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Improved outcome with individualised antifibrinolytic therapy: what is the evidence? Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-30 Daniel Bolliger, Marco Ranucci
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Perioperative anaphylaxis and the principle of primum non nocere Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-26 Karen Pedersen, Sarah Green
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Point-of-care testing for tranexamic acid efficacy: a proof-of-concept study in cardiac surgical patients Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-26 Ryogo Yoshii, Yuya Takahashi, Kenichi A. Tanaka, Hidetake Kawajiri, Teiji Sawa, Fumimasa Amaya, Satoru Ogawa
Low-dose tranexamic acid (TXA) has been recently recommended for cardiopulmonary bypass (CPB) to reduce associated complications. Although point-of-care laboratory tests for TXA concentrations are unavailable, a novel TPA-test on the ClotPro® system can measure TXA-induced inhibition of fibrinolysis. We evaluated the performance of the TPA-test and in patients undergoing surgery requiring CPB. Blood
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Postoperative myocardial injury phenotypes and self-reported disability in patients undergoing noncardiac surgery. Comment on Br J Anaesth 2024; 132: 35–44 Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-25 Hui-Zen Hee, Cheng-Wei Lu
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Performance of ChatGPT on a free-response anaesthesia primary examination Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-25 Steven C. Cai, Alpha M.S. Tung, Adam T. Eslick
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Intraoperative hypotension and postoperative outcomes. Response to Br J Anaesth 2024; 132:616–618 Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-25 Filippo D'Amico, Alessandro Pruna, Giovanni Landoni
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Association between EEG metrics and continuous cerebrovascular autoregulation assessment: a scoping review Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-20 Stefan Y. Bögli, Marina S. Cherchi, Erta Beqiri, Peter Smielewski
Cerebrovascular autoregulation is defined as the capacity of cerebral blood vessels to maintain stable cerebral blood flow despite changing blood pressure. It is assessed using the pressure reactivity index (the correlation coefficient between mean arterial blood pressure and intracranial pressure). The objective of this scoping review is to describe the existing evidence concerning the association
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Utilising intraoperative respiratory dynamic features for developing and validating an explainable machine learning model for postoperative pulmonary complications Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-18 Peiyi Li, Shuanliang Gao, Yaqiang Wang, RuiHao Zhou, Guo Chen, Weimin Li, Xuechao Hao, Tao Zhu
Timely detection of modifiable risk factors for postoperative pulmonary complications (PPCs) could inform ventilation strategies that attenuate lung injury. We sought to develop, validate, and internally test machine learning models that use intraoperative respiratory features to predict PPCs. We analysed perioperative data from a cohort comprising patients aged 65 yr and older at an academic medical
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Commonly used antiemetics for prophylaxis of postoperative nausea and vomiting after Caesarean delivery with neuraxial morphine: a network meta-analysis Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-15 Lizhong Wang, Jiayue Huang, Huijing Hu, Xiangyang Chang, Feng Xia
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Closing the gaps: consent and preoperative assessment for children and young people Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-15 Hugo Wellesley, Simon P. Courtman
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Association of preoperative beta-blocker use and cardiac complications after major noncardiac surgery: a prospective cohort study Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-15 Noemi Glarner, Christian Puelacher, Danielle M. Gualandro, Mirjam Pargger, Gabrielle Huré, Silvia Maiorano, Ivo Strebel, Simona Fried, Daniel Bolliger, Luzius A. Steiner, Andreas Lampart, Giovanna Lurati Buse, Edin Mujagic, Didier Lardinois, Christoph Kindler, Lorenz Guerke, Stefan Schaeren, Andreas Mueller, Martin Clauss, Andreas Buser, Angelika Hammerer-Lercher, Christian Mueller, Basel-PMI Investigators
