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Cell Death and Differentiation
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Polyol pathway-generated fructose is indispensable for growth and survival of non-small cell lung cancer Cell Death Differ. (IF 13.7) Pub Date : 2024-11-20 Annemarie Schwab, Mohammad Aarif Siddiqui, Vignesh Ramesh, Paradesi Naidu Gollavilli, Adriana Martinez Turtos, Sarah Søgaard Møller, Luisa Pinna, Jesper F. Havelund, Anne Mette A. Rømer, Pelin Gülizar Ersan, Beatrice Parma, Sabine Marschall, Katja Dettmer, Mohammed Alhusayan, Pietro Bertoglio, Giulia Querzoli, Dirk Mielenz, Ozgur Sahin, Nils J. Færgeman, Irfan A. Asangani, Paolo Ceppi
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KBTBD2 controls bone development by regulating IGF-1 signaling during osteoblast differentiation Cell Death Differ. (IF 13.7) Pub Date : 2024-11-19 Yu Xun, Yiao Jiang, Aysha Khalid, Zeru Tian, Jonathan Rios, Zhao Zhang
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ACBP/DBI neutralization for the experimental treatment of fatty liver disease Cell Death Differ. (IF 13.7) Pub Date : 2024-11-16 Omar Motiño, Flavia Lambertucci, Adrien Joseph, Sylvère Durand, Gerasimos Anagnostopoulos, Sijing Li, Vincent Carbonnier, Uxía Nogueira-Recalde, Léa Montégut, Hui Chen, Fanny Aprahamian, Nitharsshini Nirmalathasan, Maria Chiara Maiuri, Federico Pietrocola, Dominique Valla, Cédric Laouénan, Jean-François Gautier, Laurent Castera, Isabelle Martins, Guido Kroemer
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AKAP1/PKA-mediated GRP75 phosphorylation at mitochondria-associated endoplasmic reticulum membranes protects cancer cells against ferroptosis Cell Death Differ. (IF 13.7) Pub Date : 2024-11-13 Hao Liu, Shanliang Zheng, Guixue Hou, Junren Dai, Yanan Zhao, Fan Yang, Zhiyuan Xiang, Wenxin Zhang, Xingwen Wang, Yafan Gong, Li Li, Ning Zhang, Ying Hu
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Physiological and pathological roles of the transcriptional kinases CDK12 and CDK13 in the central nervous system Cell Death Differ. (IF 13.7) Pub Date : 2024-11-12 Consuelo Pitolli, Alberto Marini, Claudio Sette, Vittoria Pagliarini
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Integrin β6/Annexin A2 axis triggers autophagy to orchestrate hepatocellular carcinoma radioresistance Cell Death Differ. (IF 13.7) Pub Date : 2024-11-12 Ying Gao, Guangyan Wei, Hua Yu, Shuping Li, Yuhao Tang, Xin Yue, Yong Chen, Meixiao Zhan, Jian Wu
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hnRNPA2B1 deacetylation by SIRT6 restrains local transcription and safeguards genome stability Cell Death Differ. (IF 13.7) Pub Date : 2024-11-07 Feng Chen, Wenchao Xu, Ming Tang, Yuan Tian, Yuxin Shu, Xingkai He, Linmin Zhou, Qi Liu, Qian Zhu, Xiaopeng Lu, Jun Zhang, Wei-Guo Zhu
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Correction: STAT3 dictates β-cell apoptosis by modulating PTEN in streptozocin-induced hyperglycemia Cell Death Differ. (IF 13.7) Pub Date : 2024-11-07 Qinjie Weng, Mengting Zhao, Jiahuan Zheng, Lijun Yang, Zijie Xu, Zhikang Zhang, Jincheng Wang, Jiajia Wang, Bo Yang, Q. Richard Lu, Meidan Ying, Qiaojun He
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Localized release of muscle-generated BDNF regulates the initial formation of postsynaptic apparatus at neuromuscular synapses Cell Death Differ. (IF 13.7) Pub Date : 2024-11-07 Jinkai Zhang, Hiu-Lam Rachel Kwan, Chi Bun Chan, Chi Wai Lee
