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A Case of the Non-Caseating Granuloma Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-06-24 Dia R. Waguespack
An abstract is unavailable. This article is available as a PDF only.
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Replacement Strategies for Tunneled Hemodialysis Catheters with Complications: A Nationwide Cohort Study Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-06-24 Benjamin Lazarus, Sradha Kotwal, Martin Gallagher, Nicholas A Gray, Sarah Coggan, Girish Talaulikar, Kevan R Polkinghorne, the REDUCCTION investigators (detailed in Supplemental Item 1)
lacement catheters inserted by either strategy. Methods: Observational data from the REDUCCTION trial, which enrolled a nationwide cohort of 6400 adults who received an incident hemodialysis catheter (2016-2020) was used for this secondary analysis. Tunneled catheters were replaced by either catheter exchange through the existing tunnel tract or removal and replacement through a new tract. The effect
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Sleep Disorders and Dementia Risk in Older Patients with Kidney Failure: A Retrospective Cohort Study Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-06-24 Jane J. Long, Yusi Chen, Byoungjun Kim, Sunjae Bae, Yiting Li, Babak J. Orandi, Nadia M. Chu, Aarti Mathur, Dorry L. Segev, Mara A. McAdams-DeMarco
ith kidney failure (United States Renal Data System; 2008-2019), we estimated the risk of dementia (including subtypes) associated with sleep disorders using Cox proportional-hazard models with propensity score weighting. We tested whether positive airway pressure (PAP) therapy was associated with reduced dementia risk among patients with obstructive sleep apnea (OSA). Results: 26.3% of patients were
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Twice Weekly Versus Thrice Weekly Hemodialysis – A Pilot Cross-Over Equivalence Trial Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-06-26 Seolhyun Lee, Nhat M. Pham, Maria E. Montez-Rath, Christian G. Bolanos, Saniya S. Bonde, Timothy W. Meyer, Tammy L. Sirich
hemodialysis according to this guideline on patients’ quality of life or uremic solute levels. Methods: Twenty six hemodialysis patients with average residual urea clearance (Kru) 4.7±1.8 ml/min and hemodialysis vintage of 12±15 months (range two months to 4.9 years) underwent a cross-over trial comparing four weeks of twice weekly hemodialysis and four weeks of thrice weekly hemodialysis. Twice weekly
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Infection-Related Glomerulonephritis with Cutaneous Vasculitis Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-06-26 Jodi Gedallovich, Ralph M. Mohty, Ksenia Kasimova, Zhengchun Lu, Vivek Charu, John P. Higgins JP, Neeraja Kambham, Vanderlene L. Kung, Megan L. Troxell
An abstract is unavailable. This article is available as a PDF only.
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Reframing “Chronicity” with “Urgency” in Chronic Kidney Disease Management Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-06-26 Brendon L Neuen, Katherine R Tuttle, George Bakris, Muthiah Vaduganathan
An abstract is unavailable. This article is available as a PDF only.
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Lessons Learned from HERA: the First Alport Syndrome Therapeutic Clinical Trial Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-06-21 B. André Weinstock
An abstract is unavailable.
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Validation of Non-invasive Detection of Hyperkalemia by Artificial Intelligence Enhanced Electrocardiography in High Acuity Settings Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-06-21 David M. Harmon, Kan Liu, Jennifer Dugan, Jacob C. Jentzer, Zachi I. Attia, Paul A. Friedman, John J. Dillon
e care unit (ICU) cohort (August 2017-February 2018) were identified and analyzed separately. For each group, pairs of laboratory-collected potassium and 12 lead ECGs obtained within four hours of each other were identified. The previously developed AI ECG algorithm was subsequently applied to leads I and II of the 12 lead ECGs to screen for hyperkalemia (potassium > 6.0 mEq/L). Results: The ED cohort
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Natural killer cell-mediated innate microvascular rejection Nat. Rev. Nephrol. (IF 28.6) Pub Date : 2024-06-19 Olivier Thaunat
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Unlocking the benefits of transplantation with kidneys from older donors Nat. Rev. Nephrol. (IF 28.6) Pub Date : 2024-06-18 Vidya A. Fleetwood, Krista L. Lentine
Kidneys from older donors might improve the quality of life and survival of patients with kidney failure, yet these organs are often underutilized. Re-framing discussions of organ acceptance from older donors and its benefits over dialysis, especially for older patients and those who cannot tolerate prolonged waiting for transplantation, is urgently needed.
