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成果及论文

一、期刊论文

1. Lin Huang, Wei Chen*, et al. Rolling Chain Amplification Based Signal-Enhanced Electrochemical Aptasensor for Ultrasensitive Detection of Ochratoxin A, Analytical Chemistry, 2013, 85, 10842-10849;

2. Wei Chen, Dinghua Xu, Liqiang Liu, et al. Ultrasensitive Detection of Trace Protein by Western Blot Based on POL Y -Quantum Dot Probes, Analytical Chemistry, 2009, 81, 9194-9198;

3. Li Y ao, Yingwang Y e, Wei Chen*, et al. In Vitro Isothermal Nucleic Acid Amplification Assisted Surface-Enhanced Raman Spectroscopic for Ultrasensitive Detection of Vibrio  parahaemolyticus, Analytical Chemistry, 2017, 89, 9775-9780;

4. DongqingQiao, Jianguo Xu, Wei Chen*, et al. Highly Simple and Sensitive Molecular Amplification-Integrated Fluorescence Anisotropy for Rapid and On-Site Identification of Adulterated Beef, Analytical Chemistry, 2018, 90, 7171-7175;

5. Wei Chen, Chao Yan, Lin Cheng, et al. An ultrasensitive signal-on electrochemical aptasensor for ochratoxin A determination based on DNA controlled layer-by-layer assembly of dual gold nanoparticle conjugates, Biosensors & Bioelectronics, 2018, 117, 845-851;

6. Zhanlong Mei, Wei Qu, Wei Chen*, et al. One-step signal amplified lateral flow strip biosensor for ultrasensitive and on-site detection of bisphenol A (BPA) in aqueous samples, Biosensors & Bioelectronics, 2013, 49, 457-461;

7. Mengya Zhu Ying Wang, Wei Chen*, etal. Ultrasensitive detection of mercury with a novel one-step signal amplified lateral flow strip based on gold nanoparticle-labeled ssDNA recognition and enhancement probes, Biosensors & Bioelectronics, 2014, 61, 14-20;

8. Li Y ao, Jun Teng, Wei Chen*, et al. MWCNTs based high sensitive lateral flow strip biosensor for rapid determination of aqueous mercury ions, Biosensors & Bioelectronics, 2016, 85, 331-336.

10. Jingjing Wu, Huaqin Chu, Wei Chen*, et al. Ultrasensitive one-step rapid detection of ochratoxin A by the folding-based electrochemical aptasensor, Analytica Chimica Acta, 2012, 753, 27-31;

11. Wei Chen, Jun Teng, Li Yao, Jianguo Xu*, and Guodong Liu. Selection of specific DNA aptamers for hetero-sandwich based colorimetric determination of Campylobacter jejuni in food. Journal of Agricultural and Food Chemistry. 2020, 68, 31, 8455–8461

12. Wei Chen*, Lijun Yang, Chao Yan, Bangben Yao, Jian-feng Lu, Jianguo Xu*, and Guodong Liu*. Surface-confined building of Au@Pt-centered and multi-G-quadruplex/hemin wires-surrounded electroactive supernanostructures for ultrasensitive monitoring of morphine. ACS Sensors. 2020, 5, 8, 2644–2651

13. Jie Wang, Shuhui Li, Jianguo Xu*, Yusheng Lu, Min Lin, Chaihung Wang, Chen Zhang, Guoxing Lin, Lee Jia*. Functionalized dumbbell probe-based cascading exponential amplification DNA machine enables amplified probing of microRNAs. Chemical Communications, 2020, 56, 1681-1684

14. Jianguo Xu#, Chao Yan#, Xinxin Wang, Bangben Yao, Jianfeng Lu, Guodong Liu*, Wei Chen*. Ingenious design of DNA concatamers and G-quadruplex wires assisted assembly of multi-branched DNA nanoarchitectures for ultrasensitive biosensing of miRNA. Analytical Chemistry, 2019, 91: 9747-9753

15. Wei Chen*, Fen Cai, Qian Wu, Yuhan Wu, Bangben Yao, Jianguo Xu*. Prediction, evaluation, confirmation, and elimination of matrix effects for lateral flow test strip based rapid and on-site detection of aflatoxin B1 in tea soup. Food chemistry, 2020, 328:127081.