Cardiac complications after major noncardiac surgery are common and associated with high morbidity and mortality. How preoperative use of beta-blockers may impact perioperative cardiac complications remains unclear. In a multicentre prospective cohort study, preoperative beta-blocker use was ascertained in consecutive patients at elevated cardiovascular risk undergoing major noncardiac surgery. Cardiac
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Best practices in cognitive aid design for clinical emergencies. Response to Br J Anaesth 2024; 132: 1007–8 Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-12 Nicola Disma, James Peyton, Francis Veykemans
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The impact of perioperative ketamine or esketamine on the subjective quality of recovery after surgery: a meta-analysis of randomised controlled trials Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-12 Kuo-Chuan Hung, Chia-Li Kao, Chun-Ning Ho, Chung-Hsi Hsing, Ying-Jen Chang, Li-Kai Wang, Shu-Wei Liao, I-Wen Chen
This meta-analysis aimed to evaluate the impact of ketamine/esketamine on postoperative subjective quality of recovery (QoR). MEDLINE, Embase, Cochrane library, and Google Scholar were searched for randomised controlled trials (RCTs) that examined the impacts of perioperative ketamine/esketamine use and postoperative QoR. The primary outcome was subjective QoR (QoR-9, QoR-15, QoR-40) on postoperative
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Utilisation of extended reality for preprocedural planning and education in anaesthesiology: a practical guide for spatial computing Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-11 John E. Rubin, Akshay Shanker, Alexandra B. Berman, Balaji Pandian, Rohan Jotwani
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A call to arms: private equity and the US healthcare system Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-09 Irim Salik
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Antithrombin supplementation attenuates heparin resistance in plasma spiked with Gla-domainless factor Xa S195A in vitro Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-08 Yuko Mishima, Amir L. Butt, Kofi B. Vandyck, Jerrold H. Levy, Kenneth E. Stewart, Kenichi A. Tanaka
Andexanet alfa is a Gla-domainless mutant (S195A) factor Xa (GDXa) approved for acute reversal of oral factor Xa inhibitors. Cardiac surgery patients exposed to andexanet before cardiopulmonary bypass often exhibit severe heparin resistance. There is a paucity of data on the effectiveness and optimal dosage of antithrombin use in this setting. The objective of this study was to evaluate the effect
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Economic analysis of anaesthesia associates and specialty and specialist (SAS) doctors. Comment on Br J Anaesth 2024 Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-06 Jaideep J. Pandit, Stuart B. Hanmer
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Edward Robinson Squibb: an early anaesthesia pioneer Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-05 Alan Jay Schwartz, Jane S. Moon
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Operating room scheduling: knowing and accepting your limits Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-05 Jörg Reutershan, Christian Rupprecht, Thomas Rupprecht
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Should renin–angiotensin system inhibitors be held prior to major surgery? Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-04 Matthieu Legrand
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Outcomes reported in randomised trials of surgical prehabilitation: a scoping review Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-03 Chloé Fleurent-Grégoire, Nicola Burgess, Linda Denehy, Lara Edbrooke, Dominique Engel, Giuseppe Dario Testa, Julio F. Fiore Jr, Daniel I. McIsaac, Stéphanie Chevalier, John Moore, Michael P. Grocott, Robert Copeland, Denny Levett, Celena Scheede-Bergdahl, Chelsia Gillis
Heterogeneity of reported outcomes can impact the certainty of evidence for prehabilitation. The objective of this scoping review was to systematically map outcomes and assessment tools used in trials of surgical prehabilitation. MEDLINE, EMBASE, PsychInfo, Web of Science, CINAHL, and Cochrane were searched in February 2023. Randomised controlled trials of unimodal or multimodal prehabilitation interventions
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Choice of needle and injection rate for fascial plane injection: a randomised controlled study in the soft-embalmed Thiel cadaver Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-03 Ashraf Agweder, Graeme McLeod, Youheng Zeng, Peter Merjavy, Jonathan Womack, Zhihong Huang
