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Polystyrene microplastics exacerbate acetochlor-induced reproductive toxicity and transgenerational effects in zebrafish Aquat. Toxicol. (IF 4.1) Pub Date : 2024-12-11 Yang Wang, Chaofan Ma, Zenglong Chen, Yinping Guo, Yuan Jing, Xiaolei Chen, Hongwu Liang
Microplastic (MPs) can adsorb co-existing pollutants, and alter their behavior and toxicity. Meanwhile, amide herbicides like acetochlor (ACT) are widely used in agriculture, with potential endocrine-disrupting effects that raise ecological concerns. The aim of this research was to examine the effects of MPs on the reproductive endocrine disruption caused by ACT and the effects of maternal transmission
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Tributyl phosphate inhibits neurogenesis and motor functions during embryonic development in zebrafish Aquat. Toxicol. (IF 4.1) Pub Date : 2024-12-08 Gourav Chakraborty, Bhagyashri Joshi, Kedar Ahire, Chinmoy Patra
Tributyl phosphate (TBP), an organophosphate ester (OPE), is heavily used as a solvent in chemical industries, a plasticizer, and to extract radioactive molecules. Thus, widespread uses of TBP in industrialized countries led to the release of TBP and its metabolites, dibutyl phosphate (DBP) and monobutyl phosphate (MBP), in the environment and were detected in human samples. Accumulating these OPEs
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Histopathological and histochemical analysis of the digestive tract of adult horseshoe crabs under mercury stress Aquat. Toxicol. (IF 4.1) Pub Date : 2024-12-08 Wanling Zhang, Mujiao Xie, Xiaohai Chen, Ziwei Ying, Yuyuan Bao, Yang-Guang Gu, Xiaoyong Xie
Mercury (Hg) contamination is a major environmental concern that continuously impacts marine organisms, including the mangrove horseshoe crab (Carcinoscorpius rotundicauda). As a vulnerable species, C. rotundicauda holds significant ecological and evolutionary value, making it particularly susceptible to Hg pollution and deserving of focused conservation efforts. This study presents the first comprehensive
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Multigenerational effects of virgin and sampled plastics on the benthic macroinvertebrate Chironomus riparius Aquat. Toxicol. (IF 4.1) Pub Date : 2024-12-08 Riccardo Sbarberi, Stefano Magni, Benedetta Ponti, Erica Tediosi, Maria Chiara Neri, Andrea Binelli
Although sediments are important reservoirs of plastics, most of the ecotoxicological studies on these contaminants are focused on the organisms living in the water column, while only a smaller number of evidence concerns the plastic impact on benthic species. Therefore, this study compared the multigenerational effects on the sediment-dwelling midge Chironomus riparius exposed to both virgin polystyrene
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The detrimental effects and mechanisms of Orlistat in disrupting energy homeostasis and reproduction in Daphnia magna Aquat. Toxicol. (IF 4.1) Pub Date : 2024-12-07 Zhihua Ni, Xinling Tian, Wenbo Zhao, Wenkai Hu, Jinghua Lv, Xiaoli Sun, Yajie Zhang, Yiwen Zhang, Yuming Zhang, Baoku Li, Fengsong Liu
Orlistat (ORL) has been employed as an anti-obesity pharmaceutical for several decades. Given its low absorption rate, the majority of administered ORL is excreted into the environment with feces. It is crucial to collect scientific information regarding the possible ecological risks associated with ORL. Here, the effects of ORL on Daphnia magna were evaluated using a 21-day chronic test at concentrations
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Acute and chronic toxicity of cationic polyquaterniums of varying charge density and molecular weight to Daphnia magna and Ceriodaphnia dubia Aquat. Toxicol. (IF 4.1) Pub Date : 2024-12-06 Jessica L. Brill, Anna Magdalene Brun Hansen, Hope Woods, Kristin A. Connors, Hans Sanderson, Scott E. Belanger
Cationic polymers have the unique ability to neutralize negative charge with practical applications in personal care products, such as shampoos, conditioners, contact lens solutions, and as flocculants in wastewater treatment processes. Cationic polymers are a diverse class of materials varying in structural composition, cationic charge density (CD), and molecular weight (MW). In this study, we investigated
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Exploring the combined toxicity of boron nitride nanosheets, cadmium and natural organic matter on Daphnia magna Aquat. Toxicol. (IF 4.1) Pub Date : 2024-12-03 Gabriela Helena da Silva, Jing Ji, Marcella Torres Maia, Davide Mattia, Diego Stéfani Teodoro Martinez
The increase in anthropogenic activities has led to the release of numerous chemicals and pollutants into aquatic ecosystems, raising significant concerns for water quality and health. Among the emerging issues is the interaction between pollutants and nanomaterials (mixture effects). In this work, it was studied the combined toxicity of boron nitride nanosheets (BNNS) and cadmium (Cd2+) incorporating
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Long-term exposure to sediment-associated antidepressants impacts life-history traits in an estuarine deposit-feeding worm Aquat. Toxicol. (IF 4.1) Pub Date : 2024-12-01 Martina Santobuono, Wing Sze Chan, Elettra D´Amico, Henriette Selck