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Pulmonary hypertension and chronic kidney disease: prevalence, pathophysiology and outcomes Nat. Rev. Nephrol. (IF 28.6) Pub Date : 2024-06-18 Katarina Zeder, Edward D. Siew, Gabor Kovacs, Evan L. Brittain, Bradley A. Maron
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Chronic Tonsillitis and IgA Nephropathy: Findings From a Nationwide Japanese Cohort Study Am. J. Kidney Dis. (IF 9.4) Pub Date : 2024-06-19 Takashin Nakayama MD, Hidehiro Kaneko MD, Yuta Suzuki PhD, Akira Okada MD, Hiroyuki Morita MD, Katsuhito Fujiu MD, Norifumi Takeda MD, Akira Fukui MD, Takashi Yokoo MD, Norihiko Takeda MD, Hideo Yasunaga MD, Masaomi Nangaku MD, Kaori Hayashi MD.
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Comparison of cardiac autonomic innervation in post-mortem tissue from individuals with kidney failure and preserved kidney function Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-06-13 Qandeel Soomro, Valeria Mezzano, Navneet Narula, Amy Rapkiewicz, Cynthia Loomis, David M. Charytan
An abstract is unavailable. This article is available as a PDF only.
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A Six-Year Follow-Up of Bloodstream Infections in Hemodialysis Facilities in the United States, National Healthcare Safety Network, 2020 Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-06-18 John Keenan, Kira A. Barbre, Philip Dollard, Tamara Hoxworth, Iram Qureshi, Lindsay Dunham, Erin O'Leary, Selom Agbobli Nuwoaty, Suparna Bagchi, Jonathan Edwards, Mary Lu, Andrea Benin, Jeneita Bell
BSI events divided by the predicted number of events based on national aggregate data. Median facility-level standardized infection ratios and 95% confidence intervals (CIs) were stratified by state and US territory. Results During 2020, 7,183 outpatient hemodialysis facilities reported data for 5,235,234 patient months with 15,181 BSI events. Pooled mean rates per 100 person-months were 0.29 (95%
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Healthy ageing and the kidney — lessons from centenarians Nat. Rev. Nephrol. (IF 28.6) Pub Date : 2024-06-17 Yasumichi Arai, Motoko Yanagita
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Gene regulatory networks in disease and ageing Nat. Rev. Nephrol. (IF 28.6) Pub Date : 2024-06-12 Paula Unger Avila, Tsimafei Padvitski, Ana Carolina Leote, He Chen, Julio Saez-Rodriguez, Martin Kann, Andreas Beyer
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Frailty and Duration of Maintenance Dialysis: A Japanese Nationwide Cross-Sectional Study Am. J. Kidney Dis. (IF 9.4) Pub Date : 2024-06-12 Suguru Yamamoto MD PhD, Kakuya Niihata MD PhD, Tatsunori Toida MD PhD, Masanori Abe MD PhD, Norio Hanafusa MD PhD, Noriaki Kurira MD PhD
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How We Treat Dyslipidemia in Prolonged Nephrotic Syndrome Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-06-12 Claudio Ponticelli, Lorenzo Arnaboldi, Gabriella Moroni, Alessia Fornoni
An abstract is unavailable. This article is available as a PDF only.
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Mechanisms of antihypertensive effect of chlorthalidone in advanced chronic kidney disease—a causal mediation analysis Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-06-12 Rajiv Agarwal, Arjun D Sinha, Wanzhu Tu
prespecified analysis, we analyzed the contributions of baseline levels of 24-hour urinary sodium and aldosterone and the changes from baseline to 4 weeks in the multiple mediators reflecting volume status in a causal mediation analysis framework. Baseline levels of these mediators served as covariates. No power calculationfor this analysis was performed. Results: Of the 160 patients randomized, 140
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Patient and Caregiver Perspective on PRO-Kid Quality of Life Tool Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-06-12 Lisa Bonebrake, Afton DeLucca
An abstract is unavailable.
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The Promise and Challenges of Metabolomic Studies in Pediatric CKD Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-06-12 Sahir Kalim, William E. Smoyer
An abstract is unavailable.
