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Raman Spectral Feature Enhancement Framework for Complex Multiclassification Tasks Anal. Chem. (IF 6.7) Pub Date : 2024-12-20 Jiaqi Hu, Chenlong Xue, Ken Xiaokeng Chi, Junyu Wei, Zhicheng Su, Qiuyue Chen, Ziyu Ou, Shuxin Chen, Zhe Huang, Yilin Xu, Haoyun Wei, Yanjun Liu, Perry Ping Shum, Gina Jinna Chen
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Microneedle-Based Electrochemical Array Patch for Ultra-Antifouling and Ultra-Anti-Interference Monitoring of Subcutaneous Oxygen Anal. Chem. (IF 6.7) Pub Date : 2024-12-20 Jiaxi Liu, Jiang Liu, Yanyan Liang, Jiao Yang, Yongping Lin, Yingchun Li
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A Modern Framework for Analytical Procedure Development and Lifecycle Management Based on ICH Q14 Principles Anal. Chem. (IF 6.7) Pub Date : 2024-12-20 Max Eberle, Jamie T. Wasylenko, Drazen Kostelac, Sarah Kiehna, Adam Schellinger, Zhaorui Zhang, Jason D. Ehrick
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Advanced Mass-Spectra-Based Machine Learning for Predicting the Toxicity of Traditional Chinese Medicines Anal. Chem. (IF 6.7) Pub Date : 2024-12-20 Chen Jia, Xiaofang Li, Song Hu, Guohong Liu, Jiansong Fang, Xiaoxia Zhou, Xiliang Yan, Bing Yan
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miR-Cabiner: A Universal microRNA Sensing Platform Based on Self-Stacking Cascaded Bicyclic DNA Circuit-Mediated CRISPR/Cas12a Anal. Chem. (IF 6.7) Pub Date : 2024-12-20 Ruijia Deng, Jing Sheng, Zuowei Xie, Hongzhao Yang, Sha Yang, Shuang Xie, Xiaoqi Tang, Shuang Zhao, Haohao Dong, Ming Chen, Kai Chang
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TG-MS Analysis for Elemental Composition of Organic Matters and Their Structural Properties Anal. Chem. (IF 6.7) Pub Date : 2024-12-20 Lin Lin, Sasha Yang, Fuhong Zhang, Muxin Liu, Dong Liu, Lei Shi
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MWFormer: Estimation of Molecular Weights from Electron Ionization Mass Spectra for Improved Library Searching Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Qiong Yang, Hailiang Zhang, Yue Wang, Lin Tan, Ting Xie, Yufei Wang, Jia Long, Zixuan Guo, Zhimin Zhang, Hongmei Lu
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Introducing “Identification Probability” for Automated and Transferable Assessment of Metabolite Identification Confidence in Metabolomics and Related Studies Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Thomas O. Metz, Christine H. Chang, Vasuk Gautam, Afia Anjum, Siyang Tian, Fei Wang, Sean M. Colby, Jamie R. Nunez, Madison R. Blumer, Arthur S. Edison, Oliver Fiehn, Dean P. Jones, Shuzhao Li, Edward T. Morgan, Gary J. Patti, Dylan H. Ross, Madelyn R. Shapiro, Antony J. Williams, David S. Wishart
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Polyvalent Aptamers Structure-Mediated Fluorescent Aptasensor for the Early Diagnosis of Alzheimer’s Disease by Coupling with HCR and CRISPR-Cas System Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Xinyi Li, Bingjie Chen, Yaoyao Xie, Yi Luo, Dan Zhu, Lianhui Wang, Shao Su
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A–D–A Molecular Design Strategy Enabling Ultrasensitive NIR Vapor Sensing Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Wenxing Xu, Kangbo Zhen, Wancheng Bao, Zezong Shi, Xiuyun Jiang, Kai Qi, Wei Xu, Zhengqi Shen, Chunhui Li, Zhaohui Zhu, Huan Liu, Bo Wang, Qingguo He, Huizi Li, Jiangong Cheng, Xiang Ma, Yanyan Fu
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Electrochemiluminescence Detecting and Imaging of Yeast Metabolism Indicated by Endogenetic Co-reactant Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Jiancong Ni, Shengxiu Huang, Weiqiang Yang, Qiaoling Chen, Zhenyu Lin
