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Long-term exposure to sediment-associated antidepressants impacts life-history traits in an estuarine deposit-feeding worm
Aquatic Toxicology ( IF 4.1 ) Pub Date : 2024-12-01 , DOI: 10.1016/j.aquatox.2024.107189 Martina Santobuono, Wing Sze Chan, Elettra D´Amico, Henriette Selck
Aquatic Toxicology ( IF 4.1 ) Pub Date : 2024-12-01 , DOI: 10.1016/j.aquatox.2024.107189 Martina Santobuono, Wing Sze Chan, Elettra D´Amico, Henriette Selck
Hydrophobic pollutants, such as the antidepressant sertraline (SER), tend to sorb to particles in the water column and subsequently accumulate in the sediment. Long-term exposure to these pollutants may significantly affect sediment-dwelling organisms´ fitness and behavior. To address this knowledge gap, we investigated the impact of chronic exposure to a range of environmentally relevant and higher concentrations of sediment-associated SER on the deposit-feeding polychaete Capitella teleta . Since certain antidepressants can function as neurotoxic chemicals and endocrine disruptors on non-target species, we examined feeding rate and burrowing behavior in adult worms after 23 days of exposure (Experiment 1), and key life-history traits in juvenile worms during 35 days of exposure (Experiment 2) to sediment-associated SER (0.33 - 100 µg/g dw sediment). SER did not affect survival but reduced maturation and time to first reproduction: 37%, 50%, and 29% of the worms exposed respectively to SER 0.33, 3.3 and 33 µg/g reached maturation on day 21, whereas worms in the other treatments did not mature (0%; control) or reached a lower maturation degree (6%; 100 µg/g). Although not statistically significant, growth, feeding, and burrowing manifested non-monotonic trends: at environmentally relevant SER concentrations adults increased feeding and extended time to fully burrow into the sediment, and juveniles increased growth, whereas high concentrations had an inhibitory or no effect. Reproductive endpoints appeared most sensitive to chronic SER exposure. Even at low environmental concentrations, antidepressants can cause sublethal effects in non-target species, potentially affecting population dynamics and ecosystem functioning. Further research is key to fully understanding the ecological impact of hydrophobic chemicals in natural environments.
中文翻译:
长期暴露于沉积物相关抗抑郁药会影响河口沉积食性蠕虫的生活史特征
疏水性污染物,例如抗抑郁药舍曲林 (SER),往往会吸附到水柱中的颗粒上,随后积聚在沉积物中。长期接触这些污染物可能会显着影响沉积物生物的健康和行为。为了解决这一知识差距,我们调查了长期暴露于一系列与环境相关和更高浓度的沉积物相关 SER 对沉积摄食多毛类 Capitella teleta 的影响。由于某些抗抑郁药可以在非目标物种上起神经毒性化学物质和内分泌干扰物的作用,我们检查了成虫暴露 23 天后的摄食速率和穴居行为(实验 1),以及幼虫在暴露 35 天期间的关键生活史特征(实验 2)与沉积物相关的 SER(0.33 - 100 μg/g dw 沉积物)。SER 不影响存活,但缩短了成熟和首次繁殖的时间:分别暴露于 SER 0.33、3.3 和 33 μg/g 的蠕虫中有 37%、50% 和 29% 在第 21 天达到成熟,而其他处理中的蠕虫未成熟(0%;对照)或达到较低的成熟度(6%;100 μg/g)。虽然没有统计学意义,但生长、摄食和挖洞表现出非单调趋势:在与环境相关的 SER 浓度下,成虫增加采食并延长完全钻入沉积物的时间,幼虫增加生长,而高浓度有抑制性或没有影响。生殖终点似乎对慢性 SER 暴露最敏感。即使在低环境浓度下,抗抑郁药也能对非目标物种造成亚致死作用,从而可能影响种群动态和生态系统功能。 进一步的研究是充分了解自然环境中疏水性化学品对生态影响的关键。
更新日期:2024-12-01
中文翻译:
长期暴露于沉积物相关抗抑郁药会影响河口沉积食性蠕虫的生活史特征
疏水性污染物,例如抗抑郁药舍曲林 (SER),往往会吸附到水柱中的颗粒上,随后积聚在沉积物中。长期接触这些污染物可能会显着影响沉积物生物的健康和行为。为了解决这一知识差距,我们调查了长期暴露于一系列与环境相关和更高浓度的沉积物相关 SER 对沉积摄食多毛类 Capitella teleta 的影响。由于某些抗抑郁药可以在非目标物种上起神经毒性化学物质和内分泌干扰物的作用,我们检查了成虫暴露 23 天后的摄食速率和穴居行为(实验 1),以及幼虫在暴露 35 天期间的关键生活史特征(实验 2)与沉积物相关的 SER(0.33 - 100 μg/g dw 沉积物)。SER 不影响存活,但缩短了成熟和首次繁殖的时间:分别暴露于 SER 0.33、3.3 和 33 μg/g 的蠕虫中有 37%、50% 和 29% 在第 21 天达到成熟,而其他处理中的蠕虫未成熟(0%;对照)或达到较低的成熟度(6%;100 μg/g)。虽然没有统计学意义,但生长、摄食和挖洞表现出非单调趋势:在与环境相关的 SER 浓度下,成虫增加采食并延长完全钻入沉积物的时间,幼虫增加生长,而高浓度有抑制性或没有影响。生殖终点似乎对慢性 SER 暴露最敏感。即使在低环境浓度下,抗抑郁药也能对非目标物种造成亚致死作用,从而可能影响种群动态和生态系统功能。 进一步的研究是充分了解自然环境中疏水性化学品对生态影响的关键。