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1H-nuclear magnetic resonance analysis reveals dynamic changes in the metabolic profile of patients with severe burns Burns Trauma (IF 5.3) Pub Date : 2024-05-16 Sen Su, Yong Zhang, Dan Wu, Chao Wang, Jianhong Hu, Yan Wei, Xi Peng
Background Severe burn injury causes a hypermetabolic response, resulting in muscle protein catabolism and multiple organ damage syndrome. However, this response has not yet been continuously characterized by metabolomics in patients. This study aims to quantify temporal changes in the metabolic processes of patients with severe burns. Methods We employed 1H-nuclear magnetic resonance (NMR) spectroscopy
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Explorative study on lower inflection point dynamics during cardiopulmonary resuscitation: Potential implications for airway management Resuscitation (IF 6.5) Pub Date : 2024-05-15 Arthur Bouillon, Maxim Vanwulpen, Thomas Tackaert, Ruben Cornelis, Said Hachimi-Idrissi
In patients undergoing cardiopulmonary resuscitation (CPR) after an Out-of-Hospital Cardiac Arrest (OHCA), intrathoracic airway closure can impede ventilation, adversely affecting patient outcomes. This explorative study investigates the evolution of intrathoracic airway closure by analyzing the lower inflection point (LIP) during the inspiration phase of CPR, aiming to identify the potential thresholds
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Development and preliminary assessment of a machine learning model to predict myocardial infarction and cardiac arrest after major operations Resuscitation (IF 6.5) Pub Date : 2024-05-15 Yas Sanaiha, Arjun Verma, Ayesha P. Ng, Joseph Hadaya, Clifford Y Ko, Christian deVirgilio, Peyman Benharash
Accurate prediction of complications often informs shared decision-making. Derived over 10 years ago to enhance prediction of intra/post-operative myocardial infarction and cardiac arrest (MI/CA), the Gupta score has been criticized for unreliable calibration and inclusion of a wide spectrum of unrelated operations. In the present study, we developed a novel machine learning (ML) model to estimate
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Exosome-mimetic vesicles derived from fibroblasts carrying matrine for wound healing Burns Trauma (IF 5.3) Pub Date : 2024-05-15 Xinyue Zhang, Jiahua Huang, Jing Zhao, Lisha Li, Fengze Miao, Tingrui Zhang, Zhongjian Chen, Xing Zhou, Zongguang Tai, Quangang Zhu
Background Chronic skin wounds are a leading cause of hospital admissions and reduced life expectancy among older people and individuals with diabetes. Delayed wound healing is often attributed to a series of cellular abnormalities. Matrine, a well-studied component found in Sophora flavescens, is recognized for its anti-inflammatory effects. However, its impact on wound healing still remains uncertain
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Cost of out-of-hospital cardiac arrest survivors compared with matched control groups Resuscitation (IF 6.5) Pub Date : 2024-05-13 Lola Qvist Kristensen, Maurits W. van Tulder, Hans Eiskjær, Lotte Sørensen, Bettina Wulff Risør, Lisa Gregersen Oestergaard
Societal costs of out-of-hospital cardiac arrest (OHCA) survivors may be extensive due to high health care utilization and sick leave. Knowledge of the costs of OHCA survivors may guide decision-makers to prioritize health resources. The aims of the study were to evaluate the costs of OHCA survivors from a societal perspective, and to compare these costs to the costs of individuals with non-cardiac
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Restarting the newborn infant heart Resuscitation (IF 6.5) Pub Date : 2024-05-11 Helen G. Liley, Kristen Haakons
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Enhancing post-arrest prognostication through good outcome prediction Resuscitation (IF 6.5) Pub Date : 2024-05-11 Jonathan Tam, Jonathan Elmer
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Clinical application of digital technology in the use of anterolateral thigh lobulated perforator flaps to repair complex soft tissue defects of the limbs Burns Trauma (IF 5.3) Pub Date : 2024-05-11 Kai-xuan Dong, Ya Zhou, Yao-yu Cheng, Hao-tian Luo, Jia-zhang Duan, Xi Yang, Yong-qing Xu, Sheng Lu, Xiao-qing He
