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Permethrin exposure impacts zebrafish lipid metabolism via the KRAS-PPAR-GLUT signaling pathway, which is mediated by oxidative stress Aquat. Toxicol. (IF 4.1) Pub Date : 2024-07-08 Afrasyab Khan, Bibimaryam Khan, Shakeel Hussain, Yuhan Wang, Weijun Mai, Yongzhong Hou
Permethrin (Per) is a widely used and frequently detected pyrethroid pesticide in agricultural products and the environment. It may pose potential toxicity to non-target organisms. Per has been reported to affect lipid homeostasis, although the mechanism is undefined. This study aims to explore the characteristic transcriptomic profiles and clarify the underlying signaling pathways of Per-induced lipid
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Detection of microplastics in zebrafish housing systems: Can microplastic background contamination affect the final results of microplastic-related toxicological tests? Aquat. Toxicol. (IF 4.1) Pub Date : 2024-07-03 Bence Prikler, Gábor Bordós, Balázs Kriszt, Adrienn Micsinai, István Szabó, Brigitta Nyírő-Fekete, Zoltán Palotai, Edit Kaszab, Sándor Szoboszlay, Zsolt Csenki
Concentrations of microplastics (MPs) were determined in three commonly used zebrafish housing systems to see if their levels could affect the final results of laboratory microplastic-related toxicology tests.
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Pharmaceutical industrial wastewater exhibiting the co-occurrence of biofilm-forming genes in the multidrug-resistant bacterial community poses a novel environmental threat Aquat. Toxicol. (IF 4.1) Pub Date : 2024-07-02 Km Jyoti, Kuldeep Soni, Ram Chandra
The interaction of the environment with the effluent of wastewater treatment plants, having antibiotics, multidrug-resistant (MDR) bacteria, and biofilm-forming genes (BFGs), has vast environmental risks. Antibiotic pollution bottlenecks environmental bacteria and has the potential to significantly lower the biodiversity of environmental bacteria, causing an alteration in ecological equilibrium. It
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The impact of co-exposure to polystyrene microplastics and norethindrone on gill histology, antioxidant capacity, reproductive system, and gut microbiota in zebrafish (Danio rerio) Aquat. Toxicol. (IF 4.1) Pub Date : 2024-07-02 Shuhui Zhou, Hongjie Lin, Ziyun Liu, Xiaoyi Lian, Chang-Gui Pan, Zhongdian Dong, Zhong Lin, Chengyong Li, Liping Hou, Yan-Qiu Liang
In recent years, studies have focused on the combined ecological risks posed by microplastics and other organic pollutants. Although both microplastics and progestin residues are frequently detected in the aquatic environments, their ecological implications remain unknown. Adult zebrafish were exposed to polystyrene microplastics (PS, 200 nm, 200 μg/L), norethindrone (NET, 69.6 ng/L), and their mixture
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Effects of captan, mancozeb and azoxystrobin fungicides on motility, oxidative stress and fatty acid profiles in rainbow trout (Oncorhynchus mykiss) spermatozoa Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-30 Sami Gündüz, Burak Evren İnanan
An study using rainbow trout spermatozoa was designed to evaluate the toxic effects of different concentrations of captan (CPT), mancozeb (MCZ), and azoxystrobin (AZX) fungicides on motility parameters, lipid peroxidation, SOD activity, total antioxidant capacity (TAC), and DPPH inhibition. Moreover, changes in fatty acids profiles caused by the fungicides were determined for the first time. The results
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Chronic exposure to environmental concentrations of benzo[a]pyrene causes multifaceted toxic effects of developmental compromise, redox imbalance, and modulated transcriptional profiles in the early life stages of marine medaka (Oryzias melastigma) Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-29 Rabia Zeb, Xiaohan Yin, Fangyi Chen, Ke-Jian Wang
Polycyclic aromatic hydrocarbons (PAHs) accumulate and integrate into aquatic environments, raising concerns about the well-being and safety of aquatic ecosystems. Benzo[a]pyrene (BaP), a persistent PAH commonly detected in the environment, has been extensively studied. However, the broader multifaceted toxicity potential of BaP on the early life stages of marine fish during chronic exposure to environmentally
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Nitrite induces hepatic glucose and lipid metabolism disorders in zebrafish through mitochondrial dysfunction and ERs response Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-27 Hui Yang, Kang Ou-Yang, Ya He, Xinyu Wang, Liangmou Wang, Qing Yang, Dapeng Li, Li Li
Nitrite, a highly toxic environmental contaminant, induces various physiological toxicities in aquatic animals. Herein, we investigate the effects of nitrite exposure at concentrations of 0, 0.2, 2, and 20 mg/L on glucose and lipid metabolism in zebrafish. Our results showed that exposure to nitrite induced mitochondrial oxidative stress in zebrafish liver and ZFL cells, which were evidenced by increased
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Phenotypic adaptation of Chironomus riparius to chronic Bti exposure: effects on emergence time and nutrient content Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-27 Sara Kolbenschlag, Sebastian Pietz, Nina Röder, Klaus Schwenk, Mirco Bundschuh
