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Stressing out the intestinal microbiota via a brain-neuroglandular circuit
Cell Research ( IF 28.1 ) Pub Date : 2024-11-26 , DOI: 10.1038/s41422-024-01047-7 Wen Zhang, David Artis
中文翻译:
通过脑神经腺回路对肠道微生物群施加压力
更新日期:2024-11-26
Cell Research ( IF 28.1 ) Pub Date : 2024-11-26 , DOI: 10.1038/s41422-024-01047-7 Wen Zhang, David Artis
A new study published in Cell identifies a stress-sensitive brain-neuroglandular circuit that regulates the intestinal microbiota and systemic host immunity. Chronic stress inhibits the duodenal gland activity, which drives intestinal dysbiosis and impaired host immunity to pathogens.
中文翻译:
通过脑神经腺回路对肠道微生物群施加压力
发表在《细胞》上的一项新研究确定了一种对压力敏感的脑神经腺回路,可调节肠道微生物群和全身宿主免疫。慢性压力会抑制十二指肠腺活动,从而驱动肠道菌群失调和宿主对病原体的免疫力受损。