Background It is challenging to repair wide or irregular defects with traditional skin flaps, and anterolateral thigh (ALT) lobulated perforator flaps are an ideal choice for such defects. However, there are many variations in perforators, so good preoperative planning is very important. This study attempted to explore the feasibility and clinical effect of digital technology in the use of ALT lobulated
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Are instructors correctly gauging ventilation competence acquired by course attendees? Resuscitation (IF 6.5) Pub Date : 2024-05-10 Fausto D'Agostino, Felice Eugenio Agrò, Paolo Petrosino, Claudio Ferri, Giuseppe Ristagno
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Factors mediating community race and ethnicity differences in initial shockable rhythm for out-of-hospital cardiac arrests in Texas Resuscitation (IF 6.5) Pub Date : 2024-05-10 Ryan Huebinger, Eric Power, Marina Del Rios, Kevin Schulz, Joseph Gill, Micah Panczyk, Brian McNally, Bentley Bobrow
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The application of deep learning in abdominal trauma diagnosis by CT imaging World J. Emerg. Surg. (IF 8.0) Pub Date : 2024-05-06 Xinru Shen, Yixin Zhou, Xueyu Shi, Shiyun Zhang, Shengwen Ding, Liangliang Ni, Xiaobing Dou, Lin Chen
Abdominal computed tomography (CT) scan is a crucial imaging modality for creating cross-sectional images of the abdominal area, particularly in cases of abdominal trauma, which is commonly encountered in traumatic injuries. However, interpreting CT images is a challenge, especially in emergency. Therefore, we developed a novel deep learning algorithm-based detection method for the initial screening
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Ventilation during cardiopulmonary resuscitation with mechanical chest compressions: How often are two insufflations being given during the 3-second ventilation pauses? Resuscitation (IF 6.5) Pub Date : 2024-05-07 Lotte C. Doeleman, René Boomars, Anja Radstok, Patrick Schober, Quinten Dellaert, Markus W. Hollmann, Rudolph W. Koster, Hans van Schuppen
Mechanical chest compression devices in 30:2 mode provide 3-second pauses to allow for two insufflations. We aimed to determine how often two insufflations are provided in these ventilation pauses, in order to assess if prehospital providers are able to ventilate out-of-hospital cardiac arrest (OHCA) patients successfully during mechanical chest compressions. Data from OHCA cases of the regional ambulance
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Genetic polymorphisms, biomarkers and signaling pathways associated with septic shock: from diagnosis to therapeutic targets Burns Trauma (IF 5.3) Pub Date : 2024-05-07 Mingzheng Wu, Bobin Mi, Liu Liu, Haoli Ma, Cheng Jiang, Shan Jiang, Yulin Li, Yan Zhao
Septic shock is a severe form of sepsis characterized by high global mortality rates and significant heritability. Clinicians have long been perplexed by the differential expression of genes, which poses challenges for early diagnosis and prompt treatment of septic shock. Genetic polymorphisms play crucial roles in determining susceptibility to, mortality from, and the prognosis of septic shock. Research
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Effects of early exercise training following severe burn injury: a randomized controlled trial Burns Trauma (IF 5.3) Pub Date : 2024-05-07 David R Schieffelers, Tianfeng Ru, Haonan Dai, Ziqing Ye, Eric van Breda, Ulrike Van Daele, Weiguo Xie, Jun Wu
Background Despite being a stable component of burn rehabilitation at later stages of recovery, exercise training is not commonly provided during the acute phase of burns. A lack of evidence surrounding its efficacy and safety in severely burned adults has hampered its implementation in acute burn care. The aim of this study was to investigate the capacity of early exercise training to modulate parameters
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Factors associated with family decision-making after pediatric out-of-hospital cardiac arrest Resuscitation (IF 6.5) Pub Date : 2024-05-06 Jessica M. Frelinger, Jonathan M. Tan, Margaret J. Klein, Christopher J.L. Newth, Patrick A. Ross, Meredith C. Winter
