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Three Molecular Developmental Pathways of Remnant Pancreatic Cancer after Resection: A Nationwide Project Study of Japan Pancreas Society. Ann. Surg. (IF 7.5) Pub Date : 2024-07-17 Shuji Suzuki, Yuko Omori, Yusuke Ono, Katsuya Hirose, Taito Itoh, Hidenori Karasaki, Mitsugi Shimoda, Yuichi Nagakawa, Ryota Higuchi, Itaru Endo, Toshiki Rikiyama, Michiaki Unno, Tsutomu Fujii, Yuki Sunagawa, Hidetoshi Eguchi, Hideki Sasanuma, Takahiro Akahori, Keiichi Okano, Masaji Tani, Satoshi Hirano, Yasuhiro Shimizu, Minoru Kitago, Shugo Mizuno, Tomohisa Yamamoto, Masayuki Furukawa, Masayuki Ohtsuka
This study aimed to clarify the molecular mechanism of remnant pancreatic cancer (PC) development after primary PC resection.
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Introducing Neoadjuvant Immunotherapy for Colorectal Cancer: Advancing the Frontier. Ann. Surg. (IF 7.5) Pub Date : 2024-07-15 Adile Orhan, Tobias F Justesen, Hans Raskov, Camilla Qvortrup, Ismail Gögenur
To give surgeons a review of the current and future use of neoadjuvant immunotherapy in patients with localized colorectal cancer.
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Randomized Controlled Trial Comparison of Clinical Outcomes and Postoperative Nutritional Status Between Early and Late Oral Feeding After Esophagectomy: An Open Labeled Randomized Controlled Trial. Ann. Surg. (IF 7.5) Pub Date : 2024-07-12 Kwon Joong Na, Chang Hyun Kang, Young Ran Kim, Mi Jin Kang, Eun Hwa Song, Eun Joo Jang, Samina Park, Hyun Joo Lee, In Kyu Park, Young Tae Kim
To compare nutritional and postoperative outcomes between early oral feeding and late oral feeding with jejunostomy feeding support after esophagectomy.
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Association of Surgeon Self-Reported Gender and Surgical Outcomes in Current U.S. Practice. Ann. Surg. (IF 7.5) Pub Date : 2024-07-12 Salvatore T Scali, Jesse A Columbo, Mary T Hawn, Erica L Mitchell, Dan Neal, Sandra L Wong, Thomas S Huber, Gilbert R Upchurch, David H Stone
This study aimed to evaluate the association of surgeon self-reported gender on clinical outcomes in contemporary U.S. surgical practice.
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Risk Factor Targeted Perioperative Care Reduces Anastomotic Leakage after Colorectal Surgery: The DoubleCheck study. Ann. Surg. (IF 7.5) Pub Date : 2024-07-11 Anne de Wit, Boukje T Bootsma, Daitlin E Huisman, Bob van Wely, Julie van Hoogstraten, Dirk J A Sonneveld, Daan Moes, Johannes A Wegdam, Carlo V Feo, Emiel G G Verdaasdonk, Walter J A Brokelman, David W G Ten Cate, Tim Lubbers, Emmanuel Lagae, David J G H Roks, Geert Kazemier, Jurre Stens, Gerrit D Slooter, Freek Daams
The DoubleCheck study aimed to introduce pre- and perioperative interventions minimizing exposure to modifiable risk factors and determine its effect on CAL.
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Using OR Black Box Technology to Determine Quality Improvement Outcomes for In-situ Timeout and Debrief Simulation. Ann. Surg. (IF 7.5) Pub Date : 2024-07-11 Krystle K Campbell, Andres A Abreu, Herbert J Zeh, William C Daniel, Vanessa N Palter, Samantha J Bishop, Suzanne Sims, Jaffer M Odeh, Kim Evans, Priya Dandekar, Daniel J Scott
The purpose of this study was to determine quality improvement outcomes following the pilot implementation of an in-situ simulation designed to enhance surgical safety checklist performance.
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Statistical Methods to Examine Racial and Ethnic Disparities in the Surgical Literature: A Review and Recommendations for Improvement. Ann. Surg. (IF 7.5) Pub Date : 2024-07-09 Alex H S Harris, Hyrum Eddington, Vaibhavi B Shah, Michael Shwartz, Deborah Gurewich, Amy K Rosen, Badí Quinteros, Britni Wilcher, Kenneth J Nieser, Gabrielle Jones, Julie Tsu-Yu Wu, Arden M Morris
We characterized the quality of statistical methods for studies of racial and ethnic disparities in the surgical-relevant literature during 2021-2022.
