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Raman Spectral Feature Enhancement Framework for Complex Multiclassification Tasks Anal. Chem. (IF 6.7) Pub Date : 2024-12-20 Jiaqi Hu, Chenlong Xue, Ken Xiaokeng Chi, Junyu Wei, Zhicheng Su, Qiuyue Chen, Ziyu Ou, Shuxin Chen, Zhe Huang, Yilin Xu, Haoyun Wei, Yanjun Liu, Perry Ping Shum, Gina Jinna Chen
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Microneedle-Based Electrochemical Array Patch for Ultra-Antifouling and Ultra-Anti-Interference Monitoring of Subcutaneous Oxygen Anal. Chem. (IF 6.7) Pub Date : 2024-12-20 Jiaxi Liu, Jiang Liu, Yanyan Liang, Jiao Yang, Yongping Lin, Yingchun Li
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A Modern Framework for Analytical Procedure Development and Lifecycle Management Based on ICH Q14 Principles Anal. Chem. (IF 6.7) Pub Date : 2024-12-20 Max Eberle, Jamie T. Wasylenko, Drazen Kostelac, Sarah Kiehna, Adam Schellinger, Zhaorui Zhang, Jason D. Ehrick
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Advanced Mass-Spectra-Based Machine Learning for Predicting the Toxicity of Traditional Chinese Medicines Anal. Chem. (IF 6.7) Pub Date : 2024-12-20 Chen Jia, Xiaofang Li, Song Hu, Guohong Liu, Jiansong Fang, Xiaoxia Zhou, Xiliang Yan, Bing Yan
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miR-Cabiner: A Universal microRNA Sensing Platform Based on Self-Stacking Cascaded Bicyclic DNA Circuit-Mediated CRISPR/Cas12a Anal. Chem. (IF 6.7) Pub Date : 2024-12-20 Ruijia Deng, Jing Sheng, Zuowei Xie, Hongzhao Yang, Sha Yang, Shuang Xie, Xiaoqi Tang, Shuang Zhao, Haohao Dong, Ming Chen, Kai Chang
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TG-MS Analysis for Elemental Composition of Organic Matters and Their Structural Properties Anal. Chem. (IF 6.7) Pub Date : 2024-12-20 Lin Lin, Sasha Yang, Fuhong Zhang, Muxin Liu, Dong Liu, Lei Shi
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MWFormer: Estimation of Molecular Weights from Electron Ionization Mass Spectra for Improved Library Searching Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Qiong Yang, Hailiang Zhang, Yue Wang, Lin Tan, Ting Xie, Yufei Wang, Jia Long, Zixuan Guo, Zhimin Zhang, Hongmei Lu
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Introducing “Identification Probability” for Automated and Transferable Assessment of Metabolite Identification Confidence in Metabolomics and Related Studies Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Thomas O. Metz, Christine H. Chang, Vasuk Gautam, Afia Anjum, Siyang Tian, Fei Wang, Sean M. Colby, Jamie R. Nunez, Madison R. Blumer, Arthur S. Edison, Oliver Fiehn, Dean P. Jones, Shuzhao Li, Edward T. Morgan, Gary J. Patti, Dylan H. Ross, Madelyn R. Shapiro, Antony J. Williams, David S. Wishart
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Polyvalent Aptamers Structure-Mediated Fluorescent Aptasensor for the Early Diagnosis of Alzheimer’s Disease by Coupling with HCR and CRISPR-Cas System Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Xinyi Li, Bingjie Chen, Yaoyao Xie, Yi Luo, Dan Zhu, Lianhui Wang, Shao Su
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A–D–A Molecular Design Strategy Enabling Ultrasensitive NIR Vapor Sensing Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Wenxing Xu, Kangbo Zhen, Wancheng Bao, Zezong Shi, Xiuyun Jiang, Kai Qi, Wei Xu, Zhengqi Shen, Chunhui Li, Zhaohui Zhu, Huan Liu, Bo Wang, Qingguo He, Huizi Li, Jiangong Cheng, Xiang Ma, Yanyan Fu
