What does a postcolonial inquiry into technoscience do? And what is it for? I develop these questions by reconsidering one powerful idea: that science and technology studies (STS) is postcolonial when it elucidates the hybridity, heterogeneity, and indeterminacy of global technoscientific formations, and does so to falsify colonial fantasies of hegemony expressed in imperious conceptual generalities

This article explores the development of T cell-based therapies in Switzerland. These therapies, which elicit the immunological potential of each patient to respond to tumor development, constitute a major promise for so-called ‘precision oncology’. We document how immunological concepts, technologies, and practices are articulated given the centrality of genomics in ‘precision oncology’. We consider

When the future is connected to the term ‘imagination’, it is generally presented through the concept of the ‘imaginary’—that is, an image of the future that is related to a grand social image. In this article, we discuss the concept of sociotechnical imaginaries and argue that although this concept provides a needed perspective that allows scholars to unpack imaginaries associated with technological

Non-fungible tokens (NFTs) are novel techno-economic configurations underpinned by cryptocurrency ledgers that transform digital files like graphic art, music, videos, etc. into digital assets. NFTs are often framed as a way for artists and other creators to profit from their activities, transforming ‘experiences’ into something for sale. As such, NFTs raise some questions pertinent to science and

Oil wastewater often contains high levels of radium, a carcinogenic and radioactive element. This article closely engages with two investigations of radium in groundwater downstream from oil wastewater storage pits. While one investigation found that radium did not travel beyond the storage pits, the other found evidence of elevated radium some two kilometers downstream. With an agential realist analysis

This article explores how science is mobilized as a collective identity, normative ideal, and instrumental tactic in contentious online global advocacy campaigns on the origins of the SARS-CoV-2 virus. It incorporates qualitative analysis of over 2300 public Twitter postings by core zoonosis and lab origin proponents who identify as scientists. These online exchanges provide a real-time window into

In March 2024, the Anthropocene Working Group’s proposal for a formal Anthropocene Series/Epoch of the Geologic Time Scale was formally rejected by the Subcommission on Quaternary Stratigraphy. What does the failed formalization effort reveal about the relationship between science and normativity under conditions of ‘climate crisis’? Drawing on four years of ethnographic observation of the Anthropocene

This article discusses examples from an extended family of aphorisms, stories, and themes that have circulated widely in STS and remain associated with the formation and integration of the field. Drawing upon Harvey Sacks’s insightful remarks about features of everyday conversation, which he related to ancient practices in oral culture, we argue that familiar citation magnets in STS operate in many

How have Western nongovernmental experts used remote sensing to make public knowledge about Iran’s nuclear program? This article recounts several episodes in which experts and journalists congregated around satellite images to uncover hidden nuclear objects in Iran. Drawing from the theoretical tradition of co-production, I describe this recurrent collective experience as an imaginative exercise that

Given the many forms of environmental pollution that have accompanied the global spread of industrial capitalism, there is an urgent need to carry out extensive assessments of the potential toxicity of many compounds on human and nonhuman populations. However, the scientific procedures developed to carry out such assessments present several critical shortcomings that greatly diminish their capacity

The literature engaging political theory in STS often puts forward a deficit model view of STS, in which homegrown STS ideas about politics, such as co-production, are either treated as having an insufficient account of the political or not read as political theory at all. This article challenges the deficit discourse by reading co-production as a full-blown political theory in its own right, in particular

Psychiatry has recently witnessed the launch of digital phenotyping as a new research agenda. According to digital phenotyping’s hypothesis, data about a patient’s daily behavior can be continuously collected through wearable monitoring devices and used to build software that would send warnings of mental relapse or would tailor treatment choices. The research is exploratory, and the claims upon which

The production of large, shareable datasets is increasingly prioritized for a wide range of research purposes. In biomedicine, especially in the United States, calls to enhance representation of historically underrepresented populations in databases that integrate genomic, health history, demographic and lifestyle data have also increased in order to support the goals of precision medicine. Understanding

The opaque relationship between biology and behavior is an intractable problem for psychiatry, and it increasingly challenges longstanding diagnostic categorizations. While various big data sciences have been repeatedly deployed as potential solutions, they have so far complicated more than they have managed to disentangle. Attending to categorical misalignment, this article proposes one reason why

The 2002 film Minority Report regularly appears in tech press articles asking whether it ‘predicted the future’. When such publications invoke the film as having ‘predicted the future’ or ‘come true’, what social and political claims are being made? How has Minority Report become a discursive tool for imagining, constructing, and criticizing sociotechnical worlds? In this paper, we evaluate the worldbuilding

