OBJECTIVES To describe financial toxicity (FT) in patients who have undergone gastrointestinal (GI) surgery and its correlation with patients' emotional (EWB) and social well-being (SWB). BACKGROUND FT describes the financial burden associated with treatment and its impact on patient outcomes. Few prior studies have examined FT in gastrointestinal surgery and its impact on patient quality of life. METHODS Patients who underwent gastrointestinal surgery at our institution were assessed for FT with a validated instrument between Jan 2022 and Jan 2023. EWB and SWB were assessed with a validated instrument. Risk factors for FT were determined using a multivariable model. The correlation between FT and patient EWB and SWB was assessed using Pearson correlation. RESULTS 188 patients were surveyed, the majority had pancreatic resections (n = 90, 47.9%), 59 (31.4%) patients experienced FT. On multivariable analysis, categories associated with increased likelihood of exhibiting financial toxicity included single marital status and not receiving chemotherapy and/or radiation therapy, with odds ratio (95% C.I) of [3.02 (1.07, 8.51), P=.037] and [3.86 (1.3, 11.44), P=.015) respectively. Higher EWB and SWB scores directly correlated with higher FT scores. CONCLUSION Patients undergoing complex gastrointestinal surgery often experience financial toxicity that affects patient reported outcomes. Financial toxicity is associated with identifiable pre-operative factors that can be utilized to screen patients for interventions that may mitigate some of the harmful effects of FT.

中文翻译：

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复杂胃肠道手术中的财务毒性及其与患者报告结果的相关性。


目的 描述接受胃肠道 （GI） 手术的患者的经济毒性 （FT） 及其与患者情绪 （EWB） 和社会福祉 （SWB） 的相关性。背景 FT 描述了与治疗相关的经济负担及其对患者预后的影响。先前很少有研究检查胃肠道手术中的 FT 及其对患者生活质量的影响。方法 在我们机构接受胃肠道手术的患者在 2022 年 1 月至 2023 年 1 月期间使用经过验证的仪器评估 FT。EWB 和 SWB 使用经过验证的工具进行评估。使用多变量模型确定 FT 的危险因素。FT 与患者 EWB 和 SWB 之间的相关性使用 Pearson 相关性进行评估。结果 对 188 例患者进行了调查，其中大多数进行了胰腺切除术 （n = 90， 47.9%），59 例 （31.4%） 患者发生了 FT。在多变量分析中，与表现出经济毒性的可能性增加相关的类别包括单身婚姻状况和未接受化疗和/或放疗，比值比 （95% CI） 分别为 [3.02 （1.07， 8.51）， P=.037] 和 [3.86 （1.3， 11.44）， P=.015）。较高的 EWB 和 SWB 分数与较高的 FT 分数直接相关。结论 接受复杂胃肠道手术的患者经常经历影响患者报告结果的经济毒性。经济毒性与可识别的术前因素有关，这些因素可用于筛选患者可能减轻 FT 某些有害影响的干预措施。