16. Jianguo Xu, Zai-Sheng Wu*, Zhenmeng Wang, Jingqing Le, Tingting Zheng, Lee Jia*. Autonomous assembly of ordered metastable DNA nanoarchitecture and in situ visualizing of intracellular microRNAs, Biomaterials, 2017, 120: 57-65

17. Jianguo Xu, Zai-Sheng Wu*, Zhenmeng Wang, Hongling Li, Jingqing Le, and Lee Jia*, Two-wheel drive-based DNA nanomachine and its sensing potential for highly sensitive analysis of cancer-related gene, Biomaterials, 2016, 100: 110-117

18. Jianguo Xu, Hongling Li, Zai-Sheng Wu*, Jun Qian, Chang Xue, Lee Jia*. Double-stem hairpin probe and ultrasensitive colorimetric detection of cancer-related nucleic acids, Theranostics, 2016, 6: 318-327

19. Jianguo Xu, Zai-Sheng Wu*, Weiyu Shen, Jingqing Le, Tingting Zheng, Hongling Li, Lee Jia*. Programmable nanoassembly consisting of two hairpin-DNAs for p53 gene determination, Biosensors and Bioelectronics, 2017, 94: 626-631

20. Jianguo Xu, Zai-Sheng Wu*, Hongling Li, Zhenmeng Wang, Jingqing Le, Tingting Zheng, Lee Jia*. Dual-cyclical nucleic acid strand-displacement polymerization based signal amplification system for highly sensitive determination of p53 Gene, Biosensors and Bioelectronics, 2016, 86: 1024-1030

21. Jianguo Xu#, Jun Qian#, Hongling Li, Zai-Sheng Wu*, Weiyu Shen, Lee Jia*, Intelligent DNA machine for the ultrasensitive colorimetric detection of nucleic acids, Biosensors and Bioelectronics, 2016, 75: 41-47

22. Jianguo Xu, Haiyan Dong, Weiyu Shen, Sudan He, Hongling Li, Yusheng Lu, Zai-Sheng Wu*, Lee Jia*. New molecular beacon for p53 gene point mutation and significant potential in serving as the polymerization primer, Biosensors and Bioelectronics, 2015, 66: 504-511

23. Jianguo Xu, Zai-Sheng Wu*, Weiyu Shen, Huo Xu, Hongling Li, Lee Jia*. Cascade DNA nanomachine and exponential amplification biosensing, Biosensors and Bioelectronics, 2015, 73: 19-25

24. Hongbo Li*, Mingbin Liu, Weihua Zhao, Jiamei Pu, Jianguo Xu*, Suqin Wang, Ruqin Yu*. Multi-channel collection of G-quadruplex transducers for amplified signaling of Pax-5 based on target-triggered split-to-intact remodeling of dual-G-rich duplex probe. Sensors & Actuators: B. Chemical, 2020, 311: 127913-127929

25. Xiaoming Ma, Shan He, Ying Zhang, Jianguo Xu*, Huifang Zhang, Zhen Wang, Jun Xue, Xun Li,* Wenbo Yu*. Xiaolin FanaSignal-off tuned signal-on (SF-T-SN) colorimetric immunoassay for amantadine using activity-metalmodulated peroxidase-mimicking nanozyme. Sensors & Actuators: B. Chemical, 2020, 311, 127933-127938

26. Xinxin Wang, Jianguo Xu*, Panzhu Qin, Chao Yan, Guodong Liu, Wei Chen*. Automated nanoassembly of poly-thymine embedded activatable molecular beacon for one-step quantification of the terminal deoxynucleotidyl transferase activity. Analytica Chimica Acta. 2021, 1141, 127-135

27. Jianguo Xu, Zai-Sheng Wu*, Yanru Chen, Tingting Zheng, Jingqing Le, Lee Jia*. Collapse of chain anadiplosis-structured DNA nanowires for highly sensitive colorimetric assay of nucleic acids, Analyst, 2017, 142: 613-620

