Episode Statistics
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A new pharmacological approach for tracheal intubation? Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-16 J. Robert Sneyd
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Clinical practice, research, and collaboration with industry: impact of the discontinuation of a critical device Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-14 Dietmar Fries, Johannes Gratz, Lars Asmis, Philipp Groene, Lars Heubner, Felix Schmitt, Herbert Schöchl
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A simple system change to reduce delays in emergency calls for assistance during anaesthesia in the operating theatre Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-14 Craig S. Webster
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Use of electrical stimulation to confirm the erector spinae plane Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-13 Chia Yuan Lee, Nathan Yii, Sophie Turner, Justin Swierczek, Leigh White
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The BJA Editorial Fellowship 2024: a barometer for the state of academic anaesthesiology, perioperative, pain, and critical care medicine Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-13 Emily A. Vail, Gareth L. Ackland
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Dexamethasone and chronic postsurgical pain: the pendulum meets reductionistic thinking Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-13 D. Norman Buckley, W. Scott Beattie
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Development and validation of the Ex-Care BR model: a multicentre initiative for identifying Brazilian surgical patients at risk of 30-day in-hospital mortality Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-10 Sávio C. Passos, Stela M. de Jezus Castro, Adriene Stahlschmidt, Paulo C. da Silva Neto, Paulo J. Irigon Pereira, Plínio da Cunha Leal, Maristela B. Lopes, Luiz F. dos Reis Falcão, Vera L.F. de Azevedo, Eric B. Lineburger, Florentino F. Mendes, Ramon M. Vilela, Liana M.T. de Araújo Azi, Fabrício D. Antunes, Leandro G. Braz, Luciana C. Stefani
Surgical risk stratification is crucial for enhancing perioperative assistance and allocating resources efficiently. However, existing models may not capture the complexity of surgical care in Brazil. Using data from various healthcare settings nationwide, we developed a new risk model for 30-day in-hospital mortality (the Ex-Care BR model). A retrospective cohort study was conducted in 10 hospitals
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Potential for heart rate deceleration capacity in assessing perioperative autonomic function and predicting adverse cardiovascular events Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-09 Xinyi Sun, Lin Xu, Jianjun Li, Wenxi Tang, Penghui Wei
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Association of ketamine use during procedural sedation with oxygen desaturation and healthcare utilisation: a multicentre retrospective hospital registry study. Response to Br J Anaesth 2024; 133: 228–229 Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-09 Karuna Wongtangman, Matthias Eikermann
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Landiolol for perioperative atrial tachyarrhythmias in cardiac and thoracic surgery patients: a systematic review and meta-analysis Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-09 Krzysztof Kowalik, Max Silverman, Alireza Oraii, David Conen, Emilie P. Belley-Côté, Jeff S. Healey, Kevin J. Um, Toru Inami, Patrick M. Wanner, Michael K. Wang, Arjun Pandey, Aadithya Udayashankar, Richard P. Whitlock, P.J. Devereaux, William F. McIntyre
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Reducing the time to activation of the emergency call system in operating theatres: effect of installing vertical red line indicators Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-09 Stuart D. Marshall, Cameron Rush, Lucy Elliott, Harry Wadman, Jane Dang, Ashley St John, Fiona E. Kelly
The 7th National Audit Project of the Royal College of Anaesthetists (NAP7) recommended that an emergency call system be immediately accessible in all anaesthesia locations. It is essential that all theatre team members can rapidly call for help to reduce the risk of patient harm. However, the ability of staff to activate this system in a timely manner can be affected by cluttered or unfamiliar environments
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Clinical use and safety of volatile anaesthetic sedation in mechanically ventilated adult patients: a retrospective single-centre cohort study Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-07 Christopher Remmington, Luigi Camporota, Christopher Meddings, Fraser Hanks, Daniel Taylor, Angelo Sousa, Barnaby Sanderson, Guy Glover
