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Advanced machine learning schemes for prediction CO2 flux based experimental approach in underground coal fire areas J. Adv. Res. (IF 11.4) Pub Date : 2024-11-07 Yongjun Wang, Mingze Guo, Hung Vo Thanh, Hemeng Zhang, Xiaoying Liu, Qian Zheng, Xiaoming Zhang, Mohammad Sh. Daoud, Laith Abualigah
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Increased Rab1a accelerates osteoarthritis by inhibiting autophagy via activation of the mTORC1-S6K pathway J. Adv. Res. (IF 11.4) Pub Date : 2024-11-07 Ze Chen, Mingze Tang, Zewei Wu, Yongcong Lin, Cuixi Wu, Hong Huang, Jianmao Chen, Zhaohua Zhu, Yongming Liu, Súan Tang, Changhai Ding, Weiyu Han
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Endothelial NMMHC IIA dissociation from PAR1 activates the CREB3/ARF4 signaling in thrombin-mediated intracerebral hemorrhage J. Adv. Res. (IF 11.4) Pub Date : 2024-11-07 Yujie Dai, Liangying Bao, Juan Huang, Miling Zhang, Junhe Yu, Yuanyuan Zhang, Fang Li, Boyang Yu, Shuaishuai Gong, Junping Kou
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Akt-FoxO signaling drives co-adaptation to insecticide and host plant stresses in an herbivorous insect J. Adv. Res. (IF 11.4) Pub Date : 2024-11-05 Huihui Zhang, Haoli Gao, Xumin Lin, Baojun Yang, Jingting Wang, Xiaowei Yuan, Zhen Zhang, Tianshun He, Zewen Liu
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TRPM2-mediated feed-forward loop promotes chondrocyte damage in osteoarthritis via calcium-cGAS-STING-NF-κB pathway J. Adv. Res. (IF 11.4) Pub Date : 2024-11-05 Kai Sun, Xiong Zhang, Liangcai Hou, Fan Lu, Haigang Liu, Zehang Zheng, Zhou Guo, Jingting Xu, Zhaoxuan Ruan, Yanjun Hou, Junchen He, Fengjing Guo, Kaixiang Yang
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Kaempferol alleviates myocardial ischemia injury by reducing oxidative stress via the HDAC3-mediated Nrf2 signaling pathway J. Adv. Res. (IF 11.4) Pub Date : 2024-11-05 Zejun Yue, Yirong Zhang, Wei Zhang, Nanbo Zheng, Jiazeng Wen, Lingxuan Ren, XiaoYu Rong, Liang Bai, Rong Wang, Sihai Zhao, Enqi Liu, Weirong Wang
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A molecular perspective on the role of FERONIA in root growth, nutrient uptake, stress sensing and microbiome assembly J. Adv. Res. (IF 11.4) Pub Date : 2024-11-05 Sajad Ali, Anshika Tyagi, Suvin Park, Rajeev K. Varshney, Hanhong Bae
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Bioinspired injectable hydrogels for bone regeneration J. Adv. Res. (IF 11.4) Pub Date : 2024-11-05 Xuan Tang, Fengjin Zhou, Sicheng Wang, Guangchao Wang, Long Bai, Jiacan Su
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Pan-genome analysis reveals genomic variations during enoki mushroom domestication, with emphasis on genetic signatures of cap color and stipe length J. Adv. Res. (IF 11.4) Pub Date : 2024-11-05 Fei Liu, Xin-Bing Ma, Bei Han, Bo Wang, Jian-Ping Xu, Bin Cao, Zhi-Lin Ling, Mao-Qiang He, Xin-Yu Zhu, Rui-Lin Zhao
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Tetrahydrocurcumin targets TRIP13 inhibiting the interaction of TRIP13/USP7/c-FLIP to mediate c-FLIP ubiquitination in triple-negative breast cancer J. Adv. Res. (IF 11.4) Pub Date : 2024-11-05 Yu-jie Sun, Qiang Zhang, Shi-jie Cao, Xiao-hu Sun, Ji-chao Zhang, Bing-yang Zhang, Ze-bin Shang, Chong-yan Zhao, Zhi-yong Cao, Qiu-ju Zhang, Xiu-mei Gao, Feng Qiu, Ning Kang