Insects with aquatic larval and terrestrial adult life stages are a key component of coupled aquatic-terrestrial ecosystems. Thus, stressors applied to water bodies adversely affecting those larvae have the potential to influence the riparian zone through altered emergence, with differences in prey availability, timing, or nutrition. In this study, the common model organism , a species of Chironomidae
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The effects of ACE inhibitor Enalapril on Mytilus galloprovincialis: Insights into morphological and functional responses Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-27 Mariacristina Filice, Alessia Caferro, Daniela Amelio, Federica Impellitteri, Maria Assunta Iovine, Miriam Porretti, Caterina Faggio, Alfonsina Gattuso, Maria Carmela Cerra, Sandra Imbrogno
In the last decades, pharmaceuticals have emerged as a new class of environmental contaminants.
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Differential effects of antidepressant sertraline in glochidia-fish interactions involving drug transfer from parasite to host Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-22 Kateřina Gregarová, Shuran Zhao, Kateřina Grabicová, Pavel Horký, Roman Grabic, Ondřej Slavík, Tomáš Randák, Karel Douda
This study examined the impact of sertraline, an antidepressant common in treated wastewater, on the host-parasite dynamics between parasitic freshwater mussel (, Unionidae) larvae (glochidia) and their host fish (, Cyprinidae). Employing a full-factorial design, both fish and glochidia were subjected to sertraline at the combinations of 0 µg (control), 0.2 µg (environmentally relevant concentration)
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Silybin protected from avermectin-induced carp (Cyprinus carpio) nephrotoxicity by regulating PPAR-γ-involved inflammation, oxidative stress, ferroptosis and autophagy Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-21 Jiajie Gan, Xiaomeng Ji, Xiaohui Jin, Mengyuan Zhou, Chenbeibei Yang, Ziyun Chen, Chaoyang Yin, Zibo Dong
Avermectin, a widely used deworming drug, poses a significant threat to fisheries. Silybin is recognized for its antioxidant and anti-inflammatory properties. The kidney, being crucial for fish survival, plays a vital role in maintaining ion balance, nitrogen metabolism, and hormone regulation. While residual avermectin in water could pose a risk to carp (Cyprinus carpio), it remains unclear whether
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Tire and road wear particles in the aquatic organisms – A review of source, properties, exposure routes, and biological effects Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-21 Tianyu Zhao, Yun Zhang, Qianqian Song, Qingxuan Meng, Siyu Zhou, Jing Cong
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Environmentally relevant estrogens impaired spermatogenesis and sexual behaviors in male and female zebrafish Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-21 Mei-Ling Tan, Yan-Jun Shen, Qi-Liang Chen, Feng-Rui Wu, Zhi-Hao Liu
Environmental estrogens (EEs) are found extensively in natural waters and negatively affect fish reproduction. Research on the reproductive toxicity of EEs mixtures in fish at environmentally relevant concentrations is scarce. In this study, adult male zebrafish were exposed for 60 days to EES (a mixture of EEs), EE2-low (5.55 ng/L, with an estrogenic potency equal to EES), and EE2-high (11.1 ng/L)
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Phenytoin causes behavioral abnormalities and suppresses kisspeptin expression, reducing reproductive performance in Japanese medaka Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-21 Kensuke Mitsunaga, Sheikh Shohag, Chew Jia Ming, Chee Kong Yap, Yoshifumi Horie
Phenytoin, an antiepileptic drug, induces neurotoxicity and abnormal embryonic development and reduces spontaneous locomotor activity in fish. However, its effects on other endpoints remain unclear. Therefore, we investigated the effects of phenytoin on the swimming behavior and reproductive ability of Japanese medaka. Abnormalities in swimming behavior, such as imbalance, rotation, rollover, and vertical
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Effects of polystyrene microspheres on the swimming behavior and metabolism of grass carp (Ctenopharyngodon idella) Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-20 Malik Haris Ali, Ying-ping Huang, David Johnson, Zhi-ying Tu, Xi Yuan
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The effects of nanoplastics and microcystin-LR coexposure on Aristichthys nobilis at the early developmental stages Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-19 Chaonan Zhang, Fei Wang, Feifan Bao, Junjie Zhu, Jiang Xu, Daohui Lin
Nanoplastics (NPs) and microcystin-LR (MC-LR) are two common and harmful pollutants in water environments, especially at aquafarm where are full of plastic products and algae. It is of great significance to study the toxic effects and mechanisms of the NPs and/or MC-LR on fish at the early stage. In this study, the embryo and larvae of a filtering-feeding fish, , were used as the research objects.
