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Distance Covariance, Independence, and Pairwise Differences Am. Stat. (IF 1.8) Pub Date : 2024-07-03 Jakob Raymaekers, Peter J. Rousseeuw
Distance covariance (Székely et al. 2007) is a fascinating recent notion, which is popular as a test for dependence of any type between random variables X and Y. This approach deserves to be touche...
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Targeting MAD2B as a strategy for ischemic stroke therapy J. Adv. Res. (IF 11.4) Pub Date : 2024-07-05 Lijing Zhang, Hengzhen Cui, Wandi Hu, Xianfang Meng, Chun Zhang
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Regenerative endodontic therapy: From laboratory bench to clinical practice J. Adv. Res. (IF 11.4) Pub Date : 2024-07-03 Xin Shi, Xiaohan Hu, Nan Jiang, Jing Mao
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Ginsenoside Rh4 inhibits colorectal cancer via the modulation of gut microbiota-mediated bile acid metabolism J. Adv. Res. (IF 11.4) Pub Date : 2024-07-03 Xue Bai, Zhiguang Duan, Jianjun Deng, Zhuo Zhang, Rongzhan Fu, Chenhui Zhu, Daidi Fan
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RNA modification gene WDR4 facilitates tumor progression and immunotherapy resistance in breast cancer J. Adv. Res. (IF 11.4) Pub Date : 2024-07-02 Yongzhou Luo, Wenwen Tian, Da Kang, Linyu Wu, Hailin Tang, Sifen Wang, Chao Zhang, Yi Xie, Yue Zhang, Jindong Xie, Xinpei Deng, Hao Zou, Hao Wu, Huan Lin, Weidong Wei
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E3 ubiquitin ligase RNF128 attenuates colitis and colorectal tumorigenesis by triggering the degradation of IL-6 receptors J. Adv. Res. (IF 11.4) Pub Date : 2024-07-02 Tian-Sheng He, Kuntai Cai, Weiling Lai, Jingge Yu, Furong Qing, Ao Shen, Lina Sui, Wenji He, Weihua Wang, Qiuxiang Xiao, Xiong Lei, Tianfu Guo, Zhiping Liu
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Macrophage exosomes mediate palmitic acid-induced metainflammation by transferring miR-3064-5p to target IκBα and activate NF-κB signaling J. Adv. Res. (IF 11.4) Pub Date : 2024-07-02 Huiyu Luo, Jiexian Wang, Fengjuan Lin, Yuguo Liu, Xinglong Wu, Gan Li, Chuhong Su, Junbin Chen, Fei Xiong, Jiaqi Mo, Zhongdaixi Zheng, Xiangyi Zheng, Qing Li, Longying Zha
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The role of SPI1/VSIG4/THBS1 on glioblastoma progression through modulation of the PI3K/AKT pathway J. Adv. Res. (IF 11.4) Pub Date : 2024-07-01 Jie Shen, Lihui Zhou, Ke Ye, Jiangbiao Gong, Fan Wu, Kangnan Mo, Yu Zhu, Chao Chen, Renya Zhan
Glioblastoma multiforme (GBM) poses a significant challenge in terms of treatment due to its high malignancy, necessitating the identification of additional molecular targets. VSIG4, an oncogenic gene participates in tumor growth and migration in various cancer types. Nevertheless, the precise process through which VSIG4 facilitates the malignant progression of glioma remains to be elucidated. This
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A Multi-Method Data Science Pipeline for Analyzing Police Service Am. Stat. (IF 1.8) Pub Date : 2024-07-01 Anna Haensch, Daanika Gordon, Karin Knudson, Justina Cheng
Despite the fact that most police departments in the U.S. serve jurisdictions with fewer than 10,000 residents, policing practices in small towns are understudied. This is due in part to data limit...