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Dynamic Individualized Risk Prediction in IgA Nephropathy: Entering the Era of Artificial Intelligence Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-06-12 Haresh Selvaskandan, Jonathan Barratt
An abstract is unavailable.
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Assessment of Glomerular Filtration Rate in Patients with Cancer: A Statement from the American Society of Onco-Nephrology Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-06-07 Abhijat Kitchlu, Verônica T. Costa E Silva, Shuchi Anand, Jaya Kala, Ala Abudayyeh, Lesley A. Inker, Mitchell H. Rosner, Sabine Karam, Prakash Gudsoorkar, Shruti Gupta, Sheldon Chen, Nattawat Klomjit, Nelson Leung, Tomaz Milanez, Shveta S. Motwani, Sheikh B. Khalid, Vinay Srinivasan, Rimda Wanchoo, Jan H. Beumer, Geoffrey Liu, Nizar M. Tannir, Ani Orchanian-Cheff, Yimin Geng, Sandra M. Herrmann
nancy and treatment may cause kidney injury and subsequent CKD. To date, there has been lack of guidance to standardize approaches to GFR estimation in the cancer population. In this two-part statement from the American Society of Onco-Nephrology, we present key messages for estimation of GFR in patients with cancer, including the choice of GFR estimating equation, use of race and body surface-area
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Assessment of GFR in Patients with Cancer Part 2: Anticancer Therapies – Perspectives from the ASON Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-06-07 Abhijat Kitchlu, Verônica T. Costa E Silva, Shuchi Anand, Jaya Kala, Ala Abudayyeh, Lesley A. Inker, Mitchell H. Rosner, Sabine Karam, Prakash Gudsoorkar, Shruti Gupta, Sheldon Chen, Nattawat Klomjit, Nelson Leung, Tomaz Milanez, Shveta S. Motwani, Sheikh B. Khalid, Vinay Srinivasan, Rimda Wanchoo, Jan H. Beumer, Geoffrey Liu, Nizar M. Tannir, Ani Orchanian-Cheff, Yimin Geng, Sandra M. Herrmann
An abstract is unavailable. This article is available as a PDF only.
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C3 Glomerulopathy Recurs Early after Kidney Transplantation in Serial Biopsies Performed within the First Two Years Post-Transplantation Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-06-07 Blanca Tarragón, Yonatan Peleg, Geetha Jagannathan, Miroslav Sekulic, Jae-Hyung Chang, David J Cohen, Russell J Crew, Geoffrey K Dube, Hilda E Fernandez, Syed Ali Husain, Sumit Mohan, Heather K Morris, Gerald Appel, Paresh Jadav, Dominick Santoriello, Satoru Kudose, M Barry Stokes, Ibrahim Batal, Andrew Bomback
ent C3G are scarce. We aimed to evaluate C3G recurrence in the allograft, with a focus on histologic presentation and progression. Methods We retrospectively analyzed 18 patients with native kidney failure attributed to C3G (12 C3GN and six DDD) who received a kidney transplant from January 2016 to January 2023. Demographic, genetic, clinical, and histologic data were studied. The Nanostring 770 genes
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Averaged versus Persistent Reduction in Urine Output to Define Oliguria in Critically Ill Patients, an Observational Study. Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-06-07 Céline Monard, Nathan Bianchi, Tatiana Kelevina, Marco Altarelli, Aziz Chaouch, Antoine Schneider
c dialysis or who declined consent. We extracted hourly UO and, across six hours sliding time-windows, assessed for the presence of oliguria according to the average (mean UO below threshold) and persistent method (all measurements below threshold). For both methods, we compared oliguria’s incidence and association with 90-day mortality, and acute kidney disease (AKD) at hospital discharge. Results:
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Effects of individualized anemia therapy on hemoglobin stability: a randomized controlled pilot trial in hemodialysis patients. Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-06-11 Doris H. Fuertinger, Lin-Chun Wang, David J. Jörg, Lemuel Rivera Fuentes, Xiaoling Ye, Sabrina Casper, Hanjie Zhang, Ariella Mermelstein, Alhaji Cherif, Kevin Ho, Jochen G. Raimann, Lela Tisdale, Peter Kotanko, Stephan Thijssen
