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Heat acclimation induces hypothalamic temperature sensitivity that promotes heat tolerance
Nature Neuroscience ( IF 21.2 ) Pub Date : 2024-12-17 , DOI: 10.1038/s41593-024-01835-9


After long-term heat exposure, a discrete group of hypothalamic neurons in the anterior ventromedial preoptic area become hyperactive and acquire temperature sensitivity. This reversible plasticity mechanism renders mice heat tolerant, meaning they can keep their body temperature within physiological limits when ambient temperatures are high.

中文翻译:


热驯化会引起下丘脑温度敏感性,从而促进耐热性



长期热暴露后,前腹内侧视前区的一组离散的下丘脑神经元变得过度活跃并获得温度敏感性。这种可逆的可塑性机制使小鼠具有耐热性,这意味着当环境温度较高时,它们可以将体温保持在生理范围内。
更新日期:2024-12-17
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