Hydrophobic pollutants, such as the antidepressant sertraline (SER), tend to sorb to particles in the water column and subsequently accumulate in the sediment. Long-term exposure to these pollutants may significantly affect sediment-dwelling organisms´ fitness and behavior. To address this knowledge gap, we investigated the impact of chronic exposure to a range of environmentally relevant and higher
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The enzymatic and transcriptional adverse effects of hull in-water cleaning discharge on juvenile rockfish (Sebastes schlegeli) Aquat. Toxicol. (IF 4.1) Pub Date : 2024-12-01 Seong Hee Mun, Kwang-Min Choi, Dongju Shin, Moonkoo Kim, Taekhyun Kim, Dae-Jung Kim, Jee-Hyun Jung
The hull in-water cleaning (IWC) process creates chemical contaminants, including antifouling paint particle mixtures that are directly discharged into the coastal environment. Recent attention has also been paid to the international regulation of ship hull cleaning discharges in environmental media. However, few studies have investigated the adverse effects or toxic pathways on resident marine species
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TBBPA caused multiple intestinal injuries via ROS/NF-κB signal in common carp Aquat. Toxicol. (IF 4.1) Pub Date : 2024-12-01 Man Qian, Yuan Geng, Jing-jing Wang, Hong-ru Wang, Ji-long Luo, Xue-jiao Gao
Tetrabromobisphenol A (TBBPA) is an aquatic environment's prevalent pollutant, posing a great threat to the health of aquatic animals. The intestine is a key organ for nutrient absorption as well as an important barrier to prevent pollutants from invading the body of fish. Exploring the effects of pollutants on the intestine is of great significance for maintaining fish health. Therefore, the purpose
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A multi-comprehensive approach to assess the responses of the Mediterranean mussel Mytilus galloprovincialis (Lamarck, 1919) to a simulation of a diesel-oil mixture spill Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-30 F. Bertini, V. Catania, L. Scirè Calabrisotto, M. Dara, L. Bisanti, C. La Corte, M. Staropoli, D. Piazzese, M.G. Parisi, D. Parrinello, M. Cammarata
Oil spills are a major cause of pollution impacting marine ecosystems. In this work, the effects of short-term exposure to three different concentrations of a hydrocarbon mixture (HC), that simulated the action of such an event, were investigated on Mytilus galloprovincialis specimens. Physiological effects were measured using a battery of biomarkers consisting of cellular activity (phagocytosis),
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Effect of functional groups of polystyrene nanoplastics on the neurodevelopmental toxicity of acrylamide in the early life stage of zebrafish Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-25 Haohan Yang, Linghui Kong, Zhuoyu Chen, Jun Wu
Polystyrene nanoplastics (PS NPs) and acrylamide (ACR), both emerging contaminants, have been found to be related to neurotoxicity. However, the effects of PS NPs on ACR-induced neurodevelopmental toxicity remain unclear. In this study, anionic carboxyl polystyrene nanoplastics (PS NPs-COOH), cationic amino polystyrene nanoplastics (PS NPs-NH2) and unmodified PS NPs were selected to investigate their
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Unlocking the combined impact of microplastics and emerging contaminants on fish: A review and meta-analysis Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-25 Weiming Wu, Rupeng Du, Zhuoyun Chen, Weiwen Li, Xiaomei Huang, Zhong Pan
Microplastics (MPs) possess unique adsorptive properties that render their surfaces prone to absorbing other contaminants. When interacting with these emerging contaminants, MPs may have unpredictable negative impacts on fish. Prior studies have primarily concentrated on the impact of single contaminants, while investigations into combined pollution have not received adequate attention. Therefore,
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Glyphosate and glyphosate-based herbicides induce Poecilia reticulata to maintain redox equilibrium during and after coexposure to iron oxide nanoparticles (y-Fe2O3) Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-24 João Marcos de Lima Faria, Mariana Morozesk, Iara da Costa Souza, Victória Costa da Silva, Luiz Arthur Mendes Bataus, Simone Maria Teixeira de Sabóia-Morais, Marisa Narciso Fernandes
Iron oxide nanoparticles (IONPs) are being increasingly recognized as viable materials for environmental remediation due to their capacity to adsorb contaminants such as glyphosate (GLY) on their surfaces. Nevertheless, the ecotoxicological implications of IONPs associated with GLY necessitate thorough evaluation to ascertain the safety of such remediation strategies. In this context, the present investigation
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Establishment of a cell culture from Daphnia magna as an in vitro model for (eco)toxicology assays: Case study using Bisphenol A as a representative cytotoxic and endocrine disrupting chemical Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-23 Sreevidya CP, Manoj Kumar TM, Soumya Balakrishnan, Suresh Kunjiraman, Manomi Sarasan, Jason T. Magnuson, Jayesh Puthumana