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Codon-Optimized and de novo-Synthesized E-Selectin/AAV2 Dose-Response Study for Vascular Regeneration Gene Therapy. Ann. Surg. (IF 7.5) Pub Date : 2024-07-08 Francesca A Voza, Barry J Byrne, Yulexi Y Ortiz, Yan Li, Nga Le, Lucy Osafo, Antoine C Ribieras, Hongwei Shao, Carlos Theodore Huerta, Yuntao Wei, Gustavo Falero-Diaz, Andres Franco-Bravo, Roberta M Lassance-Soares, Roberto I Vazquez-Padron, Zhao-Jun Liu, Omaida C Velazquez
This study focuses on dose-response investigation using a codon-optimized and de novo-synthesized E-Selectin/AAV2 (E-Sel/AAV2) vector in preparation for Investigational New Drug (IND)-enabling of subsequent clinical studies.
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Association of Hospital System Affiliation with Spending and Postoperative Outcomes: A Longitudinal Study of Hospital Mergers And Acquisitions From 2010 To 2018. Ann. Surg. (IF 7.5) Pub Date : 2024-07-08 Adrian Diaz, Usha Nuliyalu, Andrew M Ryan, Justin B Dimick, Andrew M Ibrahim, Hari Nathan
To determine whether hospital system affiliation was associated with changes in surgical episode spending or postoperative outcomes.
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Blue Ribbon Committee II: Report of the Subcommittee on Faculty Development and Educational Support. Ann. Surg. (IF 7.5) Pub Date : 2024-07-02 Richard Damewood, Fabrizio Michelassi, M Ashraf Mansour, Moshen Shabahan, Kenneth Sharp, Diana Farmer
The American College of Surgeons, American Board of Surgery, and the American Surgical Association have created a Blue Ribbon Committee II to evaluate the current status of surgical education in the United States. As part of this endeavor, a subcommittee was formed to address issues pertinent to development of surgical faculty as teachers. This entailed multiple discussions among a group of experienced
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Lymph Node Yield is Associated with Improved Overall Survival and Increased Time to Recurrence in Node-Negative Pancreatic Ductal Adenocarcinoma Following Neoadjuvant Therapy. Ann. Surg. (IF 7.5) Pub Date : 2024-07-02 Maximiliano Servin-Rojas, Zhi Ven Fong, Carlos Fernandez-Del Castillo, Gabriella Lionetto, Louisa Bolm, Peter J Fagenholz, Cristina R Ferrone, Dario M Rocha-Castellanos, Keith D Lillemoe, Motaz Qadan
To determine if lymph node yield (LNY) is associated with improved overall survival (OS) and time to recurrence (TTR) in patients with node-negative pancreatic ductal adenocarcinoma (PDAC) treated with neoadjuvant therapy (NAT).
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Key Issues in Surgical Residency Education: Recommendations of the Blue Ribbon II Committee Residency Education Subcommittee. Ann. Surg. (IF 7.5) Pub Date : 2024-07-01 John D Mellinger, Karen Brasel, Eric Elster, Gerald Fried, Daniel A Hashimoto, Benjamin Jarman, Amit R T Joshi, Rachel R Kelz, Brenessa Lindeman, Carla Pugh, Richard Reznick
In September 2022, a summit was convened by the American Board of Surgery (ABS) to discuss competency-based reform in surgical education. A key output of that summit was the recommendation that the prior work of the Blue Ribbon I Committee convened 20 years earlier be revived. With leadership from the American College of Surgeons (ACS) and the American Surgical Association (ASA) , the Blue Ribbon Committee
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Maryland's Global Budget Revenue Payment Model and Shifts in the Surgical Site of Care Among Medicare Beneficiaries. Ann. Surg. (IF 7.5) Pub Date : 2024-07-01 Yu-Li Lin, Bradley Herring, Alexander Melamed, Abbas M Hassan, Laura A Petrillo, Nancy L Keating, Anaeze C Offodile
To assess the association between the Global Budget Revenue (GBR) payment model and shifts to the outpatient setting for surgical procedures among Medicare fee-for-service beneficiaries in Maryland versus control states.
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Infiltration of Common Myeloid Progenitor (CMP) Cells is Associated With Less Aggressive Tumor Biology, Lower Risk of Brain Metastasis, Better Response to Immunotherapy and Higher Patient Survival in Breast Cancer. Ann. Surg. (IF 7.5) Pub Date : 2024-07-01 Masanori Oshi, Rongrong Wu, Thaer Khoury, Shipra Gandhi, Li Yan, Akimitsu Yamada, Takashi Ishikawa, Itaru Endo, Kazuaki Takabe
To investigate the clinical relevance of common myeloid progenitor (CMP) cells in breast tumor microenvironment (TME).
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CA 19-9 Surveillance Detects Recurrences Early and Contributes to Improvement in Survival in Resected Ampullary Cancers: Analysis of 572 cases. Ann. Surg. (IF 7.5) Pub Date : 2024-06-28 Manish S Bhandare, Gurudutt P Varty, Ravi Chandra Reddy Obili, Amit Chopde, Akash Pawar, Krishnaveni Krishnakumar, Subhash Yadav, Vikas Ostwal, Anant Ramaswamy, Prabhat Bhargava, Vikram Chaudhari, Shailesh V Shrikhande
To determine the clinical utility of serum CA 19-9 surveillance for detecting recurrences in resected ampullary carcinomas (ACs).
