Since starting my independent work at Changzhou University, the research projects in my group have mainly focused on:

(1) Catalytic Enantioselective Synthesis of Chiral Fluorenes

For recent publications through a desymmetrizing strategy：

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Feng Jiang, Y. Zhao*, W. Guo* et al., Org. Lett., 2023, 25, 6006

Selected example with potential utilities：

★As a deep-blue emitter used in OLEDs

★As a reversible pH-responsive probe:

★As circularly polarized luminescence(CPL) emitters:

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Ying Zhou, W. Guo* et al., Org. Lett., 2024, 26, 877

★As a versatile chiral fluorenes building block

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T. Ou, X. Wang*, W. Guo* et al., Eur. J. Org. Chem., 2024, e202400795 (the invited review on this research subject);

★ We can provide the following chiral fluorene samples free of charge for research purposes:

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(2) （a）Organocatalyzed Asymmetric Reaction Involving (Sulfur) Ylide or Free Carbene

        (b)  Explore Novel Bioorthogonal Reactions using Sulfur Ylide as the Probe

For recent publications:

X. Yue, S. Li, L. Song*, Y. Zhao*, W. Guo* et al., Org. Front. Chem., 2024, 11, 4084;

X. Yue, Y. Zhao*, W. Guo* et al., Chem. Commun., 2023, 59, 6363; 

Y. Zhou, W. Guo* et al., Chem. Commun., 2023, 59, 1193;

Y. Zhou, W. Guo* et al., Tetrahedron Lett., 2023, 122, 154496;

W. Guo*, Y. Zhou, J. Sun* et al., Chem. Sci., 2023, 14, 843; 

W. Guo*, F. Jiang, S. Li, J. Sun*, Chem. Sci., 2022, 13, 11648; 

W. Guo, H. Huang*, J. Sun* et al., Chem. Sci., 2021,12, 11191; 

(3) Development of New Organocatalyst or Ligand and Their Utilities in Asymmetric Reactions

This subject is mainly focused on developing novel chiral organic Lewis acids and their utilizations in asymmetic catalysis.