The ultrasonic micromachining systems significantly improve machining efficiency and quality, which are increasingly being applied in the manufacturing of microstructures and micro parts. However, the mechanical and thermal loads of the high-frequency piezoelectric ultrasonic transducer (HPUT) of ultrasonic micromachining systems have serious interference with the precise control of resonance frequency

Liquid atomization is utilized across various industrial applications, including nanopowder production, spray drying, fuel combustion, coating applications, emulsion preparation, and in medical devices. The use of ultrasonic energy for atomization offers advantages in terms of environmental sustainability compared to other methods. Notably, ultrasonic atomization can achieve finer dispersion with a

The yields of H2O2 and H2 formed in the sonolysis of aqueous solution under noble gas are representative indexes for understanding the chemical effects of ultrasonic cavitation bubbles. In this study, the yields of H2O2 and H2 formed under Ar were evaluated as a function of the concentration of NaCl or KI. When these yields were analyzed by using a normalization technique, it was confirmed that the

Tribulus terrestris L. is a herb renowned for its abundance of saponins, flavonoids, and alkaloids, which are utilized in treating various health conditions. Protodioscin functions by enhancing the conversion of testosterone into potent dihydrotestosterone, stimulating an increase in libido, red blood cell production from the bone marrow, and muscle development. Contemporary ultrasound-assisted-extraction

Laser direct deposition (LDD) is widely used to repair and manufacture high-value industrial components. However, it faces various defects, such as porosity, cracks, non-uniform microstructure, lack of fusion, keyhole phenomenon, element segregation, and undesirable secondary phases. A method to manage these defects is to concurrently apply ultrasonic vibrations (USV) during the LDD process. This study

Faba bean proteins are currently viewed as promising animal protein alternatives. However, certain functional properties e.g. relatively low solubility compared to whey protein isolates, can limit the application of faba bean protein isolates (FPIs) in certain food products. Therefore, it may be desirable to use modification approaches such as the application of ultrasound to alter such limiting physicochemical

This study aimed to explore the impact of varying Ca2+ concentrations and 11S/7S ratios on the gel performance of soybean protein gels (SPGs) under ultrasonication (400 W, 15 min) and to clarify the mechanisms involved. Results showed Ca2+ addition altered the structure of soybean 11S/7S protein gels. Low Ca2+ levels increased the turbidity, hardness, and water retention of the gels, whereas high levels

Soldering of ceramics/metals using an inactive commercial solder with the advantage of low cost has wide application prospects. The dissolution behavior of base metal could not be quantified, which has been a basic issue for the joining design. This work investigated the dissolution of the solid Al in liquid Sn with and without the ultrasound. The physical model for the dissolving process was established

This study investigates the potential of fused deposition modeling (FDM) three-dimensional (3D) printing techniques for manufacturing catalytic static mixers during biodiesel synthesis. The printed catalytic mixing elements comprises acrylonitrile butadiene styrene (ABS) plastic with 15 wt% calcium oxide (CaO) as a solid catalyst. When the reactants flowed through the CaO/ABS mixing device, the blending

Hydrodynamic Cavitation (HC) is a highly turbulent, unsteady, multi-phase flow that has been useful in many processing applications like wastewater treatment and process intensification and hence needs to be studied in detail. The aim of this study is to investigate the mechanisms driving HC inside a Venturi tube using numerical simulations. The numerical simulations are conducted in the form of both

For the valorization of Chaenomeles speciosa leaves, this study focused on extraction, enrichment, chemical profiling, and investigation of the biological activity of its abundant triterpenoid components. Initially, the total triterpenoids in C. speciosa leaves were extracted by ultrasonic-assisted extraction (UAE) method, with the extraction process optimized through response surface methodology (RSM)

Traditional beef jerky contains a high content of sodium salt while the reduction of sodium usage impairs the flavor of final product. Regarding above issues, this research innovatively applied ultrasound-assisted salts (NaCl and KCl) recombination in the pickling stage of low-sodium beef jerky, and further compared the flavor differences caused by ultrasound by sensory evaluation, E-nose and GC-IMS