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CRISPR/Cas12a-Enabled Amplification-Free Colorimetric Visual Sensing Strategy for Point-of-Care Diagnostics of Biomarkers Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Zhe Zhao, Qing Xiong, Yan Zhu, Cong Zhang, Zhixin Li, Zhonghui Chen, Ying Zhang, Xiaoyu Deng, Yingzhou Tao, Shaohua Xu
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Girard Derivatization-Based Enrichment Strategy for Profiling the Carbonyl Submetabolome in Biological Samples Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Xin Tao, Jia-Yue Liu, Jun-Yi Zhou, Jiang-Kun Dai, Zeyu Xiao, Hou-Kai Li, Jian-Bo Wan
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Aptamer-Based Activatable Tyramide Signal Amplification for Low-Background Detection of SARS-CoV-2 Nucleocapsid Protein Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Zhiyong Huang, Ziyan Du, Juan Li, Da Han, Jiaxuan He, Yunben Yang, Dan Wang, Yu Liang, Yunshan Yang, Ruizi Peng, Weihong Tan
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Electric Field Distribution in Bipolar Electrochemical Cells: Effects on the Wirefree Electrodeposition of Conducting Polymer Films Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Áine Brady, Robert J. Forster
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Pair-Soil-Spectra: An Approach for NIRS-Based Soil Total Nitrogen Content Detection with Feature Metrics in Cases of Small Sample Sizes Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Yueting Wang, Chunjiang Zhao, Zhen Xing, Mingyan Zhu, Lianglin Hao, Ke Wang, Juekun Bai, Hongwu Tian, Daming Dong
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Electrochemical Quantification of miRNA Based on Strain-Promoted Azide–Alkyne Cycloaddition Ligated Tetrahedral DNA Nanotags Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Yuzhu Ma, Tingting Wang, Xiaolin Qu, Ruhong Yan, Peng Miao
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Development of a Nanobody–Alkaline Phosphatase Fusion Protein for Detection of SARS-CoV-2 Spike Protein in a Fluorescence Enzyme Immunoassay Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Heng Liu, Qianling Su, Siliang Duan, Xianing Huang, Xiaomei Yang, Aiqun Liu, Shiquan Liu, Chun Xu, Xiaoling Lu
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Visual Detection of Methylglyoxal in Multiple Scenarios via NIR-Excitable Reversible Ratiometric Fluorescent Hydrogel Sensor Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Xiaohui Kang, Lanpeng Zhang, Wei Jia, Liang Yang, Changlong Jiang
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Differential Mobility Spectrometry Acoustic Ejection Mass Spectrometer System for Screening Isomerization-Mediating Enzyme Drug Targets Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Samad Bazargan, Patricia Dranchak, Chang Liu, James Inglese, John Janiszewski, Bradley B. Schneider, Thomas R. Covey
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An Entropy-Driven Multipedal DNA Walker Microsensor for In Situ Electrochemical Detection of ATP Anal. Chem. (IF 6.7) Pub Date : 2024-12-19 Hong Jiang, Xiao Liu, Dong Zhao, Yu-Kang Jia, Ya-Qin Wang, Wei Li, Zhao-Peng Liu, Ji-Dong Wang
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Electrochemical Behaviors of Ultramicro Triangular Pipettes Anal. Chem. (IF 6.7) Pub Date : 2024-12-18 Yutong Hua, Junjie Liu, Deyi Zhang, Jintao Deng, Chang Liu, Xianhao Zhang, Zhiwei Zhu, Huan Wang, Yuanhua Shao
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Transcending Resolution Limits in HPLC and Diffusion NMR Anal. Chem. (IF 6.7) Pub Date : 2024-12-18 Nouran A. Hamed, Alexandria K. Shread, Gareth A. Morris, Mathias Nilsson
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3D-Printable Rotary Valves for Low-Pressure Pneumatic and Fluidic Applications in Analytical Chemistry Anal. Chem. (IF 6.7) Pub Date : 2024-12-18 Tomas Drevinskas, Andrew Berg, Aaron C. Noell, Mauro S. Ferreira Santos, Maria F. Mora, Peter A. Willis