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The mechanism by which oriented polypropylene packaging alleviates postharvest ‘Black Spot’ in radish root (Raphanus sativus) J. Adv. Res. (IF 11.4) Pub Date : 2024-06-28 Zixin Lin, Bihong Feng, Shibei Fang, Xi Pang, Huafeng Liang, Shuzhi Yuan, Xiaodi Xu, Jinhua Zuo, Xiaozhen Yue, Qing Wang
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WTAP/YTHDF1-mediated m6A modification amplifies IFN-γ-induced immunosuppressive properties of human MSCs J. Adv. Res. (IF 11.4) Pub Date : 2024-06-27 Quan Chen, Luoquan Ao, Qing Zhao, Lu Tang, Yanli Xiong, Yuchuan Yuan, Xiaofeng Wu, Wei Xing, Zhan Li, Wei Guo, Huaping Liang, Song Guo Zheng, Qizhou Lian, Di Lu, Weijun Wan, Xiang Xu
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Developing a multi-modular assembled prime editing (mPE) system improved precise multi-base insertion efficiency in dicots J. Adv. Res. (IF 11.4) Pub Date : 2024-06-26 Pengjun Lu, Erwei Zuo, Jianbin Yan
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Transcriptomic profiling of gastrointestinal tracts in dairy cattle during lactation reveals molecular adaptations for milk synthesis J. Adv. Res. (IF 11.4) Pub Date : 2024-06-24 Yahui Gao, George E. Liu, Li Ma, Lingzhao Fang, Cong-jun Li, Ransom L. Baldwin VI
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WWP2 deletion aggravates acute kidney injury by targeting CDC20/autophagy axis J. Adv. Res. (IF 11.4) Pub Date : 2024-06-22 Ran You, Yanwei Li, Yuteng Jiang, Dandan Hu, Menglei Gu, Wei Zhou, Shengnan Zhang, Mi Bai, Yunwen Yang, Yue Zhang, Songming Huang, Zhanjun Jia, Aihua Zhang
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Targeting the STAT3/IL-36G signaling pathway can be a promising approach to treat rosacea J. Adv. Res. (IF 11.4) Pub Date : 2024-06-22 Xin Meng, Yun Zhong, Xuyuan Kuang, Yiya Zhang, Li Yang, Yisheng Cai, Fan Wang, Fanping He, Hongfu Xie, Ben Wang, Ji Li
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High-dimensional propensity score and its machine learning extensions in residual confounding control Am. Stat. (IF 1.8) Pub Date : 2024-06-17 Mohammad Ehsanul Karim
“The use of health care claims datasets often encounters criticism due to the pervasive issues of omitted variables and inaccuracies or mis-measurements in available confounders. Ultimately, the tr...
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Integrative data analysis where partial covariates have complex non-linear effects by using summary information from an external data Am. Stat. (IF 1.8) Pub Date : 2024-06-17 Jia Liang, Shuo Chen, Peter Kochunov, L. Elliot Hong, Chixiang Chen
A full parametric and linear specification may be insufficient to capture complicated patterns in studies exploring complex features, such as those investigating age-related changes in brain functi...