28. Jianguo Xu#, Tingting Zheng#, Jingqing Le, Lee Jia*, Long-stem shaped multifunctional molecular beacon for highly sensitive nucleic acids determination via intramolecular and intermolecular interactions based strand displacement amplification, Analyst, 2017, 142: 4438–4445

29. Zhengrong Zhang, Shisheng Chen, Jianluan Ren, Fang Han, Xiaofeng Yu, Fang Tang, Feng Xue*, Wei Chen, Jielin Yang, Yuan Jiang, Hongmei Jiang, Bo Lv, Jianguo Xu*, Jianjun Dai. Facile construction of a Molecularly Imprinted Polymer based Electrochemical Sensor for the Detection of milk amyloid A. Microchimica Acta. 2020, 187, 642.

30. Li Yao, Yulin Li, Kewen Cheng, Daodong Pan, Jianguo Xu*, Wei Chen*,*Determination of 17β-estradiol by surface-enhanced Raman spectroscopy merged with hybridization chain reaction amplification on Au@Ag core-shell nanoparticles. Microchimica Acta, 2019, 186(2): 52.

31. Xiaoming Ma, Zhen Wang, Shan He, Jingyi Zhao, Xiaoqi Lai*, Jianguo Xu*. L-cysteine modified gold nanoparticles for tube-based fluorometric determination of mercury(II) ions. Microchimica Acta, 2019, 186(9): 632.

32. Jianguo Xu, Tingting Zheng, Jingqing Le, Lee Jia*, Stepwise nanoassembly of a single hairpin probe and its biosensing, Talanta, 2018, 187, 272-278

33. Panzhu Qin, Dongqing Qiao, Yan Gao, Li Yao, Jianfeng Lu, Jianguo Xu*, Wei Chen*. Self-signal-on fluorescent colorimetric protocol for rapid authentication of horsemeat adulterated beef samples with functional designed probes. International Journal of Food Science & Technology, 2019, 54(5): 1752-1759.

34. Panzhu Qin, Wei Qu, Jianguo Xu*, Dongqing Qiao, Li Yao, Feng Xue, Wei Chen*. A sensitive multiplex PCR protocol for simultaneous detection of chicken, duck, and pork in beef samples. Journal of food science and technology, 2019, 56(3): 1266-1274.

35. Chao Yan, Lijun Yang, Li Yao, Jianguo Xu, Bangben Yao, Guodong Liu*, Lin Cheng, and Wei Chen*. Ingenious Electrochemiluminescence Bio-aptasensor based on Synergistic Effects and Enzyme-Drive Programmable 3D DNA Nanoflowers for Ultrasensitive Detection of Aflatoxin B1. Analytical Chemistry, 2020, 92, 20, 14122-14129. (IF= 6.785, 一区)

36. Wei Chen, Xinni Li, Qian Wu, Li Yao, Jianguo Xu*. Rapid and easy determination of morphine in chafing dish condiments with colloidal gold labeling based lateral flow strips. Food Science and Human Wellness, 2019, 8(1): 40-45.

37. Jianguo Xu*, Xinxin Wang, Chao Yan, Wei Chen*. A Polyamidoamine Dendrimer-Based Electrochemical Immunosensor for Label-Free Determination of Epithelial Cell Adhesion Molecule-Expressing Cancer Cells. Sensors, 2019, 19(8): 1879.

38. Li Yao, Yinji Chen, Jun Teng, Wanli Zheng, Jingjing Wu, Samuel B. Adeloju, Daodong Pan, Wei Chen*. Integrated platform with magnetic purification and rolling circular amplification for sensitive fluorescent detection of ochratoxin A. Biosensors and Bioelectronics, 2015,  74: 534-538. (SCI 收录, IF=9.518)

39. Qian Wu, Qing Song, Xinxin Wang, Li Yao, Jianguo Xu, Jianfeng Lu, Guodong Liu, Wei Chen*. Simultaneous detection of multiple β-adrenergic agonists with 2-directional lateral flow strip platform. Analytical Sciences, 2020, 36: 653-658.

