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Rape, Homicide, and Abortion Bans — The Abandonment of People Subjected to Sexual and Intimate Partner Violence N. Engl. J. Med. (IF 96.2) Pub Date : 2024-07-20 Elizabeth Tobin-Tyler, and Samuel L. Dickman From the School of Public Health and the Warren Alpert Medical School, Brown University, Providence, RI (E.T.-T.), and Planned Parenthood of Montana, Billings (S.L.D.).
Violence against women receives little attention from policymakers and courts. State policymakers who have implemented abortion bans ignore the connections between pregnancy and violence.
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What will it take to make precision health a global reality Nat. Med. (IF 58.7) Pub Date : 2024-07-19
As healthcare becomes more data-driven and precise, promising greater accuracy, targeted use of resources and healthier populations, we ask what it will take to realize these benefits in local and global contexts.
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Dopamine-mediated interactions between short- and long-term memory dynamics Nature (IF 50.5) Pub Date : 2024-07-22 Cheng Huang, Junjie Luo, Seung Je Woo, Lucas A. Roitman, Jizhou Li, Vincent A. Pieribone, Madhuvanthi Kannan, Ganesh Vasan, Mark J. Schnitzer
In dynamic environments, animals make behavioral decisions based on the innate valences of sensory cues and information learnt about these cues across multiple timescales1–3. However, it remains unclear how the innate valence of a sensory stimulus affects acquisition of learnt valence information and subsequent memory dynamics. Here we show that in the Drosophila brain, interconnected short- and long-term
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Found: the hidden link between star-forming molecular clouds Nature (IF 50.5) Pub Date : 2024-07-19
Connections between three interstellar clouds of gas and dust offer a glimpse into their birth.
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Fit for work? The relationship between health and employment will become an increasingly pressing problem BMJ (IF 93.6) Pub Date : 2024-07-19 Lara Shemtob, Rabeea F Khan
The question of fitness for work is most visible in positions of power, but it has widespread relevance, say Lara Shemtob and Rabeea F Khan Is President Biden fit to run for office from a health perspective? If not, is he fit to be in post now? What about Donald Trump’s fitness to run for office? These questions have dogged the US presidential race and have gathered considerable momentum in the media
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Disrupted neural rhythms predict response in deep brain stimulation for OCD Nat. Med. (IF 58.7) Pub Date : 2024-07-19
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Sleep patterns and risk of chronic disease as measured by long-term monitoring with commercial wearable devices in the All of Us Research Program Nat. Med. (IF 58.7) Pub Date : 2024-07-19 Neil S. Zheng, Jeffrey Annis, Hiral Master, Lide Han, Karla Gleichauf, Jack H. Ching, Melody Nasser, Peyton Coleman, Stacy Desine, Douglas M. Ruderfer, John Hernandez, Logan D. Schneider, Evan L. Brittain
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Integrated image-based deep learning and language models for primary diabetes care Nat. Med. (IF 58.7) Pub Date : 2024-07-19 Jiajia Li, Zhouyu Guan, Jing Wang, Carol Y. Cheung, Yingfeng Zheng, Lee-Ling Lim, Cynthia Ciwei Lim, Paisan Ruamviboonsuk, Rajiv Raman, Leonor Corsino, Justin B. Echouffo-Tcheugui, Andrea O. Y. Luk, Li Jia Chen, Xiaodong Sun, Haslina Hamzah, Qiang Wu, Xiangning Wang, Ruhan Liu, Ya Xing Wang, Tingli Chen, Xiao Zhang, Xiaolong Yang, Jun Yin, Jing Wan, Wei Du, Ten Cheer Quek, Jocelyn Hui Lin Goh, Dawei
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Reporting guidelines for precision medicine research of clinical relevance: the BePRECISE checklist Nat. Med. (IF 58.7) Pub Date : 2024-07-19 Siew S. Lim, Zhila Semnani-Azad, Mario L. Morieri, Ashley H. Ng, Abrar Ahmad, Hugo Fitipaldi, Jacqueline Boyle, Christian Collin, John M. Dennis, Claudia Langenberg, Ruth J. F. Loos, Melinda Morrison, Michele Ramsay, Arun J. Sanyal, Naveed Sattar, Marie-France Hivert, Maria F. Gomez, Jordi Merino, Deirdre K. Tobias, Michael I. Trenell, Stephen S. Rich, Jennifer L. Sargent, Paul W. Franks
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Challenges to identifying risk versus protective factors in Alzheimer’s disease Nat. Med. (IF 58.7) Pub Date : 2024-07-18 Chiara Pappalettera, Claudia Carrarini, Stefano Cappa, Naike Caraglia, Maria Cotelli, Camillo Marra, Daniela Perani, Alberto Redolfi, Patrizia Spadin, Fabrizio Tagliavini, Nicola Vanacore, Fabrizio Vecchio, Paolo Maria Rossini
arising from J. Fortea et al. Nature Medicine https://doi.org/10.1038/s41591-024-02931-w (2024) Alzheimer’s disease (AD), a neurodegenerative disorder characterized by a progressive loss of cognitive functioning and independence in daily living, remains an unsolved challenge in modern health organization1,2.