Bisphenol A (BPA) is a widely used industrial compound found in polycarbonate plastics, epoxy resin, and various polymer materials, leading to its ubiquitous presence in the environment. The toxicity of BPA to aquatic organisms has been well documented following in vivo exposure scenarios, with known cytotoxic and endocrine-disrupting effects. As such, BPA was used in this study as a well-characterized
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Characteristics and potential human health risks of Paralytic Shellfish Toxins identified in eight species of bivalves from South Yellow Sea Mudflat Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-23 Cheng Ding, Jinling Wu, Qingyuan Guo, Jiaxuan Luan, Kai Yang, Zhaoxia Li, Xuan Li, Jianwei Yu, Feng Liang, Bairen Yang, Tianming Chen
The consumption of bivalves contaminated with paralytic shellfish toxins (PSTs) poses a serious risk to human health. However, the presence of PSTs in bivalves from the South Yellow Sea Mudflat remains unclear. This study comprehensively examined the characteristics and potential health risks of PSTs in eight species of bivalves from the South Yellow Sea Mudflat across four seasons. Typical PSTs, including
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Maternal Daphnia magna exposure to the antidepressant sertraline causes molting disorder, multi-generational reproductive and serotonergic dysfunction Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-23 Chenglong Dong, Liqiang Wang, Nikolai Barulin, Juan José Alava, Shaoquan Liu, Dongmei Xiong
Sertraline, one of the most commonly used antidepressants, has exhibited a progressively escalating trend in usage over the course of the last decades years, which have been exacerbated by the COVID-19 pandemic. Here, this study assessed the transgenerational effects of sertraline on the aquatic microcrustacean Daphnia magna, a parthenogenetic model species. The parental D. magna (G0) were exposed
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Derivation of toxicity parameters from field data: Analysis of lake zooplankton species responses to metals and acidity Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-19 E. Tipping, W. Keller, B.A. Edwards, S. Lofts
The WHAM-FTOXβ model describes the toxic effects of mixtures of protons and metal cations towards biological species, using a set of intrinsic parameters for the cations (αH, αM*) and a sensitivity parameter (β) for each species. We applied the model to extensive water chemistry and zooplankton species occurrence data for four lakes contaminated with acidity and metals (Al, Ni, Cu, Zn) at Sudbury,
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Integration of physiology, microbiota and metabolomics reveals toxic response of zebrafish gut to co-exposure to polystyrene nanoplastics and arsenic Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-19 Guoxin Li, Min Lv, Haitao Yu, Heng zhang, Dandan Zhang, Qingsong Li, Lei Wang, Yicheng Wu
Both nanoplastic (NP) particles and arsenic (As) are widespread in aquatic environments and pose a combined risk of exposure to aquatic organisms. How the gut of aquatic organisms responds to combined risk of exposure is still unclear. In this study, zebrafish (Danio rerio) were subjected to three distinct As stress environments: only As group (10 μg/L), and As combined with different concentrations
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Effects of perfluoroalkyl acids on nitrogen release, transformation and microbial community during the debris decomposition of Alisma orientale and Iris pseudacorus Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-19 Xiaoqing Li, Zulin Hua, Jianyun Zhang, Junliang Jin, Yifan Wang
The release of nutrients into water during debris decomposition is a serious concern, leading to severe environmental pollution. To understand the effects of extensively present emerging contaminants (such as perfluoroalkyl acids (PFAAs)) on the nitrogen (N) release and transformation, the concentration dynamics of different N species in surrounding water and changes in microbial communities on biofilm
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The role of chorion integrity on the bioaccumulation and toxicity of selenium nanoparticles in Japanese medaka (Oryzias latipes) Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-19 Hongxing Chen, Melissa Chernick, Wu Dong, Lingtian Xie, David E. Hinton
Selenium nanoparticles (nano-Se) have a wide range of biomedical and agricultural applications. However, there is little information on the potential toxicity of nano-Se once it enters the environment, particularly in fish. The first line of defense from contaminants that embryonic fish have is the chorion, but the degree to which the chorion protects the developing embryo is unknown. Japanese medaka
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Effects of steroid hormones and their mixtures on western mosquitofish (Gambusia affinis) Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-18 Chen-Si Wang, Guo-Yong Huang, Dong-Qiao Lei, Guang-Guo Ying