Drawing on ethnographic fieldwork, this paper unfolds the past and present uses of pigs that structured the emergence of a pig model of gut-hormone based appetite control, leading to the current scientific breakthrough in treatment of obesity. While the hyping of next generation medications for obesity and type 2 diabetes centers on the efficacy and profits attached to these drugs, I unfold how science

This is a review essay based primarily on the 2021 Routledge Handbook of Art, Science, and Technology Studies, edited by Hannah Star Rogers, Megan K. Halpern, Dehlia Hannah, and Kathryn de Ridder-Vignone. It focuses particularly on the use of art for public engagement with science and technology and it also draws upon the following books: Dialogues Between Artistic Research and Science and Technology

When a technology is seen as the right solution to a recognized problem, the development of alternative technologies comes under threat. To secure much-needed resources, proponents of alternative technologies must, in these conditions, restart societal discussion on the status quo, a process at once technological and discursive known as ‘path creation’. In this article, we investigate discussion-restarting

There is a rich body of literature on numbers as tools of governance. But the attention of the corpus in question is almost entirely on the rational properties of quantification. This article shows that government by numbers is also, and inseparably, a government by feelings. The Covid-19 pandemic was also a datademic in the sense that numbers populated and spread through the public sphere. We focus

There are widespread calls for increased demographic diversity in science, often linked to the epistemic claim that including more perspectives will improve the quality of the knowledge produced. By distinguishing between demographic and epistemic diversity, we show that this is only true some of the time. There are cases where increasing demographic diversity will not bring about the necessary epistemic

STS theories of biocapital conceptualize how biomedical knowledge and capital form together. Though these formations of biocapital often are located in large urban centers, few scholars have attended to how they are transforming urban spaces and places. In this paper we argue that the twinned technological development of cells and cities concentrates economic and symbolic capital and sets in motion

Sociotechnical imaginaries (SIs) have emerged as a popular and generative concept within Science and Technology Studies (STS). This article draws out the affective component of SIs, combining a review of relevant literatures with an empirical case study of an anti-fracking imaginary in Ireland to suggest how we might theorize an affective technopolitics of SIs. The literature review identifies three

Chickens have become emblematic of the Anthropocene: They embody the age of acceleration, (post-) industrial value, and intensification in scientific and technological knowledge and practice. Contemporary chickens are the bearers of significant genetic and nutritional knowledge, experimented upon and 'tweaked' so much so that some have denied that contemporary commercial chickens are chickens at all

How do precision medicine initiatives (re)organize relations between individuals and populations? In this article, we investigate how the curation of national genomic populations enacts communities and, in so doing, constructs mutual obligation between individuals and the state. Drawing on ethnographic fieldwork in the Danish National Genome Center (DNGC), we show how members of advisory bodies negotiated

Biobanks are becoming ubiquitous infrastructures in zoology and other non-human life sciences. They promise to store frozen research samples for the long term for future use. That use remains speculative but nevertheless needs to be anticipated. Following the establishment of a physical and digital infrastructure for frozen samples in an animal biobanking project, this article explores how the future

Energy transitions are knowledge-intensive processes where a multitude of actors are trying to cope with inevitable knowledge gaps, surprises, and uncertainties. In this context, we focus on two techno-physical phenomena that are gaining practical relevance with the expansion of wind and geothermal energy extraction, and are surrounded by significant unknowns: wake effects and temperature plumes. Both

What is a diagnostic test for? We might assume the answer to this question is straightforward. A good test would help identify what disease someone suffers from, assist health providers to determine the correct course of treatment and/or enable public health authorities to know and intervene in health at the level of the population. In this article, we show that what a specific diagnostic test is for

This article examines the value of medical technology through the case of electroencephalograms (EEGs), devices used to visualize brain activity and diagnose seizures. Drawing on ethnographic fieldwork, the article shows that EEGs are valued differently by patients and medical practitioners. While practitioners value EEGs for their clinical utility, i.e., ability to inform clinical decisions, patients

Biodiversity is a multidimensional concept that can be understood and measured in many different ways. However, the next generation of digital technologies for biodiversity monitoring currently being funded and developed fail to engage its multidimensional and relational aspects. Based on empirical data from interviews, a conference visit, online meetings, webinars, and project reports, this study

The West Virginia University (WVU) Personal Rapid Transit (PRT) system was built between 1971 and 1975 in Morgantown, West Virginia to be a prototype transportation system of the future. Envisioned as a hybrid of public and automotive transportation, the fully automated cars deliver passengers directly to their destinations without stopping at intervening stations. The PRT concept may be familiar to