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Exploring the endocrine disrupting potential of a complex mixture of PAHs in the estrogen pathway in Oreochromis niloticus hepatocytes Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-15 Tugstênio Lima de Souza, Jessica Zablocki da Luz, Aliciane de Almeida Roque, Iracema Opuskevitch, Fernando Cesar Alves da Silva Ferreira, Ciro Alberto de Oliveira Ribeiro, Francisco Filipak Neto
This study aimed to investigate the toxicity and endocrine disrupting potential of a complex mixture of polycyclic aromatic hydrocarbons (PAHs) in the estrogen pathway using hepatocytes of Nile tilapia , the hepatocytes were exposed to various concentrations of the PAH mixture, and multiple endpoints were evaluated to assess their effects on cell viability, gene expression, oxidative stress markers
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Naphthalene and phenanthrene affect differentially two glutathione S-transferases (GSTs) expression, GST activity, and glutathione content in white shrimp P. vannamei Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-15 Laura Camacho-Jiménez, Lilia Leyva-Carrillo, Silvia Gómez-Jiménez, Gloria Yepiz-Plascencia
Polycyclic aromatic hydrocarbons (PAHs) are persistent organic pollutants ubiquitous in coastal ecosystems. The white shrimp naturally inhabits in coastal areas and is cultivated in farms located nearby the oceans. PAHs can damage shrimp health, endanger natural populations, and lower shrimp aquaculture productivity. However, crustaceans have enzymes capable of metabolizing organic xenobiotics as PAHs
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Long-term exposure of metamifop affects sex differentiation and reproductive system of zebrafish (Danio rerio) Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-15 Mengyu Guo, Feng Zhao, Mengna Zhang, Xiangguang Chen, Manman Duan, Yao Xie, Zhongyu Zhang, Jiazhen Jiang, Lihong Qiu
The extensive use of herbicide metamifop (MET) in rice fields for weeds control will inevitably lead to its entering into water environments and threaten the aquatic organisms. Previous researches have demonstrated that sublethal exposure of MET significantly affected zebrafish development. Yet the long-term toxicological impacts of MET on aquatic life remains unknown. Herein, we investigated the potential
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Harmful effects of microplastics on respiratory system of aquatic animals: A systematic review and meta-analysis Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-13 Qiurong Zhang, Xin Zhou, Yu Sun, Qingfang Deng, Qing Wu, Zhirui Wen, Huaguo Chen
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Co-exposure to microplastic and plastic additives causes development impairment in zebrafish embryos Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-13 Go-Eun Kim, Dae-Wook Kim, Seonggeun Zee, Kanghee Kim, June-Woo Park, Chang-Beom Park
Since the run off of microplastic and plastic additives into the aquatic environment through the disposal of plastic products, we investigated the adverse effects of co-exposure to microplastics and plastic additives on zebrafish embryonic development. To elucidate the combined effects between microplastic mixtures composed of microplastics and plastic additives in zebrafish embryonic development,
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Toxicological effects of nodularin on the reproductive endocrine system of female zebrafish (Danio rerio) Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-10 Chayan Biswas, Madhuchhanda Adhikari, Kousik Pramanick
Nodularin is a potent cyanotoxin that has been detected in aquatic environments as well as in the body of aquatic organisms throughout the world, but its effects on the reproductive system are yet to be explored. The present study investigated the toxic effects of environmentally relevant concentrations of nodularin on the reproductive endocrine system of female zebrafish (). After exposure to nodularin
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Insights into the combined toxicity and mechanisms of BDE-47 and PFOA in marine blue mussel: An integrated study at the physiochemical and molecular levels Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-10 Qianqian Geng, Liang Zou, Mengmeng Guo, Jixing Peng, Fengling Li, Yujie Bi, Shuqi Jiang, Hanlin Qin, Zhijun Tan