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Safety of Selective Operative Drainage After Pancreatic Resection: A Retrospective Analysis of 2,607 Patients. Ann. Surg. (IF 7.5) Pub Date : 2024-06-28 Josephine Magnin, Joshua S Jolissaint, Hannah E Fuchs, Kenneth Seier, Mithat Gonen, Ahmad Barekzai, Vinod P Balachandran, Michael I D'Angelica, Jeffrey A Drebin, T Peter Kingham, Kevin Soares, Alice C Wei, William R Jarnagin
To assess whether selective omission of operative drains after pancreaticoduodenectomy (PD) and distal pancreatectomy (DP) is associated with adverse perioperative outcomes.
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Harmonizing Definitions and Perspectives in Extreme Liver Surgery: A Delphi Experts Consensus. Ann. Surg. (IF 7.5) Pub Date : 2024-06-28 Victor Lopez-Lopez, Peter Lodge, Karl Oldhafer, Roberto Hernandez-Alejandro, Nobuhisa Akamatsu, Goro Honda, Antonio Pinna, Deniz Balci, Sanjay Govil, Umberto Cillo, Andrea Schlegel, Silvio Nadalin, Fabrizio Di Benedetto, Johann Pratschke, Luca Aldrighetti, Olivier Soubrane, Olivier Scatton, Go Wakabayashi, Irinel Popescu, Jose Manuel Ramia, Masayuki Ohtsuka, Pål-Dag Line, Roberto Ivan Troisi, Marcel
To propose to our community a common language about extreme liver surgery.
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Impact of Surgeon Workload on Pregnancy Outcomes in Surgical Trainees and Faculty. Ann. Surg. (IF 7.5) Pub Date : 2024-06-28 Talar Tatarian, Brigitte Anderson, Michael J Pucci, Courtney L Devin, Elizabeth Liveright, Danielle Cullen, Renee Tholey, Francesco Palazzo, Maria S Altieri
To investigate the association between workload and pregnancy outcomes among US surgical faculty and trainees.
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Defining Global Benchmarks for Laparoscopic Right Posterior Sectionectomy/H67: An International Multicenter Study. Ann. Surg. (IF 7.5) Pub Date : 2024-06-28 Jianping Zhao, Yuanxiang Lu, Wanguang Zhang, Darren W Chua, Qu Liu, Rong Liu, Johann Pratschke, Francesca Ratti, Giuseppe Zimmitti, Davit L Aghayan, Bjørn Edwin, Tiing-Foong Siow, Olivier Scatton, Paulo Herman, Marco V Marino, Vincenzo Mazzaferro, Adrian K H Chiow, Iswanto Sucandy, Arpad Ivanecz, Sung Hoon Choi, Jae Hoon Lee, Mikel Gastaca, Marco Vivarelli, Felice Giuliante, Andrea Ruzzenente, Chee-Chien
We aimed to establish global benchmark outcomes indicators for L-RPS/H67.
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A Randomized Crossover Trial Evaluating the Impact of Cultural Dexterity Training on Surgical Residents' Knowledge, Cross-Cultural Care, Skills, and Beliefs: The Provider Awareness and Cultural dexterity Training for Surgeons (PACTS) Trial. Ann. Surg. (IF 7.5) Pub Date : 2024-06-26 Douglas S Smink, Gezzer Ortega, Brittany M Dacier, Emil R Petrusa, Yu-Jen Chen, Namra Q Shaikh, Benjamin G Allar, Maria B J Chun, Alexander R Green, Katharine E Caldwell, Rachel B Atkinson, Emma Reidy, Olubode A Olufajo, L D Britt, Molly A Brittain, Jorge Zárate Rodriguez, Sandra M Swoboda, Edward E Cornwell, Kenneth A Lynch, Paul E Wise, David T Harrington, Tara S Kent, John T Mullen, Pamela A Lipsett
This trial examines the impact of the Provider Awareness and Cultural dexterity Toolkit for Surgeons (PACTS) curriculum on surgical residents' knowledge, cross-cultural care, skills, and beliefs.
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Long Term Results of Physician Modified Endografts for the Treatment of Elective, Symptomatic and Ruptured Juxtarenal Abdominal Aortic Aneurysms. Ann. Surg. (IF 7.5) Pub Date : 2024-06-26 Benjamin W Starnes, Sara Zettervall, Allison Larimore, Niten Singh
The objective of this study was to report long term results of an ongoing physician-sponsored, investigational device exemption (IDE) pivotal clinical trial using physician-modified endovascular grafts (PMEGs) for the treatment of patients with juxtarenal aortic aneurysms.
