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Meta‐Analysis: Prevalence of Frailty and Associated Adverse Events in Inflammatory Bowel Diseases Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-11 Isabel Carbery, Oliver Todd, Matthew Hale, Christopher J. Black, Andrew Clegg, Christian P. Selinger
BackgroundThe number of adults aged over 60 years with inflammatory bowel disease (IBD) is increasing. Frailty, rather than chronological age, may be a better predictor of adverse health outcomes.AimsTo summarise current knowledge about frailty in adults with IBD including the prevalence and associations of frailty and IBD‐related adverse outcomes.MethodsWe performed an electronic search of MEDLINE
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Favourable Prognosis of Patients With Untreated HBeAg‐Negative Chronic Hepatitis B Virus Infection With HBsAg < 100 IU/mL Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-11 Jian Wang, Zhiyi Zhang, Shengxia Yin, Shaoqiu Zhang, Li Zhu, Yifan Pan, Tao Fan, Fei Cao, Ye Xiong, Chao Jiang, Guiyang Wang, Yue Yang, Bei Jia, Jiacheng Liu, Juan Xia, Xiaomin Yan, Jie Li, Chuanwu Zhu, Xingxiang Liu, Yuxin Chen, Chao Wu, Rui Huang
BackgroundSerum hepatitis B surface antigen (HBsAg) < 100 IU/mL has been recently proposed as one of the key criteria of ‘partial cure’ in patients with chronic hepatitis B virus (HBV) infection. We analysed the clinical prognosis of hepatitis B e antigen (HBeAg)‐negative untreated patients with HBsAg < 100 IU/mL and normal alanine aminotransferase (ALT) levels.MethodsFive hundred and twenty‐one untreated
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Factors Associated With Motivation to Reduce Alcohol Use Among Patients With Chronic Liver Disease Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-11 Derek D. Satre, Dhweeja Dasarathy, Steven L. Batki, Michael J. Ostacher, Hannah R. Snyder, William Hua, Priti Parekh, Amy M. Shui, Ramsey Cheung, Alexander Monto, Robert J. Wong, Jennifer Y. Chen, Meimei Liao, Michele Tana, Po‐Hung Chen, Christina G. Haight, Taylor Fakadej, Mandana Khalili
Background and AimsAlcohol use is prevalent among hepatology clinic patients with chronic liver disease (CLD). We explored factors associated with the importance and confidence dimensions of motivation to reduce drinking.MethodsParticipants (N = 121) with unhealthy alcohol use (i.e., over NIH guidelines) receiving care in hepatology clinics from a safety‐net hospital (SN, N = 54) and two Veterans Affairs
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Portal Hypertensive Gastropathy and MELD-Na Score Predict Recurrent Gastrointestinal Bleeding After TIPSS: An ALTA Group Study Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-05 Kelly Hu, Mai Sedki, Allison Kwong, Andrew Kesselman, Kanti Pallav Kolli, Giuseppe Morelli, Erin Spengler, Adnan Said, Jennifer Lai, Archita Desai, Sonali Paul, Catherine Frenette, Michael Fallon, Margarita German, Elizabeth Verna, Justin Boike, Dyanna Gregory, Bartley Thornburg, Lisa VanWagner, Aparna Goel
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Editorial: Food for Thought—Addressing the Nuances of Diet and Mood When Evaluating Dietary Intervention in IBS Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-07 Cecilia Katzenstein, Laurie Keefer
In the study by O'Connor et al. participants with primarily IBS-D undergoing a group-based education program on the British Dietary Association's advice for IBS were less likely to achieve the 12-week primary endpoint (50-point reduction in the IBS Symptom Severity Scale) if they had elevated levels of depression or anxiety at baseline [1]. We appreciate the complex undertaking of evaluating psychological
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Editorial: Food for Thought—Addressing the Nuances of Diet and Mood When Evaluating Dietary Intervention in IBS. Authors' Reply Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-07 Anthony O'Connor, Sarah Gill, Elaine Neary, Sarah White, Alexander C. Ford
We thank Drs Katzenstein and Keefer for their editorial on our paper [1, 2]. We fully agree on the need for progress towards an integrated, personalised model of care for patients with disorders of gut-brain interaction. We are aware of the limitations of the Hospital Anxiety and Depression Scale (HADS) and concur that it does not capture all the psychological nuances seen in patients with irritable
