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Elevated EBF2 in mouse but not pig drives the progressive brown fat lineage specification via chromatin activation J. Adv. Res. (IF 11.4) Pub Date : 2024-12-28 Yinlong Liao, Zhelun Peng, Shanshan Fu, Yao Hua, Wenzhe Luo, Ruige Liu, Yingjin Chen, Wei Gu, Pengxiang Zhao, Jianguo Zhao, Yanfang Wang, Heng Wang
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D-Mannose-Mediated metabolic pathways sustain the molecular signatures of sperm function and fertilization J. Adv. Res. (IF 11.4) Pub Date : 2024-12-27 Wenlong Zhao, Nihao Gu, Xueyuan Liu, Ningxin Qing, Jianzhong Sheng, Xianhua Lin, Hefeng Huang
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Comprehensive analysis of heterogeneity and cell-cell interactions in Crohn’s disease reveals novel location-specific insights J. Adv. Res. (IF 11.4) Pub Date : 2024-12-26 Jing Feng, Li-Na He, Ruchen Yao, Yuqi Qiao, Tian Yang, Zhe Cui, Xiangjun Meng, Jinlu Tong, Keyu Jia, Zhixiang Zuo, Jun Shen
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Protein palmitoylation in hepatic diseases: Functional insights and therapeutic strategies J. Adv. Res. (IF 11.4) Pub Date : 2024-12-26 Ying Wang, Haoyuan Ma, Bowen Zhang, Sainan Li, Beijia Lu, Yingcheng Qi, Tingting Liu, Hua Wang, Xiaohong Kang, Yinming Liang, Eryan Kong, Liu Cao, Binhui Zhou
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Lonicera caerulea genome reveals molecular mechanisms of freezing tolerance and anthocyanin biosynthesis J. Adv. Res. (IF 11.4) Pub Date : 2024-12-26 Jing Wang, Xiaotong Wang, Yuwei Ma, Ranran Gao, Yongmiao Wang, Zhoujie An, Ya Tian, Huihua Wan, Dianwen Wei, Feng Wang, Baojiang Zheng, Baozhong Duan, Li Xiang, Gangqiang Dong, Wei Sun, Zhichao Xu
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Risk classification for non-cancer death in middle-aged cancer patients J. Adv. Res. (IF 11.4) Pub Date : 2024-12-25 Tianwang Guan, Yanting Jiang, Peinan Tu, Baokui Ye, Liangjia Zeng, Zehao Luo, Kaiyi Chi, Haowen Liang, Yuting Yang, Jinqi Huang, Binghua Zhang, Rundong Tai, Jujian Ye, Zhilin Deng, Yushen Ke, Huiwan Chen, Zhiling Zhang, Zhigang Liu, Caiwen Ou
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Evaluating current status of network pharmacology for herbal medicine focusing on identifying mechanisms and therapeutic effects J. Adv. Res. (IF 11.4) Pub Date : 2024-12-25 Won-Yung Lee, Kwang-Il Park, Seon-Been Bak, Seungho Lee, Su-Jin Bae, Min-Jin Kim, Sun-Dong Park, Choon Ok Kim, Ji-Hwan Kim, Young Woo Kim, Chang-Eop Kim
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Non-destructive detection strategy of maize seed vigor based on seed phenotyping and the potential for accelerating breeding J. Adv. Res. (IF 11.4) Pub Date : 2024-12-25 Keling Tu, Shaozhe Wen, Yanan Xu, Hongju He, He Li, Rugen Xu, Baojian Guo, Chengming Sun, Riliang Gu, Qun Sun
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Targeting APJ drives BNIP3-PINK1-PARKIN induced mitophagy and improves systemic inflammatory bone loss J. Adv. Res. (IF 11.4) Pub Date : 2024-12-25 Wentao Wang, Qing Wang, Wenming Li, Hao Xu, Xiaolong Liang, Wei Wang, Ning Li, Huilin Yang, Yaozeng Xu, Jiaxiang Bai, Shuli Yang, Dechun Geng
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Loss of glomerular aldolase B in diabetic nephropathy promotes renal fibrosis via activating Akt/GSK/β-catenin axis J. Adv. Res. (IF 11.4) Pub Date : 2024-12-24 Minghui Liu, Wenwen Yang, Shuang Qu, Tingting Zhao, Song Jiang, Suming Peng, Mingchao Zhang, Ji Xuan, Zhihong Liu, Ke Zen
