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Plant-produced SARS-CoV-2 antibody engineered towards enhanced potency and in vivo efficacy Plant Biotech. J. (IF 10.1) Pub Date : 2024-11-19 Steven W. de Taeye, Loïc Faye, Bertrand Morel, Angela I. Schriek, Jeffrey C. Umotoy, Meng Yuan, Natalia A. Kuzmina, Hannah L. Turner, Xueyong Zhu, Clemens Grünwald-Gruber, Meliawati Poniman, Judith A. Burger, Tom G. Caniels, Anne-Catherine Fitchette, Réjean Desgagnés, Virginie Stordeur, Lucie Mirande, Guillaume Beauverger, Godelieve de Bree, Gabriel Ozorowski, Andrew B. Ward, Ian A. Wilson, Alexander
Prevention of severe COVID-19 disease by SARS-CoV-2 in high-risk patients, such as immuno-compromised individuals, can be achieved by administration of antibody prophylaxis, but producing antibodies can be costly. Plant expression platforms allow substantial lower production costs compared to traditional bio-manufacturing platforms depending on mammalian cells in bioreactors. In this study, we describe
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Residential Garden Produce Harvested Near a Fluorochemical Manufacturer in North Carolina Can Be An Important Fluoroether Exposure Pathway J. Agric. Food Chem. (IF 5.7) Pub Date : 2024-11-20 Pingping Meng, Nadia Sheppard, Sarangi Joseph, Owen W. Duckworth, Christopher P. Higgins, Detlef R. U. Knappe
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Fisetin Ameliorates Hepatocyte Lipid Droplet Accumulation via Targeting the Rhythmic Protein BMAL1 to Regulate Cell Death-Inducing DNA Fragmentation Factor-α-like Effector C-Mediated Lipid Droplet Fusion J. Agric. Food Chem. (IF 5.7) Pub Date : 2024-11-20 Ranran Zhang, Meitong Liu, Jing Lu, Shujing Lu, Yuanmeng Wang, Shuang Guan
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Comparative Study on the Antioxidative Effects and α-Glucosidase Inhibitory Potential In Vitro among Ellagic Acid and Its Metabolites Urolithins J. Agric. Food Chem. (IF 5.7) Pub Date : 2024-11-20 Zhao-Rong Li, Rui-Bo Jia, Yurong Mo, Haozheng Wang, Donghui Luo, Chunxia Zhou, Mouming Zhao
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Effect of Different Addition Amounts of Capsaicin on the Structure, Oxidation Sites, and Gel Properties of Myofibrillar Proteins under Oxidative Conditions J. Agric. Food Chem. (IF 5.7) Pub Date : 2024-11-20 Dong Zhang, Zhi-Cheng Wu, Jing-Bing Xu, Nan-Xi Huang, Yong Tang, Chang Su, Jie Tang, Hong-Jun Li
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Tryptophan Metabolism-Regulating Probiotics Alleviate Hyperuricemia by Protecting the Gut Barrier Integrity and Enhancing Colonic Uric Acid Excretion J. Agric. Food Chem. (IF 5.7) Pub Date : 2024-11-20 Qianxu Wang, Jiarui Liang, Qianhui Zou, Wenxiu Wang, Guiming Yan, Rui Guo, Tian Yuan, Yutang Wang, Xuebo Liu, Zhigang Liu
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Real-Time In Situ Tracking of the Penetration and Uptake Behavior of Nano-pesticides in Tea Plants Using Surface-Enhanced Raman Spectroscopy J. Agric. Food Chem. (IF 5.7) Pub Date : 2024-11-20 Xinyi Wang, Qing Wang, Chuanjian Cui, Min Yan, Wanjun Gao, Wenchao Li, Guozhong Wang, Hongjian Zhou, Ruyan Hou
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Anthraquinone Residues in Dried Walnut (Juglans regia) Leaves for Herbal Infusions: Proof of Endogenous Origin via a Sampling-Driven and GC-MS/MS-Based Strategy J. Agric. Food Chem. (IF 5.7) Pub Date : 2024-11-20 Lucas Ferrando Plo, Athanasios Nitsopoulos, Albrecht Friedle, Andreas Schmidberger, Jörg Heilmann
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Development and Application of a New QuEChERS Method Coupled with UPLC-QTOF-MS/MS for Analysis of Tiafenacil and Its Photolysis Products in Water J. Agric. Food Chem. (IF 5.7) Pub Date : 2024-11-19 Zhie Zhou, Shujie Zhang, Jian Chen, Wenjing Luo, Fenfen Kang, Yonglin Ren, Wenwen Zhou
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1,3-Dichloro-2-propanol Induced Renal Cell Ferroptosis via the Circadian Clock Protein BMAL1 Targeting GPX4 J. Agric. Food Chem. (IF 5.7) Pub Date : 2024-11-19 Yuelin Chen, Shuang Guan, Meitong Liu, Lingxi Lang, Huanhuan Peng, Jing Lu
