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The role of trehalose metabolism in plant stress tolerance J. Adv. Res. (IF 11.4) Pub Date : 2024-12-19 Tong-Ju Eh, Yaxuan Jiang, Mingquan Jiang, Jianxin Li, Pei Lei, Ximei Ji, Hyon-Il Kim, Xiyang Zhao, Fanjuan Meng
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Maternal fish oil supplementation enhances placental nutrient transport and mammary gland secretion via the GPR120 signaling pathway J. Adv. Res. (IF 11.4) Pub Date : 2024-12-19 Qihui Li, Qianzi Zhang, Senlin Su, Siwang Yang, Jiayuan Shao, Wutai Guan, Shihai Zhang
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Targeting ATM enhances radiation sensitivity of colorectal cancer by Potentiating radiation-induced cell death and antitumor immunity J. Adv. Res. (IF 11.4) Pub Date : 2024-12-19 Yuwen Xie, Yang Liu, Mingdao Lin, Zhenkang Li, Zhiyong Shen, Shengqi Yin, Yilin Zheng, Yishu Zou, Yaowei Zhang, Yizhi Zhan, Yuan Fang, Yi Ding
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Biomechanical research using advanced micro-nano devices: In-Vitro cell Characterization focus J. Adv. Res. (IF 11.4) Pub Date : 2024-12-17 Shiqiang Yan, Yan Lu, Changming An, Wanglai Hu, Yaofeng Chen, Ziwen Li, Wenbo Wei, Zongzheng Chen, Xianhai Zeng, Wei Xu, Zhenghua Lv, Fan Pan, Wei Gao, Yongyan Wu
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FTO activates PD-L1 promotes immunosuppression in breast cancer via the m6A/YTHDF3/PDK1 axis under hypoxic conditions J. Adv. Res. (IF 11.4) Pub Date : 2024-12-17 Siyu Wang, Xingda Zhang, Quanrun Chen, Hao Wu, Shihan Cao, Shilu Zhao, Guozheng Li, Jianyu Wang, Yajie Gong, Xinheng Wang, Da Pang, Song Gao
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An AP2/ERF transcription factor controls generation of the twin-seedling rice J. Adv. Res. (IF 11.4) Pub Date : 2024-12-17 Kaichong Teng, Neng Zhao, Yonghong Xie, Rongbai Li, Jianxiong Li
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Exploring the mediating roles of depression and cognitive function in the association between sarcopenia and frailty: A Cox survival analysis approach J. Adv. Res. (IF 11.4) Pub Date : 2024-12-17 Yan Zhu, Haojie Yin, Xianli Zhong, Qin Zhang, Li Wang, Rong Lu, Ping Jia
BackgroundDespite earlier research indicating a potential link between the development of sarcopenia and an elevated risk of frailty, the lack of comprehensive prospective data on the correlation between sarcopenia and frailty incidence leaves open the question of whether depression and cognitive function mediate this association. ObjectiveThe principal aim of the current investigation was to evaluate
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Selective Regulation of ray tissue for achieving ultrastable Zero-Poisson’s-ratio material out of wood J. Adv. Res. (IF 11.4) Pub Date : 2024-12-15 Xia Yu, Xinyi Zhou, Tong Wu, Bohua Ren, Tao Fang, Chaonan Cong, Guofang Wu, Lihong Yao, Xiaoding Wei, Bo Liu, Yun Lu
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Advances in statin adverse reactions and the potential mechanisms: A review J. Adv. Res. (IF 11.4) Pub Date : 2024-12-14 Weiwei Zeng, Huan Deng, Yuning Luo, Shilong Zhong, Min Huang, Brian Tomlinson
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Natural small molecule hinokitone mitigates NASH fibrosis by targeting regulation of FXR-mediated hepatocyte apoptosis J. Adv. Res. (IF 11.4) Pub Date : 2024-12-13 Ze-Jiang Ma, Ying-Kun Qiu, Zhe-Wei Yu, Tian-Tian Song, Yi-Tong Hu, An-Kang Peng, Rong Qi
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Improving grain yield and salt tolerance by optimizing plant height with beneficial haplotypes in rice (Oryza sativa) J. Adv. Res. (IF 11.4) Pub Date : 2024-12-12 Ruidang Quan, Juan Wang, Hua Qin, Liang Chen, Dinglin Xiao, Zihan Zhao, Zhanying Zhang, Xiaoyang Zhu, Zichao Li, Rongfeng Huang