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Trichosanthin elicits antitumor activity via MICU3 mediated mitochondria calcium influx J. Adv. Res. (IF 11.4) Pub Date : 2024-11-04 Yunbin Zhang, Xuping Ding, Qian Zhang, Cong Zeng, Hongzhuan Chen, Liming Lu
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Mini and enhanced CRISPR activators for cancer therapies J. Adv. Res. (IF 11.4) Pub Date : 2024-11-03 Meiyu Huang, Keshan Wang, Anshu Li, Xiagu Zhu, Zuping Zhou, Chao Yang, Changhao Bi, Xueli Zhang
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Genetic associations of metabolic factors and therapeutic drug targets with polycystic ovary syndrome J. Adv. Res. (IF 11.4) Pub Date : 2024-11-01 Changlong Zhang, Yuxuan Li, Yang Wang, Shourui Hu, Yue Liu, Xiaofan Liang, Zi-Jiang Chen, Yuqing Zhang, Han Zhao
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scPerb: Predict single-cell perturbation via style transfer-based variational autoencoder J. Adv. Res. (IF 11.4) Pub Date : 2024-10-31 Zijia Tang, Minghao Zhou, Kai Zhang, Qianqian Song
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Biofortification of potato nutrition J. Adv. Res. (IF 11.4) Pub Date : 2024-10-30 Linxuan Li, Tingting Zhu, Lina Wen, Tanran Zhang, Maozhi Ren
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Synergistic potentiation of the anti-metastatic effect of a Ginseng-Salvia miltiorrhiza herbal pair and its biological ingredients via the suppression of CD62E-dependent neutrophil infiltration and NET formation J. Adv. Res. (IF 11.4) Pub Date : 2024-10-30 Keqin Lu, Yawen Xia, Peng Cheng, Yanan Li, Liang He, Li Tao, Zhonghong Wei, Yin Lu
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Exerkine irisin mitigates cognitive impairment by suppressing gut-brain axis-mediated inflammation J. Adv. Res. (IF 11.4) Pub Date : 2024-10-29 Hu Zhang, Jiling Liang, Jielun Huang, Minghui Wang, Liangwen Wu, Tong Wu, Ning Chen
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Plasma proteomic profiles reveal proteins and three characteristic patterns associated with osteoporosis: A prospective cohort study J. Adv. Res. (IF 11.4) Pub Date : 2024-10-28 Yi Zheng, Jincheng Li, Yucan Li, Jiacheng Wang, Chen Suo, Yanfeng Jiang, Li Jin, Kelin Xu, Xingdong Chen
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Chromosome-scale assembly with improved annotation provides insights into breed-wide genomic structure and diversity in domestic cats J. Adv. Res. (IF 11.4) Pub Date : 2024-10-28 Yuki Matsumoto, Claire Yik-Lok Chung, Sachiko Isobe, Mika Sakamoto, Xiao Lin, Ting-Fung Chan, Hideki Hirakawa, Genki Ishihara, Hon-Ming Lam, Shinobu Nakayama, Shigemi Sasamoto, Yasuhiro Tanizawa, Akiko Watanabe, Kei Watanabe, Masaru Yagura, Yoshihito Niimura, Yasukazu Nakamura
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Tailoring obeticholic acid activity by iridium(III) complex conjugation to develop a farnesoid X receptor probe J. Adv. Res. (IF 11.4) Pub Date : 2024-10-28 Dou Niu, Xiaolei Wu, Yuxin Zhang, Xueliang Wang, Daniel Shiu-Hin Chan, Shaozhen Jing, Chun-Yuen Wong, Wanhe Wang, Chung-Hang Leung