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Early Detection of Ventilator-Associated Pneumonia from Exhaled Breath in ICU Patients. Ann. Surg. (IF 7.5) Pub Date : 2024-06-26 Umer Bakali, Chitvan Killawala, Evelise Monteagudo, Michael D Cobler-Lichter, Luciana Tito, Jessica Delamater, Larisa Shagabayeva, Brianna L Collie, Nicole B Lyons, Emre Dikici, Sapna K Deo, Sylvia Daunert, Carl I Schulman
Evaluate associations between volatile organic compounds (VOCs) in heat and moisture exchange (HME) filters and the presence of ventilator-associated pneumonia (VAP).
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Towards a Standardization of Learning Curve Assessment in Minimally Invasive Liver Surgery. Ann. Surg. (IF 7.5) Pub Date : 2024-06-26 Christoph Kuemmerli, Johannes M A Toti, Fabian Haak, Adrian T Billeter, Felix Nickel, Cristiano Guidetti, Martin Santibanes, Luca Vigano, Joël L Lavanchy, Otto Kollmar, Daniel Seehofer, Mohammed Abu Hilal, Fabrizio Di Benedetto, Pierre-Alain Clavien, Philipp Dutkowski, Beat P Müller, Philip C Müller
The aim was to analyze the learning curves of minimal invasive liver surgery(MILS) and propose a standardized reporting.
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Evolution of Pancreas Transplantation At A Single Institution-50+ Years and 2,500 Transplants. Ann. Surg. (IF 7.5) Pub Date : 2024-06-25 Erik B Finger, Abraham J Matar, Ty B Dunn, Abhinav Humar, Angelika C Gruessner, Rainer W G Gruessner, Karthik Ramanathan, Vanessa Humphreville, Arthur J Matas, David E R Sutherland, Raja Kandaswamy
To describe the evolution of pancreas transplantation, including improved outcomes and factors associated with improved outcomes over the past five decades.
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For the Love of the Game: Calculating the Premium Associated with Academic Surgical Practice. Ann. Surg. (IF 7.5) Pub Date : 2024-06-25 Emily A Grimsley, David O Anderson, Melissa A Kendall, Tyler Zander, Rajavi Parikh, Ronald J Weigel, Paul C Kuo
We sought to determine the premium associated with a career in academic surgery, as measured by compensation normalized to the work relative value unit (wRVU).
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A Dwindling Matter: An Analysis of Medicare Reimbursement for Endocrine Surgery Procedures from 2000-23. Ann. Surg. (IF 7.5) Pub Date : 2024-06-25 Anthony T Saxton, Alberto J Monreal, Michael T Stang, Hadiza S Kazaure, Randall P Scheri
To evaluate Medicare reimbursement trends for endocrine surgeries from 2000-23.
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The Use and Impact of a Decision Support Tool for Appendicitis Treatment. Ann. Surg. (IF 7.5) Pub Date : 2024-06-25 Joshua E Rosen, Sarah E Monsell, Sara C DePaoli, Erin C Fannon, Johnathan E Kohler, Caroline E Reinke, Lillian S Kao, Ryan B Fransman, Jonah J Stulberg, Michael B Shapiro, Deepika Nehra, Pauline K Park, Sabrina E Sanchez, Katherine N Fischkoff, Giana H Davidson, David R Flum
Since introducing new and alternative treatment options may increase decisional conflict, we aimed to describe the use of the decision support tool (DST) and its impact on treatment preference and decisional conflict.
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Less is More: Dissecting Trauma Centers by Procedural Volume. Ann. Surg. (IF 7.5) Pub Date : 2024-06-21 Louis J Magnotti, Sai Krishna Bhogadi, Tanya Anand, Collin Stewart, Christina Colosimo, Audrey L Spencer, Adam Nelson, Bellal Joseph
This study aims to examine the relationship between procedural volume and annual trauma volume (ATV) of ACS Level I trauma centers (TC).
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Preoperative Surgical or Endoscopic Bile Duct Drainage in Pancreatic Cancer. Ann. Surg. (IF 7.5) Pub Date : 2024-06-21 Rosa Klotz, Thomas Hank, Miklos P Berente, Maximilian Joos, Ulf Hinz, Frank Pianka, Benedict Kinny-Köster, Mohammed Al-Saeedi, Oliver Strobel, Thilo Hackert, Martin Schneider, Beat Müller-Stich, Christoph Berchtold, Arianeb Mehrabi, Martin Loos, Markus W Büchler
Patients with pancreatic cancer and obstructive jaundice routinely undergo endoscopic stent placement (ES). It is well known that ES causes bacterial contamination and infectious complications after pancreatic resection.