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Developmental anaesthesia neurotoxicity in humans: finding the sweet spot? Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-03 Laszlo Vutskits
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Investigation of total 25-hydroxy vitamin D concentrations and postoperative delirium after major cardiac surgery Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-28 Jamie Sparling, Laura Ketigian, Jason Z. Qu, Ariel Mueller, Isabella Turco, Katia Colon, Katherine Adelsberger, Miriam Trigo, Talia Colecchi, Kwame Wiredu, Oluwaseun Akeju, Tina B. McKay
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Advanced chronic kidney disease after surgery and the contribution of acute kidney disease: a national observational cohort study Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-28 Mårten Renberg, Daniel Hertzberg, Claire Rimes-Stigare, Linn Hallqvist, Max Bell
Limited knowledge exists regarding long-term renal outcomes after noncardiac surgery. This study investigated the incidence of, and risk factors for, developing advanced chronic kidney disease (CKD) and major adverse kidney events within 1 yr of surgery in a nationwide cohort. Adults without renal dysfunction before noncardiac surgery in Sweden were included between 2007 and 2013 in this observational
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Under-dosing and over-dosing of neuromuscular blocking drugs and reversal agents. Response to Br J Anaesth 2024; 132: 461–5 Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-27 Kelly Michaelsen, Srdjan Jelacic, T. Andrew Bowdle
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Postoperative opioid prescribing patterns in Ireland: a retrospective multicentre analysis Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-27 Rachel Nolan, Sophia Angelov, Laoise Geoghegan, Mai O'Sullivan, Cian Anderson, Daniel Coffey, Oscar Dennehy, Eoghan Shanley, Gabriella Iohom, Peter Moran, Philip Nolan, Aine O'Gara
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ASGBI trauma committee position statement: a national audit of trauma laparotomy in the UK – an unmet need Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-26 Joanna M. Shepherd, Paul Vulliamy, Max E.R. Marsden, Kate Hancorn, the Association of Surgeons of Great Britain and Ireland Trauma Committee
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Supervision of SAS anaesthetists who are not formally recognised as autonomous. Comment on Br J Anaesth 2024; 132: 867–76 Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-25 Fiona Donald, Ashwini Keshkamat, Sunil Kumar, Kirstin May, Lucy Williams
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Erratum to ‘Association between self-reported functional capacity and general postoperative complications: analysis of predefined outcomes of the MET-REPAIR international cohort study’ (Br J Anaesth 2024; 132: 811–4) Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-23 Sebastian Roth, René M'Pembele, Johannes Nienhaus, Eckhard Mauermann, Daniela Ionescu, Wojciech Szczeklik, Stefan De Hert, Miodrag Filipovic, Beatrice Beck-Schimmer, Savino Spadaro, Purificación Matute, Daniel Bolliger, Sanem C. Turhan, Judith van Waes, Filipa Lagarto, Kassiani Theodoraki, Anil Gupta, Hans-Jörg Gillmann, Luca Guzzetti, Katarzyna Kotfis, Hinnerk Wulf, Jan Larmann, Dan Corneci, Frédérique
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Pain after combat injury in male UK military personnel deployed to Afghanistan Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-23 Jan Vollert, Alexander Kumar, Emma C. Coady, Paul Cullinan, Daniel Dyball, Nicola T. Fear, Zoe Gan, Eleanor F. Miller, Stefan Sprinckmoller, Suzie Schofield, Alexander Bennett, Anthony M.J. Bull, Christopher J. Boos, Andrew S.C. Rice, Harriet I. Kemp, the ADVANCE Study
Chronic pain after injury poses a serious health burden. As a result of advances in medical technology, ever more military personnel survive severe combat injuries, but long-term pain outcomes are unknown. We aimed to assess rates of pain in a representative sample of UK military personnel with and without combat injuries. We used data from the ADVANCE cohort study (ISRCTN57285353). Individuals deployed