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Tufm lactylation regulates neuronal apoptosis by modulating mitophagy in traumatic brain injury Cell Death Differ. (IF 13.7) Pub Date : 2024-11-05 Weiji Weng, Zhenghui He, Zixuan Ma, Jialin Huang, Yuhan Han, Qiyuan Feng, Wenlan Qi, Yidong Peng, Jiangchang Wang, Jiacheng Gu, Wenye Wang, Yong Lin, Gan Jiang, Jiyao Jiang, Junfeng Feng
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The AKR1C1–CYP1B1–cAMP signaling axis controls tumorigenicity and ferroptosis susceptibility of extrahepatic cholangiocarcinoma Cell Death Differ. (IF 13.7) Pub Date : 2024-10-30 Chang Liu, Cheng Zhang, Hongkun Wu, Zhibin Zhao, Zhenhua Wang, Xiaomin Zhang, Jieli Yang, Wenlong Yu, Zhexiong Lian, Minghui Gao, Lin Zhou
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METTL3 confers oxaliplatin resistance through the activation of G6PD-enhanced pentose phosphate pathway in hepatocellular carcinoma Cell Death Differ. (IF 13.7) Pub Date : 2024-10-29 Xiaohan Jin, Yongrui Lv, Fengjie Bie, Jinling Duan, Chao Ma, Miaomiao Dai, Jiewei Chen, Lianghe Lu, Shuidan Xu, Jie Zhou, Si Li, Jiong Bi, Fengwei Wang, Dan Xie, Muyan Cai
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Apoptosis signaling is activated as a transient pulse in neurons Cell Death Differ. (IF 13.7) Pub Date : 2024-10-26 Keeley L. Spiess, Matthew J. Geden, Selena E. Romero, Emilie Hollville, Elizabeth S. Hammond, Rachel L. Patterson, Quintin B. Girardi, Mohanish Deshmukh
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RIP1 inhibition protects retinal ganglion cells in glaucoma models of ocular injury Cell Death Differ. (IF 13.7) Pub Date : 2024-10-24 Bo Kyoung Kim, Tatiana Goncharov, Sébastien A. Archaimbault, Filip Roudnicky, Joshua D. Webster, Peter D. Westenskow, Domagoj Vucic
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TP53: the unluckiest of genes? Cell Death Differ. (IF 13.7) Pub Date : 2024-10-23 Andreas C. Joerger, Thorsten Stiewe, Thierry Soussi
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Oncometabolites at the crossroads of genetic, epigenetic and ecological alterations in cancer Cell Death Differ. (IF 13.7) Pub Date : 2024-10-23 Letizia Lanzetti
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Myeloid Mir34a suppresses colitis-associated colon cancer: characterization of mediators by single-cell RNA sequencing Cell Death Differ. (IF 13.7) Pub Date : 2024-10-18 Janine König, Matjaz Rokavec, Meryem Gülfem Öner-Ziegler, Ye Fei, Heiko Hermeking
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SOX4 facilitates brown fat development and maintenance through EBF2-mediated thermogenic gene program in mice Cell Death Differ. (IF 13.7) Pub Date : 2024-10-15 Shuai Wang, Ting He, Ya Luo, Kexin Ren, Huanming Shen, Lingfeng Hou, Yixin Wei, Tong Fu, Wenlong Xie, Peng Wang, Jie Hu, Yu Zhu, Zhengrong Huang, Qiyuan Li, Weihua Li, Huiling Guo, Boan Li
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Inhibition of BAK-mediated apoptosis by the BH3-only protein BNIP5 Cell Death Differ. (IF 13.7) Pub Date : 2024-10-15 Sebastian Rühl, Zhenrui Li, Shagun Srivastava, Luigi Mari, Clifford S. Guy, Mao Yang, Tudor Moldoveanu, Douglas R. Green
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AKR1B1-dependent fructose metabolism enhances malignancy of cancer cells Cell Death Differ. (IF 13.7) Pub Date : 2024-10-15 Qing Zhao, Bing Han, Lu Wang, Jia Wu, Siliang Wang, Zhenxing Ren, Shouli Wang, Haining Yang, Michele Carbone, Changsheng Dong, Gerry Melino, Wen-Lian Chen, Wei Jia