ontrolled trial comparing our anemia therapy assistance software against a standard population-based anemia treatment protocol. We hypothesized that personalized dosing of erythropoiesis stimulating agents (ESA) improves hemoglobin target attainment. Methods: Ninety-six patients undergoing hemodialysis and receiving methoxy polyethylene glycol-epoetin beta were randomized 1:1 to the intervention group
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Validation of Patient-Reported Outcome measure in pediatric chronic Kidney disease (PRO-Kid) Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-06-11 Mina Matsuda-Abedini, Michael Zappitelli, Kimberley Widger, Adam Rapoport, Janis M Dionne, Rahul Chanchlani, Susan Samuel, Sara N. Davison, Ke Fan Bei, Veronica Ka Wai Lai, Brenden Dufault, Allison B. Dart
ptoms in children. In the current study, we further assessed the validity and internal consistency of PRO-Kid. Methods: In this multicenter study, children age 8 to 18 years with stages 3-5 CKD, including those on dialysis, were recruited from five pediatric centers. Children completed the 14-item PRO-Kid questionnaire and the validated Pediatric Quality of Life Inventory (PedsQL™ 4.0). We explored
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DEVELOPING THERAPIES FOR C3G: REPORT OF THE KIDNEY HEALTH INITIATIVE C3G TRIAL ENDPOINTS WORK GROUP Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-06-03 Carla Nester, Dima A. Decker, Matthias Meier, Shakil Aslam, Andrew S. Bomback, Fernando Caravaca-Fontán, Terence H. Cook, David L. Feldman, Veronique Fremeaux-Bacchi, Daniel P. Gale, Ann Gooch, Sally Johnson, Christoph Licht, Mohit Mathur, Matthew C. Pickering, Manuel Praga, Giuseppe Remuzzi, Viknesh Selvarajah, Richard J. Smith, Hossein Tabriziani, Nicole van de Kar, Yaqin Wang, Edwin Wong, Kirtida
especified trial endpoints as measures of clinical benefit; and (2) opine on efficacy findings they would consider compelling as treatment(s) for C3G in native kidneys. Two subpanels of the C3G Trial Endpoints Work group reviewed the available evidence and uncertainties for the association between the three prespecified endpoints -- (1) proteinuria; (2) estimated glomerular filtration rate (eGFR);
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A Randomized Controlled Clinical Trial Testing Effects of Lademirsen on Kidney Function Decline in Adults with Alport Syndrome Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-06-03 Daniel P. Gale, Oliver Gross, Fang Wang, Rafael José Esteban de la Rosa, Matthew Hall, John A. Sayer, Gerald Appel, Ali Hariri, Shiguang Liu, Manish Maski, Yuqian Shen, Qi Zhang, Sajida Iqbal, Madhurima Uppara Kowthalam, Julie Lin, Jie Ding, on behalf of the HERA Clinical Trial Group
glomerular filtration rate (eGFR) decline in adults with Alport syndrome at risk of rapid disease progression. Methods: This study was a phase 2 trial of lademirsen, with a randomized, double-blind, placebo-controlled period followed by an open-label period. Adults with Alport syndrome, eGFR >35 to <90 mL/min/1.73 m2, and evidence of rapidly progressive kidney dysfunction were randomized 2:1 to lademirsen
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Chronic kidney disease in American Indians and Alaska Natives Nat. Rev. Nephrol. (IF 28.6) Pub Date : 2024-06-07 Vallabh O. Shah, Tassy Parker, Giselle Rodriguez de Sosa, Mark L. Unruh
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Identifying Major Barriers to Home Dialysis (The IM-HOME Study): Findings From a National Survey of Patients, Care Partners, and Providers Am. J. Kidney Dis. (IF 9.4) Pub Date : 2024-06-06 Yuvaram N.V. Reddy MBBS MPH, Matthew D. Kearney PhD MPH, Michaela Ward MS Ed, Robert E. Burke MD MS, Ann M. O’Hare MA MD, Peter P. Reese MD PhD, Meghan B. Lane-Fall MD MSHP, IM-HOME Advisory Board, Jennifer Jones, Frank Liu, Ashley Martin, April McGraw, Joanna Neumann, Amber Pettis, Page Salenger
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Kidney Care in Times of Crises: A Review Am. J. Kidney Dis. (IF 9.4) Pub Date : 2024-06-06 Sami Alasfar MD MPH, Sahar H. Koubar MD, Samir C. Gautam MD, Bernard G. Jaar MD MPH