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Small-molecule targeting BCAT1-mediated BCAA metabolism inhibits the activation of SHOC2-RAS-ERK to induce apoptosis of Triple-negative breast cancer cells J. Adv. Res. (IF 11.4) Pub Date : 2024-10-28 Ling Huang, Guanjun Li, Ying Zhang, Ruishen Zhuge, Shijie Qin, Jinjun Qian, Ruixing Chen, Yin Kwan Wong, Huan Tang, Peili Wang, Wei Xiao, Jigang Wang
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Impaired stemness in aging periodontal ligament stem cells is mediated by the progerin/endoplasmic reticulum stress/p53 axis J. Adv. Res. (IF 11.4) Pub Date : 2024-10-28 Xige Zhang, Yazheng Wang, Jinjin Wang, Yang Zhang, Rui Li, Xiaoyu Wang, Xiaotong Ge, Qingyuan Ye, Jiyun Ji, Dongdong Fei, Qintao Wang
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Multiple roles of p53 in cancer development: Regulation of tumor microenvironment, m6A modification and diverse cell death mechanisms J. Adv. Res. (IF 11.4) Pub Date : 2024-10-28 Xiangyu Wang, Jianhua Yang, Wanting Yang, Haiyang Sheng, Buyun Jia, Peng Cheng, Shanshan Xu, Xinhui Hong, Chuanwei Jiang, Yinfeng Yang, Ziyin Wu, Jinghui Wang
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Dihydrokoumine, a dual-target analgesic with reduced side effects isolated from a traditional Chinese medicine J. Adv. Res. (IF 11.4) Pub Date : 2024-10-24 Dian Liu, Jixia Wang, Tao Hou, Yan Zhang, Han Zhou, Yaopeng Zhao, Liangliang Zhou, Cuiyan Cao, Yanfang Liu, Xinmiao Liang
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Neural and molecular investigation into the paraventricular thalamus for chronic restraint stress induced depressive-like behaviors J. Adv. Res. (IF 11.4) Pub Date : 2024-10-22 Yong He, Yikun Ren, Xiangyu Chen, Yue Wang, Heming Yu, Junchao Cai, Peng Wang, Yi Ren, Peng Xie
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Regulatory balance between ear rot resistance and grain yield and their breeding applications in maize and other crops J. Adv. Res. (IF 11.4) Pub Date : 2024-10-22 Zechao Yin, Xun Wei, Yanyong Cao, Zhenying Dong, Yan Long, Xiangyuan Wan
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Roles of oral and gut microbiota in acute myocardial infarction J. Adv. Res. (IF 11.4) Pub Date : 2024-10-22 Yu-Lin Li, Bo-Yan Chen, Ze-Hao Feng, Lu-Jun Zhou, Ting Liu, Wen-Zhen Lin, Hong Zhu, Shuo Xu, Xue-Bing Bai, Xiao-Qian Meng, Jun Zhang, Yan Liu, Jun Pu, Meng Jiang, Sheng-Zhong Duan
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The gut microbiotas with metabolites regulate the protective role of miR-30a-5p in myocardial infarction J. Adv. Res. (IF 11.4) Pub Date : 2024-10-21 Ruiying Wang, Ruo-Lan Chen, Chan Wu, Xiao-Cheng Zhang, Wei-Yin Wu, Cuilian Dai, Yan Wang, Gang Li
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Intra species dissection of phytophthora capsici resistance in black pepper J. Adv. Res. (IF 11.4) Pub Date : 2024-10-21 Yupeng Hao, Rui Fan, Yongyan Zhao, Ke Nie, Luyao Wang, Ting Zhao, Zhiyuan Zhang, Xiaoyuan Tao, Hongyu Wu, Jiaying Pan, Chaoyun Hao, Xueying Guan
