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miR-3606-3p alleviates skin fibrosis by integratively suppressing the integrin/FAK, p-AKT/p-ERK, and TGF-β signaling cascades J. Adv. Res. (IF 11.4) Pub Date : 2024-11-20 Yahui Chen, Yiyi Gong, Mengkun Shi, Haoxing Zhu, Yulong Tang, Delin Huang, Wei Wang, Chenyi Shi, Xueyi Xia, Ying Zhang, Jianlan Liu, Jia Huang, Mengguo Liu, Huyan Chen, Yanyun Ma, Ziyu Wang, Lei Wang, Wenzhen Tu, Yinhuan Zhao, Jinran Lin, Xiangguang Shi
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Interleukin-10 deficiency suppresses colorectal cancer metastasis by enriching gut Parabacteroides distasonis J. Adv. Res. (IF 11.4) Pub Date : 2024-11-19 Jing Yu, Lili Feng, Zhanhao Luo, Jingyi Yang, Qiang Zhang, Chen Liu, Dayi Liang, Yanchun Xie, Hongmin Li, Junli Gong, Zhen He, Ping Lan
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An accurate prediction for respiratory diseases using deep learning on bronchoscopy diagnosis images J. Adv. Res. (IF 11.4) Pub Date : 2024-11-19 Weiling Sun, Pengfei Yan, Minglei Li, Xiang Li, Yuchen Jiang, Hao Luo, Yanbin Zhao
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Bacteroides uniformis ameliorates pro-inflammatory diet-exacerbated colitis by targeting endoplasmic reticulum stress-mediated ferroptosis J. Adv. Res. (IF 11.4) Pub Date : 2024-11-19 Caiguang Liu, Linxin Liu, Zhenyi Tian, Shukai Zhan, Yun Qiu, Manying Li, Tong Li, Ren Mao, Shenghong Zhang, Minhu Chen, Zhirong Zeng, Xiaojun Zhuang
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Self-adhesion conductive cardiac patch based on methoxytriethylene glycol-functionalized graphene effectively improves cardiac function after myocardial infarction J. Adv. Res. (IF 11.4) Pub Date : 2024-11-19 Xu Wang, Hao Wang, Xin Liu, Yuan Zhang, Jiamin Li, Heng Liu, Jing Feng, Wenqian Jiang, Ling Liu, Yongchao Chen, Xiaohan Li, Limin Zhao, Jing Guan, Yong Zhang
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Transient receptor potential channels in viral infectious diseases: Biological characteristics and regulatory mechanisms J. Adv. Res. (IF 11.4) Pub Date : 2024-11-17 Wen-Hui Qi, Na Tang, Zhi-Jing Zhao, Xiao-Qiang Li
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Kaempferol regulating macrophage foaming and atherosclerosis through piezo1-mediated MAPK/NF-κB and Nrf2/HO-1 signaling pathway J. Adv. Res. (IF 11.4) Pub Date : 2024-11-17 Tianjiao Chu, Yuman Wang, Shihao Wang, Jinze Li, Zheng Li, Zihao Wei, Jing Li, Yifei Bian
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Generalized Deep Learning for Histopathology Image Classification Using Supervised Contrastive Learning J. Adv. Res. (IF 11.4) Pub Date : 2024-11-16 Md Mamunur Rahaman, Ewan K.A. Millar, Erik Meijering
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An efficient discrete Chebyshev polynomials strategy for tempered time fractional nonlinear Schrödinger problems J. Adv. Res. (IF 11.4) Pub Date : 2024-11-16 Mohammad Hossein Heydari, Dumitru Baleanu
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Attention Over Vulnerable Brain Regions Associating Cerebral Palsy Disorder and Biological Markers J. Adv. Res. (IF 11.4) Pub Date : 2024-11-16 Muhammad Hassan, Jieqong Lin, Ahmed Ameen Fateh, Wei Pang, Luning Zhang, Wang Di, Guojun Yun, Hongwu Zeng
