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Enhanced CRISPR-Cas9 RNA system delivery using cell penetrating peptides-based nanoparticles for efficient in vitro and in vivo applications J. Control. Release (IF 10.5) Pub Date : 2024-11-11 Veronica Guzman Gonzalez, Audrey Grunenberger, Olivier Nicoud, Elodie Czuba, Julien Vollaire, Véronique Josserand, Xavier Le Guével, Nail Desai, Jean-Luc Coll, Gilles Divita, Virginie Faure
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Ultrasound-activated microbubbles mediate F-actin disruptions and endothelial gap formation during sonoporation J. Control. Release (IF 10.5) Pub Date : 2024-11-12 Bram Meijlink, H. Rhodé van der Kooij, Yuchen Wang, Hongchen Li, Stephan Huveneers, Klazina Kooiman
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Understanding vaginal biofilms: The first step in harnessing antimicrobial nanomedicine J. Control. Release (IF 10.5) Pub Date : 2024-11-12 Sybil Obuobi, Nataša Škalko-Basnet
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Injectable nanocomposite hydrogel with cascade drug release for treatment of uveal melanoma J. Control. Release (IF 10.5) Pub Date : 2024-11-09 Zhihao Guo, Linyun Xiu, Yumei Li, Jiangcheng Tan, Cailing Wei, Junhui Sui, Shijin Zhang, Ruohua Zhu, Ji-Liang Li
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Engineering of phosphatidylserine-targeting ROS-responsive polymeric prodrug for the repair of ischemia-reperfusion-induced acute kidney injury J. Control. Release (IF 10.5) Pub Date : 2024-11-09 Jin-Hui Wang, Hai-Bo Mao, Jing-Bo Hu, Shunhua Cheng, Hao Su
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Engineered manganese-BODIPY coordinated nanoadjuvants for enhanced NIR-II photo-metalloimmunotherapy J. Control. Release (IF 10.5) Pub Date : 2024-11-09 Yushi Zhang, Xuya Yu, Lingpeng Luo, Yigang Xu, Hanjie Zhang, Zhuo Mao, Yuqin Zhang, Cuihong Yang, Lu Wang, Pengcheng Zhang, Sitong Li, Meitong Ou, Ran Luo, Dunwan Zhu, Wen Li, Lin Mei
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Lipidation-dimerization platform unlocks treatment potential of fibroblast growth factor 21 for non-alcoholic steatohepatitis J. Control. Release (IF 10.5) Pub Date : 2024-11-09 Yapeng Wang, Lei Shen, Chengcheng Wang, Yuanzhen Dong, Haoju Hua, Jun Xu, Ying Zhang, Hao Huang, Zongqing Huang, Fei Zhao, Zhiru Xu, Yunliang Qiu, Jianguang Lu, Dianwen Ju, Jun Feng
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Fluorinated dendrimer-mediated miR-30a delivery regulates the inflammation of macrophages and mitigates the symptoms of rheumatoid arthritis J. Control. Release (IF 10.5) Pub Date : 2024-11-09 Jiakai Xing, Jiaxin Jia, Hugang Zhang, Haobo Han, Quanshun Li
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Cerebral biomimetic nano-drug delivery systems: A frontier strategy for immunotherapy J. Control. Release (IF 10.5) Pub Date : 2024-11-08 Hao Tian, Jiaxin Yao, Qi Ba, Yuanyuan Meng, Yanan Cui, Liangzhu Quan, Wei Gong, Yuli Wang, Yang Yang, Meiyan Yang, Chunsheng Gao
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Controlled release of mesenchymal stem cell-derived nanovesicles through glucose- and reactive oxygen species-responsive hydrogels accelerates diabetic wound healing J. Control. Release (IF 10.5) Pub Date : 2024-11-07 Fangzhou Du, Shumang Zhang, Shikai Li, Shaocong Zhou, Dongao Zeng, Jingzhong Zhang, Shuang Yu
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Reactive oxygen species-responsive polydopamine-PtCuTe nanoparticle-loaded microneedle system for promoting the healing of infected skin wounds J. Control. Release (IF 10.5) Pub Date : 2024-11-07 Hongfan Che, Junzhi Xu, Dong Wu, Siliang Chen, Chengkang Liu, Chongbao Zhao, Kun Peng
