The gastrointestinal tract is continuously exposed to foreign antigens in food and commensal microbes with potential to induce adaptive immune responses. Peripherally induced T regulatory (pTreg) cells are essential for mitigating inflammatory responses to these agents1–4. While RORγt+ antigen-presenting cells (RORγt-APCs) were shown to program gut microbiota-specific pTreg5–7, their definition remains

Intersectionality describes interdependent systems of inequality related to sex, gender, race, age, class and other socio-political dimensions. By focusing on the compounded effects of social categories, intersectional analysis can enhance the accuracy and experimental efficiency of science. Here we extend intersectional approaches that were predominantly developed in the humanities, social sciences

A critical challenge in the commercialization of perovskite solar cells (PSCs) is the simultaneous attainment of high power conversion efficiency (PCE) and high stability. Employing polymers interfaces in PSCs can enhance durability by blocking water and oxygen, and by suppressing ions interdiffusion, but their electronic shielding poses a challenge for efficient and stable PSCs1–3. In this study,

Pyrazoles are heterocycles commonly found as key substructures in agrochemicals and medicinally active compounds alike.1,2 Despite their pervasiveness, established methods fall notably short in delivering complex pyrazoles selectively due to issues of differentiation during either assembly or N-functionalization.3 This is a direct consequence of a dominant synthetic strategy that attempts to control

The fractional quantum anomalous Hall (FQAH) effect was recently discovered in twisted MoTe2 bilayers (tMoTe2)1–4. Experiments to date have revealed Chern insulators from hole doping at ν = -1, -2/3, -3/5, and -4/7 (per moiré unit cell) 1–6. In parallel, theories predict that, between v = -1 and -3, there exist exotic quantum phases 7–15, such as the coveted fractional topological insulators (FTI)