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Letter: Impact of HCV Eradication on Recurrence Pattern and Long‐Term Outcomes in Patients With HCV‐Related Hepatocellular Carcinoma Undergoing Radiofrequency Ablation. Authors' Reply Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-06 Kuo‐Cheng Wu, I‐Cheng Lee
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Editorial: Understanding Factors Associated With Abdominal Pain in Ulcerative Colitis—No Surprises but the Usual Suspects Need Greater Attention. Authors' Reply Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-06 Tom van Gils, Hans Törnblom, Jóhann P. Hreinsson, Börje Jonefjäll, Hans Strid, Magnus Simrén
We thank Dr. Gao and Professor Segal for their interest in our paper on abdominal pain and associated factors in patients with ulcerative colitis (UC) [1, 2]. We agree with them regarding the importance of being aware of abdominal pain in patients with UC, including factors associated with gut-brain interaction, in particular anxiety and depression. Additionally, we agree with the suggestion that predictive
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Editorial: Understanding Factors Associated With Abdominal Pain in Ulcerative Colitis—No Surprises But the Usual Suspects Need Greater Attention Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-06 Weilun Gao, Jonathan P. Segal
Pain control is often multidisciplinary and resource-intensive. Pain may be a poorly controlled symptom of ulcerative colitis (UC) culminating in significant patient dissatisfaction. The multicohort study exploring factors associated with abdominal pain in active and quiescent UC highlights the importance of attempting to prevent pain in UC. This may be achieved through understanding the risk factors
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Letter: ‘Impact of HCV Eradication on Recurrence Pattern and Long‐Term Outcomes in Patients With HCV‐Related Hepatocellular Carcinoma Undergoing Radiofrequency Ablation’ Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-06 You‐Jian Xu, Hui‐Ming Pang
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A Prospective Study on the Prevalence of MASLD in Patients With Type 2 Diabetes and Hyperferritinaemia Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-05 Maral Amangurbanova, Daniel Q. Huang, Nabil Noureddin, Kaleb Tesfai, Richelle Bettencourt, Harris Siddiqi, Scarlett J. Lopez, Vanessa Cervantes, Egbert Madamba, Rohit Loomba
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Editorial: Stopping NUCs—When to Restart NUCs for the Best Outcome? Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-05 Melanie Urbanek‐Quaing, Markus Cornberg
The standard treatment of chronic hepatitis B virus (HBV) infection, nucleos(t)ide analogues (NUC), is usually long-term, as HBsAg loss is rarely achieved, which signifies functional cure. Recent evidence suggests that selected HBeAg-negative individuals with prolonged viral suppression and no advanced liver fibrosis can discontinue NUC therapy before HBsAg loss [1]. Studies, including a prospective
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Editorial: Navigating the Beta‐Blocker Dilemma in Advanced Liver Cirrhosis—When Is the Right Time to Discontinue? Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-05 Louise J. M. Alferink, Robert J. de Knegt
Non-selective beta-blockers (NSBBs) are highly effective in preventing variceal bleeding. They are therefore widely used in patients with liver cirrhosis and portal hypertension [1]. Since the landmark study by Lebrec et al. many studies have investigated NSBB use in cirrhosis, including the controversial paper by Serste et al. which suggested increased mortality in decompensated cirrhosis due to NSBB
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Editorial: Navigating the Beta‐Blocker Dilemma in Advanced Liver Cirrhosis—When Is the Right Time to Discontinue? Authors' Reply Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-05 Ting Wang, Deli Zou, Xingshun Qi
At present, non-selective beta-blockers (NSBBs) are recommended for the management of clinically significant portal hypertension and primary or secondary prophylaxis of variceal bleeding in cirrhosis [1, 2]. However, as mentioned in the editorial by Alferink and de Knegt [3], the right time to discontinue NSBBs remains inconclusive. The window hypothesis, which has been for the first time proposed
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Meta‐Analysis: Global Prevalence of Coeliac Disease in Type 1 Diabetes Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-05 Sahand Karimzadhagh, Elahe Abbaspour, Maryam Shahriarinamin, Pourya Shamsi, Selvana Poursadrolah, Mehrdad Khorasani, Mahzad Daghighi, Arash Malek, Jouan Taheri Talesh, Govind K. Makharia, Mohammad Rostami‐Nejad