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Exploring the Biological Potential of Hydroxytyrosol and Derivatives: Synthetic Strategies and Evaluation of Antiproliferative, Antioxidant, and Antimicrobial Activities J. Agric. Food Chem. (IF 5.7) Pub Date : 2024-11-19 Beatriz T. Martins, Nuno Alexandre Faria, Ana Catarina Macedo, Maria Miragaia, Ana Teresa Serra, M. Rosário Bronze, M. Rita Ventura
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A Mechanistic Approach on Perception Mode of ABA Receptors (PYLs) to Novel Opabactin Analogues J. Agric. Food Chem. (IF 5.7) Pub Date : 2024-11-19 Xianjun Tang, Minghui Chen, Xiaobin Li, Huizhe Lu, Xueqin Zhang, Yiyi Li, Jiaqi Li, Yumei Xiao, Zhaohai Qin
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Flavin-Dependent Monooxgenase Confers Resistance to Chlorantraniliprole and Spinetoram in the Rice Stem Borer Chilo suppressalis Walker (Lepidoptera: Crambidae) J. Agric. Food Chem. (IF 5.7) Pub Date : 2024-11-19 Shuai Wang, Jing-Mei Huang, Fang-Rui Guo, Chong Liu, Yuan Xie, Song-Tao Qiao, Yun-Xiao Chen, Shun-Fan Wu, Chris Bass, Cong-Fen Gao
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Comparative study on the physicochemical characteristics of lignin via sequential solvent fractionation of ethanol and Kraft lignin derived from poplar and their applications Ind. Crops Prod. (IF 5.6) Pub Date : 2024-11-20 Changgeng Li, Zhongshan Wang, Minjie Hou, Xinyu Cao, Wenchao Jia, Lingzhi Huang, Lu Wu, Bing Wang, Xueru Sheng, Yanzhu Guo, Haiqiang Shi
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Forest fertilization transiently increases soil CO2 efflux in young Norway spruce stands in Sweden Agric. For. Meteorol. (IF 5.6) Pub Date : 2024-11-20 Charlotta Håkansson, Per-Ola Hedwall, Martin Karl-Friedrich Bader, Monika Strömgren, Magnus Axelsson, Johan Bergh
Late-rotation fertilization of Norway spruce stands is a frequently used management tool in Fennoscandia to increase timber yields. Meanwhile, the growing demand for renewable resources has sparked great interest in earlier and repeated fertilizer application but it remains unclear how this affects carbon dioxide (CO2) fluxes in the understory, especially forest floor respiration (Rff). This study
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Half of the top 20 science cities are now in China — and regional city growth is the key Nature (IF 50.5) Pub Date : 2024-11-20
The country’s research progress means its cities might lead in all Nature Index subjects within a decade.
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China’s regional cities are now major players in world science Nature (IF 50.5) Pub Date : 2024-11-20
Provincial capitals such as Hefei are outscoring some established science cities in the Nature Index — here’s why.
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Leading Nature Index science cities in health sciences: US institutions power country’s growth Nature (IF 50.5) Pub Date : 2024-11-20
European cities make their mark while the United States extends its lead.
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A guide to the Nature Index Nature (IF 50.5) Pub Date : 2024-11-20
A description of the terminology and methodology used in this supplement, and a guide to the functionality that is available free online at natureindex.com.
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Leading Nature Index science cities in biological sciences: collaboration powers US research Nature (IF 50.5) Pub Date : 2024-11-20
Although the United States maintains a steady lead, Chinese cities are on the rise.
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How students and grandparents could solve the global mental-health crisis Nature (IF 50.5) Pub Date : 2024-11-20
African researchers piloted a slew of innovative, low-cost programmes for addressing the troubling shortage of mental-health professionals on the continent. Now the rest of the world is taking notice.
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How being multilingual both helps and hinders me and my science Nature (IF 50.5) Pub Date : 2024-11-20
Although I find new ways to express myself as a student abroad, sometimes it can be isolating to avoid my mother tongue, writes Rahul Roy.