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Environmentally relevant concentrations of naphthenic acids initiate intestinal injury and gut microbiota dysbiosis in marine medaka (Oryzias melastigma) Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-07 Huanxin Zhang, Lihua Cui, Panpan Si, Yumiao Zhou, Yu Zhang, Youru Zhang, Qiang Kong
Naphthenic acids (NAs) are important pollutants in marine crude oils and have obvious toxic effects on marine organisms. However, the effects of NAs on the intestine are largely unknown. Thus, we evaluated the effects of NAs exposure in the intestines of marine medaka. Fish were experimentally exposed to NAs (0.5 mg/L, 5 mg/L, and 10 mg/L) for 96 h and monitored for changes in intestinal histology
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Feeding on stressed algae exerts important effects on life history traits of Daphnia magna in a multi-stressor environment Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-06 Sabiha Akter, Katharina Wilfert, Olayemi Razaq Saliu, Jonas Schoelynck, Gudrun De Boeck
Freshwater ecosystems are increasingly exposed to anthropogenic eutrophication, including high nitrogen. In addition, climate change is leading to more intense and frequent heatwaves, which have enormous impacts on all trophic levels of the ecosystem. Any change in the lower trophic levels, e.g., the phytoplankton, also introduces stress to higher trophic levels e.g., the zooplankton crustacean Daphnia
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Bioaccumulation and sub-lethal physiological effects of metal mixtures on mussel, Mytilus edulis: Continuous exposure to a binary mixture of mercury and cadmium Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-06 Dokuboba Amachree, Alan John Moody, Richard D. Handy
In the natural ecosystem, aquatic organisms are exposed to a cocktail of chemicals that may result in toxicological responses differing from those of individual chemicals. In the present study, mussels were exposed using a semi-static and triplicated design to either control (no added metal), 50 µg l (Hg alone), 50 µg l (Cd alone), or 50 µg l Hg plus 50 µg l Cd (Hg + Cd) mixture for 14 days. Tissues
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Interactions of binary mixtures of metals on rainbow trout (Oncorhynchus mykiss) heart mitochondrial H2O2 homeodynamics Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-02 Pius Abraham Tetteh, Zahra Kalvani, Don Stevens, Ravinder Sappal, Collins Kamunde
For continuous pumping of blood, the heart needs a constant supply of energy (ATP) that is primarily met via oxidative phosphorylation in the mitochondria of cardiomyocytes. However, sustained high rates of electron transport for energy conversion redox reactions predisposes the heart to the production of reactive oxygen species (ROS) and oxidative stress. Mitochondrial ROS are fundamental drivers
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Safer and greener chemicals for the aquatic ecosystem: Chemometric modeling of the prolonged and chronic aquatic toxicity of chemicals on Oryzias latipes Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-01 Ankur Kumar, Probir Kumar Ojha, Kunal Roy
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Lethal and behavioral effects of semi-purified microcystins, Micropeptin and apolar compounds from cyanobacteria on freshwater microcrustacean Thamnocephalus platyurus Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-01 Mariana de Almeida Torres, Anne Dax, Ingrid Grand, Colette vom Berg, Ernani Pinto, Elisabeth M.-L Janssen
The mass proliferation of cyanobacteria, episodes known as blooms, is a concern worldwide. One of the most critical aspects during these blooms is the production of toxic secondary metabolites that are not limited to the four cyanotoxins recognized by the World Health Organization. These metabolites comprise a wide range of structurally diverse compounds that possess bioactive functions. Potential
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Impacts of caffeine on fathead minnow behaviour and physiology Aquat. Toxicol. (IF 4.1) Pub Date : 2024-06-01 Jacqueline Bikker, Helen MacDougall-Shackleton, Leslie M. Bragg, Mark R. Servos, Bob B.M. Wong, Sigal Balshine