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Adiponectin deficiency prevents chronic colitis-associated colonic fibrosis via inhibiting CXCL13 production J. Adv. Res. (IF 11.4) Pub Date : 2024-12-24 Haitao Xiao, Tianhang Xing, Miao Qiu, Guangtao Zhang, Gongli Yang, Wenke Chen, Die Hu, Deao Xue, Jiao Peng, Bin Du
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Design of highly leaf-adhesive and anti-UV herbicide nanoformulation for enhanced herbicidal activity J. Adv. Res. (IF 11.4) Pub Date : 2024-12-22 Dongdong Li, Jianan Li, Hao Li, Zhendong Bai, Chujian Ma, Haodong Bai, Dingfeng Luo, Zuren Li, Lianyang Bai
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Absence of gut microbiota alleviates iron overload-induced colitis by modulating ferroptosis in mice J. Adv. Res. (IF 11.4) Pub Date : 2024-12-20 Ke Gu, Aimin Wu, Chen Liu, Bing Yu, Jun He, Xin Lai, Junzhou Chen, Yuheng Luo, Hui Yan, Ping Zheng, Junqiu Luo, Junning Pu, Quyuan Wang, Huifen Wang, Daiwen Chen
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The role of cGAS-STING signaling pathway in ferroptosis J. Adv. Res. (IF 11.4) Pub Date : 2024-12-20 Lina Ding, Ruicheng Zhang, Wenqi Du, Qingling Wang, Dongsheng Pei
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The role of trehalose metabolism in plant stress tolerance J. Adv. Res. (IF 11.4) Pub Date : 2024-12-19 Tong-Ju Eh, Yaxuan Jiang, Mingquan Jiang, Jianxin Li, Pei Lei, Ximei Ji, Hyon-Il Kim, Xiyang Zhao, Fanjuan Meng
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Maternal fish oil supplementation enhances placental nutrient transport and mammary gland secretion via the GPR120 signaling pathway J. Adv. Res. (IF 11.4) Pub Date : 2024-12-19 Qihui Li, Qianzi Zhang, Senlin Su, Siwang Yang, Jiayuan Shao, Wutai Guan, Shihai Zhang
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Targeting ATM enhances radiation sensitivity of colorectal cancer by Potentiating radiation-induced cell death and antitumor immunity J. Adv. Res. (IF 11.4) Pub Date : 2024-12-19 Yuwen Xie, Yang Liu, Mingdao Lin, Zhenkang Li, Zhiyong Shen, Shengqi Yin, Yilin Zheng, Yishu Zou, Yaowei Zhang, Yizhi Zhan, Yuan Fang, Yi Ding
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Biomechanical research using advanced micro-nano devices: In-Vitro cell Characterization focus J. Adv. Res. (IF 11.4) Pub Date : 2024-12-17 Shiqiang Yan, Yan Lu, Changming An, Wanglai Hu, Yaofeng Chen, Ziwen Li, Wenbo Wei, Zongzheng Chen, Xianhai Zeng, Wei Xu, Zhenghua Lv, Fan Pan, Wei Gao, Yongyan Wu
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An AP2/ERF transcription factor controls generation of the twin-seedling rice J. Adv. Res. (IF 11.4) Pub Date : 2024-12-17 Kaichong Teng, Neng Zhao, Yonghong Xie, Rongbai Li, Jianxiong Li
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FTO activates PD-L1 promotes immunosuppression in breast cancer via the m6A/YTHDF3/PDK1 axis under hypoxic conditions J. Adv. Res. (IF 11.4) Pub Date : 2024-12-17 Siyu Wang, Xingda Zhang, Quanrun Chen, Hao Wu, Shihan Cao, Shilu Zhao, Guozheng Li, Jianyu Wang, Yajie Gong, Xinheng Wang, Da Pang, Song Gao
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Exploring the mediating roles of depression and cognitive function in the association between sarcopenia and frailty: A Cox survival analysis approach J. Adv. Res. (IF 11.4) Pub Date : 2024-12-17 Yan Zhu, Haojie Yin, Xianli Zhong, Qin Zhang, Li Wang, Rong Lu, Ping Jia
Despite earlier research indicating a potential link between the development of sarcopenia and an elevated risk of frailty, the lack of comprehensive prospective data on the correlation between sarcopenia and frailty incidence leaves open the question of whether depression and cognitive function mediate this association.