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Insulin-like growth factor binding protein 7 identified in aged dental pulp by single-cell RNA sequencing J. Adv. Res. (IF 11.4) Pub Date : 2024-12-12 Zhongchun Tong, Jie Wu, Qimei Gong, Yifang Yuan, Shengchao Wang, Wenkai Jiang
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Soybean nodulation shapes the rhizosphere microbiome to increase rapeseed yield J. Adv. Res. (IF 11.4) Pub Date : 2024-12-12 Yu Liu, Qin Han, Jiaming Zhang, Xuehai Zhang, Yuqin Chen, Mingbo Li, Yongfang Hao, Yujie Hong, Ruizhen Tang, Brett J. Ferguson, Peter M. Gresshoff, Jie Kuai, Guangsheng Zhou, Xia Li, Hongtao Ji
IntroductionCrop rotation, a crucial agricultural practice that enhances soil health and crop productivity, is widely used in agriculture worldwide. Soybeans play a crucial role in crop rotation owing to their nitrogen-fixing ability, which is facilitated by symbiotic bacteria in their root systems. The soybean-rapeseed rotation is an effective agricultural practice in the Yangtze River Basin of China
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Predictive value of remnant cholesterol inflammatory index for stroke risk: Evidence from the China health and Retirement Longitudinal study J. Adv. Res. (IF 11.4) Pub Date : 2024-12-12 Jiaying Chen, Qiheng Wu, Haotian Liu, Weike Hu, JiaJia Zhu, Zhong Ji, Jia Yin
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Bio-friendly multi-stimuli responsive α-CD polymer-gated mesoporous carbon nanoherbicides for enhanced paraquat delivery J. Adv. Res. (IF 11.4) Pub Date : 2024-12-12 Jiangtao Dong, Guoquan Wang, Xiaona Li, Anhui Han, Wanpeng Zhang, Yuhang Yue, Yue Yang, Yishan Wang, Bowen Yuan, Jiahui Wang, Yuhui Peng, Runqiang Liu, Si Chen, Xuezhong Du
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Macrophage P2Y12 regulates iron transport and its inhibition protects against atherosclerosis J. Adv. Res. (IF 11.4) Pub Date : 2024-12-12 Yang-Xi Hu, Hong-Min You, Mei-Rong Bai, Wen-Heng Yue, Fang-Fang Li, Bo-Wen Hu, Ya-Sha Chen, Xiang-Yu Shen, Yue Wu, Jia-Mei Wang, Zhi-Qing He, Xia Tao, Qing Jing, Chun Liang
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Genome-wide profiling and functional study of short N-terminal H2B variants in Arabidopsis J. Adv. Res. (IF 11.4) Pub Date : 2024-12-11 Peng Yao, Qin He, Ying Wang, Danyang Sun, Xiangsong Chen, Li Lu
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CD34+CLDN5+ tumor associated senescent endothelial cells through IGF2-IGF2R signaling increased cholangiocellular phenotype in hepatocellular carcinoma J. Adv. Res. (IF 11.4) Pub Date : 2024-12-12 Xin-yu Zhu, Wen-ting Liu, Xiao-juan Hou, Chen Zong, Wei Yua, Zhe-min Shen, Shu-ping Qu, Min Tao, Meng-meng Xue, Dao-yu Zhou, Hao-ran Bai, Lu Gao, Jing-hua Jiang, Qiu-dong Zhao, Li-xin Wei, Xue Yang, Zhi-peng Han, Li Zhang
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A dual‐space multilevel kernel‐splitting framework for discrete and continuous convolution Comm. Pure Appl. Math. (IF 3.1) Pub Date : 2024-12-12 Shidong Jiang, Leslie Greengard
We introduce a new class of multilevel, adaptive, dual‐space methods for computing fast convolutional transformations. These methods can be applied to a broad class of kernels, from the Green's functions for classical partial differential equations (PDEs) to power functions and radial basis functions such as those used in statistics and machine learning. The DMK (dual‐space multilevel kernel‐splitting)