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The Prognostic Impact of Minimally Invasive Esophagectomy on Survival after Esophagectomy following a Delayed Interval after Chemoradiotherapy; A Secondary Analysis of the DICE Study. Ann. Surg. (IF 7.5) Pub Date : 2024-06-21 Sheraz R Markar, Bruno Sgromo, Richard Evans, Ewen A Griffiths, Rita Alfieri, Carlo Castoro, Caroline Gronnier, Christian A Gutschow, Guillaume Piessen, Giovanni Capovilla, Peter P Grimminger, Donald E Low, James Gossage, Suzanne S Gisbertz, Jelle Ruurda, Richard van Hillegersberg, Xavier Benoit D'journo, Alexander W Phillips, Ricardo Rosati, George B Hanna, Nick Maynard, Wayne Hofstetter, Lorenzo
To evaluate prognostic differences between minimally invasive esophagectomy (MIE) and open esophagectomy (OE) in patients with surgery after a prolonged interval (>12 wk) following chemoradiotherapy (CRT).
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Pelvic Floor Rehabilitation After Rectal Cancer Surgery One-year follow-up of a Multicenter Randomized Clinical Trial (FORCE trial). Ann. Surg. (IF 7.5) Pub Date : 2024-06-20 N M Bosch, A J Kalkdijk-Dijkstra, H L van Westreenen, Pma Broens, Jpen Pierie, Jag van der Heijden, B R Klarenbeek
This study aims to evaluate the effects of pelvic floor rehabilitation (PFR) after low anterior resection (LAR) at one-year follow-up.
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Tumor-intrinsic and Cancer-associated Fibroblast Subtypes Independently Predict Outcomes in Pancreatic Cancer. Ann. Surg. (IF 7.5) Pub Date : 2024-06-18 Jaewon J Lee, Joseph F Kearney, Hannah E Trembath, Arthi Hariharan, Michelle E LaBella, Elena V Kharitonova, Priscilla S Chan, Ashley B Morrison, Ashley Cliff, Michael O Meyers, Hong Jin Kim, Naim U Rashid, Xianlu L Peng, Jen Jen Yeh
To assess the utility of tumor-intrinsic and cancer-associated fibroblast (CAF) subtypes of pancreatic ductal adenocarcinoma (PDAC) in predicting response to neoadjuvant therapy (NAT) and overall survival.
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Right Ex-situ split grafts for adult liver transplantation - A Multicenter Benchmarking Analysis. Ann. Surg. (IF 7.5) Pub Date : 2024-06-18 Natacha Boulanger, Xavier Muller, Federica Dondero, Nicolas Golse, Claire Goumard, Antoine Breton, Ailton Sepulveda, Marc-Antoine Allard, Eric Savier, Safi Dokmak, Gabriella Pittau, Oriana Ciacio, Chady Salloum, Fabiano Perdigão, Géraldine Rousseau, Chetana Lim, Guillaume Rossignol, Eric Vibert, Antonio Sa Cunha, Kayvan Mohkam, Daniel Azoulay, René Adam, Olivier Scatton, Mickael Lesurtel, Daniel Cherqui
To analyse outcomes after adult right ex-situ split graft liver transplantations (RSLT) and compare with available outcome benchmarks from whole liver transplantation (WLT).
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An Analysis of Water Used and Wasted at Operating Room (OR) Scrub Sinks and Call to Action for Reducing Water Waste. Ann. Surg. (IF 7.5) Pub Date : 2024-06-18 Carolyn J Hu, Margaret Reilly, Imadh Khan, Andrew W Hoel, Cord Sturgeon, Karen J Ho
To model the volume of water used and wasted during wet scrubs at operating room (OR) scrub sinks and identify factors for reducing water waste.
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A Contemporary Evaluation of the Centers for Medicare and Medicaid Services High-Risk Indicators for Carotid Endarterectomy. Ann. Surg. (IF 7.5) Pub Date : 2024-06-18 Sabrina Straus, Batol Barodi, Sina Zarrintan, Daniel Willie-Permor, Nishita Vootukuru, Mahmoud Malas
Compare stroke/death outcomes across Carotid Endarterectomy (CEA), Transcarotid Artery Revascularization (TCAR), and Transfemoral Carotid Artery Stenting (TFCAS) using Centers for Medicare & Medicaid Services (CMS) high-risk criterion.
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Entrustable Professional Activities in Postgraduate General Surgery Training: A Scoping Review. Ann. Surg. (IF 7.5) Pub Date : 2024-06-17 Daniel Nel, Eduard Jonas, Vanessa Burch, Lydia Cairncross, Amy Nel, Adnan Alseidi, Brian George, Olle Ten Cate
To provide an overview of the current use of Entrustable Professional Activities (EPAs) in postgraduate general surgery training internationally.
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Circulating microRNA as a Potential Biomarker for Skeletal Disease in Primary Hyperparathyroidism: A Case-control Study. Ann. Surg. (IF 7.5) Pub Date : 2024-06-17 Heather Wachtel, Jae P Ermer, Douglas L Fraker, Rachel R Kelz, Thomas L A Kelly, Matthias Hackl, Michael A Levine
The goal of this study was to characterize the microRNA (miRNA) expression signatures in patients with PHPT and identify miRNA biomarkers of bone homeostasis.
