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Knowing when to stop: MICL self-regulates neutrophil NETosis
Cell Research ( IF 28.1 ) Pub Date : 2024-10-14 , DOI: 10.1038/s41422-024-01037-9 Hanjoo Brian Shim, Justin François Deniset, Paul Kubes
中文翻译:
知道何时停止:MICL 自我调节中性粒细胞 NETosis
更新日期:2024-10-14
Cell Research ( IF 28.1 ) Pub Date : 2024-10-14 , DOI: 10.1038/s41422-024-01037-9 Hanjoo Brian Shim, Justin François Deniset, Paul Kubes
In a recent study published in Nature, Malamud et al. identified how neutrophil MICL recognizes neutrophil extracellular traps (NETs). This recognition suppresses further neutrophil activation and NET production, thereby preventing a vicious cycle of inflammation.
中文翻译:
知道何时停止:MICL 自我调节中性粒细胞 NETosis
在最近发表在《自然》杂志上的一项研究中,Malamud 等人确定了中性粒细胞 MICL 如何识别中性粒细胞胞外陷阱 (NET)。这种识别抑制了进一步的中性粒细胞活化和 NET 产生,从而防止了炎症的恶性循环。