Crayfish, as a new consumer trend, has become one of the most popular freshwater aquatic foods in China, and its processed product output has been increasing year by year. In this study, the effect of multi-frequency power ultrasound (MFPU) pretreatment in various working modes including mono-, dual- and tri-frequency on the enzymatic hydrolysis and Maillard reaction of crayfish was investigated. Additionally

This study presents the synthesis and optimization of Methylene polyethyl glycol −Polystyrene (mPEG-PS) Diblock (DIP) copolymer-based solid lipid nanoparticles (SLNs) using ultrasonication for advanced drug delivery systems targeting the human immunodeficiency virus (HIV-1). The mPEG-PS block copolymer was synthesized by ring opening polymerization mechanism under nitrogen atmosphere for 24hrs and

In orthopedic surgery, cortical bone cutting usually involves washing and cooling with physiological saline. However, how the saline changes the cutting behaviors of bone ultrasonic vibration cutting remains challenging. Hence, this paper simulates the clinical ultrasonic cutting condition in orthopedics to reveal the cutting behaviors of bone ultrasonic vibration orthogonal cutting immersed in physiological

Experimental data were analyzed to investigate the underlying adsorption or degradation mechanism of carotenoids and chlorophylls over the bleaching of sunflower oil through different amplitudes of horn and bath ultrasound (ultrasound-assisted bleaching; UAB), temperature, time, and bleaching clay. Quantifying the color removal efficiency in both batch and continuous systems, along with the corresponding

Meat products for elderly people are high in sodium content and hardness. Thus, the aim of this study is to explore how ultrasound-assisted low-sodium salting improves meat quality and determine the conditions that result in meat tenderness ideal for people aged 65–74 years. The ultrasound-assisted treatment of bovine hip muscle with non-sodium salt (CaCl2 and C6H10CaO6) was adopted, followed by sous

Anchusa italica Retz. Flowers (Airfs) is a perennial herb belonging to the Boraginaceae family. A variety of pharmacological agents are employed in the treatment of a multitude of cardiovascular disorders. The study employs ultra-performance liquid chromatography coupled with quadrupole-time of flight mass spectrometry (UPLC-Q-Exactive Orbitrap-MS) to elucidate the complex chemical composition of these

Ultrasonic-mediated plasmid transformation is a promising microbial transformation strategy with broad application prospects that has attracted interest across various fields. Limited research exists on developing a quantitative model to understand the relationship between transformation efficiency and ultrasonic power. Within the ultrasonic range that did not damage plasmids, the maximum transformation

Fig fruit (Ficus carica L.) drink is a source of healthy minerals, vitamins, and bioactive ingredients however to improve the shelf-life of functional drink naturally, moringa leaf extract was compared with optimized concentration of potassium metabisulphite (synthetic preservative). Purposely, fig fruit drink, without preservatives was considered as negative control whereas, 0.2 % potassium metabisulphite-based

The wearing of contact lenses (CLs) may cause bacterial infections, leading in turn to more serious complications and ultimately vision impairment. In this scenario, the first step is the adhesion of tear proteins, which provide anchoring points for bacterial colonization. A possible solution is the functionalization with an antimicrobial coating, though the latter may also lead to sight obstruction

Okara protein (OP) is a potential plant-based protein that is beneficial to human health. In this work, an alternating ultrasonic/alkali treatment method with non-continued cavitation and thermal energy output was used to extract protein (AUA-OP) from okara to enhance the functional properties of OP and improve the stability of OP-based emulsions. The purity of AUA-OP was greater than 80%. Compared

Dolomiaea costus, commonly known as Indian costus, is a medicinal plant from the Asteraceae family. The root and powder of costus have been widely used to treat various health conditions. The primary bioactive compounds in this plant are sesquiterpene lactones, particularly costunolide and dehydrocostus lactone. This study aimed to establish a rapid, environmentally friendly, and cost-effective method

The effects of integrated ultrasonic infrared frying (USIF) on the oil absorption of apple slices and the oil deterioration were studied with frequency of 28 and 40 kHz, respectively. Results showed that the heat transfer and moisture migration was accelerated by the integrated ultrasound in IF. The soluble Gal-A content and esterification degree of pectin was increased, the damages of pectin crystal