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Letter: Assessing the Durability of Treatment Effects: Long‐Term Outcomes of ESWL and ERCP for Pancreatic Duct Stones in Chronic Pancreatitis—Authors' Reply Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-04 Yu Liu, Liang‐Hao Hu
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Letter: Timely Follow‐Up in Cirrhosis—A Key Public Health Intervention Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-04 Mo‐Yao Tan, Ping Zhang, Ming Gao
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Editorial: Disentangling Early‐Life Antibiotics and Infections as Risk Factors for the Development of Childhood IBD Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-04 Katherine L. Stone, Adam S. Faye
As the global prevalence of inflammatory bowel disease (IBD) is increasing, emphasis has been placed on identifying modifiable risk factors that can aid in prevention [1]. Early-life factors, including antibiotic use and the occurrence of infections, increase the risk of developing IBD [2, 3]. This has been demonstrated in several studies, including a large-scale population-based study in Denmark,
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Editorial: Timely Follow‐Up in Cirrhosis: How Does It Work? Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-04 Nina Kimer, Lise Lotte Gluud
Cirrhosis is a debilitating disease with substantial impact on health and prognosis. As the early stages of cirrhosis are asymptomatic or associated with non-specific symptoms, it was previously often diagnosed late in the disease course, after the development complications [1]. New biomarkers, liver scores and elastography have advanced noninvasive diagnosis, and the incidence and prevalence of cirrhosis
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Editorial: Timely Follow‐Up in Cirrhosis—How Does It Work? Authors' Reply Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-04 Max S. Schechter, Hannes Hagström
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Letter: Analysis of ‘Faecal Biomarkers for Diagnosis and Prediction of Disease Course in Treatment‐Naive Patients With IBD’ Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-04 Yuxiang Chen, Wenjian Hu, Fengfeng Qin
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Letter: Analysis of “Faecal Biomarkers for Diagnosis and Prediction of Disease Course in Treatment‐Naïve Patients With IBD”—Authors' Reply Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-04 Maria Ling Lundström, Maria Lampinen, Marie Carlson, Jonas Halfvarson
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Letter: Assessing the Durability of Treatment Effects: Long‐Term Outcomes of ESWL and ERCP for Pancreatic Duct Stones in Chronic Pancreatitis Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-04 Wei‐Zhen Tang, Bo‐Yuan Deng, Tai‐Hang Liu
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Letter: The Prognostic Role of IGF‐1 in Chronic Liver Disease Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-04 Muhammad Osama, Safiyyah Ubaid, Maryam Ubaid
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Letter: The Prognostic Role of IGF‐1 in Chronic Liver Disease—Authors' Reply Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-11-04 Lukas Hartl, Michael Schwarz, Benedikt Simbrunner, Mathias Jachs, Peter Wolf, David Josef Maria Bauer, Bernhard Scheiner, Lorenz Balcar, Georg Semmler, Benedikt Silvester Hofer, Nina Dominik, Rodrig Marculescu, Michael Trauner, Mattias Mandorfer, Thomas Reiberger
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XBB.1.5-Adapted COVID-19 mRNA Vaccines but Not Infections With Previous Omicron Variants Boost Neutralisation Against the SARS-CoV-2 JN.1 Variant in Patients With Inflammatory Bowel Disease Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-29 Simon Woelfel, Joel Dütschler, Daniel Junker, Marius König, Nicole Graf, Claudia Krieger, Samuel Truniger, Vasileios Oikonomou, Georg Leinenkugel, Seraina Koller, Katline Metzger-Peter, Jacqueline Wyss, Niklas Krupka, Nicola Frei, , Werner C. Albrich, Matthias Friedrich, Jan Hendrik Niess, Nicole Schneiderhan-Marra, Alex Dulovic, Benjamin Misselwitz, Wolfgang Korte, Justus J. Bürgi, Stephan Brand