This study aims to identify demographic factors, area-based social determinants of health (SDOH), and clinical features associated with medical decision-making after pediatric out-of-hospital cardiac arrest (OHCA). This is a retrospective, exploratory, descriptive analysis of patients < 18 years old admitted to the pediatric intensive care unit (ICU) after OHCA from 2011 to 2022 (n = 217) at an urban
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Which bystander treatment method of foreign body airway obstruction is best? A problem that is stuck on our plate Resuscitation (IF 6.5) Pub Date : 2024-05-06 Byron Drumheller
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Ventilation and oxygenation during CPR: Is the time past to just bag it? Resuscitation (IF 6.5) Pub Date : 2024-05-06 Gerrit J. Noordergraaf, Alyssa Venema
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Histone deacetylase 3-specific inhibitor RGFP966 attenuates oxidative stress and inflammation after traumatic brain injury by activating the Nrf2 pathway Burns Trauma (IF 5.3) Pub Date : 2024-05-05 Lanjuan Xu, Tingting An, Baohui Jia, Qiong Wu, Jinggui Shen, Jie Jin, Jing Liu, Chengjian Li
Background Oxidative stress (OS) and inflammatory reactions play pivotal roles in secondary brain injury after traumatic brain injury (TBI). Histone deacetylase 3 (HDAC3) controls the acetylation of histones and non-histones, which has a significant impact on the central nervous system’s reaction to damage. This research determined the implications of RGFP966, a new and specific inhibitor of HDAC3
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Bag and mask ventilation, an outstanding challenge that we should not leave behind Resuscitation (IF 6.5) Pub Date : 2024-05-03 M García-Martínez, CE Espinosa-Pereiro, A Rodríguez-Núñez
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Do cardiac causes predominate in the etiological classification of out-of-hospital cardiac arrest (OHCA)? Resuscitation (IF 6.5) Pub Date : 2024-05-03 Ching-Yu Chen, Chi-Hsin Chen, Cheng-Yi Fan, Chih-Wei Sung, Edward Pei-Chuan Huang
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LIFEFORCE: Learning initiative for elementary-school fun-oriented resuscitation coaching Europewide. A novel project for resuscitation pre-training of 6–10 years-old schoolchildren in Europe Resuscitation (IF 6.5) Pub Date : 2024-05-03 Andrea Scapigliati, Sevasti Etmektsoglou, Theodoros Kalyvas, Bernd W. Böttiger, Ioannis Kozaris, LIFEFORCE Consortium
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Sebaceous gland organoid engineering Burns Trauma (IF 5.3) Pub Date : 2024-05-02 Yiqiong Liu, Huanhuan Gao, Huating Chen, Shuaifei Ji, Lu Wu, Hongliang Zhang, Yujia Wang, Xiaobing Fu, Xiaoyan Sun
Sebaceous glands (SGs), as holocrine-secreting appendages, lubricate the skin and play a central role in the skin barrier. Large full-thickness skin defects cause overall architecture disruption and SG loss. However, an effective strategy for SG regeneration is lacking. Organoids are 3D multicellular structures that replicate key anatomical and functional characteristics of in vivo tissues and exhibit
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Unlocking the key to increasing survival from out-of-hospital cardiac arrest – 24/7 accessible AEDs Resuscitation (IF 6.5) Pub Date : 2024-04-30 Greg Page, Janet E Bray
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Systematic review and meta-analysis of endovascular therapy versus open surgical repair for the traumatic lower extremity arterial injury World J. Emerg. Surg. (IF 8.0) Pub Date : 2024-04-27 Yuhan Qi, Jiarong Wang, Ding Yuan, Pengchao Duan, Li Hou, Tiehao Wang
For traumatic lower extremity artery injury, it is unclear whether it is better to perform endovascular therapy (ET) or open surgical repair (OSR). This study aimed to compare the clinical outcomes of ET versus OSR for traumatic lower extremity artery injury. The Medline, Embase, and Cochrane Databases were searched for studies. Cohort studies and case series reporting outcomes of ET or OSR were eligible
