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Tug of war between phosphatase and kinase during sleep Cell Res. (IF 28.1) Pub Date : 2024-12-20 Niels Niethard, Jan Born
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Correction: Sanofi-Cell Research outstanding paper award of 2023 Cell Res. (IF 28.1) Pub Date : 2024-12-12
Correction to: Cell Research https://doi.org/10.1038/s41422-024-01056-6, published online 26 November 2024
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Photoactivated SOPP3 enables APEX2-mediated proximity labeling with high spatio-temporal resolution in live cells Cell Res. (IF 28.1) Pub Date : 2024-12-10 Dajun Qu, Yaxin Li, Qian Liu, Biao Cao, Mengye Cao, Xiaoxi Lin, Chengxing Shen, Peng Zou, Hu Zhou, Wenjuan Zhang, Weijun Pan
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Triaptosis: an endosome-dependent cell death modality Cell Res. (IF 28.1) Pub Date : 2024-12-06 Daolin Tang, Rui Kang, Guido Kroemer
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Encoding immune responses: the moonlighting function of alanyl-tRNA synthetase Cell Res. (IF 28.1) Pub Date : 2024-11-28 Pin Wang, Xiaoyu Hu
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Sanofi-Cell Research outstanding paper award of 2023 Cell Res. (IF 28.1) Pub Date : 2024-11-26
We are pleased to announce the recipients of the 2023 Sanofi-Cell Research Outstanding Research Article Award: Drs. Tianqing Li, Zongyong Ai and Weizhi Ji for their paper entitled “Dissecting peri-implantation development using cultured human embryos and embryo-like assembloids”;1 Drs. Qiao Wu, Wei-jia Wang and Xuehui Hong for their paper entitled “Mannose antagonizes GSDME-mediated pyroptosis through
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Stressing out the intestinal microbiota via a brain-neuroglandular circuit Cell Res. (IF 28.1) Pub Date : 2024-11-26 Wen Zhang, David Artis
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A GSDMD agonist boosts specific antitumor immunity Cell Res. (IF 28.1) Pub Date : 2024-11-13 Yingying Zhang, Jiahuai Han
The beneficial role of gasdermin activation and pyroptosis induction in antitumor immunity has been implicated by several studies; however, the question of how to specifically and efficiently activate cancer cell death while minimizing toxicity to host cells remains unsolved. In a recent paper published in Cell, Wu and Lieberman groups identified a GSDMD agonist that can induce low-level pyroptosis
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Structure and genome editing activity of the novel CRISPR-Cas12o1 effector Cell Res. (IF 28.1) Pub Date : 2024-11-08 Zhiqiang Duan, Xi Zhang, Jun-Tao Zhang, Xingkun Ji, Ruiheng Liu, Ying Chen, Shanshan Li, Nannan Jia, Huizhi Gao, Yu Xin, Ning Jia, Jian-Kang Zhu
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A cross-species foundation model for single cells Cell Res. (IF 28.1) Pub Date : 2024-10-31 Korbinian Traeuble, Matthias Heinig
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Structure basis of ligand recognition and activation of GPR55 Cell Res. (IF 28.1) Pub Date : 2024-10-31 Hao Chang, Xiaoting Li, Ling Shen, Xuanrui Ge, Shuming Hao, Lijie Wu, Shenhui Liu, Junlin Liu, Vadim Cherezov, Tian Hua
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Structural insight into GPR55 ligand recognition and G-protein coupling Cell Res. (IF 28.1) Pub Date : 2024-10-31 Ruixue Xia, Qingning Yuan, Na Wang, Li Hou, Junpei Abe, Jing Song, Yukishige Ito, H. Eric Xu, Yuanzheng He
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The mechanism of bacterial defense system DdmDE from Lactobacillus casei Cell Res. (IF 28.1) Pub Date : 2024-10-24 Pingping Huang, Purui Yan, Lijie Guo, Wenying Fei, Zhaoxing Li, Jingxian Liu, Jianping Kong, Yue Yao, Meiling Lu, Yibei Xiao, Meirong Chen