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Leveraging machine learning to streamline the development of liposomal drug delivery systems J. Control. Release (IF 10.5) Pub Date : 2024-11-08 Remo Eugster, Markus Orsi, Giorgio Buttitta, Nicola Serafini, Mattia Tiboni, Luca Casettari, Jean-Louis Reymond, Simone Aleandri, Paola Luciani
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Combination of multivalent DR5 receptor clustering agonists and histone deacetylase inhibitors for treatment of colon cancer J. Control. Release (IF 10.5) Pub Date : 2024-11-08 Jiahui Li, Jaden Arnold, Monika Sima, Hasan Al Faruque, Jacob Galang, Sophia Hu-Lieskovan, Jindřich Kopeček, Jiyuan Yang
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Advancing osteosarcoma 3D modeling in vitro for novel tumor microenvironment-targeted therapies development J. Control. Release (IF 10.5) Pub Date : 2024-11-08 Sofia Costa, João Rodrigues, Carolina Vieira, Sofia Dias, Juliana Viegas, Flávia Castro, Bruno Sarmento, Catarina Leite Pereira
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Surface-engineered mesenchymal stem cell for refractory asthma therapy: Reversing airway remodeling J. Control. Release (IF 10.5) Pub Date : 2024-11-06 Xing-Yue He, Meng-Meng Han, Yu-Chen Zhao, Ling Tang, Yi Wang, Lei Xing, Ning Wei, Jing Wang, Guang-Ji Wang, Fang Zhou, Jee-Heon Jeong, Hu-Lin Jiang
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Corrigendum to “Bacteria-mimetic nanomedicine for targeted eradication of intracellular MRSA” [Journal of Controlled Release 357 (2023) 371–378] J. Control. Release (IF 10.5) Pub Date : 2024-11-06 Beibei Xie, Huichao Zhao, Ruixue Zhang, Yuanfu Ding, Cheng Gao, Yun He, Ruibing Wang
The authors regret that the tissue sections for histological examination (HE staining) related to Fig. 5a were inadvertently mixed among several different groups from two concurrent projects by the first author, resulting in the misplacements of multiple HE staining images in this figure. This oversight was recently discovered by the first author himself. To ensure that the correct tissue sections
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Conquering dual challenges: A sialic-modified liposome for targeting activated neutrophils to tackle comorbid lung inflammation and cancer metastasis J. Control. Release (IF 10.5) Pub Date : 2024-11-06 Cong Li, Zhihang Li, Lihong Wang, Kexin Zhang, Zehao Li, Yating Ji, Jing Li, Yifan Zhang, Lijiang Chen
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Phage-liposome nanoconjugates for orthopedic biofilm eradication J. Control. Release (IF 10.5) Pub Date : 2024-11-06 Lei Wang, Tamta Tkhilaishvili, Zheng Jiang, Rima Fanaei Pirlar, Yu Ning, Adrián Millán Laleona, Jiaxing Wang, Jin Tang, Qiaojie Wang, Andrej Trampuz, Mercedes Gonzalez Moreno, Xianlong Zhang
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A reactive oxygen species-triggerable theranostic prodrug system J. Control. Release (IF 10.5) Pub Date : 2024-11-06 Feiyang Liu, Lingyan Liu, Peng Wei, Tao Yi
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Microparticle and nanoparticle-based influenza vaccines J. Control. Release (IF 10.5) Pub Date : 2024-11-06 Luis Ontiveros-Padilla, Eric M. Bachelder, Kristy M. Ainslie
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Spatiotemporally cascade-driven “Lipomicelles” enhance extracellular matrix penetration and remodel intercellular crosstalk in pulmonary fibrosis J. Control. Release (IF 10.5) Pub Date : 2024-11-05 Xin Chang, Yu-Mo Han, Qiu-Ling Li, Chao Wang, Bin Guo, Hu-Lin Jiang