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Reply to: Challenges to identifying risk versus protective factors in Alzheimer’s disease Nat. Med. (IF 58.7) Pub Date : 2024-07-18 Juan Fortea, Lídia Vaqué-Alcázar, Jordi Pegueroles, Daniel Alcolea, Olivia Belbin, Oriol Dols-Icardo, Laura Videla, Juan Domingo Gispert, Marc Suárez-Calvet, Sterling C. Johnson, Reisa Sperling, Alexandre Bejanin, Alberto Lleó, Víctor Montal
replying to C. Pappalettera et al. Nat. Med. https://doi.org/10.1038/s41591-024-03158-5 (2024) Pappalettera et al.1 raise important points concerning our recent publication on APOE4 homozygotes2, specifically about the definition of Alzheimer’s disease (AD), resilience factors, and the ethical implications of diagnosing asymptomatic individuals. We welcome the opportunity to clarify these points, emphasizing
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China–US research collaborations are in decline — this is bad news for everyone Nature (IF 50.5) Pub Date : 2024-07-19
Scientists say that the drop in partnerships between the scientific powerhouses will hold back research on priorities such as global warming.
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Hundreds of racist plant names will change after historic vote by botanists Nature (IF 50.5) Pub Date : 2024-07-18
Scientific designations containing a racial slur will be altered — the first time that any species names have been adjusted because of the offence they cause.
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NASA cancels $450-million mission to drill for ice on the Moon — surprising researchers Nature (IF 50.5) Pub Date : 2024-07-18
The already-built rover could now be scrapped for parts.
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Long COVID lung damage linked to immune system response Nature (IF 50.5) Pub Date : 2024-07-18
Inhibiting a protein associated with chronic inflammation improves lung health in mice with COVID-19.
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Three-year delay for Indian census frustrates researchers Nature (IF 50.5) Pub Date : 2024-07-18
Without up-to-date data on the population, scientists say studies on fertility, migration and health outcomes have become unreliable.
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Daily briefing: Blocking an inflammation protein lets mice live longer Nature (IF 50.5) Pub Date : 2024-07-18
Mice live longer and healthier when the inflammation-boosting protein IL-11 is blocked. Plus, how magic mushrooms reset your sense of time and self.
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What is it like to attend a predatory conference? Nature (IF 50.5) Pub Date : 2024-07-18
Nature sent a reporter to find out as part of an investigation into dud events.
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Even with no drug or vaccine, eradication of Guinea worm is in sight Nature (IF 50.5) Pub Date : 2024-07-18
Community-based efforts have reduced the parasitic infection to a handful of cases in humans each year, but the emergence of infections in dogs and other animals threatens to derail progress.
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This tiny solar-powered flyer weighs less than a paper plane Nature (IF 50.5) Pub Date : 2024-07-17
The 4.21g rotorcraft — dubbed CoulombFly — could forge a path to new kinds of tiny aerial vehicles.
