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成果及论文

研究型论文(Original Research):

[第一作者,First Author]

1. circPARD3 drives malignant progression and chemoresistance of laryngeal squamous cell carcinoma by inhibiting autophagy through the PRKCI-Akt-mTOR pathway, Molecular Cancer, 2020, 19(1):166 (大类TOP1区, IF=41.444, 第一作者)

2. Promoter Methylation-Regulated miR-145-5p Inhibits Laryngeal Squamous Cell Carcinoma Progression by Targeting FSCN1, Molecular Therapy, 2019, 27(2): 365-379 (大类TOP1区, IF=11.454, ESI高被引, 第一作者)

3. Targeting SKA3 suppresses the proliferation and chemoresistance of laryngeal squamous cell carcinoma via impairing PLK1-AKT axis-mediated glycolysis, Cell Death & Disease, 2020, 11(10): 919 (大类2区, IF=8.469, 第一作者)

4. Identification of miR-145-5p-centered competing endogenous RNA network in laryngeal squamous cell carcinoma, Proteomics, 2019, 6(21-22): e1900020 (大类2区, IF=3.984, 第一作者)

5. Mass Spectrometric Analysis Identifies AIMP1 and LTA4H as FSCN1 Binding Proteins in Laryngeal Squamous Cell Carcinoma, Proteomics, 2019, 19(21-22): e1900059 (大类2区, IF=3.984, 第一作者)

6. MicroRNA-204-5p inhibits invasion and metastasis of laryngeal squamous cell carcinoma by suppressing forkhead box C1, Journal of Cancer, 2017, 8(12): 2356-2368 (大类3区, IF=4.207,第一作者)

7. Fascin-1, Ezrin and Paxillin Contribute to the Malignant Progression and Are Predictors of Clinical Prognosis in Laryngeal Squamous Cell Carcinoma, Plos One, 2012, 7(11): e50710 (大类3区, IF=3.240, 第一作者)

8. Potential biomarkers and their regulatory relationships in laryngeal squamous cell carcinoma with lymph node metastasis revealed by integrating mRNA, microRNA and long non-coding RNA profiles, International Journal Of Clinical And Experimental Pathology, 2016, 9(5): 5103-5116 (大类4区, IF=1.706, 第一作者)

[最终责任通讯, Corresponding Author]

9. Circular RNA circCORO1C promotes laryngeal squamous cell carcinoma progression by modulating the let-7c-5p/ PBX3 axis, Molecular Cancer, 2020, 19(1): 99 (大类TOP1区, IF=41.444, 通讯作者)

10. miR-1207-5p suppresses laryngeal squamous cell carcinoma progression by downregulating SKA3 and inhibiting epithelial-mesenchymal transition, Molecular Therapy-Oncolytics, 2021, 19(22):152-165. (大类2区, IF=7.2, 通讯作者)

11. Petroleum extract of Farfarae Flos alleviates nasal symptoms by regulating the Th1-Th2 cytokine balance in a mouse model of Allergic Rhinitis, International journal of medical sciences, 2021, 18(2): 555-563 (大类3区, IF=3.738, 通讯作者)

12. Mass spectrometry-based proteomic analysis of FSCN1-interacting proteins in laryngeal squamous cell carcinoma cells, IUBMB Life, 2019, 71(11): 1771-1784 (大类3区, IF=3.885, 通讯作者)

[共同通讯, Co-Corresponding Author]

13. Epidemiological Analysis of 1234 Cases of Laryngeal Cancer in Shanxi Province, China, Cancer control, 2021, 28:10732748211041236.(大类3区, IF=3.302, 共同通讯) 

14. Alterations of bacterial communities of vocal cord mucous membrane increases the risk for glottic laryngeal squamous cell carcinoma, Journal of cancer, 2021, 12(13): 4049-4063 (大类3区, IF=4.207, 共同通讯) 

15. Serum Exosomal miR-941 as a promising Oncogenic Biomarker for Laryngeal Squamous Cell Carcinoma, Journal of Cancer, 2020, 11(18): 5329-5344 (大类3区, IF=4.207,共通作者)

16. miR-424-5p Promotes Proliferation, Migration and Invasion of Laryngeal Squamous Cell Carcinoma, Oncotargets And Therapy, 2019, 12: 10441-10453 (大类3区, IF=4.147, 共通作者)