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Exploring fructose metabolism as a potential therapeutic approach for pancreatic cancer Cell Death Differ. (IF 13.7) Pub Date : 2024-10-15 Chengqiang Wang, Lu Wang, Qing Zhao, Jiao Ma, Yitao Li, Junliang Kuang, Xintong Yang, Huichang Bi, Aiping Lu, Kenneth C. P. Cheung, Gerry Melino, Wei Jia
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127aa encoded by circSpdyA promotes FA synthesis and NK cell repression in breast cancers Cell Death Differ. (IF 13.7) Pub Date : 2024-10-14 Xinya Gao, Zicheng Sun, Xin Liu, Jiayue Luo, Xiaoli Liang, Huijin Wang, Junyi Zhou, Ciqiu Yang, Tiantian Wang, Jie Li
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SLAMF7 (CD319) on activated CD8+ T cells transduces environmental cues to initiate cytotoxic effector cell responses Cell Death Differ. (IF 13.7) Pub Date : 2024-10-10 Holger Lingel, Laura Fischer, Sven Remstedt, Benno Kuropka, Lars Philipsen, Irina Han, Jan-Erik Sander, Christian Freund, Aditya Arra, Monika C. Brunner-Weinzierl
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Activating the NFE2L1-ubiquitin-proteasome system by DDI2 protects from ferroptosis Cell Death Differ. (IF 13.7) Pub Date : 2024-10-09 Anahita Ofoghi, Stefan Kotschi, Imke L. Lemmer, Daniel T. Haas, Nienke Willemsen, Batoul Bayer, Anna S. Jung, Sophie Möller, Stefanie Haberecht-Müller, Elke Krüger, Natalie Krahmer, Alexander Bartelt
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A novel glucose sensor fuelling cancer growth Cell Death Differ. (IF 13.7) Pub Date : 2024-10-08 Luisa Ricci, Simone Cardaci
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HKDC1 functions as a glucose sensor and promotes metabolic adaptation and cancer growth via interaction with PHB2 Cell Death Differ. (IF 13.7) Pub Date : 2024-10-07 Panpan Liu, Yao Luo, Hongyu Wu, Yi Han, Shoujie Wang, Rui Liu, Shijun Wen, Peng Huang
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Fructose: the sweet(er) side of the Warburg effect Cell Death Differ. (IF 13.7) Pub Date : 2024-10-05 Christian Frezza
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DNA damage-inducible transcript 3 positively regulates RIPK1-mediated necroptosis Cell Death Differ. (IF 13.7) Pub Date : 2024-10-03 Rui Ni, Ting Cao, Xiaoyun Ji, Angel Peng, Zhuxu Zhang, Guo-Chang Fan, Peter Stathopulos, Subrata Chakrabarti, Zhaoliang Su, Tianqing Peng
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Integrated stress response plasticity governs normal cell adaptation to chronic stress via the PP2A-TFE3-ATF4 pathway Cell Death Differ. (IF 13.7) Pub Date : 2024-09-30 Rita A. Avelar, Riya Gupta, Grace Carvette, Felipe da Veiga Leprevost, Medhasri Jasti, Jose Colina, Jessica Teitel, Alexey I. Nesvizhskii, Caitlin M. O’Connor, Maria Hatzoglou, Shirish Shenolikar, Peter Arvan, Goutham Narla, Analisa DiFeo
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Neuronal LAMP2A-mediated reduction of adenylyl cyclases induces acute neurodegenerative responses and neuroinflammation after ischemic stroke Cell Death Differ. (IF 13.7) Pub Date : 2024-09-28 Dingfang Shi, Yunhao Bai, Ruiling Long, Jing Xia, Wenxuan Xu, Dongshen Qin, Xuejun Yang, Ming Ding, Xiao-Yu Hou
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The role(s) of NF-Y in development and differentiation Cell Death Differ. (IF 13.7) Pub Date : 2024-09-26 Diletta Dolfini, Carol Imbriano, Roberto Mantovani