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Glycyrrhiza, a commonly used medicinal herb: Review of species classification, pharmacology, active ingredient biosynthesis, and synthetic biology J. Adv. Res. (IF 11.4) Pub Date : 2024-11-16 Liwei Wu, Tingyu Ma, Chenxi Zang, Zhichao Xu, Wei Sun, Hongmei Luo, Meihua Yang, Jingyuan Song, Shilin Chen, Hui Yao
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Astragaloside IV alleviates septic myocardial injury through DUSP1-Prohibitin 2 mediated mitochondrial quality control and ER-autophagy J. Adv. Res. (IF 11.4) Pub Date : 2024-11-15 Junyan Wang, Xiangyi Pu, Haowen Zhuang, Zhijiang Guo, Mengyuan Wang, Huaihong Yang, Chun Li, Xing Chang
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2′-Fucosyllactose ameliorates aging-related osteoporosis by restoring gut microbial and innate immune homeostasis J. Adv. Res. (IF 11.4) Pub Date : 2024-11-14 Ang Li, Ruixin Kou, Jin Wang, Bowei Zhang, Yan Zhang, Jingmin Liu, Yaozhong Hu, Shuo Wang
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Oncogenic cholesterol rewires lipid metabolism in hepatocellular carcinoma via the CSNK2A1-IGF2R Ser2484 axis J. Adv. Res. (IF 11.4) Pub Date : 2024-11-14 Ren-yi Su, Chen-hao Xu, Hai-jun Guo, Li-jun Meng, Jian-yong Zhuo, Nan Xu, Hui-gang Li, Chi-yu He, Xuan-yu Zhang, Zheng-xin Lian, Shuai Wang, Chenhao Cao, Ruhong Zhou, Di Lu, Shu-sen Zheng, Xu-yong Wei, Xiao Xu
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Deficiency of myeloid NPC1 exacerbates liver injury and fibrosis by impairing macrophage efferocytosis J. Adv. Res. (IF 11.4) Pub Date : 2024-11-14 Dongwei Guan, Pengju Huang, Xinlei Liu, Qing Li, Xiaoxun Zhang, Nan Liu, Yong Wang, Ying Wan, Jin Chai, Shiying Cai, Rui Chen, Zhijia Ye
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Transformative applications of oculomics-based AI approaches in the management of systemic diseases: A systematic review J. Adv. Res. (IF 11.4) Pub Date : 2024-11-13 Zhongwen Li, Shiqi Yin, Shihong Wang, Yangyang Wang, Wei Qiang, Jiewei Jiang
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Host genetic regulation of specific functional groups in the rumen microbiome of dairy cows: Implications for lactation trait J. Adv. Res. (IF 11.4) Pub Date : 2024-11-12 Hao Bai, Zheng Lai, Jiawei Zhang, Xinyi Zheng, Jiyou Zhang, Wei Jin, Limei Lin, Shengyong Mao
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Lactate-mediated lactylation in human health and diseases: Progress and remaining challenges J. Adv. Res. (IF 11.4) Pub Date : 2024-11-09 Xue-ting Hu, Xiao-feng Wu, Jin-yi Xu, Xiang Xu
Lactate was once considered as metabolic waste for a long time. In 2019, Professor Zhao Yingming’s team from the University of Chicago found that lactate could also be used as a substrate to induce histone lactylation and regulate gene expression. Since then, researchers have discovered that lactate-mediated lactylation play important regulatory roles in various physiological and pathological processes
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Brain-targeted autoimmunity is strongly associated with Long COVID and its chronic fatigue syndrome as well as its affective symptoms J. Adv. Res. (IF 11.4) Pub Date : 2024-11-09 Abbas F. Almulla, Michael Maes, Bo Zhou, Hussein K. Al-Hakeim, Aristo Vojdani