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Ferocity of Atlantic hurricanes surges as the ocean warms Nature (IF 50.5) Pub Date : 2024-11-20
Climate change has driven hurricane wind speeds up by an average of nearly 30 kilometres per hour, an analysis of Atlantic storms shows.
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Leading Nature Index science cities in chemistry: China positions for clean sweep Nature (IF 50.5) Pub Date : 2024-11-20
Although Beijing has solidified its top spot in the standings, the country’s regional cities are ones to watch.
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Boston’s dense health-sciences networks help the city to maintain its lead Nature (IF 50.5) Pub Date : 2024-11-20
But Chinese cities are quickly rising, thanks to significant government investment and targeted legislation.
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Should I climb the career ladder as a manager, or will I regret leaving the lab bench behind? Nature (IF 50.5) Pub Date : 2024-11-20
I’m not sure if a management role in science is for me. How do I decide?
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How ‘Made in China 2025’ helped supercharge scientific development in China’s cities Nature (IF 50.5) Pub Date : 2024-11-20
The policy has boosted tech transfer and economic growth in some regions, but challenges remain around innovation in key technologies.
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Leading Nature Index science cities in Earth and environmental science: Research output gathers pace in China Nature (IF 50.5) Pub Date : 2024-11-20
The country’s rising players outperform US cities in year-on-year growth.
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Leading Nature Index science cities in physical sciences: regional centres drive China’s progress Nature (IF 50.5) Pub Date : 2024-11-20
Impressive year-on-year growth has seen smaller hubs climb the list — but eyes remain on Beijing.
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Single-molecule states link transcription factor binding to gene expression Nature (IF 50.5) Pub Date : 2024-11-20 Benjamin R. Doughty, Michaela M. Hinks, Julia M. Schaepe, Georgi K. Marinov, Abby R. Thurm, Carolina Rios-Martinez, Benjamin E. Parks, Yingxuan Tan, Emil Marklund, Danilo Dubocanin, Lacramioara Bintu, William J. Greenleaf
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Cephalopod-inspired jetting devices for gastrointestinal drug delivery Nature (IF 50.5) Pub Date : 2024-11-20 G. Arrick, D. Sticker, A. Ghazal, Y. Lu, T. Duncombe, D. Gwynne, B. Mouridsen, J. Wainer, J. P. H. Jepsen, T. S. Last, D. Schultz, K. Hess, E. Medina De Alba, S. Min, M. Poulsen, C. Anker, P. Karandikar, H. D. Pedersen, J. Collins, N. E. Egecioglu, S. Tamang, C. Cleveland, K. Ishida, A. H. Uhrenfeldt, J. Kuosmanen, M. Pereverzina, A. Hayward, R. K. Kirk, S. You, C. M. Dalsgaard, S. B. Gunnarsson, I
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Direct magnetic imaging of fractional Chern insulators in twisted MoTe2 Nature (IF 50.5) Pub Date : 2024-11-20 Evgeny Redekop, Canxun Zhang, Heonjoon Park, Jiaqi Cai, Eric Anderson, Owen Sheekey, Trevor Arp, Grigory Babikyan, Samuel Salters, Kenji Watanabe, Takashi Taniguchi, Martin E. Huber, Xiaodong Xu, Andrea F. Young
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Nonlinear receptive fields evoke redundant retinal coding of natural scenes Nature (IF 50.5) Pub Date : 2024-11-20 Dimokratis Karamanlis, Mohammad H. Khani, Helene M. Schreyer, Sören J. Zapp, Matthias Mietsch, Tim Gollisch
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A functional microbiome catalogue crowdsourced from North American rivers Nature (IF 50.5) Pub Date : 2024-11-20 Mikayla A. Borton, Bridget B. McGivern, Kathryn R. Willi, Ben J. Woodcroft, Annika C. Mosier, Derick M. Singleton, Ted Bambakidis, Aaron Pelly, Rebecca A. Daly, Filipe Liu, Andrew Freiburger, Janaka N. Edirisinghe, José P. Faria, Robert Danczak, Ikaia Leleiwi, Amy E. Goldman, Michael J. Wilkins, Ed K. Hall, Christa Pennacchio, Simon Roux, Emiley A. Eloe-Fadrosh, Stephen P. Good, Matthew B. Sullivan