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Clinicians’ approach to predicting post-cardiac arrest outcomes for patients enrolled in a United States clinical trial Resuscitation (IF 6.5) Pub Date : 2024-04-27 Alexis Steinberg, Yanran Yang, Baruch Fischhoff, Clifton W. Callaway, Patrick Coppler, Romergryko Geocadin, Robert Silbergleit, William J. Meurer, Ramesh Ramakrishnan, Sharon D. Yeatts, Jonathan Elmer
Perceived poor prognosis can lead to withdrawal of life-sustaining therapies (WLST) in patients who might otherwise recover. We characterized clinicians’ approach to post-arrest prognostication in a multicenter clinical trial. Semi-structured interviews were conducted with clinicians who treated a comatose post-cardiac arrest patient enrolled in the Influence of Cooling Duration on Efficacy in Cardiac
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Return to work after out of hospital cardiac arrest, insights from a prospective multicentric French cohort Resuscitation (IF 6.5) Pub Date : 2024-04-27 Nolwen Flajoliet, Jeremy Bourenne, Nathalie Marin, Jonathan Chelly, Jean Baptiste Lascarrou, Cédric Daubin, Wulfran Bougouin, Alain Cariou, Guillaume Geri
About 60 to 70% of out-of-hospital cardiac arrest (OHCA) survivors who worked before cardiac arrest return to work within one year but the precise conditions for this resumption of professional activity remain little known. The objective of this study was to assess components of return to work among OHCA survivors. We used the French national multicentric cohort AfterRosc to include OHCA survivors
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Bystander cardiopulmonary resuscitation differences by sex – The role of arrest recognition Resuscitation (IF 6.5) Pub Date : 2024-04-27 Sonali Munot, Janet E. Bray, Julie Redfern, Adrian Bauman, Simone Marschner, Christopher Semsarian, Alan Robert Denniss, Andrew Coggins, Paul M. Middleton, Garry Jennings, Blake Angell, Saurabh Kumar, Pramesh Kovoor, Matthew Vukasovic, Jason C. Bendall, T. Evens, Clara K. Chow
To assess whether bystander cardiopulmonary resuscitation (CPR) differed by patient sex among bystander-witnessed out-of-hospital cardiac arrests (OHCA). This study is a retrospective analysis of paramedic-attended OHCA in New South Wales (NSW) between January 2017 to December 2019 (restricted to bystander-witnessed cases). Exclusions included OHCA in aged care, medical facilities, with advance care
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Comparing outcomes in patients with exsanguinating injuries: an Eastern Association for the Surgery of Trauma (EAST), multicenter, international trial evaluating prioritization of circulation over intubation (CAB over ABC) World J. Emerg. Surg. (IF 8.0) Pub Date : 2024-04-25 Paula Ferrada, Alberto García, Juan Duchesne, Megan Brenner, Chang Liu, Carlos Ordóñez, Carlos Menegozzo, Juan Carlos Salamea, David Feliciano
Hemorrhage is a major cause of preventable trauma deaths, and the ABC approach is widely used during the primary survey. We hypothesize that prioritizing circulation over intubation (CAB) can improve outcomes in patients with exsanguinating injuries. A prospective observational study involving international trauma centers was conducted. Patients with systolic blood pressure below 90 who were intubated
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Personalized resuscitation using 3D transesophageal echocardiography Resuscitation (IF 6.5) Pub Date : 2024-04-23 Chia-Ching Chen, Diane Lee, Hung-Tsang Yen, Wan-Ching Lien
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Administration and effects of beta blockers and oxandrolone in severely burned adults: a post hoc analysis of the RE-ENERGIZE trial Burns Trauma (IF 5.3) Pub Date : 2024-04-22 Gabriel Hundeshagen, Elisabeth Blears, Viktoria Mertin, Andrew G Day, Alen Palackic, Christian Tapking, Valentin Haug, Ulrich Kneser, Björn Bliesener, Adriana C Panayi, Ariel Aballay, Francois Depret, Christian Stoppe, Daren K Heyland
Background Prospective randomized trials in severely burned children have shown the positive effects of oxandrolone (OX), beta blockers (BB) and a combination of the two (BBOX) on hypermetabolism, catabolism and hyperinflammation short- and long-term post-burn. Although data on severely burned adults are lacking in comparison, BB, OX and BBOX appear to be commonly employed in this patient population