17. Astragali radix total flavonoid synergizes cisplatin to inhibit proliferation and enhances the chemosensitivity of laryngeal squamous cell carcinoma, Rsc Advances, 2019, 9(42): 24471-24482 (大类3区, IF=3.361, 共通作者)

18. Whole-Transcriptome Analysis of CD133+CD44+ Cancer Stem Cells Derived from Human Laryngeal Squamous Cell Carcinoma Cells, Cellular Physiology And Biochemistry, 2018, 47(4): 1696-1710 (大类2区, IF=5.5, 共通作者)

[共同第一作者, Co-First Author]

19. AlloDriver: a method for the identification and analysis of cancer driver targets, Nucleic Acids Research, 2019, 47(W1): W315-W321 (大类TOP1区, IF=16.971, 共同第一作者)

20. Enhanced endosomal escape by photothermal activation for improved small interfering RNA delivery and antitumor effect, International Journal of Nanomedicine, 2018, 13: 4333-4344 (大类2区, IF=6.4, 共同第一作者)

21. Identification and characterization of CD133+CD44+ cancer stem cells from human laryngeal squamous cell carcinoma cell lines, Journal of Cancer, 2017, 8(3): 497-506 (大类3区, IF=4.207, 共同第一作者)

22. Potential key molecular correlations in laryngeal squamous cell carcinoma revealed by integrated analysis of mRNA, miRNA and lncRNA microarray profiles, Neoplasma, 2016, 63(6): 888-900 (大类4区, IF=2.575, 共同第一作者)

23.  Hsa-miR-301a-3p Acts as an Oncogene in Laryngeal Squamous Cell Carcinoma via Target Regulation of Smad4, Journal of Cancer, 2015, 6(12): 1260-1275 (大类3区, IF=4.207, 共同第一作者)

[其他位列作者, Co-Author]

24. LncRNA REG1CP promotes tumorigenesis through an enhancer complex to recruit FANCJ helicase for REG3A transcription, Nature Communications, 2019, 10(1): 5334(大类TOP1区, IF=14.919, 第六作者)

25. c-Myc inactivation of p53 through the pan-cancer lncRNA MILIP drives cancer pathogenesis, Nature communications, 2020, 11(1): 4980 (大类TOP1区, IF=14.919, 第六作者) 


综述性论文(Review):

[通讯或共通讯, Co/Corresponding Author]

26. Application of the CRISPR/Cas9-based gene editing technique in basic research, diagnosis, and therapy of cancer, Molecular cancer, 2021, 20(1): 126 (大类TOP1区, IF=41.444, 共同通讯)

27. Fascin actin-bundling protein 1 in human cancer: Promising biomarker or therapeutic target?, Molecular therapy-oncolytics, 2021, 20:240-264 (大类2区, IF=7.2,通讯作者)

28. Crosstalk between RNA m6A modification and non-coding RNA contributes to cancer growth and progression, Molecular Therapy: Nucleic Acid, 2020; 22:62-71 (大类1区, TOP1区, IF=8.886, 通讯作者) 

29. Non-coding RNAs in drug resistance of head and neck cancers: A review, Biomedicine & Pharmacotherapy, 2020, 127(2020): 110231 (大类2区, IF=6.529, 通讯作者)

30. Effect of HPV infection on the occurrence and development of laryngeal cancer: a review, Journal of Cancer, 2019, 10(19): 4455-4462 (大类3区, IF=4.207, 通讯作者)

31. Regulatory role and mechanism of m6A RNA modification in human metabolic diseases, Molecular Therapy - Oncolytics, 2021 , doi.org/10.1016/j.omto.2021.05.003 (大类分区2区, IF=7.2, 共同通讯)

32. Tumor microenvironment and immune-related therapies of Head and neck squamous cell carcinoma, Molecular therapy-oncolytics, 2021, 20:342-351 (大类2区, IF=7.2, 共同通讯)


知识产权(Patent & Copyright):