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Examining the role of common variants in rare neurodevelopmental conditions Nature (IF 50.5) Pub Date : 2024-11-20 Qin Qin Huang, Emilie M. Wigdor, Daniel S. Malawsky, Patrick Campbell, Kaitlin E. Samocha, V. Kartik Chundru, Petr Danecek, Sarah Lindsay, Thomas Marchant, Mahmoud Koko, Sana Amanat, Davide Bonfanti, Eamonn Sheridan, Elizabeth J. Radford, Jeffrey C. Barrett, Caroline F. Wright, Helen V. Firth, Varun Warrier, Alexander Strudwick Young, Matthew E. Hurles, Hilary C. Martin
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A multi-omic atlas of human embryonic skeletal development Nature (IF 50.5) Pub Date : 2024-11-20 Ken To, Lijiang Fei, J. Patrick Pett, Kenny Roberts, Raphael Blain, Krzysztof Polański, Tong Li, Nadav Yayon, Peng He, Chuan Xu, James Cranley, Madelyn Moy, Ruoyan Li, Kazumasa Kanemaru, Ni Huang, Stathis Megas, Laura Richardson, Rakesh Kapuge, Shani Perera, Elizabeth Tuck, Anna Wilbrey-Clark, Ilaria Mulas, Fani Memi, Batuhan Cakir, Alexander V. Predeus, David Horsfall, Simon Murray, Martin Prete,
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An integrated transcriptomic cell atlas of human neural organoids Nature (IF 50.5) Pub Date : 2024-11-20 Zhisong He, Leander Dony, Jonas Simon Fleck, Artur Szałata, Katelyn X. Li, Irena Slišković, Hsiu-Chuan Lin, Malgorzata Santel, Alexander Atamian, Giorgia Quadrato, Jieran Sun, Sergiu P. Pașca, J. Gray Camp, Fabian J. Theis, Barbara Treutlein
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Gliocidin is a nicotinamide-mimetic prodrug that targets glioblastoma Nature (IF 50.5) Pub Date : 2024-11-20 Yu-Jung Chen, Swathi V. Iyer, David Chun-Cheng Hsieh, Buren Li, Harold K. Elias, Tao Wang, Jing Li, Mungunsarnai Ganbold, Michelle C. Lien, Yu-Chun Peng, Xuanhua P. Xie, Chenura D. Jayewickreme, Marcel R. M. van den Brink, Sean F. Brady, S. Kyun Lim, Luis F. Parada
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Local probe of bulk and edge states in a fractional Chern insulator Nature (IF 50.5) Pub Date : 2024-11-20 Zhurun Ji, Heonjoon Park, Mark E. Barber, Chaowei Hu, Kenji Watanabe, Takashi Taniguchi, Jiun-Haw Chu, Xiaodong Xu, Zhi-Xun Shen
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Human HDAC6 senses valine abundancy to regulate DNA damage Nature (IF 50.5) Pub Date : 2024-11-20 Jiali Jin, Tong Meng, Yuanyuan Yu, Shuheng Wu, Chen-Chen Jiao, Sihui Song, Ya-Xu Li, Yu Zhang, Yuan-Yuan Zhao, Xinran Li, Zixin Wang, Yu-Fan Liu, Runzhi Huang, Jieling Qin, Yihua Chen, Hao Cao, Xiao Tan, Xin Ge, Cong Jiang, Jianhuang Xue, Jian Yuan, Dianqing Wu, Wei Wu, Ci-Zhong Jiang, Ping Wang
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Single-cell integration reveals metaplasia in inflammatory gut diseases Nature (IF 50.5) Pub Date : 2024-11-20 Amanda J. Oliver, Ni Huang, Raquel Bartolome-Casado, Ruoyan Li, Simon Koplev, Hogne R. Nilsen, Madelyn Moy, Batuhan Cakir, Krzysztof Polanski, Victoria Gudiño, Elisa Melón-Ardanaz, Dinithi Sumanaweera, Daniel Dimitrov, Lisa Marie Milchsack, Michael E. B. FitzPatrick, Nicholas M. Provine, Jacqueline M. Boccacino, Emma Dann, Alexander V. Predeus, Ken To, Martin Prete, Jonathan A. Chapman, Andrea C. Masi
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Gut microbiome strain-sharing within isolated village social networks Nature (IF 50.5) Pub Date : 2024-11-20 Francesco Beghini, Jackson Pullman, Marcus Alexander, Shivkumar Vishnempet Shridhar, Drew Prinster, Adarsh Singh, Rigoberto Matute Juárez, Edoardo M. Airoldi, Ilana L. Brito, Nicholas A. Christakis
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A giant planet transiting a 3-Myr protostar with a misaligned disk Nature (IF 50.5) Pub Date : 2024-11-20 Madyson G. Barber, Andrew W. Mann, Andrew Vanderburg, Daniel Krolikowski, Adam Kraus, Megan Ansdell, Logan Pearce, Gregory N. Mace, Sean M. Andrews, Andrew W. Boyle, Karen A. Collins, Matthew De Furio, Diana Dragomir, Catherine Espaillat, Adina D. Feinstein, Matthew Fields, Daniel Jaffe, Ana Isabel Lopez Murillo, Felipe Murgas, Elisabeth R. Newton, Enric Palle, Erica Sawczynec, Richard P. Schwarz,
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Social state alters vision using three circuit mechanisms in Drosophila Nature (IF 50.5) Pub Date : 2024-11-20 Catherine E. Schretter, Tom Hindmarsh Sten, Nathan Klapoetke, Mei Shao, Aljoscha Nern, Marisa Dreher, Daniel Bushey, Alice A. Robie, Adam L. Taylor, Kristin Branson, Adriane Otopalik, Vanessa Ruta, Gerald M. Rubin