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Prevalence of Low FIB-4 in MASLD-Related Hepatocellular Carcinoma: A Multicentre Study Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-27 Darren Jun Hao Tan, Nobuharu Tamaki, Beom Kyung Kim, Karn Wijarnpreecha, Majd Bassam Aboona, Claire Faulkner, Charlotte Kench, Shirin Salimi, Abdul-Hamid Sabih, Wen Hui Lim, Pojsakorn Danpanichkul, Benjamin Tay, Yiqing Teh, John Mok, Benjamin Nah, Cheng Han Ng, Mark Muthiah, Anand V. Kulkarni, Sung Won Lee, Ken Liu, Rohit Loomba, Daniel Q. Huang
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Editorial: Decoding ACLF—Sub‐Phenotyping to Advance Precision Medicine in Acute‐On‐Chronic Liver Failure Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-29 Amy Sangam, Banwari Agarwal, Rohit Saha
Patients ‘lumped’ into the syndrome acute-on-chronic liver failure (ACLF) differ on several observable levels: underlying aetiology of cirrhosis, precipitants, number and severity of organ failures (OFs). Despite phenotypic heterogeneity, consensus definitions of ACLF have changed how the condition is understood, recognised and studied. A key unmet need is identifying which elements of ACLF heterogeneity
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Editorial: Decoding ACLF—Sub‐Phenotyping to Advance Precision Medicine in Acute‐on‐Chronic Liver Failure. Authors' Reply Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-29 Pratibha Garg, Nipun Verma, Ajay Duseja
We sincerely appreciate the insightful Editorial by Sangam et al. regarding our study [1, 2]. We echo the call for harmonising definitions and prognostication in acute-on-chronic liver failure (ACLF) [3]. While the debate over definitions continues, the core concept of ACLF—a rapid deterioration due to an acute insult on chronic liver disease, with organ dysfunction and high short-term mortality—remains
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Evaluation of the Effectiveness and Safety of Mesenchymal Stem Cell Treatment in Fistulising Crohn's Disease: An International Real‐Life Retrospective Multicentre Cohort Study Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-29 Péter Bacsur, Daniel Shaham, Zuzana Serclova, Tamás Resál, Bernadett Farkas, Patrícia Sarlós, Pál Miheller, Nitsan Maharshak, Meir Zemel, Ariella Shitrit, Anita Bálint, Anna Fábián, Renáta Bor, Zsófia Bősze, Emese Ivány, Zoltán Szepes, Klaudia Farkas, Illés Tóth, György Lázár, Katerina Vlkova, Aneta Tremerova, Petra Zuskova, Szabolcs Ábrahám, Tamás Molnár
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Validating Simple Modifications to the Rome IV Criteria for the Diagnosis of Irritable Bowel Syndrome in Secondary Care Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-28 Vivek C. Goodoory, Christy Riggott, Mais Khasawneh, Christopher J. Black, Alexander C. Ford
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Letter: Filling the Gaps—Enhancing MASLD Prognosis With Imaging, Diverse Populations and Extended Follow‐Up. Authors' Reply Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-28 Nobuharu Tamaki, Takefumi Kimura, Shun‐Ichi Wakabayashi, Takeji Umemura, Namiki Izumi, Rohit Loomba, Masayuki Kurosaki
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Letter: Filling the Gaps—Enhancing MASLD Prognosis With Imaging, Diverse Populations and Extended Follow‐Up Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-28 Qi‐En Shen, Chengfu Xu
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Editorial: Understanding the Trade‐Offs When Considering Positivity Threshold of Faecal Immunochemical Tests Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-28 Thomas F. Imperiale
The faecal immunochemical test (FIT) is the most used colorectal cancer (CRC) screening test worldwide [1]. FIT is a family of tests, the performance of which varies by brand, positivity threshold and testing interval [2, 3]. Despite myriad studies, the optimal FIT threshold and interval remain elusive. Countries and large health care systems that screen primarily with FIT must decide on the threshold
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aCCI‐HBV‐ACLF: A Novel Predictive Model for Hepatitis B Virus‐Related Acute‐On‐Chronic Liver Failure Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-26 Xinyi Chen, Feiqiong Gao, Qiaoling Pan, Chenjie Huang, Rui Luo, Xiaoqing Lu, Xiaoxiao Chen, Tan Li, Haijun Huang, Jian Wu, Jiong Yu, Lanjuan Li, Hongcui Cao
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Early‐Life Infections, Antibiotics and Later Risk of Childhood and Early Adult‐Onset Inflammatory Bowel Disease: Pooled Analysis of Two Scandinavian Birth Cohorts Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-25 Karl Mårild, Tereza Lerchova, Malin Östensson, Henrik Imberg, Ketil Størdal, Johnny Ludvigsson