Water-in-water (w/w) emulsions, comprising aqueous droplets within another continuous aqueous phase, rely on a low interfacial tension for stability. Thus far, it has been challenging to control their size and stability without the use of stabilizers. In this study, we introduce a microfluidic technique that addresses these challenges, producing stable w/w emulsions with precisely controlled size and

Antarctic krill is a promising source of marine proteins with abundant biomass and excellent nutritional profile, but has poor technological properties. Ultrasonic treatment at power levels of 0, 100, 200, 300, 400 and 500 W was applied to improve the technological properties of Antarctic krill meat, and the changes in physicochemical properties of myofibrillar proteins (MPs) were investigated. The

The hypoxic and immunosuppressive tumor microenvironment (TME) remains a major obstacle to impede cancer immunotherapy. Here, we found that sononeoperfusion—a new effect of tumor perfusion enhancement induced by low mechanical index ultrasound stimulated microbubble cavitation (USMC)—ameliorated tumor tissue oxygenation and induced tumor vascular normalization (TVN). This TVN might be associated with

This study investigates the effects of multi-frequency ultrasound treatment on the quality of frozen dough. We analyzed frozen wheat dough comprehensively for texture, viscosity, rheology, and structural quality characteristics under multi-frequency ultrasound (20 kHz, 20/40 kHz, and 20/40/60 kHz) with different treatment times (10, 20, and 30 mins). The dough treated with multi-frequency ultrasound

The effect of multi-frequency ultrasound-assisted (20/28/40 KHz) lactic acid bacteria (LAB- Lacticaseibacillus casei, Lactiplantibacillus plantarum, Lacticaseibacillus paracasei, Lactobacillus acidophilus, and Lactobacillus helveticus) fermentation (mono and co-cultures) on the metabolic, structural, micromorphological, and sensorial properties of mulberry juice were evaluated. Results indicated that

Ultrasound has shown its benefits in the manufacturing processes of many pharmaceuticals and fine chemicals. This study focused on the reactive crystallization system of an aromatic amine and explored the potential uses of ultrasound in both batch and continuous modes. In batch experiments, we studied the effects of different sonication conditions including power, duration, and starting point on final

The Ni mesh was incorporated into the Cu/Sn58Bi/Cu bonding as a reinforcing skeleton to achieve an enhancement effect analogous to steel reinforcement in concrete. Ultrasonic-assisted soldering (UAS) improved the metallurgical bond among the solder, Ni mesh, and substrate. It facilitated the formation of (Cu, Ni)6Sn5 intermetallic compounds (IMCs) layers, increasing the joint strength. Observations

This research aimed to examine the effect of countercurrent ultrasound on extraction efficiency of cold brew coffee (CBC). The quality and flavor of CBC obtained by ultrasonic-assisted extraction (UE) were evaluated and compared with traditional extraction (TE). Meanwhile, the UE process was monitored in situ real-time using a near-infrared (NIR) spectrometer. The optimal UE parameters obtained by

Zinc-Manganese spinel ferrites (Zn1-xMnxFe2O4) are nowadays very attractive magnetic materials for cancer diagnostic and therapy. With the help of intense ultrasonic waves, sonochemical synthesis method was used to prepare stoichiometric and chemically homogenous nanoparticles by varying the manganese content. The crystal structure along with the size and shape of the as-prepared nanoparticles were

Developing innovative sonoreactors to enhance acoustic processing efficiency holds immense importance in the field of sonochemistry. Traditional immersed sonoreactors (TISs) mainly produce cavitation at the probe tip, with a relatively weak cavitation around the probe, resulting in posing challenges for high-efficiency cavitation treatment. Here we propose an acoustic black hole immersed sonoreactor

Bubble dynamics is paramount in comprehending the heat transfer mechanisms of flow boiling in the microchannel within ultrasonic field, which is regarded as a promising method to confront challenges of thermal management posed by microelectronic devices. Nevertheless, the impact of ultrasound on bubble behaviors and its underlying mechanisms remain largely unexplored. This study first delves into the

The persistence and toxicity of hazardous pollutants present in wastewater effluents require the development of efficient and sustainable treatment methods to protect water resources. In this study, the efficacy and efficiency of a novel combination of two advanced oxidation processes – sub-atmospheric-pressure plasma and hydrodynamic cavitation – were systematically tested for the removal of valsartan