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Osteoprotegerin mediates adipogenesis in obesity J. Adv. Res. (IF 11.4) Pub Date : 2024-06-19 Zipan Lyu, Yau-Tuen Chan, Yuanjun Lu, Tsz Fung Lam, Xingyao Wu, Junyu Wu, Lin Xu, Wei Yang, Cheng Zhang, Linda Lidan Zhong, Ning Wang
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Kynurenine acts as a signaling molecule to attenuate pulmonary fibrosis by enhancing the AHR-PTEN axis J. Adv. Res. (IF 11.4) Pub Date : 2024-06-19 Yi Wang, Guo-Rao Wu, Huihui Yue, Qing Zhou, Lei Zhang, Long He, Weikuan Gu, Rongfen Gao, Lingli Dong, Huilan Zhang, Jianping Zhao, Xiansheng Liu, Weining Xiong, Cong-Yi Wang
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Nanoparticle-mediated celastrol ER targeting delivery amplify immunogenic cell death in melanoma J. Adv. Res. (IF 11.4) Pub Date : 2024-06-18 Fengling Wang, Wenjing Lai, Dandan Xie, Min Zhou, Jie Wang, Rufu Xu, Rong Zhang, Guobing Li
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Pyroptosis: A spoiler of peaceful coexistence between cells in degenerative bone and joint diseases J. Adv. Res. (IF 11.4) Pub Date : 2024-06-13 Zhichao Li, Wenxiang Cheng, Kuanhui Gao, Songlin Liang, Liqing Ke, Mengjie Wang, Jilin Fan, Dandan Li, Peng Zhang, Zhanwang Xu, Nianhu Li
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Targeting colorectal cancer at the level of nuclear pore complex J. Adv. Res. (IF 11.4) Pub Date : 2024-06-13 Muhammad Mahtab Aslam Khan Khakwani, Xin-Ying Ji, Saadullah Khattak, Ying-Chuan Sun, Kunhou Yao, Lei Zhang
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Hippo-YAP/TAZ-ROS signaling axis regulates metaflammation induced by SelenoM deficiency in high-fat diet-derived obesity J. Adv. Res. (IF 11.4) Pub Date : 2024-06-13 Jingzeng Cai, Jiaqiang Huang, Di Li, Xintong Zhang, Bendong Shi, Qiaohan Liu, Cheng Fang, Shiwen Xu, Ziwei Zhang
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Associations between specific dietary patterns, gut microbiome composition, and incident subthreshold depression in Chinese young adults J. Adv. Res. (IF 11.4) Pub Date : 2024-06-13 Xiumin Jiang, Xiaotong Wang, Meng Zhang, Lin Yu, Jun He, Shengwei Wu, Jinglan Yan, Yuanjia Zheng, Yuanyuan Zhou, Yongjun Chen
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Tumor microenvironment as niche constructed by cancer stem cells: Breaking the ecosystem to combat cancer J. Adv. Res. (IF 11.4) Pub Date : 2024-06-10 Hao Zhong, Shiyue Zhou, Shuangshuang Yin, Yuling Qiu, Bo Liu, Haiyang Yu
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Genetic and phenotypic associations of frailty with cardiovascular indicators and behavioral characteristics J. Adv. Res. (IF 11.4) Pub Date : 2024-06-09 Yihan Chen, Siying Lin, Shuangyu Yang, Mengling Qi, Yu Ren, Chong Tian, Shitian Wang, Yuedong Yang, Jianzhao Gao, Huiying Zhao
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A trans-acting sRNA SaaS targeting hilD, cheA and csgA to inhibit biofilm formation of S. Enteritidis J. Adv. Res. (IF 11.4) Pub Date : 2024-06-07 Chongyang Lyu, Haijing Hu, Linlin Cai, Shuwen He, Xinglian Xu, Guanghong Zhou, Huhu Wang
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Assessment and Continuous Improvement of an Undergraduate Data Science Program Am. Stat. (IF 1.8) Pub Date : 2024-06-07 Nicholas Clark, Christopher Morrell, Mike Powell
In recent years, there has been an explosion in the growth of undergraduate statistics and data science programs across the US. Simultaneously, there has been clear guidance written on curriculum d...
