Lysine methylation steps into another step of the central dogma,Cell Research

当前位置： X-MOL 学术 › Cell Res. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Lysine methylation steps into another step of the central dogma
Cell Research ( IF 28.1 ) Pub Date : 2024-09-17 , DOI: 10.1038/s41422-024-01033-z
Zuodong Zhao ₁ , Bing Zhu _{1,

2,

3}

Affiliation

Lysine methylation is an important protein modification that regulates replication and transcription, the fundamental events of the central dogma. However, whether it plays a role in translation, the last step of the central dogma, remains unclear. Two recent studies revealed that lysine methyltransferase SMYD5 catalyzes the trimethylation of lysine 22 in ribosomal protein RPL40, enhances translation output, and promotes cancer progression.

中文翻译：