1. Natural prodocut-based drug discovery

Drugs originated from natural product bear greater chemical diversity and larger regions of chemical space than fully synthetic drugs. By combining modular chemical synthesis, rational drug design and modern structural biology technique, natural product-based drug discovery plays a great role in future medicinal chemstry.

2. Development of skeleton-based methodology

Development of novel methods in building specific skeleton provides libraries in drug discovery.

Modular chemical synthesis, modification and target confirmation of bioactive natural products.