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Synergistic effects of laser powder bed fusion and annealing on the texture-selective recrystallization of magnetostrictive Fe-Ga-NbC alloys for biomedical applications J. Adv. Res. (IF 11.4) Pub Date : 2024-06-05 Chengde Gao, Qi Zeng, Youwen Deng, Shuping Peng, Cijun Shuai
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Prevention and treatment of antibiotics-associated adverse effects through the use of probiotics: A review J. Adv. Res. (IF 11.4) Pub Date : 2024-06-04 Shuwei Yang, Jiaqi Qiao, Meng Zhang, Lai-Yu Kwok, Bojana Bogovič Matijašić, Heping Zhang, Wenyi Zhang
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Egypt Genome: Towards an African new genomic era J. Adv. Res. (IF 11.4) Pub Date : 2024-06-04 Khaled Amer, Neveen A. Soliman, Sameh Soror, Yehia Z. Gad, Ahmed Moustafa, Mohamed A. Elmonem, May Amer, Ameera Ragheb, Amira Kotb, Tarek Taha, Wael Ali, Mahmoud Sakr, Khaled Abdel Ghaffar, Scientific Committee Consortium
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GYY4137-induced p65 sulfhydration protects synovial macrophages against pyroptosis by improving mitochondrial function in osteoarthritis development J. Adv. Res. (IF 11.4) Pub Date : 2024-06-04 Jun Ma, Peng Yang, Zhibin Zhou, Tengfei Song, Liang Jia, Xiaofei Ye, Wei Yan, Jiuyi Sun, Tianwen Ye, Lei Zhu
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Estrogen receptor β activation alleviates inflammatory bowel disease by suppressing NLRP3-dependent IL-1β production in macrophages via downregulation of intracellular calcium level J. Adv. Res. (IF 11.4) Pub Date : 2024-06-04 Yanrong Zhu, Yilei Guo, Pengxiang Guo, Jing Zhang, Yue He, Yufeng Xia, Zhifeng Wei, Yue Dai
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Multi-task aquatic toxicity prediction model based on multi-level features fusion J. Adv. Res. (IF 11.4) Pub Date : 2024-06-04 Xin Yang, Jianqiang Sun, Bingyu Jin, Yuer Lu, Jinyan Cheng, Jiaju Jiang, Qi Zhao, Jianwei Shuai
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Regulation of seed germination: ROS, epigenetic, and hormonal aspects J. Adv. Res. (IF 11.4) Pub Date : 2024-06-03 Yakong Wang, Xiangyang Sun, Jun Peng, Fuguang Li, Faiza Ali, Zhi Wang
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IDD10-NAC079 transcription factor complex regulates sheath blight resistance by inhibiting ethylene signaling in rice J. Adv. Res. (IF 11.4) Pub Date : 2024-05-31 Zhuo Li, Huan Chen, De Peng Yuan, Xu Jiang, Zhi Min Li, Si Ting Wang, Tian Ge Zhou, Hong Yao Zhu, Qiang Bian, Xiao Feng Zhu, Yuan Hu Xuan
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Fucoidan alleviates high sucrose-induced metabolic disorders and enhances intestinal homeostasis through modulation of Notch signaling J. Adv. Res. (IF 11.4) Pub Date : 2024-05-31 Jian Liu, Weiqiang Xia, Qifang Wu, Ya Zhang, Yu Wu, Boyang Li, Fangyu Chen, Xueting Du, Siya Wu, Yue Yang, Yitian Gao, Mingjiang Wu, Laijin Su, Haibin Tong
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Unlocking the crucial role of cancer-associated fibroblasts in tumor metastasis: Mechanisms and therapeutic prospects J. Adv. Res. (IF 11.4) Pub Date : 2024-05-31 Yingxue Liu, Xiaoyan Zhang, Wenchao Gu, Hui Su, Xin Wang, Xu Wang, Jiayu Zhang, Midie Xu, Weiqi Sheng
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N-succinyl-chitosan as ecofriendly pesticide carriers: Nano encapsulation and synergistic antifungal effect on 4-hydroxyphenyl-2-propenyl-1-one derivatives based on chalcone structure J. Adv. Res. (IF 11.4) Pub Date : 2024-05-31 Zhi Xia, Qing Zhou, Yu Zhang, Tao Zhang, Wei Xue
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Sympathetic hyperinnervation drives abdominal aortic aneurysm development by promoting vascular smooth muscle cell phenotypic switching J. Adv. Res. (IF 11.4) Pub Date : 2024-05-29 Zhenquan Tang, Jingfang Xie, Ming Jin, Guoquan Wei, Ziwei Fu, Xiajing Luo, Chuling Li, Xiaoqian Jia, Hao Zheng, Lintao Zhong, Xinzhong Li, Junfen Wang, Guojun Chen, Yanmei Chen, Wangjun Liao, Yulin Liao, Jianping Bin, Senlin Huang