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Biological functions and pharmacological behaviors of bile acids in metabolic diseases J. Adv. Res. (IF 11.4) Pub Date : 2024-11-08 Tongxi Zhuang, Xunjiang Wang, Zixuan Wang, Lihua Gu, Dawei Yue, Zhengtao Wang, Xiaohua Li, Li Yang, Wendong Huang, Lili Ding
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Advanced machine learning schemes for prediction CO2 flux based experimental approach in underground coal fire areas J. Adv. Res. (IF 11.4) Pub Date : 2024-11-07 Yongjun Wang, Mingze Guo, Hung Vo Thanh, Hemeng Zhang, Xiaoying Liu, Qian Zheng, Xiaoming Zhang, Mohammad Sh. Daoud, Laith Abualigah
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Increased Rab1a accelerates osteoarthritis by inhibiting autophagy via activation of the mTORC1-S6K pathway J. Adv. Res. (IF 11.4) Pub Date : 2024-11-07 Ze Chen, Mingze Tang, Zewei Wu, Yongcong Lin, Cuixi Wu, Hong Huang, Jianmao Chen, Zhaohua Zhu, Yongming Liu, Súan Tang, Changhai Ding, Weiyu Han
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Endothelial NMMHC IIA dissociation from PAR1 activates the CREB3/ARF4 signaling in thrombin-mediated intracerebral hemorrhage J. Adv. Res. (IF 11.4) Pub Date : 2024-11-07 Yujie Dai, Liangying Bao, Juan Huang, Miling Zhang, Junhe Yu, Yuanyuan Zhang, Fang Li, Boyang Yu, Shuaishuai Gong, Junping Kou
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Kaempferol alleviates myocardial ischemia injury by reducing oxidative stress via the HDAC3-mediated Nrf2 signaling pathway J. Adv. Res. (IF 11.4) Pub Date : 2024-11-05 Zejun Yue, Yirong Zhang, Wei Zhang, Nanbo Zheng, Jiazeng Wen, Lingxuan Ren, XiaoYu Rong, Liang Bai, Rong Wang, Sihai Zhao, Enqi Liu, Weirong Wang
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Bioinspired injectable hydrogels for bone regeneration J. Adv. Res. (IF 11.4) Pub Date : 2024-11-05 Xuan Tang, Fengjin Zhou, Sicheng Wang, Guangchao Wang, Long Bai, Jiacan Su
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Akt-FoxO signaling drives co-adaptation to insecticide and host plant stresses in an herbivorous insect J. Adv. Res. (IF 11.4) Pub Date : 2024-11-05 Huihui Zhang, Haoli Gao, Xumin Lin, Baojun Yang, Jingting Wang, Xiaowei Yuan, Zhen Zhang, Tianshun He, Zewen Liu
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TRPM2-mediated feed-forward loop promotes chondrocyte damage in osteoarthritis via calcium-cGAS-STING-NF-κB pathway J. Adv. Res. (IF 11.4) Pub Date : 2024-11-05 Kai Sun, Xiong Zhang, Liangcai Hou, Fan Lu, Haigang Liu, Zehang Zheng, Zhou Guo, Jingting Xu, Zhaoxuan Ruan, Yanjun Hou, Junchen He, Fengjing Guo, Kaixiang Yang
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A molecular perspective on the role of FERONIA in root growth, nutrient uptake, stress sensing and microbiome assembly J. Adv. Res. (IF 11.4) Pub Date : 2024-11-05 Sajad Ali, Anshika Tyagi, Suvin Park, Rajeev K. Varshney, Hanhong Bae
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Pan-genome analysis reveals genomic variations during enoki mushroom domestication, with emphasis on genetic signatures of cap color and stipe length J. Adv. Res. (IF 11.4) Pub Date : 2024-11-05 Fei Liu, Xin-Bin Ma, Bei Han, Bo Wang, Jian-Ping Xu, Bin Cao, Zhi-Lin Ling, Mao-Qiang He, Xin-Yu Zhu, Rui-Lin Zhao