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Selective Regulation of ray tissue for achieving ultrastable Zero-Poisson’s-ratio material out of wood J. Adv. Res. (IF 11.4) Pub Date : 2024-12-15 Xia Yu, Xinyi Zhou, Tong Wu, Bohua Ren, Tao Fang, Chaonan Cong, Guofang Wu, Lihong Yao, Xiaoding Wei, Bo Liu, Yun Lu
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Advances in statin adverse reactions and the potential mechanisms: A systematic review J. Adv. Res. (IF 11.4) Pub Date : 2024-12-14 Weiwei Zeng, Huan Deng, Yuning Luo, Shilong Zhong, Min Huang, Brian Tomlinson
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Insulin-like growth factor binding protein 7 identified in aged dental pulp by single-cell RNA sequencing J. Adv. Res. (IF 11.4) Pub Date : 2024-12-12 Zhongchun Tong, Jie Wu, Qimei Gong, Yifang Yuan, Shengchao Wang, Wenkai Jiang
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Natural small molecule hinokitone mitigates NASH fibrosis by targeting regulation of FXR-mediated hepatocyte apoptosis J. Adv. Res. (IF 11.4) Pub Date : 2024-12-13 Ze-Jiang Ma, Ying-Kun Qiu, Zhe-Wei Yu, Tian-Tian Song, Yi-Tong Hu, An-Kang Peng, Rong Qi
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Improving grain yield and salt tolerance by optimizing plant height with beneficial haplotypes in rice (Oryza sativa) J. Adv. Res. (IF 11.4) Pub Date : 2024-12-12 Ruidang Quan, Juan Wang, Hua Qin, Liang Chen, Dinglin Xiao, Zihan Zhao, Zhanying Zhang, Xiaoyang Zhu, Zichao Li, Rongfeng Huang
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Soybean nodulation shapes the rhizosphere microbiome to increase rapeseed yield J. Adv. Res. (IF 11.4) Pub Date : 2024-12-12 Yu Liu, Qin Han, Jiaming Zhang, Xuehai Zhang, Yuqin Chen, Mingbo Li, Yongfang Hao, Yujie Hong, Ruizhen Tang, Brett J. Ferguson, Peter M. Gresshoff, Jie Kuai, Guangsheng Zhou, Xia Li, Hongtao Ji
Crop rotation, a crucial agricultural practice that enhances soil health and crop productivity, is widely used in agriculture worldwide. Soybeans play a crucial role in crop rotation owing to their nitrogen-fixing ability, which is facilitated by symbiotic bacteria in their root systems. The soybean-rapeseed rotation is an effective agricultural practice in the Yangtze River Basin of China. However
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CD34+CLDN5+ tumor associated senescent endothelial cells through IGF2-IGF2R signaling increased cholangiocellular phenotype in hepatocellular carcinoma J. Adv. Res. (IF 11.4) Pub Date : 2024-12-12 Xin-yu Zhu, Wen-ting Liu, Xiao-juan Hou, Chen Zong, Wei Yu, Zhe-min Shen, Shu-ping Qu, Min Tao, Meng-meng Xue, Dao-yu Zhou, Hao-ran Bai, Lu Gao, Jing-hua Jiang, Qiu-dong Zhao, Li-xin Wei, Xue Yang, Zhi-peng Han, Li Zhang
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Predictive value of remnant cholesterol inflammatory index for stroke risk: Evidence from the China health and Retirement Longitudinal study J. Adv. Res. (IF 11.4) Pub Date : 2024-12-12 Jiaying Chen, Qiheng Wu, Haotian Liu, Weike Hu, JiaJia Zhu, Zhong Ji, Jia Yin