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Mineralized collagen plywood contributes to bone autograft performance Nature (IF 50.5) Pub Date : 2024-11-20 Marc Robin, Elodie Mouloungui, Gabriel Castillo Dali, Yan Wang, Jean-Louis Saffar, Graciela Pavon-Djavid, Thibaut Divoux, Sébastien Manneville, Luc Behr, Delphine Cardi, Laurence Choudat, Marie-Madeleine Giraud-Guille, Anne Meddahi-Pellé, Fannie Baudimont, Marie-Laure Colombier, Nadine Nassif
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Combining quantum processors with real-time classical communication Nature (IF 50.5) Pub Date : 2024-11-20 Almudena Carrera Vazquez, Caroline Tornow, Diego Ristè, Stefan Woerner, Maika Takita, Daniel J. Egger
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Revised historical record sharpens perspective on global warming Nature (IF 50.5) Pub Date : 2024-11-20 Timothy J. Osborn, John J. Kennedy
Undercorrection of ocean surface temperatures revealed.
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A ‘Wikipedia for cells’: researchers get an updated look at the Human Cell Atlas, and it’s remarkable Nature (IF 50.5) Pub Date : 2024-11-20
Coming less than a decade after its launch, the studies emerging from the global project are a major achievement. Funders should sign up for the long haul.
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Common genetic variants contribute more to rare diseases than previously thought Nature (IF 50.5) Pub Date : 2024-11-20 Gerome Breen
Assessing the influence of common mutations on rare disease risk.
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When is a soil too dry for plants to take up water? Nature (IF 50.5) Pub Date : 2024-11-20
The hydraulics of sandy soils make their ecosystems more sensitive to soil drying.
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Quantum computing: physics–AI collaboration quashes quantum errors Nature (IF 50.5) Pub Date : 2024-11-20 Nadia Haider
Machine-learning strategy for quantum error correction.
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How a fly’s behavioural state affects its view of the world Nature (IF 50.5) Pub Date : 2024-11-20
Neurons in the fruit-fly brain gate the flow of visual information depending on behavioural context.
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Cellular atlases are unlocking the mysteries of the human body Nature (IF 50.5) Pub Date : 2024-11-20 Itai Yanai, Simon Haas, Christoph Lippert, Helene Kretzmer
Scientists reflect on insights from the Human Cell Atlas.
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Computational technologies of the Human Cell Atlas Nature (IF 50.5) Pub Date : 2024-11-20
As the international effort reaches a ‘critical mass’ of achievements, Nature highlights seven tools that are poised to enable the next set of discoveries.
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Human antibodies offer broad inhibition against variable proteins of the malaria parasite Nature (IF 50.5) Pub Date : 2024-11-20 Tuan M. Tran
Antibodies from malaria-exposed individuals target diverse proteins.
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Squid-inspired jet devices deliver drugs without a need for needles Nature (IF 50.5) Pub Date : 2024-11-20
Systems that mimic cephalopods can jet drugs into the gastrointestinal tract.
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Newborn planet found in a warped system Nature (IF 50.5) Pub Date : 2024-11-20
The discovery of a young, Jupiter-sized planet with a short orbital period provides useful data for studying planet formation.
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Catalysts degrade forever chemicals with visible light Nature (IF 50.5) Pub Date : 2024-11-20 Jinyong Liu
Low-energy processes break down persistent pollutants.
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Leon Cooper obituary: Nobel laureate who developed theory of superconductivity Nature (IF 50.5) Pub Date : 2024-11-19
The condensed-matter physicist also turned his attention to neural networks, improving our understanding of the human brain and helping to develop machine learning.