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Achilles tendinopathy treatment via circadian rhythm regulation J. Adv. Res. (IF 11.4) Pub Date : 2024-10-21 Yibo Zhang, Yizhang Wu, Yong Wang, Jun Lu, Yang Lu, Peng Wang, Lan Li, Wenjin Yan, Hongling Cai, Weisbecker Hannah Leigh, Lin Zhang, Wubin Bai, Qing Jiang, Xingquan Xu
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Panaxatriol exerts anti-senescence effects and alleviates osteoarthritis and cartilage repair fibrosis by targeting UFL1 J. Adv. Res. (IF 11.4) Pub Date : 2024-10-21 Biao Kuang, Nana Geng, Miao Yi, Qiqi Zeng, Mengtian Fan, Menglin Xian, Lin Deng, Cheng Chen, Yiming Pan, Liang Kuang, Fengtao Luo, Yangli Xie, Chao Liu, Zhongliang Deng, Mao Nie, Yu Du, Fengjin Guo
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Pleiotropic role of CCR9/CCL25 signaling in adriamycin-induced cardiomyopathy J. Adv. Res. (IF 11.4) Pub Date : 2024-10-21 Xue Wu, Zheng Wang, Zhenxiang Liang, Ning Li, Junmin Chen, Qiong Liu, Wangrui Lei, Xiaopeng Wu, Chenxi Lu, Chao Deng, Ying Chen, Xue Wang, Jinhong Wei, Yang Yang
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Contribution of Pseudomonas aeruginosa − mediated club cell necroptosis to the bias of type 17 inflammation and steroid insensitivity in asthma J. Adv. Res. (IF 11.4) Pub Date : 2024-10-21 Jieying Guan, Wenruo Yao, Le Zhang, Huancheng Xie, Linmei Li, Yuhuan Wen, Honglv Chen, Yuyi Huang, Junjie Wen, Changxing Ou, Canyang Liang, Jing Wang, Qingling Zhang, Ailin Tao, Jie Yan
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New insights into the enteric methane production based on the archaeal genome map of ruminant gastrointestinal tract J. Adv. Res. (IF 11.4) Pub Date : 2024-10-18 Yifan Tang, Xiaohan Liu, Senlin Zhu, Minghui Jia, Jian-Xin Liu, Hui-Zeng Sun
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The fatty acid receptor CD36 promotes macrophage infiltration via p110γ signaling to stimulate metastasis J. Adv. Res. (IF 11.4) Pub Date : 2024-10-16 Hong Qin, Anhua Xiao, Qiannan Lu, Yiyu Li, Xiaoqing Luo, Enze Zheng, Chuan Tian, Huan Liu, Xiaoya Zheng Resource, Li Wei, Xiong Z Ruan, Ping Yang, Yaxi Chen
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Single-cell transcriptomic profiling uncovers cellular complexity and microenvironment in gastric tumorigenesis associated with Helicobacter pylori J. Adv. Res. (IF 11.4) Pub Date : 2024-10-15 Nianshuang Li, Sihai Chen, Xinbo Xu, Huan Wang, Pan Zheng, Xiao Fei, Huajing Ke, Yuting Lei, Yanan Zhou, Xiaoyu Yang, Yaobin Ouyang, Chuan Xie, Cong He, Yi Hu, Yi Cao, Zhengrong Li, Yong Xie, Zhongming Ge, Xu Shu, Nonghua Lu, Yin Zhu
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Metabolic responses of sea anemone and jellyfish to temperature and UV bleaching: Insights into stress adaptation using LCMS-based metabolomics, molecular networking and chemometrics J. Adv. Res. (IF 11.4) Pub Date : 2024-10-15 Mohamed A. Farag, Doaa B. Saied, Sherif M. Afifi, Andreas Kunzmann, Ludger A. Wessjohann, Hildegard Westphal, Holger Kühnhold, Marleen Stuhr
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Graphdiyne as an emerging sensor platform: Principles, synthesis and application J. Adv. Res. (IF 11.4) Pub Date : 2024-10-15 Wei Zhang, Jing Xu, Tian Wang, Xi Lin, Fu Wang