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Electrochemiluminescence Detecting and Imaging of Yeast Metabolism Indicated by Endogenetic Co-reactant Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Jiancong Ni, Shengxiu Huang, Weiqiang Yang, Qiaoling Chen, Zhenyu Lin
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CRISPR/Cas12a-Enabled Amplification-Free Colorimetric Visual Sensing Strategy for Point-of-Care Diagnostics of Biomarkers Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Zhe Zhao, Qing Xiong, Yan Zhu, Cong Zhang, Zhixin Li, Zhonghui Chen, Ying Zhang, Xiaoyu Deng, Yingzhou Tao, Shaohua Xu
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Carbon dot embedded hybrid microgel from synthesis to sensing: Experimental and theoretical approach Anal. Chim. Acta (IF 5.7) Pub Date : 2024-12-20 Neha Garg, Ankita Garg, Aman Bhalla, Savita Chaudhary, Abhijit Dan
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Entropy driven-based catalytic biosensors for bioanalysis: From construction to application-A review Anal. Chim. Acta (IF 5.7) Pub Date : 2024-12-20 Sha Yang, Xinyu Zhan, Lijia Yuan, Marc Lamy de la Chapelle, Weiling Fu, Xiang Yang
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Innovative Separation of Melittin from Bee Venom Using Micro-Free-Flow Electrophoresis: An Experimental and Theoretical Study Anal. Chim. Acta (IF 5.7) Pub Date : 2024-12-19 Azadeh Kordzadeh, Ahmad Ramazani SA, Shohreh Mashayekhan
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Microfluidic Fractionation of Microplastics, Bacteria and Microalgae with Induced-charge Electro-osmotic Eddies Anal. Chim. Acta (IF 5.7) Pub Date : 2024-12-19 Xiaoming Chen, Ziwei Gao, Jishun Shi, Yingxuan Liu, Zhipeng Song, Chungang Wu, Li Su, Zhouyang Zhang, Yong Zhao
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Simultaneous radionuclide determination using PSresin: 2in2 and 2in1 tandem configuration Anal. Chim. Acta (IF 5.7) Pub Date : 2024-12-19 I. Giménez, H. Bagán, A. Tarancón
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Lysosome-targeted dual-locked NIR fluorescent probe for visualization of H2S and viscosity in drug-induced liver injury and tumor models Anal. Chim. Acta (IF 5.7) Pub Date : 2024-12-17 Jingcan Qin, Fei Kong, Jie Huang, Bang Xiao, Yun Bian, Chengwei Shao
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A label-free electrochemical biosensor based on graphene quantum dots-nanoporous gold nanocomposite for highly sensitive detection of glioma cell Anal. Chim. Acta (IF 5.7) Pub Date : 2024-12-16 Xiaohui Wang, Xinran Li, Baoquan Wang, Yanxia Xie, Xueru Cui, Jin Jiao, Jianwei Jiao, Yachao Zhang
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Non-tandem enzymatic modules-encapsulated metal-organic framework cubes with mutual-validated operation for dual-modal competitive immunoassay of antibiotics Sens. Actuators B Chem. (IF 8.0) Pub Date : 2024-12-19 Yi Yang, Licheng Yu, Liang He, Pengli Bai, Xiwen He, Langxing Chen, Yukui Zhang
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Dual-gas sensor for ultra-close overlapping spectra based on second harmonic peak shift Sens. Actuators B Chem. (IF 8.0) Pub Date : 2024-12-19 Huifang Gao, Qing Yang, Qianjin Wang, Zhirong Zhang, Yuangang Lu, Le Wang
In spectral absorption techniques, overlapping spectra cause distortion in absorption line heights, leading to inaccuracies in concentration measurements, which poses a significant challenge for measuring multi-component gases. In this paper, an innovative method that utilizes the displacement of the second harmonic (2f) peak to mitigate 2f height errors resulting from cross-interference is presented