The acid hydrolysis process was used to create novel millet starch-based nanoparticles from three different sources: sorghum, foxtail millet and pearl millet. An environment-friendly, risk-free ultrasonication technique was used for encapsulating beta carotene in starch nanoparticles to create nanocapsules that will shield the bioactivity of beta carotene in gastrointestinal conditions and increase

To address the delamination phenomenon during storage and flavor characteristics of Oyster protein hydrolysates (OPH). In this study, xylo-oligosaccharides (XOS) were selected to covalently graft with OPH through ultrasound-assisted Maillard reaction, and the effect of ultrasound-assisted Maillard reaction on the structure, functional properties, and flavor characteristics of OPH were investigated

The demand for rare and precious metals (RPMs), e.g. gold, is increasing, as these are used in the ever-increasing amount of electronics needed for technological development and digitalization. Due to their rarity, virgin mining of RPMs is becoming more difficult and expensive. At the same time, over 62Mt of e-waste is created globally each year. The high concentration of gold and other RPMs in e-waste

In this paper, a new type of antifreeze peptide was identified from the ultrasonic-assisted enzymolysis product of yak skin. First, the antifreeze peptides were obtained by ultrasonic-assisted enzymolysis of yak skin gelatin. The obtained peptides with 150 W ultrasound treatment could increase the survival rate of Lactobacillus plantarum from 16 % to 60 % after four freeze–thaw cycles. Then, the component

Ultrasonic and microwave extraction process has great prospects to convert food and agricultural waste from food industries to value-added goods. Also, this review extensively elaborates the utilization of ultrasonication and microwave extraction (US-MW) process for valorization of dairy waste extracted proteins into novel foods. Both of these extraction and processing techniques are considered as

Cancer immunotherapy has significant potential as a cancer treatment since it boosts the immune system and prevents immune escape to get rid of or fight cancers. However, its clinical applicability is still limited because of the low response rate and immune-related side effects. Recently ultrasound has been shown to alter the tumor immune microenvironment, enhance the effectiveness of other antitumor

Hydrogen removal from particle-reinforced Al composite is critical for preventing porosities near particle clusters and improving comprehensive material properties. This study investigated the effects of different argon flow schemes and power ultrasound on bubble dispersion in water. Based on similarity theory, the optimal argon flow scheme for ultrasonic-assisted argon (UAA) treatment was identified

The regulation of propellant combustion using ultrasonic waves is proposed. Under ultrasonic frequencies of 25–40 kHz, we systematically examined the combustion characteristics of Al particles, ammonium perchlorate (AP)/hydroxyl-terminated polybutadiene (HTPB) propellants, and Al-containing Al/AP/HTPB propellants. Ultrasonic treatment increased the ignition delay time of the Al particles by 48.3 %

The ultrasonic liquid phase exfoliation method has emerged as an essential research direction for graphene preparation due to its cost-effectiveness and ability to minimize defects. However, this method faces challenges related to processing throughput when scaled up for industrial production. In this study, industrial grade ultrasonic homogenizers with different frequencies and probe types were evaluated

Salted duck eggs are a popular food product, but their high salt content and uneven salt distribution can reduce acceptability. This study investigated the effects of pH-high-intensity ultrasound combined treatment on the salt-induced gelation properties of egg yolk granules. The results showed that the pH5 + 150 W treatment group exhibited the best physical and gelation properties, with the smallest

As a natural emulsifier, egg white protein (EWP) has great interfacial characteristics and high security, and has broad development prospects. This study explored the impact of ultrasound synergized citral (CI) treatment on the microstructure, molecular flexibility and emulsifying property of EWP, and predicted the interaction between CI and ovalbumin (the main protein in EWP) through molecular docking

Homogenization-circulating ultrasound in combination with an aqueous enzymatic pretreatment microwave-assisted extraction (HCUEPM) technique was successfully applied to extract kernel oil and essential oil from Litsea cubeba fruits. After screening the types and concentrations of enzymes, a 3 % pectinase aqueous solution was chosen. The Plackett–Burman design was used to screen eight parameters that