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A Novel Label-Free Method for Efficient Detection of Bisphosphonate Drug Dissolution Rates Using Surface-Enhanced Raman Spectroscopy Anal. Chem. (IF 6.7) Pub Date : 2024-12-18 Li Zhang, Junting Wang, Shuang Jiang, Zheng Feng, Yuanqiu Mu, Zhibin Wang, Chunli Gan, Xiaotong Wang, Yue Zhao, Huimin Yu, Chunjuan Yang, Yang Li
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SlipChip Enables the Integration of CRISPR-Cas12a and RPA for Fast and Stand-Alone HPV Detection Anal. Chem. (IF 6.7) Pub Date : 2024-12-18 Yin Zhao, Zheyu Li, Tao Li, Ruotong Rao, Jiang Zhu, Rui Hu, Guoyong Xu, Ying Li, Yunhuang Yang
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Advanced SERS Platform for Uniform and Reliable Molecular Detection Anal. Chem. (IF 6.7) Pub Date : 2024-12-18 Tiying Zhu, Zhiyang Pei, Xiaofei Zhao, Jing Yu, Baoyuan Man, Pingheng Tan, Zhen Li, Chao Zhang
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A Novel System for Simultaneous Real-Time Determination of 15N-Enriched Ammonia, Hydroxylamine, Nitrite, and Nitrate Anal. Chem. (IF 6.7) Pub Date : 2024-12-18 Jing Wei, Zheyan Zhou, Yunjie Zhang, Xiao Ma, Longfei Yu, Teng Wen, Jinbo Zhang, Qing Mu, Wenping Yuan
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Specific Response Assembly of 3D Space-Confined DNA Nanoaggregates for Rapid and Sensitive Detection of DNA Methyltransferase Anal. Chem. (IF 6.7) Pub Date : 2024-12-18 Jia-Hao Tang, Wei Liu, Mao-Hua Gao, Xian-Ming Guo, Yan-Mei Lei, Ying Zhuo
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Developing Multiple Media Approach to Investigate Reproducible Characteristic VOCs of Lung Cancer Cells Anal. Chem. (IF 6.7) Pub Date : 2024-12-18 Jijuan Zhou, Dianlong Ge, Yue Liu, Yajing Chu, Xiangxue Zheng, Yan Lu, Yannan Chu
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Manipulating Near-Infrared Absorption via Engineering Anisotropic Plasmonic Spiky Au Nanocubes for the Highly Efficient Dual-Response Immune Detection of T-2 Toxin Anal. Chem. (IF 6.7) Pub Date : 2024-12-18 Rui Shu, Kexin Wang, Meilin Wang, Sijie Liu, Jiayi Zhang, Ibrahim A. Darwish, Jianlong Wang, Daohong Zhang
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Advanced Ligase Chain Reaction Strategy to Generate a Circular DNA Walker for Electrochemiluminescent Detection of Single Nucleotide Polymorphism Anal. Chem. (IF 6.7) Pub Date : 2024-12-18 Lu Yan, Xiu-Li Tao, Qiao-Lin Chen, Wen Li, Ya-Qin Chai, Ruo Yuan, Yan-Mei Lei, Ying Zhuo
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Unmixing Autoencoder for Image Reconstruction from Hyperspectral Data Anal. Chem. (IF 6.7) Pub Date : 2024-12-17 Xuyang Liu, Chaoshu Duan, Wensheng Cai, Xueguang Shao
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Real-Time Monitoring of Metal Ions during the Molten Salt Electrolysis Process by Optical Emission Spectrometry Based on Microplasma Anal. Chem. (IF 6.7) Pub Date : 2024-12-17 Junhan Luo, Jingcui Liu, Qi Qing, Shuang Liu, Zhe Wang, Jing Chen, Yuexiang Lu
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Online Monitoring of the Processing of Traditional Chinese Medicine by Neutral Desorption Atmospheric Pressure Chemical Ionization Mass Spectrometry Anal. Chem. (IF 6.7) Pub Date : 2024-12-17 Zhendong Yu, Hui Li, Luyao Zhong, Wenshan Cui, Zhi-Liang Chen, Luqi Huang, Zidong Qiu, Rui Su, Jiaquan Xu
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Time-Resolved Levodopa Cascade Polymerization Tuned by Bimetallic MOF Fluorescent Nanozyme and Boric Acid for Butyrylcholinesterase Activity Dual-Mode Assay Anal. Chem. (IF 6.7) Pub Date : 2024-12-17 Qi Xu, Shuo Wang, Zhiwen Gan, Yongzhen Liu, Long Yu, Hong Cheng, Yuxiu Xiao
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Key Structure Parameters for Designing High-Performance Substrates of Surface-Enhanced Infrared Absorption Spectroelectrochemistry Anal. Chem. (IF 6.7) Pub Date : 2024-12-17 Jin Li, Qing-Ying Zhang, Zhendong Yan, Jian Li, Xing-Hua Xia