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Local Management for Diabetic Foot Ulcers: A Systematic Review and Network Meta-analysis of Randomized Controlled Trials. Ann. Surg. (IF 7.5) Pub Date : 2024-06-17 Hu Qian, Yang Jian, Xiangyuan Chu, Yuanliang Wang, Zhu Liu, Neng Zhang, Chenliang Deng, Xiuquan Shi, Zairong Wei
This study evaluated the efficacy of various local management strategies for diabetic foot ulcers (DFUs).
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Decoding the Clavien-Dindo Classification: Artificial Intelligence (AI) as a Novel Tool to Grade Postoperative Complications. Ann. Surg. (IF 7.5) Pub Date : 2024-06-17 Sebastian Manuel Staubli, Harriet Louise Walker, Fuat Saner, Camila Hidalgo Salinas, Dieter C Broering, Massimo Malagò, Michael Spiro, Dimitri Aristotle Raptis
To assess ChatGPT's capability of grading postoperative complications using the Clavien-Dindo classification (CDC) via Artificial Intelligence (AI) with Natural Language Processing (NLP).
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Surgical Antimicrobial Prophylaxis in Low-Risk Cholecystectomies is Associated with Fewer Surgical Site Infections: Nationwide Cohort Study in Switzerland. Ann. Surg. (IF 7.5) Pub Date : 2024-06-17 Lena Florinett, Andreas Widmer, Nicolas Troillet, Guido Beldi, Markus Von Flüe, Stephan Harbarth, Rami Sommerstein
To assess whether administration of surgical antimicrobial prophylaxis (SAP) versus absence of SAP is associated with a decreased risk of surgical site infections (SSI) after low-risk cholecystectomies (LR-CCE).
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Benefits of Aerosolized, Point-of-care, Autologous Skin Cell Suspension (ASCS) for the Closure of full Thickness Wounds from Thermal and Non-Thermal Causes: Learning Curves from the first 50 Consecutive cases at an Urban, Level 1 Trauma Center. Ann. Surg. (IF 7.5) Pub Date : 2024-06-13 C Scott Hultman, Ursula C Adams, Corianne D Rogers, Minakshi Pillai, Samantha T Brown, Carrie Ann McGroarty, Michelle McMoon, M Georgina Uberti
To determine the utility of Autologous Skin Cell Suspension (ASCS) in closing full-thickness (FT) defects from injury and infection.
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Functional Outcomes After Transanal Total Mesorectal Excision (taTME) for Rectal Cancer: Results from the Phase II North American Multicenter Prospective Observational Trial. Ann. Surg. (IF 7.5) Pub Date : 2024-06-13 Katherine F Donovan, Katherine C Lee, Alison Ricardo, Natalie Berger, Antoinette Bonaccorso, Karim Alavi, Karen Zaghiyan, Alessio Pigazzi, Dana Sands, Teresa DeBeche-Adams, Sami A Chadi, Elisabeth C McLemore, John H Marks, Justin A Maykel, Sherief F Shawki, Scott R Steele, Matthew Albert, Mark Whiteford, Fu-Yuan Cheng, Steven D Wexner, Patricia Sylla
To investigate fecal incontinence and defecatory, urinary, and sexual functional outcomes after taTME.
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Can Lymph Node Involvement in Unilateral Wilms Tumor be Predicted by Preoperatively known Data in Combination with Intraoperative Findings? Ann. Surg. (IF 7.5) Pub Date : 2024-06-12 Clemens-Magnus Meier, Rhoikos Furtwängler, Nils Welter, Marvin Mergen, Stefan Wagenpfeil, Dietrich von Schweinitz, Raimund Stein, Leo Kager, Jens-Peter Schenk, Christian Vokuhl, Sabine Kroiss-Benninger, Patrick Melchior, Steven W Warmann, Jörg Fuchs, Norbert Graf
This study aimed to identify parameters that allow the estimation of tumor-infiltrated lymph nodes (LN) after pretreatment for unilateral Wilms tumor (WT).
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Persistence and Sexual Dimorphism of Gut Dysbiosis and Pathobiome after Sepsis and Trauma. Ann. Surg. (IF 7.5) Pub Date : 2024-06-12 Jennifer A Munley, Gwoncheol Park, Lauren S Kelly, Kolenkode B Kannan, Robert T Mankowski, Gemma Casadesus, Paramita Chakrabarty, Shannon M Wallet, Robert Maile, Letitia E Bible, Bo Wang, Lyle L Moldawer, Alicia M Mohr, Ravinder Nagpal, Philip A Efron
To evaluate the persistence of intestinal microbiome dysbiosis and gut-plasma metabolomic perturbations following severe trauma or sepsis weeks after admission in patients experiencing chronic critical illness (CCI).
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Traumatic Thoracic Aortic Coarctation after Blunt Thoracic Aortic Injury Mandates Emergent Thoracic Endovascular Aortic Repair. Ann. Surg. (IF 7.5) Pub Date : 2024-06-12 Maunil N Bhatt, Saskya Byerly, Dina M Filiberto, Muhammad O Afzal, Timothy C Fabian, Martin A Croce, Erica L Mitchell
This study sought to elucidate clinical and imaging findings predictive for malperfusion syndrome after blunt thoracic aortic injury (BTAI).