Pollution from regularly used substances such as pharmaceuticals, cleaning agents, and even food and beverages is an increasing problem in the environment. Caffeine, a commonly ingested stimulant, is one such contaminant that has been detected in aquatic environments worldwide. Yet, little is known about how ecologically relevant concentrations of caffeine influence the morphology, behaviour, and physiology
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Energy strategy alteration, rather than toxicity itself, interferes with the population fluctuation of Brachionus plicatilis exposed to water-accommodated fractions (WAFs) of crude oil Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-31 Yuanyuan Li, Yaya Zhang, Hui Zhang, Mengxue Xu, Qiyue Cao, You Wang
Oil spills are reported to have conflicting impacts of either injury or resilience on zooplankton communities, and physiological plasticity is speculated to be the possible causative factor. But how? An explanation was sought by exposing the marine rotifer to a series of water-accommodated fractions (WAFs) of crude oil under controlled laboratory conditions, and population dynamics, which is the core
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Immunomodulatory effects of single and combined exposure to ZnO and TiO2 nanoparticles on rainbow trout challenged with Aeromonas salmonicida achromogenes Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-31 Mahaut Beghin, Jérôme Lambert, Joachim Sturve, Valérie Cornet, Patrick Kestemont
The increasing release of engineered nanoparticles (ENPs) in aquatic ecosystems stresses the need for stringent investigations of nanoparticle mixture toxicity towards aquatic organisms. Here, the individual and combined immunotoxicity of two of the most consumed ENPs, the ZnO and the TiO ones, was investigated on rainbow trout juveniles (). Fish were exposed to environmentally realistic concentrations
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Oxidative damage to mitochondrial DNA in maternal zebrafish (Danio rerio) exposed to dibutyl phthalate at environmentally relevant level Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-31 Tingting Hou, Zhen Yang, Lei Wang, Huiqiang Zhang, Wenpeng Ma, Dingfu Zhang, Xiaoteng Fan
Dibutyl phthalate (DBP) is a widely-used plasticizer that is dispersed in various environments, causing significant pollution and health risks. The toxic mechanism of DBP has been discussed in recent years, while the susceptibility of mitochondrial DNA (mtDNA) to DBP exposure and the resulting damage remain unclear. In this study, maternal zebrafish were exposed to environmentally relevant concentration
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Isolated and mixed effects of pure and formulated abamectin and difenoconazole on biochemical biomarkers of the gills of Danio rerio Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-29 Ana Letícia Madeira Sanches, Thandy Junio da Silva Pinto, Michiel Adriaan Daam, Fabrício Barreto Teresa, Bruna Horvath Vieira, Marina Vanderlei Reghini, Eduardo Alves de Almeida, Evaldo Luiz Gaeta Espíndola
Pesticides are released into the environment daily, and their effects on nontarget species in aquatic ecosystems have been widely reported. To evaluate the adverse effects caused in adults of species exposed to the pesticides abamectin, difenoconazole, and their commercial formulations (Kraft 36EC® and Score 250EC®), both isolated and in mixtures, biochemical biomarkers were analyzed in the gills of
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Toxicity comparison and risk assessment of two chlorinated organophosphate flame retardants (TCEP and TCPP) on Polypedates megacephalus tadpoles Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-29 Yi-Ge Xie, Zi-Ying Wang, Wen-Qi Xie, Zi-Yong Xiang, Xin-Dan Cao, Jia-Jun Hao, Guo-Hua Ding
Tris(2-chloroethyl) phosphate (TCEP) and tris(1‑chloro-2-propyl) phosphate (TCPP) are widely used as chlorinated organophosphate flame retardants (OPFRs) due to their fire-resistance capabilities. However, their extensive use has led to their permeation and pollution in aquatic environments. Using amphibians, which are non-model organisms, to test the toxic effects of OPFRs is relatively uncommon.
