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Chen Lab at Fuzhou University
Native peptide cyclization and modification
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Fa-Jie Chen
Associate Professor
Native peptide cyclization and modification
Fa-Jie Chen received his B.S. degree in 2011 from Fuzhou University (China.). He completed his Ph.D. in 2016 in chemistry with Prof. Bing-Feng Shi and Prof. Jun Wu from Zhejiang University (China). His research focused on transition metal-catalyzed carbon-hydrogen bond functionalization using a removable directing group. After postdoctoral training at Fujian Institute of Research on the Structure of Matter (with Prof. Weiping Su) and University of Illinois at Chicago (with Prof. Daesung Lee), he joined the group of Prof. Jianmin Gao in 2020 as a postdoctoral fellow and works on cysteine-specific peptide and protein modifications. He is currently an associate professor at the College of Chemistry, Fuzhou University. His research interest is the development of new synthetic methods aimed at the cyclization or chemo- and site-specific modification of native peptides, and the development of peptide-based drugs for peptide therapeutics.
Research
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Native peptide cyclization/ chemo- and site-specific modification
News
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Our paper is featured on the Cover of Nat. Rev. Chem. (May issue)!
We are awarded a new Fuzhou University Testing Fund to continue our study of peptide engineering!
We have published a News & Views in Nat. Rev. Chem. highlighting recent advance in non-symmetric stapling of native peptides
Our work on the synthesis of glycoconjugates using chlorooxime-thiol conjugation is published in JOC! Congrats, Wang!
Our review has been published in Nature Review Chemistry! Cheer!
Our review on multicyclic phage display libraries published in ChemBioChem!
Our collaborative work on Cu-catalyzed arylation of S-tosyl peptides with arylboronic acids is published in Org. Chem. Front.! Congrats!
Two undergraduate students join our lab. Welcome Zihan and Yihui!
Welcome on board Yichi, Xin, and Wenkang!
Welcome on board Jingrong and Wang!
Events
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Literature Workshop
Reactions of the Week
Celebrating Wang's JOC paper!
Group party (03/06/2024)
Useful Links
Jianmin Gao Lab@BC