个人简介

教育经历： 2000年大连理工大学本科毕业 2003年大连理工大学硕士毕业 2009年南开大学博士毕业 主要工作经历： 2003年-至今天津科技大学食品工程与生物技术学院 主要科研项目： 1.十三五国家重点研发计划任务”原薯鲜切制品关键技术研究及产品开发“ 2.十三五国家重点研发计划任务”传统酿造调味食品风味调控与优良菌种选育“ 3.十三五国家重点研发计划任务“中国传统酱油特色菌种安全评价及标准制定” 4.十二五国家科技支撑计划课题“增强免疫功能因子的关键制备技术及应用” 5.国家863计划“酱油安全低碳生产关键技术” 6.国家863计划“米曲霉基因组改造” 7.国家自然科学基金项目“纳豆菌脂肽诱导乳腺癌细胞凋亡的作用机制及其构效关系研究” 8.国家粮食局行业专项“基于细胞和动物模型之上的杂粮健康功效评价研究” 9.天津市科技计划项目“高盐稀态酱油质量安全控制技术生产性试验” 10.天津市应用基础重点项目“灰树花多糖结构、链构象与免疫调节作用机理”

研究领域

1.食品营养 2.天然产物的结构分析、功能评价及作用机理 3.传统酿造食品发酵机理与代谢调控

1.食品科学 2.食品营养

近期论文

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1.LirongHan,MengMeng,MingzhuGuo,DaiChengandChunlingWang*.Im-munomodulatoryactivityandmechanismofawater-solublepolysaccharideobtainedfromhighlandbarleyonimmunosuppressionmicemodels.Food&Function,2019,10:304-314. 2.M.-Z.Guo,M.Meng,C.-C.Feng,X.WangandC.-L.Wang*.AnovelpolysaccharideobtainedfromCraterelluscornucopioidesenhancesimmunomodulatoryactivityinimmunosuppressivemicemodelsviaregulationoftheTLR4-NF-κBpathway.Food&Function,2019,10(8):4792-4801. 3.MengMeng,MingzhuGuo,ChengchengFeng,RuhuaWang,DaiChengandChunlingWang*.Water-solublepolysaccharidesfromGrifolaFrondosafruitingbodiesprotectagainstimmunosuppressionincyclophosphamideinducedmiceviaJAK2/STAT3/SOCSsignaltransductionpathways.Food&Function,2019,10:4998-5007. 4.M.-Z.Guo,M.Meng,S.-Q.Duan,C.-C.Feng,C.-L.Wang⁎.Structurecharacterization,physicochemicalpropertyandimmunomodulatoryactivityonRAW264.7cellsofanoveltriple-helixpolysaccharidefromCraterellusCornucopioides.InternationalJournalofBiologicalMacromolecules,2019,126:796-804. 5.LirongHan,JunYu,YuanyuanChen,DaiCheng,XuWang,ChunlingWang*ImmunomodulatoryActivityofDocosahexaenoicAcidonRAW264.7CellsActivationthroughGPR120-MediatedSignalingPathway.JournalofAgriculturalandFoodChemistry,2018,66:926-934. 6.ShuomingWei,DaiCheng,HaifenYu,XufengWang,ShuminSong,ChunlingWang*.Millet-enricheddietsattenuatehighsalt-inducedhypertensionandmyocardialdamageinmalerats.JournalofFunctionalFoods,2018,44:304-312. 7.ShuminSong,DaiCheng,ShuomingWei,XufengWang,YabingNiu,WentaoQi,ChunlingWang*.PreventiveeffectofgenisteinonAOM/DSS-inducedcolonicneoplasmbymodulatingthePI3K/AKT/FOX3signalingpathwayinmicefedahigh-fatdiet.JournalofFunctionalFoods,2018,46:237-242. 8.LirongHan,HuannaLei,ZiweiTian,XuWang,DaiChengandChunlingWang*. Theimmunomodulatoryactivityandmechanismofdocosahexaenoicacid(DHA)onimmunosuppressivemicemodels.Food&Function,2018,9:3254-3263. 9.MengMeng,DaiCheng,LirongHan,YuanyuanChen,ChunlingWang*.Isolation,purification,structuralanalysisandimmunostimulatoyactivityofwater-solublepolysaccharidesfromGrifolaFrondosafruitingbody.CarbohydratePolymers,2017,157:1134-1143. 