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UV filter benzophenone-2: Effects on zebrafish (Danio rerio) cytochrome P450 Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-27 Ileska M. Casiano-Muñiz, Melissa I. Ortiz-Román, José A. Carmona-Negrón, Félix R. Román-Velázquez
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Evaluation of thyroid-disrupting effects of bisphenol F and bisphenol S on zebrafish (Danio rerio) using anti-transthyretin monoclonal antibody-based immunoassays Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-27 Yuqi Zheng, Yuejiao Li, Samreen, Zhenzhong Zhang, Minhao Liu, Xumeng Cui, Jun Wang
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Advances of microplastics ingestion on the morphological and behavioral conditions of model zebrafish: A review Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-27 Suraiya Alam Rojoni, Md. Tanvir Ahmed, Mostafizur Rahman, Md. Mer Mosharraf Hossain, Md Sadek Ali, Monjurul Haq
Concerns have been conveyed regarding the availability and hazards of microplastics (MPs) in aquatic biota due to their widespread presence in aquatic habitats. Zebrafish () are widely used as a model organism to study the adverse impacts of MPs due to their several compelling advantages, such as their small size, ease of breeding, inexpensive maintenance, short life cycle, year-round spawning, high
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Effects of food quantity on the ingestion and egestion of MPs with different colors by Daphnia magna Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-27 Danhua Lan, Hua He, Xueyi Song, Yini Ma
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Comparative effects of polyvinyl chloride microplastics on the brittle star Ophiactis virens and the amphibian Xenopus laevis Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-27 Renato Bacchetta, Arianna Pica, Nadia Santo, Paolo Tremolada, Michela Sugni
In this study, we investigated the effects of PVC microplastics (PVC-MPs) using two different animal models: the brittle star and the African clawed frog . This is the first study using an environmental relevant sample of PVC-MPs obtained through mechanical fragmentation of a common PVC plumbing pipe. Exposure experiments on brittle star were performed on the adult stage for a duration of 14 days,
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Dietary lipid supplementation alleviated the impacts of polystyrene nanoplastic exposure in Litopenaeus vannamei Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-26 Yiming Li, Yucong Ye, Haojuan Yuan, Siwen Li, Na Rihan, Xingguo Liu, Yunlong Zhao, Xuan Che
The widespread occurrence of nanoplastic (NP) pollution in the environment is a growing concern, and its presence poses a potential threat to cultured aquatic animals. Previously, we found that NPs can significantly affect the lipid metabolism of shrimp. However, relevant reports about the effects of increasing dietary lipid levels on NP toxicity are lacking. Therefore, we explored the effects of dietary
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Experimental testing of two urban stressors on freshwater biofilms Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-24 Romain Vrba, Isabelle Lavoie, Nicolas Creusot, Mélissa Eon, Débora Millan-Navarro, Agnès Feurtet-Mazel, Nicolas Mazzella, Aurélie Moreira, Dolors Planas, Soizic Morin
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Acetylcholinesterase and dopamine inhibition suppress the filtration rate, burrowing behaviours, and immunological responses induced by bisphenol A in the hemocytes and gills of date mussels, Lithophaga lithophaga Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-23 Heba-Tallah Abd Elrahim Abd Elkader, Ahmed S. Al-Shami
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Long-term disinfectant exposure on intestinal immunity and microbiome variation of grass carp Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-23 Fei Shi, Lixin Ma, Zhilong Chen, Yao Huang, Li Lin, Zhendong Qin
The gut microbiome is crucial in maintaining fish health homeostasis. Disinfectants can kill important pathogens and disinfect fish eggs, yet their effect on the immune pathways and intestinal microbiome in healthy fish remains unknown. In this study, we investigated the effects of two disinfectants on the transcriptome profiles, immunological response, and gut microbiota dynamics of grass carp over
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Ultrastructural changes, pigment responses and bioaccumulation in the microalga Phaeodactylum tricornutum Bohlin exposed to BPA analogues Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-21 Jacopo Fabrello, Sofia Guidorizzi, Maria Ciscato, Mariano Battistuzzi, Emanuela Moschin, Francesca Dalla Vecchia, Isabella Moro, Marco Roverso, Sara Bogialli, Valerio Matozzo