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Biomarkers for neuroprognostication after standard versus extracorporeal cardiopulmonary resuscitation – A sub-analysis of Prague-OHCA study Resuscitation (IF 6.5) Pub Date : 2024-04-20 Helena Brodska, Jana Smalcova, Petra Kavalkova, Danielle R. Lavage, Milan Dusik, Jan Belohlavek, Tomas Drabek
Limited evidence exists for prognostic performance of biomarkers in patients resuscitated from out-of-hospital cardiac arrest (OHCA) with extracorporeal CPR (ECPR). We hypothesized that (1) the time course and (2) prognostic performance of biomarkers might differ between CPR and ECPR in a sub-analysis of Prague-OHCA study. Patients received either CPR ( = 164) or ECPR ( = 92). The primary outcome was
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Evaluating the impact of ELSO guideline adherence on favorable neurological outcomes among patients requiring extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest Resuscitation (IF 6.5) Pub Date : 2024-04-20 Akira Kawauchi, Yohei Okada, Makoto Aoki, Tomoko Ogasawara, Takashi Tagami, Nobuya Kitamura, Mitsunobu Nakamura, SOS-KANTO 2017 Study Group
Selecting the appropriate candidates for extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest (OHCA) is challenging. Previously, the Extracorporeal Life Support Organization (ELSO) guidelines suggested the example of inclusion criteria. However, it is unclear whether patients who meet the inclusion criteria of the ELSO guidelines have more favorable outcomes. We aimed
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The association of recent simulation training and clinical experience of team leaders with cardiopulmonary resuscitation quality during in-hospital cardiac arrest Resuscitation (IF 6.5) Pub Date : 2024-04-20 Johannes Wittig, Bo Løfgren, Rasmus P. Nielsen, Rikke Højbjerg, Kristian Krogh, Hans Kirkegaard, Robert A. Berg, Vinay M. Nadkarni, Kasper G. Lauridsen
We aimed to investigate the association of recent team leader simulation training (<6 months) and years of clinical experience (≥4 years) with chest compression quality during in-hospital cardiac arrest (IHCA). This cohort study of IHCA in four Danish hospitals included cases with data on chest compression quality and team leader characteristics. We assessed the impact of recent simulation training
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From Barriers to Blocks: Overcoming Obstacles to Create Robust Ultrasound-Guided Regional Anesthesia Programs in Emergency Departments Ann. Emerg. Med. (IF 6.2) Pub Date : 2024-04-19 Adrienne Malik MD
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Consensus-Driven Recommendations to Support Physician Pregnancy, Adoption, Surrogacy, Parental Leave, and Lactation in Emergency Medicine Ann. Emerg. Med. (IF 6.2) Pub Date : 2024-04-19 Michelle D. Lall MD MHS, Namita Jayaprakash MB BcH BAO MRCEM, Angela Carrick DO, Bernard P. Chang MD PhD, Nadine T. Himelfarb MD, Ynhi Thomas MD MPH, Matthew L. Wong MD MPH, Valerie Dobiesz MD MPH, Neha P. Raukar MD MS, American College of Emergency Physicians Well-being Committee and the Society of Academic Emergency Medicine’s Academy for Women in Academic Emergency Medicine
The emergency department clinical environment is unique, and guidelines for promoting supportive and equitable workplace cultures ensure success and longevity for pregnant persons and parents in emergency medicine. There is paucity, variability, and dissatisfaction with current parental (historically referred to as maternity and paternity) leave policies. This paper describes the development of consensus-derived
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Goodbye Hartmann trial: a prospective, international, multicenter, observational study on the current use of a surgical procedure developed a century ago World J. Emerg. Surg. (IF 8.0) Pub Date : 2024-04-16 Gennaro Perrone, Mario Giuffrida, Fikri Abu-Zidan, Vitor F. Kruger, Marco Livrini, Gabriele Luciano Petracca, Giorgio Rossi, Antonio Tarasconi, Brian W. C. A. Tian, Elena Bonati, Ricardo Mentz, Federico N. Mazzini, Juan P. Campana, Elisabeth Gasser, Reinhold Kafka-Ritsch, Daniel M. Felsenreich, Christopher Dawoud, Stefan Riss, Carlos Augusto Gomes, Felipe Couto Gomes, Ricardo Alessandro Teixeira Gonzaga