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Cellular and Intravital Nucleus Imaging by a D-π-A Type of Red-Emitting Two-Photon Fluorescent Probe Anal. Chem. (IF 6.7) Pub Date : 2024-12-17 De-Chen Duan, Gaowei Pan, Junru Liu, Hao Chen, Tao Xie, Ying Long, Fang Dai, Shengxiang Zhang, Bo Zhou
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Electrochemical Cell for Operando Grazing-Incidence X-ray Absorption Spectroscopic Studies of Low-Loaded Electrodes Anal. Chem. (IF 6.7) Pub Date : 2024-12-17 Maximilian Winzely, Adam H. Clark, Justus S. Diercks, Olga Safonova, Peter Rüttimann, Paul M. Leidinger, Sumant Phadke, Thomas J. Schmidt, Juan Herranz
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A New Optical Analysis System for Online Measurement of NO Temperature and Concentration in Combustion Processes Anal. Chem. (IF 6.7) Pub Date : 2024-12-17 Mu Li, Qiwen Zhou, Jie Gao, Rui Zhu, Fei Xie, Qiang Gao, Yungang Zhang
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Aggregation-Induced Electrochemiluminescence of Silica-Confined Tetraphenylethylene with Pd Nanocube-Loaded Co3O4 Nanosheets as a Coreaction Accelerator for Sensitive Bioanalysis Anal. Chem. (IF 6.7) Pub Date : 2024-12-17 Yu Du, Rui Feng, Tingting Wu, Hongying Jia, Bin Cai, Huangxian Ju, Qin Wei
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Integrated 3D-Printed Hollow Microneedle Array and Lateral Flow Immunoassay for Point-of-Care Wound Healing Monitoring Anal. Chem. (IF 6.7) Pub Date : 2024-12-17 Amadeo Sena-Torralba, Marc Parrilla, Ana Hernanz-Grimalt, Annemarijn Steijlen, Elena Ortiz-Zapater, Cristina Cabaleiro-Otero, Natividad López-Riquelme, Salvador Cerveró-Ferragut, Ángel Maquieira, Karolien De Wael, Sergi Morais
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Personalized Profiling of Lipoprotein and Lipid Metabolism Based on 1018 Measures from Combined Quantitative NMR and LC-MS/MS Platforms Anal. Chem. (IF 6.7) Pub Date : 2024-12-16 Siyu Zhao, Corey Giles, Kevin Huynh, Johannes Kettunen, Marjo-Riitta Järvelin, Mika Kähönen, Jorma Viikari, Terho Lehtimäki, Olli T. Raitakari, Peter J. Meikle, Ville-Petteri Mäkinen, Mika Ala-Korpela
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Permeability-Engineered Compartmentation System-Enabled Digital PCR (PECS-dPCR): A Digital Platform toward Multistep Biomolecular Assays Anal. Chem. (IF 6.7) Pub Date : 2024-12-16 Jie Li, Yanan Du, Qingyuan Shi, Long Chen, Xiuli Gao, Yifan Liu, Yuan Luo
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Bisulfite-Free and Quantitative Detection of DNA Methylation at Single-Base Resolution by eROS1-seq Anal. Chem. (IF 6.7) Pub Date : 2024-12-16 Fang-Yin Gang, Neng-Bin Xie, Min Wang, Shan Zhang, Tong-Tong Ji, Wei Liu, Xia Guo, Shu-Yi Gu, Bi-Feng Yuan
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Bioinspired Spatial Compartment of Substrate Molecules and Catalytic Counting Entities in Hierarchical MOFs Initiated for a Dual-Mode Glycoprotein Assay Anal. Chem. (IF 6.7) Pub Date : 2024-12-16 Yi Yang, Licheng Yu, Liang He, Pengli Bai, Xiwen He, Langxing Chen, Yukui Zhang
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Cyclic Olefin Copolymer-Based Fixed-Target Sample Delivery Device for Protein X-ray Crystallography Anal. Chem. (IF 6.7) Pub Date : 2024-12-16 Abhik Manna, Mukul Sonker, Domin Koh, Michael Steiger, Adil Ansari, Hao Hu, Isabel Quereda-Moraleda, Alice Grieco, Diandra Doppler, Daniele de Sanctis, Shibom Basu, Julien Orlans, Samuel L. Rose, Sabine Botha, Jose Manuel Martin-Garcia, Alexandra Ros
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High-Recovery Desalting Tip Columns for a Wide Variety of Peptides in Mass Spectrometry-Based Proteomics Anal. Chem. (IF 6.7) Pub Date : 2024-12-16 Eisuke Kanao, Shunsuke Tanaka, Ayana Tomioka, Kosuke Ogata, Tetsuya Tanigawa, Takuya Kubo, Yasushi Ishihama
