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Does artificial intelligence close gaps in clinical pharmacology in the ICU? Intensive Care Med. (IF 27.1) Pub Date : 2024-12-17 Matthias Gijsen, Jan J. De Waele
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The heart–kidney axis in cirrhosis: rethinking hepatorenal and cardiorenal syndromes Intensive Care Med. (IF 27.1) Pub Date : 2024-12-16 Faeq Husain-Syed, Janani Rangaswami, Claudio Ronco, Mitchell H. Rosner, Gregorio Romero-González
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Using the ventilator to predict fluid responsiveness Intensive Care Med. (IF 27.1) Pub Date : 2024-12-16 Xavier Monnet, Daniel De Backer, Michael R. Pinsky
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Enhancing competency in ICU interns and residents through simulation-based training: a structured program in Morocco Intensive Care Med. (IF 27.1) Pub Date : 2024-12-12 Mohammed Aabdi, Khalil El Yachioui, Hamza Ghallab, Choukri Bahouh, Hicham Sbai
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Effects of delayed consent on patient characteristics in adult patients with sepsis Intensive Care Med. (IF 27.1) Pub Date : 2024-12-12 Frank Bloos, Holger Bogatsch, Mihai G. Netea, Evangelos J. Giamarellos-Bourboulis, Michael Bauer
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Considerations for β-lactam antimicrobial continuous infusion. Authors' reply to Massart et al. and Marzaroli et al. Intensive Care Med. (IF 27.1) Pub Date : 2024-12-12 Greg Barton,Claire M Rickard,Jason A Roberts
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Beta-lactam administration, which one is the best for the planet? Intensive Care Med. (IF 27.1) Pub Date : 2024-12-12 Nicolas Massart,Chloé Gisbert,Elodie Peguet,Pierre Fillatre,Pierre Bardoult
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Rethinking ARDS classification: oxygenation impairment fails to predict VILI risk Intensive Care Med. (IF 27.1) Pub Date : 2024-12-11 Giulia Catozzi, Tommaso Pozzi, Domenico Nocera, Beatrice Donati, Stefano Giovanazzi, Valentina Ghidoni, Mauro Galizia, Rosanna D’Albo, Mattia Busana, Federica Romitti, Alessandro Gatta, Onnen Moerer, Konrad Meissner, Michael Quintel, Peter Herrmann, Davide Chiumello, Luigi Camporota, Luciano Gattinoni
Purpose The selection and intensity of respiratory support for ARDS are guided by PaO2/FiO2. However, ventilator-induced lung injury (VILI) is linked to respiratory mechanics and ventilator settings. We explored whether the VILI risk is related to ARDS severity based on oxygenation. Methods We analysed data on 228 ARDS subjects with PaO2/FiO2 < 200 mmHg, categorized into three severity groups: one
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Can we use artificial intelligence to better treat acute kidney injury? Intensive Care Med. (IF 27.1) Pub Date : 2024-12-11 Greet De Vlieger, Jay L. Koyner, Marlies Ostermann
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Left diaphragmatic ultrasound in the intensive care unit: practical considerations and alternative approaches Intensive Care Med. (IF 27.1) Pub Date : 2024-12-11 Haotian Zhao, Kai Liu, Li Li, Heling Zhao
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Leveraging the power of routinely collected ICU data Intensive Care Med. (IF 27.1) Pub Date : 2024-12-11 Lada Lijović, Paul Elbers
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The role of artificial intelligence in life-sustaining treatment decisions: current state and future considerations Intensive Care Med. (IF 27.1) Pub Date : 2024-12-11 Bernhard Wernly, Bertrand Guidet, Michael Beil
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What if we do, but what if we don’t? The opportunity cost of artificial intelligence hesitancy in the intensive care unit Intensive Care Med. (IF 27.1) Pub Date : 2024-12-11 Emma-Jane Spencer, Nicoleta J. Economou-Zavlanos, Michel E. van Genderen
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When left feels right Intensive Care Med. (IF 27.1) Pub Date : 2024-12-11 Anissa Martins Bexiga, Ana Maria Portela, Stéphane Gaudry, Khalil Chaïbi
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Identifying and treating hypoactive delirium: back to square one? Authors' reply. Intensive Care Med. (IF 27.1) Pub Date : 2024-12-11 Patricia Mesa,Katarzyna Kotfis
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Invasive fungal infections and extracorporeal membrane oxygenation: a call for heightened awareness. Intensive Care Med. (IF 27.1) Pub Date : 2024-12-11 Francesco Alessandri,Antonella Tosi,Giancarlo Ceccarelli
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Hemophagocytic lymphohistiocytosis complicating severe malaria: look for hemozoin Intensive Care Med. (IF 27.1) Pub Date : 2024-12-03 Cassilia Dei, Capucine Belcadi, Jean Dellamonica, Denis Doyen