Literature suggests colonic resection and primary anastomosis (RPA) instead of Hartmann’s procedure (HP) for the treatment of left-sided colonic emergencies. We aim to evaluate the surgical options globally used to treat patients with acute left-sided colonic emergencies and the factors that leading to the choice of treatment, comparing HP and RPA. This is a prospective, international, multicenter
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Cerebral edema following cardiac arrest: Are all shades of gray equal? Resuscitation (IF 6.5) Pub Date : 2024-04-16 Rachel Beekman, Emily J. Gilmore
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CT brain perfusion patterns and clinical outcome after successful cardiopulmonary resuscitation: A pilot study Resuscitation (IF 6.5) Pub Date : 2024-04-16 Arsany Hakim, Mattia Branca, Christoph Kurmann, Benedikt Wagner, Manuela Iten, Matthias Hänggi, Franca Wagner
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Cardiac arrest: Treatment is prevention? Resuscitation (IF 6.5) Pub Date : 2024-04-16 Alexis Descatha, Dominique Savary
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Alternative defibrillation strategies: More answers and more questions Resuscitation (IF 6.5) Pub Date : 2024-04-11 Tommaso Scquizzato, Markus B. Skrifvars
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Can small bowel obstruction during pregnancy be treated with conservative management? A review World J. Emerg. Surg. (IF 8.0) Pub Date : 2024-04-10 Xiao Shuang Ling, Wei Cheng Anthony Brian Tian, Goran Augustin, Fausto Catena
Small bowel obstruction can occur during pregnancy, which, if missed, can lead to dire consequences for both the mother and foetus. Management of this condition usually requires surgical intervention. However, only a small number of patients are treated conservatively. The objective was to review the literature to determine the feasibility of conservative management for small bowel obstruction. A systematic
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Norepinephrine or just more epinephrine: Which is the best vasopressor for post-arrest shock? Resuscitation (IF 6.5) Pub Date : 2024-04-10 Nicholas J. Johnson, Ari Moskowitz
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Organ donation after extracorporeal cardiopulmonary resuscitation for refractory out-of-hospital cardiac arrest in a metropolitan cardiac arrest centre in Milan, Italy Resuscitation (IF 6.5) Pub Date : 2024-04-10 Matteo Aldo Bonizzoni, Tommaso Scquizzato, Marina Pieri, Silvia Delrio, Pasquale Nardelli, Alessandro Ortalda, Antonio Dell'Acqua, Anna Mara Scandroglio, ECPR-CARE Collaborators, Otello Giancarlo Turla, Claudia Francescon, Andrea Gambirasio, Tommaso Scaglia
Extracorporeal cardiopulmonary resuscitation (ECPR) may improve survival in refractory out-of-hospital cardiac arrest (OHCA) but also expand the donor pool as these patients often become eligible for organ donation. Our aim is to describe the impact of organ donation in OHCA patients treated with ECPR in a high-volume cardiac arrest centre. Rate of organ donation (primary outcome), organs harvested
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Recalled experience of death: Disinhibition not degeneration in relation to death facilitates inner states of lucid hyperconsciousness with novel cognitive insights Resuscitation (IF 6.5) Pub Date : 2024-04-10 Sam Parnia, Jignesh Patel, Benjamin M. Bloom, Erik Kulstad, Charles D. Deakin, Rebecca Spiegel
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Right Ventricular “Bubble Time” to Identify Patients With Right Ventricular Dysfunction Ann. Emerg. Med. (IF 6.2) Pub Date : 2024-04-10 Allison Cohen MD, Timmy Li PhD, Nicholas Bielawa PA-C, Alexander Nello DO, Allen Gold DO, Margaret Gorlin MS, Mathew Nelson DO, Edward Carlin MD, Daniel Rolston MD MSHPM
We propose a novel method of evaluating right ventricular (RV) dysfunction in the emergency department (ED) using RV “bubble time”—the duration of time bubbles from a saline solution flush are visualized in the RV on echocardiography. The objective was to identify the optimal cutoff value for RV bubble time that differentiates patients with RV dysfunction and report on its diagnostic test characteristics