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Extended Pharmacologic Prophylaxis for Venous Thromboembolism after Colon Cancer Surgery is Associated with Improved Long-term Survival: A Natural Experiment in the Chemotherapeutic Benefit of Heparin Derivatives. Ann. Surg. (IF 7.5) Pub Date : 2024-06-11 Alexander Booth, Daniel Brinton, Colleen Donahue, Maggie Westfal, Virgilio George, Pinckney J Maxwell, Kit Simpson, David Mahvi, Thomas Curran
This large database study assessed whether extended pharmacologic prophylaxis for venous thromboembolism after colon cancer resection was associated with improved oncologic survival.
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Association between Complications and Death within 30 days after General Surgery: A Vascular Events in Noncardiac Surgery Patients Cohort Evaluation (VISION) substudy. Ann. Surg. (IF 7.5) Pub Date : 2024-06-11 Lily J Park, Flavia K Borges, Sandra Ofori, Rahima Nenshi, Michael Jacka, Diane Heels-Ansdell, Jessica Bogach, Kelly Vogt, Matthew Tv Chan, Anish Verghese, Carisi A Polanczyk, David Skinner, J M Asencio, Pilar Paniagua, Michael Rosen, Pablo E Serrano, Michael J Marcaccio, Marko Simunovic, Lehana Thabane, P J Devereaux
To determine the epidemiology of post-operative complications among general surgery patients, inform their relationships with 30-day mortality, and determine the attributable fraction of death of each postoperative complication.
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Optimal Timing for Initiation of Thromboprophylaxis After Hepatic Angioembolization. Ann. Surg. (IF 7.5) Pub Date : 2024-06-11 Brianna L Collie, Nicole B Lyons, Logan Goddard, Michael D Cobler-Lichter, Jessica M Delamater, Larisa Shagabayeva, Edward B Lineen, Carl I Schulman, Kenneth G Proctor, Jonathan P Meizoso, Nicholas Namias, Enrique Ginzburg
To evaluate the optimal timing of thromboprophylaxis (TPX) initiation after hepatic angioembolization in trauma patients.
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Renoprotective Effects of Metabolic Surgery Versus GLP1 Receptor Agonists on Progression of Kidney Impairment in Patients with Established Kidney Disease. Ann. Surg. (IF 7.5) Pub Date : 2024-06-11 Ali Aminian, Hamlet Gasoyan, Alexander Zajichek, Mohammad Hesam Alavi, Nicholas J Casacchia, Rickesha Wilson, Xiaoxi Feng, Ricard Corcelles, Stacy A Brethauer, Philip R Schauer, Matthew Kroh, Raul J Rosenthal, Jonathan J Taliercio, Emilio D Poggio, Steven E Nissen, Michael B Rothberg
To examine the renoprotective effects of metabolic surgery in patients with established chronic kidney disease (CKD).
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Adding Patient-Reported Outcomes to the American College of Surgeons National Surgical Quality Improvement Program: Results of the First 33,842 Patients from 65 Hospitals. Ann. Surg. (IF 7.5) Pub Date : 2024-06-11 Jason B Liu, Andrea L Pusic, Alexa D Melucci, Brian C Brajcich, Matthew Fordham, Jakob C Lapsley, Clifford Y Ko, Larissa K Temple
To investigate the initial set of patient-reported outcomes (PROs) in the ACS NSQIP and their associations with 30-day surgical outcomes.
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The Impact of Sex on Antiplatelet and Anticoagulant Thromboprophylaxis in Patients with Peripheral Artery Disease Post-revascularization. Ann. Surg. (IF 7.5) Pub Date : 2024-06-11 Sasha Suarez, Aniket Agrawal, Shiv Patel, Benjamin Grobman, Samir Ghandour, Leela Morena, Adriana Rodriguez, Kellie Machlus, Trisha Roy, Matthew Eagleton, Anahita Dua
The aim of this prospective study was to 1) objectively quantify the impact of sex on platelet function in patients with PAD taking antiplatelet and anticoagulant medications and 2) to develop and test a personalized, iterative algorithm which personalizes thromboprophylaxis that incorporates platelet function testing.
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Postoperative Outcomes Among Patients Undergoing Cancer Surgery: United States versus International Medical Graduates. Ann. Surg. (IF 7.5) Pub Date : 2024-06-11 Muhammad Muntazir Mehdi Khan, Muhammad Musaab Munir, Selamawit Woldesenbet, Mujtaba Khalil, Yutaka Endo, Erryk Katayama, Diamantis Tsilimigras, Zayed Rashid, Abdullah Altaf, Mary Dillhoff, Susan Tsai, Timothy M Pawlik
We sought to characterize postoperative outcomes among patients who underwent an oncologic operation relative to whether the treating surgeon was an international medical graduate (IMG) versus a United States medical graduate (USMG).