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The biomedical application of inorganic metal nanoparticles in aging and aging-associated diseases J. Adv. Res. (IF 11.4) Pub Date : 2024-05-29 Yuqing Meng, Junzhe Zhang, Yanqing Liu, Yongping Zhu, Haining Lv, Fei Xia, Qiuyan Guo, Qianli Shi, Chong Qiu, Jigang Wang
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Almost sharp lower bound for the nodal volume of harmonic functions Comm. Pure Appl. Math. (IF 3.1) Pub Date : 2024-05-29 Alexander Logunov, Lakshmi Priya M. E., Andrea Sartori
This paper focuses on a relation between the growth of harmonic functions and the Hausdorff measure of their zero sets. Let be a real‐valued harmonic function in with and . We prove where the doubling index is a notion of growth defined by This gives an almost sharp lower bound for the Hausdorff measure of the zero set of , which is conjectured to be linear in . The new ingredients of the article are
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Sequential monitoring using the Second Generation P-Value with Type I error controlled by monitoring frequency Am. Stat. (IF 1.8) Pub Date : 2024-05-28 Jonathan J. Chipman, Robert A. Greevy Jr., Lindsay Mayberry, Jeffrey D. Blume
The Second Generation P-Value (SGPV) measures the overlap between an estimated interval and a composite hypothesis of parameter values. We develop a sequential monitoring scheme of the SGPV (SeqSGP...
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A comprehensive review and advanced biomolecule-based therapies for osteoporosis J. Adv. Res. (IF 11.4) Pub Date : 2024-05-27 Maqsood Ali, Yong-Sik Kim
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Cotton transposon-related variome reveals roles of transposon-related variations in modern cotton cultivation J. Adv. Res. (IF 11.4) Pub Date : 2024-05-27 Shang Liu, Hailiang Cheng, Youping Zhang, Man He, Dongyun Zuo, Qiaolian Wang, Limin Lv, Zhongxv Lin, Ji Liu, Guoli Song
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Silicon: A valuable soil element for improving plant growth and CO2 sequestration J. Adv. Res. (IF 11.4) Pub Date : 2024-05-26 Abdul Latif Khan
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Engineering DMNT emission in cotton enhances direct and indirect defense against mirid bugs J. Adv. Res. (IF 11.4) Pub Date : 2024-05-26 Dong Teng, Danfeng Liu, Adel Khashaveh, Beibei Lv, Peiyao Sun, Ting Geng, Hongzhi Cui, Yi Wang, Yongjun Zhang
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SLC7A11 as a therapeutic target to attenuate phthalates-driven testosterone level decline in mice J. Adv. Res. (IF 11.4) Pub Date : 2024-05-24 Yi Zhao, Xue-Qi Wang, Rui-Qi Liu, Fu-Wei Jiang, Jia-Xin Wang, Ming-Shan Chen, Hao Zhang, Jia-Gen Cui, Yuan-Hang Chang, Jin-Long Li
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Residential greenness and chronic obstructive pulmonary disease in a large cohort in southern China: Potential causal links, risk trajectories, and mediation pathways J. Adv. Res. (IF 11.4) Pub Date : 2024-05-24 Wenjing Wu, Dan Chen, Xingling Ruan, Gonghua Wu, Xinlei Deng, Wayne Lawrence, Xiao Lin, Zhiqiang Li, Ying Wang, Ziqiang Lin, Shuming Zhu, Xueqing Deng, Qiaoxuan Lin, Chun Hao, Zhicheng Du, Jing Wei, Wangjian Zhang, Yuantao Hao
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Biosynthesis and functions of triterpenoids in cereals J. Adv. Res. (IF 11.4) Pub Date : 2024-05-23 Jiaojiao Lu, Shan Yan, Zheyong Xue
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Systematic evaluation of single-cell RNA-seq analyses performance based on long-read sequencing platforms J. Adv. Res. (IF 11.4) Pub Date : 2024-05-22 Enze Deng, Qingmei Shen, Jingna Zhang, Yaowei Fang, Lei Chang, Guanzheng Luo, Xiaoying Fan
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On Misuses of the Kolmogorov–Smirnov Test for One-Sample Goodness-of-Fit Am. Stat. (IF 1.8) Pub Date : 2024-05-20 Anthony Zeimbekakis, Elizabeth D. Schifano, Jun Yan
The Kolmogorov–Smirnov (KS) test is widely employed to assess the goodness-of-fit of a hypothesized continuous distribution to a sample. Despite its popularity, the test is frequently misused in th...