In recent years, concerns about a crisis of expert authority have been expressed across the globe. Japan is no exception to this trend. Scandals surrounding the (mis)management of the 2011 Fukushima Daiichi nuclear power plant disaster severely damaged public confidence in state institutions, posing an additional challenge for those engaged in radiological protection. This article examines how claims

What is the role of experts and their expertise in the context of trans-science, in which issues that are raised in scientific terms cannot be answered by science alone? This article examines the discourses and practices around safety of low-dose exposure to radiation in the ongoing aftermath of the Fukushima Daiichi Nuclear Power Plant accident in Japan in 2011. Following the nuclear fallout, scientific

A key ambition in care studies has been to study care in practice and as practice. By turning towards practices, care studies has rendered visible and acknowledged important work that is not captured through looking at formal procedures or official and written materials, such as policy documents and medical protocols. In this literature, document materials and the written have often been seen as unable

This article uses historical and ethnographic methods to examine the primarily East-Central European Interoceanmetal Joint Organization (IOM). I ask how and why the IOM has survived as an institution since its inception in 1987, working especially with the personal archive of Vratislav Kubišta. Kubišta was a metallurgist and former Deputy Director General at IOM who after retirement sought to develop

In this article I follow the mystery of millions of tons of materials washed out to sea by the March 2011 Japan tsunami: a massive wave of lost materials expected to reach North American shores that never seems to officially arrive. I bring Gordon’s conceptualization of haunting together with STS conversations about absence and invisibility to build on feminist approaches that do not take as given

This article analyses attempts to enact complexity in postgenomic experimentations using the case of epigenetic research on biomarkers of psychosocial stress. Enacting complexity in this research means dissecting multiple so-called biosocial processes of health differentiation in the face of stressful experiences. To characterize enactments of biosocial complexity, the article develops the concepts

This article analyses the transformation of information security induced by the Jericho Forum, a group of security professionals who argued for a new 'de-perimeterised' security model. Having focused on defensive perimeters around networks, early 2000s information security faced a growing set of pressures: the maintainability of firewalls given increasing traffic volume and variety, the vulnerability

Embodied health movements (EHMs) advance their agendas by mediating the production, circulation, and revision of biomedical knowledge. To do this, their constituents become lay experts by blending their embodied experience of illness with self-taught technical knowledge. However, it is unclear how lay expertise is routinized within EHMs, and consequently, to what extent it can be made durable in long-term

How can we trace differing normative values, and especially in alternative imaginaries of environmentally sustainable futures? To address this issue, this article extends the sociotechnical imaginaries framework by providing conceptual tools to understand the underlying rationale of alternative environmental imaginaries-through an envirotechnical analysis. I analyse an urban river restoration project

If an apparently extinct bird calls in a forest, and there are people there to hear it-to record it, even-is it still extinct? The Ivory-billed Woodpecker was last 'officially' seen in the United States in 1944, but its extinction continues to be a subject of intense debate between conservation authorities, scientists, and grassroots activists. Tensions peaked around 2005, when scientists from the

Health policies and the problems they constitute are deeply shaped by multiple publics. In this article we conceptualize health policy counterpublics: temporally bounded socio-political forms that aim to cultivate particular modes of conduct, generally to resist trajectories set by arms of the state. These counterpublics often emerge from existing social movements and involve varied forms of activism

This article explores how innovation logics infiltrate problem and value definitions in maintenance and repair, and how innovation itself depends on considerable, often invisible care work beyond the seemingly smooth entrepreneurial narratives. We build on a growing body of work in STS that investigates the relationship between innovation and maintenance and repair. This literature argues that the

Data are versatile objects that can travel across contexts. While data's travels have been widely discussed, little attention has been paid to the sites from where and to which data flow. Drawing upon ethnographic fieldwork in two connected data-intensive laboratories and the concept of domestication, we explore what it takes to bring data 'home' into the laboratory. As data come and dwell in the home

This special issue interrogates race through the lens of face. Its central faces are those in forensic settings. Promising immediate legibility and access to the individual suspect, forensic faces nevertheless mobilize a variety of collectives. We offer conceptual and methodological tools to examine the face as both an individual and a collective phenomenon, and demonstrate through detailed cases how

This article analyses how a recent idiom of innovation governance, 'responsible innovation', is enacted in practice, how this shapes innovation processes, and what aspects of innovation are left untouched. Within this idiom, funders typically focus on one point in an innovation system: researchers in projects. However, the more transformational aspirations of responsible innovation are circumscribed

What is race? And how does it figure in different scientific practices? To answer these questions, I suggest that we need to know race differently. Rather than defining race or looking for one conclusive answer to what it is, I propose methods that are open-ended, that allow us to follow race around, while remaining curious as to what it is. I suggest that we pursue generous methods. Drawing on empirical

Certain fields of research are deeply shaped by their proximity with policy-makers and administrations. The so-called 'regulatory sciences' and their corresponding expert communities emerge from this intermediary space between science and policy. Social studies of expertise and scientific experts show, however, that modes of engagement with policy-making vary greatly from one scientist to another.