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Copper peroxide-decorated Prussian blue for effective bacterial elimination via photothermal-enhanced and H2O2-releasing chemodynamic therapy J. Control. Release (IF 10.5) Pub Date : 2024-11-06 Guitao Tan, Chenyang Qi, Qinqin Zhang, Haonan Hu, Bingtian Tu, Jing Tu
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Anti-CTLA-4 antibody self-presented dendritic cell nanovesicles boost the immunotherapy of hepatocellular carcinoma after microwave ablation J. Control. Release (IF 10.5) Pub Date : 2024-11-06 Tan Li, Bo Li, Liteng Lin, Gengjia Chen, Xiaobin Wang, Ye Chen, Wensou Huang, Mingyue Cai, Xintao Shuai, Kangshun Zhu
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Synthesis and mechanism of Mg/Al layered double oxides-silica nanocomposites for sustainable multi-nutrient delivery in agricultural applications J. Control. Release (IF 10.5) Pub Date : 2024-11-05 Aihua Xiang, Yifan Li, Tuanliu Hu, Kun Liu
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Macropinocytosis-targeted peptide-docetaxel conjugate for bystander pancreatic cancer treatment J. Control. Release (IF 10.5) Pub Date : 2024-11-05 Young Seok Cho, Hanhee Cho, Ha Rin Kim, Seong Jin Park, Joo Hye Yeo, Yoon Gun Ko, Jinu Lee, Sang Yoon Kim, Kwangmeyung Kim, Youngro Byun
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Multifunctional nanoparticles potentiate in-situ tumor vaccines via reversing insufficient Photothermal therapy by disrupting tumor vasculature J. Control. Release (IF 10.5) Pub Date : 2024-11-05 Lili Zhao, Yiran Liu, Fangfei Jin, Kaiyuan Hu, Miao Lv, Yuehua Zhou, Weijun Zhao, Yiqiao Hu, Jinhui Wu, Yong Yang, Wenguang Wang
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Local drug delivery challenges and innovations in spinal neurosurgery. J. Control. Release (IF 10.5) Pub Date : 2024-11-04 Christina Karavasili,Thomas Young,Joshua Francis,Julianna Blanco,Nicholas Mancini,Charmaine Chang,Joshua D Bernstock,Ian Connolly,Ganesh Shankar,Giovanni Traverso
The development of novel therapeutics in the field of spinal neurosurgery faces a litany of translational challenges. Achieving precise drug targeting within the confined spaces associated with the spinal cord, canal and vertebra requires the development of next generation delivery systems and devices. These must be capable of overcoming inherent barriers related to drug diffusion, whilst concurrently
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Next-generation 3D printed multipurpose prevention intravaginal ring for prevention of HIV, HSV-2, and unintended pregnancy. J. Control. Release (IF 10.5) Pub Date : 2024-11-03 Denali K Dahl,Priya Srinivasan,Rima Janusziewicz,Jasmine L King,Roopali Shrivastava,Jining Zhang,Dawn Little,Shanon Bachman,Kristen Kelley,Mackenzie L Cottrell,Amanda P Schauer,Craig Sykes,Angela D M Kashuba,James Smith,S Rahima Benhabbour
Globally, nearly half of all pregnancies are unintended, ~1.3 million new human immunodeficiency virus (HIV) infections are reported every year, and more than 500 million people are estimated to have a genital herpes simplex virus (HSV-2) infection. Here we report the first 3D printed multipurpose prevention technology (MPT) intravaginal ring (IVR) for prevention of HIV, HSV-2, and unintended pregnancy
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Tissue nano-transfection of antimicrobial genes drives bacterial biofilm killing in wounds and is potentially mediated by extracellular vesicles. J. Control. Release (IF 10.5) Pub Date : 2024-11-02 Tatiana Z Cuellar-Gaviria,Maria Angelica Rincon-Benavides,Hatice Nur Halipci Topsakal,Ana Isabel Salazar-Puerta,Shara Jaramillo-Garrido,Mia Kordowski,Carlos A Vasquez-Martinez,Kim Truc Nguyen,Xilal Y Rima,Pranav S J B Rana,Orlando Combita-Heredia,Binbin Deng,Kavya Dathathreya,David W McComb,Eduardo Reategui,Daniel Wozniak,Natalia Higuita-Castro,Daniel Gallego-Perez