As well-known, microalgae have a pivotal role in aquatic environments, being the primary producer. In this study, we investigated the effects of Bisphenol A (BPA) analogues on cell ultrastructure, reactive oxygen species (ROS) production and photosynthetic pigment responses in the diatom . Microalgae were exposed during both exponential and stationary growth phases to an environmental relevant concentration
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The generation gap in endocrine disruption: Can the integrated fish endocrine disruptor test (iFEDT) bridge the gap by assessing intergenerational effects of thyroid hormone system disruption? Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-21 Teresa Fagundes, Pauline Pannetier, Lisa Gölz, Laura Behnstedt, Jane Morthorst, Lucia Vergauwen, Dries Knapen, Henrik Holbech, Thomas Braunbeck, Lisa Baumann
Thyroid hormones (THs) act early in ontogenesis, even prior to the differentiation of thyrocytes. Maternal transfer of THs is therefore known to play an essential role in early development. Current OECD test guidelines for the assessment of TH system disruption (THSD) do not address inter- or transgenerational effects. The integrated fish endocrine disruptor test (iFEDT), a test combining parental
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Effect of ultraviolet aged polytetrafluoroethylene microplastics on copper bioavailability and Microcystis aeruginosa growth Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-21 Juanjuan Zhang, Zihan Lin, Fuxun Ai, Wenchao Du, Ying Yin, Hongyan Guo
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Multi-level toxicity assessment of polylactic acid (PLA) microplastics on the cladoceran Daphnia magna Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-21 Beatrice De Felice, Stefano Gazzotti, Marco Aldo Ortenzi, Marco Parolini
The accumulation of plastics waste in the environment has raised a worrisome concern, moving the society to seek out for sustainable solutions, such as the transition from the use of fossil-based, conventional plastics to bioplastics (BPs). However, once in the environment bioplastics have the same probability to accumulate and experience weathering processes than conventional plastics, leading to
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Bioconcentration, oxidative stress and molecular mechanism of the toxic effect of acetamiprid exposure on Xenopus laevis tadpoles Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-20 Hong Chen, Ya Yang, Lina Ai, Lanying Li, Renyue Ming, Ping Lu
Acetamiprid is a neonicotinoid commonly detected in aquatic ecosystems, with residual concentrations of up to 0.41 mg/L in surface water, posing a threat to the health of nontarget aquatic organisms. However, studies on the potential toxicity and underlying mechanisms of action of acetamiprid on nontarget aquatic organisms are limited. This study investigated the acute and short-term toxicity of acetamiprid
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Activation of stress reactions in the dinophyte microalga Prorocentrum cordatum as a consequence of the toxic effect of ZnO nanoparticles and zinc sulfate Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-20 Natalia Shoman, Ekaterina Solomonova, Arkady Akimov, Olga Rylkova, Irina Mansurova
According to the results of the experimental study, the main regularities of changes in morphological, structural-functional and fluorescent indices of were established when zinc oxide nanoparticles ZnO NPs (0.3–6.4 mg L) and Zn in form of salt (0.09–0.4 mg L) were added to the medium. The studied pollutants have cytotoxic (growth inhibition, development of oxidative stress, destruction of cytoplasmic
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Molecular variations to the proteome of zebrafish larvae induced by environmentally relevant copper concentrations Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-17 Sarah L. Green, Ewen Silvester, Sebastian Dworkin, Manisha Shakya, Annaleise Klein, Rohan Lowe, Keshava Datta, Aleicia Holland
Contaminants are increasingly accumulating in aquatic environments and biota, with potential adverse effects on individual organisms, communities and ecosystems. However, studies that explore the molecular changes in fish caused by environmentally relevant concentrations of metals, such as copper (Cu), are limited. This study uses embryos of the model organism zebrafish () to investigate effect of
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Potential threats of microplastics and pathogenic bacteria to the immune system of the mussels Mytilus galloprovincialis Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-17 Chaofan Sun, Jia Teng, Dongyu Wang, Jiashen Li, Xiaodan Wang, Jianmin Zhao, Encui Shan, Hao Chen, Qing Wang
