Dr. Rajiv Gandhi Gopalsamy

EDUCATION

Doctor of Philosophy (Biochemistry) 

From University of Madras, Chennai India January 2009- September 2015.

Master of Philosophy (Biochemistry)

From Bharathidasan University, Trichy, India 2007-2008.

Master of Science (Biochemistry)

From Bharathidasan University, Trichy, India 2005-2007.

Bachelor of Science (Biochemistry)

From St. Joseph’s College, Cuddalore Affiliated to University of Madras, India 2002-2005.

RESEARCH INTEREST

• Pharmacology

• Phytomedicine

• Molecular Biology

PUBLICATIONS

2020

• G R Gandhi, D Karthik , A B S Vasconcelos, G C S Leão, M L D Almeida, G Sridharan, G Jothi, T Mohana, N Narain , R Q Gurgel. Flavonoids as cytokine immunomodulators to reduce airway inflammation via inhibition of the NF-κB signalling pathway: A systematic overview. (June, 2020) In: eLS Book. Chapter, John Wiley & Sons, Ltd: Chichester. DOI: 10.1002/9780470015902.a0028888

• S R Gandhi, J S S Quintans, G R Gandhi, A A S Araújo,  L J Q Júnior. The use   of cyclodextrins inclusion complexes to improve anti-cancer drug profiles - A systematic review. Expert Opinion on Drug Delivery. (May, 2020) Article  in Press (Impact factor: 5.400). https://doi.org/10.1080/17425247.2020.1776261 (ISSN: 1742-5247)

• G R Gandhi, G C S Leão, V K S Calisto, A B S Vasconcelos, M L D Almeida, J  S S Quintans, E Barreto, N Narain, L J Q Júnior, R Q Gurgel. Modulation of interleukin expression by medicinal plants and their secondary metabolites: a systematic review on anti-asthmatic and immunopharmacological mechanisms. Phytomedicine. (April, 2020) 70: 153229 (Impact factor: 4.268) (ISSN: 0944- 7113)

2019

• G R Gandhi, A B S Vasconcelos, G H Haran, V K D S Calisto, G Jothi, J S S Quintans, L E Cuevas, N Narain, L J Q Júnior, R Cipolotti, R Q Gurgel. Essential oils and its bioactive compounds modulating cytokines: A systematic review on anti-asthmatic and immunomodulatory properties. Phytomedicine.  (January,  2019) Article ID, 152854. doi: 10.1016/j.phymed.2019.152854 (Impact factor: 4.268) (ISSN: 0944-7113)

2018

• G R Gandhi, M T S L Neta, R G Sathiyabama, J S Siqueira Quintans, A M O E Silva,  A A S Araújo,  N Narain,  L J   Quintans-Júnior,   R Q Gurgel. Flavonoids as Th1/Th2 cytokines immunomodulators: A systematic review of studies on animal models, Phytomedicine (Stuttgart). (May, 2018) 15: 74-84.  (Impact factor: 4.268) (ISSN: 0944-7113)

• R G Sathiyabama,  G R Gandhi,  M Denadai, G  Sridharan, G Jothi, P Sasikumar,  J S Siqueira Quintans, N Narain,  L E Cuevas,  H D M Coutinho,  A G B Ramos,  L J Quintans-Júnior, R Q Gurgel. Evidence of insulin-dependent signaling mechanisms produced by Citrus sinensis (L.) Osbeck fruit peel in an insulin resistant diabetic animal model. Food and Chemical Toxicology (July, 2018) 116: 86-99. (Impact factor: 4.679) (ISSN: 0278 - 6915)

2017

• G R Gandhi, V S Santos, M Denadai, V K D S Calisto, J S S Quintans, A M D Silva, A A S Araújo, N Narain, L Cuevas, L J Q Júnior, R Q Gurgel. Cytokines in the management of rotavirus infection: A systematic review of in vivo studies. Cytokine. (May, 2017) 96: 152-160. (Impact factor: 2.952) (ISSN: 1043-4666)

• P J Antony, G R Gandhi, A Stalin, K Balakrishna, E Toppo, K Sivasankaran, S Ignacimuthu, N A Al-dhabi. Myoinositol ameliorates high-fat diet and streptozotocin-induced diabetes in rats through promoting insulin receptor signaling. Biomedicine & pharmacotherapy. (February, 2017) 88: 1098-1113. (Impact factor: 4.545) (ISSN: 0753-3322)