The emergence of bacteria that are resistant to antibiotics is on track to become a major global health crisis. Therefore, there is an urgent need for new treatment options. Here, we studied the implementation of tissue-nanotransfection (TNT) to treat Staphylococcus aureus-infected wounds by delivering gene cargos that boost the levels of naturally produced antimicrobial peptides. The Cathelicidin
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Extracellular vesicles powered cancer immunotherapy: Targeted delivery of adenovirus-based cancer vaccine in humanized melanoma model J. Control. Release (IF 10.5) Pub Date : 2024-11-01 Sara Mathlouthi, Lukasz Kuryk, Marta Prygiel, Maria Giovanna Lupo, Aleksandra Anna Zasada, Cristiano Pesce, Nicola Ferri, Beate Rinner, Stefano Salmaso, Mariangela Garofalo
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Oxygen self-supplying nanoradiosensitizer activates cGAS-STING pathway to enhance radioimmunotherapy of triple negative breast cancer J. Control. Release (IF 10.5) Pub Date : 2024-11-01 Xiaofei Wang, Yang Yang, Peng Wang, Qingdong Li, Wenjuan Gao, Yu Sun, Geng Tian, Guilong Zhang, Jianmin Xiao
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Targeted NAD+ repletion via biomimetic nanoparticle enables simultaneous management of intimal hyperplasia and accelerated re-endothelialization: A proof-of-concept study toward next-generation of endothelium-protective, anti-restenotic therapy J. Control. Release (IF 10.5) Pub Date : 2024-11-01 Li Yin, Yao Tong, Ruosen Xie, Zhanpeng Zhang, Zain Husain Islam, Kaijie Zhang, Jacobus Burger, Nicholas Hoyt, Eric William Kent, William Aaron Marcum, Campbell Johnston, Rohan Kanchetty, Zoe Tetz, Sophia Stanisic, Yitao Huang, Lian-Wang Guo, Shaoqin Gong, Bowen Wang
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Immunomodulatory microneedle patch for enhanced Ferroptosis and immunogenic cell death in postoperative tumor therapy J. Control. Release (IF 10.5) Pub Date : 2024-10-31 Yuqin Wang, Quanmin Wang, Qingguo Zhong, Yanteng Xu, Chunxiong Zheng, Mingqiang Li, Yu Tao, Enguo Ju
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Targeted delivery of rapamycin and inhibition of platelet adhesion with multifunctional peptide nanoparticles for atherosclerosis treatment J. Control. Release (IF 10.5) Pub Date : 2024-10-31 Anqi Wang, Kai Yue, Weishen Zhong, Genpei Zhang, Xinxin Zhang, Lei Wang
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A bifunctional nanocomplex with remineralizing and antibacterial activities to interrupt dental caries J. Control. Release (IF 10.5) Pub Date : 2024-10-30 Cheng Zhi, Xu Chen, Kaining Yu, Min Li, Fan Li, Yangyang Ye, Yanyun Pang, Ye Zhang, Xiangyu Zhang, Xu Zhang
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A single molecule carrier for ocular posterior segment diseases J. Control. Release (IF 10.5) Pub Date : 2024-10-29 Xiao-Ling Zhang, Yu-Xin Yue, Yang Yang, An-Kang Ying, Rong Ma, Jie Chen, Fang-Yuan Chen, Xiao-Yun Hou, Yu-Chen Pan, Da-Zhuang Ren, Tao Yang, Zhi-Qing Li, Dong-Sheng Guo
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Recent advances in liposomes and peptide-based therapeutics for glioblastoma treatment J. Control. Release (IF 10.5) Pub Date : 2024-10-30 M.-A. Jourdain, J. Eyer
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Drug conjugates crosslinked bioresponsive hydrogel for combination therapy of diabetic wound J. Control. Release (IF 10.5) Pub Date : 2024-10-30 Manhui Zheng, Wenxiang Song, Peipei Huang, Yueping Huang, Hanxuan Lin, Miao Zhang, Huacheng He, Jiang Wu