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Girard Derivatization-Based Enrichment Strategy for Profiling the Carbonyl Submetabolome in Biological Samples Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Xin Tao, Jia-Yue Liu, Jun-Yi Zhou, Jiang-Kun Dai, Zeyu Xiao, Hou-Kai Li, Jian-Bo Wan
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Aptamer-Based Activatable Tyramide Signal Amplification for Low-Background Detection of SARS-CoV-2 Nucleocapsid Protein Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Zhiyong Huang, Ziyan Du, Juan Li, Da Han, Jiaxuan He, Yunben Yang, Dan Wang, Yu Liang, Yunshan Yang, Ruizi Peng, Weihong Tan
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Electric Field Distribution in Bipolar Electrochemical Cells: Effects on the Wirefree Electrodeposition of Conducting Polymer Films Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Áine Brady, Robert J. Forster
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Pair-Soil-Spectra: An Approach for NIRS-Based Soil Total Nitrogen Content Detection with Feature Metrics in Cases of Small Sample Sizes Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Yueting Wang, Chunjiang Zhao, Zhen Xing, Mingyan Zhu, Lianglin Hao, Ke Wang, Juekun Bai, Hongwu Tian, Daming Dong
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Electrochemical Quantification of miRNA Based on Strain-Promoted Azide–Alkyne Cycloaddition Ligated Tetrahedral DNA Nanotags Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Yuzhu Ma, Tingting Wang, Xiaolin Qu, Ruhong Yan, Peng Miao
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Development of a Nanobody–Alkaline Phosphatase Fusion Protein for Detection of SARS-CoV-2 Spike Protein in a Fluorescence Enzyme Immunoassay Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Heng Liu, Qianling Su, Siliang Duan, Xianing Huang, Xiaomei Yang, Aiqun Liu, Shiquan Liu, Chun Xu, Xiaoling Lu
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Visual Detection of Methylglyoxal in Multiple Scenarios via NIR-Excitable Reversible Ratiometric Fluorescent Hydrogel Sensor Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Xiaohui Kang, Lanpeng Zhang, Wei Jia, Liang Yang, Changlong Jiang
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Differential Mobility Spectrometry Acoustic Ejection Mass Spectrometer System for Screening Isomerization-Mediating Enzyme Drug Targets Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Samad Bazargan, Patricia Dranchak, Chang Liu, James Inglese, John Janiszewski, Bradley B. Schneider, Thomas R. Covey
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An Entropy-Driven Multipedal DNA Walker Microsensor for In Situ Electrochemical Detection of ATP Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Hong Jiang, Xiao Liu, Dong Zhao, Yu-Kang Jia, Ya-Qin Wang, Wei Li, Zhao-Peng Liu, Ji-Dong Wang
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Electrochemical Behaviors of Ultramicro Triangular Pipettes Anal. Chem. (IF 6.7) Pub Date : 2024-12-18 Yutong Hua, Junjie Liu, Deyi Zhang, Jintao Deng, Chang Liu, Xianhao Zhang, Zhiwei Zhu, Huan Wang, Yuanhua Shao
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Transcending Resolution Limits in HPLC and Diffusion NMR Anal. Chem. (IF 6.7) Pub Date : 2024-12-18 Nouran A. Hamed, Alexandria K. Shread, Gareth A. Morris, Mathias Nilsson
