食品安全快速检测及生物传感课题组负责人
开展食品安全快速、 超灵敏检测新方法建立的基础和应用研究,克服传统食品安全检测方法“检不快”、“检不准”以及“检不多”等实际应用难点,在 Angew. Chem. Int. Ed, Nano Letters, Analytical Chemistry, Biosensors&Bioelectronics, Food Chemistry 等国际期刊发表 SCI 论文 81 篇,影响因子>5 的 47 篇,Web of Science 统计,被 Nature Nanotechn.Nature Materials、Chem. Soc. Rev.等引用4116次,其中单篇引用超过100次9篇,超过50次24篇,H-index 36。获得授权专利 10 项,作为主编及编委,分别完成了《食品免疫化学与分析》撰写,以及英文书籍《Aptamers for Analytical Applications-Affinity Optimization and MethodDesign》(Published by Wiley)中《Development of aptamer-based electrochemical methods》章节的编写工作,研究成果获得安徽省自然科学一等奖,国家质检总局科技兴检奖一等奖 2 次,中国检验检疫协会科技奖一等奖,湖南省科技进步奖一等奖,安徽省科技进步奖三等奖等。
代表性文章:
1. Lin Huang, Wei Chen*, et al. Rolling Chain Amplification Based Signal-Enhanced Electrochemical Aptasensor for Ultrasensitive Detection of Ochratoxin A, Analytical Chemistry, 2013, 85, 10842-10849;
2. Wei Chen, Dinghua Xu, Liqiang Liu, et al. Ultrasensitive Detection of Trace Protein by Western Blot Based on POL Y -Quantum Dot Probes, Analytical Chemistry, 2009, 81, 9194-9198;
3. Li Y ao, Yingwang Y e, Wei Chen*, et al. In Vitro Isothermal Nucleic Acid Amplification Assisted Surface-Enhanced Raman Spectroscopic for Ultrasensitive Detection of Vibrio parahaemolyticus, Analytical Chemistry, 2017, 89, 9775-9780;
4. DongqingQiao, Jianguo Xu, Wei Chen*, et al. Highly Simple and Sensitive Molecular Amplification-Integrated Fluorescence Anisotropy for Rapid and On-Site Identification of Adulterated Beef, Analytical Chemistry, 2018, 90, 7171-7175;
5. Wei Chen, Chao Yan, Lin Cheng, et al. An ultrasensitive signal-on electrochemical aptasensor for ochratoxin A determination based on DNA controlled layer-by-layer assembly of dual gold nanoparticle conjugates, Biosensors & Bioelectronics, 2018, 117, 845-851;
6. Zhanlong Mei, Wei Qu, Wei Chen*, et al. One-step signal amplified lateral flow strip biosensor for ultrasensitive and on-site detection of bisphenol A (BPA) in aqueous samples, Biosensors & Bioelectronics, 2013, 49, 457-461;
7. Mengya Zhu Ying Wang, Wei Chen*, et al.Ultrasensitive detection of mercury with a novel one-step signal amplified lateral flow strip based on gold nanoparticle-labeled ssDNA recognition and enhancement probes, Biosensors & Bioelectronics, 2014, 61, 14-20;
8. Li Y ao, Jun Teng, Wei Chen*, et al. MWCNTs based high sensitive lateral flow strip biosensor for rapid determination of aqueous mercury ions, Biosensors & Bioelectronics, 2016, 85, 331-336.
9. Yi Deng, Xin Wang, Wei Chen*, et al. Ultrasensitive and rapid screening of mercury(II) ions by dual labeling colorimetric method in aqueous samples and applications in mercury-poisoned animal tissues, Analytica Chimica Acta, 2015, 868, 45-52;
10. Jingjing Wu, Huaqin Chu, Wei Chen*, et al. Ultrasensitive one-step rapid detection of ochratoxin A by the folding-based electrochemical aptasensor, Analytica Chimica Acta, 2012, 753, 27-31;
授权专利:
1. 陈伟,胥传来,郑磊,刘永胜,余晓峰,陈寒青,梅占龙,吴晶晶,一种信号增强型免疫层析金标试纸条的制备方法,ZL 201110331811.6;
2. 陈伟,吴晶晶,薛峰,梅占龙,张睿,陈寒青,蒋原,利用电化学核酸适配体传感器一步快速检测赭曲霉毒素 A 的方法,ZL 201210194317.4;
3. 陈伟, 黄琳, 赵第萍, 姚丽, 强抗基质干扰型双酚 A 上转换荧光层析试纸条的制备方法,ZL 201410109117.3