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Nucleophagy repairs toxic DNA lesions Cell Res. (IF 28.1) Pub Date : 2024-10-22 Ines Tomaskovic, Cristian Prieto-Garcia, Ivan Dikic
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Population-wide DNA methylation polymorphisms at single-nucleotide resolution in 207 cotton accessions reveal epigenomic contributions to complex traits Cell Res. (IF 28.1) Pub Date : 2024-10-17 Ting Zhao, Xueying Guan, Yan Hu, Ziqian Zhang, Han Yang, Xiaowen Shi, Jin Han, Huan Mei, Luyao Wang, Lei Shao, Hongyu Wu, Qianqian Chen, Yongyan Zhao, Jiaying Pan, Yupeng Hao, Zeyu Dong, Xuan Long, Qian Deng, Shengjun Zhao, Mengke Zhang, Yumeng Zhu, Xiaowei Ma, Zequan Chen, Yayuan Deng, Zhanfeng Si, Xin Li, Tianzhen Zhang, Fei Gu, Xiaofeng Gu, Lei Fang
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Immunity hubs orchestrating antiviral defense Cell Res. (IF 28.1) Pub Date : 2024-10-16 Linnan Zhu, Zemin Zhang
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Fine-tuning protein hunger: sex- and mating-dependent setpoint control Cell Res. (IF 28.1) Pub Date : 2024-10-14 Yangkyun Oh, Won-Jae Lee
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Fueling metabolic adaptation: lysosomal AMPK ignites glutaminolysis Cell Res. (IF 28.1) Pub Date : 2024-10-14 Benoit Viollet, Bruno Guigas
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Knowing when to stop: MICL self-regulates neutrophil NETosis Cell Res. (IF 28.1) Pub Date : 2024-10-14 Hanjoo Brian Shim, Justin François Deniset, Paul Kubes
In a recent study published in Nature, Malamud et al. identified how neutrophil MICL recognizes neutrophil extracellular traps (NETs). This recognition suppresses further neutrophil activation and NET production, thereby preventing a vicious cycle of inflammation.
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GeneCompass: deciphering universal gene regulatory mechanisms with a knowledge-informed cross-species foundation model Cell Res. (IF 28.1) Pub Date : 2024-10-08 Xiaodong Yang, Guole Liu, Guihai Feng, Dechao Bu, Pengfei Wang, Jie Jiang, Shubai Chen, Qinmeng Yang, Hefan Miao, Yiyang Zhang, Zhenpeng Man, Zhongming Liang, Zichen Wang, Yaning Li, Zheng Li, Yana Liu, Yao Tian, Wenhao Liu, Cong Li, Ao Li, Jingxi Dong, Zhilong Hu, Chen Fang, Lina Cui, Zixu Deng, Haiping Jiang, Wentao Cui, Jiahao Zhang, Zhaohui Yang, Handong Li, Xingjian He, Liqun Zhong, Jiaheng Zhou
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Feeling the danger: local wound signaling in plants Cell Res. (IF 28.1) Pub Date : 2024-10-01 Lukas Hoermayer, Jiří Friml
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PCDH10 is a neuronal receptor for western equine encephalitis virus Cell Res. (IF 28.1) Pub Date : 2024-09-20 Yan Yang, Li-Xin Zhao, Zhen-Qi Li, Su-Yun Wang, Zhi-Sheng Xu, Yan-Yi Wang
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AMPK-PDZD8-GLS1 axis mediates calorie restriction-induced lifespan extension Cell Res. (IF 28.1) Pub Date : 2024-09-19 Mengqi Li, Yu Wang, Xiaoyan Wei, Wei-Feng Cai, Yan-Hui Liu, Jianfeng Wu, Yan Chen, Jinye Xiong, Li-Feng Cui, Mingxia Zhu, Cixiong Zhang, Liyun Lin, Yong Yu, Hai-Long Piao, Sheng-Cai Lin, Chen-Song Zhang
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α-Synuclein amyloid fibril directly binds to LC3B and suppresses SQSTM1/p62-mediated selective autophagy Cell Res. (IF 28.1) Pub Date : 2024-09-19 Qianhui Xu, Huilan Wang, Ruonan Yang, Youqi Tao, Ziying Wang, Shengnan Zhang, Bo Sun, Dan Li, Boxun Lu, Cong Liu