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Tumor Mutational Burden from Circulating Tumor DNA Predicts Recurrence of Hepatocellular Carcinoma After Resection: An Emerging Biomarker for Surveillance: An Emerging Biomarker for Surveillance. Ann. Surg. (IF 7.5) Pub Date : 2024-06-11 Chase J Wehrle, Hanna Hong, Suneel Kamath, Andrea Schlegel, Masato Fujiki, Koji Hashimoto, David Choon Hyuck Kwon, Charles Miller, R Matthew Walsh, Federico Aucejo
Describe the utility of circulating tumor DNA in the post-operative surveillance of hepatocellular carcinoma (HCC).
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Objective Assessment of Cognitive Workload in Surgery: A Systematic Review. Ann. Surg. (IF 7.5) Pub Date : 2024-06-07 Aws Almukhtar, Virginia Caddick, Ravi Naik, Mary Goble, George Mylonas, Ara Darzi, Felipe Orihuela-Espina, Daniel R Leff
To systematically review technologies that objectively measure CWL in surgery, assessing their psychometric and methodological characteristics.
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Surgical Intelligence can Lead to Higher Adoption of Best Practices in Minimally Invasive Surgery. Ann. Surg. (IF 7.5) Pub Date : 2024-06-06 Gerald M Fried, Monica Ortenzi, Danit Dayan, Eran Nizri, Yuval Mirkin, Sari Maril, Dotan Asselmann, Tamir Wolf
To examine the use of surgical intelligence for automatically monitoring critical view of safety (CVS) in laparoscopic cholecystectomy (LC) in a real-world quality initiative.
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Genetically Modified Porcine Kidneys Have Sufficient Tissue Integrity for Use in Pig-to-Human Xenotransplantation. Ann. Surg. (IF 7.5) Pub Date : 2024-06-06 Douglas J Anderson, Maggie Jones-Carr, Jackson Perry, Vineeta Kumar, Paige Porrett, Jayme E Locke
We sought to determine if genetically modified porcine kidneys used for xenotransplantation had sufficient tissue integrity to support long term function in a human recipient.
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Consequences of a Surveillance Strategy for Side-Branch Intraductal Pancreatic Mucinous Neoplasms: Long-Term Follow-Up of One-Thousand Cysts. Ann. Surg. (IF 7.5) Pub Date : 2024-06-06 Chase J Wehrle, Mir Shanaz Hossain, Breanna Perlmutter, Jenny H Chang, Daniel Joyce, Robert Simon, Toms Augustin, R Matthew Walsh
We aim to quantify the rate of progression in surveilled cysts and assess what factors should indicate delayed resection.
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Infrapopliteal Endovascular Interventions for Claudication Are Associated with Poor Long-Term Outcomes in Medicare-Matched Registry Patients. Ann. Surg. (IF 7.5) Pub Date : 2024-06-06 Sanuja Bose, Katherine M McDermott, Chen Dun, Jialin Mao, Alex J Solomon, James H Black, Jesse A Columbo, Michael S Conte, Sarah E Deery, Philip P Goodney, Rohan Kalathiya, Corey A Kalbaugh, Jeffrey J Siracuse, Karen Woo, Martin A Makary, Caitlin W Hicks
There are limited data supporting or opposing the use of infrapopliteal peripheral vascular interventions (PVI) for the treatment of claudication.
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Graft Inflow Modulation by Splenic Artery Ligation for Portal Hyper Perfusion does not Decrease Rates of Early Allograft Dysfunction in Adult Live Donor Liver Transplantation: A Randomized Control Trial. Ann. Surg. (IF 7.5) Pub Date : 2024-06-06 Viniyendra Pamecha, Gattu Tharun, Nilesh Patil, Nihar Mohapatra, Anubhav Kumar, Shalini Thapar, Gaurav Sindwani, Udit Dhingra, Anil Yadav
The primary objective was to compare the rates of early allograft dysfunction (EAD) in patients undergoing elective adult live donor liver transplantation (ALDLT) with and without graft portal inflow modulation (GIM) for portal hyper-perfusion. The secondary objectives were to compare time to normalization of bilirubin and International Normalized Ratio (INR), day 14 ascitic output more than 1liter
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Genomic Landscape of Adenocarcinomas Across the Gastroesophageal Junction: Moving on from the Siewert Classification. Ann. Surg. (IF 7.5) Pub Date : 2024-06-06 Masaya Nakauchi, Henry S Walch, Samuel Nussenzweig, Rebecca Carr, Elvira Vos, Michael F Berger, Nikolaus Schultz, Yelena Janjigian, Abraham Wu, Laura Tang, Pari Shah, David R Jones, Dan Coit, Vivian E Strong, Daniela Molena, Smita Sihag
To investigate how the Siewert classification of gastroesophageal junction adenocarcinomas correlates with genomic profiles.