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International consensus is needed on a core outcome set to advance the evidence of best practice in cancer prehabilitation services and research Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-23 Anna M. Myers, Rachael C. Barlow, Gabriele Baldini, Anna M. Campbell, Franco Carli, Esther J. Carr, Tom Collyer, Gerard Danjoux, June F. Davis, Linda Denehy, James Durrand, Chelsia Gillis, Diana M. Greenfield, Stuart P. Griffiths, Mike Grocott, Liam Humphreys, Sandy Jack, Carol Keen, Denny Z.H. Levett, Zoe Merchant, John Moore, Susan Moug, William Ricketts, Daniel Santa Mina, John M. Saxton, Clare
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Metaraminol-induced coronary vasospasm masquerading as ST-elevation myocardial infarction during general anaesthesia Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-23 Joshua G. Kovoor, Daniel Gorman, Neil Warwick, Gopal Sivagangabalan, Pramesh Kovoor
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Critical care utilisation for patients receiving chimeric antigen receptor (CAR) T cell therapy in the UK Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-22 Tasneem Pirani, Anthony Wilson, David Brealey, Ryan Low, Suzanne O'Neill, Jenny Le, Shaman Jhanji, Mansoor N. Bangash, Amrith Mathew, Christopher Wright, Anne-Louise Latif, David Irvine, Vidya Kasipandian, Neeraj Singh, Rohit Saha, Victoria Metaxa
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Limitations of the consent process in paediatric anaesthesia: the Death during Anaesthesia – Risk and Explanation (DARE) audit Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-20 Tom C. Lyne, Harry D. Everton, Lisa Barkley, Benjamin J. Blaise
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Airway triage: a novel application-based method for airway assessment and risk stratification Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-19 Johannes M. Huitink
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Examining disparities in regional anaesthesia and pain medicine Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-19 Uchenna O. Umeh
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Modelling the economic constraints and consequences of Anaesthesia Associate expansion in the UK National Health Service. Response by the Association of Anaesthetists SAS Committee to Br J Anaesth 2024; 132: 867–76 Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-19 Robert J. Fleming, Emma C.E. Wain
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Modelling the economic constraints and consequences of Anaesthesia Associate expansion in the UK. Response from the Association of Anaesthetists Trainee Committee to Br J Anaesth 2024; 132: 867–76 Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-19 Ben Evans, Stuart Edwardson, representing the Association of Anaesthetists Trainee Committee
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Predictive and protective factors for failing first pass intubation in prehospital rapid sequence intubation: an aetiology and risk systematic review with meta-analysis Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-19 Clare Hayes-Bradley, Michael McCreery, Ashleigh Delorenzo, Jason Bendall, Anthony Lewis, Kelly-Ann Bowles
Prehospital rapid sequence intubation first pass success rates vary between 59% and 98%. Patient morbidity is associated with repeat intubation attempts. Understanding what influences first pass success can guide improvements in practice. We performed an aetiology and risk systematic review to answer the research question ‘what factors are associated with success or failure at first attempt laryngoscopy
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Epidemiology of perioperative anaphylaxis in France in 2017–2018: the 11th GERAP survey Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-16 Charles Tacquard, Julien Serrier, Simon Viville, Anca-Mirela Chiriac, Sébastien Franchina, Aurélie Gouel-Cheron, Antoine Giraudon, Morgan Le Guen, Diane Le Quang, Jean-Marc Malinovsky, Nadine Petitpain, Pascal Demoly, Paul M. Mertes, for the GERAP study group, Morisset Martine, Husser Solène, Huyn Vinh An, Perquin Mélanie, Lakkis-Castelain Florence, Feesenmeyer Christine, Pellerin Christelle, Bordes-Demolis
Perioperative anaphylaxis is rare but is associated with significant morbidity. This complication has been well described in France by the GERAP (Groupe d'Etude des Réactions Anaphylactiques Périopératoires), a network focused on its study. The epidemiology of perioperative anaphylaxis is evolving, influenced by environmental factors and clinical practice. The aim of this study was to update the epidemiology
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Monitoring of cerebral blood flow autoregulation: physiologic basis, measurement, and clinical implications Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-12 Eric L. Vu, Charles H. Brown IV, Kenneth M. Brady, Charles W. Hogue