The global burden of kidney disease is increasing, paralleled by a rising number of natural and man-made crises. During these tumultuous times, accessing vital healthcare resources becomes challenging, posing significant risks to individuals, particularly those with kidney disease. This review delves into the impact of crises on kidney disease, with a particular focus on acute kidney injury (AKI),
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Home monitoring of patients with chronic kidney disease Nat. Rev. Nephrol. (IF 28.6) Pub Date : 2024-06-04 Sabine H. Josemans, Lucas Lindeboom, Karin G. F. Gerritsen, Fokko P. Wieringa, Jeroen P. Kooman, Joris I. Rotmans
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The role of complement in kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference Kidney Int. (IF 14.8) Pub Date : 2024-06-04 Marina Vivarelli, Jonathan Barratt, Laurence H. Beck Jr., Fadi Fakhouri, Daniel P. Gale, Elena Goicoechea de Jorge, Marta Mosca, Marina Noris, Matthew C. Pickering, Katalin Susztak, Joshua M. Thurman, Michael Cheung, Jennifer M. King, Michel Jadoul, Wolfgang C. Winkelmayer, Richard J.H. Smith, for Conference Participants, Federico Alberici, Luca Antonucci, Tadej Avcin, Arvind Bagga, Ingeborg M. Bajema
Uncontrolled complement activation can cause or contribute to glomerular injury in multiple kidney diseases. Although complement activation plays a causal role in atypical hemolytic uremic syndrome and C3 glomerulopathy, over the past decade, a rapidly accumulating body of evidence has shown a role for complement activation in multiple other kidney diseases, including diabetic nephropathy and several
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Cystatin C and the misdiagnosis of CKD in older adults Nat. Rev. Nephrol. (IF 28.6) Pub Date : 2024-06-03 Andrew D. Rule, Richard J. Glassock
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Mutational signatures of ccRCC vary between geographical regions Nat. Rev. Nephrol. (IF 28.6) Pub Date : 2024-05-31 Ellen F. Carney
Known risk factors, such as smoking, obesity and hypertension, do not explain variations in the incidence of clear cell renal cell carcinoma (ccRCC) between different geographical regions. A new study reports that the somatic mutation profiles of ccRCC differ between countries, which indicates substantial geographical variations in mutagenic exposures. To investigate mutational signatures in ccRCC
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VHL loss attracts immune cells to tumours Nat. Rev. Nephrol. (IF 28.6) Pub Date : 2024-05-31 Monica Wang
VHL loss is common in clear cell renal cell carcinoma (ccRCC) and triggers a pseudohypoxic state in mutated cells. A study by Jeffrey Rathmell and colleagues now suggests that Vhl deletion also affects the tumour immune-cell infiltrate in RCC. The myeloid cells that infiltrated Vhl−/− tumours were also functionally distinct from those in control tumours, as they were more phagocytic ex vivo and had
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Remodelling by macula densa cells Nat. Rev. Nephrol. (IF 28.6) Pub Date : 2024-05-30 Susan J. Allison
Cells of the macula densa (MD) sense changes in tubular fluid to control functions such as renal blood flow and renin release. New findings identify a broader role for MD cells in the remodelling of kidney tissue. “The identified cell … features … suggest that the MD is a much more complex and key sensory and regulatory cell type in the nephron than previously thought,” say the researchers. To study
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Platelets, inflammation, and purinergic receptors in chronic kidney disease Kidney Int. (IF 14.8) Pub Date : 2024-05-29 Adam L. Corken, Vincz Ong, Rajshekhar Kore, Sai N. Ghanta, Oleg Karaduta, Rupak Pathak, Shannon Rose, Craig Porter, Nishank Jain
Platelets are anucleated cells that circulate in the bloodstream. Historically, platelets were thought to perform a singular function—stop bleeding via clotting. Although platelets do play a key role in hemostasis and thrombosis, recent studies indicate that platelets also modulate inflammation, and this platelet-induced inflammation contributes to the pathophysiology of various diseases such as atherosclerosis