Steroid hormones, including estrone (E1), androstadienedione (ADD), and androstenedione (AED), are prevalent in aquatic ecosystems and pose ecological risks due to their disruptive influence on fish populations. However, little consideration has been given to the endocrine disrupting effects of fish exposed to complex mixtures of hormones in the real world. In this study, adult female western mosquitofish
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Impacts of nanopolystyrene and/or phoxim exposure at environmentally relevant concentrations on the intestinal histopathology, intestinal microbiota, and metabolome in Eriocheir sinensis Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-18 Shuquan Ding, Shunli Che, Mengting Huang, Yuan Ma, Longteng Shen, Jianbin Feng, Xilei Li
Nanopolystyrene (NP) pollution in aquatic environments has become an increasing concern. Phoxim (PHO), one of the major organophosphorus pesticides, has also been detected in aquatic environments, posing serious health risks to crustaceans. This study aimed to assess the detrimental effects of NP and/or PHO exposure at environmentally relevant concentrations on the intestinal histopathology, intestinal
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Uptake, removal and trophic transfer of fluorescent polyethylene microplastics by freshwater model organisms: the impact of particle size and food availability Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-14 Ning Gong, Zhiyuan Wang, Xiaofan Wang, Kuishuang Shao
As an emerging contaminant, microplastics (MPs) are widely distributed in freshwater ecosystems and pose potential threats to aquatic organisms, attracting significant attention from both the scientific community and the general public. However, there is still uncertainty regarding the mechanisms of MPs transfer within aquatic biota and how particle size and food availability influence their transport
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Integrated physiological, energy metabolism, and metabonomic responses indicate the stress response in the hepatopancreas of Litopenaeus vannamei to nitrite stress Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-13 Yafei Duan, Guowei Zhong, Meng Xiao, Yukai Yang, Yun Wang, Yuxiu Nan
Nitrite is a toxic substance found in rearing water that affects shrimp health. The hepatopancreas is an important digestive, immune, and metabolic organ in the shrimp. In this study, shrimps (Litopenaeus vannamei) were separately exposed to 1 and 5 mg/L nitrite stress for 48 h, and the toxicity of nitrite in the hepatopancreas was explored by integrating histology, physiological indicators, energy
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Fipronil exposure alters oxidative stress responses of Nile tilapia (Oreochromis niloticus) to acute moderate hypoxia Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-12 Priscila Leocádia Rosa Dourado, Danilo Grunig Humberto da Silva, Thiago Caique Alves, Eduardo Alves de Almeida
Acute hypoxia is known to increase the generation of reactive oxygen species (ROS), leading to modulation in antioxidant defenses. Pollutant exposure can potentiate ROS generation during hypoxic events and impair antioxidant defenses, increasing the susceptibility of hypoxia-tolerant fishes, such as the Nile tilapia (Oreochromis niloticus), to oxidative stress. The purpose of this study was to evaluate
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Adverse effects of glyphosate-based herbicide on hatching rate, morphological alterations, and acetylcholinesterase (AChE) expression in golden apple snail eggs Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-12 Phochit Nanthanawat, Wilaiporn Insuwan, Witchuda Prasatkaew, Jakkaphun Nanuam, Panomsak Meemon, Chutima Thanomsit
This research investigated the effects of glyphosate herbicide on golden apple snail (Pomacea canaliculata) eggs, focusing on hatching rates, morphological changes, and acetylcholinesterase (AChE) expression to explore its potential as a biomarker of exposure. Additionally, key bioactive components in golden apple snail eggs were characterized. The study demonstrated that glyphosate toxicity increased
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Trophic transfer effects of PS nanoplastics and field-derived nanoplastics in the freshwater clam Corbicula fluminea Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-10 Oihana Latchere, Isabelle Métais, Hanane Perrein-Ettajani, Magalie Lemoing, Agnès Feurtet-Mazel, Patrice Gonzalez, Guillemine Daffe, Julien Gigault, Charlotte Catrouillet, Amélie Châtel, Magalie Baudrimont
Plastic pollution is of global concern. Many studies investigated the effect of micro and nanoplatics towards aquatic organisms. However, relatively few studies were assessed on freshwater organisms. Another aspect of this pollution is the impact of trophic transfer on plastic distribution and on food chain in order to evaluate its potential risk towards environmental and human health. In this context
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Chemical-defensome and whole-transcriptome expression of the silverside fish Basilichthys microlepidotus in response to chronic pollution in the Maipo River basin, Central Chile Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-09 Jorge Cortés-Miranda, David Veliz, Noemí Rojas-Hernández, Ciro Rico, Catalina Gutiérrez, Caren Vega-Retter