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KBTBD8/RRP15 as a potential novel therapeutic target associates with lenvatinib-inhibited progression in hepatocellular carcinoma both in vitro and in vivo J. Adv. Res. (IF 11.4) Pub Date : 2024-12-11 Saili Zhao, Xuran Wang, Rui Wu, Fenglan Wang, Xiaoxuan Tang, Junhui Chen, Runqiu Jiang, Wei Kang, Guifang Xu, Lei Wang, Zhangding Wang, Xiaoping Zou, Bin Zhang
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Dissecting the anti-obesity components of ginseng: How ginseng polysaccharides and ginsenosides target gut microbiota to suppress high-fat diet-induced obesity J. Adv. Res. (IF 11.4) Pub Date : 2024-12-11 Han-Yan Luo, Jing Fang, Wei-Hao Zhang, Kam-Chun Chan, Yui-Man Chan, Cai-Xia Dong, Song-Lin Li, Ai-Ping Lyu, Jun Xu
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Key β1-4 galactosylated glycan receptors of SARS-CoV-2 and its inhibitor from the galactosylated glycoproteins of bovine milk J. Adv. Res. (IF 11.4) Pub Date : 2024-12-10 Hanjie Yu, Wentian Chen, Jian Shu, Xin Wu, Jia Quan, Hongwei Cheng, Xiaojuan Bao, Di Wu, Xilong Wang, Zheng Li
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ORP5 promotes cardiac hypertrophy by regulating the activation of mTORC1 on lysosome J. Adv. Res. (IF 11.4) Pub Date : 2024-12-10 Di Zhao, Ran Xu, Yufei Zhou, Jiaying Wu, Xiaoxue Zhang, Hong Lin, Jienan Wang, Zhiwen Ding, Yunzeng Zou
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Not only the top: Type I topoisomerases function in multiple tissues and organs development in plants J. Adv. Res. (IF 11.4) Pub Date : 2024-12-09 Hao Zhang, Lirong Tian, Yuru Ma, Jiahui Xu, Tianyu Bai, Qian Wang, Xigang Liu, Lin Guo
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Dual regulation of phaseol on osteoclast formation and osteoblast differentiation by targeting TAK1 kinase for osteoporosis treatment J. Adv. Res. (IF 11.4) Pub Date : 2024-12-09 Lihua Tan, Zhimin Miao, Yuxin Zhao, Yongkai Liang, Nan Xu, Xin Chen, Yanbei Tu, Chengwei He
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Cancer-associated fibroblasts regulate mitochondrial metabolism and inhibit chemosensitivity via ANGPTL4-IQGAP1 axis in prostate cancer J. Adv. Res. (IF 11.4) Pub Date : 2024-12-06 Zhi Xiong, Rui-Lin Zhuang, Shun-Li Yu, Zhao-Xiang Xie, Shi-Rong Peng, Ze-An Li, Bing-Heng Li, Jun-Jia Xie, Yi-Ning Li, Kai-Wen Li, Hai Huang
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Ubiquitin proteasome system in cardiac fibrosis J. Adv. Res. (IF 11.4) Pub Date : 2024-12-07 Linqi Zeng, Xiaokai Zhang, Zihang Huang, Shuai Song, Mohan Li, Tongyao Wang, Aijun Sun, Junbo Ge
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Asperosaponin VI inhibition of DNMT alleviates GPX4 suppression-mediated osteoblast ferroptosis and diabetic osteoporosis J. Adv. Res. (IF 11.4) Pub Date : 2024-12-06 Fanhao Wei, Binjia Ruan, Jian Dong, Bin Yang, Guofu Zhang, Wai Kwok Kelvin Yeung, Hongwei Wang, Wangsen Cao, Yongxiang Wang
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Unlocking biological insights from differentially expressed genes: Concepts, methods, and future perspectives J. Adv. Res. (IF 11.4) Pub Date : 2024-12-06 Huachun Yin, Hongrui Duo, Song Li, Dan Qin, Lingling Xie, Yingxue Xiao, Jing Sun, Jingxin Tao, Xiaoxi Zhang, Yinghong Li, Yue Zou, Qingxia Yang, Xian Yang, Youjin Hao, Bo Li
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On the isoperimetric Riemannian Penrose inequality Comm. Pure Appl. Math. (IF 3.1) Pub Date : 2024-12-06 Luca Benatti, Mattia Fogagnolo, Lorenzo Mazzieri
