In Mediterranean countries like Cyprus, extreme temperatures and especially heatwaves during summer months are increasingly common, leading to heightened bio-climatic stress. While coldwaves are less frequent and understudied in this region, they still pose significant health risks. This study utilizes temperature data from ERA5–Land in conjunction with mortality and hospitalisation data from Cyprus

Heat exposure has been identified as a significant contributory factor in the development of cardiovascular diseases, but the biological mechanisms are not yet fully elucidated. We conducted a randomized crossover trial in healthy adults in Shanghai, China. Each subject was alternatively exposed to moderate temperature (22℃) and elevated temperature (32℃) in a chamber for 2 h in random order. Blood

The authors of the article with the title “Effects of radiofrequency electromagnetic field (RF-EMF) exposure on male fertility: A systematic review of experimental studies on non-human mammals and human sperm in vitro” regret to report a few inconsistencies detected in the article after its publication, due to errors that inadvertently occurred in the extraction of the original data and in the misfiling

Exposure to fine particulate matter (PM2.5) from wildfire smoke has been linked to immune dysregulation underlying multiple health conditions, but data on the long-term effects of these exposures during gestation are lacking. Smoke PM2.5 from wildfires occurring in urban areas is of particular concern because it can carry persistent chemicals within household furniture or soil, as well as polyaromatic

Antimicrobial resistance (AMR) is a major threat to human, animal, and crop health. AMR can be directly selected for by antibiotics, and indirectly co-selected for by biocides and metals, at environmentally relevant concentrations. Some evidence suggests that non-antibiotic drugs (NADs) can co-select for AMR, but previous work focused on exposing single model bacterial species to predominately high

The rapid escalation of antibiotic resistance of pathogenic bacteria has become a critical global public health threat. Despite the extensive use of antibiotics in medicine, debates on the origins of antibiotic-resistance pathogenic bacterium remain unresolved. In this study, five antibiotic-resistant pathogenic bacteria (S. epidermidis, S. warneri, A. viridans, B. cereus or S. haemolyticus), which

BackgroundUrban heat island (UHI), attributed to rapid urbanization, might be a latent modifiable risk factor for human health, yet little is known about whether UHI puts a strain on public mental health. This study aimed to assess the effect of the summer UHI on mental health. MethodsLeveraging 338,363 urban residents from the UK Biobank, this study estimated the associations of summer UHI effect

Evidence on the combined impact of air pollution and lifestyle on cardiovascular disease (CVD) risk is limited. We employed the Space-Time Extra-Trees model, an ensemble learning method for spatiotemporal data, to estimate the annual average concentrations of five air pollutants from 2017 to 2019. Cox proportional hazards models were used to assess the associations between air pollutant exposure and

An increasing body of evidence indicates that exposure to widespread, environmental and food contaminants such as mycotoxins may cause endocrine disorders and infertility. Deoxynivalenol (DON), which is a toxic secondary metabolite produced by Fusarium fungi, can lead to multiple harmful effects in humans and animals, such as hepatotoxicity, nephrotoxicity, immunotoxicity, gastrointestinal toxicity

Bisphenol S (BPS) has become extensively used in the manufacturing of consumer products. BPS mainly enters the body through food and water, with oral exposure targeting the gastrointestinal tract. However, its safety profile remains contentious and warrants further investigation. In this study, we aimed to assess whether BPS exerts harmful effects on the body in the absence of overt pathological damage

ObjectiveGlyphosate is the most widely used pesticide worldwide. Few epidemiologic studies have examined the potential for neurotoxicity by glyphosate or its degradate, aminomethylphosphonic acid (AMPA). We examined associations of maternal urinary glyphosate and AMPA concentrations with child cognitive, social, and behavioural functioning in participants enrolled in the Maternal-Infant Research on

Aflatoxins are mycotoxins produced by Aspergillus fungi in crops intended for food and feed. Acute exposure to high levels of aflatoxin B1, one of the most toxic mycotoxins, can result in severe poisoning, defined as acute aflatoxicosis, which manifests as acute hepatic failure followed by death in severe cases. Currently global burden estimates of acute aflatoxicosis are lacking – in contrast to burden

Mapping urban pollution is essential for assessing population exposure and addressing associated health impacts. High urban concentrations are due to the proximity of sources such as traffic or residential heating, and to urban density with the presence of buildings that reduce street ventilation. This urban complexity makes fine-scale mapping challenging, even for regulated pollutants such as NO2

Previous studies observed predominantly positive associations between the amount of nearby green space and a variety of health outcomes. Although nearness is assumed to be an important aspect of this association, the presence of own private green space is rarely studied. We investigated cross-sectional associations between the amount of domestic garden greenery and the prevalence of 21 health conditions

This study investigated the influence of three indoor environmental parameters: ventilation (expressed as air exchange rate, h−1), temperature, and relative humidity, on phthalate concentration in dust and in estimated airborne. We monitored environmental parameters and collected dust samples in 327 bedrooms in Tianjin, China. Air exchange rates were estimated using occupants-generated CO2 as a tracer

The intestinal microbiome is essential for gastrointestinal and overall health, yet its response to air pollution in children remains underexplored. In a study involving 412 young children from the ENVIRONAGE cohort, stool samples were analysed via Illumina Miseq sequencing to assess microbiome alpha diversity (observed richness, species evenness, and Shannon diversity) and composition. Exposure to

Microplastic (MP) pollution has become a widespread environmental threat which must be addressed as it affects the water bodies, soil as well as air. MPs originally from synthetic textiles, tire abrasion, plastic waste, etc. pose the significant risks to both the environment and health due to its structure, ability to absorb toxins and act as carriers of harmful substances. This characteristic enables

Menstrual and intimate care products (MICPs) such as tampons, menstrual pads, menstrual cups, and adult novelties are widely used worldwide for women’s menstrual comfort or pleasure, respectively. However, growing consumer concerns regarding the presence of hazardous chemicals in these products have been raised.

Previous studies suggest that per- and polyfluoroalkyl substances (PFAS) may act as immune suppressants. However, research about the impact of PFAS exposure on antibody responses to the measles, mumps, rubella (MMR) vaccine is limited and inconsistent.

Carbonaceous aerosol components (CACs) significantly influence global radiative forcing and human health. We developed a simultaneous inversion algorithm for four CACs: black carbon (BC), brown carbon (BrC), water-soluble organic matter (WSOM), and water-insoluble organic matter (WIOM), considering their distinct optical, solubility, and hygroscopicity properties. Using AERONET data, we inverted the

Although per- and polyfluoroalkyl substances (PFAS) have raised global concern due to their adverse effects on children’s development, the association between prenatal exposure to PFAS and the achievement of developmental milestones in preschool children remains unclear. This study aimed to examine the individual and cumulative associations between prenatal PFAS and developmental delay in 4-year-old

Little is known about how temperature variability (TV) affects the risk of preterm birth (PTB).