Pollution is a major global concern affecting biodiversity, particularly of freshwater species. Populations have developed mechanisms to deal with pollution, such as the chemical defensome, which is a set of genes involved in maintaining internal stability. Pollution significantly affects the Maipo River basin in Chile. This area is home to the endemic silverside fish Basilichthys microlepidotus, whose
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Nanoplastics and bisphenol A exposure alone or in combination induce hepatopancreatic damage and disturbances in carbohydrate metabolism in the Portunus trituberculatus Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-08 Xiaotian Wang, Shangjie Zhou, Yutong Huang, Pengfei Chu, Long Zhu, Xiaocong Chen
Bisphenol A (BPA) is a widely found endocrine-disrupting chemical (EDC). Nanoplastics (NPs) represent a novel environmental pollutant, and the combined toxicity of these pollutants on the hepatopancreas of marine arthropods is understudied. To investigate the potential risks associated with co-exposure to BPA and NPs on the hepatopancreas, Portunus trituberculatus was treated with 100 μg/L BPA, 104
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Proanthocyanidins mitigate the toxic effects in loach (Misgurnus anguillicaudatus) exposed to phenanthrene via Nrf2/NF-κB signaling pathway Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-08 Qiongya Fang, Ke Li, Xinyu Zhang, Xiaorui Liu, Siqi Jiao, Li Sun, Min Li, Guiqin Wang, Yidi Kong
Phenanthrene (PHE) is a typical polycyclic aromatic hydrocarbon compound that is ubiquitous in the environment and accumulates in aquatic products, thereby posing a risk to food safety. Oligomeric proanthocyanidins (OPC) is widely distributed powerful antioxidants with potent antioxidant and anti-inflammatory properties. This study aimed to evaluate the alleviating effects of dietary OPC on oxidative
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Establishment of a cell culture from the frog Leptodactylus fuscus as a model for (eco)toxicological assays Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-06 Yure Jefferson da Cruz do Nascimento, Danilo Serrão Moutinho, Cesar Martins, Adauto Lima Cardoso, Lílian Lund Amado
Leptodactylus fuscus is a frog species widely distributed in the Neotropical region, occurring in several biomes, which makes it a potential biomonitor of environmental conditions. To advance the establishment of this species in this field, we developed a fibroblast-like cell line derived from the digits of the forelimbs (LFUfd) and evaluated its response to possible environmental stressors. An adult
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An adverse outcome pathway approach linking retinoid signaling disruption to teratogenicity and population-level outcomes Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-05 Audrey Phan, Aleksandra Sokolova, Klara Hilscherova
Recent research efforts in endocrine disruption have focused on evaluating non-EATS (estrogen, androgen, thyroid, and steroidogenesis) pathways. Retinoid signaling disruption is noteworthy because of its teratogenic effects and environmental relevance. However, current environmental risk assessments are limited in their ability to evaluate impacts on individuals and populations. This study characterizes
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Elucidation of molecular mechanisms involved in tadpole toxicity employing QSTR and q-RASAR approach Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-02 Kabiruddin Khan, Gopala Krishna Jillella, Agnieszka Gajewicz-Skretna
Tadpoles, as early developmental stages of frogs, are vital indicators of toxicity and environmental health in ecosystems exposed to harmful organic compounds from industrial and runoff sources. Evaluating each compound individually is challenging, necessitating the use of in silico methods like Quantitative Structure Toxicity-Relationship (QSTR) and Quantitative Read-Across Structure-Activity Relationship
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Bioaccumulation and biochemical impact of polyethylene terephthalate microplastics in Cipangopaludina chinensis: Tissue-specific analysis and homeostasis disruption Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-02 Lanjin Fang, Shuangshuang Wang, Xingbin Sun, Kejing Wang
Microplastics are a novel pollutant that adversely affect freshwater benthic organisms. However, few studies have investigated the mechanism underlying the bioaccumulation and the toxicity of microplastics. In this study, microplastics bioaccumulation of wild Cipangopaludina chinensis in the Songhua River were utilized, and a 28-day aquatic toxicity test was performed to determine the effects of exposure
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Ion-exchange chromatography in the assessment of environmental pollution with chlortetracycline Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-02 Łukasz Sikorski, Agnieszka Bęś, Elżbieta Karetko-Sikorska, Wojciech Truszkowski, Katarzyna Tomaszewska
Chemical substances such as drugs pose a threat to the environment. One of the substances recorded in soil and water is chlortetracycline, an antibiotic used in veterinary medicine. Plants exposed to such xenobiotics show changes in the content of biogenic amines. An analytical technique - ion exchange chromatography is used to assess their content. The occurrence of these active compounds is used