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How to manage sodium-glucose cotransporter-2 inhibitors in the critically ill patient? Intensive Care Med. (IF 27.1) Pub Date : 2024-12-02 Bruno Garcia, Marlies Ostermann, Matthieu Legrand
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A farewell as Editor-in-Chief: reflecting on the evolution of Intensive Care Medicine over the last 18 years. Intensive Care Med. (IF 27.1) Pub Date : 2024-12-01 Giuseppe Citerio
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Personalizing beta-blockade in septic shock: finding the right rhythm and rate for the right patient. Intensive Care Med. (IF 27.1) Pub Date : 2024-11-26 František Duška,Sebastian Rehberg
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Rethinking energy and protein provision for critically ill patients Intensive Care Med. (IF 27.1) Pub Date : 2024-11-25 Christian Stoppe, Emma J. Ridley, Zheng-Yii Lee
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Heart rate control in septic shock-echocardiographic evaluation and monitoring should be standard. Intensive Care Med. (IF 27.1) Pub Date : 2024-11-25 Sebastian Rehberg,Frantisek Duska
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Terlipressin use in hepatorenal syndrome-acute kidney injury in cirrhosis. Author's reply. Intensive Care Med. (IF 27.1) Pub Date : 2024-11-21 Mitra K Nadim,Lui G Forni,Marlies Ostermann,
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Optimizing ICU weaning: globalizing personalized weaning strategies. Intensive Care Med. (IF 27.1) Pub Date : 2024-11-21 Chenglong Liang,Chen Zhou,Jingye Pan
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Artificial Intelligence interpretation of chest radiographs in intensive care. Ready for prime time? Intensive Care Med. (IF 27.1) Pub Date : 2024-11-20 Leo Joskowicz, Michael Beil, Sigal Sviri
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[18F]FDG PET/CT to diagnose inflammation in critically ill immunocompromised patients. Intensive Care Med. (IF 27.1) Pub Date : 2024-11-20 B van Leer,C P van Stee,A W J M Glaudemans,G J Westland,J Pillay
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Individualized response to awake prone positioning in COVID-19 patients: need deeper insights. Intensive Care Med. (IF 27.1) Pub Date : 2024-11-20 Ling Liu,Qin Sun,Yi Yang,Haibo Qiu,Arthur S Slutsky
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Position paper on the physiology and nomenclature of dual circulation during venoarterial ECMO in adults Intensive Care Med. (IF 27.1) Pub Date : 2024-11-18 Jenelle Badulak, Darryl Abrams, Andrew M. Luks, Bishoy Zakhary, Steven A. Conrad, Robert Bartlett, Graeme MacLaren, Leen Vercaemst, Roberto Lorusso, Lars Mikael Broman, Cara Agerstrand, Susanna Price, Alain Combes, Giles Peek, Eddy Fan, Kiran Shekar, John Fraser, Daniel Brodie
When native blood flow through the aorta from the adult heart and lungs meets retrograde blood flow from an artificial heart and lung during venoarterial extracorporeal membrane oxygenation (VA-ECMO), the result is the creation of two separate circulations on either side of the blood flow mixing point. This phenomenon is known as dual circulation and is characterized by different content of oxygen
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Early physiologic changes after awake prone positioning predict clinical outcomes in patients with acute hypoxemic respiratory failure Intensive Care Med. (IF 27.1) Pub Date : 2024-11-14 Matias Olmos, Mariano Esperatti, Nora Fuentes, Anabel Miranda Tirado, María Eugenia Gonzalez, Hiromi Kakisu, Juan Suarez, Manuel Tisminetzky, Veronica Barbaresi, Ignacio Santomil, Alejandro Bruhn Cruz, Domenico Luca Grieco, Bruno L. Ferreyro
Purpose The optimal physiologic parameters to monitor after a session of awake prone positioning in patients with acute respiratory failure are not well understood. This study aimed to identify which early physiologic changes after the first session of awake prone positioning are linked to the need for invasive mechanical ventilation or death in patients with acute respiratory failure. Methods We performed
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Chlorhexidine-alcohol compared with povidone-iodine-alcohol skin antisepsis protocols in major cardiac surgery: a randomized clinical trial Intensive Care Med. (IF 27.1) Pub Date : 2024-11-12 Matthieu Boisson, Géraldine Allain, Jean-Christian Roussel, Nicolas d’Ostrevy, Silvia Burbassi, Pierre Demondion, Paul-Michel Mertes, François Labaste, Thomas Kerforne, Bertrand Rozec, Vedat Eljezi, Konstantinos Zannis, Pascal Leprince, Walid Oulehri, Vincent Minville, Sabrina Seguin, Ambre Loiodice, Stéphane Ruckly, Jean-Christophe Lucet, Jean-François Timsit, Olivier Mimoz
Purpose Whether skin disinfection of the surgical site using chlorhexidine-alcohol is superior to povidone-iodine-alcohol in reducing reoperation and surgical site infection rates after major cardiac surgery remains unclear. Methods CLEAN 2 was a multicenter, open-label, randomized, two-arm, assessor-blind, superiority trial conducted in eight French hospitals. We randomly assigned adult patients undergoing
