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2′-Fucosyllactose ameliorates aging-related osteoporosis by restoring gut microbial and innate immune homeostasis
Journal of Advanced Research ( IF 11.4 ) Pub Date : 2024-11-14 , DOI: 10.1016/j.jare.2024.11.017 Ang Li, Ruixin Kou, Jin Wang, Bowei Zhang, Yan Zhang, Jingmin Liu, Yaozhong Hu, Shuo Wang
Journal of Advanced Research ( IF 11.4 ) Pub Date : 2024-11-14 , DOI: 10.1016/j.jare.2024.11.017 Ang Li, Ruixin Kou, Jin Wang, Bowei Zhang, Yan Zhang, Jingmin Liu, Yaozhong Hu, Shuo Wang
Aging-related osteoporosis is considered as a serious public health concern for middle-aged and elderly people, with an intricated pathogenesis including the recently identified aging-induced immunological dysfunction and gut microbial disorder. The intervention based on dietary prebiotics is recommended to retain bone health and postpone the progression of osteoporosis.
中文翻译:
2'-岩藻糖基乳糖通过恢复肠道微生物和先天免疫稳态来改善与衰老相关的骨质疏松症
衰老相关骨质疏松症被认为是中老年人严重的公共卫生问题,其发病机制错综复杂,包括最近发现的衰老诱导的免疫功能障碍和肠道微生物疾病。建议基于膳食益生元的干预以保持骨骼健康并延缓骨质疏松症的进展。
更新日期:2024-11-14
中文翻译:
2'-岩藻糖基乳糖通过恢复肠道微生物和先天免疫稳态来改善与衰老相关的骨质疏松症
衰老相关骨质疏松症被认为是中老年人严重的公共卫生问题,其发病机制错综复杂,包括最近发现的衰老诱导的免疫功能障碍和肠道微生物疾病。建议基于膳食益生元的干预以保持骨骼健康并延缓骨质疏松症的进展。