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Author Correction: Targeting pro-inflammatory T cells as a novel therapeutic approach to potentially resolve atherosclerosis in humans Cell Res. (IF 28.1) Pub Date : 2024-09-18 Lin Fan, Junwei Liu, Wei Hu, Zexin Chen, Jie Lan, Tongtong Zhang, Yang Zhang, Xianpeng Wu, Zhiwei Zhong, Danyang Zhang, Jinlong Zhang, Rui Qin, Hui Chen, Yunfeng Zong, Jianmin Zhang, Bing Chen, Jun Jiang, Jifang Cheng, Jingyi Zhou, Zhiwei Gao, Zhenjie Liu, Ying Chai, Junqiang Fan, Pin Wu, Yinxuan Chen, Yuefeng Zhu, Kai Wang, Ying Yuan, Pintong Huang, Ying Zhang, Huiqin Feng, Kaichen Song, Xun Zeng
Correction to: Cell Research https://doi.org/10.1038/s41422-024-00945-0, published online 15 March 2024
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Lysine methylation steps into another step of the central dogma Cell Res. (IF 28.1) Pub Date : 2024-09-17 Zuodong Zhao, Bing Zhu
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tRNA repair: the key to thermo-sensitive male sterility in rice Cell Res. (IF 28.1) Pub Date : 2024-09-16 Nai-Qian Dong, Hong-Xuan Lin
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The 1% gift to humanity: The Human Genome Project II Cell Res. (IF 28.1) Pub Date : 2024-09-11 Weibin Liu, Yan Li, George P. Patrinos, Shuhua Xu, Meow-Keong Thong, Zhengming Chen, Francis P. Crawley, Liming Li, Perihan Elif Ekmekci, Radoje Drmanac, Weiyang Cheong, Robert Benamouzig, Quan Nguyen, Pavel Volchkov, Juergen K. V. Reichardt, Piero Carninci, Partha Majumder, Xin Jin, George Church, Jian Wang, Xun Xu
Upon announcing the completion of the Human Genome Project (HGP) in 2003, scientific leaders envisaged the transformative promise of the human genome for health and society.1 They anticipated genomics breakthroughs that could touch all of humanity and empower people to have longer healthier lives, ultimately creating a more prosperous society that also wields the human genome responsibly. Two decades
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Reducing off-target effects of DdCBEs by reversing amino acid charge near DNA interaction sites Cell Res. (IF 28.1) Pub Date : 2024-09-10 Long Xie, Yaqi Cao, Di Li, Mengxue Ma, Danrong Jiao, Hu Feng, Zhenrui Zuo, Erwei Zuo
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Impaired 2′,3′-cyclic phosphate tRNA repair causes thermo-sensitive genic male sterility in rice Cell Res. (IF 28.1) Pub Date : 2024-09-09 Bin Yan, Chunyan Liu, Jing Sun, Yang Mao, Can Zhou, Ji Li, Wei Liu, Shengdong Li, Wei Yan, Chenjian Fu, Peng Qin, Xingxue Fu, Xinghui Zhao, Xianwei Song, Jiawei Nie, Feng Gao, Yuanzhu Yang, Yuhang Chen, Xiaofeng Cao
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Transport mechanism and structural pharmacology of human urate transporter URAT1 Cell Res. (IF 28.1) Pub Date : 2024-09-09 Yaxin Dai, Chia-Hsueh Lee
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Mechanistic insights of substrate transport and inhibitor binding revealed by high-resolution structures of human norepinephrine transporter Cell Res. (IF 28.1) Pub Date : 2024-09-02 Ailong Song, Xudong Wu
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PDK1 neddylation by Smurf1 drives Akt activation Cell Res. (IF 28.1) Pub Date : 2024-08-29 Rajesh Kumar Manne, Rajni Kant, Hui-Kuan Lin
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Illuminating nucleosome interactions Cell Res. (IF 28.1) Pub Date : 2024-08-27 Silvija Bilokapic, Mario Halic
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Preservation of a youthful path to evergreen platelets? Cell Res. (IF 28.1) Pub Date : 2024-08-23 Sten Eirik W. Jacobsen
The enhanced myeloid lineage bias of old hematopoietic stem cells (HSCs) has been implicated to underpin the compromised immunity observed upon aging. In a recent paper in Cell, Poscablo and coworkers now present experimental support for also the dysregulated function of platelets seen during aging, emanating at the aged HSC level; they identified an aging- and platelet-specific differentiation pathway