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Sepsis: key insights, future directions, and immediate goals. A review and expert opinion Intensive Care Med. (IF 27.1) Pub Date : 2024-11-12 Ignacio Martin-Loeches, Mervyn Singer, Marc Leone
This review explores the current landscape and evolving understanding of sepsis, highlighting both challenges and future directions. Sepsis remains a major global health burden, with diverse clinical presentations complicating timely diagnosis and management. Existing definitions, including the Sepsis-3 criteria, emphasize the importance of organ dysfunction, yet early sepsis detection remains limited
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Air pollutant exposure and mortality risk of critically ill patients Intensive Care Med. (IF 27.1) Pub Date : 2024-11-12 Chen Li, Huzhi Yao, Zhanpeng Wang, Zhicheng Fang, Peng Jia, Jingjun Lv
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Beta-blockers as antiarrhythmics in septic shock: a light at the end of the tunnel? Intensive Care Med. (IF 27.1) Pub Date : 2024-11-12 Martin Balik, G. Tavazzi, M. Slama
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Fludrocortisone with hydrocortisone in sepsis: new evidence in an ongoing debate. Intensive Care Med. (IF 27.1) Pub Date : 2024-11-12 Otavio Ranzani,Djillali Annane,Mervyn Singer
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Personalized positive end-expiratory pressure in spontaneously breathing patients with acute respiratory distress syndrome by simultaneous electrical impedance tomography and transpulmonary pressure monitoring: a randomized crossover trial Intensive Care Med. (IF 27.1) Pub Date : 2024-11-11 Tommaso Mauri, Domenico L. Grieco, Elena Spinelli, Marco Leali, Joaquin Perez, Valentina Chiavieri, Tommaso Rosà, Pierluigi Ferrara, Gaetano Scaramuzzo, Massimo Antonelli, Savino Spadaro, Giacomo Grasselli
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Landiolol in patients with septic shock. Intensive Care Med. (IF 27.1) Pub Date : 2024-11-11 Vassilios Vazgiourakis,Konstantinos Mantzarlis,Demosthenes Makris
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Heart rate control in septic shock-"every journey begins with a first step" (Confucius). Intensive Care Med. (IF 27.1) Pub Date : 2024-11-11 Sebastian Rehberg,Frantisek Duska
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End-of-life care awareness in a low-middle-income country: a plea for improvement. Intensive Care Med. (IF 27.1) Pub Date : 2024-11-11 Radhouane Toumi,Mohamed Boussarsar
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Identifying and treating hypoactive delirium: back to square one? Intensive Care Med. (IF 27.1) Pub Date : 2024-11-06 Julia Tavares-Pereira, Luísa Pereira Novaes, Mariana Luz, Bruna Brandao Barreto, Dimitri Gusmao-Flores
No Abstract
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Comment on: European Society of Intensive Care Medicine guidelines on end of life and palliative care in the intensive care unit. Intensive Care Med. (IF 27.1) Pub Date : 2024-11-06 Michael J. O’Leary
The European Society of Intensive Care Medicine, through its multi-disciplinary panel, is to be congratulated for developing fairly comprehensive guidelines on end-of-life and palliative care in the intensive care unit, which highlight the poor quality of evidence and the need for research in these domains [1]. Unfortunately, there is a significant and important omission in these guidelines which is
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Central venous catheter insertion site and infection prevention in 2024. Author’s reply Intensive Care Med. (IF 27.1) Pub Date : 2024-11-04 Nicolas Massart, Vincent Cosme, Florian Reizine, Arnaud Friggeri, Alain Lepape
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Non-synchronized unassisted spontaneous ventilation may minimize the risk of high global tidal volume and transpulmonary pressure, but it is not free from pendelluft Intensive Care Med. (IF 27.1) Pub Date : 2024-11-04 Rodrigo A. Cornejo, Roberto Brito, Daniel H. Arellano, Caio C. A. Morais
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Reflections on awake prone positioning in COVID-19: considerations on body inclination, respiratory support, and patient variability Intensive Care Med. (IF 27.1) Pub Date : 2024-11-04 Yuxian Wang, Shengyu Hao, Jieqiong Song, Ming Zhong
No Abstract
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Optimizing meropenem infusion: the importance of concentration and stability Intensive Care Med. (IF 27.1) Pub Date : 2024-11-04 Matteo Marzaroli, Alberto Zangrillo, Giacomo Monti
No Abstract