We prove that the Riemannian Penrose inequality holds for asymptotically flat 3‐manifolds with nonnegative scalar curvature and connected horizon boundary, provided the optimal decay assumptions are met, which result in the mass being a well‐defined geometric invariant. Our proof builds on a novel interplay between the Hawking mass and a potential‐theoretic version of it, recently introduced by Agostiniani
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Hypo-osmolarity promotes naive pluripotency by reshaping cytoskeleton and increasing chromatin accessibility J. Adv. Res. (IF 11.4) Pub Date : 2024-12-04 Renhong Lu, Bowen Lin, Zheyi Lin, Hui Xiong, Junyang Liu, Li Li, Zheng Gong, Siyu Wang, Mingshuai Zhang, Jie Ding, Chengwen Hang, Huixin Guo, Duanyang Xie, Yi Liu, Dan Shi, Dandan Liang, Zhen Liu, Jian Yang, Yi-Han Chen
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Randomly pivoted Cholesky: Practical approximation of a kernel matrix with few entry evaluations Comm. Pure Appl. Math. (IF 3.1) Pub Date : 2024-12-04 Yifan Chen, Ethan N. Epperly, Joel A. Tropp, Robert J. Webber
The randomly pivoted Cholesky algorithm (RPCholesky) computes a factorized rank‐ approximation of an positive‐semidefinite (psd) matrix. RPCholesky requires only entry evaluations and additional arithmetic operations, and it can be implemented with just a few lines of code. The method is particularly useful for approximating a kernel matrix. This paper offers a thorough new investigation of the empirical
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Targeting Dlat-Trpv3 pathway by hyperforin elicits non-canonical promotion of adipose thermogenesis as an effective anti-obesity strategy J. Adv. Res. (IF 11.4) Pub Date : 2024-12-02 Sijia Lu, Quanxin Jiang, Peihui Zhou, Limin Yin, Ning Wang, Junting Xu, Qiqi Qian, Mijia Tao, Hanrui Yin, Liu Han, Yunqing Gu, Fei Gao, Junli Liu, Suzhen Chen
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The potential of circular RNAs as biomarkers and therapeutic targets for gastric cancer: A comprehensive review J. Adv. Res. (IF 11.4) Pub Date : 2024-11-29 Junlin Pu, Xiuli Yan, Hui Zhang
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Full dimensional dynamic 3D convolution and point cloud in pulmonary nodule detection J. Adv. Res. (IF 11.4) Pub Date : 2024-11-29 Yun Tie, Ying Wang, Dalong Zhang, Zepeng Zhang, Fenghui Liu, Lin Qi
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Exercise-regulated lipolysis: Its role and mechanism in health and diseases J. Adv. Res. (IF 11.4) Pub Date : 2024-11-28 Jie-Ying Zhu, Liang Guo
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Fungus-derived opine enhances plant photosynthesis J. Adv. Res. (IF 11.4) Pub Date : 2024-11-25 Dekun Kong, Li Cui, Xiaozheng Wang, Jing Wo, Fangjie Xiong
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Manipulation of artificial light environment improves plant biomass and fruit nutritional quality in tomato J. Adv. Res. (IF 11.4) Pub Date : 2024-11-24 Ying Zhang, Kangyou Zhu, Xiujie Wang, Jiarong Yan, Haiyan Zhu, Nan Zhang, Yiting Wang, Qi Zhao, Yanan Liu, Xin Bu, Chenghao Jiang, Xin Sun, Golam Jalal Ahammed, Shuyu Cai, Sida Meng, Zhouping Sun, Mingfang Qi, Tianlai Li, Feng Wang
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Trends, clinicopathological features, surgical treatment patterns and prognoses of early-onset versus late-onset gastric cancer: A retrospective cohort study J. Adv. Res. (IF 11.4) Pub Date : 2024-11-24 Yingxue Liu, Xiaoyan Zhang, Lu Gan, Zhikai Chen, Xin Wang, Jiayu Zhang, Jie Chen, Cong Tan, Weiqi Sheng, Midie Xu
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Hydrodynamic large deviations of TASEP Comm. Pure Appl. Math. (IF 3.1) Pub Date : 2024-11-22 Jeremy Quastel, Li‐Cheng Tsai