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Signaling through cAMP-Epac1 induces metabolic reprogramming to protect podocytes in glomerulonephritis Kidney Int. (IF 14.8) Pub Date : 2024-05-29 Lilia Abbad, Maximin Détrait, Panagiotis Kavvadas, Dorian Bergonnier, Lisa Melis, Marion Laudette, Tiffany Migeon, Marie-Christine Verpont, Alexandre Lucas, Christos Chatziantoniou, Frank Lezoualc’h
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DNA-binding protein-A promotes kidney ischemia/reperfusion injury and participates in mitochondrial function Kidney Int. (IF 14.8) Pub Date : 2024-05-29 Charlotte Reichardt, Sabine Brandt, Anja Bernhardt, Anna Krause, Jonathan A. Lindquist, Sönke Weinert, Robert Geffers, Tobias Franz, Sascha Kahlfuss, Anne Dudeck, Akash Mathew, Rajiv Rana, Berend Isermann, Peter R. Mertens
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In Reply to “The Use of Ultrasound in Peritoneal Dialysis Setting” Am. J. Kidney Dis. (IF 9.4) Pub Date : 2024-05-29 Vandana Dua Niyyar MD
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Lower Dosage Acute Peritoneal Dialysis versus Acute Intermittent Hemodialysis in Acute Kidney Injury: A Randomized Controlled Trial Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-05-29 Watanyu Parapiboon, Sajja Tatiyanupanwong, Kamol Khositrangsikun, Thanawat Phulkerd, Piyanut Kaewdoungtien, Watthikorn Pichitporn, Nuttha Lumlertgul, Sadudee Peerapornratana, Fangyue Chen, Nattachai Srisawat
ed controlled trial compared the outcomes between acute lower dosage PD (18-24 liters per day) and Intermittent HD (three times per week) from May 2018 to January 2021 in patients with AKI. The primary outcome was 28-day mortality rate. Secondary outcomes included 28-day dialysis-free survival and kidney recovery, metabolic profile, and procedure-related complications. Non-inferiority of PD to HD would
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Evaluation of glomerular hemodynamic changes by sodium-glucose-transporter 2 inhibition in type 2 diabetic rats using in vivo imaging Kidney Int. (IF 14.8) Pub Date : 2024-05-25 Yoshihisa Wada, Kengo Kidokoro, Megumi Kondo, Atsuyuki Tokuyama, Hiroyuki Kadoya, Hajime Nagasu, Eiichiro Kanda, Tamaki Sasaki, David Z.I. Cherney, Naoki Kashihara
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Sleep disorders in chronic kidney disease Nat. Rev. Nephrol. (IF 28.6) Pub Date : 2024-05-24 Owen D. Lyons
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Environmental pollution to kidney disease: an updated review of current knowledge and future directions Kidney Int. (IF 14.8) Pub Date : 2024-05-24 Xiang Qian Lao, Yacong Bo, Dezhong Chen, Kai Zhang, Cheuk-Chun Szeto
Environmental pollution significantly impacts global disease burden. However, the contribution of environmental pollution to kidney disease is often overlooked in nephrology. This review examines the growing body of research demonstrating the significant impacts of environmental pollutants, with a focus on air pollution as a primary factor, and acknowledges the roles of other pollutants, such as heavy
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Dietary potassium loads call on intercalated cell PIEZO1 to go with the flow Kidney Int. (IF 14.8) Pub Date : 2024-05-24 Seth L. Alper, Fouad T. Chebib
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ZFYVE21 promotes endothelial nitric oxide signaling and vascular barrier function in the kidney during aging Kidney Int. (IF 14.8) Pub Date : 2024-05-24 Quan Jiang, Guiyu Song, Liying He, Xue Li, Bo Jiang, Qianxun Wang, Shaoxun Wang, Catherine Kim, Mahsa Nouri Barkestani, Roberto Lopez, Matthew Fan, Kujani Wanniarachchi, Maya Quaranta, Xuefei Tian, Arya Mani, Anjelica Gonzalez, Julie E. Goodwin, William C. Sessa, Shuta Ishibe, Dan Jane-wit
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A stepped wedge cluster randomized trial of graphical surveillance of kidney function data to reduce late presentation for kidney replacement therapy Kidney Int. (IF 14.8) Pub Date : 2024-05-24 Hugh Gallagher, Shona Methven, Anna Casula, Hugh Rayner, Erik Lenguerrand, Nicola Thomas, Anne Dawnay, David Kennedy, Lesley Woolnough, Michael Nation, Fergus J. Caskey
