21. Wanzhen Lin,† Xin Ding,† Jun-Wei Han, Li-Shuang Yu,* and Fa-Jie Chen* "Polyfluorinated Reagents for Peptide Stapling"
Org. Chem. Front., 2025, Accepted. DOI: 10.1039/D5QO00112A (†Those authors contributed equally)
- Selected as "2025 Organic Chemistry Frontiers HOT articles"
20. Zihan Lin, Wanzhen Lin*, Fa-Jie Chen* "Electrochemical Modifications of Native Peptides"
19. Fa-Jie Chen* "Another Side of Side Chains"
Nat. Rev. Chem. 8, 406-407 (2024) (News & Views)
- View-only version: https://rdcu.be/dGxyT
18. Wang Gu, Jingrong Huang, Yichi Lu, Wanzhen Lin*, Wei Xu*, Fa-Jie Chen* "Synthesis of Glycoconjugates through Chlorooxime-Thiol Conjugation"
J. Org. Chem., 2024, 89, 9, 6364–6370
17. Fa-Jie Chen*;# Wanzhen Lin;# Fen-Er Chen* "Non-symmetric Stapling of Native Peptides"
Nat. Rev. Chem. 8, 304-318 (2024) (#Those authors contributed equally)
- View-only version: https://rdcu.be/dDF8q
- Selected as Cover Image
16. Fa-Jie Chen*,# Nicole Pinnette,# Jianmin Gao*. "Strategies for the Construction of Multicyclic Phage Display Libraries"
ChemBioChem, 2024, e202400072. (VIP paper, Invited Review) (#Those authors contributed equally)
15. Junjie Ying, Jingrong Huang, Chenguang Liu, Fa-Jie Chen,* Chunfa Xu,* Fen-Er Chen* "Cu-Catalyzed Arylation of S-Tosyl Peptides with Arylboronic Acids"
Org. Chem. Front., 2024, 11, 53-59.
- Highlighted by Frontiers Journals
14. Fa-Jie Chen,# Nicole Pinnette,# Fan Yang, Jianmin Gao.* "A Cysteine-Directed Proximity-Driven Crosslinking Method for Native Peptide Bicyclization"
Angew. Chem. Int. Ed. 2023, e202306813. (#Those authors contributed equally)
- Highlighted by X-mol.
Before FZU
13. Chen, Fa-Jie; Gao, Jianmin.* "Fast Cysteine Bioconjugation Chemistry"
Chem. Eur. J. 2022, e202201843. (Invited Review)
12. Zheng, Mengmeng; Chen, Fa-Jie, Li, Kaicheng; Reja, Rahi M.; Haeffner, Fredrik; Gao, Jianmin* "Lysine-Targeted Reversible Covalent Ligand Discovery for Proteins via Phage Display"
J. Am. Chem. Soc. 2022, 144, 15885-15893.
- Highlighted by X-mol.
11. Chen, Fa-Jie;# Zheng, Mengmeng,# Nobile, Vincent, Gao, Jianmin.* "Fast and Cysteine-Specific Modification of Peptides, Proteins and Bacteriophage Using Chlorooximes"
Chem. Eur. J. 2022, e202200058. (Hot paper) (#Those authors contributed equally)
- Highlighted by WileyChem
10. Chen, Fa-Jie; Mamidipalli, Phani; Sabbasani, Venkatareddy; Liu, Huaqing; Lee, Daesung* Xia, Yuanzhi*. "Three-component Coupling Reaction for the Synthesis of Fully Substituted Triazoles: Reactivity Control of Cu-Acetylide toward Alkyl Azides and Diazo Compounds"
Org. Chem. Front., 2021, 8, 6095.
9. Chen, Fa-Jie; Hua, Zhenguo; Chen, Jianhui; Chen, Jiajia; Lee, Daesung* and Xia, Yuanzhi*. "One-Pot Synthesis of (Z)-β-Halovinyl Ketones via the Cascade of Sonogashira Coupling and Hydrohalogenation"
8. Chen, Fa-Jie; Lin, Yongjia; Xu, Man; Xia, Yuanzhi*; Wink, Donald J.; Lee, Daesung*. "C–H Insertion by Alkylidene Carbenes to Form 1,2,3-Triazines and Anionic [3 + 2] Dipolar Cycloadditions To Form Tetrazoles: Crucial Roles of Stereoelectronic and Steric Effects"
Org. Lett. 2020, 22, 2, 718-723.
7. Hu, Rong; Chen, Fa-Jie; Zhang, Xiaofeng; Zhang, Min; Su, Weiping.* "Copper-catalyzed Dehydrogenative γ-C(sp3)-H Amination of Saturated Ketones for Synthesis of Polysubstituted Anilines"
6. Zhao, Sheng; Chen, Fa-Jie; Liu, Bin; Shi, Bing-Feng.* "Copper-Catalyzed Direct Acyloxylation of C(sp2)-H Bonds with Benzoic Acids"
SCIENCE CHINA Chemistry, 2015, 58, 1302-1309.
5. Zhao, Sheng; Liu, Yue-Jin; Yan, Sheng-Yi; Chen, Fa-Jie; Zhang, Zhuo-Zhuo; Shi, Bing-Feng.* "Copper-/Silver-Mediated Arylation of C(sp2)–H Bonds with 2-Thiophenecarboxylic Acids."
Org. Lett. 2015, 17, 3338-3341.
4. Chen, Fa-Jie; Liao, Gang; Li, Xin; Wu, Jun*; Shi, Bing-Feng* "Copper-Mediated C–S/N–S Bond Formation via C–H Activation: Access to Benzoisothiazolones Using Elemental Sulfur"
Org. Lett. 2014, 6, 5644-5647.
3. Li, Xin; Liu, Yan-Hua; Gu, Wen-Jia; Li, Bo; Chen, Fa-Jie; Shi, Bing-Feng.* "Copper-Mediated Hydroxylation of Arenes and Heteroarenes Directed by a Removable Bidentate Auxiliary"
Org. Lett. 2014, 16, 3904-3907.
2. Zhang, Qi; Chen, Kai; Rao, Wei-Hao.; Zhang, Yuejun; Chen, Fa-Jie, Shi, Bing-Feng.* "Stereoselective Synthesis of Chiral α-Amino-β-Lactams via Pd(II)-Catalyzed Sequential Monoarylation/Amidation of C(sp3)–H Bonds"
Angew. Chem. Int. Ed. 2013, 52, 13588-13592.
- Highly Cited Paper
1. Chen, Fa-Jie; Zhao, Sheng; Hu, Fang; Chen, Kai; Zhang, Qi; Zhang, Shuo-Qing; Shi, Bing-Feng.* "Pd(II)-Catalyzed Alkoxylation of Unactivated C(sp3)–H and C(sp2)–H Bonds Using a Removable Directing Group: Efficient Synthesis of Alkyl Ethers"
Chem. Sci. 2013, 4, 4187-4192.
- Top 25 most-read Chemical Science articles in 2013
- Highly Cited Paper