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Medium entropy-derived flower-like FeCeCu nanozyme with excellent oxidase-like activity for on-site and visual detection of carbosulfan Anal. Chim. Acta (IF 5.7) Pub Date : 2024-12-19 Wanning Li, Taimei Cai, Jianwen Tian, Yaru Dong, Fuqiang Hu, Hailong Peng
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Determination of alkali metal elements in solid biomass fuel by laser-induced breakdown spectroscopy: analysis and reduction of chemical matrix effects Anal. Chim. Acta (IF 5.7) Pub Date : 2024-12-19 Chengjun Li, Zhimin Lu, Jinzheng Chen, Ziyu Yu, Qi Yang, Huaiqing Qin, Xiwen Xing, Qingxiang Ma, Shunchun Yao
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Preparation, mechanism, and biological applications of targeting LDs ratiometric fluorescent probes for HClO detection Anal. Chim. Acta (IF 5.7) Pub Date : 2024-12-18 Weiling Yan, Ying Liu, Yuhang Wang, Shizeng Pei, Caihong Zhang, Guomei Zhang, Shaomin Shuang, Chuan Dong
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Stylus Pen-based Ambient Ionization Mass Spectrometry for the Analysis of Volatiles and Semivolatiles from Liquid, Viscous, and Solid Samples Anal. Chim. Acta (IF 5.7) Pub Date : 2024-12-18 Yi-Ying Wu, Chin-Pao Chiu, Yu-Chie Chen
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Enhancing the Interactions of Ion-Tagged Oligonucleotides and Magnetic Ionic Liquid Supports for the Sequence-Specific Extraction of Hepatitis B Virus DNA Anal. Chim. Acta (IF 5.7) Pub Date : 2024-12-18 Seong-Soo Lee, Derek R. Eitzmann, Jared L. Anderson
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3D-Printable Rotary Valves for Low-Pressure Pneumatic and Fluidic Applications in Analytical Chemistry Anal. Chem. (IF 6.7) Pub Date : 2024-12-18 Tomas Drevinskas, Andrew Berg, Aaron C. Noell, Mauro S. Ferreira Santos, Maria F. Mora, Peter A. Willis
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Ligand engineering boosts catalase-like activity of gold nanoclusters for cascade reactions combined with glucose oxidase in ZIF-8 matrix Anal. Chim. Acta (IF 5.7) Pub Date : 2024-12-18 Yi-Shu Wang, Chen Dong, Li Zou, Lin Zhao, Jian-Hua Qin, Hui-Lin Mo
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A novel 3D-printed sample preparation method for benzodiazepine quantification in human serum Anal. Chim. Acta (IF 5.7) Pub Date : 2024-12-15 Dagmara Kroll, Szymon Ulenberg, Paweł Georgiev, Bartosz Marciniak, Gert Desmet, Tomasz Bączek, Mariusz Belka
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A Novel Label-Free Method for Efficient Detection of Bisphosphonate Drug Dissolution Rates Using Surface-Enhanced Raman Spectroscopy Anal. Chem. (IF 6.7) Pub Date : 2024-12-18 Li Zhang, Junting Wang, Shuang Jiang, Zheng Feng, Yuanqiu Mu, Zhibin Wang, Chunli Gan, Xiaotong Wang, Yue Zhao, Huimin Yu, Chunjuan Yang, Yang Li
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SlipChip Enables the Integration of CRISPR-Cas12a and RPA for Fast and Stand-Alone HPV Detection Anal. Chem. (IF 6.7) Pub Date : 2024-12-18 Yin Zhao, Zheyu Li, Tao Li, Ruotong Rao, Jiang Zhu, Rui Hu, Guoyong Xu, Ying Li, Yunhuang Yang
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Advanced SERS Platform for Uniform and Reliable Molecular Detection Anal. Chem. (IF 6.7) Pub Date : 2024-12-18 Tiying Zhu, Zhiyang Pei, Xiaofei Zhao, Jing Yu, Baoyuan Man, Pingheng Tan, Zhen Li, Chao Zhang