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Tetrahydrocurcumin targets TRIP13 inhibiting the interaction of TRIP13/USP7/c-FLIP to mediate c-FLIP ubiquitination in triple-negative breast cancer J. Adv. Res. (IF 11.4) Pub Date : 2024-11-05 Yu-jie Sun, Qiang Zhang, Shi-jie Cao, Xiao-hu Sun, Ji-chao Zhang, Bing-yang Zhang, Ze-bin Shang, Chong-yan Zhao, Zhi-yong Cao, Qiu-ju Zhang, Xiu-mei Gao, Feng Qiu, Ning Kang
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Trichosanthin elicits antitumor activity via MICU3 mediated mitochondria calcium influx J. Adv. Res. (IF 11.4) Pub Date : 2024-11-04 Yunbin Zhang, Xuping Ding, Qian Zhang, Cong Zeng, Hongzhuan Chen, Liming Lu
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Mini and enhanced CRISPR activators for cancer therapies J. Adv. Res. (IF 11.4) Pub Date : 2024-11-03 Meiyu Huang, Keshan Wang, Anshu Li, Xiagu Zhu, Zuping Zhou, Chao Yang, Changhao Bi, Xueli Zhang
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Genetic associations of metabolic factors and therapeutic drug targets with polycystic ovary syndrome J. Adv. Res. (IF 11.4) Pub Date : 2024-11-01 Changlong Zhang, Yuxuan Li, Yang Wang, Shourui Hu, Yue Liu, Xiaofan Liang, Zi-Jiang Chen, Yuqing Zhang, Han Zhao
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scPerb: Predict single-cell perturbation via style transfer-based variational autoencoder J. Adv. Res. (IF 11.4) Pub Date : 2024-10-31 Zijia Tang, Minghao Zhou, Kai Zhang, Qianqian Song
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Biofortification of potato nutrition J. Adv. Res. (IF 11.4) Pub Date : 2024-10-30 Linxuan Li, Tingting Zhu, Lina Wen, Tanran Zhang, Maozhi Ren
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Synergistic potentiation of the anti-metastatic effect of a Ginseng-Salvia miltiorrhiza herbal pair and its biological ingredients via the suppression of CD62E-dependent neutrophil infiltration and NETformation J. Adv. Res. (IF 11.4) Pub Date : 2024-10-30 Keqin Lu, Yawen Xia, Peng Cheng, Yanan Li, Liang He, Li Tao, Zhonghong Wei, Yin Lu
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Chromosome-scale assembly with improved annotation provides insights into breed-wide genomic structure and diversity in domestic cats J. Adv. Res. (IF 11.4) Pub Date : 2024-10-28 Yuki Matsumoto, Claire Yik-Lok Chung, Sachiko Isobe, Mika Sakamoto, Xiao Lin, Ting-Fung Chan, Hideki Hirakawa, Genki Ishihara, Hon-Ming Lam, Shinobu Nakayama, Shigemi Sasamoto, Yasuhiro Tanizawa, Akiko Watanabe, Kei Watanabe, Masaru Yagura, Yoshihito Niimura, Yasukazu Nakamura
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Exerkine irisin mitigates cognitive impairment by suppressing gut-brain axis-mediated inflammation J. Adv. Res. (IF 11.4) Pub Date : 2024-10-29 Hu Zhang, Jiling Liang, Jielun Huang, Minghui Wang, Liangwen Wu, Tong Wu, Ning Chen
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Small-molecule targeting BCAT1-mediated BCAA metabolism inhibits the activation of SHOC2-RAS-ERK to induce apoptosis of Triple-negative breast cancer cells J. Adv. Res. (IF 11.4) Pub Date : 2024-10-28 Ling Huang, Guanjun Li, Ying Zhang, Ruishen Zhuge, Shijie Qin, Jinjun Qian, Ruixing Chen, Yin Kwan Wong, Huan Tang, Peili Wang, Wei Xiao, Jigang Wang
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Plasma proteomic profiles reveal proteins and three characteristic patterns associated with osteoporosis: A prospective cohort study J. Adv. Res. (IF 11.4) Pub Date : 2024-10-28 Yi Zheng, Jincheng Li, Yucan Li, Jiacheng Wang, Chen Suo, Yanfeng Jiang, Li Jin, Kelin Xu, Xingdong Chen