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NF-κB regulated expression of A20 controls IKK dependent repression of RIPK1 induced cell death in activated T cells Cell Death Differ. (IF 13.7) Pub Date : 2024-09-26 By Scott Layzell, Alessandro Barbarulo, Geert van Loo, Rudi Beyaert, Benedict Seddon
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ARHGAP26 deficiency drives the oocyte aneuploidy and early embryonic development failure Cell Death Differ. (IF 13.7) Pub Date : 2024-09-23 Sen Li, Yu Zhang, Ruiying Yuan, Shuai Zhu, Jie Bai, Yilong Miao, Xianghong Ou, Qiang Wang, Bo Xiong
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The IDH1-R132H mutation aggravates cisplatin-induced acute kidney injury by promoting ferroptosis through disrupting NDUFA1 and FSP1 interaction Cell Death Differ. (IF 13.7) Pub Date : 2024-09-22 Kunmei Lai, Zhimin Chen, Siyi Lin, Keng Ye, Ying Yuan, Guoping Li, Yankun Song, Huabin Ma, Tak W. Mak, Yanfang Xu
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The long non-coding RNA ROSALIND protects the mitochondrial translational machinery from oxidative damage Cell Death Differ. (IF 13.7) Pub Date : 2024-09-18 Vicky Katopodi, Alessandro Marino, Nikoleta Pateraki, Yvessa Verheyden, Sonia Cinque, Elena Lara Jimenez, Sara Adnane, Ewout Demesmaeker, Alice Scomparin, Rita Derua, Elisabetta Groaz, Eleonora Leucci
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Retention of ES cell-derived 129S genome drives NLRP1 hypersensitivity and transcriptional deregulation in Nlrp3tm1Flv mice Cell Death Differ. (IF 13.7) Pub Date : 2024-09-17 Felix D. Weiss, Yubell Alvarez, Farhad Shakeri, Anshupa Sahu, Petro Leka, Alesja Dernst, Jessika Rollheiser, Matilde Vasconcelos, Adriana Geraci, Fraser Duthie, Rainer Stahl, Hye Eun Lee, Anne-Kathrin Gellner, Andreas Buness, Eicke Latz, Felix Meissner
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Feeding cancer to death - a triad of aromatic acids reduces tumor growth Cell Death Differ. (IF 13.7) Pub Date : 2024-09-12 Audrey Xavier, Ivan Dikic
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The E3 ligase ASB3 downregulates antiviral innate immunity by targeting MAVS for ubiquitin-proteasomal degradation Cell Death Differ. (IF 13.7) Pub Date : 2024-09-12 Mingyang Cheng, Yiyuan Lu, Jiarui Wang, Haixu Wang, Yu Sun, Wenhui Zhao, Junhong Wang, Chunwei Shi, Jiawei Luo, Ming Gao, Tianxin Yu, Jianzhong Wang, Jiayao Guan, Nan Wang, Wentao Yang, Yanlong Jiang, Haibin Huang, Guilian Yang, Xin Cao, Dongqin Yang, Chunfeng Wang, Yan Zeng
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Inhibition of nucleo-cytoplasmic proteasome translocation by the aromatic amino acids or silencing Sestrin3—their sensing mediator—is tumor suppressive Cell Death Differ. (IF 13.7) Pub Date : 2024-09-12 Ido Livneh, Bertrand Fabre, Gilad Goldhirsh, Chen Lulu, Adar Zinger, Yael Shammai Vainer, Maya Kaduri, Aviva Dahan, Tamar Ziv, Avi Schroeder, Yinon Ben-Neriah, Yaniv Zohar, Victoria Cohen-Kaplan, Aaron Ciechanover
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Intracellular zinc protects tumours from T cell-mediated cytotoxicity Cell Death Differ. (IF 13.7) Pub Date : 2024-09-11 Emily J. Lelliott, Jonathan Naddaf, Katherine Ganio, Jessica Michie, Shelly Wang, Lin Liu, Natasha Silke, Antonio Ahn, Kelly M. Ramsbottom, Amelia J. Brennan, Andrew J. Freeman, Shom Goel, Stephin J. Vervoort, Conor J. Kearney, Paul A. Beavis, Christopher A. McDevitt, John Silke, Jane Oliaro
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PHGDH/SYK: a hub integrating anti-fungal immunity and serine metabolism Cell Death Differ. (IF 13.7) Pub Date : 2024-09-10 Xinyong Zhang, Dongdong Hu, Xiaoyan Sun, Yichun Gu, Yong Zhou, Chuanxin Su, Shi Liu, Caiyan Zhang, Guoping Lu, Qiwen Wu, Aidong Chen