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The enduring world forest carbon sink Nature (IF 50.5) Pub Date : 2024-07-17 Yude Pan, Richard A. Birdsey, Oliver L. Phillips, Richard A. Houghton, Jingyun Fang, Pekka E. Kauppi, Heather Keith, Werner A. Kurz, Akihiko Ito, Simon L. Lewis, Gert-Jan Nabuurs, Anatoly Shvidenko, Shoji Hashimoto, Bas Lerink, Dmitry Schepaschenko, Andrea Castanho, Daniel Murdiyarso
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Symbolic recording of signalling and cis-regulatory element activity to DNA Nature (IF 50.5) Pub Date : 2024-07-17 Wei Chen, Junhong Choi, Xiaoyi Li, Jenny F. Nathans, Beth Martin, Wei Yang, Nobuhiko Hamazaki, Chengxiang Qiu, Jean-Benoît Lalanne, Samuel Regalado, Haedong Kim, Vikram Agarwal, Eva Nichols, Anh Leith, Choli Lee, Jay Shendure
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Giant chiral magnetoelectric oscillations in a van der Waals multiferroic Nature (IF 50.5) Pub Date : 2024-07-17 Frank Y. Gao, Xinyue Peng, Xinle Cheng, Emil Viñas Boström, Dong Seob Kim, Ravish K. Jain, Deepak Vishnu, Kalaivanan Raju, Raman Sankar, Shang-Fan Lee, Michael A. Sentef, Takashi Kurumaji, Xiaoqin Li, Peizhe Tang, Angel Rubio, Edoardo Baldini
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Superconductivity in pressurized trilayer La4Ni3O10−δ single crystals Nature (IF 50.5) Pub Date : 2024-07-17 Yinghao Zhu, Di Peng, Enkang Zhang, Bingying Pan, Xu Chen, Lixing Chen, Huifen Ren, Feiyang Liu, Yiqing Hao, Nana Li, Zhenfang Xing, Fujun Lan, Jiyuan Han, Junjie Wang, Donghan Jia, Hongliang Wo, Yiqing Gu, Yimeng Gu, Li Ji, Wenbin Wang, Huiyang Gou, Yao Shen, Tianping Ying, Xiaolong Chen, Wenge Yang, Huibo Cao, Changlin Zheng, Qiaoshi Zeng, Jian-gang Guo, Jun Zhao
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Inhibition of IL-11 signalling extends mammalian healthspan and lifespan Nature (IF 50.5) Pub Date : 2024-07-17 Anissa A. Widjaja, Wei-Wen Lim, Sivakumar Viswanathan, Sonia Chothani, Ben Corden, Cibi Mary Dasan, Joyce Wei Ting Goh, Radiance Lim, Brijesh K. Singh, Jessie Tan, Chee Jian Pua, Sze Yun Lim, Eleonora Adami, Sebastian Schafer, Benjamin L. George, Mark Sweeney, Chen Xie, Madhulika Tripathi, Natalie A. Sims, Norbert Hübner, Enrico Petretto, Dominic J. Withers, Lena Ho, Jesus Gil, David Carling, Stuart
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An engineered enzyme embedded into PLA to make self-biodegradable plastic Nature (IF 50.5) Pub Date : 2024-07-17 M. Guicherd, M. Ben Khaled, M. Guéroult, J. Nomme, M. Dalibey, F. Grimaud, P. Alvarez, E. Kamionka, S. Gavalda, M. Noël, M. Vuillemin, E. Amillastre, D. Labourdette, G. Cioci, V. Tournier, V. Kitpreechavanich, P. Dubois, I. André, S. Duquesne, A. Marty
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Thresholds for adding degraded tropical forest to the conservation estate Nature (IF 50.5) Pub Date : 2024-07-17 Robert M. Ewers, C. David L. Orme, William D. Pearse, Nursyamin Zulkifli, Genevieve Yvon-Durocher, Kalsum M. Yusah, Natalie Yoh, Darren C. J. Yeo, Anna Wong, Joseph Williamson, Clare L. Wilkinson, Fabienne Wiederkehr, Bruce L. Webber, Oliver R. Wearn, Leona Wai, Maisie Vollans, Joshua P. Twining, Edgar C. Turner, Joseph A. Tobias, Jack Thorley, Elizabeth M. Telford, Yit Arn Teh, Heok Hui Tan, Tom Swinfield
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Adaptation to photoperiod via dynamic neurotransmitter segregation Nature (IF 50.5) Pub Date : 2024-07-17 G. Maddaloni, Y. J. Chang, R. A. Senft, S. M. Dymecki
