Correction to: Nature Neuroscience https://doi.org/10.1038/s41593-024-01806-0, published online 3 December 2024.

Correction to: Nature Neuroscience https://doi.org/10.1038/s41593-022-01022-8, published online 8 Marcxh 2022.

Correction to: Nature Neuroscience https://doi.org/10.1038/s41593-021-00908-3, published online 26 August 2021.

Correction to: Nature Neuroscience https://doi.org/10.1038/s41593-022-01161-y, published online 20 October 2022.

Immune cells that originate in the meninges have an increasingly appreciated role in brain development and homeostasis. Most studies of this role have focused on meningeal T cells; now, writing in Science, Barron et al. show that innate lymphoid cells (ILCs) regulate the development of inhibitory neurons in the mouse prefrontal cortex. Throughout postnatal brain development, meningeal innate lymphocytes

Serotonin is primarily known for its roles in the CNS, but it is also produced by Tph2-expressing enteric neurons. A study published in Nature Communications by Zhang et al. suggests that enteric serotonergic neurons influence gut immune function. The authors observed that mice with constitutive or enteric neuron-specific loss of Tph2 have increased susceptibility to oral infection from the bacterial

Amygdalo–striatal neurons have been implicated in the processing of appetitive and aversive valence. Adding to our understanding of this neural pathway’s heterogeneity, Tian, Song et al. found that mice in which the anterior commissure was transected, which lack interhemispheric projections from basolateral amygdala (BLA) to contralateral nucleus accumbens (NAc), show blunted aversion. Strikingly,

A successful chess player uses knowledge of past strategies and games to anticipate their opponent’s moves, adapting their play on the basis of the specific board configuration and planning several moves ahead. Context-specific past experiences provide important insights for making predictions about future events. In Nature Communications, Tarder-Stoll et al. describe how they explored, using immersive

Single-cell genomics is deepening our understanding of the nervous system and shedding light on the heterogeneity of its cells. This focus issue of Nature Neuroscience celebrates recent methodological and analytical advances in single-cell genomics, highlights principles of study design, and aims to encourage collaboration between cellular, molecular and systems neuroscientists.

Klaus Miczek was born in Germany and earned his BA degree at the Padagogische Hochschule-Berlin in 1966. He completed his graduate training at the University of Chicago, Illinois, where he began studying aggressive behavior and operant models of conditioned aversion under the mentorship of Sebastian P. Grossman. After receiving his PhD in 1972, he accepted a faculty position at Carnegie-Mellon University

Although functional imaging studies have shown that odors activate the human piriform cortex, amygdala, entorhinal cortex and hippocampus, it remains unclear which aspects of odors — such as identity and valence — are encoded where in the brain. Kehl et al. recorded from thousands of individual neurons in these four brain areas in humans performing a task requiring them to rate (like or dislike) and

Original references: Nature 634, 124–138 (2024); Nature 634, 139–152 (2024)

Alcohol’s effects on the brain are mediated in part through its action as a positive allosteric modulator (PAM) at GABAA receptors (GABAARs), but the molecular mechanisms that connect GABAARs and alcohol-related behaviors remain unclear. To address this question, Wang et al. began by using a proteomic approach to examine differential levels of plasma membrane proteins in hippocampal samples from individuals

Breast cancer cells that metastasize to the brain are often fatal, and few effective therapies are available. In a recent study published in Nature Cell Biology, Yuzhalin et al. identified the cyclin-dependent kinase CDK5 as a potential therapeutic target for these brain metastases. Out of all cyclin-dependent kinase genes, CDK5 was the most upregulated in human brain metastases compared to matched

Ernest Arenas, Professor at the Karolinska Institutet, passed away on 15 September 2024 at the age of 62 in Stockholm, Sweden. Ernest made unique contributions to the field of Parkinson’s disease research, with a strong commitment to developing improved treatment strategies through cell replacement therapy.