40.Panzhu Qin, Jianguo Xu, Li Yao, Qian Wu, Chao Yan, Jianfeng Lu, Bangben Yao, Guodong Liu, Wei Chen*.Simultaneous and accurate visual identification of chicken, duck and pork components with the molecular amplification integrated lateral flow strip. Food chemistry, 2020, 339:127891.

41. Li Yao, Jun Teng, Hao Qu, Mengya Zhu, Lei Zheng, Feng Xue,Wei Chen*. Paper matrix-based array for rapid and sensitive optical detection of mercury ions using silver enhancement. Microchimica Acta, 2016, 184(2), 1-8. (SCI 收录, IF=5.479)

42. Li Yao, Yingwang Ye, Jun Teng, Feng Xue, Daodong Pan, Baoguang Li, Wei Chen*. In Vitro Isothermal Nucleic Acid Amplification Assisted SurfaceEnhanced Raman Spectroscopic for Ultrasensitive Detection of Vibrio parahaemolyticus. Analytical Chemistry, 2017, 89, 9775-9780. (SCI 收录, IF=6.35,)

43. Li Yao, Yulin Li, Kewen Cheng, Daodong Pan, Jianguo Xu*, Wei Chen*. Determination of 17β-Estradiol by surface-enhanced Raman spectroscopy merged with hybridization chain reaction amplification on Au@Ag core-shell nanoparticles Microchimica Acta, 2019, 186, 52-60. (SCI 收录, IF=5.479)

44. Li Yao, Jianguo Xu, Bangben Yao, Lei Zheng, Guodong Liu*, Wei Chen*. SERS-decoding: Simultaneous detection of multiple genetically modified organism (GMO) components on the same test line of lateral flow strip. (In the process of submission)

45. Yinji Chen, Li Yao, Yi Deng, Daodong Pan, Edward Ogabiela, Jinxuan Cao, Samuel B. Adeloju, Wei Chen*. Rapid and ultrasensitive colorimetric detection of mercury (II) by chemically initiated aggregation of gold nanoparticles. Microchimica Acta, 2015, 182(13-14): 2147-2154. (SCI 收录, IF=5.479)

46. Jun Teng, Yingwang Ye, Li Yao, Chao Yan, Kewen Cheng, Feng Xue, Daodong Pan, Baoguang Li, Wei Chen*. Rolling circle amplification based amperometric aptamer/immuno hybrid biosensor for ultrasensitive detection of Vibrio parahaemolyticus. Microchimica Acta, 2017, 184: 3477-23485. (SCI 收录, IF=5.479)

47. Chao Yan, Jing Zhang, Li Yao, Feng Xue, Jianfeng Lu*, Baoguang Li, Wei Chen*. Aptamer-mediated colorimetric method for rapid and sensitive detection of chloramphenicol in food. Food Chemistry, 2018, 260, 208-212. (IF= 6.306, 一区)

48. Chao Yan, Jun Teng, Fengyin Liu, Bangben Yao, Zhenlin Xu*, Li Yao, Wei Chen*. Signal amplifed enzyme-linked immunosorbent assay with gold nanoparticles for sensitive detection of trace furaltadone metabolite. Microchemical Journal, 2020, 159, 105414. (IF= 3.594, 二区)

49. Xinxin Wang, Jianguo Xu*, Panzhu Qin, Chao Yan, Guodong Liu, Wei Chen*. Self-assembly of a polythymine embedded activatable molecular beacon for one-step quantification of terminal deoxynucleotidyl transferase activity. Analytica Chimica Acta, 2021,

50. Yanan Zhao, Dexin Zeng, Chao Yan, Wei Chen, Jianluan Ren, Yuan Jiang, Luyan Jiang, Feng Xue*, Dejun Ji, Fang Tang, Mingqiang Zhou* and Jianjun Dai. Rapid and accurate detection of Escherichia coliO157:H7 in beef using microfluidic wax-printed paper-based ELISA. Analyst, 2020, 145, 3106-3115. (IF= 3.978, 二区)