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A pH and glutathione-responsive carbon monoxide-driven nano-herb delivery system for enhanced immunotherapy in colorectal cancer J. Control. Release (IF 10.5) Pub Date : 2024-10-25 Chen Yang, Hui Ming, Bowen Li, Shanshan Liu, Lihua Chen, Tingting Zhang, Yajie Gao, Tao He, Canhua Huang, Zhongyan Du
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Optimizing lipid nanoparticles for fetal gene delivery in vitro, ex vivo, and aided with machine learning J. Control. Release (IF 10.5) Pub Date : 2024-10-28 Amr Abostait, Mahmoud Abdelkarim, Zeqing Bao, Yuichiro Miyake, Wai Hei Tse, Caterina Di Ciano-Oliveir, Tina Buerki-Thurnherr, Christine Allen, Richard Keijzer, Hagar I. Labouta
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Tumor therapy utilizing dual-responsive nanoparticles: A multifaceted approach integrating calcium-overload and PTT/CDT/chemotherapy J. Control. Release (IF 10.5) Pub Date : 2024-10-25 Xiaorong Yang, Hong Zhang, Zehua Wu, Qin Chen, Wei Zheng, Qiying Shen, Qiaolin Wei, Jia-Wei Shen, Yong Guo
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An ionic liquid-based adjuvant for modulating cellular and humoral immune responses J. Control. Release (IF 10.5) Pub Date : 2024-10-25 Morgan J. Goetz, Kyung Soo Park, Maithili Joshi, Alexander P. Gottlieb, David J. Dowling, Samir Mitragotri
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Choline geranate (CAGE): A multifaceted ionic liquid for drug delivery J. Control. Release (IF 10.5) Pub Date : 2024-10-25 Samir Mitragotri
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Hepatic stellate cell-targeted chemo-gene therapy for liver fibrosis using fluorinated peptide-lipid hybrid nanoparticles J. Control. Release (IF 10.5) Pub Date : 2024-10-25 Qiuyue Lai, Wenlong Li, Dandan Hu, Zhenqiu Huang, Mingyu Wu, Shun Feng, Yu Wan
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Enhancing preventive and therapeutic cancer vaccine efficacy through biotherapeutic ligand-associated extracellular vesicles J. Control. Release (IF 10.5) Pub Date : 2024-10-25 Tamer Kahraman, Gozde Gucluler Akpinar, Muzaffer Yildirim, Pia Larssen, Banu Bayyurt-Kocabas, Fuat C. Yagci, Arda Gursel, Begum Han Horuluoglu, Volkan Yazar, Ihsan Cihan Ayanoglu, Tugce Canavar Yildirim, Irem Evcili, Ismail C. Yilmaz, Maria Eldh, Susanne Gabrielsson, Ulku Guler, Bekir Salih, Mayda Gursel, Ihsan Gursel
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Size-dependent translocation and lymphatic transportation of polymeric nanocarriers post intraperitoneal administration J. Control. Release (IF 10.5) Pub Date : 2024-10-24 Yifan Cai, Zichen Zhang, Chang Liu, Zongguang Tai, Quangang Zhu, Jianping Qi, Yi Lu, Zhongjian Chen, Wei Wu, Haisheng He
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Bioinspired core-shell microparticle for dual-delivery of prebiotic and probiotic for the treatment of ulcerative colitis J. Control. Release (IF 10.5) Pub Date : 2024-10-24 Mengyao Liu, Shuang Ma, Jinglei Zhi, Mingming Wang, Ying Xu, Young-Rok Kim, Ke Luo
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Inulin-based nanoparticles for targeted siRNA delivery in acute kidney injury J. Control. Release (IF 10.5) Pub Date : 2024-10-24 Chinmay M. Jogdeo, Sudipta Panja, Neha Kumari, Weimin Tang, Ekta Kapoor, Kasturi Siddhanta, Ashish Das, Erika I. Boesen, Kirk W. Foster, David Oupický
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The long road of drug development for endometriosis – Pains, gains, and hopes J. Control. Release (IF 10.5) Pub Date : 2024-10-24 Zian Liao, Diana Monsivais, Martin M. Matzuk