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Bio-friendly multi-stimuli responsive α-CD polymer-gated mesoporous carbon nanoherbicides for enhanced paraquat delivery J. Adv. Res. (IF 11.4) Pub Date : 2024-12-12 Jiangtao Dong, Guoquan Wang, Xiaona Li, Aohui Han, Wanpeng Zhang, Yuhang Yue, Yue Yang, Yishan Wang, Bowen Yuan, Jiahui Wang, Yuhui Peng, Runqiang Liu, Si Chen, Xuezhong Du
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Macrophage P2Y12 regulates iron transport and its inhibition protects against atherosclerosis J. Adv. Res. (IF 11.4) Pub Date : 2024-12-12 Yang-Xi Hu, Hong-Min You, Mei-Rong Bai, Wen-Heng Yue, Fang-Fang Li, Bo-Wen Hu, Ya-Sha Chen, Xiang-Yu Shen, Yue Wu, Jia-Mei Wang, Zhi-Qing He, Xia Tao, Qing Jing, Chun Liang
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KBTBD8/RRP15 as a potential novel therapeutic target associates with lenvatinib-inhibited progression in hepatocellular carcinoma both in vitro and in vivo J. Adv. Res. (IF 11.4) Pub Date : 2024-12-11 Saili Zhao, Xuran Wang, Rui Wu, Fenglan Wang, Xiaoxuan Tang, Junhui Chen, Runqiu Jiang, Wei Kang, Guifang Xu, Lei Wang, Zhangding Wang, Xiaoping Zou, Bin Zhang
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Genome-wide profiling and functional study of short N-terminal H2B variants in Arabidopsis J. Adv. Res. (IF 11.4) Pub Date : 2024-12-11 Peng Yao, Qin He, Ying Wang, Danyang Sun, Xiangsong Chen, Li Lu
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Dissecting the anti-obesity components of ginseng: How ginseng polysaccharides and ginsenosides target gut microbiota to suppress high-fat diet-induced obesity J. Adv. Res. (IF 11.4) Pub Date : 2024-12-11 Han-Yan Luo, Jing Fang, Wei-Hao Zhang, Kam-Chun Chan, Yui-Man Chan, Cai-Xia Dong, Song-Lin Li, Ai-Ping Lyu, Jun Xu
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Key β1-4 galactosylated glycan receptors of SARS-CoV-2 and its inhibitor from the galactosylated glycoproteins of bovine milk J. Adv. Res. (IF 11.4) Pub Date : 2024-12-10 Hanjie Yu, Wentian Chen, Jian Shu, Xin Wu, Jia Quan, Hongwei Cheng, Xiaojuan Bao, Di Wu, Xilong Wang, Zheng Li
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ORP5 promotes cardiac hypertrophy by regulating the activation of mTORC1 on lysosome J. Adv. Res. (IF 11.4) Pub Date : 2024-12-10 Di Zhao, Ran Xu, Yufei Zhou, Jiaying Wu, Xiaoxue Zhang, Hong Lin, Jienan Wang, Zhiwen Ding, Yunzeng Zou
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Not only the top: Type I topoisomerases function in multiple tissues and organs development in plants J. Adv. Res. (IF 11.4) Pub Date : 2024-12-09 Hao Zhang, Lirong Tian, Yuru Ma, Jiahui Xu, Tianyu Bai, Qian Wang, Xigang Liu, Lin Guo
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Dual regulation of phaseol on osteoclast formation and osteoblast differentiation by targeting TAK1 kinase for osteoporosis treatment J. Adv. Res. (IF 11.4) Pub Date : 2024-12-09 Lihua Tan, Zhimin Miao, Yuxin Zhao, Yongkai Liang, Nan Xu, Xin Chen, Yanbei Tu, Chengwei He
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Ubiquitin proteasome system in cardiac fibrosis J. Adv. Res. (IF 11.4) Pub Date : 2024-12-07 Linqi Zeng, Xiaokai Zhang, Zihang Huang, Shuai Song, Mohan Li, Tongyao Wang, Aijun Sun, Junbo Ge