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Letter: MASLD in people with HIV exhibits higher fibrosis stage despite lower disease activity than in matched controls Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-25 Junbin Yan, Yunmeng Nie, Shuo Zhang
LINKED CONTENTThis article is linked to Allende et al paper. To view this article, visit https://doi.org/10.1111/apt.18236
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Correction to ‘A Personalised Algorithm Predicting the Risk of Intravenous Corticosteroid Failure in Acute Ulcerative Colitis’ Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-25
Croft A, Okano S, Hartel G, Lord A, Walker G, Tambakis G, et al. A personalised algorithm predicting the risk of intravenous corticosteroid failure in acute ulcerative colitis. Aliment Pharmacol Ther. 2024; 60: 921–933. https://doi.org/10.1111/apt.18190. The units of measurement used to describe C-reactive protein (CRP) concentration in this manuscript were incorrectly reported as mg/mL. This should
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Letter: The Essential Role of Social Workers in Reducing Socioeconomic Disparities in Chronic Liver Disease—Author's Reply Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-24 Eunice Yewon Lee, Linda Henry, Mindie H. Nguyen
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Factors Associated With Abdominal Pain in Patients With Active and Quiescent Ulcerative Colitis: A Multicohort Study Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-24 Tom van Gils, Hans Törnblom, Jóhann P. Hreinsson, Börje Jonefjäll, Hans Strid, Magnus Simrén
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Letter: The Essential Role of Social Workers in Reducing Socioeconomic Disparities in Chronic Liver Disease Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-24 Qiong Yi, GuangYao Wang, ZongXiang Yue
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Issue Information Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-23
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Editorial: The Impact of Socioeconomic and Ethnic Factors on Chronic Liver Disease—Author's Reply Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-23 Eunice Yewon Lee, Linda Henry, Mindie H. Nguyen
LINKED CONTENTThis article is linked to Lee et al papers. To view these articles, visit https://doi.org/10.1111/apt.18242 and https://doi.org/10.1111/apt.18304.
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Editorial: The Impact of Socioeconomic and Ethnic Factors on Chronic Liver Disease Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-23 Wah Loong Chan, Kee Huat Chuah
Chronic liver diseases (CLDs) are a global health concern of significant magnitude, yet their true impact is often underestimated [1]. These diseases contribute to approximately two million deaths each year, accounting for around 4% of all global fatalities [2]. Despite their prevalence, CLDs frequently receive less attention compared to other major health issues. A timely study by Lee et al. which
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Letter: Enhancing Predictive Models for Paediatric Ulcerative Colitis—Addressing Socioeconomic, Environmental and Clinical Factors. Authors' Reply Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-18 Merle Claßen, Benjamin Schiller, Jan Däbritz
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Letter: Enhancing Predictive Models for Paediatric Ulcerative Colitis—Addressing Socioeconomic, Environmental and Clinical Factors Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-18 Aga Luo
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Faecal Volatile Organic Compounds to Detect Colorectal Neoplasia in Lynch Syndrome—A Prospective Longitudinal Multicentre Study Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-18 Elsa L. S. A. van Liere, Dewkoemar Ramsoekh, Emma Daulton, Maya Dakkak, Joris M. van Lingen, Trenton K. Stewart, Sofie Bosch, Beatriz Carvalho, Evelien Dekker, Maarten A. J. M. Jacobs, Jan Jacob Koornstra, Johan P. Kuijvenhoven, Monique E. van Leerdam, Tim G. J. de Meij, Gerrit A. Meijer, Manon C. W. Spaander, James A. Covington, Nanne K. H. de Boer
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Letter: Gut microbiota—An overlooked therapeutic target in the prevention of post-operative recurrence of Crohn's disease Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-17 D. Bogatic, R. V. Bryant
This article is linked to Bak et al paper. To view this article, visit https://doi.org/10.1111/apt.18240.