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Recognizing the fastest growing cause of out-of-hospital cardiac arrest Resuscitation (IF 6.5) Pub Date : 2024-04-09 Aaron M. Orkin, Cameron Dezfulian
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Acne-induced pathological scars: pathophysiology and current treatments Burns Trauma (IF 5.3) Pub Date : 2024-04-06 Wanyu Xu, Dorsa Gholamali Sinaki, Yuchen Tang, Yunsheng Chen, Yixin Zhang, Zheng Zhang
Acne is a common chronic inflammatory dermatosis that can lead to pathological scars (PSs, divided into hypertrophic scars and keloids). These kinds of abnormal scars seriously reduce the quality of life of patients. However, their mechanism is still unclear, resulting in difficult clinical prevention, unstable treatment effects and a high risk of recurrence. Available evidence supports inflammatory
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Follow up of cardiac arrest survivors: Survey of French intensivists practices Resuscitation (IF 6.5) Pub Date : 2024-04-05 Marine Paul, Julie Paquereau, Stéphane Legriel, Alain Cariou
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Outcomes of a proactive first responder system for out-of-hospital cardiac arrests Resuscitation (IF 6.5) Pub Date : 2024-04-04 Adam J.R. Watson, Andrew Cumpstey, Jack Ansell, Martina Brown, Charles D. Deakin
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Good outcome prediction after out-of-hospital cardiac arrest: A prospective multicenter observational study in Korea (the KORHN-PRO registry) Resuscitation (IF 6.5) Pub Date : 2024-04-04 Hyo Jin Bang, Chun Song Youn, Claudio Sandroni, Kyu Nam Park, Byung Kook Lee, Sang Hoon Oh, In Soo Cho, Seung Pill Choi, on behalf of the Korean Hypothermia Network Investigators
To assess the ability of clinical examination, biomarkers, electrophysiology and brain imaging, individually or in combination to predict good neurological outcomes at 6 months after CA. This was a retrospective analysis of the Korean Hypothermia Network Prospective Registry 1.0, which included adult out-of-hospital cardiac arrest (OHCA) patients (≥18 years). Good outcome predictors were defined as
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A retrospective comparison of mechanical cardio-pulmonary ventilation and manual bag valve ventilation in non-traumatic out-of-hospital cardiac arrests: A study from the Belgian cardiac arrest registry Resuscitation (IF 6.5) Pub Date : 2024-04-04 Stefano Malinverni, Stéphan Wilmin, Diane de Longueville, Mathilde Sarnelli, Griet Vermeulen, Mahmoud Kaabour, Marc Van Nuffelen, Ives Hubloue, Simon Scheyltjens, Alessandro Manara, Pierre Mols, Jean-Christophe Richard, Francis Desmet
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Controlled donation after circulatory death in post-cardiac arrest patients: Estimates from a large registry Resuscitation (IF 6.5) Pub Date : 2024-04-04 Marie Renaudier, Yannick Binois, Florence Dumas, Lionel Lamhaut, Frankie Beganton, Daniel Jost, Julien Charpentier, Olivier Lesieur, Eloi Marijon, Xavier Jouven, Alain Cariou, Wulfran Bougouin, Sudden Death Expertise Centre investigators
Controlled donation after circulatory death (cDCD) in post-anoxic brain injury is a valuable source of organs that is still underused in some countries. We assessed the number of potential cDCD donors after out-of-hospital cardiac arrest (OHCA) in Paris and its suburbs and extrapolated the results to the French population. Using the large regional registry of the Great Paris area, we prospectively
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A retrospective, multi-agency ‘target trial emulation’ for the comparison of post-resuscitation epinephrine to norepinephrine Resuscitation (IF 6.5) Pub Date : 2024-04-04 Tanner Smida, Remle P. Crowe, P.S. Martin, James F. Scheidler, Bradley S. Price, James M. Bardes
Epinephrine and norepinephrine are the two most commonly used prehospital vasopressors in the United States. Prior studies have suggested that use of a post-ROSC epinephrine infusion may be associated with increased rearrest and mortality in comparison to use of norepinephrine. We used target trial emulation methodology to compare the rates of rearrest and mortality between the groups of OHCA patients