10.LirongHan,ShuminSong,YabingNiu,MengMengandChunlingWang*.EicosapentaenoicAcid(EPA)InducedMacrophagesActivationthroughGPR120-MediatedRaf-ERK1/2-IKK-NF-κBp65SignalingPathways.Nutrients,2017,9(9):937. 11.DaiCheng,ZhaodongWan,XinyuZhang,JianLi,HeLiandChunlingWang*. DietaryChlorellavulgarisAmelioratesAlteredImmunomodulatoryFunctionsinCyclophosphamide-InducedImmunosuppressiveMice.Nutrients,2017,9(7):2016-2022. 12.XiaoleiMa,MengMeng,LirongHan,DaiCheng,XiaohongCaoandChunlingWang*.StructuralcharacterizationandimmunomodulatoyactivityofGrifolafrondosapolysaccharideviatoll-likereceptor4-mitogen-activatdproteinkinases-nuclearfactorκBpathways.Food&Function,2016,7:2763-2772. 13.LirongHan,YuanyuanZhang,MengMeng,DaiChengandChunlingWang*.EicosapentaenoicacidinducedSKOV-3cellapoptosisthroughERK1/2–mTOR–NF-κBpathways.Anti-CancerDrugs,2016,27(7):635-642. 14.ChengDai,ZhangXinyu,MengMeng,HanLirong,LiZheng,HouLihua,QiWentao,WangChunling*.Theprotectiveeffectofabuckwheat-enrichddietonrenalinjuryinhighsalt-inducedhypertensioninrats.Food&Function,2016,7(8):3548-3554. 15.DaiCheng,XinyuZhang,MengMeng,LirongHan,CaijiaoLi,LihuaHou,WentaoQi,ChunlingWang∗.InhibitoryeffectonHT-29coloncancercellsofawater-solublepolysaccharideobtainedfromhighlandbarley.InternationalJournalofBiologicalMacromolecules,2016,92:88-95. 16.YuanyuanZhang,ChuanLiu,BinDong,XiaoleiMa,LihuaHou,XiaohongCaoandChunlingWang*.Anti-inflammatoryActivityandMechanismofSurfactininLipopolysaccharide-ActivatedMacrophages.Inflammation,2015,38(2):756-764. 17.YuanyuanZhang,LirongHan,WentaoQi,DaiCheng,XiaoleiMa,LihuaHou,XiaohongCao,ChunlingWang*.Eicosapentaenoicacid(EPA)inducedapoptosisinHepG2cellsthroughROS-Ca2+-JNKmitochondrialpathways.BiochemicalandBiophysicalResearchCommunications,2015,456(4):926-932. 18.ChunlingWang∗,MengMeng,ShengbinLiu,LiruiWang,LihuaHou,XiaohongCao.AchemicallysulfatedpolysaccharidefromGrifolafrondosinducesHepG2cellapoptosisbynotch1-NF-κBpathway.CarbohydratePolymers,2013,95:282-287. 19.ChunlingWang*,ChuanLiu,Li-liNiu,Li-ruiWang,Li-huaHou,Xiao-hongCao.Surfactin-InducedApoptosisThroughROS–ERS–Ca2+-ERKPathwaysinHepG2Cells.CellBiochemistryandBiophysics,2013,67(3):1433-1439. 20.XiaoleiMa，FuchuanZhou，YuanyuanChen，YuanyuanZhang，LihuaHou，XiaohongCao，ChunlingWang*.ApolysaccharidefromGrifolafrondosarelievesinsulinresistanceofHepG2cellbyAkt-GSK-3pathway,GlycoconjJ,2014,31:355–363.

学术兼职

天津市食品安全专家咨询委员会专家委员、天津市调味品协会副会长、美国IFT会员，国家自然基金委网评专家，Food Chemistry, Carbohydrate Polymer, Journal of Agricultural and Food Chemistry，Food Function等期刊评议专家。