ObjectivesTo investigate patient tolerability and safety (using urinary tract infection (UTI) as a proxy measure) following EndoSheath‐assisted flexible cystoscopy (eFC). EndoSheaths are single‐use, disposable sheaths used in FC. They reduce cystoscope turnaround times as complicated, time‐consuming and costly sterilisation is no longer necessary. This reduces patient waiting times as cystoscope idle time, the most common rate limiting step, is reduced.Patients and MethodsAll adult patients undergoing eFC over a 26‐month period at a single institution were evaluated prospectively. Post‐eFC, participants rated discomfort on a visual analogue scale (discomfort 1 = none, 2–4 = mild, 5–7 = moderate, 8–10 = severe). The diagnosis of UTI was broad and based on any one of patient self‐report, positive urine culture or antibiotic prescription within 30 days of eFC. Data were analysed using chi‐squared testing (P < 0.05, two‐tailed).ResultsOf the 1091 eFCs analysed, 33.2% and 48.2% of were ranked as causing no or mild discomfort, respectively, with just 3.1% ranked severe. Discomfort was greater in younger participants but similar between sexes. Overall, post‐eFC UTI incidence was 13.3%, with rates higher in females (18.1%) than males (11.2%). Participants aged ≥65 years reported a higher UTI rate (15.4%) than those aged <65 years (8.8%). No participants developed urosepsis.ConclusionThis large, prospective, unselected, real‐world study reports that eFC is well tolerated. UTI was higher in females than males, and in those aged ≥65 years, in line with other studies using the same broad based diagnostic criteria for UTI. The conclusion is that eFC is both well tolerated and safe.

中文翻译：

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内鞘在软式膀胱镜检查中的应用：>1000 例病例的前瞻性评估


目的探讨内鞘辅助可弯曲膀胱镜检查 （eFC） 后患者的耐受性和安全性 （使用尿路感染 （UTI） 作为替代指标）。EndoSheaths 是 FC 中使用的一次性护套。它们减少了膀胱镜的周转时间，因为不再需要复杂、耗时和昂贵的消毒。这减少了患者的等待时间，因为膀胱镜空闲时间（最常见的速率限制步骤）减少了。患者和方法对在单个机构接受 eFC 的 26 个月内接受 eFC 的所有成年患者进行了前瞻性评估。eFC 后，参与者根据视觉模拟量表对不适进行评分（不适 1 = 无，2-4 = 轻度，5-7 = 中度，8-10 = 严重）。UTI 的诊断范围很广，基于患者自我报告、尿培养阳性或 eFC 后 30 天内开具抗生素处方中的任何一项。使用卡方检验分析数据 （P < 0.05，双尾）。结果在分析的 1091 个 eFC 中，分别有 33.2% 和 48.2% 被评为没有或轻微不适，只有 3.1% 被评为严重。年轻参与者的不适感更大，但性别之间的不适感相似。总体而言，eFC 后 UTI 发生率为 13.3%，女性 （18.1%） 高于男性 （11.2%）。≥65 岁的参与者报告的 UTI 发生率 （15.4%） 高于 <65 岁的参与者 （8.8%）。没有受试者出现尿脓毒症。结论这项大型、前瞻性、未经选择的真实世界研究报告称，eFC 耐受性良好。女性的 UTI 高于男性，年龄≥ 65 岁的人群中，与其他使用相同基础广泛的 UTI 诊断标准的研究一致。结论是 eFC 耐受性良好且安全。