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Cancer-associated fibroblasts regulate mitochondrial metabolism and inhibit chemosensitivity via ANGPTL4-IQGAP1 axis in prostate cancer J. Adv. Res. (IF 11.4) Pub Date : 2024-12-06 Zhi Xiong, Rui-Lin Zhuang, Shun-Li Yu, Zhao-Xiang Xie, Shi-Rong Peng, Ze-An Li, Bing-Heng Li, Jun-Jia Xie, Yi-Ning Li, Kai-Wen Li, Hai Huang
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Asperosaponin VI inhibition of DNMT alleviates GPX4 suppression-mediated osteoblast ferroptosis and diabetic osteoporosis J. Adv. Res. (IF 11.4) Pub Date : 2024-12-06 Fanhao Wei, Binjia Ruan, Jian Dong, Bin Yang, Guofu Zhang, Wai Kwok Kelvin Yeung, Hongwei Wang, Wangsen Cao, Yongxiang Wang
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Unlocking biological insights from differentially expressed genes: Concepts, methods, and future perspectives J. Adv. Res. (IF 11.4) Pub Date : 2024-12-06 Huachun Yin, Hongrui Duo, Song Li, Dan Qin, Lingling Xie, Yingxue Xiao, Jing Sun, Jingxin Tao, Xiaoxi Zhang, Yinghong Li, Yue Zou, Qingxia Yang, Xian Yang, Youjin Hao, Bo Li
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Hypo-osmolarity promotes naive pluripotency by reshaping cytoskeleton and increasing chromatin accessibility J. Adv. Res. (IF 11.4) Pub Date : 2024-12-04 Renhong Lu, Bowen Lin, Zheyi Lin, Hui Xiong, Junyang Liu, Li Li, Zheng Gong, Siyu Wang, Mingshuai Zhang, Jie Ding, Chengwen Hang, Huixin Guo, Duanyang Xie, Yi Liu, Dan Shi, Dandan Liang, Zhen Liu, Jian Yang, Yi-Han Chen
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Targeting Dlat-Trpv3 pathway by hyperforin elicits non-canonical promotion of adipose thermogenesis as an effective anti-obesity strategy J. Adv. Res. (IF 11.4) Pub Date : 2024-12-02 Sijia Lu, Quanxin Jiang, Peihui Zhou, Limin Yin, Ning Wang, Junting Xu, Qiqi Qian, Mijia Tao, Hanrui Yin, Liu Han, Yunqing Gu, Fei Gao, Junli Liu, Suzhen Chen
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The potential of circular RNAs as biomarkers and therapeutic targets for gastric cancer: A comprehensive review J. Adv. Res. (IF 11.4) Pub Date : 2024-11-29 Junlin Pu, Xiuli Yan, Hui Zhang
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Full dimensional dynamic 3D convolution and point cloud in pulmonary nodule detection J. Adv. Res. (IF 11.4) Pub Date : 2024-11-29 Yun Tie, Ying Wang, Dalong Zhang, Zepeng Zhang, Fenghui Liu, Lin Qi
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Exercise-regulated lipolysis: Its role and mechanism in health and diseases J. Adv. Res. (IF 11.4) Pub Date : 2024-11-28 Jie-Ying Zhu, Liang Guo
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Fungus-derived opine enhances plant photosynthesis J. Adv. Res. (IF 11.4) Pub Date : 2024-11-25 Dekun Kong, Li Cui, Xiaozheng Wang, Jing Wo, Fangjie Xiong
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Manipulation of artificial light environment improves plant biomass and fruit nutritional quality in tomato J. Adv. Res. (IF 11.4) Pub Date : 2024-11-24 Ying Zhang, Kangyou Zhu, Xiujie Wang, Jiarong Yan, Haiyan Zhu, Nan Zhang, Yiting Wang, Qi Zhao, Yanan Liu, Xin Bu, Chenghao Jiang, Xin Sun, Golam Jalal Ahammed, Shuyu Cai, Sida Meng, Zhouping Sun, Mingfang Qi, Tianlai Li, Feng Wang