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A hot-Jupiter progenitor on a super-eccentric retrograde orbit Nature (IF 50.5) Pub Date : 2024-07-17 Arvind F. Gupta, Sarah C. Millholland, Haedam Im, Jiayin Dong, Jonathan M. Jackson, Ilaria Carleo, Jessica Libby-Roberts, Megan Delamer, Mark R. Giovinazzi, Andrea S. J. Lin, Shubham Kanodia, Xian-Yu Wang, Keivan Stassun, Thomas Masseron, Diana Dragomir, Suvrath Mahadevan, Jason Wright, Jaime A. Alvarado-Montes, Chad Bender, Cullen H. Blake, Douglas Caldwell, Caleb I. Cañas, William D. Cochran, Paul
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Psilocybin desynchronizes the human brain Nature (IF 50.5) Pub Date : 2024-07-17 Joshua S. Siegel, Subha Subramanian, Demetrius Perry, Benjamin P. Kay, Evan M. Gordon, Timothy O. Laumann, T. Rick Reneau, Nicholas V. Metcalf, Ravi V. Chacko, Caterina Gratton, Christine Horan, Samuel R. Krimmel, Joshua S. Shimony, Julie A. Schweiger, Dean F. Wong, David A. Bender, Kristen M. Scheidter, Forrest I. Whiting, Jonah A. Padawer-Curry, Russell T. Shinohara, Yong Chen, Julia Moser, Essa
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A eukaryotic-like ubiquitination system in bacterial antiviral defence Nature (IF 50.5) Pub Date : 2024-07-17 Lydia R. Chambers, Qiaozhen Ye, Jiaxi Cai, Minheng Gong, Hannah E. Ledvina, Huilin Zhou, Aaron T. Whiteley, Raymond T. Suhandynata, Kevin D. Corbett
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A holistic platform for accelerating sorbent-based carbon capture Nature (IF 50.5) Pub Date : 2024-07-17 Charithea Charalambous, Elias Moubarak, Johannes Schilling, Eva Sanchez Fernandez, Jin-Yu Wang, Laura Herraiz, Fergus Mcilwaine, Shing Bo Peh, Matthew Garvin, Kevin Maik Jablonka, Seyed Mohamad Moosavi, Joren Van Herck, Aysu Yurdusen Ozturk, Alireza Pourghaderi, Ah-Young Song, Georges Mouchaham, Christian Serre, Jeffrey A. Reimer, André Bardow, Berend Smit, Susana Garcia
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Identification of plant transcriptional activation domains Nature (IF 50.5) Pub Date : 2024-07-17 Nicholas Morffy, Lisa Van den Broeck, Caelan Miller, Ryan J. Emenecker, John A. Bryant, Tyler M. Lee, Katelyn Sageman-Furnas, Edward G. Wilkinson, Sunita Pathak, Sanjana R. Kotha, Angelica Lam, Saloni Mahatma, Vikram Pande, Aman Waoo, R. Clay Wright, Alex S. Holehouse, Max V. Staller, Rosangela Sozzani, Lucia C. Strader
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Position-dependent function of human sequence-specific transcription factors Nature (IF 50.5) Pub Date : 2024-07-17 Sascha H. Duttke, Carlos Guzman, Max Chang, Nathaniel P. Delos Santos, Bayley R. McDonald, Jialei Xie, Aaron F. Carlin, Sven Heinz, Christopher Benner
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Groundwater-dependent ecosystem map exposes global dryland protection needs Nature (IF 50.5) Pub Date : 2024-07-17 Melissa M. Rohde, Christine M. Albano, Xander Huggins, Kirk R. Klausmeyer, Charles Morton, Ali Sharman, Esha Zaveri, Laurel Saito, Zach Freed, Jeanette K. Howard, Nancy Job, Holly Richter, Kristina Toderich, Aude-Sophie Rodella, Tom Gleeson, Justin Huntington, Hrishikesh A. Chandanpurkar, Adam J. Purdy, James S. Famiglietti, Michael Bliss Singer, Dar A. Roberts, Kelly Caylor, John C. Stella
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Singular dielectric nanolaser with atomic-scale field localization Nature (IF 50.5) Pub Date : 2024-07-17 Yun-Hao Ouyang, Hong-Yi Luan, Zi-Wei Zhao, Wen-Zhi Mao, Ren-Min Ma
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Mechanical release of homogenous proteins from supramolecular gels Nature (IF 50.5) Pub Date : 2024-07-17 Simona Bianco, Muhammad Hasan, Ashfaq Ahmad, Sarah-Jane Richards, Bart Dietrich, Matthew Wallace, Qiao Tang, Andrew J. Smith, Matthew I. Gibson, Dave J. Adams