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Behavioural and neuropsychological outcomes in children exposed in utero to maternal labour epidural analgesia Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-03 Oliver G. Isik, Shaqif Junaid, Ling Guo, Deven Lackraj, Ruth Landau, Caleb H. Miles, Craig Pennell, Britta S. von Ungern Sternberg, Andrew J.O. Whitehouse, Guohua Li, Caleb Ing
Recent studies report conflicting results regarding the relationship between labour epidural analgesia (LEA) in mothers and neurodevelopmental disorders in their offspring. We evaluated behavioural and neuropsychological test scores in children of mothers who used LEA. Children enrolled in the Raine Study from Western Australia and delivered vaginally from a singleton pregnancy between 1989 and 1992
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The debate rages on: physician-assisted suicide in an ethical light. Response to Br J Anaesth 2024; 132: 1179–83 Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-03 David G. Bogod
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Mortality following noncardiac surgery assessed by the Saint Louis University Score (SLUScore) for hypotension: a retrospective observational cohort study Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-03 Cristina Barboi, Wolf H. Stapelfeldt
The Saint Louis University Score (SLUScore) was developed to quantify intraoperative blood pressure trajectories and their associated risk for adverse outcomes. This study examines the prevalence and severity of intraoperative hypotension described by the SLUScore and its relationship with 30-day mortality in surgical subtypes. This retrospective analysis of perioperative data included surgical cases
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Research priorities in regional anaesthesia: where should we focus? Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-02 Stuart A. Grant, Sandy Kopp, Eric Albrecht
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Association of ketamine use during procedural sedation with oxygen desaturation and healthcare utilisation: a multicentre retrospective hospital registry study. Comment on Br J Anaesth 2023; 132: 779–88 Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-02 Kentaro Fukano, Yoshinori Matsuoka, Tatsuya Norii
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Intraoperative hypotension and postoperative outcomes: just the tip of the iceberg. Response to Br J Anaesth 2024; 132: 804–5 Br. J. Anaesth. (IF 9.1) Pub Date : 2024-05-02 Filippo D'Amico, Stefano Turi, Giovanni Landoni
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Inpatient dronabinol utilisation: an institutional retrospective study to determine prevalence and indications for clinical application Br. J. Anaesth. (IF 9.1) Pub Date : 2024-04-30 William Chan, Faye Rim, Spencer Liu, Kethy Jules-Elysee, Jiabin Liu, Stavros Memtsoudis, Alexandra Sideris
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Improved outcome with individualised antifibrinolytic therapy: what is the evidence? Br. J. Anaesth. (IF 9.1) Pub Date : 2024-04-30 Daniel Bolliger, Marco Ranucci
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Impact of intravenous dexamethasone and perineural ropivacaine on axillary block duration: analysis of two single-centre randomised trials Br. J. Anaesth. (IF 9.1) Pub Date : 2024-04-27 Francis Berthier, Emmanuel Samain, Lucie Vettoretti, Clémence Maillot, Guillaume Besch, David Ferreira
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Towards a common definition of surgical prehabilitation: a scoping review of randomised trials Br. J. Anaesth. (IF 9.1) Pub Date : 2024-04-26 Chloé Fleurent-Grégoire, Nicola Burgess, Daniel I. McIsaac, Stéphanie Chevalier, Julio F. Fiore Jr, Francesco Carli, Denny Levett, John Moore, Michael P. Grocott, Robert Copeland, Lara Edbrooke, Dominique Engel, Giuseppe Dario Testa, Linda Denehy, Chelsia Gillis
There is no universally accepted definition for surgical prehabilitation. The objectives of this scoping review were to (1) identify how surgical prehabilitation is defined across randomised controlled trials and (2) propose a common definition. The final search was conducted in February 2023 using MEDLINE, Embase, PsycINFO, Web of Science, CINAHL, and Cochrane. We included randomised controlled trials
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Modelling the economic constraints and consequences of Anaesthesia Associate expansion in the UK National Health Service. Responses to recent comments on Br J Anaesth 2024; 132: 867–876 Br. J. Anaesth. (IF 9.1) Pub Date : 2024-04-26 Jaideep J. Pandit, Stuart B. Hanmer, Mitchell H. Tsai, Daniel M. Sherrer
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Reducing airborne transmissible diseases in perioperative environments Br. J. Anaesth. (IF 9.1) Pub Date : 2024-04-26 Andrew Bowdle, Lisa M. Brosseau, Raymond Tellier, C. Raina MacIntyre, Mark Edwards, Srdjan Jelacic