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Structural basis of the bacterial flagellar motor rotational switching Cell Res. (IF 28.1) Pub Date : 2024-08-23 Jiaxing Tan, Ling Zhang, Xingtong Zhou, Siyu Han, Yan Zhou, Yongqun Zhu
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Stroke-induced trained immunity spells bad news for the heart Cell Res. (IF 28.1) Pub Date : 2024-08-20 George Hajishengallis, Triantafyllos Chavakis
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Accurate de novo design of heterochiral protein–protein interactions Cell Res. (IF 28.1) Pub Date : 2024-08-14 Ke Sun, Sicong Li, Bowen Zheng, Yanlei Zhu, Tongyue Wang, Mingfu Liang, Yue Yao, Kairan Zhang, Jizhong Zhang, Hongyong Li, Dongyang Han, Jishen Zheng, Brian Coventry, Longxing Cao, David Baker, Lei Liu, Peilong Lu
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NLRC5 PANoptosome: Aquaman of the Dead Sea Cell Res. (IF 28.1) Pub Date : 2024-08-07 Poonam S. Jadhav, Shreya Mahajan, Si Ming Man
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SMYD5 is a ribosomal methyltransferase that catalyzes RPL40 lysine methylation to enhance translation output and promote hepatocellular carcinoma Cell Res. (IF 28.1) Pub Date : 2024-08-05 Bisi Miao, Ling Ge, Chenxi He, Xinghao Wang, Jibo Wu, Xiang Li, Kun Chen, Jinkai Wan, Shenghui Xing, Lingnan Ren, Zhennan Shi, Shengnan Liu, Yajun Hu, Jiajia Chen, Yanyan Yu, Lijian Feng, Natasha M. Flores, Zhihui Liang, Xinyi Xu, Ruoxin Wang, Jian Zhou, Jia Fan, Bin Xiang, En Li, Yuanhui Mao, Jingdong Cheng, Kehao Zhao, Pawel K. Mazur, Jiabin Cai, Fei Lan
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Structural basis for linker histone H5–nucleosome binding and chromatin fiber compaction Cell Res. (IF 28.1) Pub Date : 2024-08-05 Wenyan Li, Jie Hu, Feng Song, Juan Yu, Xin Peng, Shuming Zhang, Lin Wang, Mingli Hu, Jia-Cheng Liu, Yu Wei, Xue Xiao, Yan Li, Dongyu Li, Hui Wang, Bing-Rui Zhou, Linchang Dai, Zongjun Mou, Min Zhou, Haonan Zhang, Zheng Zhou, Huidong Zhang, Yawen Bai, Jin-Qiu Zhou, Wei Li, Guohong Li, Ping Zhu
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Synergizing sequence and structure representations to predict protein variants Cell Res. (IF 28.1) Pub Date : 2024-08-01 Tong Chen, Pranam Chatterjee
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Deciphering the role of immune system in the obesity–cancer relationship Cell Res. (IF 28.1) Pub Date : 2024-07-30 Camille Blériot, Gerasimos Anagnostopoulos, Florent Ginhoux
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Author Correction: Structural and functional evidence that GPR30 is not a direct estrogen receptor Cell Res. (IF 28.1) Pub Date : 2024-07-29 Heng Liu, Shimeng Guo, Antao Dai, Peiyu Xu, Xin Li, Sijie Huang, Xinheng He, Kai Wu, Xinyue Zhang, Dehua Yang, Xin Xie, H. Eric Xu
Correction to: Cell Research https://doi.org/10.1038/s41422-024-00963-y, published online 14 May 2024
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Yin and Yang of innate immune cell death Cell Res. (IF 28.1) Pub Date : 2024-07-26 Yaqiu Wang, Thirumala-Devi Kanneganti
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Can dental problems be indicative of clonal hematopoiesis? Cell Res. (IF 28.1) Pub Date : 2024-07-25 Soichi Sano, Kenneth Walsh
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Coding, or non-coding, that is the question Cell Res. (IF 28.1) Pub Date : 2024-07-25 Laura Poliseno, Martina Lanza, Pier Paolo Pandolfi