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Clonal inactivation of TERT impairs stem cell competition Nature (IF 50.5) Pub Date : 2024-07-17 Kazuteru Hasegawa, Yang Zhao, Alina Garbuzov, M. Ryan Corces, Patrick Neuhöfer, Victoria M. Gillespie, Peggie Cheung, Julia A. Belk, Yung-Hsin Huang, Yuning Wei, Lu Chen, Howard Y. Chang, Steven E. Artandi
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Sources of gene expression variation in a globally diverse human cohort Nature (IF 50.5) Pub Date : 2024-07-17 Dylan J. Taylor, Surya B. Chhetri, Michael G. Tassia, Arjun Biddanda, Stephanie M. Yan, Genevieve L. Wojcik, Alexis Battle, Rajiv C. McCoy
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Sunlight-powered sustained flight of an ultralight micro aerial vehicle Nature (IF 50.5) Pub Date : 2024-07-17 Wei Shen, Jinzhe Peng, Rui Ma, Jiaqing Wu, Jingyi Li, Zhiwei Liu, Jiaming Leng, Xiaojun Yan, Mingjing Qi
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Tubulin code eraser CCP5 binds branch glutamates by substrate deformation Nature (IF 50.5) Pub Date : 2024-07-17 Jiayi Chen, Elena A. Zehr, James M. Gruschus, Agnieszka Szyk, Yanjie Liu, Martin E. Tanner, Nico Tjandra, Antonina Roll-Mecak
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Bacteria conjugate ubiquitin-like proteins to interfere with phage assembly Nature (IF 50.5) Pub Date : 2024-07-17 Jens Hör, Sharon G. Wolf, Rotem Sorek
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In vivo single-cell CRISPR uncovers distinct TNF programmes in tumour evolution Nature (IF 50.5) Pub Date : 2024-07-17 Peter F. Renz, Umesh Ghoshdastider, Simona Baghai Sain, Fabiola Valdivia-Francia, Ameya Khandekar, Mark Ormiston, Martino Bernasconi, Clara Duré, Jonas A. Kretz, Minkyoung Lee, Katie Hyams, Merima Forny, Marcel Pohly, Xenia Ficht, Stephanie J. Ellis, Andreas E. Moor, Ataman Sendoel
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Split intein-mediated protein trans-splicing to express large dystrophins Nature (IF 50.5) Pub Date : 2024-07-17 Hichem Tasfaout, Christine L. Halbert, Timothy S. McMillen, James M. Allen, Theodore R. Reyes, Galina V. Flint, Dirk Grimm, Stephen D. Hauschka, Michael Regnier, Jeffrey S. Chamberlain
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The plastic that biodegrades in your home compost Nature (IF 50.5) Pub Date : 2024-07-17
Hear the biggest stories from the world of science | 17 July 2024
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Mice live longer when inflammation-boosting protein is blocked Nature (IF 50.5) Pub Date : 2024-07-17
Humans also have the protein, called IL-11, offering hope for a future longevity treatment.
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A psychedelic state arises from desynchronized brain activity Nature (IF 50.5) Pub Date : 2024-07-17 Petros D. Petridis
Psilocybin induces profound changes in brain connectivity.
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Daily briefing: The poetry hidden in PhD thesis acknowledgements Nature (IF 50.5) Pub Date : 2024-07-17
Science writer Tabitha Carvan explores the found poetry in the acknowledgement sections of PhD theses. Plus, researchers should explore the alternatives to animal research and can H5N1 spread through cow sneezes?
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The search for superconductivity just got wider Nature (IF 50.5) Pub Date : 2024-07-17 Weiwei Xie
Evidence of superconductivity in a nickelate under high pressure.
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Your brain on shrooms — how psilocybin resets neural networks Nature (IF 50.5) Pub Date : 2024-07-17
The psychedelic drug causes some lasting changes to the communication pathways that connect distinct brain regions.