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Trends, clinicopathological features, surgical treatment patterns and prognoses of early-onset versus late-onset gastric cancer: A retrospective cohort study J. Adv. Res. (IF 11.4) Pub Date : 2024-11-24 Yingxue Liu, Xiaoyan Zhang, Lu Gan, Zhikai Chen, Xin Wang, Jiayu Zhang, Jie Chen, Cong Tan, Weiqi Sheng, Midie Xu
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miR-3606-3p alleviates skin fibrosis by integratively suppressing the integrin/FAK, p-AKT/p-ERK, and TGF-β signaling cascades J. Adv. Res. (IF 11.4) Pub Date : 2024-11-20 Yahui Chen, Yiyi Gong, Mengkun Shi, Haoxing Zhu, Yulong Tang, Delin Huang, Wei Wang, Chenyi Shi, Xueyi Xia, Ying Zhang, Jianlan Liu, Jia Huang, Mengguo Liu, Huyan Chen, Yanyun Ma, Ziyu Wang, Lei Wang, Wenzhen Tu, Yinhuan Zhao, Jinran Lin, Li Jin, Jörg HW Distler, Wenyu Wu, Jiucun Wang, Xiangguang Shi
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Interleukin-10 deficiency suppresses colorectal cancer metastasis by enriching gut Parabacteroides distasonis J. Adv. Res. (IF 11.4) Pub Date : 2024-11-19 Jing Yu, Lili Feng, Zhanhao Luo, Jingyi Yang, Qiang Zhang, Chen Liu, Dayi Liang, Yanchun Xie, Hongmin Li, Junli Gong, Zhen He, Ping Lan
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An accurate prediction for respiratory diseases using deep learning on bronchoscopy diagnosis images J. Adv. Res. (IF 11.4) Pub Date : 2024-11-19 Weiling Sun, Pengfei Yan, Minglei Li, Xiang Li, Yuchen Jiang, Hao Luo, Yanbin Zhao
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Bacteroides uniformis ameliorates pro-inflammatory diet-exacerbated colitis by targeting endoplasmic reticulum stress-mediated ferroptosis J. Adv. Res. (IF 11.4) Pub Date : 2024-11-19 Caiguang Liu, Linxin Liu, Zhenyi Tian, Shukai Zhan, Yun Qiu, Manying Li, Tong Li, Ren Mao, Shenghong Zhang, Minhu Chen, Zhirong Zeng, Xiaojun Zhuang
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Self-adhesion conductive cardiac patch based on methoxytriethylene glycol-functionalized graphene effectively improves cardiac function after myocardial infarction J. Adv. Res. (IF 11.4) Pub Date : 2024-11-19 Xu Wang, Hao Wang, Xin Liu, Yuan Zhang, Jiamin Li, Heng Liu, Jing Feng, Wenqian Jiang, Ling Liu, Yongchao Chen, Xiaohan Li, Limin Zhao, Jing Guan, Yong Zhang
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Transient receptor potential channels in viral infectious diseases: Biological characteristics and regulatory mechanisms J. Adv. Res. (IF 11.4) Pub Date : 2024-11-17 Wen-Hui Qi, Na Tang, Zhi-Jing Zhao, Xiao-Qiang Li
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Kaempferol regulating macrophage foaming and atherosclerosis through Piezo1-mediated MAPK/NF-κB and Nrf2/HO-1 signaling pathway J. Adv. Res. (IF 11.4) Pub Date : 2024-11-17 Tianjiao Chu, Yuman Wang, Shihao Wang, Jinze Li, Zheng Li, Zihao Wei, Jing Li, Yifei Bian
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Generalized deep learning for histopathology image classification using supervised contrastive learning J. Adv. Res. (IF 11.4) Pub Date : 2024-11-16 Md Mamunur Rahaman, Ewan K.A. Millar, Erik Meijering