We consider the large deviations from the hydrodynamic limit of the Totally Asymmetric Simple Exclusion Process (TASEP). This problem was studied by Jensen and Varadhan and was shown to be related to entropy production in the inviscid Burgers equation. Here we prove the full large deviation principle. Our method relies on the explicit formula of Matetski, Quastel, and Remenik for the transition probabilities
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On the derivation of the homogeneous kinetic wave equation Comm. Pure Appl. Math. (IF 3.1) Pub Date : 2024-11-21 Charles Collot, Pierre Germain
The nonlinear Schrödinger equation in the weakly nonlinear regime with random Gaussian fields as initial data is considered. The problem is set on the torus in any dimension greater than two. A conjecture in statistical physics is that there exists a kinetic time scale depending on the frequency localization of the data and on the strength of the nonlinearity, on which the expectation of the squares
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miR-3606-3p alleviates skin fibrosis by integratively suppressing the integrin/FAK, p-AKT/p-ERK, and TGF-β signaling cascades J. Adv. Res. (IF 11.4) Pub Date : 2024-11-20 Yahui Chen, Yiyi Gong, Mengkun Shi, Haoxing Zhu, Yulong Tang, Delin Huang, Wei Wang, Chenyi Shi, Xueyi Xia, Ying Zhang, Jianlan Liu, Jia Huang, Mengguo Liu, Huyan Chen, Yanyun Ma, Ziyu Wang, Lei Wang, Wenzhen Tu, Yinhuan Zhao, Jinran Lin, Li Jin, Jörg HW Distler, Wenyu Wu, Jiucun Wang, Xiangguang Shi
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On the stability of Runge–Kutta methods for arbitrarily large systems of ODEs Comm. Pure Appl. Math. (IF 3.1) Pub Date : 2024-11-20 Eitan Tadmor
We prove that Runge–Kutta (RK) methods for numerical integration of arbitrarily large systems of Ordinary Differential Equations are linearly stable. Standard stability arguments—based on spectral analysis, resolvent condition or strong stability, fail to secure the stability of RK methods for arbitrarily large systems. We explain the failure of different approaches, offer a new stability theory based
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Interleukin-10 deficiency suppresses colorectal cancer metastasis by enriching gut Parabacteroides distasonis J. Adv. Res. (IF 11.4) Pub Date : 2024-11-19 Jing Yu, Lili Feng, Zhanhao Luo, Jingyi Yang, Qiang Zhang, Chen Liu, Dayi Liang, Yanchun Xie, Hongmin Li, Junli Gong, Zhen He, Ping Lan
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An accurate prediction for respiratory diseases using deep learning on bronchoscopy diagnosis images J. Adv. Res. (IF 11.4) Pub Date : 2024-11-19 Weiling Sun, Pengfei Yan, Minglei Li, Xiang Li, Yuchen Jiang, Hao Luo, Yanbin Zhao
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Bacteroides uniformis ameliorates pro-inflammatory diet-exacerbated colitis by targeting endoplasmic reticulum stress-mediated ferroptosis J. Adv. Res. (IF 11.4) Pub Date : 2024-11-19 Caiguang Liu, Linxin Liu, Zhenyi Tian, Shukai Zhan, Yun Qiu, Manying Li, Tong Li, Ren Mao, Shenghong Zhang, Minhu Chen, Zhirong Zeng, Xiaojun Zhuang
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Self-adhesion conductive cardiac patch based on methoxytriethylene glycol-functionalized graphene effectively improves cardiac function after myocardial infarction J. Adv. Res. (IF 11.4) Pub Date : 2024-11-19 Xu Wang, Hao Wang, Xin Liu, Yuan Zhang, Jiamin Li, Heng Liu, Jing Feng, Wenqian Jiang, Ling Liu, Yongchao Chen, Xiaohan Li, Limin Zhao, Jing Guan, Yong Zhang
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Transient receptor potential channels in viral infectious diseases: Biological characteristics and regulatory mechanisms J. Adv. Res. (IF 11.4) Pub Date : 2024-11-17 Wen-Hui Qi, Na Tang, Zhi-Jing Zhao, Xiao-Qiang Li