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Foxk1 promotes bone formation through inducing aerobic glycolysis Cell Death Differ. (IF 13.7) Pub Date : 2024-09-05 Chungeng Liu, Naibo Feng, Zhenmin Wang, Kangyan Zheng, Yongheng Xie, Hongyu Wang, Houqing Long, Songlin Peng
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A chromosome-coupled ubiquitin-proteasome pathway is required for meiotic surveillance Cell Death Differ. (IF 13.7) Pub Date : 2024-09-05 Ruirui Zhang, Bohan Liu, Yuqi Tian, Mingyu Xin, Qian Li, Xiuhua Huang, Yuanyuan Liu, Li Zhao, Feifei Qi, Ruoxi Wang, Xiaoqian Meng, Jianguo Chen, Jun Zhou, Jinmin Gao
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Inhibition of inflammatory osteoclasts accelerates callus remodeling in osteoporotic fractures by enhancing CGRP+TrkA+ signaling Cell Death Differ. (IF 13.7) Pub Date : 2024-09-02 Yuexia Shu, Zhenyu Tan, Zhen Pan, Yujie Chen, Jielin Wang, Jieming He, Jia Wang, Yuan Wang
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LUBAC enables tumor-promoting LTβ receptor signaling by activating canonical NF-κB Cell Death Differ. (IF 13.7) Pub Date : 2024-08-30 Yu-Guang Chen, Eva Rieser, Amandeep Bhamra, Silvia Surinova, Peter Kreuzaler, Meng-Hsing Ho, Wen-Chiuan Tsai, Nieves Peltzer, Diego de Miguel, Henning Walczak
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Gelsolin alleviates rheumatoid arthritis by negatively regulating NLRP3 inflammasome activation Cell Death Differ. (IF 13.7) Pub Date : 2024-08-24 Jiyeon Lee, Fumiyuki Sasaki, Eri Koike, Minjeong Cho, Yeongun Lee, So Hee Dho, Jina Lee, Eunji Lee, Eri Toyohara, Mika Sunakawa, Mariko Ishibashi, Huynh Hiep Hung, Saki Nishioka, Ritsuko Komine, Chiaki Okura, Masumi Shimizu, Masahito Ikawa, Akihiko Yoshimura, Rimpei Morita, Lark Kyun Kim
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Deficiency of thiosulfate sulfurtransferase mediates the dysfunction of renal tubular mitochondrial fatty acid oxidation in diabetic kidney disease Cell Death Differ. (IF 13.7) Pub Date : 2024-08-22 Jia Xiu Zhang, Pei Pei Chen, Xue Qi Li, Liang Li, Qin Yi Wu, Gui Hua Wang, Xiong Zhong Ruan, Kun Ling Ma
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The PM20D1-NADA pathway protects against Parkinson’s disease Cell Death Differ. (IF 13.7) Pub Date : 2024-08-22 Yunying Yang, Sichun Chen, Li Zhang, Guoxin Zhang, Yan Liu, Yiming Li, Li Zou, Lanxia Meng, Ye Tian, Lijun Dai, Min Xiong, Lina Pan, Jing Xiong, Liam Chen, Hua Hou, Zhui Yu, Zhentao Zhang
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CCKBR+ cancer cells contribute to the intratumor heterogeneity of gastric cancer and confer sensitivity to FOXO inhibition Cell Death Differ. (IF 13.7) Pub Date : 2024-08-20 Zhenya Tan, Ke Pan, Minqiong Sun, Xianzhu Pan, Zhi Yang, Zhiling Chang, Xue Yang, Jicheng Zhu, Li Zhan, Yakun Liu, Xiaofei Li, Keqiong Lin, Lin Chen, Hui Mo, Wei Luo, Chen Kan, Lunxi Duan, Hong Zheng
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Adapting cytoskeleton-mitochondria patterning with myocyte differentiation by promyogenic PRR33 Cell Death Differ. (IF 13.7) Pub Date : 2024-08-15 Xuyang Fu, Feng Zhang, Xiaoxuan Dong, Linbin Pu, Yan Feng, Yang Xu, Feng Gao, Tian Liang, Jianmeng Kang, Hongke Sun, Tingting Hong, Yunxia Liu, Hongmei Zhou, Jun Jiang, Deling Yin, Xinyang Hu, Da-Zhi Wang, Jian Ding, Jinghai Chen