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Make gene therapies more available by manufacturing them in lower-income nations Nature (IF 50.5) Pub Date : 2024-07-17 Evelyn Mwesigwa Harlow, Jennifer E. Adair
Gene therapies will become more affordable everywhere only if they are developed and manufactured in the regions of the world most in need of them.
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Forest-degradation thresholds shape tropical biodiversity Nature (IF 50.5) Pub Date : 2024-07-17 Umesh Srinivasan
Framework to assess the conservation value of logged tropical forests.
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Gel protects therapeutic proteins from deactivation — even in the post Nature (IF 50.5) Pub Date : 2024-07-17 Yanxian Zhang, Danny Hung-Chieh Chou
A simple strategy for protecting proteins from heat and vibration.
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Daily briefing: When you should throw away expired reagents Nature (IF 50.5) Pub Date : 2024-07-16
Some lab reagents can work decades beyond their best-before date. Plus, the deepest known pit on the Moon seems to lead to a huge underground cave.
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Covid-19 infection and vaccination during first trimester and risk of congenital anomalies: Nordic registry based study BMJ (IF 93.6) Pub Date : 2024-07-17 Maria C Magnus, Jonas Söderling, Anne K Örtqvist, Anne-Marie Nybo Andersen, Olof Stephansson, Siri E Håberg, Stine Kjaer Urhoj
Objectives To evaluate the risk of major congenital anomalies according to infection with or vaccination against covid-19 during the first trimester of pregnancy. Design Prospective Nordic registry based study. Setting Sweden, Denmark, and Norway. Participants 343 066 liveborn singleton infants in Sweden, Denmark, and Norway, with an estimated start of pregnancy between 1 March 2020 and 14 February
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Trends in long term vaping among adults in England, 2013-23: population based study BMJ (IF 93.6) Pub Date : 2024-07-17 Sarah E Jackson, Harry Tattan-Birch, Lion Shahab, Jamie Brown
Objective To examine trends in long term (>6 months) vaping among adults in England. Design Population based study. Setting England. Participants 179 725 adults (≥18 years) surveyed between October 2013 and October 2023. Main outcome measures Time trends in prevalence of long term vaping using logistic regression, overall and by vaping frequency (daily or non-daily), and main type of device used (disposable
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How do tirzepatide and semaglutide compare for weight loss … and other research BMJ (IF 93.6) Pub Date : 2024-07-18 Tom Nolan
Tom Nolan reviews this week’s research A cohort study of over 18 000 overweight or obese people prescribed tirzepatide or semaglutide for type 2 diabetes in the US compared weight loss over a one year period between the two drugs. By now, it’s no longer surprising that people taking either drug lost weight: 81.8% of those taking tirzepatide and 66.5% of those taking semaglutide achieved at least 5%
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How to avoid bad decisions that can ruin your career BMJ (IF 93.6) Pub Date : 2024-07-18 Daniel Sokol
About once a fortnight I deliver a day long, one-to-one ethics course to a medical student, doctor, or dentist. These clients, usually referred to me by their concerned legal advisers, are undergoing disciplinary proceedings and are fighting for their professional lives. The allegations against them are varied. Some have had sex with patients; some have harassed or bullied colleagues; some have breached
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We urgently need humanised, respectful maternity care for all BMJ (IF 93.6) Pub Date : 2024-07-18 Meghan Bohren, Zoe Bradfield
We must challenge the harmful gender norms and racial inequities that drive poor experiences and health outcomes for women and gender diverse people giving birth and the professionals who care for them, write Meghan Bohren and Zoe Bradfield Maternity services in the United Kingdom are at a precipice. The first Birth Trauma Inquiry paints a harrowing picture of the current state of maternal and newborn
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Will Labour help us transition away from pre-clinical animal research? BMJ (IF 93.6) Pub Date : 2024-07-19 Pandora Pound, Merel Ritskes-Hoitinga
We must develop a funded, evidence based transition programme to enable a shift to safe and effective human biology based approaches in research In February 2024, the Conservative government announced its intention to accelerate the development and uptake of technologies to reduce the use of animals in science, promising publication of a transition strategy this summer.1 Hopes are high that Labour