As one of the main components of marine pollution, microplastics (MPs) inevitably enter the mussel aquaculture environment. At the same time, pathogenic bacteria, especially pathogens such as , can cause illness outbreaks, leading to large-scale death of mussels. The potential harm of MPs and pathogenic bacteria to bivalve remains unclear. This study designed two experiments (1) mussels () were exposed
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Bisphenol S exposed changes in intestinal microflora and metabolomics of freshwater crayfish, Procambarus clarkii Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-17 Changchang Pu, Yuanyi Liu, Jianshuang Ma, Lixiao Hou, Yinfeng Cheng, Boyang Zhang, Bingke Wang, Aimin Wang, Chunnuan Zhang
Bisphenol S (BPS), a typical endocrine-disrupting chemical (EDC), can cause hepatopancreas damage and intestinal flora disturbance. Comprehensive studies on the mechanisms of acute toxicity in crustaceans are lacking. In this study, 16S rRNA and liquid chromatography were used to investigate intestinal microbiota and metabolites of freshwater crayfish (). In this study, freshwater crayfish were exposed
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Developmental toxicity and mechanism of dibutyl phthalate and alternative diisobutyl phthalate in the early life stages of zebrafish (Danio rerio) Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-16 Huan-Yu Tao, Jianghong Shi, Jiawei Zhang, Hui Ge, Mengtao Zhang, Xiao-Yan Li
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Ultrastructural investigation of iron oxide nanoparticles accumulation in the liver of common carp (Cyprinus carpio Linnaeus, 1758) Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-16 Aysel Hajiyeva, Chingiz Mamedov, Eldar Gasimov, Fuad Rzayev, Orkhan Isayev, Rovshan Khalilov, Aziz Eftekhari, Khaled Zoroufchi Benis
In recent years, the intensive production of nanoparticles with a wide application has led to their transfer to the environment, including the water ecosystem. The accumulation of nanoparticles in fish, causing various pathological changes in the host, raises certain concerns. In the current study, we investigated the penetration and bioaccumulation of FeO nanoparticles, in the liver of common carp
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Impacts of microplastic and seawater acidification on unicellular red algae: Growth response, photosynthesis, antioxidant enzymes, and extracellular polymer substances Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-15 Jianke Huang, Hanlong Wang, Xiwen Xue, Ruizeng Zhang
Microplastics (MPs) pollution and seawater acidification have increasingly become huge threats to the ocean ecosystem. Their impacts on microalgae are of great importance, since microalgae are the main primary producers and play a critical role in marine ecosystems. However, the impact of microplastics and acidification on unicellular red algae, which have a unique phycobiliprotein antenna system,
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The mechanism of reactive oxygen species generation, DNA damage and apoptosis in hemocytes of Litopenaeus vannamei under ammonia nitrogen exposure Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-15 Ruixue Tong, Yaobing Li, Xin Yu, Ning Zhang, Qilong Liao, Luqing Pan
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Growth increase and gonadal dysfunction of the lined seahorse triggered by zinc exposure Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-13 Xue Han, Chunyan Li, Geng Qin, Xin Wang, Bo Zhang, Qiang Lin
Seahorses are characterized by unique characteristics such as a male pregnancy reproductive strategy and grasping preferences, which make these species vulnerable to various environmental risks. Zinc (Zn) is one of the most frequently occurring toxic elements in coastal waters; however, little is known about the effect of Zn exposure on seahorses. In the present study, line seahorses () were exposed
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Atlantic salmon gill epithelial cell line ASG-10, an in vitro model for studying effects of microplastics in gills Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-10 Anita Solhaug, Sarah Vlegels, Gunnar Sundstøl Eriksen
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Naïve and induced tolerance of 15 amphibian populations to three commonly applied insecticides Aquat. Toxicol. (IF 4.1) Pub Date : 2024-05-10 Devin K. Jones, Devin G. DiGiacopo, Brian M. Mattes, Erika Yates, Jessica Hua, Jason T. Hoverman, Rick A. Relyea
Human impacts on ecological communities are pervasive and species must either move or adapt to changing environmental conditions. For environments polluted by contaminants, researchers have found hundreds of target pest species evolving increased tolerance, but we have substantially fewer cases of evolved tolerance in non-target species. When species do evolve increased tolerance, inducible tolerance