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Enhancing eco-sensing in aquatic environments: Fish jumping behavior automatic recognition using YOLOv5 Aquat. Toxicol. (IF 4.1) Pub Date : 2024-11-01 Kaibang Xiao, Ronghui Li, Senhai Lin, Xianyu Huang
Contemporary research on ichthyological behavior predominantly investigates underwater environments. However, the intricate nature of aquatic ecosystems often hampers subaqueous observations of fish behavior due to interference. Transitioning the observational perspective from subaqueous to supra-aquatic enables a more direct assessment of fish physiology and habitat conditions. In this study, we utilized
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Chronic toxic effects of chloroxylenol exposure on Rana chensinensis: Insights from endochondral ossfication Aquat. Toxicol. (IF 4.1) Pub Date : 2024-10-30 Yue Zhang, Zhaoyang Jiang, Xinyi Li
Chloroxylenol (para‑chloro-meta-xylenol, PCMX), is a widely used antimicrobial agent and can remain in the aquatic environment. Although toxicity studies related to PCMX on the aquatic animals like zebrafish and Brachionus koreanus have been reported, there are few reports in the ecological risk of amphibians. In this study, the toxicity of different concentration (143, 14.3, 1.43 μg/L) of PCMX treatments
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Evaluating the impact of the combined acute toxicity of iron (Fe) and microplastics on Namalycastis jaya Aquat. Toxicol. (IF 4.1) Pub Date : 2024-10-29 Sakthinarenderan Saikumar, Ravi Mani, Swedha Ganesan, Mirunalini Ganesan
The rising concern over heavy metals (HMs) and microplastics (MPs) pollution in marine ecosystems, primarily driven by anthropogenic activities, poses significant threats to ecological health. Understanding the combined exposure of HMs and MPs aids in toxicity assessment. In this study, we examined the combined effects of polystyrene microplastics (MPs) and iron (Fe) on oxidative stress, bioaccumulation
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Ocean acidification aggravates the toxicity of deltamethrin in Haliotis discus hannai: Insights from immune response, histopathology and physiological responses Aquat. Toxicol. (IF 4.1) Pub Date : 2024-10-29 Xiaojing Lv, Qinyou Deng, Lizhu Chen, Xin Wang, Yijing Han, Guiqing Wu, Yongliang Liu, Haiyue Sun, Xuan Li, Jinxia He, Xiangquan Liu, Dinglong Yang, Jianmin Zhao
Ocean acidification (OA) and other environmental factors can collectively affect marine organisms. Deltamethrin (DM), a type II pyrethroid insecticide, has been widely detected in coastal and estuarine areas, while little attention has been given to the combined effects of DM and OA. In this study, Haliotis discus hannai was exposed to three pH levels (8.1, 7.7 and 7.4) and three DM nominal concentrations
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Appraisal of a synthetic preservative, Quaternium – 15, effect on three model organisms: new insight on environmental risks Aquat. Toxicol. (IF 4.1) Pub Date : 2024-10-29 Giorgia Zicarelli, Federica Impellitteri, Caterina Faggio, Jana Blahova, Barbora Riesova, Renata Hesova, Pavla Lakdawala
After the COVID-19 pandemic, the use of quaternary ammonium compounds increased exponentially due to their efficacy as antimicrobials, stabilizers and disinfectants. Among these, Quaternium-15 is a preservative used in the formulation of a variety of personal care products. The increased use of this substance and the resulting persistence in wastewater treatment systems, which are unable to completely
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Impacts of paternal transmission of PCBs and global warming on the evolution of pace-of-life syndrome (POLS) during the early life stages of a cold stenothermic fish (Arctic charr) Aquat. Toxicol. (IF 4.1) Pub Date : 2024-10-28 Emilie Réalis-Doyelle, Jean Guillard, Romane Morati, Nathalie Cottin, Stéphane Reynaud, Emmanuel Naffrechoux
In the context of strong historical and climate anthropological pressure, we studied the impact of paternal transmission of PCBs on offspring of the stenothermic salmonid, Artic charr. Indeed, the transgenerational effects of maternal transmission are widely studied, unlike the paternal effect, which is often limited to epigenetic impacts. The study aims to test the effects of temperature and PCBs
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The effect of cortisone on female zebrafish (Dania rerio): Reducing reproductive capacity and offspring survival rate Aquat. Toxicol. (IF 4.1) Pub Date : 2024-10-28 MeiXin Ye, JinLin Yang, ZiPing Cai, JunHao Wu, Wenting Xiong, LiPing Hou
Cortisone is a naturally occurring corticosteroid hormone known for its wide range of anti-inflammatory and immunosuppressive effects, and it is commonly found in various aquatic environments. Previous reports have shown that cortisone can have significant negative impacts on fish; however, its specific effects on fish reproduction have not been thoroughly investigated. In this study, female adult