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Ecological consequences of antimicrobial residues and bioactive chemicals on antimicrobial resistance in agroecosystems J. Adv. Res. (IF 11.4) Pub Date : 2024-10-15 Muhammad Shafiq, Charles Obinwanne Okoye, Mudasir Nazar, Wajid Ali Khattak, Abdelazeem M. Algammal
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Mass spectrometry unveils heat-induced changes in yolk oxylipins and key lipid molecules during home cooking J. Adv. Res. (IF 11.4) Pub Date : 2024-10-15 Wenting Li, Nian Wang, Xin Lv, Dan Wang, Hong Chen, Fang Wei
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Applications of single-cell analysis in immunotherapy for lung cancer: Current progress, new challenges and expectations J. Adv. Res. (IF 11.4) Pub Date : 2024-10-12 Nan Xiao, Hongyang Liu, Chenxing Zhang, Huanxiang Chen, Yang Li, Ying Yang, Hongchun Liu, Junhu Wan
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Food inflammation index reveals the key inflammatory components in foods and heterogeneity within food groups: How do we choose food? J. Adv. Res. (IF 11.4) Pub Date : 2024-10-12 Zhangtie Wang, Changzheng Yuan, Yansong Zhang, Nesma S. Abdelaty, Cheng Chen, Jianfu Shen, Liangxiao Zhang, Baiyi Lu, Ruihai Liu, Peiwu Li
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Integrated stress response activation induced by usnic acid alleviates BCL-2 inhibitor ABT-199 resistance in acute myeloid leukemia J. Adv. Res. (IF 11.4) Pub Date : 2024-10-09 Dijiong Wu, Man Li, Yaonan Hong, Li Jin, Qi Liu, Chengtao Sun, Liqin Li, Xiaoxiao Han, Shengqian Deng, Yue Feng, Yiping Shen, Guoyin Kai
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Activity-based protein profiling guided new target identification of quinazoline derivatives for expediting bactericide discovery: Activity-based protein profiling derived new target discovery of antibacterial quinazolines J. Adv. Res. (IF 11.4) Pub Date : 2024-10-09 Jiao Meng, Ling Zhang, Xinxin Tuo, Yue Ding, Kunlun Chen, Mei Li, Biao Chen, Qingsu Long, Zhenchao Wang, Guiping Ouyang, Xiang Zhou, Song Yang
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Effect of mitochondrial translocator protein TSPO on LPS-induced cardiac dysfunction J. Adv. Res. (IF 11.4) Pub Date : 2024-10-09 Xingyue Li, Xiao Chen, Feng-yuan Yang, Tingting Shu, Lintao Jiang, Bo He, Ming Tang, Xingbing Li, Dandong Fang, Pedro A. Jose, Yu Han, Yongjian Yang, Chunyu Zeng
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Elevated muramyl dipeptide by sialic acid-facilitated postantibiotic pathobiont expansion contributes to gut dysbiosis-induced mastitis in mice J. Adv. Res. (IF 11.4) Pub Date : 2024-10-05 Min Qiu, Cong Ye, Lijuan Bao, Keyi Wu, Yihong Zhao, Xiaotong Zhao, Ruibo Tang, Ruping Shang, Shan Shang, Chongshan Yuan, Xiaoyu Hu, Naisheng Zhang, Yunhe Fu, Jun Wang, Caijun Zhao
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Hippocampal dipeptidyl peptidase 9 bidirectionally regulates memory associated with synaptic plasticity J. Adv. Res. (IF 11.4) Pub Date : 2024-10-05 Ya-Bo Zhao, Shi-Zhe Wang, Wen-Ting Guo, Le Wang, Xun Tang, Jin-Nan Li, Lin Xu, Qi-Xin Zhou