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Recent advances in mRNA-based cancer vaccines encoding immunostimulants and their delivery strategies J. Control. Release (IF 10.5) Pub Date : 2024-10-24 Seyyed Majid Eslami, Xiuling Lu
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TME-responsive nanoplatform for multimodal imaging-guided synergistic precision therapy of esophageal cancer via inhibiting HIF-1α signal pathway J. Control. Release (IF 10.5) Pub Date : 2024-10-23 Guodong Ren, Xuewei Wang, Zhaobo Yang, Xiaowan Li, Yingyu Ma, Liang Zhou, Lili Yan, Sufang Ma, Lihong Li, Lixia Guo, Boye Zhang, Haipeng Diao, Haojiang Wang, Bin Wang, Li Lu, Chengwu Zhang, Wen Liu
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Prolonged release and antiviral efficacy of HIV fusion inhibitor LP-98-loaded microspheres in rhesus macaques J. Control. Release (IF 10.5) Pub Date : 2024-10-23 Zhe Cong, Yi Wei, Huihui Chong, Dong Zhang, Ling Tong, Jingjing Zhang, Yuanmei Zhu, Zejing Gao, Huijuan Jin, Jiahan Lu, Qiuhan Lu, Ting Chen, Qiang Wei, Guanghui Ma, Yuxian He, Fangling Gong, Jing Xue
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Overcoming multiple barriers to deliver photo-gene system for glioma-targeted combined therapy J. Control. Release (IF 10.5) Pub Date : 2024-10-24 Yanhui Qin, Lan Yang, Yafeng Yang, Wenjia Gao, Kamiran Aihemaiti, Guangwei Jiang, Rong Huang, Haroon Khan, Rongqin Huang
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Targeted nanoliposomes of oncogenic protein degraders: Significant inhibition of tumor in lung-cancer bearing mice J. Control. Release (IF 10.5) Pub Date : 2024-10-23 Richa Vartak, Ketan Patel
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Mastoid approach for local drug delivery to the inner ear for treating hearing loss J. Control. Release (IF 10.5) Pub Date : 2024-10-23 Yanjiao Ding, Zhiqiang Hou, Mingming Wang, Lei Xu, Haibo Wang
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Low-boiling-point perfluorocarbon nanodroplets for adaptable ultrasound-induced blood-brain barrier opening J. Control. Release (IF 10.5) Pub Date : 2024-10-23 Ambre Dauba, Claire Spitzlei, Kathlyne Jayne B. Bautista, Laurène Jourdain, Erwan Selingue, Kelly E. VanTreeck, Jacob A. Mattern, Caroline Denis, Malika Ouldali, Ana-Andreea Arteni, Charles Truillet, Benoit Larrat, James Tsuruta, Phillip G. Durham, Virginie Papadopoulou, Paul A. Dayton, Nicolas Tsapis, Anthony Novell
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Nanoparticle-mediated synergistic disruption of tumor innervation and redox homeostasis for potent antineoplastic therapy J. Control. Release (IF 10.5) Pub Date : 2024-10-23 Jie He, Xingli Zhang, Haiyan Xing, Jiangwei Tan, Lei Zhang, Zhigang Xu, Yuejun Kang, Peng Xue
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Omnidirectional improvement of mitochondrial health in Alzheimer's disease by multi-targeting engineered activated neutrophil exosomes J. Control. Release (IF 10.5) Pub Date : 2024-10-23 Lei Zhang, Jiaquan Lin, Kai Xiang, Tianshu Shi, Baosheng Guo
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Injectable self-assembling peptide hydrogel as a promising vitreous substitute J. Control. Release (IF 10.5) Pub Date : 2024-10-21 Yuting Cai, Yatong Xiang, Huilei Dong, Wenjing Huang, Yan Liu, Chenguang Zhao, Dan Yuan, Yun Li, Junfeng Shi
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Paracyclophane-based ionizable lipids for efficient mRNA delivery in vivo J. Control. Release (IF 10.5) Pub Date : 2024-10-20 Shiqi Wu, Kexin Su, Xinxin Yan, Lu Shi, Lixin Lin, En Ren, Jingjing Zhou, Chao Zhang, Yanmin Song, Shuai Liu