1. 第一发明人, 一种细胞平板克隆形成图像采集仪, 2016.03.30, 中国, ZL 201520998317.9

2. 第一发明人, 一种抑制FOXC1基因表达的siRNA及其应用, 2015.07.08, 中国, ZL 201310651571.7

3. 第一发明人, 人微小RNA启动子甲基化扩增及测序引物及其应用, 2015.06.10, 中国, ZL 201310359969.3

4. 第一发明人, 一种针对人fascin-1基因的siRNA及其应用, 2015.04.22, 中国, ZL 201310004333.7

5. 第一发明人, 一种耳鼻咽喉头颈外科专用颞骨及头部解剖训练台, 2018.04.10, 中国, ZL 201611056422.6

6. 第一发明人, 一种耳鼻咽喉头颈外科专用颞骨及头部解剖训练台, 2017.09.29, 中国, ZL 201621277012.X

7. 第一发明人, 耳鼻咽喉头颈外科专用颞骨及头颈部解剖训练台, 2017.03.08, 中国, ZL 201630575793.X

8. 第一发明人, 用于火棉胶包埋全喉大体标本专用的包埋底盒, 2012.04.18, 中国, ZL 201010579358.6

9. 第一发明人, 智能正压恒温仿生式全自动鼻腔冲洗治疗仪, 2008.12.03, 中国, ZL 200720104850.1

10. 第二发明人, 可调节的琼脂糖凝胶回收切胶器, 2019.10.18, 中国, ZL 201930041826.6

11. 第二发明人, 一种尸头解剖固定架, 2019.02.19, 中国, ZL 201820029259.2

12. 第二发明人, 尸头解剖固定架, 2018.06.19, 中国, ZL 201830007713.X

13. 第二发明人, 一种Hsa-miR-145-5p试剂盒及其成熟体模拟物的应用, 2016.09.09, 中国, ZL 201310408755.0

14. 第二发明人, 一种带UV紫外线灯的离心管架, 2016.08.31, 中国, ZL 201620339275.2

15. 第二发明人, 全自动鼻腔冲洗治疗仪, 2014.12.31, 中国, ZL 201430176954.9

16. 第三发明人, 一种摇床, 2019.11.22, 中国, ZL 201920109376.4

17. 第三发明人, 一种可调节的琼脂糖凝胶回收切胶器, 2019.10.18, 中国, ZL 201920124174.7

18. 第四发明人, 一种慢病毒单质粒体内生物素化载体及制备方法, 2019.11.19, 中国, ZL 201610928951.4

19. 第四发明人, 细胞划痕实验辅助装置, 2019.11.05, 中国, ZL 201920134722.4

20. 第四发明人, 摇床, 2019.06.21, 中国, ZL 201930036349.4

21. 第四发明人, 一次性外耳道硅胶冲洗管, 2013.04.03, 中国, ZL201220484661.2

22. 第六发明人, 戴维氏开口器的软腭牵拉装置, 2015.04.29, 中国, ZL201310329412.5

23. 第六发明人, 戴维氏开口器的软腭牵拉装置, 2014.01.15, 中国, ZL201320464888.5

24. 第一权利人, 科研业务综合管理系统V5.0, 2016SR107789, 原始取得, 全部权利, 2016.05.17

25. 第一权利人, 科研综合业务云智慧管理系统, 2019SR0262022, 原始取得, 全部权利, 2019.03.19

26. 第二权利人, 实验室实验技能在线考试管理系统, 2019SR0947048, 原始取得, 全部权利, 2019.09.11

27. 第二权利人, 头颈肿瘤转录组与随访数据管理系统V1.0, 2019SR0807557, 原始取得, 全部权利, 2019.08.02

28. 第二权利人, 耳鼻咽喉-头颈外科患者随访系统V3.0, 2013SR049554, 原始取得, 全部权利, 2013.05.24


科研奖励(Scientific Reward):

1. 第二获奖人, 喉鳞癌转录组差异网络构建与关键生物学功能调控机制研究, 山西省科学技术奖自然科学类一等奖, 2019.03

2. 省级优秀博士学位论文, 2015.01.21

3. 省级优秀硕士学位论文, 2011.03

4. 第一获奖人, 山西省优秀学术论文二等奖, 2016.08

5. 第一获奖人,  山西省优秀学术论文二等奖, 2016.08

6. 第二获奖人,  北京发明创新大赛铜奖, 2015.04

7. 第一获奖人,  北京发明创新大赛铜奖, 2015.04

8. 第一获奖人,  中央国家机关团工委首届先锋青年创新创意大赛一等奖, 2014.12

9. 第一获奖人,  第八届国际发明展览会“发明创业奖.项目奖”铜奖, 2014.11

10. 第一获奖人,  上海发明创新大赛二等奖, 2014.07