2016

• G R Gandhi, P G Barreto, B S Lima, J S S Quintans, A A S Araújo, N Narain, L   J Q Júnior, R Q Gurgel. Medicinal plants and natural molecules with in vitro and  in vivo activity against rotavirus: A systematic review. Phytomedicine (Stuttgart). (November, 2016) 23: 1830-1842. (Impact factor: 4.268) (ISSN: 0944-7113)

• J C Silva, J R G S. Almeida, J S S Quintans, G R Gandhi, S Shanmugam, M R Serafini, M R C Oliveira, B A F Silva, A O B P B Martins, F F Castro, I R A Menezes, H D M Coutinho, R C M Oliveira, P Thangaraj, A A S Araújo, L J Quintans-Júnior. Enhancement of orofacial antinociceptive effect of carvacrol, a monoterpene present in oregano and thyme oils, by β-cyclodextrin inclusion complex in mice. Biomedicine and Pharmacotheraphy (September, 2016) 84: 454-461. (Impact factor: 4.545) (ISSN: 0753-3322)

• A Stalin, S S Irudayaraj, G R Gandhi, K Balakrishna, S Ignacimuthu, N A Al- Dhabi. Hypoglycemic activity of 6-bromoembelin and vilangin  in  high-fat  diet fed streptozotocin-induced type 2 diabetic rats and molecular  docking  studies. Life Sciences (May, 2016) 153: 100-117. (Impact Factor: 3.647) (ISSN: 0024 - 3205)

2014

• G R Gandhi, G Jothi, P J Antony, K Balakrishna, M G Paulraj, S Ignacimuthu, A Stalin, N A Al-Dhabi. Gallic acid attenuates high-fat diet fed-streptozotocin- induced insulin resistance via partial agonism of PPARγ in experimental type 2 diabetic rats and enhance glucose uptake through translocation and activation of GLUT4 in PI3K/p-Akt signaling pathway. European Journal of Pharmacology (December, 2014), 745: 201-216. (Impact Factor: 3.263) (ISSN: 0014 - 2999)

• G R Gandhi, P Vanlalhruaia, A Stalin, S S Irudayaraj, S Ignacimuthu, M  G  Paulraj. Polyphenols-rich Cyamopsis tetragonoloba (L.) Taub. beans show hypoglycemic   and   β-cells   protective   effects   in   type   2   diabetic    rats. Food and Chemical Toxicology (April, 2014), 66: 358-365. (Impact Factor: 4.679) (ISSN: 0278 - 6915)

2013

• G R Gandhi, A Stalin, K Balakrishna, S Ignacimuthu, M G Paulraj, R Vishal. Insulin sensitization via partial agonism of PPARγ and glucose uptake through translocation and activation of GLUT4 in PI3K/p-Akt signaling pathway by embelin in type 2 diabetic rats. Biochimica et Biophysica Acta - General Subjects (January, 2013), 1830: 2243-2255. (Impact Factor: 3.422) (ISSN: 0304 - 4165)

2012

• G R Gandhi, S Ignacimuthu, M G Paulraj. Hypoglycemic and  β-cells  regenerative effects of Aegle marmelos (L.) Corr. bark extract in streptozotocin- induced diabetic rats, Food and Chemical Toxicology (May, 2012), 50:1667-  1674. (Impact Factor: 4.679) (ISSN: 0278 - 6915)

• R Vidhya, G R Gandhi, G Jothi, J Radhika, P Brindha. Evaluation of antidiabetic potential of Achyranthes aspera Linn. on alloxan induced diabetic animals. International Journal of Pharmacy and Pharmaceutical Sciences (2012), 4, 577- 580. (ISSN: 0975 - 1491)

• G R Gandhi, P Sasikumar. Antidiabetic effect of Merremia emarginata Burm. F. in streptozotocin induced diabetic rats. Asian Pacific Journal of Tropical Biomedicine (April, 2012), 281-286. (Impact Factor: 1.903) (ISSN: 2221-1691)

2011

• G R Gandhi, S Ignacimuthu, M G Paulraj. Solanum torvum Swartz. fruit containing phenolic compounds shows antidiabetic and antioxidant effects in streptozotocin-induced diabetic rats, Food and Chemical Toxicology (November, 2011), 49:2725 - 2733. (Impact Factor: 4.679) (ISSN: 0278 - 6915)

• G R Gandhi, S Ignacimuthu, M G Paulraj, P Sasikumar. Antihyperglycemic activity and antidiabetic effect of methyl caffeate isolated from Solanum torvum Swartz. fruit in streptozotocin-induced diabetic rats. European Journal of Pharmacology (November, 2011), 670:623- 631. (Impact Factor: 3.263) (ISSN: 0014 - 2999)