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The nature of clinical research: even a clear answer gives rise to many other questions Intensive Care Med. (IF 27.1) Pub Date : 2024-11-04 Michael C. Reade, David Liu
No Abstract
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Skin decontamination to prevent infections in the intensive care unit Intensive Care Med. (IF 27.1) Pub Date : 2024-10-31 Marc Bonten, Bruno Martins Tomazini, Stephan Harbarth
Intensive care unit (ICU)-acquired infections can be serious complications of medical care of critically ill patients. Despite multiple tested and implemented preventive measures for such infections, their incidence is persistently high, whereas coherence of infection prevention practices in ICUs across the globe remains low. The heterogeneity in practice reflects the—perceived—low level of evidence
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Protocolized fluid balance neutralization during continuous renal replacement therapy Intensive Care Med. (IF 27.1) Pub Date : 2024-10-31 Raghavan Murugan, John Prowle, William Beaubien-Souligny
International guidelines recommend net extracorporeal fluid removal (i.e., net ultrafiltration [UFNET]) for critically ill patients with oliguric acute kidney injury (AKI) and fluid overload [1]. However, the optimal approach to UFNET remains unclear, with significant global variation in clinical practice [2, 3]. Key uncertainties include when to initiate fluid removal, the appropriate volume and rate
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Preventing ventilator-associated pneumonia non-pharmacologically Intensive Care Med. (IF 27.1) Pub Date : 2024-10-30 Manuel Krone, Christian Seeber, Peter Nydahl
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Managing blood glucose control in the intensive care unit Intensive Care Med. (IF 27.1) Pub Date : 2024-10-29 Jan Gunst, Guillermo E. Umpierrez, Greet Van den Berghe
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How I perform diaphragmatic ultrasound in the intensive care unit Intensive Care Med. (IF 27.1) Pub Date : 2024-10-29 Greet Hermans, Alexandre Demoule, Leo Heunks
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Is fludrocortisone the missing piece in septic shock? A closer look. Author's reply Intensive Care Med. (IF 27.1) Pub Date : 2024-10-29 James Walsham, Balasubramanian Venkatesh
No Abstract
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Utilization and outcomes of extracorporeal membrane oxygenation in patients with cirrhosis Intensive Care Med. (IF 27.1) Pub Date : 2024-10-29 Spencer R. Goble, Yasmin O. Ali, Thomas M. Leventhal
No Abstract
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Critical care admissions and outcomes in pregnant and postpartum women: a systematic review Intensive Care Med. (IF 27.1) Pub Date : 2024-10-28 Swagata Tripathy, Neha Singh, Aparajita Panda, Subhasish Nayak, Nivedita Jayanti Bodra, Suma Rabab Ahmad, Madhusmita Parida, Monalisa Sarkar, Soumya Sarkar
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Implementation of a novel retrograde implantation technique for distal limb perfusion during extracorporeal cardiopulmonary resuscitation Intensive Care Med. (IF 27.1) Pub Date : 2024-10-28 Yalin Yildirim, Stefan Kluge, Hermann Reichenspurner, Alexander M. Bernhardt, Simon Pecha
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The paracetamol challenge in intensive care: going green with paracetamol Intensive Care Med. (IF 27.1) Pub Date : 2024-10-28 Nicole Hunfeld, Dick Tibboel, Diederik Gommers
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Interventions to reduce low-value care in intensive care settings: a scoping review of impacts on health, resource use, costs, and the environment Intensive Care Med. (IF 27.1) Pub Date : 2024-10-25 Jake T. W. Williams, Florencia Moraga Masson, Forbes McGain, Rachel Stancliffe, Julia K. Pilowsky, Nhi Nguyen, Katy J. L. Bell
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Spontaneous breathing trials should be adapted for each patient according to the critical illness. A new individualised approach: the GLOBAL WEAN study Intensive Care Med. (IF 27.1) Pub Date : 2024-10-25 Mathieu Capdevila, Yassir Aarab, Clement Monet, Audrey De Jong, Aurelie Vonarb, Julie Carr, Nicolas Molinari, Xavier Capdevila, Laurent Brochard, Samir Jaber
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My echo checklist in venoarterial ECMO patients Intensive Care Med. (IF 27.1) Pub Date : 2024-10-25 Ouriel Saura, Alain Combes, Guillaume Hekimian
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Heart rate control in septic shock with tachycardia Intensive Care Med. (IF 27.1) Pub Date : 2024-10-25 Ajay Kumar Jha
No Abstract
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Integrating multidisciplinary expertise in postoperative noninvasive ventilation management. Authors’ reply Intensive Care Med. (IF 27.1) Pub Date : 2024-10-25 Audrey De Jong, Joris Pensier, Samir Jaber
No Abstract