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Design of a targeted dual drug delivery system for boosting the efficacy of photoimmunotherapy against melanoma proliferation and metastasis J. Adv. Res. (IF 11.4) Pub Date : 2024-05-19 Yi Chen, Shan Xu, Shuang Ren, Jiyuan Zhang, Jinzhuan Xu, Yuxuan Song, Jianqing Peng, Shuai Zhang, Qianming Du, Yan Chen
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Insight into the composition and differentiation of endophytic microbial communities in kernels via 368 maize transcriptomes J. Adv. Res. (IF 11.4) Pub Date : 2024-05-19 Fang Tao, Feng Chen, Haida Liu, Cheng Chen, Beijiu Cheng, Guomin Han
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Multiplicative chaos measures from thick points of log‐correlated fields Comm. Pure Appl. Math. (IF 3.1) Pub Date : 2024-05-17 Janne Junnila, Gaultier Lambert, Christian Webb
We prove that multiplicative chaos measures can be constructed from extreme level sets or thick points of the underlying logarithmically correlated field. We develop a method which covers the whole subcritical phase and only requires asymptotics of suitable exponential moments for the field. As an application, we establish that these estimates hold for the logarithm of the absolute value of the characteristic
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Twisted Kähler–Einstein metrics in big classes Comm. Pure Appl. Math. (IF 3.1) Pub Date : 2024-05-17 Tamás Darvas, Kewei Zhang
We prove existence of twisted Kähler–Einstein metrics in big cohomology classes, using a divisorial stability condition. In particular, when is big, we obtain a uniform Yau–Tian–Donaldson (YTD) existence theorem for Kähler–Einstein (KE) metrics. To achieve this, we build up from scratch the theory of Fujita–Odaka type delta invariants in the transcendental big setting, using pluripotential theory.
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Allen–Cahn solutions with triple junction structure at infinity Comm. Pure Appl. Math. (IF 3.1) Pub Date : 2024-05-17 Étienne Sandier, Peter Sternberg
We construct an entire solution to the elliptic system where is a ‘triple‐well’ potential. This solution is a local minimizer of the associated energy in the sense that minimizes the energy on any compact set among competitors agreeing with outside that set. Furthermore, we show that along subsequences, the ‘blowdowns’ of given by approach a minimal triple junction as . Previous results had assumed
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Targeting selective autophagy and beyond: From underlying mechanisms to potential therapies J. Adv. Res. (IF 11.4) Pub Date : 2024-05-14 Wei Ma, Yingying Lu, Xin Jin, Na Lin, Lan Zhang, Yaowen Song
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The R2D2 prior for generalized linear mixed models Am. Stat. (IF 1.8) Pub Date : 2024-05-09 Eric Yanchenko, Howard D. Bondell, Brian J. Reich
In Bayesian analysis, the selection of a prior distribution is typically done by considering each parameter in the model. While this can be convenient, in many scenarios it may be desirable to plac...