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A Novel System for Simultaneous Real-Time Determination of 15N-Enriched Ammonia, Hydroxylamine, Nitrite, and Nitrate Anal. Chem. (IF 6.7) Pub Date : 2024-12-18 Jing Wei, Zheyan Zhou, Yunjie Zhang, Xiao Ma, Longfei Yu, Teng Wen, Jinbo Zhang, Qing Mu, Wenping Yuan
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Specific Response Assembly of 3D Space-Confined DNA Nanoaggregates for Rapid and Sensitive Detection of DNA Methyltransferase Anal. Chem. (IF 6.7) Pub Date : 2024-12-18 Jia-Hao Tang, Wei Liu, Mao-Hua Gao, Xian-Ming Guo, Yan-Mei Lei, Ying Zhuo
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Biomimetic Honeycomb-like Ti3C2Tx MXene/Bacterial Cellulose Aerogel-Based Flexible Pressure Sensor for the Human–Computer Interface ACS Sens. (IF 8.2) Pub Date : 2024-12-18 Xinyu Hong, Zhijian Du, La Li, Kai Jiang, Di Chen, Guozhen Shen
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A MXene-Au Nanosheets-based Fluorescent-SERS Dual-Mode Biosensor Integrated with CRISPR/Cas12a System for Endotoxin Detection Sens. Actuators B Chem. (IF 8.0) Pub Date : 2024-12-19 Honglian Wu, Ruolin Zhang, Huang Lai, Lai luogen, Yi Liu, Yadi Fan, Yu Zhang, Jingyu Shi, Mo Yang
Endotoxins or lipopolysaccharides (LPS) are potent inflammatory agents that pose serious health risks even at low concentrations, thus requiring sensitive and reliable detection methods. Current methods for endotoxin detection, primarily the Limulus Amebocyte Lysate (LAL) assay and Enzyme-linked Immunosorbent Assays (ELISA) are limited by complex procedures, prolonged assay time, and susceptibility
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Dual-site peroxidase-mimic graphdiyne-based colorimetric sensor arrays with machine learning for screening of multiple antibiotics Sens. Actuators B Chem. (IF 8.0) Pub Date : 2024-12-19 Xingchen Qiu, Jianyu Yang, Rui Bai, Mengdi Zhao, Changfa Shao, Qingqing Zhao, Yu Gu, Chunxian Guo, Chang-Ming Li
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Self-powered sensor based on a TiO2 NTAs/FeN5 SACs photocatalytic fuel cell for sensing chemical oxygen demand Sens. Actuators B Chem. (IF 8.0) Pub Date : 2024-12-17 Yuehan Zhang, He Zhang, Xiaoxuan Sun, Panpan Zhao, Junfeng Zhai, Shaojun Dong
Chemical oxygen demand (COD) is a crucial parameter in assessing water quality. Due to the improved public awareness of environmental protection, the rapid, eco-friendly, and cost-effective methods for COD measurement are highly desired. This work proposes a new self-powered COD sensor (SPCS), based on a photocatalytic fuel cell composed of a FeN5 single-atom nanozymes (FeN5 SACs)/ITO cathode and a
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Handheld biofluorometric system for acetone in the exhaled breath condensates Analyst (IF 3.6) Pub Date : 2024-12-19 Geng Zhang, Kenta Ichikawa, Kenta Iitani, Yasuhiko Iwasaki, Kohji Mitsubayashi
As a marker of human metabolism, acetone is important for lipid metabolism monitoring and early detection of diabetes. In this study, we developed a handheld acetone biosensor based on fluorescence detection by utilizing the enzymatic reaction of secondary alcohol dehydrogenase (S-ADH) with β-nicotinamide adenine dinucleotide (NADH, λex = 340 nm, λem = 490 nm). In the reaction, NADH is oxidized when
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An intimal-lumen model in a microfluidic device: potential platform for atherosclerosis-related studies. Lab Chip (IF 6.1) Pub Date : 2024-12-19 Fahima Akther,Dimple Sajin,Shehzahdi S Moonshi,Jessica Pickett,Yuao Wu,Jun Zhang,Nam-Trung Nguyen,Hang Thu Ta