Cerebral blood flow (CBF) autoregulation is the physiologic process whereby blood supply to the brain is kept constant over a range of cerebral perfusion pressures ensuring a constant supply of metabolic substrate. Clinical methods for monitoring CBF autoregulation were first developed for neurocritically ill patients and have been extended to surgical patients. These methods are based on measuring
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Intraoperative cell salvage: a survey of UK practice Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-12 Manisha M. Kumar, Falguni Choksey, Alister Jones, Craig Carroll, Bella Brownhill, Elmarie Cairns, Joanne Bark, Kairen Coffey, Louise Webster, Louisa Wood, Malcolm Chambers, Sarah Haynes, Sheena Gormley
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Influence of nitrous oxide added to general anaesthesia on postoperative mortality and morbidity: a systematic review and meta-analysis Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-11 Jasper M. Kampman, Kim Y.Q. Plasmans, Jeroen Hermanides, Markus W. Hollmann, Sjoerd Repping, Nicolaas H. Sperna Weiland
Nitrous oxide (NO) is a common adjuvant to general anaesthesia. It is also a potent greenhouse gas and causes ozone depletion. We sought to quantify the influence of NO as an adjuvant to general anaesthesia on postoperative patient outcomes. We searched Medline, EMBASE, and Cochrane Central for works published from inception to July 6, 2023. RCTs comparing general anaesthesia with or without NO were
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Therapeutic efficacy of intravenous lidocaine infusion compared with thoracic epidural analgesia in major abdominal surgery. Response to Br J Anaesth 2023; 132: 625–6 Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-06 Fabian D. Casas-Arroyave, Susana C. Osorno-Upegui, Mario A. Zamudio-Burbano
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Dose-dependent relationship between SGLT2 inhibitor hold time and risk for postoperative anion gap acidosis. Response to Br J Anaesth 2023; 131: 682–686. Br J Anaesth 2024; 132: 822–3 Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-05 Benjamin Steinhorn
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Regional anaesthesia truncal blocks for acute postoperative pain and recovery. Response to Br J Anaesth 2024; 132: 1166–7 Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-05 Aisling Ní Eochagáin, Donal J. Buggy
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Celebrating the state of the art and innovations in regional anaesthesia in the British Journal of Anaesthesia Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-05 David W. Hewson, Jenny Ferry, Alan J.R. Macfarlane
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Too loud to hear myself think: deleterious effects of noise in the operating room Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-05 Joyce A. Wahr, James H. Abernathy III
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Intraoperative hypotension is not associated with reduced atrial fibrillation or hospital length of stay. Response to Br J Anaesth 2023; 132: 181–3 Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-05 Filippo D'Amico, Giovanni Landoni
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Comparison of tracheal intubation conditions between the operating room and intensive care unit: impact of universal videolaryngoscopy Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-05 Manuel Taboada, Agustín Cariñena, Manuela De Miguel, Fátima García, Sara Alonso, Rocío Iraburu, Laura Barreiro, Laura Dos Santos, Ana Tubio, María Diaz-Vieito, Julián Álvarez, Teresa Seoane-Pillado
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Ward monitoring 4.0: real-time metabolic insights from continuous glucose monitoring into perioperative organ dysfunction Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-05 Henrike Janssen, Shaman Jhanji, Nick S. Oliver, Gareth L. Ackland, for the GlucoVITAL Investigators, Marta Korbonits, Sian Henson, Joyce Yeung, Rupert Pearse, Ben Shelley, Louise Hiller, Peter Jacob, James Noblet, Monica Jefford, Ana Gutierrez del Arroyo, Abeer Samman, Saja Alharbi, Sanjali Ahuja, Priya Dias
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Melanin bias in pulse oximetry explained by light source spectral bandwidth Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-05 Andrew Bierman, Kevin Benner, Mark S. Rea