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Tailoring obeticholic acid activity by iridium(III) complex conjugation to develop a farnesoid X receptor probe J. Adv. Res. (IF 11.4) Pub Date : 2024-10-28 Dou Niu, Xiaolei Wu, Yuxin Zhang, Xueliang Wang, Daniel Shiu-Hin Chan, Shaozhen Jing, Chun-Yuen Wong, Wanhe Wang, Chung-Hang Leung
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Impaired stemness in aging periodontal ligament stem cells is mediated by the progerin/endoplasmic reticulum stress/p53 axis J. Adv. Res. (IF 11.4) Pub Date : 2024-10-28 Xige Zhang, Yazheng Wang, Jinjin Wang, Yang Zhang, Rui Li, Xiaoyu Wang, Xiaotong Ge, Qingyuan Ye, Jiyun Ji, Dongdong Fei, Qintao Wang
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Multiple roles of p53 in cancer development: Regulation of tumor microenvironment, m6A modification and diverse cell death mechanisms J. Adv. Res. (IF 11.4) Pub Date : 2024-10-28 Xiangyu Wang, Jianhua Yang, Wanting Yang, Haiyang Sheng, Buyun Jia, Peng Cheng, Shanshan Xu, Xinhui Hong, Chuanwei Jiang, Yinfeng Yang, Ziyin Wu, Jinghui Wang
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Dihydrokoumine, a dual-target analgesic with reduced side effects isolated from a traditional Chinese medicine J. Adv. Res. (IF 11.4) Pub Date : 2024-10-24 Dian Liu, Jixia Wang, Tao Hou, Yan Zhang, Han Zhou, Yaopeng Zhao, Liangliang Zhou, Cuiyan Cao, Yanfang Liu, Xinmiao Liang
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Neural and molecular investigation into the paraventricular thalamus for chronic restraint stress induced depressive-like behaviors J. Adv. Res. (IF 11.4) Pub Date : 2024-10-22 Yong He, Yikun Ren, Xiangyu Chen, Yue Wang, Heming Yu, Junchao Cai, Peng Wang, Yi Ren, Peng Xie
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Regulatory balance between ear rot resistance and grain yield and their breeding applications in maize and other crops J. Adv. Res. (IF 11.4) Pub Date : 2024-10-22 Zechao Yin, Xun Wei, Yanyong Cao, Zhenying Dong, Yan Long, Xiangyuan Wan
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Roles of oral and gut microbiota in acute myocardial infarction J. Adv. Res. (IF 11.4) Pub Date : 2024-10-22 Yu-Lin Li, Bo-Yan Chen, Ze-Hao Feng, Lu-Jun Zhou, Ting Liu, Wen-Zhen Lin, Hong Zhu, Shuo Xu, Xue-Bing Bai, Xiao-Qian Meng, Jun Zhang, Yan Liu, Jun Pu, Meng Jiang, Sheng-Zhong Duan
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Intra species dissection of phytophthora capsici resistance in black pepper J. Adv. Res. (IF 11.4) Pub Date : 2024-10-21 Yupeng Hao, Rui Fan, Yongyan Zhao, Ke Nie, Luyao Wang, Ting Zhao, Zhiyuan Zhang, Xiaoyuan Tao, Hongyu Wu, Jiaying Pan, Chaoyun Hao, Xueying Guan
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The gut microbiotas with metabolites regulate the protective role of miR-30a-5p in myocardial infarction J. Adv. Res. (IF 11.4) Pub Date : 2024-10-21 Ruiying Wang, Ruo-Lan Chen, Chan Wu, Xiao-Cheng Zhang, Wei-Yin Wu, Cuilian Dai, Yan Wang, Gang Li
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Achilles tendinopathy treatment via circadian rhythm regulation J. Adv. Res. (IF 11.4) Pub Date : 2024-10-21 Yibo Zhang, Yizhang Wu, Yong Wang, Jun Lu, Yang Lu, Peng Wang, Lan Li, Wenjin Yan, Hongling Cai, Weisbecker Hannah Leigh, Lin Zhang, Wubin Bai, Qing Jiang, Xingquan Xu
