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Acute effects of esketamine on hypoxic ventilatory response, haemodynamics, and brain function in healthy volunteers
British Journal of Anaesthesia ( IF 9.1 ) Pub Date : 2024-11-08 , DOI: 10.1016/j.bja.2024.08.040
Simone C. Jansen, Monique van Velzen, Elise Sarton, Albert Dahan, Marieke Niesters, Rutger van der Schrier

The acute hypoxic ventilatory response is a critical chemoreflex originating at the carotid bodies. This study investigates the impact of low-dose i.v. esketamine on the ventilatory response to 20 min of isocapnic hypoxia to test the hypothesis that esketamine does not affect hypoxic ventilation.

中文翻译:


艾氯胺酮对健康志愿者低氧通气反应、血流动力学和脑功能的急性影响



急性缺氧通气反应是起源于颈动脉体的关键 chemoreflex。本研究调查了低剂量静脉注射艾氯胺酮对 20 分钟等碳酸血症缺氧通气反应的影响,以检验艾氯胺酮不影响低氧通气的假设。
更新日期:2024-11-08
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