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Association between survival and number of shocks for pulseless ventricular arrhythmias during pediatric in-hospital cardiac arrest in a national registry Resuscitation (IF 6.5) Pub Date : 2024-04-04 Sarah E. Haskell, Derek Hoyme, M. Bridget Zimmerman, Ron Reeder, Saket Girotra, Tia T. Raymond, Ricardo A. Samson, Marc Berg, Robert A. Berg, Vinay Nadkarni, Dianne L. Atkins, the American Heart Association's Get With The Guidelines®-Resuscitation Investigators
Annually 15,200 children suffer an in-hospital cardiac arrest (IHCA) in the US. Ventricular fibrillation or pulseless ventricular tachycardia (VF/pVT) is the initial rhythm in 10–15% of these arrests. We sought to evaluate the association of number of shocks and early dose escalation with survival for initial VF/pVT in pediatric IHCA. Using 2000–2020 data from the American Heart Association’s (AHA)
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Accuracy of etiological classification of out-of-hospital cardiac arrest: A scoping review Resuscitation (IF 6.5) Pub Date : 2024-04-04 Sedigheh Shaeri, Julie Considine, Katie N. Dainty, Theresa Mariero Olasveengen, Laurie J. Morrison
The Utstein reporting template classifies the etiology of OHCA into “presumed cardiac” and “obvious non-cardiac” or “medical” and “non-medical” categories; however, the accuracy of these classifications is unclear. Ascertaining more accurately the etiology of OHCA is important to tailor advanced life support and identify etiologically consistent patient cohorts for reporting incidence and outcome and
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The effects of bystander interventions for foreign body airway obstruction on survival and neurological outcomes: Findings of the MOCHI registry Resuscitation (IF 6.5) Pub Date : 2024-04-04 Tatsuya Norii, Yutaka Igarashi, Yudai Yoshino, Shunichiro Nakao, MingAn Yang, Danielle Albright, David P. Sklar, Cameron Crandall
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Toxicological profile using mass spectrometry in sudden cardiac arrest survivors admitted to a tertiary centre Resuscitation (IF 6.5) Pub Date : 2024-04-04 Niels Kjær Stampe, Charlotte Glinge, Brian Schou Rasmussen, Priya Bhardwaj, Kristian Linnet, Reza Jabbari, Christian Paludan-Müller, Christian Hassager, Jesper Kjærgaard, Jacob Tfelt-Hansen, Bo Gregers Winkel
There has been no previous thorough toxicological examination of a cohort of patients with resuscitated sudden cardiac arrest. We aimed to determine the qualitative and quantitative drug composition in a resuscitated sudden cardiac arrest population, using forensic toxicology, with focus on prescribed, non-prescribed, and commonly abused drugs. Individuals aged 18–90 years with resuscitated sudden
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Spreading awareness about automated external defibrillators by using location-based mobile game called geocaching Resuscitation (IF 6.5) Pub Date : 2024-04-03 Nino Fijačko, Špela Metličar, Robert Greif
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The experiences of cardiac arrest survivors and their key supporters following cardiac arrest: A systematic review and meta-ethnography Resuscitation (IF 6.5) Pub Date : 2024-03-26 Charlotte Southern, Elizabeth Tutton, Katie N. Dainty, Kate Seers, Nathan A. Pearson, Keith Couper, David R. Ellard, Gavin D. Perkins, Kirstie L. Haywood
To review qualitative studies on the experience of sudden cardiac arrest survival from the perspective of both survivors and their key supporters, including family/close friends. A seven-step meta-ethnography and synthesis of qualitative evidence was undertaken, informed by the Meta-Ethnography Reporting Guidelines (eMERGe). Four major databases were searched (Medline, EMBASE, CINAHL, PsycINFO; January
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Strategic placement of automated external defibrillators at city bicycle-sharing stations: Exploring the potential Resuscitation (IF 6.5) Pub Date : 2024-03-24 Nino Fijačko, Inja Dokl, Špela Metličar, Robert Greif