A significant amount of glycyrrhiza wastewater is generated in the cleaning process of glycyrrhiza. The wastewater contains polysaccharide, glycyrrhizic acid, liquiritin, and other polyphenols, which is expensive for cleanup and wastes medical resources. To reduce environmental pollution from glycyrrhiza wastewater and increase the resource usage efficiency of glycyrrhiza components. According to the

The industrial preparation of kudzu starch (KS) significantly reduces the remaining of flavonoids like puerarin (PU) in the product, weakening its biological activity and making pre-treatments on kudzu crucial. Ultrasonic technique, widely used for modifying biomolecules, can enhance nutrient interactions like those between starch and polyphenols in foods. Thus, a puerarin-kudzu starch (PKS) complex

Whey protein concentrates (WPCs) are gaining importance as a functional ingredient due to their high technological and functional properties and their diverse application in the food industry. In this study, Camel milk whey (CW) was separated from skimmed camel milk, then either spray-dried (SD) at 170, 185 and 200 °C, or treated by ultrasonication (US) (20 kHz) for 5, 10 and 15 min followed by freeze-drying

This study focuses on the extraction of bioactive compounds from date seeds using five polyol-based deep eutectic solvents (P-DESs) in combination with hybrid green extraction techniques, specifically microwave-assisted extraction (MAE), homogenization-assisted extraction (HAE), and ultrasound-assisted extraction (UAE). The optimization of these extraction techniques was achieved using P-DESs showing

Bacterial infections pose considerable health risks, emphasising the critical need for effective and biocompatible antibacterial drugs. Considerably, we developed an efficient antimicrobial system incorporating the combined potential of high-frequency ultrasound and antimicrobial drugs against bacterial infections. A ZnO–kaolinite (Kaol) composite with antibacterial properties was synthesised by growing

Most research on sonoluminescence and sonochemistry has been conducted at acoustic frequencies above ∼20 kHz. Consequently, mathematical models for the dynamics of acoustically-driven bubbles have hardly been examined in the audible frequency spectrum. Here, we develop a new hybrid modelling approach that combines the rigour of the advection–diffusion model whilst retaining the simplicity of a reduced-order

Centella asiatica has been known for its significant medicinal properties due to abundance of bioactive constituents like triterpenoids and flavonoids. Nevertheless, an appropriate solvent system and extraction technique is still lacking to ensure optimized extraction of bioactive constituents present in C. asiatica. Recently, scientists are more focused towards application of green sustainable extraction

Sonodynamic therapy (SDT) is a minimally invasive targeted cancer therapy that uses focused low-intensity ultrasound (<10 MPa, <10 W/cm2) to activate sonosensitizer drugs. Once activated, these chemical compounds generate reactive oxygen species (ROS) to damage and kill cancer cells. A Phase I clinical trial has shown promising results for treating glioblastoma with SDT. We hypothesize that the efficacy

Sea lettuce, or Ulva spp., dominates global algal biomass and significantly contributes to “green tides.”, representing a sustainable source for biomaterials. This study explores an innovative ultrasound-enzyme assisted extraction method with the novel Cellic® CTEC3 enzyme cocktail, applied for the first time in Ulva spp. succesfully enhancing ulvan release and extraction efficiency. Various processing

This study investigated the effect of ultrasound-assisted enzymatic extraction (UAEE) on the extraction efficiency, antioxidant activity, and structural properties of jujube polysaccharide (JPS), with hot water extraction (HWE), ultrasound-assisted extraction (UAE), and enzymatic-assisted extraction (EAE) serving as controls. Optimal extraction conditions were determined through a multi-index weighted

Chickpea protein isolate (CPI) is a promising dietary protein with the advantages of low allergenicity, easy digestion and balanced composition of essential amino acids. However, due to the thick skin of chickpeas, the extraction of CPI is challenging, resulting in lower efficiency of the alkaline extraction-isoelectric precipitation (AE-IEP) method. Therefore, the present study investigated the effect

Sonoporation has long been known to disrupt intracellular signaling, yet the involved molecules and pathways have not been identified with clarity. In this study, we employed whole transcriptome shotgun sequencing (RNA-seq) to profile sonoporation-induced gene responses after membrane resealing has taken place. Sonoporation was achieved by microbubble-mediated ultrasound (MB-US) exposure in the form