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Author Correction: Discovery and structural mechanism of DNA endonucleases guided by RAGATH-18-derived RNAs Cell Res. (IF 28.1) Pub Date : 2024-07-23 Kuan Ren, Fengxia Zhou, Fan Zhang, Mingyu Yin, Yuwei Zhu, Shouyu Wang, Yan Chen, Tengjin Huang, Zixuan Wu, Jiale He, Anqi Zhang, Changyou Guo, Zhiwei Huang
Correction to: Cell Research https://doi.org/10.1038/s41422-024-00952-1, published online 04 April 2024
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Rejuvenating immunity through a balancing stem cell act Cell Res. (IF 28.1) Pub Date : 2024-07-23 Sten Eirik W. Jacobsen
An alteration in the lineage bias of aged hematopoietic stem cells (HSCs) has been implicated in the reduced immunity observed upon aging. Ross and colleagues now provide direct support for this hypothesis, demonstrating that a selective depletion of myeloid-biased HSCs in aged mice is accompanied by improvement in several parameters of immunity, uncovering a possible novel therapeutic avenue for counteracting
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Deletion of V483 in the spike confers evolutionary advantage on SARS-CoV-2 for human adaptation and host-range expansion after a prolonged pandemic Cell Res. (IF 28.1) Pub Date : 2024-07-19 Can Yue, Shuo Liu, Bo Meng, Kaiyue Fan, Sijie Yang, Pan Liu, Qianhui Zhu, Xin Mao, Yuanling Yu, Fei Shao, Peng Wang, Youchun Wang, Ravindra Kumar Gupta, Yunlong Cao, Xiangxi Wang
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Painful memories boost protective immunity Cell Res. (IF 28.1) Pub Date : 2024-07-18 Tri Giang Phan, Elissa K. Deenick
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Novel insight into atrioventricular node conduction Cell Res. (IF 28.1) Pub Date : 2024-07-16 Lu Ren, Joseph C. Wu
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Body–brain axis: orchestrating immune responses Cell Res. (IF 28.1) Pub Date : 2024-07-16 Leon Hosang, Alexander Flügel, Francesca Odoardi
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Structural basis of tethered agonism and G protein coupling of protease-activated receptors Cell Res. (IF 28.1) Pub Date : 2024-07-12 Jia Guo, Yun-Li Zhou, Yixin Yang, Shimeng Guo, Erli You, Xin Xie, Yi Jiang, Chunyou Mao, H. Eric Xu, Yan Zhang
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Perenniality: the tale of three MADS-box genes Cell Res. (IF 28.1) Pub Date : 2024-07-11 Zheng Li, Ruichen Ma, Rishikesh P. Bhalerao
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Bitter taste receptor TAS2R14 activation and G protein assembly by an intracellular agonist Cell Res. (IF 28.1) Pub Date : 2024-07-05 Lele Tao, Dongxue Wang, Qingning Yuan, Fenghui Zhao, Yu Zhang, Tianyuan Du, Shiyi Shen, H. Eric Xu, Yi Li, Dehua Yang, Jia Duan
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Zero-shot prediction of mutation effects with multimodal deep representation learning guides protein engineering Cell Res. (IF 28.1) Pub Date : 2024-07-05 Peng Cheng, Cong Mao, Jin Tang, Sen Yang, Yu Cheng, Wuke Wang, Qiuxi Gu, Wei Han, Hao Chen, Sihan Li, Yaofeng Chen, Jianglin Zhou, Wuju Li, Aimin Pan, Suwen Zhao, Xingxu Huang, Shiqiang Zhu, Jun Zhang, Wenjie Shu, Shengqi Wang
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Molecular insights into the inhibition of proton-activated chloride channel by transfer RNA Cell Res. (IF 28.1) Pub Date : 2024-06-28 Pengliang Chi, Xiang Wang, Jialu Li, Hui Yang, Kaiju Li, Yuqi Zhang, Shiyi Lin, Leiye Yu, Shiqi Liu, Lu Chen, Ruobing Ren, Jianping Wu, Zhuo Huang, Jia Geng, Dong Deng
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Localized, highly efficient secretion of signaling proteins by migrasomes Cell Res. (IF 28.1) Pub Date : 2024-06-25 Haifeng Jiao, Xiaopeng Li, Ying Li, Yuting Guo, Xiaoyu Hu, Takami Sho, Yiqun Luo, Jinyu Wang, Huizhen Cao, Wanqing Du, Dong Li, Li Yu