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Kaempferol regulating macrophage foaming and atherosclerosis through Piezo1-mediated MAPK/NF-κB and Nrf2/HO-1 signaling pathway J. Adv. Res. (IF 11.4) Pub Date : 2024-11-17 Tianjiao Chu, Yuman Wang, Shihao Wang, Jinze Li, Zheng Li, Zihao Wei, Jing Li, Yifei Bian
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Generalized deep learning for histopathology image classification using supervised contrastive learning J. Adv. Res. (IF 11.4) Pub Date : 2024-11-16 Md Mamunur Rahaman, Ewan K.A. Millar, Erik Meijering
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An efficient discrete Chebyshev polynomials strategy for tempered time fractional nonlinear Schrödinger problems J. Adv. Res. (IF 11.4) Pub Date : 2024-11-16 Mohammad Hossein Heydari, Dumitru Baleanu
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Attention over vulnerable brain regions associating cerebral palsy disorder and biological markers J. Adv. Res. (IF 11.4) Pub Date : 2024-11-16 Muhammad Hassan, Jieqiong Lin, Ahmed Ameen Fateh, Wei Pang, Luning Zhang, Di Wang, Guojun Yun, Hongwu Zeng
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Glycyrrhiza, a commonly used medicinal herb: Review of species classification, pharmacology, active ingredient biosynthesis, and synthetic biology J. Adv. Res. (IF 11.4) Pub Date : 2024-11-16 Liwei Wu, Tingyu Ma, Chenxi Zang, Zhichao Xu, Wei Sun, Hongmei Luo, Meihua Yang, Jingyuan Song, Shilin Chen, Hui Yao
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Mean‐field limit of non‐exchangeable systems Comm. Pure Appl. Math. (IF 3.1) Pub Date : 2024-11-16 Pierre‐Emmanuel Jabin, David Poyato, Juan Soler
This paper deals with the derivation of the mean‐field limit for multi‐agent systems on a large class of sparse graphs. More specifically, the case of non‐exchangeable multi‐agent systems consisting of non‐identical agents is addressed. The analysis does not only involve PDEs and stochastic analysis but also graph theory through a new concept of limits of sparse graphs (extended graphons) that reflect
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The α$\alpha$‐SQG patch problem is illposed in C2,β$C^{2,\beta }$ and W2,p$W^{2,p}$ Comm. Pure Appl. Math. (IF 3.1) Pub Date : 2024-11-16 Alexander Kiselev, Xiaoyutao Luo
We consider the patch problem for the ‐(surface quasi‐geostrophic) SQG system with the values and being the 2D Euler and the SQG equations respectively. It is well‐known that the Euler patches are globally wellposed in non‐endpoint Hölder spaces, as well as in , spaces. In stark contrast to the Euler case, we prove that for , the ‐SQG patch problem is strongly illposed in every Hölder space with .
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Astragaloside IV alleviates septic myocardial injury through DUSP1-Prohibitin 2 mediated mitochondrial quality control and ER-autophagy J. Adv. Res. (IF 11.4) Pub Date : 2024-11-15 Junyan Wang, Xiangyi Pu, Haowen Zhuang, Zhijiang Guo, Mengyuan Wang, Huaihong Yang, Chun Li, Xing Chang
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Semiconvexity estimates for nonlinear integro‐differential equations Comm. Pure Appl. Math. (IF 3.1) Pub Date : 2024-11-15 Xavier Ros‐Oton, Clara Torres‐Latorre, Marvin Weidner
In this paper we establish for the first time local semiconvexity estimates for fully nonlinear equations and for obstacle problems driven by integro‐differential operators with general kernels. Our proof is based on the Bernstein technique, which we develop for a natural class of nonlocal operators and consider to be of independent interest. In particular, we solve an open problem from Cabré‐Dipierro‐Valdinoci