Correction to: Nature https://doi.org/10.1038/s41586-024-08439-0 Published online 22 January 2025

An analysis of how various tissues age is the latest to suggest that ageing does not march to a steady beat.

Study of rotting human cadavers hints that a puzzling chemical marker in Neanderthal remains could be from eating the larvae.

Data sleuths and research-integrity officers have different views on how to handle allegations of wrongdoing in science.

Decreased funding, reduced opportunities and growing uncertainty has made life tough for international postdocs living in the US.

The Tintina fault has triggered many more earthquakes than was thought — and a build-up of strain poses a hazard.

A landmark court ruling could open the door for nations most affected by climate change to sue the most polluting countries. Plus, an artificial intelligence model that can predict lost Latin text and a fish-inspired medical device that sticks to slippery surfaces.

New Canary Islands home could save controversial Thirty Meter Telescope first proposed for Hawaii.

The journal Science retracts a headline-grabbing study, but the authors vigorously defend their data and say the retraction is unwarranted.

Correction to: Nature https://doi.org/10.1038/s41586-024-08248-5 Published online 20 November 2024

The device could be swallowed for drug delivery or medical monitoring.

For the first time, large language models performed on a par with gold medallists in the International Mathematical Olympiad.

It took time and rejections to understand what granting agencies look for. This is how I picked up application-writing skills.

The multi-layered nucleolus serves as the primary site of ribosome biogenesis1,2, where successive maturation of small (SSU)3,4 and large (LSU)5 ribosomal subunit precursors occur. However, the spatio-functional relationship between pre-rRNA processing and nucleolar substructures and how this adapts to changing cellular physiological demands have remained incompletely understood6,7. Here, our spatiotemporal

Hear the biggest stories from the world of science | 23 July 2025

A month of treatment increased a patient’s walking endurance from 10–30 metres to more than 2 kilometres.

The Trump administration plans the departure for the end of 2026 and criticizes the UN Sustainable Development Goals.

Although large, elongated protrusions on a 247-million-year-old reptile fossil have some similarities to feathers, they are not feathers.

A long-standing mystery about a pathway that makes a key defence molecule in various valuable crop plants is finally solved.

All optimists’ brain patterns are alike, but each pessimist’s brain is unhappy in its own way. Plus, the COVID-19 pandemic accelerated brain ageing and how tenure affects publication output.

Heating that lasted only trillionths of a second raised a gold sample’s temperature to 19,000 K without melting it, a study suggests.

An artificial-intelligence tool helps historians to interpret Latin inscriptions by assigning a date and location and suggesting text for missing parts.

The best results come when a human and the model work together.

Lasers have been used to heat solid gold well beyond its melting temperature without losing the metal’s crystalline structure — exceeding a theoretical superheating limit.

Deep-sea brittlestars are more evolutionarily connected around the globe than previously thought.

Class I major histocompatibility complex (MHC-I) molecules present peptides derived from intracellular antigens on the cell surface for immune surveillance. Proteins that recognize peptide–MHC-I (pMHCI) complexes with specificity for diseased cells could have considerable therapeutic utility. Specificity requires recognition of outward-facing amino acid residues within the disease-associated peptide

Twisted two-dimensional materials exhibit distinctive vibrational modes called moiré phonons, which arise from the moiré superlattice. Here, we demonstrate atom-by-atom imaging of phasons, an ultrasoft class of moiré phonons in twisted bilayer tungsten diselenide (WSe 2 ). Using ultrahigh-resolution (<15 picometers) electron ptychography, we imaged the size and shape of each atom to extract time-averaged

The year 2023 witnessed an extraordinary surge in marine heatwaves (MHWs) across Earth’s oceans, setting new records in duration, extent, and intensity, with MHW activity totaling 53.6 billion °C days square kilometer—more than three standard deviations above the historical norm since 1982. Notable events include the North Atlantic MHW (276-year return period) and the Southwest Pacific (141 years)

T cell receptor (TCR) mimics offer a promising platform for tumor-specific targeting of peptide–major histocompatibility complex (pMHC) in cancer immunotherapy. In this study, we designed a de novo α-helical TCR mimic (TCRm) specific for the NY-ESO-1 peptide presented by human leukocyte antigen (HLA)–A*02, achieving high on-target specificity with nanomolar affinity (dissociation constant K d = 9.5

Charting the spatiotemporal dynamics of cell fate determination in development and disease is a long-standing objective in biology. Here we present the design, development, and extensive validation of PEtracer, a prime editing-based, evolving lineage tracing technology compatible with both single-cell sequencing and multimodal imaging methodologies to jointly profile cell state and lineage in dissociated

Small molecules are used to target the insulin signaling molecular machinery.

The recognition of intracellular antigens by CD8 + T cells through T cell receptors (TCRs) is central for adaptive immunity against infections and cancer. However, the identification of TCRs from patient material remains complex. We present a rapid de novo minibinder (miBd) design platform leveraging state-of-the-art generative models to engineer miBds targeting the cancer-associated peptide-bound

Multiphoton interference and entanglement are fundamental to quantum information science, yet extending these effects to higher-dimensional systems remains challenging given the imperfections and complexity of scaling conventional linear-optical setups. We present a generalized Hong-Ou-Mandel effect using metasurfaces and graph theory, achieving controlled multiphoton bunching, antibunching, and entanglement

The challenge of producing food at low monetary cost comes with high environmental impacts as yield maximization by excessive fertilization and chemical pest control drive farmers away from using the natural multifunctional potential of soils. We show how the ecological concept of plant-soil feedback can be used to restore the capacity of agricultural soils to provide nutrients, suppress pathogens