Atherosclerosis is a chronic inflammatory vascular disorder driven by factors such as endothelial dysfunction, hypertension, hyperlipidemia, and arterial calcification, and is considered a leading global cause of death. Existing atherosclerosis models have limitations due to the absence of an appropriate hemodynamic microenvironment in vitro and interspecies differences in vivo. Here, we develop a
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Developing Multiple Media Approach to Investigate Reproducible Characteristic VOCs of Lung Cancer Cells Anal. Chem. (IF 6.7) Pub Date : 2024-12-18 Jijuan Zhou, Dianlong Ge, Yue Liu, Yajing Chu, Xiangxue Zheng, Yan Lu, Yannan Chu
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Manipulating Near-Infrared Absorption via Engineering Anisotropic Plasmonic Spiky Au Nanocubes for the Highly Efficient Dual-Response Immune Detection of T-2 Toxin Anal. Chem. (IF 6.7) Pub Date : 2024-12-18 Rui Shu, Kexin Wang, Meilin Wang, Sijie Liu, Jiayi Zhang, Ibrahim A. Darwish, Jianlong Wang, Daohong Zhang
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Advanced Ligase Chain Reaction Strategy to Generate a Circular DNA Walker for Electrochemiluminescent Detection of Single Nucleotide Polymorphism Anal. Chem. (IF 6.7) Pub Date : 2024-12-18 Lu Yan, Xiu-Li Tao, Qiao-Lin Chen, Wen Li, Ya-Qin Chai, Ruo Yuan, Yan-Mei Lei, Ying Zhuo
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Unmixing Autoencoder for Image Reconstruction from Hyperspectral Data Anal. Chem. (IF 6.7) Pub Date : 2024-12-17 Xuyang Liu, Chaoshu Duan, Wensheng Cai, Xueguang Shao
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Real-Time Monitoring of Metal Ions during the Molten Salt Electrolysis Process by Optical Emission Spectrometry Based on Microplasma Anal. Chem. (IF 6.7) Pub Date : 2024-12-17 Junhan Luo, Jingcui Liu, Qi Qing, Shuang Liu, Zhe Wang, Jing Chen, Yuexiang Lu
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Online Monitoring of the Processing of Traditional Chinese Medicine by Neutral Desorption Atmospheric Pressure Chemical Ionization Mass Spectrometry Anal. Chem. (IF 6.7) Pub Date : 2024-12-17 Zhendong Yu, Hui Li, Luyao Zhong, Wenshan Cui, Zhi-Liang Chen, Luqi Huang, Zidong Qiu, Rui Su, Jiaquan Xu
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Time-Resolved Levodopa Cascade Polymerization Tuned by Bimetallic MOF Fluorescent Nanozyme and Boric Acid for Butyrylcholinesterase Activity Dual-Mode Assay Anal. Chem. (IF 6.7) Pub Date : 2024-12-17 Qi Xu, Shuo Wang, Zhiwen Gan, Yongzhen Liu, Long Yu, Hong Cheng, Yuxiu Xiao
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Pop-Up Paper-Based Biosensor for a Dual-Mode Lung Cancer ctDNA Assay Based on Novel CoB Nanosheets with Dual-Enzyme Activities and a Portable Smartphone/Barometer for Readout ACS Sens. (IF 8.2) Pub Date : 2024-12-18 Siyi Yang, Jiajia Zhu, Liyu Yang, Huanbao Fa, Yongzhong Wang, Danqun Huo, Changjun Hou, Daidi Zhong, Mei Yang
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Continuous Biosensing to Monitor Acute Systemic Inflammation, a Diagnostic Need for Therapeutic Guidance ACS Sens. (IF 8.2) Pub Date : 2024-12-18 Guilherme Gouveia, Abtin Saateh, Anna Swietlikowska, Claudia Scarpellini, Emily Tsang, Hatice Altug, Maarten Merkx, Annelies Dillen, Karen Leirs, Dragana Spasic, Jeroen Lammertyn, Kurt V. Gothelf, Estelle Bonedeau, Nicola Porzberg, Ruben L. Smeets, Hans J. P. M. Koenen, Menno W. J. Prins, Marien I. de Jonge