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成果及论文

7. R. A. Faulkner, Y. Yang, J. Tsien, T. Qin, R. A. DeBose- Boyd. Direct binding to sterols accelerates endoplasmic reticulum- associated degradation of HMG CoA reductase. PNAS 2024, 121, e2318822121. https://www.pnas.org/doi/epdf/10.1073/pnas.2318822121

6. Y. Yang, J. Tsien, R. Dykstra, S. Chen, J. B. Wang, R. R. Merchant, J. M. E. Hughes, B. K. Peters, O. Gutierrez, T. Qin. Programmable late-stage functionalization of bridge-substituted bicyclo[1.1.1]pentane bis-boronates. Nat. Chem. 2023, 16, 285–293. https://www.nature.com/articles/s41557-023-01342-7

5. Y. Yang, J. Tsien, J. M. E. Hughes, B. K. Peters, R. R. Merchant, T. Qin. An intramolecular coupling approach to alkyl bioisosteres for the synthesis of multisubstituted bicycloalkyl boronates. Nat. Chem. 2021, 13, 950–955. https://doi.org/10.1038/s41557-021-00786-z

4. Y. Yang, J. Tsien, A. David, J. M. E. Hughes, R. R. Merchant, T. Qin. Practical and modular construction of C(sp3)-rich alkyl boron compounds. J. Am. Chem. Soc. 2021, 143, 471–480. https://pubs.acs.org/doi/epdf/10.1021/jacs.0c11964

3. Y. Yang, L. Eberle, F. F. Mulks, J. F. Wunsch, M. Zimmer, F. Rominger, M. Rudolph, A. S. K. Hashmi. Trans influence of ligands on the oxidation of gold(I) complexes. J. Am. Chem. Soc. 2019, 141, 17414–17420. https://pubs.acs.org/doi/epdf/10.1021/jacs.9b09363

2. Y. Yang, P. Antoni, M. Zimmer, K. Sekine, F. Mulks, L. Hu, L. Zhang, M. Rudolph, F. Rominger, A. S. K. Hashmi. Dual gold/silver catalysis involving alkynylgold(III) intermediates formed by oxidative addition and silver-catalyzed C–H activation for the direct alkynylation of cyclopropenes. Angew. Chem. Int. Ed. 2019, 58, 5129–5133. (very important paper) https://onlinelibrary.wiley.com/doi/epdf/10.1002/anie.201812577

1. Y. Yang, J. Schießl, S. Zallouz, V. Göker, J. Gross, M. Rudolph, F. Rominger, A. S. K. Hashmi. Gold-catalyzed C(sp2)–C(sp) coupling by alkynylation through oxidative addition of bromoalkynes. Chem. Eur. J. 2019, 25,96249628. https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/chem.201902213