In the early 2010s, a spectacular fall in prices for a class of mineral commodities called the rare earth elements (REEs) and the collapse of hundreds of new exploration companies made clear the fragility of the high-risk markets around these companies and the strategies of legitimation that supported them. New regulatory processes built around technical disclosures generated vast stores of geotechnical

What makes one dataset powerful for civic advocacy, and another fall flat? Drawing from a citizen science project on environmental health, I argue that there is an underacknowledged quality of datasets-their topology-that shapes the social, cultural, and political possibilities they can sustain or subvert. Data topologies are formal qualities of a dataset that connect data collectors' intentions with

Mathematics is often treated as different from other disciplines, since arguments in the field rely on deductive proof rather than empirical evidence as in the natural sciences. A mathematical paper can therefore, at least in principle, be replicated simply by reading it. While this distinction is sometimes taken as the basis to claim that the results in mathematics are therefore certain, mathematicians

Immunotherapy is heralded as the 'fifth pillar' of cancer therapy, after surgery, radiotherapy, chemotherapy and genomic medicine. It involves 'harnessing' patients' own immune system T-cells to treat cancer. In this article, I draw on qualitative interviews with practitioners working in oncology and patients in the UK, to trace metaphorical and discursive framing around immunotherapy. Immunotherapy

Stakeholder engagement has become a watchword for environmental scientists to assert the societal relevance of their projects to funding agencies. In water research based on computer simulation modelling, stakeholder engagement has attracted interest as a means to overcome low uptake of new tools for water management. An increasingly accepted view is that more and better stakeholder involvement in

For decades, playing Go at a professional level has counted among those things that, in Dreyfus's words, 'computers still can't do'. This changed dramatically in early March 2016, at the Four Seasons Hotel in Seoul, South Korea, when AlphaGo, the most sophisticated Go program at the time, beat Lee Sedol, an internationally top-ranked Go professional, by four games to one. A documentary movie has captured

How can we examine so-called 'artificial intelligence' ('AI') without turning our backs on the STS tradition that questions both notions of artificiality and intelligence? This special issue attempts a step to the side: Instead of considering 'AI' as something that does or does not exist (and then taking a position on its benefits or harms), its ambition is to document, in an empirical and agnostic

This article expands on recent studies of machine learning or artificial intelligence (AI) algorithms that crucially depend on benchmark datasets, often called 'ground truths.' These ground-truth datasets gather input-data and output-targets, thereby establishing what can be retrieved computationally and evaluated statistically. I explore the case of the Tumor nEoantigen SeLection Alliance (TESLA)

The article explores technology-human relations in a time of artificial intelligence (AI) and in the context of long-standing problems in social theory about agency, nonhumans, and autonomy. Most theorizations of AI are grounded in dualistic thinking and traditional views of technology, oversimplifying real-world settings. This article works to unfold modes of existence at play in AI/human relations

Scheduled meetings are associated with standardization and understood as a bureaucratic form of coordination, control, and rule observation. In attending assemblies of a research team in optical physics for over a year, we found regular lab meetings are compulsory for all their members and are an avenue to announce and give information about new and changed institutional regulations, to supervise members'

What happens when an algorithm is added to the work of an expert group? This study explores how algorithms pose a practical problem for experts. We study the introduction of a Probabilistic DNA Profiling (PDP) software into a forensics lab through interviews and court admissibility hearings. While meant to support experts' decision-making, in practice it has destabilized their authority. They respond

Calling attention to the growing intersection between the insurance and technology sectors-or 'insurtech'-this article is intended as a bat signal for the interdisciplinary fields that have spent recent decades studying the explosion of digitization, datafication, smartification, automation, and so on. Many of the dynamics that attract people to researching technology are exemplified, often in exaggerated

This paper investigates the role of the materiality of computation in two domains: blockchain technologies and artificial intelligence (AI). Although historically designed as parallel computing accelerators for image rendering and videogames, graphics processing units (GPUs) have been instrumental in the explosion of both cryptoasset mining and machine learning models. The political economy associated