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Improving Glycoproteomic Analysis Workflow by Systematic Evaluation of Glycopeptide Enrichment, Quantification, Mass Spectrometry Approach, and Data Analysis Strategies Anal. Chem. (IF 6.7) Pub Date : 2024-12-16 Zhenyu Sun, T. Mamie Lih, Jongmin Woo, Liyuan Jiao, Yingwei Hu, Yuefan Wang, Hongyi Liu, Hui Zhang
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Zinc-Organic Gel with Self-Catalysis-Enhanced Electrochemiluminescence as an Emitter for the Evaluation of Liver Cancer Markers Anal. Chem. (IF 6.7) Pub Date : 2024-12-16 Linlei Liu, Yuanqi Xu, Bihui Fan, Haijun Wang, Yue Zhang, Xingrong Tan, Yaqin Chai, Ruo Yuan
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Single-Particle ICP-TOFMS Analysis of Aerosol Particulate Matter Released by Fused Deposition Modeling 3D Printers Anal. Chem. (IF 6.7) Pub Date : 2024-12-16 Tristen L. Taylor, Madison Strait, Alexander Gundlach-Graham
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Fluorescent Probe for the pH-Independent Rapid and Sensitive Direct Detection of Urease-Producing Bacteria Anal. Chem. (IF 6.7) Pub Date : 2024-12-16 Werner C. Albrich, Christian R. Kahlert, Susanne Nigg, Luciano F. Boesel, Giorgia Giovannini
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Analytical Challenges and Strategies for Particle-Based Analysis of Airborne Micro(nano)plastics in Size-Fractionated Samples Using Microscopy, SEM/EDX, and Raman Spectroscopy Anal. Chem. (IF 6.7) Pub Date : 2024-12-16 Parisa Akbari Dana, Eftade O. Gaga, Kadir Gedik
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Illumination of Hydroxyl Radical Generated in Cells during Ferroptosis, Arabidopsis thaliana, and Mice Using a New Turn-On Near-Infrared Fluorescence Probe Anal. Chem. (IF 6.7) Pub Date : 2024-12-13 Qiuyue Wang, Haiyang Ji, Yitong Hao, Dongli Jia, Hongyu Ma, Changying Song, Honglan Qi, Zhao Li, Chengxiao Zhang
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Biofluorometric Acetone Gas Sensor of Sub-ppbv Level Sensitivity Anal. Chem. (IF 6.7) Pub Date : 2024-12-13 Kenta Iitani, Naohiro Ishizuki, Yuka Matsuhashi, Kumi Yokota, Kenta Ichikawa, Koji Toma, Takahiro Arakawa, Yasuhiko Iwasaki, Kohji Mitsubayashi
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Gold Nanoparticle Detection with Two-Photon Excitation Fluorescence Lifetime Imaging of NAD(P)H in Cancer Cells: An Analytical Approach to Separate Nanoparticle and NAD(P)H Signals Anal. Chem. (IF 6.7) Pub Date : 2024-12-12 Mahshid Ghasemi, Amy Holmes, Tyron Turnbull, Ivan Kempson
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Harnessing Demethylase-Regulated Catalytic DNA Circuit for In-Situ Investigation of the Regulatory Connection with MicroRNA Anal. Chem. (IF 6.7) Pub Date : 2024-12-12 Guangqin Liu, Yifei Wang, Yuqiu He, Mengdi Yu, Xiaoqing Liu, Fuan Wang
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Point-of-Care Diagnosis of Tuberculosis Using a Portable Nucleic Acid Test with Distance-Based Readout Anal. Chem. (IF 6.7) Pub Date : 2024-12-12 Tianyu Dong, Liwen Qin, Zhiyin Wang, Chen Fan, Chenlan Shen, Pin Feng, Qingquan Kong, Bowen Ke, Binwu Ying, Feng Li
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Detecting Colorectal Neoplasia Using Specific Fecal Fluorogenic Protease-Sensitive Substrates: A Pilot Study Anal. Chem. (IF 6.7) Pub Date : 2024-12-12 Roza C. M. Opperman, Sofie Bosch, Kamran Nazmi, Floris J. Bikker, Henk S. Brand, Connie R. Jimenez, Tim G. J. de Meij, Evelien Dekker, Nanne K. H. de Boer, Wendy E. Kaman
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Autonomous Sweating Wearable Platform for Bilirubin Sensing Based on Thermal Stimulation Anal. Chem. (IF 6.7) Pub Date : 2024-12-12 Zhongzeng Zhou, Jing Wang, Tailin Xu, Xueji Zhang