Pulse oximetry uses noninvasive optical measurements of light transmission from each of two sources through vascularised living tissue over the cardiac cycle (SpO). From those measurements, the relative amount of oxygenated haemoglobin (SaO) in circulating blood can be deduced. Recent reports have shown that, compared with SaO measurements from blood samples, SpO measurements are biased erroneously
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Artificial intelligence for ultrasound scanning in regional anaesthesia: a scoping review of the evidence from multiple disciplines Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-05 James S. Bowness, David Metcalfe, Kariem El-Boghdadly, Neal Thurley, Megan Morecroft, Thomas Hartley, Joanna Krawczyk, J. Alison Noble, Helen Higham
Artificial intelligence (AI) for ultrasound scanning in regional anaesthesia is a rapidly developing interdisciplinary field. There is a risk that work could be undertaken in parallel by different elements of the community but with a lack of knowledge transfer between disciplines, leading to repetition and diverging methodologies. This scoping review aimed to identify and map the available literature
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Research priorities in regional anaesthesia: an international Delphi study Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-05 Jenny Ferry, Owen Lewis, James Lloyd, Kariem El-Boghdadly, Rachel Kearns, Eric Albrecht, Fernando Altermatt, Balakrishnan Ashokka, Amany E. Ayad, Ezzat S. Aziz, Lutful Aziz, Balavenkatasubramanian Jagannathan, Noreddine Bouarroudj, Ki Jinn Chin, Alain Delbos, Alex de Gracia, Vivian H.Y. Ip, Kwesi Kwofie, Sebastian Layera, Clara A. Lobo, Mohammed Mohammed, Eleni Moka, Milena Moreno, Bethan Morgan, Arthur
Regional anaesthesia use is growing worldwide, and there is an increasing emphasis on research in regional anaesthesia to improve patient outcomes. However, priorities for future study remain unclear. We therefore conducted an international research prioritisation exercise, setting the agenda for future investigators and funding bodies. We invited members of specialist regional anaesthesia societies
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Regional anaesthesia education for consultants and specialists in the UK: a mixed-methods analysis Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-05 Xiaoxi Zhang, Ross J. Vanstone, Lloyd Turbitt, Simeon West, Eoin Harty
Regional anaesthesia plays an important role in perioperative care, but gaps in proficiency persist among consultants and specialists. This study aimed to assess confidence levels in performing Plan A blocks among this cohort and to examine the barriers and facilitators influencing regional anaesthesia education. Utilising a mixed-methods design, we performed a quantitative survey to gauge self-reported
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Remimazolam versus propofol for sedation in gastrointestinal endoscopic procedures: a systematic review and meta-analysis Br. J. Anaesth. (IF 9.8) Pub Date : 2024-03-04 Eduardo Cerchi Barbosa, Paula Arruda Espírito Santo, Stefano Baraldo, Gilmara Coelho Meine
Propofol has a favourable efficacy profile in gastrointestinal endoscopic procedures, however adverse events remain frequent. Emerging evidence supports remimazolam use in gastrointestinal endoscopy. This systematic review and meta-analysis compares remimazolam and propofol, both combined with a short-acting opioid, for sedation of adults in gastrointestinal endoscopy. We searched MEDLINE, Embase,
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Associations between acute pain after vaginal delivery and postpartum opioid prescription fills: a retrospective case-controlled study Br. J. Anaesth. (IF 9.8) Pub Date : 2024-02-29 Grace Lim, Lingshu Xue, Julie M. Donohue, Stefanie Junker, J. Deanna Wilson, Brian Suffoletto, Michael J. Lynch, Maria L. Pacella-LaBarbara, Chung-Chou H. Chang, Elizabeth Krans, Marian Jarlenski
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Assessment of sedation by automated pupillometry in critically ill patients: a prospective observational study Br. J. Anaesth. (IF 9.8) Pub Date : 2024-02-29 Lin Shi, Dan-Ni Jin, Xia-Jing Cao, Hong Liu, Wen-Jie Gu, Mao Zhang, Qin Lu
Quantitative measurement of pupil change has not been assessed against the Richmond Agitation and Sedation Scale (RASS) and spectral edge frequency (SEF) during sedation. The aim of this study was to evaluate pupillometry against these measures in sedated critically ill adult patients. In ventilated and sedated patients, pupillary variables were measured by automated pupillometry at each RASS level