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AMDHD1 acts as a tumor suppressor and contributes to activation of TGF-β signaling pathway in cholangiocarcinoma Cell Death Differ. (IF 13.7) Pub Date : 2024-08-14 Zuyi Ma, Jia Sun, Zhenchong Li, Shanzhou Huang, Binglu Li
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LIM domain only 7: a novel driver of immune evasion through regulatory T cell differentiation and chemotaxis in pancreatic ductal adenocarcinoma Cell Death Differ. (IF 13.7) Pub Date : 2024-08-14 Shangnan Dai, Yunpeng Peng, Guangfu Wang, Chongfa Chen, Qiuyang Chen, Lingdi Yin, Han Yan, Kai Zhang, Min Tu, Zipeng Lu, Jishu Wei, Qiang Li, Junli Wu, Kuirong Jiang, Yi Zhu, Yi Miao
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Cullin 4B-RING E3 ligase negatively regulates the immunosuppressive capacity of mesenchymal stem cells by suppressing iNOS Cell Death Differ. (IF 13.7) Pub Date : 2024-08-14 Ruiqi Yu, Hong Han, Shuxian Chu, Liping Qin, Mengying Du, Yanyan Ma, Yufeng Wang, Wei Jiang, Yu Song, Yongxin Zou, Molin Wang, Qiao Liu, Baichun Jiang, Yaoqin Gong, Gongping Sun
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Rewiring cancer cell death: LPCAT1 shapes lipid composition and ferroptosis resistance Cell Death Differ. (IF 13.7) Pub Date : 2024-08-13 Hyemin Lee, Li Zhuang, Boyi Gan
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The PRMT6/STAT1/ACSL1 axis promotes ferroptosis in diabetic nephropathy Cell Death Differ. (IF 13.7) Pub Date : 2024-08-13 Jia Hong, Xue Li, Yingxiang Hao, Hongjiao Xu, Lang Yu, Zhipeng Meng, Jianhai Zhang, Minmin Zhu
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Vps34 sustains Treg cell survival and function via regulating intracellular redox homeostasis Cell Death Differ. (IF 13.7) Pub Date : 2024-08-08 Peiran Feng, Quanli Yang, Liang Luo, Zerong Guan, Jiamin Fu, Mingyue Zhao, Wanqing Meng, Shuo Wan, Junming He, Zhizhong Li, Guang Wang, Guodong Sun, Zhongjun Dong, Meixiang Yang
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Novel role for Ddx39 in differentiation and telomere length regulation of embryonic stem cells Cell Death Differ. (IF 13.7) Pub Date : 2024-08-06 Shanshan Nai, Meijie Wang, Jiao Yang, Bin Ling, Qiman Dong, Xiaoqiong Yang, Xiaoling Du, Man Lu, Lin Liu, Zhongbo Yu, Lingyi Chen
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Phospholipid peroxidation in macrophage confers tumor resistance by suppressing phagocytic capability towards ferroptotic cells Cell Death Differ. (IF 13.7) Pub Date : 2024-08-05 Xiang Luo, Hai-Biao Gong, Zi-Chun Li, Dong-Dong Li, Zi-Xuan Li, Jie Sun, Chang-Yu Yan, Rui-Ting Huang, Yue Feng, Shu-Rui Chen, Yun-Feng Cao, Mingxian Liu, Rong Wang, Feng Huang, Wan-Yang Sun, Hiroshi Kurihara, Wen-Jun Duan, Lei Liang, Wen Jin, Yan-Ping Wu, Rong-Rong He, Yi-Fang Li
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TOX2 nuclear-cytosol translocation is linked to leukemogenesis of acute T-cell leukemia by repressing TIM3 transcription Cell Death Differ. (IF 13.7) Pub Date : 2024-07-30 Anzhou Li, Junbao Zhang, Liangping Zhan, Xiufeng Liu, Xiliang Zeng, Qian Zhu, Zifeng Wang, Jiang Li
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TIN2 modulates FOXO1 mitochondrial shuttling to enhance oxidative stress-induced apoptosis in retinal pigment epithelium under hyperglycemia Cell Death Differ. (IF 13.7) Pub Date : 2024-07-30 Shimei Chen, Dandan Sun, Shuchang Zhang, Li Xu, Ning Wang, Huiming Li, Xun Xu, Fang Wei
更新日期：2024-11-13
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