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Genome-wide association study of hospitalized patients and acute kidney injury Kidney Int. (IF 14.8) Pub Date : 2024-05-24 E.D. Siew, J.N. Hellwege, A.M. Hung, B.C. Birkelo, A.J. Vincz, S.K. Parr, J. Denton, R.A. Greevy, C. Robinson-Cohen, H. Liu, K. Susztak, M.E. Matheny, D.R. Velez Edwards
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DERIVATION AND VALIDATION OF A MACHINE LEARNING MODEL FOR THE PREVENTION OF UNPLANNED DIALYSIS Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-05-24 Martin M. Klamrowski, Ran Klein, Christopher McCudden, James R. Green, Babak Rashidi, Christine A. White, Matthew J. Oliver, Amber O. Molnar, Cedric Edwards, Tim Ramsay, Ayub Akbari, Gregory L. Hundemer
D patients who are at high risk for developing kidney failure over short time frames (6-12 months) may help reduce the rates of unplanned dialysis and improve the quality of transitions from CKD to kidney failure. Methods: We performed a retrospective study employing machine learning random forest algorithms incorporating routinely collected age and sex data along with time-varying trends in laboratory
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Kidney macrophages keep the stones rolling Kidney Int. (IF 14.8) Pub Date : 2024-05-23 Maria B. Rodrigo, Christian Kurts
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Salvaging donated kidneys from prolonged warm ischemia during ex vivo hypothermic oxygenated perfusion Kidney Int. (IF 14.8) Pub Date : 2024-05-22 Peng Zhang, Chao Sun, Shuyong Mo, Chaoyu Hu, Yuxiang Ning, Han Liang, Zhongzhong Liu, Xiaoli Fan, Yanfeng Wang
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The glycolytic enzyme PFKFB3 drives kidney fibrosis through promoting histone lactylation-mediated NF-κB family activation Kidney Int. (IF 14.8) Pub Date : 2024-05-22 Yating Wang, Hongyu Li, Simin Jiang, Dongying Fu, Xiaohui Lu, Miaoqing Lu, Yi Li, Dan Luo, Kefei Wu, Yiping Xu, Guanglan Li, Yi Zhou, Yiming Zhou, Wei Chen, Qinghua Liu, Haiping Mao
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DNA methyltransferase 1 (DNMT1) promotes cyst growth and epigenetic age acceleration in autosomal dominant polycystic kidney disease Kidney Int. (IF 14.8) Pub Date : 2024-05-21 Julie Xia Zhou, Linda Xiaoyan Li, Hongbing Zhang, Ewud Agborbesong, Peter C. Harris, James P. Calvet, Xiaogang Li
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Tauroursodeoxycholic acid ameliorates renal injury induced by COL4A3 mutation Kidney Int. (IF 14.8) Pub Date : 2024-05-21 Shuwen Yu, Xiangchen Gu, Qimin Zheng, Yunzi Liu, Teija Suhas, Wen Du, Lin Xie, Zhengying Fang, Yafei Zhao, Mingxin Yang, Jing Xu, Yimei Wang, Meei-Hua Lin, Xiaoxia Pan, Jeffrey H. Miner, Yuanmeng Jin, Jingyuan Xie
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Vascular Access Considerations in Home Hemodialysis Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-05-21 Ryan J. Chan, Christopher T. Chan
he establishment and maintenance of a functioning vascular access that serves as a patient’s lifeline while on therapy. While the selection of a vascular access type is influenced by individual patient circumstances, the arteriovenous fistula is generally the preferred access method. Training patients to utilize their dialysis access requires attention to safety, risk management, and monitoring for
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Kidney health within the broader non-communicable disease agenda Nat. Rev. Nephrol. (IF 28.6) Pub Date : 2024-05-17 Slim Slama, Valerie A. Luyckx, Bianca Hemmingsen
Kidney disease is strongly linked with cardiovascular diseases, hypertension, diabetes, infections and other health conditions, as well as social determinants of health and climate change. Consequently, a holistic approach to promote well-being, protect individual health and improve access to quality primary care will support kidney health.
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Prescribing Peritoneal Dialysis in the United States Clin. J. Am. Soc. Nephrol. (IF 8.5) Pub Date : 2024-05-17 Matthew B. Rivara, Rajnish Mehrotra
An abstract is unavailable.