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Effects of ammonia exposure and post-exposure recovery in pacific white shrimp, Litopenaeus vannamei: Histological, physiological and molecular responses Aquat. Toxicol. (IF 4.1) Pub Date : 2024-10-28 Lanting Lin, Hongbiao Zhuo, Yuan Zhang, Jinyan Li, Xiaoxun Zhou, Guangbo Wu, Chaoan Guo, Jianyong Liu
The toxic effects of ammonia exposure on Litopenaeus vannamei have been widely reported, including tissue damage, oxidative stress, and metabolic disorders, but the ability of L. vannamei to recover from ammonia damage is still unclear. To further understand the adaptation mechanism of L. vannamei to ammonia, this study explored the effects of ammonia exposure and recovery on histopathology, physiological
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Developmental, behavioral, and biochemical effects of chronic exposure to sublethal concentrations of organic UV-filter compounds on a freshwater model species Aquat. Toxicol. (IF 4.1) Pub Date : 2024-10-28 Zoltán Németh, Réka Svigruha, András Ács, Anna Farkas, Kálmán Tapolczai, Károly Elekes, István Fodor, Zsolt Pirger
The prevalence of organic/chemical UV-filter compounds in aquatic ecosystems represents a growing environmental issue. The long-term toxicity risks of many UV-filters at environmentally relevant concentrations to aquatic biota are still less studied, especially in the case of invertebrates. This study was designed to evaluate the chronic toxicity of avobenzone (AVO), octocrylene (OCTO), and octinoxate
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Azoxystrobin induced genotoxicity in Pethia conchonius, a freshwater fish of river Teesta, India Aquat. Toxicol. (IF 4.1) Pub Date : 2024-10-28 Arpita Ray, Debojit Dutta, Bappaditya Ghosh, Min Bahadur
Azoxystrobin, a widely used fungicide, can contaminate water bodies through surface run-off, posing a risk to aquatic organisms. This study aimed to assess the genotoxic effects of azoxystrobin on the fish Pethia conchonius. The 96 h lethal concentration (LC50) of azoxystrobin was determined to be 0.514 mg/L. Based on LC50, three sub-lethal concentrations (SLCs) of 0.025 mg/L, 0.0514 mg/L, and 0.103
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Silver nanoparticles regulate antibiotic resistance genes by shifting bacterial community and generating anti-silver genes in estuarine biofilms Aquat. Toxicol. (IF 4.1) Pub Date : 2024-10-22 Xing-pan Guo, Xin-jie Chen, Nazupar Sidikjan, Rong-rong Sha
Biofilms are thought to be sinks for antibiotic resistance genes (ARGs) and nanoparticles (NPs), however, studies on the interactions between NPs and ARGs in biofilms are limited. This study focused on the occurrence and regulatory mechanisms of ARGs during the formation of biofilms with continuous treatment of zero-valent silver nanoparticles (Ag0-NPs) and Ag ions at an environmental concentration
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Ferroptosis involvement in the neurotoxicity of flunitrazepam in zebrafish Aquat. Toxicol. (IF 4.1) Pub Date : 2024-10-22 Yingjun Qin, Wenting Lin, Yuan Ren
In recent years, psychoactive drugs such as benzodiazepines (BZDs) have been frequently detected in water environments, however, there is still limited understanding regarding their potential impact on neurological health and underlying mechanisms. This study evaluated the neurotoxicity of the typical BZD drug flunitrazepam (FLZ, 0.2 and 5 μg/L) in zebrafish embryos and adults, and investigated the
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Microplastics colonized by Hafnia paralvei through biofilm formation regulated by c-di-GMP and cAMP promote its spread in water Aquat. Toxicol. (IF 4.1) Pub Date : 2024-10-20 Yi Li, Mengyuan Qin, Wenfang Niu, Chao Gao, Yuqi Wang, Shuo Han, Xiaohua Xia
Microplastics (MPs) colonized by pathogens pose significant risks to the environment and health of animals and humans, however, the strategies for pathogens colonization in MPs and the effects of its colonization on spread of pathogens have not been fully characterized. Here, we investigated the biofilm formation mechanism regulated by c-di-GMP in Hafnia paralvei Z11, and determined the effect of MPs
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Automated counting and classifying Daphnia magna using machine vision Aquat. Toxicol. (IF 4.1) Pub Date : 2024-10-19 Yang Ma, Wenping Xiao, Jinguo Wang, Xiang Kuang, Rongqin Mo, Yanfang He, Jianfeng Feng, Hengling Wei, Liwen Zheng, Yufei Li, Peixin Liu, Hao He, Yongbin He, Lemin Chen, Zhaojun Lin, Xiaoming Fan
Daphnia magna (D. magna) is a model organism widely used in aquatic ecotoxicology research due to its sensitivity to environmental changes. The survival and reproduction rates of D. magna are easily affected by toxic environments. However, their small size, fragility, and transparency, especially in neonate stages, make them challenging to count accurately. Traditionally, counting adult and neonate
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A transcriptomics-based analysis of mechanisms involved in the neurobehavioral effects of 6PPD-quinone on early life stages of zebrafish Aquat. Toxicol. (IF 4.1) Pub Date : 2024-10-19 Xuchun Qiu, Jie Tang, Yibing Zhang, Ming Li, Kun Chen, Yanhong Shi, Xiangyang Wu