51. Panzhu Qin, Dongqing Qiao, Jianguo Xu, Qing Song, Li Yao, Jianfeng Lu*, Wei  Chen*. Rapid visual sensing and quantitative identification of duck meat in  adulterated beef with a lateral flow strip platform. Food Chemistry, 2019, 294,  224-230. (IF 6.306,一区)

52. Panzhu Qin, Li Yao, Jianguo Xu*, Guodong Liu*, Wei Chen*. Smart  engineering of a dual-DNA machine with high signal-to-noise ratio for one-pot  robust and sensitive miRNA signaling. Chemical Communications, 2019, 55,14367-14370.(IF 5.996,二区,自然指数期刊)

53. Panzhu Qin, Dongqing Qiao, Yan Gao, Li Yao, Jianfeng Lu, Jianguo Xu*, Wei  Chen*. Self-signal-on fluorescent colorimetric protocol for rapid authentication  of horsemeat adulterated beef samples with functional designed probes.  International Journal of Food Science and Technology, 2019, 54, 1752–1759.  (IF 2.773,三区)

54. Panzhu Qin, Jianguo Xu, Li Yao, Bangben Yao, Lin Cheng, Jianfeng Lu*, Wei  Chen*. Self-sustained multi-leg elongation based multi-leg elongation with a  snowballing effect for fluorescence polarization-sensitized determination of  terminal deoxynucleotidyl transferase activity. (In peer review: Analytical  Chemistry)

55. Panzhu Qin, Yulin Li, Lin Cheng, Bangben Yao, Jianguo Xu*, Wei Chen*.  Rational incorporating of loop-mediated isothermal amplification with  fluorescence anisotropy for rapid, sensitive and on-site identification of pork  adulteration. (In peer review: Meat Science)

56. X.X Wang, X.L Zhang, et al. Periodically programmed building and  collapse of DNA networks enables an ultrahigh signal amplification effect for  ultrasensitive nucleic acids analysis. Analytica Chimica Acta. J.G Xu,

57. Wanli Zheng, Li Yao, Jun Teng, Chao Yan, Panzhu Qin, Guodong Liu*, Wei  Chen*. Lateral flow test for visual detection of multiple MicroRNAs. Sensors  and Actuators B: Chemical, 2018, 264, 320-326. (IF 7.1,一区)

二、 专著:

1. Jianguo Xu, Li Yao, Lin Cheng, Chao Yan, and Wei Chen*. “Development of Aptamer-Based Electrochemical Methods.” Aptamers for Analytical Applications: Affinity Acquisition and Method Design, Willey publishing, 2018: 247-271.

2.《食品安全学》,郑州大学出版社,编委,2019年12月

三、授权专利:

1. 陈伟,胥传来,郑磊,刘永胜,余晓峰,陈寒青,梅占龙,吴晶晶,一种信号增强型免疫层析金标试纸条的制备方法,ZL 201110331811.6;

2. 陈伟,吴晶晶,薛峰,梅占龙,张睿,陈寒青,蒋原,利用电化学核酸适配体传感器一步快速检测赭曲霉毒素 A 的方法,ZL 201210194317.4;

3. 陈伟, 黄琳, 赵第萍, 姚丽, 强抗基质干扰型双酚 A 上转换荧光层析试纸条的制备方法,ZL 201410109117.3

4. 汞离子胶体金比色检测法及汞离子检测试剂盒,专利号:201410146113.2,发明人:陈伟,邓怡,姚丽,朱梦雅。

5. 碳纳米管标记的试纸、其制备方法及快速检测Hg2+的方法, 专利号:ZL 2016 1 0220203.0  发明人:陈伟,姚丽,滕军,钟有好,邓怡,陈玉英。

6. 薛峰,滕军,蒋原,陈伟,李东明,曾德新,夏晓莉,邵景东,一种检测致病菌的试剂盒及其应用

7. 薛峰,滕军,蒋原,陈伟,蒋鲁岩,袁芳,曾德新,夏晓莉,邵景东,检测致病菌的电化学传感器、制备方法及其应用