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Columbianadin ameliorates rheumatoid arthritis by attenuating synoviocyte hyperplasia through targeted vimentin to inhibit the VAV2/Rac-1 signaling pathway J. Adv. Res. (IF 11.4) Pub Date : 2024-10-05 Yuli Han, Changqing Liu, Shujing Chen, Huihui Sun, Zhaoyu Jia, Jiaxin Shi, Lirong Wang, Kunze Du, Yanxu Chang
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Serum metabolite biomarkers for the early diagnosis and monitoring of age-related macular degeneration J. Adv. Res. (IF 11.4) Pub Date : 2024-10-05 Shengjie Li, Yichao Qiu, Yingzhu Li, Jianing Wu, Ning Yin, Jun Ren, Mingxi Shao, Jian Yu, Yunxiao Song, Xinghuai Sun, Shunxiang Gao, Wenjun Cao
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The role of JNK signaling pathway in organ fibrosis J. Adv. Res. (IF 11.4) Pub Date : 2024-10-02 Zhouhui Yao, Yandan Lu, Pingping Wang, Ziyan Chen, Licheng Zhou, Xianan Sang, Qiao Yang, Kuilong Wang, Min Hao, Gang Cao
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Unravelling the role of WRKY transcription factors in leaf senescence: Genetic and molecular insights J. Adv. Res. (IF 11.4) Pub Date : 2024-10-01 Zishan Ahmad, Muthusamy Ramakrishnan, Chunyue Wang, Shamsur Rehman, Anwar Shahzad, Qiang Wei
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Pharmacological upregulation of macrophage-derived itaconic acid by pubescenoside C attenuated myocardial ischemia–reperfusion injury J. Adv. Res. (IF 11.4) Pub Date : 2024-09-30 Sixuan Chen, Haojie Yao, Yanmei Lou, Huihui Wang, Baoping Xie, Junxuan Wu, Xiaoxiao Qi, Ying Wang, Peng Wu, Rong Zhang, Zhongqiu Liu, Yuanyuan Cheng
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Population genomics analyses reveal the role of hybridization in the rapid invasion of fall armyworm J. Adv. Res. (IF 11.4) Pub Date : 2024-09-30 Xuan Wang, Zhenyong Du, Yuange Duan, Shanlin Liu, Jie Liu, Bingyan Li, Ling Ma, Yunfei Wu, Li Tian, Fan Song, Wanzhi Cai, Hu Li
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Salidroside sensitizes Triple-negative breast cancer to ferroptosis by SCD1-mediated lipogenesis and NCOA4-mediated ferritinophagy J. Adv. Res. (IF 11.4) Pub Date : 2024-09-29 Guiqin Huang, Yawen Cai, Menghui Ren, Xiaoyu Zhang, Yu Fu, Run Cheng, Yingdi Wang, Mingxing Miao, Lingpeng Zhu, Tianhua Yan
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Gastrodin attenuates high fructose-induced sweet taste preference decrease by inhibiting hippocampal neural stem cell ferroptosis J. Adv. Res. (IF 11.4) Pub Date : 2024-09-29 Chuan-Feng Tang, Hong Ding, Ya-Qian Wu, Zi-An Miao, Zi-Xuan Wang, Wen-Xuan Wang, Ying Pan, Ling-Dong Kong
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A multi-omics approach reveals that lotus root polysaccharide iron ameliorates iron deficiency-induced testicular damage by activating PPARγ to promote steroid hormone synthesis J. Adv. Res. (IF 11.4) Pub Date : 2024-09-28 Pei-Yu Dong, Shuai Yuan, Yu-Mei Chen Yan, Yu Chen, Yue Bai, Yang Dong, Yin-Yin Li, Wei Shen, Xi-Feng Zhang
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A novel effect of sulforaphane on promoting mouse granulosa cells proliferation via the NRF2–TKT pathway J. Adv. Res. (IF 11.4) Pub Date : 2024-09-27 Xuan Zhang, Dingding Zhang, Aoyun Fan, Xinyi Zhou, Caixia Yang, Jiaqi Zhou, Ming Shen, Honglin Liu, Kang Zou, Jingli Tao