As an emerging pollutant frequently detected in aquatic ecosystems, the toxicity of N-(1,3-dimethylbutyl)-N’-phenyl-p-phenylenediamine-quinone (6PPD-quinone) on fish has been confirmed, but insight into the mechanisms underlying those adverse effects is still limited. Thus, we exposed zebrafish embryos to 6PPD-quinone at 0, 0.25, 2.5, and 25 μg/L until 120 h post-fertilization (hpf), and investigated
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Thyroid endocrine disruption effects of OBS in adult zebrafish and offspring after parental exposure at early life stage Aquat. Toxicol. (IF 4.1) Pub Date : 2024-10-15 Xiaohui Zhao, Yaxuan Liu, Dan Yang, Shasha Dong, Jianhui Xu, Xiaohui Li, Xiaoying Li, Guanghui Ding
As an alternative to perfluorooctane sulfonate, sodium p-perfluorous nonenoxybenzene sulfonate (OBS) has been widely used and caused ubiquitous water pollution. However, its toxicity to aquatic organisms is still not well known. Therefore, in this study, parental zebrafish were exposed to OBS at environmentally relevant concentrations from ∼ 2 h post-fertilization to 21 days post-fertilization (dpf)
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Nanopolystyrene and phoxim pollution: A threat to hepatopancreas toxicity in Chinese mitten crab (Eriocheir sinensis) Aquat. Toxicol. (IF 4.1) Pub Date : 2024-10-15 Mengting Huang, Yuan Ma, Shunli Che, Longteng Shen, Zhicheng Wan, Shiping Su, Shuquan Ding, Xilei Li
Significant concerns have been raised by the widespread pollutants phoxim (PHO) and nanopolystyrene (NP) in the natural environment. This study evaluated the toxicity effects on the hepatopancreas of Eriocheir sinensis caused by NP and/or PHO at concentrations found in the environment. Subchronic exposure to NP and/or PHO triggered hepatopancreas histological damage within a 21-day exposure period
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Accumulation, biochemical responses and changes in the redox proteome promoted by Ag and Cd in the burrowing bivalve Scrobicularia plana Aquat. Toxicol. (IF 4.1) Pub Date : 2024-10-12 Ana María Herruzo-Ruiz, Chiara Trombini, Marta Sendra, Carmen Michán, Ignacio Moreno-Garrido, José Alhama, Julián Blasco
Silver (Ag) and cadmium (Cd) are non-essential metals that, as a result of natural processes and human activities, reach the aquatic environment where they interact with biota inducing potential toxic effects. To determine the biological effects of these metals on the endobenthic bivalve Scrobicularia plana, specimens were exposed to Ag and Cd at two concentrations, 5 and 50 μg∙L-1, for 7 days in a
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Fibrous microplastics in the environment: Sources, occurrence, impacts, and mitigation strategies Aquat. Toxicol. (IF 4.1) Pub Date : 2024-10-11 Shaochong Liu, Sizhi Liu, Xiangyang Xiao, Lu Liu, Willie Peijnenburg, Yan Xu, Yanhao Wang, Yaqi Yu, Lianzhen Li, Xilin She
Fibrous microplastics (FMPs), a unique class of microplastics, are increasingly recognized as a significant environmental threat due to their ubiquitous presence and potential risks to ecological and human health. This review provides a comprehensive overview of FMPs, including their sources, prevalence in various environmental media, and potential impacts. FMPs, which can be found in over 90 % of
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Detrimental effects of glyphosate on muscle metabolism in grass carp (Ctenopharyngodon idellus) Aquat. Toxicol. (IF 4.1) Pub Date : 2024-10-11 Biao Yan, Lijun Luo, Yindan Zhang, Jun Men, Yongyong Guo, Shengmin Wu, Jian Han, Bingsheng Zhou
Glyphosate, a commonly used herbicide, has been associated with environmental pollution and potential health risks to aquatic organisms. This study investigated the effects of glyphosate on the muscle metabolism of grass carp (Ctenopharyngodon idellus) following exposure to environmentally relevant concentrations. Over a 14-day exposure period to varying glyphosate levels, significant disruptions were
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Aryl phosphate ester-induced pericardial edema in zebrafish embryos is influenced by the ionic composition of exposure media Aquat. Toxicol. (IF 4.1) Pub Date : 2024-10-11 John Hoang, Jenna Wiegand, Zoe Mersman, Kevin Michalicek, Nicholas Jimenez, David C. Volz
Pericardial edema – fluid accumulation within the pericardium – is a frequently observed malformation in zebrafish embryo-based chemical toxicity screens. We recently discovered that the severity of triphenyl phosphate (TPHP)-induced pericardial edema was dependent on the ionic strength of exposure media. TPHP is an aryl phosphate ester (APE) widely used as a plasticizer and flame retardant. APEs are
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Persistent effects of larval exposure to glyphosate in mangrove rivulus fish Aquat. Toxicol. (IF 4.1) Pub Date : 2024-10-10 Lauren E. Corrigan, Jennifer K. Hellmann
Glyphosate, a key ingredient in many herbicides, is increasingly present in aquatic systems due to agricultural runoff. High doses of glyphosate cause defects in organisms due to its ability to interfere with physiological processes as an endocrine disruptor. We used the mangrove rivulus fish (Kryptolebias marmoratus) to evaluate the effects of larval exposure to glyphosate on non-target species in