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Editorial: Advanced glycation end products - a dietary culprit for IBD in the genetically susceptible? Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-17 Fahim Ebrahimi, Anders Forss
This article is linked to Jiang et al paper. To view this article, visit https://doi.org/10.1111/apt.18218
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Editorial: To Stop Or Not To Stop: Is It Still A Question? Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-17 Stephan R. Vavricka, Thomas Greuter
Treatment approaches for inflammatory bowel disease (IBD) have changed considerably within the last two decades. Biological agents and small molecules have dramatically lifted the therapeutic ceiling. The treat-to-target concept is increasingly implemented with the latest STRIDE-II guidelines summarising the key goals as symptomatic response and remission, normalisation of C-reactive protein and decrease
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Editorial: To Stop or Not to Stop, Is It Still a Question? Authors' Reply Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-17 Jeongkuk Seo, Byong Duk Ye
We sincerely thank Vavricka et al. for their thoughtful insights on our study [1, 2]. Their editorial offers a timely and relevant discussion of topics such as mucosal healing, the top-down strategy and treatment de-escalation, all of which represent important shifts in the management of inflammatory bowel disease (IBD) [3-5]. Due to space constraints, we were unable to cover these aspects in sufficient
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Editorial: Enhancing targeted screening of people living with HIV for liver fibrosis Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-17 Shui-Shan Lee, Grace Chung-Yan Lui
This article is linked to Allende et al paper. To view this article, visit https://doi.org/10.1111/apt.18236.
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Letter: Muddle of serum sPD-1 and sPD-L1 levels and association with HBsAg clearance in HBeAg-negative CHB patients on IFN therapy Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-17 Ankur Jindal
This article is linked to Chen et al paper. To view this article, visit https://doi.org/10.1111/apt.18131.
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Letter: Allostatic load—A potential key in the development of inflammatory bowel disease Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-17 Maryam Kharal, Muhammad Hassan Shahbaz, Muhammad Salman Nadeem, Sana Shahbaz
This article is linked to Zhao et al paper. To view this article, visit https://doi.org/10.1111/apt.18217.
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Editorial: Viral hepatitis elimination: Still a big challenge: Care is not only for C Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-17 Nikolaos Papadopoulos, Melanie Deutsch
This article is linked to Vargas-Accarino et al paper. To view this article, visit https://doi.org/10.1111/apt.18227.
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Clinical Trial Design Considerations for Hospitalised Patients With Ulcerative Colitis Flares and Application to Study Hyperbaric Oxygen Therapy in the NIDDK HBOT-UC Consortium Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-15 Parambir S. Dulai, Lauren Balmert Bonner, Charlotte Sadler, Laura E. Raffals, Gursimran Kochhar, Peter Lindholm, Jay C. Buckey, Gary N. Toups, Libeth Rosas, Neeraj Narula, Vipul Jairath, Sailish Honap, Laurent Peyrin-Biroulet, Bruce E. Sands, Stephen B. Hanauer, Denise M. Scholtens, Corey A. Siegel
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Semaglutide 2.4 mg in Participants With Metabolic Dysfunction‐Associated Steatohepatitis: Baseline Characteristics and Design of the Phase 3 ESSENCE Trial Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-16 Philip N. Newsome, Arun J. Sanyal, Kristiane A. Engebretsen, Iris Kliers, Laura Østergaard, Denise Vanni, Elisabetta Bugianesi, Mary E. Rinella, Michael Roden, Vlad Ratziu
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Review article: Optimisation of biologic (monoclonal antibody) therapeutic response in inflammatory bowel disease Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-15 Thanaboon Chaemsupaphan, Rupert W. Leong, Niels Vande Casteele, Cynthia H. Seow
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Review article: Measuring disease severity in inflammatory bowel disease – Beyond treat to target Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-15 Akhilesh Swaminathan, Andrew S. Day, Miles P. Sparrow, Laurent Peyrin‐Biroulet, Corey A. Siegel, Richard B. Gearry
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Review article: Prevention of inflammatory bowel disease—The path forward Aliment. Pharm. Ther. (IF 6.6) Pub Date : 2024-10-15 Sérgio Bronze, Manasi Agrawal, Jean‐Frédéric Colombel, Joana Torres, Ryan C. Ungaro