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Panaxatriol exerts anti-senescence effects and alleviates osteoarthritis and cartilage repair fibrosis by targeting UFL1 J. Adv. Res. (IF 11.4) Pub Date : 2024-10-21 Biao Kuang, Nana Geng, Miao Yi, Qiqi Zeng, Mengtian Fan, Menglin Xian, Lin Deng, Cheng Chen, Yiming Pan, Liang Kuang, Fengtao Luo, Yangli Xie, Chao Liu, Zhongliang Deng, Mao Nie, Yu Du, Fengjin Guo
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Pleiotropic role of CCR9/CCL25 signaling in adriamycin-induced cardiomyopathy J. Adv. Res. (IF 11.4) Pub Date : 2024-10-21 Xue Wu, Zheng Wang, Zhenxing Liang, Ning Li, Junmin Chen, Qiong Liu, Wangrui Lei, Xiaopeng Wu, Chenxi Lu, Chao Deng, Ying Chen, Xue Wang, Jinhong Wei, Yang Yang
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Contribution of Pseudomonas aeruginosa − mediated club cell necroptosis to the bias of type 17 inflammation and steroid insensitivity in asthma J. Adv. Res. (IF 11.4) Pub Date : 2024-10-21 Jieying Guan, Wenruo Yao, Le Zhang, Huancheng Xie, Linmei Li, Yuhuan Wen, Honglv Chen, Yuyi Huang, Junjie Wen, Changxing Ou, Canyang Liang, Jing Wang, Qingling Zhang, Ailin Tao, Jie Yan
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New insights into the enteric methane production based on the archaeal genome atlas of ruminant gastrointestinal tract J. Adv. Res. (IF 11.4) Pub Date : 2024-10-18 Yifan Tang, Xiaohan Liu, Senlin Zhu, Minghui Jia, Jian-Xin Liu, Hui-Zeng Sun
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The fatty acid receptor CD36 promotes macrophage infiltration via p110γ signaling to stimulate metastasis J. Adv. Res. (IF 11.4) Pub Date : 2024-10-16 Hong Qin, Anhua Xiao, Qiannan Lu, Yiyu Li, Xiaoqing Luo, Enze Zheng, Chuan Tian, Huan Liu, Xiaoya Zheng, Li Wei, Xiong Z Ruan, Ping Yang, Yaxi Chen
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Single-cell transcriptomic profiling uncovers cellular complexity and microenvironment in gastric tumorigenesis associated with Helicobacter pylori J. Adv. Res. (IF 11.4) Pub Date : 2024-10-15 Nianshuang Li, Sihai Chen, Xinbo Xu, Huan Wang, Pan Zheng, Xiao Fei, Huajing Ke, Yuting Lei, Yanan Zhou, Xiaoyu Yang, Yaobin Ouyang, Chuan Xie, Cong He, Yi Hu, Yi Cao, Zhengrong Li, Yong Xie, Zhongming Ge, Xu Shu, Nonghua Lu, Jianping Liu, Yin Zhu
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Metabolic responses of sea anemone and jellyfish to temperature and UV bleaching: Insights into stress adaptation using LCMS-based metabolomics, molecular networking and chemometrics J. Adv. Res. (IF 11.4) Pub Date : 2024-10-15 Mohamed A. Farag, Doaa B. Saied, Sherif M. Afifi, Andreas Kunzmann, Ludger A. Wessjohann, Hildegard Westphal, Holger Kühnhold, Marleen Stuhr
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Graphdiyne as an emerging sensor platform: Principles, synthesis and application J. Adv. Res. (IF 11.4) Pub Date : 2024-10-15 Wei Zhang, Jing Xu, Tian Wang, Xi Lin, Fu Wang
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Ecological consequences of antimicrobial residues and bioactive chemicals on antimicrobial resistance in agroecosystems J. Adv. Res. (IF 11.4) Pub Date : 2024-10-15 Muhammad Shafiq, Charles Obinwanne Okoye, Mudasir Nazar, Wajid Ali Khattak, Abdelazeem M. Algammal
更新日期：2024-11-13
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